#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q9H446 uniprotkb:P16749 intact:EBI-748952|uniprotkb:Q9Y313|uniprotkb:Q9Y6B3|uniprotkb:A8K3W2|uniprotkb:A8MT24|ensembl:ENSP00000420357 intact:EBI-15832669|uniprotkb:Q7M6M4 psi-mi:rwdd1_human(display_long)|uniprotkb:DFRP2(gene name synonym)|uniprotkb:DRG family-regulatory protein 2(gene name synonym)|uniprotkb:RWDD1(gene name)|psi-mi:RWDD1(display_short)|uniprotkb:CGI-24(orf name)|uniprotkb:PTD013(orf name) psi-mi:icp27_hcmva(display_long)|uniprotkb:UL69(orf name) psi-mi:"MI:0018"(two hybrid) Aoyagi et al. (2010) pubmed:20133758|doi:10.1073/pnas.0914856107|imex:IM-16247 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10360(hcmva)|taxid:10360("Human cytomegalovirus (strain AD169) (HHV-5)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15832684|imex:IM-16247-1|dip:DIP-187329E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057036.2|refseq:NP_001007465.1|refseq:NP_057188.2|ensembl:ENST00000466444(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005844"(polysome)|interpro:IPR006575(RWD)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|ensembl:ENSG00000111832(gene)|interpro:IPR040213|rcsb pdb:2EBM|interpro:IPR032378|dip:DIP-34520N go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0019033"(viral tegument)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR008648(Herpesvirus transcriptional regulator)|dip:DIP-59209N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/06 2017/08/10 rogid:OvfJFwoLwchgGBS56iOdvVs0TDg9606 rogid:KWqdShTimhZpvBff8kaT/qV6Hgw10360 rigid:15X8EkB8scCl0IE80xxfyDyTiDA false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:C8BL26 uniprotkb:P16749 intact:EBI-15832730|uniprotkb:A0A076JX64|uniprotkb:Q6SW60 intact:EBI-15832669|uniprotkb:Q7M6M4 psi-mi:c8bl26_hcmv(display_long)|uniprotkb:UL82(gene name)|psi-mi:UL82(display_short)|uniprotkb:HHV5wtgp076(orf name) psi-mi:icp27_hcmva(display_long)|uniprotkb:UL69(orf name) psi-mi:"MI:0018"(two hybrid) Aoyagi et al. (2010) pubmed:20133758|doi:10.1073/pnas.0914856107|imex:IM-16247 taxid:10359(hhv-5)|taxid:10359(Human cytomegalovirus) taxid:10360(hcmva)|taxid:10360("Human cytomegalovirus (strain AD169) (HHV-5)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15832741|imex:IM-16247-3|dip:DIP-187335E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR008649(Betaherpesvirus UL8283, N-terminal)|refseq:YP_081530.1|dip:DIP-59213N go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0019033"(viral tegument)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR008648(Herpesvirus transcriptional regulator)|dip:DIP-59209N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/06 2017/08/10 rogid:EIQJgg+Np28vsu/fomS+fBPrxb410359 rogid:KWqdShTimhZpvBff8kaT/qV6Hgw10360 rigid:Yj5kprAbXLfTk5T7hK6LGkoNGNo false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:D3YRZ7 uniprotkb:P11940 intact:EBI-15832704 intact:EBI-81531|intact:EBI-28983164|ensembl:ENSP00000313007|ensembl:ENSP00000428749|ensembl:ENSP00000428840|ensembl:ENSP00000429119|ensembl:ENSP00000429790|ensembl:ENSP00000429892|ensembl:ENSP00000430012|uniprotkb:Q15097|uniprotkb:Q93004 psi-mi:d3yrz7_hcmvo(display_long)|uniprotkb:UL69(gene name)|psi-mi:UL69(display_short) psi-mi:pabp1_human(display_long)|uniprotkb:PABPC1(gene name)|psi-mi:PABPC1(display_short)|uniprotkb:PAB1(gene name synonym)|uniprotkb:PABP1(gene name synonym)|uniprotkb:PABPC2(gene name synonym)|uniprotkb:PABP(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Aoyagi et al. (2010) pubmed:20133758|doi:10.1073/pnas.0914856107|imex:IM-16247 taxid:311339(hcmvo)|taxid:311339(hcmvo) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15832712|imex:IM-16247-2|dip:DIP-187315E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0019033"(viral tegument)|interpro:IPR008648(Herpesvirus transcriptional regulator)|dip:DIP-59210N interpro:IPR006515(Polyadenylate binding protein, human types 1, 2, 3, 4)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR036053|mint:P11940|rcsb pdb:1CVJ|rcsb pdb:1G9L|rcsb pdb:1JGN|rcsb pdb:1JH4|rcsb pdb:2K8G|rcsb pdb:2RQG|rcsb pdb:2RQH|rcsb pdb:2X04|rcsb pdb:3KTP|rcsb pdb:3KTR|rcsb pdb:3KUI|rcsb pdb:3KUJ|rcsb pdb:3KUR|rcsb pdb:3KUS|rcsb pdb:3KUT|rcsb pdb:3PKN|interpro:IPR003954(RNA recognition, region 1)|rcsb pdb:3PTH|rcsb pdb:4F02|rcsb pdb:4F25|rcsb pdb:4F26|ensembl:ENSG00000070756(gene)|ensembl:ENST00000318607(transcript)|ensembl:ENST00000520142(transcript)|ensembl:ENST00000520804(transcript)|ensembl:ENST00000521865(transcript)|ensembl:ENST00000522658(transcript)|ensembl:ENST00000522720(transcript)|ensembl:ENST00000523555(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0005634"(nucleus)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031252"(cell leading edge)|go:"GO:0005737"(cytoplasm)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008143"("poly(A) binding")|go:"GO:0048255"(mRNA stabilization)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0008494"(translation activator activity)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000623"(negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002004(Polyadenylate-binding protein/Hyperplastic disc protein)|rcsb pdb:5DX1|refseq:NP_002559.2|rcsb pdb:5DX8|rcsb pdb:5DXA|rcsb pdb:5LGP|rcsb pdb:5LGQ|rcsb pdb:5LGR|rcsb pdb:5LGS|reactome:R-HSA-156827|reactome:R-HSA-429947|reactome:R-HSA-450408|reactome:R-HSA-72649|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|ensembl:ENSP00000313007|ensembl:ENSP00000430012|ensembl:ENSP00000428749|ensembl:ENSP00000429119|ensembl:ENSP00000428840|ensembl:ENSP00000429790|ensembl:ENSP00000429892|refseq:XP_005250918.1|dip:DIP-31613N psi-mi:"MI:0465"(dip) crc64:4C490B7754D3BA46 - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/06 2017/08/10 rogid:K791qoionguZmTMSKyHwE8KYHXY311339 rogid:XudTSPq2h9ckKAc48X88RVafPRU9606 rigid:iC71H1fQfn5pgwjlTYvYda2742s false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:D3YRZ7 uniprotkb:P60842 intact:EBI-15832704 intact:EBI-73449|uniprotkb:P04765|uniprotkb:Q5U018|uniprotkb:Q61516|uniprotkb:B2R6L8|uniprotkb:D3DTP9|uniprotkb:J3QLC4|ensembl:ENSP00000293831 psi-mi:d3yrz7_hcmvo(display_long)|uniprotkb:UL69(gene name)|psi-mi:UL69(display_short) psi-mi:if4a1_human(display_long)|uniprotkb:EIF4A1(gene name)|psi-mi:EIF4A1(display_short)|uniprotkb:EIF4A(gene name synonym)|uniprotkb:DDX2A(gene name synonym)|uniprotkb:ATP-dependent RNA helicase eIF4A-1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Aoyagi et al. (2010) pubmed:20133758|doi:10.1073/pnas.0914856107|imex:IM-16247 taxid:311339(hcmvo)|taxid:311339(hcmvo) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15832712|imex:IM-16247-2|dip:DIP-187315E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0019033"(viral tegument)|interpro:IPR008648(Herpesvirus transcriptional regulator)|dip:DIP-59210N refseq:NP_001407.1|refseq:NP_001191439.1|dip:DIP-29755N|ensembl:ENSG00000161960(gene)|ensembl:ENST00000293831(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0002183"(cytoplasmic translational initiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008135"(translation factor activity, RNA binding)|go:"GO:0016020"(membrane)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|interpro:IPR044728|mint:P60842|rcsb pdb:2G9N|rcsb pdb:2ZU6|rcsb pdb:3EIQ|rcsb pdb:5ZBZ|rcsb pdb:5ZC9|rcsb pdb:6ZMW|reactome:R-HSA-1169408|reactome:R-HSA-156827|reactome:R-HSA-429947|reactome:R-HSA-72649|reactome:R-HSA-72662|reactome:R-HSA-72702|reactome:R-HSA-72706 psi-mi:"MI:0465"(dip) crc64:4C490B7754D3BA46 - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/06 2017/08/10 rogid:K791qoionguZmTMSKyHwE8KYHXY311339 rogid:e+2gp47oHrpxFbrBFSM4qTf3r7E9606 rigid:iC71H1fQfn5pgwjlTYvYda2742s false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P51805 uniprotkb:P16749 intact:EBI-7135904|ensembl:ENSP00000358696|uniprotkb:Q5HY36|intact:MINT-7556947 intact:EBI-15832669|uniprotkb:Q7M6M4 psi-mi:plxa3_human(display_long)|uniprotkb:PLXNA3(gene name)|psi-mi:PLXNA3(display_short)|uniprotkb:PLXN4(gene name synonym)|uniprotkb:SEX(gene name synonym)|uniprotkb:Plexin-4(gene name synonym)|uniprotkb:Semaphorin receptor SEX(gene name synonym) psi-mi:icp27_hcmva(display_long)|uniprotkb:UL69(orf name) psi-mi:"MI:0018"(two hybrid) Aoyagi et al. (2010) pubmed:20133758|doi:10.1073/pnas.0914856107|imex:IM-16247 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10360(hcmva)|taxid:10360("Human cytomegalovirus (strain AD169) (HHV-5)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15832758|imex:IM-16247-4|dip:DIP-187328E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000130827(gene)|ensembl:ENST00000369682(transcript)|go:"GO:0002116"(semaphorin receptor complex)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016020"(membrane)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021637"(trigeminal nerve structural organization)|go:"GO:0021766"(hippocampus development)|go:"GO:0021785"(branchiomotor neuron axon guidance)|go:"GO:0021860"(pyramidal neuron development)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0048843"(negative regulation of axon extension involved in axon guidance)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0050919"(negative chemotaxis)|go:"GO:0051495"(positive regulation of cytoskeleton organization)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:1902287"(semaphorin-plexin signaling pathway involved in axon guidance)|go:"GO:1990138"(neuron projection extension)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR002165(Plexin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR013548(Plexin cytoplasmic region)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR031148|interpro:IPR036352|interpro:IPR041019|interpro:IPR041362|reactome:R-HSA-399954|reactome:R-HSA-399955|reactome:R-HSA-399956|refseq:NP_059984.3|dip:DIP-57386N go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0019033"(viral tegument)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR008648(Herpesvirus transcriptional regulator)|dip:DIP-59209N psi-mi:"MI:0465"(dip) comment:mint|comment:homomint - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/06 2017/08/10 rogid:XHm0ijYaG0j8tgLPUILBSkUVN6E9606 rogid:KWqdShTimhZpvBff8kaT/qV6Hgw10360 rigid:IKQx9Dv3CrTOUIWgInFu0z8irD4 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P49757 uniprotkb:P16749 intact:EBI-915016|uniprotkb:Q6NUQ7|uniprotkb:Q86SY1|uniprotkb:Q8WW73|uniprotkb:Q9UBG1|uniprotkb:Q9UEQ4|uniprotkb:Q9UKE8|uniprotkb:Q9UKE9|uniprotkb:Q9UKF0|uniprotkb:Q9UQJ4|uniprotkb:B4E2B1|uniprotkb:B1P2N7|uniprotkb:B1P2N8|uniprotkb:B1P2N9|uniprotkb:B1P2N5|uniprotkb:B1P2N6|intact:EBI-28966915|ensembl:ENSP00000347169|ensembl:ENSP00000451300 intact:EBI-15832669|uniprotkb:Q7M6M4 psi-mi:numb_human(display_long)|uniprotkb:Protein S171(gene name synonym)|uniprotkb:NUMB(gene name)|psi-mi:NUMB(display_short)|uniprotkb:C14orf41(gene name synonym) psi-mi:icp27_hcmva(display_long)|uniprotkb:UL69(orf name) psi-mi:"MI:0018"(two hybrid) Aoyagi et al. (2010) pubmed:20133758|doi:10.1073/pnas.0914856107|imex:IM-16247 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10360(hcmva)|taxid:10360("Human cytomegalovirus (strain AD169) (HHV-5)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15832775|imex:IM-16247-5|dip:DIP-187323E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENST00000554521|ensembl:ENSP00000450817|ensembl:ENST00000554546|ensembl:ENSP00000452416|ensembl:ENSP00000451300|ensembl:ENST00000555394|ensembl:ENSP00000451625|ensembl:ENST00000555738|ensembl:ENSP00000452069|ensembl:ENST00000557597|ensembl:ENSP00000451117|ensembl:ENST00000559312|ensembl:ENSP00000452888|ensembl:ENST00000560335|ensembl:ENSP00000453209|ensembl:ENSP00000347169|ensembl:ENST00000356296|ensembl:ENSP00000348644|ensembl:ENST00000359560|ensembl:ENSP00000352563|ensembl:ENST00000535282|ensembl:ENSP00000441258|ensembl:ENST00000544991|ensembl:ENSP00000446001|refseq:NP_001307043.1|refseq:NP_001005743.1|refseq:NP_001005744.1|refseq:NP_001005745.1|refseq:NP_003735.3|dip:DIP-37981N|ensembl:ENSG00000133961(gene)|ensembl:ENST00000355058(transcript)|ensembl:ENST00000555238(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0005925"(focal adhesion)|go:"GO:0007409"(axonogenesis)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0010008"(endosome membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021849"(neuroblast division in subventricular zone)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0034332"(adherens junction organization)|go:"GO:0045177"(apical part of cell)|go:"GO:0045294"(alpha-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099149"(regulation of postsynaptic neurotransmitter receptor internalization)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR010449(NUMB phenylalanine-rich)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016698(Numb/numb-like)|mint:P49757|rcsb pdb:5NJJ|rcsb pdb:5NJK|reactome:R-HSA-2122948|reactome:R-HSA-437239|reactome:R-HSA-5610780|reactome:R-HSA-5632684 go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0019033"(viral tegument)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR008648(Herpesvirus transcriptional regulator)|dip:DIP-59209N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/06 2017/08/10 rogid:X+CHBhp67o6ROnf86RCtXlCAaF49606 rogid:KWqdShTimhZpvBff8kaT/qV6Hgw10360 rigid:nLBl5bkegMkk/M5vyttaCs/c8Rk false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P18615 uniprotkb:P16749 intact:EBI-348444|uniprotkb:B4DUN1|uniprotkb:B4DYX9|ensembl:ENSP00000364578|ensembl:ENSP00000372660|ensembl:ENSP00000372834|ensembl:ENSP00000393005|ensembl:ENSP00000394879|ensembl:ENSP00000403623|uniprotkb:Q5JP74|uniprotkb:Q5JP75|uniprotkb:Q96F56|uniprotkb:Q9NPK2|uniprotkb:A2BE08 intact:EBI-15832669|uniprotkb:Q7M6M4 psi-mi:nelfe_human(display_long)|uniprotkb:NELFE(gene name)|psi-mi:NELFE(display_short)|uniprotkb:RD(gene name synonym)|uniprotkb:RDBP(gene name synonym)|uniprotkb:RNA-binding protein RD(gene name synonym) psi-mi:icp27_hcmva(display_long)|uniprotkb:UL69(orf name) psi-mi:"MI:0018"(two hybrid) Aoyagi et al. (2010) pubmed:20133758|doi:10.1073/pnas.0914856107|imex:IM-16247 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10360(hcmva)|taxid:10360("Human cytomegalovirus (strain AD169) (HHV-5)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15832792|imex:IM-16247-6|dip:DIP-187318E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002895.3|ensembl:ENSG00000204356(gene)|ensembl:ENSG00000206268(gene)|ensembl:ENSG00000206357(gene)|ensembl:ENSG00000229363(gene)|ensembl:ENSG00000231044(gene)|ensembl:ENSG00000233801(gene)|ensembl:ENST00000375429(transcript)|ensembl:ENST00000383174(transcript)|ensembl:ENST00000383343(transcript)|ensembl:ENST00000429857(transcript)|ensembl:ENST00000448628(transcript)|ensembl:ENST00000457397(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0032021"(NELF complex)|go:"GO:0005634"(nucleus)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033102|interpro:IPR034637|interpro:IPR035979|mint:P18615|rcsb pdb:1X5P|rcsb pdb:2BZ2|rcsb pdb:2JX2|rcsb pdb:5OOB|rcsb pdb:6GML|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-75955|dip:DIP-32669N go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0019033"(viral tegument)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR008648(Herpesvirus transcriptional regulator)|dip:DIP-59209N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/06 2017/08/10 rogid:AaBoPxRk9kFoijQiehOZtEZ+/OI9606 rogid:KWqdShTimhZpvBff8kaT/qV6Hgw10360 rigid:dSoyVj0XsWHgGAlTcu3h2R0+d6M false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q6UUV7 uniprotkb:P16749 intact:EBI-3453588|uniprotkb:Q9H6U2|uniprotkb:Q6DK61|uniprotkb:Q6DK62|uniprotkb:Q8NF38|ensembl:ENSP00000268184 intact:EBI-15832669|uniprotkb:Q7M6M4 psi-mi:crtc3_human(display_long)|uniprotkb:CRTC3(gene name)|psi-mi:CRTC3(display_short)|uniprotkb:TORC3(gene name synonym)|uniprotkb:Transducer of regulated cAMP response element-binding protein 3(gene name synonym) psi-mi:icp27_hcmva(display_long)|uniprotkb:UL69(orf name) psi-mi:"MI:0018"(two hybrid) Aoyagi et al. (2010) pubmed:20133758|doi:10.1073/pnas.0914856107|imex:IM-16247 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10360(hcmva)|taxid:10360("Human cytomegalovirus (strain AD169) (HHV-5)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15832809|imex:IM-16247-7|dip:DIP-187319E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001036039.1|refseq:NP_073606.3|ensembl:ENSP00000268184|ensembl:ENST00000420329|ensembl:ENSP00000416573|dip:DIP-59211N|ensembl:ENSG00000140577(gene)|ensembl:ENST00000268184(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|interpro:IPR024786|reactome:R-HSA-2151201|reactome:R-HSA-400253|reactome:R-HSA-9707616|go:"GO:0005829"(cytosol)|go:"GO:0008140"(cAMP response element binding protein binding)|go:"GO:0032793"(positive regulation of CREB transcription factor activity)|go:"GO:0042116"(macrophage activation)|go:"GO:0043951"(negative regulation of cAMP-mediated signaling)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050995"(negative regulation of lipid catabolic process)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0097009"(energy homeostasis)|interpro:IPR024783|interpro:IPR024784|interpro:IPR024785 go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0019033"(viral tegument)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR008648(Herpesvirus transcriptional regulator)|dip:DIP-59209N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/06 2017/08/10 rogid:OHoNJjikyJ3RLDd+Y23mUXbtLDA9606 rogid:KWqdShTimhZpvBff8kaT/qV6Hgw10360 rigid:G8UR0nun7EZcQSsPWu0ovJRAe8A false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P60842 uniprotkb:P11940 intact:EBI-73449|uniprotkb:P04765|uniprotkb:Q5U018|uniprotkb:Q61516|uniprotkb:B2R6L8|uniprotkb:D3DTP9|uniprotkb:J3QLC4|ensembl:ENSP00000293831 intact:EBI-81531|intact:EBI-28983164|ensembl:ENSP00000313007|ensembl:ENSP00000428749|ensembl:ENSP00000428840|ensembl:ENSP00000429119|ensembl:ENSP00000429790|ensembl:ENSP00000429892|ensembl:ENSP00000430012|uniprotkb:Q15097|uniprotkb:Q93004 psi-mi:if4a1_human(display_long)|uniprotkb:EIF4A1(gene name)|psi-mi:EIF4A1(display_short)|uniprotkb:EIF4A(gene name synonym)|uniprotkb:DDX2A(gene name synonym)|uniprotkb:ATP-dependent RNA helicase eIF4A-1(gene name synonym) psi-mi:pabp1_human(display_long)|uniprotkb:PABPC1(gene name)|psi-mi:PABPC1(display_short)|uniprotkb:PAB1(gene name synonym)|uniprotkb:PABP1(gene name synonym)|uniprotkb:PABPC2(gene name synonym)|uniprotkb:PABP(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Aoyagi et al. (2010) pubmed:20133758|doi:10.1073/pnas.0914856107|imex:IM-16247 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15832826|imex:IM-16247-8|dip:DIP-187315E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001407.1|refseq:NP_001191439.1|dip:DIP-29755N|ensembl:ENSG00000161960(gene)|ensembl:ENST00000293831(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0002183"(cytoplasmic translational initiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008135"(translation factor activity, RNA binding)|go:"GO:0016020"(membrane)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|interpro:IPR044728|mint:P60842|rcsb pdb:2G9N|rcsb pdb:2ZU6|rcsb pdb:3EIQ|rcsb pdb:5ZBZ|rcsb pdb:5ZC9|rcsb pdb:6ZMW|reactome:R-HSA-1169408|reactome:R-HSA-156827|reactome:R-HSA-429947|reactome:R-HSA-72649|reactome:R-HSA-72662|reactome:R-HSA-72702|reactome:R-HSA-72706 interpro:IPR006515(Polyadenylate binding protein, human types 1, 2, 3, 4)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR036053|mint:P11940|rcsb pdb:1CVJ|rcsb pdb:1G9L|rcsb pdb:1JGN|rcsb pdb:1JH4|rcsb pdb:2K8G|rcsb pdb:2RQG|rcsb pdb:2RQH|rcsb pdb:2X04|rcsb pdb:3KTP|rcsb pdb:3KTR|rcsb pdb:3KUI|rcsb pdb:3KUJ|rcsb pdb:3KUR|rcsb pdb:3KUS|rcsb pdb:3KUT|rcsb pdb:3PKN|interpro:IPR003954(RNA recognition, region 1)|rcsb pdb:3PTH|rcsb pdb:4F02|rcsb pdb:4F25|rcsb pdb:4F26|ensembl:ENSG00000070756(gene)|ensembl:ENST00000318607(transcript)|ensembl:ENST00000520142(transcript)|ensembl:ENST00000520804(transcript)|ensembl:ENST00000521865(transcript)|ensembl:ENST00000522658(transcript)|ensembl:ENST00000522720(transcript)|ensembl:ENST00000523555(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0005634"(nucleus)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031252"(cell leading edge)|go:"GO:0005737"(cytoplasm)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008143"("poly(A) binding")|go:"GO:0048255"(mRNA stabilization)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0008494"(translation activator activity)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000623"(negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002004(Polyadenylate-binding protein/Hyperplastic disc protein)|rcsb pdb:5DX1|refseq:NP_002559.2|rcsb pdb:5DX8|rcsb pdb:5DXA|rcsb pdb:5LGP|rcsb pdb:5LGQ|rcsb pdb:5LGR|rcsb pdb:5LGS|reactome:R-HSA-156827|reactome:R-HSA-429947|reactome:R-HSA-450408|reactome:R-HSA-72649|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|ensembl:ENSP00000313007|ensembl:ENSP00000430012|ensembl:ENSP00000428749|ensembl:ENSP00000429119|ensembl:ENSP00000428840|ensembl:ENSP00000429790|ensembl:ENSP00000429892|refseq:XP_005250918.1|dip:DIP-31613N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/06 2017/08/10 rogid:e+2gp47oHrpxFbrBFSM4qTf3r7E9606 rogid:XudTSPq2h9ckKAc48X88RVafPRU9606 rigid:iC71H1fQfn5pgwjlTYvYda2742s false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P60842 uniprotkb:D3YRZ7 intact:EBI-73449|uniprotkb:P04765|uniprotkb:Q5U018|uniprotkb:Q61516|uniprotkb:B2R6L8|uniprotkb:D3DTP9|uniprotkb:J3QLC4|ensembl:ENSP00000293831 intact:EBI-15832704 psi-mi:if4a1_human(display_long)|uniprotkb:EIF4A1(gene name)|psi-mi:EIF4A1(display_short)|uniprotkb:EIF4A(gene name synonym)|uniprotkb:DDX2A(gene name synonym)|uniprotkb:ATP-dependent RNA helicase eIF4A-1(gene name synonym) psi-mi:d3yrz7_hcmvo(display_long)|uniprotkb:UL69(gene name)|psi-mi:UL69(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Aoyagi et al. (2010) pubmed:20133758|doi:10.1073/pnas.0914856107|imex:IM-16247 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:311339(hcmvo)|taxid:311339(hcmvo) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15832826|imex:IM-16247-8|dip:DIP-187315E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001407.1|refseq:NP_001191439.1|dip:DIP-29755N|ensembl:ENSG00000161960(gene)|ensembl:ENST00000293831(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0002183"(cytoplasmic translational initiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008135"(translation factor activity, RNA binding)|go:"GO:0016020"(membrane)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|interpro:IPR044728|mint:P60842|rcsb pdb:2G9N|rcsb pdb:2ZU6|rcsb pdb:3EIQ|rcsb pdb:5ZBZ|rcsb pdb:5ZC9|rcsb pdb:6ZMW|reactome:R-HSA-1169408|reactome:R-HSA-156827|reactome:R-HSA-429947|reactome:R-HSA-72649|reactome:R-HSA-72662|reactome:R-HSA-72702|reactome:R-HSA-72706 go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0019033"(viral tegument)|interpro:IPR008648(Herpesvirus transcriptional regulator)|dip:DIP-59210N psi-mi:"MI:0465"(dip) - crc64:4C490B7754D3BA46 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/06 2017/08/10 rogid:e+2gp47oHrpxFbrBFSM4qTf3r7E9606 rogid:K791qoionguZmTMSKyHwE8KYHXY311339 rigid:iC71H1fQfn5pgwjlTYvYda2742s false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P62993-1 uniprotkb:P16749 intact:EBI-15787932|ensembl:ENSP00000339007|ensembl:ENSP00000376345|ensembl:ENSP00000376347|ensembl:ENSP00000496913|uniprotkb:P29354-1 intact:EBI-15832669|uniprotkb:Q7M6M4 psi-mi:p62993-1(display_long)|uniprotkb:GRB2(gene name)|psi-mi:GRB2(display_short)|uniprotkb:ASH(gene name synonym)|uniprotkb:Adapter protein GRB2(gene name synonym)|uniprotkb:Protein Ash(gene name synonym)|uniprotkb:SH2/SH3 adapter GRB2(gene name synonym)|uniprotkb:Ash-L(isoform synonym) psi-mi:icp27_hcmva(display_long)|uniprotkb:UL69(orf name) psi-mi:"MI:0018"(two hybrid) Aoyagi et al. (2010) pubmed:20133758|doi:10.1073/pnas.0914856107|imex:IM-16247 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10360(hcmva)|taxid:10360("Human cytomegalovirus (strain AD169) (HHV-5)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15832844|imex:IM-16247-9|dip:DIP-187330E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000177885(gene)|ensembl:ENST00000316804(transcript)|ensembl:ENST00000392562(transcript)|ensembl:ENST00000392564(transcript)|ensembl:ENST00000648046(transcript)|intact:EBI-401755(isoform-parent) go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0019033"(viral tegument)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR008648(Herpesvirus transcriptional regulator)|dip:DIP-59209N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/06 2017/08/10 rogid:SLnslQ7NHbnuK06nMVuRvJpoOA49606 rogid:KWqdShTimhZpvBff8kaT/qV6Hgw10360 rigid:Z9/2QKWkHgkeM+LfH4Az4ueX1Ws false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P07858 uniprotkb:P16749 intact:EBI-715062|uniprotkb:Q503A6|uniprotkb:Q96D87|uniprotkb:B3KRR5|uniprotkb:B3KQR5|ensembl:ENSP00000503300|ensembl:ENSP00000503435|ensembl:ENSP00000503487|ensembl:ENSP00000503513|ensembl:ENSP00000503578|ensembl:ENSP00000503608|ensembl:ENSP00000503652|ensembl:ENSP00000503674|ensembl:ENSP00000503858|ensembl:ENSP00000503909|ensembl:ENSP00000504161|ensembl:ENSP00000504226|ensembl:ENSP00000504336|ensembl:ENSP00000504480|ensembl:ENSP00000504638|ensembl:ENSP00000504659|ensembl:ENSP00000504797|ensembl:ENSP00000503280|ensembl:ENSP00000342070|ensembl:ENSP00000345672|ensembl:ENSP00000431143|ensembl:ENSP00000431518|ensembl:ENSP00000432077|ensembl:ENSP00000432244|ensembl:ENSP00000432408|ensembl:ENSP00000433215|ensembl:ENSP00000433379|ensembl:ENSP00000433929|ensembl:ENSP00000434217|ensembl:ENSP00000434725|ensembl:ENSP00000435074|ensembl:ENSP00000435105|ensembl:ENSP00000435260|ensembl:ENSP00000435886|ensembl:ENSP00000473301|ensembl:ENSP00000502963|ensembl:ENSP00000503006|ensembl:ENSP00000503052|ensembl:ENSP00000503078|ensembl:ENSP00000503174 intact:EBI-15832669|uniprotkb:Q7M6M4 psi-mi:catb_human(display_long)|uniprotkb:Cathepsin B1(gene name synonym)|uniprotkb:APP secretase(gene name synonym)|uniprotkb:CTSB(gene name)|psi-mi:CTSB(display_short)|uniprotkb:CPSB(gene name synonym) psi-mi:icp27_hcmva(display_long)|uniprotkb:UL69(orf name) psi-mi:"MI:0018"(two hybrid) Aoyagi et al. (2010) pubmed:20133758|doi:10.1073/pnas.0914856107|imex:IM-16247 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10360(hcmva)|taxid:10360("Human cytomegalovirus (strain AD169) (HHV-5)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15832930|imex:IM-16247-14|dip:DIP-187326E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001899.1|refseq:NP_680090.1|refseq:NP_680091.1|refseq:NP_680092.1|refseq:NP_680093.1|refseq:XP_011542114.1|refseq:XP_016868586.1|refseq:XP_016868587.1|refseq:XP_016868588.1|refseq:XP_016868589.1|ensembl:ENST00000345125(transcript)|ensembl:ENST00000353047(transcript)|ensembl:ENST00000524654(transcript)|ensembl:ENST00000526481(transcript)|ensembl:ENST00000526645(transcript)|ensembl:ENST00000527215(transcript)|ensembl:ENST00000534382(transcript)|ensembl:ENST00000527243(transcript)|ensembl:ENST00000534510(transcript)|ensembl:ENST00000676691(transcript)|ensembl:ENST00000676755(transcript)|ensembl:ENST00000676825(transcript)|ensembl:ENST00000676843(transcript)|ensembl:ENST00000676952(transcript)|ensembl:ENST00000677082(transcript)|ensembl:ENST00000677366(transcript)|ensembl:ENST00000677415(transcript)|ensembl:ENST00000528965(transcript)|ensembl:ENST00000530296(transcript)|ensembl:ENST00000530640(transcript)|ensembl:ENST00000677418(transcript)|ensembl:ENST00000677544(transcript)|ensembl:ENST00000677650(transcript)|ensembl:ENST00000677671(transcript)|ensembl:ENST00000677819(transcript)|ensembl:ENST00000677873(transcript)|ensembl:ENST00000678092(transcript)|ensembl:ENST00000678145(transcript)|ensembl:ENST00000678242(transcript)|ensembl:ENST00000531089(transcript)|ensembl:ENST00000678357(transcript)|ensembl:ENST00000531502(transcript)|ensembl:ENST00000678615(transcript)|ensembl:ENST00000532392(transcript)|ensembl:ENST00000678929(transcript)|ensembl:ENST00000532656(transcript)|ensembl:ENST00000533455(transcript)|ensembl:ENST00000679051(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005622"(intracellular anatomical structure)|go:"GO:0005764"(lysosome)|go:"GO:0006508"(proteolysis)|go:"GO:0006590"(thyroid hormone generation)|go:"GO:0008233"(peptidase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030574"(collagen catabolic process)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0036021"(endolysosome lumen)|go:"GO:0042470"(melanosome)|go:"GO:0042981"(regulation of apoptotic process)|ensembl:ENST00000679128(transcript)|go:"GO:0043394"(proteoglycan binding)|ensembl:ENST00000679140(transcript)|go:"GO:0046697"(decidualization)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0005518"(collagen binding)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051603"(proteolysis involved in cellular protein catabolic process)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097067"(cellular response to thyroid hormone stimulus)|ensembl:ENSG00000164733(gene)|interpro:IPR000169(Peptidase, cysteine peptidase active site)|interpro:IPR000668(Peptidase C1A, papain C-terminal)|interpro:IPR012599(Peptidase C1A, propeptide)|interpro:IPR025660|interpro:IPR025661|interpro:IPR038765|mint:P07858|rcsb pdb:1CSB|rcsb pdb:1GMY|rcsb pdb:1HUC|rcsb pdb:1PBH|rcsb pdb:2IPP|rcsb pdb:2PBH|rcsb pdb:3AI8|rcsb pdb:3CBJ|rcsb pdb:3CBK|rcsb pdb:3K9M|rcsb pdb:3PBH|rcsb pdb:5MBL|rcsb pdb:5MBM|rcsb pdb:6AY2|reactome:R-HSA-1442490|reactome:R-HSA-1679131|reactome:R-HSA-2022090|reactome:R-HSA-2132295|reactome:R-HSA-6798695|go:"GO:1904813"(ficolin-1-rich granule lumen)|refseq:XP_006716307.1|refseq:XP_006716308.1|dip:DIP-42785N go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0019033"(viral tegument)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR008648(Herpesvirus transcriptional regulator)|dip:DIP-59209N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/06 2017/08/10 rogid:TdxD7Gf4BmlJcfUSULihf9W3sKQ9606 rogid:KWqdShTimhZpvBff8kaT/qV6Hgw10360 rigid:9PIerKaTs3RiF7n1GsfIXWJxn4c false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P11940 uniprotkb:P60842 intact:EBI-81531|intact:EBI-28983164|ensembl:ENSP00000313007|ensembl:ENSP00000428749|ensembl:ENSP00000428840|ensembl:ENSP00000429119|ensembl:ENSP00000429790|ensembl:ENSP00000429892|ensembl:ENSP00000430012|uniprotkb:Q15097|uniprotkb:Q93004 intact:EBI-73449|uniprotkb:P04765|uniprotkb:Q5U018|uniprotkb:Q61516|uniprotkb:B2R6L8|uniprotkb:D3DTP9|uniprotkb:J3QLC4|ensembl:ENSP00000293831 psi-mi:pabp1_human(display_long)|uniprotkb:PABPC1(gene name)|psi-mi:PABPC1(display_short)|uniprotkb:PAB1(gene name synonym)|uniprotkb:PABP1(gene name synonym)|uniprotkb:PABPC2(gene name synonym)|uniprotkb:PABP(gene name synonym) psi-mi:if4a1_human(display_long)|uniprotkb:EIF4A1(gene name)|psi-mi:EIF4A1(display_short)|uniprotkb:EIF4A(gene name synonym)|uniprotkb:DDX2A(gene name synonym)|uniprotkb:ATP-dependent RNA helicase eIF4A-1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Aoyagi et al. (2010) pubmed:20133758|doi:10.1073/pnas.0914856107|imex:IM-16247 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15832912|imex:IM-16247-13|dip:DIP-187315E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR006515(Polyadenylate binding protein, human types 1, 2, 3, 4)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR036053|mint:P11940|rcsb pdb:1CVJ|rcsb pdb:1G9L|rcsb pdb:1JGN|rcsb pdb:1JH4|rcsb pdb:2K8G|rcsb pdb:2RQG|rcsb pdb:2RQH|rcsb pdb:2X04|rcsb pdb:3KTP|rcsb pdb:3KTR|rcsb pdb:3KUI|rcsb pdb:3KUJ|rcsb pdb:3KUR|rcsb pdb:3KUS|rcsb pdb:3KUT|rcsb pdb:3PKN|interpro:IPR003954(RNA recognition, region 1)|rcsb pdb:3PTH|rcsb pdb:4F02|rcsb pdb:4F25|rcsb pdb:4F26|ensembl:ENSG00000070756(gene)|ensembl:ENST00000318607(transcript)|ensembl:ENST00000520142(transcript)|ensembl:ENST00000520804(transcript)|ensembl:ENST00000521865(transcript)|ensembl:ENST00000522658(transcript)|ensembl:ENST00000522720(transcript)|ensembl:ENST00000523555(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0005634"(nucleus)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031252"(cell leading edge)|go:"GO:0005737"(cytoplasm)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008143"("poly(A) binding")|go:"GO:0048255"(mRNA stabilization)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0008494"(translation activator activity)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000623"(negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002004(Polyadenylate-binding protein/Hyperplastic disc protein)|rcsb pdb:5DX1|refseq:NP_002559.2|rcsb pdb:5DX8|rcsb pdb:5DXA|rcsb pdb:5LGP|rcsb pdb:5LGQ|rcsb pdb:5LGR|rcsb pdb:5LGS|reactome:R-HSA-156827|reactome:R-HSA-429947|reactome:R-HSA-450408|reactome:R-HSA-72649|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|ensembl:ENSP00000313007|ensembl:ENSP00000430012|ensembl:ENSP00000428749|ensembl:ENSP00000429119|ensembl:ENSP00000428840|ensembl:ENSP00000429790|ensembl:ENSP00000429892|refseq:XP_005250918.1|dip:DIP-31613N refseq:NP_001407.1|refseq:NP_001191439.1|dip:DIP-29755N|ensembl:ENSG00000161960(gene)|ensembl:ENST00000293831(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0002183"(cytoplasmic translational initiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008135"(translation factor activity, RNA binding)|go:"GO:0016020"(membrane)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|interpro:IPR044728|mint:P60842|rcsb pdb:2G9N|rcsb pdb:2ZU6|rcsb pdb:3EIQ|rcsb pdb:5ZBZ|rcsb pdb:5ZC9|rcsb pdb:6ZMW|reactome:R-HSA-1169408|reactome:R-HSA-156827|reactome:R-HSA-429947|reactome:R-HSA-72649|reactome:R-HSA-72662|reactome:R-HSA-72702|reactome:R-HSA-72706 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/06 2017/08/10 rogid:XudTSPq2h9ckKAc48X88RVafPRU9606 rogid:e+2gp47oHrpxFbrBFSM4qTf3r7E9606 rigid:iC71H1fQfn5pgwjlTYvYda2742s false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P11940 uniprotkb:D3YRZ7 intact:EBI-81531|intact:EBI-28983164|ensembl:ENSP00000313007|ensembl:ENSP00000428749|ensembl:ENSP00000428840|ensembl:ENSP00000429119|ensembl:ENSP00000429790|ensembl:ENSP00000429892|ensembl:ENSP00000430012|uniprotkb:Q15097|uniprotkb:Q93004 intact:EBI-15832704 psi-mi:pabp1_human(display_long)|uniprotkb:PABPC1(gene name)|psi-mi:PABPC1(display_short)|uniprotkb:PAB1(gene name synonym)|uniprotkb:PABP1(gene name synonym)|uniprotkb:PABPC2(gene name synonym)|uniprotkb:PABP(gene name synonym) psi-mi:d3yrz7_hcmvo(display_long)|uniprotkb:UL69(gene name)|psi-mi:UL69(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Aoyagi et al. (2010) pubmed:20133758|doi:10.1073/pnas.0914856107|imex:IM-16247 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:311339(hcmvo)|taxid:311339(hcmvo) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15832912|imex:IM-16247-13|dip:DIP-187315E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR006515(Polyadenylate binding protein, human types 1, 2, 3, 4)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR036053|mint:P11940|rcsb pdb:1CVJ|rcsb pdb:1G9L|rcsb pdb:1JGN|rcsb pdb:1JH4|rcsb pdb:2K8G|rcsb pdb:2RQG|rcsb pdb:2RQH|rcsb pdb:2X04|rcsb pdb:3KTP|rcsb pdb:3KTR|rcsb pdb:3KUI|rcsb pdb:3KUJ|rcsb pdb:3KUR|rcsb pdb:3KUS|rcsb pdb:3KUT|rcsb pdb:3PKN|interpro:IPR003954(RNA recognition, region 1)|rcsb pdb:3PTH|rcsb pdb:4F02|rcsb pdb:4F25|rcsb pdb:4F26|ensembl:ENSG00000070756(gene)|ensembl:ENST00000318607(transcript)|ensembl:ENST00000520142(transcript)|ensembl:ENST00000520804(transcript)|ensembl:ENST00000521865(transcript)|ensembl:ENST00000522658(transcript)|ensembl:ENST00000522720(transcript)|ensembl:ENST00000523555(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0005634"(nucleus)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031252"(cell leading edge)|go:"GO:0005737"(cytoplasm)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008143"("poly(A) binding")|go:"GO:0048255"(mRNA stabilization)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0008494"(translation activator activity)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000623"(negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002004(Polyadenylate-binding protein/Hyperplastic disc protein)|rcsb pdb:5DX1|refseq:NP_002559.2|rcsb pdb:5DX8|rcsb pdb:5DXA|rcsb pdb:5LGP|rcsb pdb:5LGQ|rcsb pdb:5LGR|rcsb pdb:5LGS|reactome:R-HSA-156827|reactome:R-HSA-429947|reactome:R-HSA-450408|reactome:R-HSA-72649|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|ensembl:ENSP00000313007|ensembl:ENSP00000430012|ensembl:ENSP00000428749|ensembl:ENSP00000429119|ensembl:ENSP00000428840|ensembl:ENSP00000429790|ensembl:ENSP00000429892|refseq:XP_005250918.1|dip:DIP-31613N go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0019033"(viral tegument)|interpro:IPR008648(Herpesvirus transcriptional regulator)|dip:DIP-59210N psi-mi:"MI:0465"(dip) - crc64:4C490B7754D3BA46 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/06 2017/08/10 rogid:XudTSPq2h9ckKAc48X88RVafPRU9606 rogid:K791qoionguZmTMSKyHwE8KYHXY311339 rigid:iC71H1fQfn5pgwjlTYvYda2742s false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P20592 uniprotkb:P16749 intact:EBI-10200618|uniprotkb:B7Z5D3|uniprotkb:D3DSI7|ensembl:ENSP00000333657|ensembl:ENSP00000389256|ensembl:ENSP00000506423 intact:EBI-15832669|uniprotkb:Q7M6M4 psi-mi:mx2_human(display_long)|uniprotkb:MX2(gene name)|psi-mi:MX2(display_short)|uniprotkb:Interferon-regulated resistance GTP-binding protein MxB(gene name synonym)|uniprotkb:Myxovirus resistance protein 2(gene name synonym)|uniprotkb:p78-related protein(gene name synonym) psi-mi:icp27_hcmva(display_long)|uniprotkb:UL69(orf name) psi-mi:"MI:0018"(two hybrid) Aoyagi et al. (2010) pubmed:20133758|doi:10.1073/pnas.0914856107|imex:IM-16247 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10360(hcmva)|taxid:10360("Human cytomegalovirus (strain AD169) (HHV-5)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15832895|imex:IM-16247-12|dip:DIP-187324E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002454.1|refseq:XP_005261040.1|refseq:XP_005261041.1|refseq:XP_011527873.1|refseq:XP_011527874.1|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006952"(defense response)|go:"GO:0008017"(microtubule binding)|go:"GO:0009615"(response to virus)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015031"(protein transport)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016185"(synaptic vesicle budding from presynaptic endocytic zone membrane)|go:"GO:0030424"(axon)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031623"(receptor internalization)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0035455"(response to interferon-alpha)|go:"GO:0044327"(dendritic spine head)|go:"GO:0045087"(innate immune response)|go:"GO:0046822"(regulation of nucleocytoplasmic transport)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0051028"(mRNA transport)|go:"GO:0051607"(defense response to virus)|interpro:IPR001401(Dynamin, GTPase region)|interpro:IPR003130(Dynamin GTPase effector)|interpro:IPR019762|interpro:IPR020850|interpro:IPR022812|interpro:IPR027417|interpro:IPR030381|rcsb pdb:4WHJ|rcsb pdb:4X0R|rcsb pdb:5UOT|reactome:R-HSA-1169408|reactome:R-HSA-909733|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0061025"(membrane fusion)|go:"GO:0098793"(presynapse)|go:"GO:0098844"(postsynaptic endocytic zone membrane)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|interpro:IPR000375(Dynamin central region)|ensembl:ENSG00000183486(gene)|ensembl:ENST00000330714(transcript)|ensembl:ENST00000435611(transcript)|ensembl:ENST00000680862(transcript)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0003374"(dynamin family protein polymerization involved in mitochondrial fission)|dip:DIP-59212N go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0019033"(viral tegument)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR008648(Herpesvirus transcriptional regulator)|dip:DIP-59209N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/06 2017/08/10 rogid:nEQNwCd71IiwE4x20PPmVexh6bE9606 rogid:KWqdShTimhZpvBff8kaT/qV6Hgw10360 rigid:jSoUz6uJ9k27eACmGWmiebDUMb0 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9P0J0 uniprotkb:P16749 intact:EBI-372742|uniprotkb:Q6PKI0|uniprotkb:Q9H2L3|uniprotkb:Q9Y327|uniprotkb:B4DF76|uniprotkb:K7EK58|ensembl:ENSP00000423673 intact:EBI-15832669|uniprotkb:Q7M6M4 psi-mi:nduad_human(display_long)|uniprotkb:NDUFA13(gene name)|psi-mi:NDUFA13(display_short)|uniprotkb:CGI-39(orf name)|uniprotkb:CDA016(orf name)|uniprotkb:NADH-ubiquinone oxidoreductase B16.6 subunit(gene name synonym)|uniprotkb:Complex I-B16.6(gene name synonym)|uniprotkb:Gene associated with retinoic and interferon-induced mortality 19 protein(gene name synonym)|uniprotkb:Cell death regulatory protein GRIM-19(gene name synonym)|uniprotkb:GRIM19(gene name synonym) psi-mi:icp27_hcmva(display_long)|uniprotkb:UL69(orf name) psi-mi:"MI:0018"(two hybrid) Aoyagi et al. (2010) pubmed:20133758|doi:10.1073/pnas.0914856107|imex:IM-16247 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10360(hcmva)|taxid:10360("Human cytomegalovirus (strain AD169) (HHV-5)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15832861|imex:IM-16247-10|dip:DIP-187325E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057049.5|go:"GO:0005524"(ATP binding)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0010952"(positive regulation of peptidase activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045039"(protein insertion into mitochondrial inner membrane)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0005654"(nucleoplasm)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0005737"(cytoplasm)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR009346(GRIM-19)|mint:Q9P0J0|rcsb pdb:5XTB|rcsb pdb:5XTC|go:"GO:0005739"(mitochondrion)|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005746"(mitochondrial respirasome)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|ensembl:ENSG00000186010(gene)|ensembl:ENST00000507754(transcript)|go:"GO:0003954"(NADH dehydrogenase activity)|dip:DIP-31180N go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0019033"(viral tegument)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR008648(Herpesvirus transcriptional regulator)|dip:DIP-59209N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/06 2017/08/10 rogid:X5AsKHIxU5kpNVjY37UbZXG/Kns9606 rogid:KWqdShTimhZpvBff8kaT/qV6Hgw10360 rigid:8PVOsjWGop5Vz5i8pFK2JjcsJ3s false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P08123 uniprotkb:P16749 intact:EBI-983038|uniprotkb:P02464|uniprotkb:Q13897|uniprotkb:Q13997|ensembl:ENSP00000297268|uniprotkb:Q7Z5S6|uniprotkb:Q9UEB6|uniprotkb:Q9UEF9|uniprotkb:Q9UM83|uniprotkb:Q9UMI1|uniprotkb:Q9UML5|uniprotkb:Q9UMM6|uniprotkb:Q9UPH0|uniprotkb:Q13998|uniprotkb:Q14038|uniprotkb:Q14057|uniprotkb:Q15177|uniprotkb:Q15947|uniprotkb:Q16480|uniprotkb:Q16511 intact:EBI-15832669|uniprotkb:Q7M6M4 psi-mi:co1a2_human(display_long)|uniprotkb:Alpha-2 type I collagen(gene name synonym)|uniprotkb:COL1A2(gene name)|psi-mi:COL1A2(display_short) psi-mi:icp27_hcmva(display_long)|uniprotkb:UL69(orf name) psi-mi:"MI:0018"(two hybrid) Aoyagi et al. (2010) pubmed:20133758|doi:10.1073/pnas.0914856107|imex:IM-16247 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10360(hcmva)|taxid:10360("Human cytomegalovirus (strain AD169) (HHV-5)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15832878|imex:IM-16247-11|dip:DIP-187334E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000164692(gene)|ensembl:ENST00000297268(transcript)|go:"GO:0001501"(skeletal system development)|go:"GO:0001568"(blood vessel development)|go:"GO:0002020"(protease binding)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005576"(extracellular region)|go:"GO:0005584"(collagen type I trimer)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0030020"(extracellular matrix structural constituent conferring tensile strength)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0030282"(bone mineralization)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031012"(extracellular matrix)|go:"GO:0032963"(collagen metabolic process)|go:"GO:0042476"(odontogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043589"(skin morphogenesis)|go:"GO:0046332"(SMAD binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048407"(platelet-derived growth factor binding)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070208"(protein heterotrimerization)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0085029"(extracellular matrix assembly)|interpro:IPR000885(Fibrillar collagen, C-terminal)|interpro:IPR008160(Collagen triple helix repeat)|mint:P08123|rcsb pdb:5CTD|rcsb pdb:5CTI|rcsb pdb:5CVA|rcsb pdb:6JEC|reactome:R-HSA-114604|reactome:R-HSA-1442490|reactome:R-HSA-1474244|reactome:R-HSA-1650814|reactome:R-HSA-198933|reactome:R-HSA-2022090|reactome:R-HSA-202733|reactome:R-HSA-216083|reactome:R-HSA-2214320|reactome:R-HSA-2243919|reactome:R-HSA-3000170|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-3000480|reactome:R-HSA-430116|reactome:R-HSA-6785807|reactome:R-HSA-75892|reactome:R-HSA-76009|reactome:R-HSA-8874081|reactome:R-HSA-8948216|refseq:NP_000080.2|dip:DIP-36079N go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0019033"(viral tegument)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR008648(Herpesvirus transcriptional regulator)|dip:DIP-59209N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/06 2017/08/10 rogid:vRxr0tOWziIyQf9or1gC6sDlN8I9606 rogid:KWqdShTimhZpvBff8kaT/qV6Hgw10360 rigid:2SvluNrG7chPFOgFdorRA5/0DmE false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9UHK0 uniprotkb:P16749 intact:EBI-2563549|uniprotkb:Q8WVM5|uniprotkb:Q96SG1|ensembl:ENSP00000368459 intact:EBI-15832669|uniprotkb:Q7M6M4 psi-mi:nufp1_human(display_long)|uniprotkb:Nuclear FMRP-interacting protein 1(gene name synonym)|uniprotkb:NUFIP1(gene name)|psi-mi:NUFIP1(display_short) psi-mi:icp27_hcmva(display_long)|uniprotkb:UL69(orf name) psi-mi:"MI:0018"(two hybrid) Aoyagi et al. (2010) pubmed:20133758|doi:10.1073/pnas.0914856107|imex:IM-16247 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10360(hcmva)|taxid:10360("Human cytomegalovirus (strain AD169) (HHV-5)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15832947|imex:IM-16247-15|dip:DIP-187320E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036477.2|ensembl:ENSG00000083635(gene)|ensembl:ENST00000379161(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0001650"(fibrillar center)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0016363"(nuclear matrix)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0051117"(ATPase binding)|go:"GO:0070761"(pre-snoRNP complex)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR019496|interpro:IPR022755|interpro:IPR039136|mint:Q9UHK0|rcsb pdb:5L85|go:"GO:0005730"(nucleolus)|go:"GO:0006396"(RNA processing)|dip:DIP-41010N go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0019033"(viral tegument)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR008648(Herpesvirus transcriptional regulator)|dip:DIP-59209N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/06 2017/08/10 rogid:2cxAL+QkWuplLqfjHqqyO4inHio9606 rogid:KWqdShTimhZpvBff8kaT/qV6Hgw10360 rigid:fnPqYlxUmv4+uJWM0y73lbjByX0 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q07912 uniprotkb:P16749 intact:EBI-603457|intact:EBI-1384159|uniprotkb:Q6ZMQ0|uniprotkb:Q8N6U7|uniprotkb:Q96H59|ensembl:ENSP00000329425 intact:EBI-15832669|uniprotkb:Q7M6M4 psi-mi:ack1_human(display_long)|uniprotkb:ACK1(gene name synonym)|uniprotkb:TNK2(gene name)|psi-mi:TNK2(display_short)|uniprotkb:Tyrosine kinase non-receptor protein 2(gene name synonym) psi-mi:icp27_hcmva(display_long)|uniprotkb:UL69(orf name) psi-mi:"MI:0018"(two hybrid) Aoyagi et al. (2010) pubmed:20133758|doi:10.1073/pnas.0914856107|imex:IM-16247 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10360(hcmva)|taxid:10360("Human cytomegalovirus (strain AD169) (HHV-5)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15832981|imex:IM-16247-17|dip:DIP-187331E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000329425|ensembl:ENST00000439230|ensembl:ENSP00000395588|ensembl:ENST00000671753|ensembl:ENSP00000499858|ensembl:ENSG00000061938(gene)|ensembl:ENST00000333602(transcript)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005095"(GTPase inhibitor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0005912"(adherens junction)|go:"GO:0006897"(endocytosis)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0016310"(phosphorylation)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030154"(cell differentiation)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050699"(WW domain binding)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0070436"(Grb2-EGFR complex)|go:"GO:0097268"(cytoophidium)|go:"GO:0106310"(protein serine kinase activity)|refseq:NP_001010938.1|refseq:NP_005772.3|refseq:NP_001294975.1|dip:DIP-33858N|go:"GO:0106311"|go:"GO:2000369"(regulation of clathrin-dependent endocytosis)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015116(GTPase binding)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR021619|interpro:IPR030220|interpro:IPR036028|interpro:IPR037085|mint:Q07912|rcsb pdb:1CF4|rcsb pdb:1U46|rcsb pdb:1U4D|rcsb pdb:1U54|rcsb pdb:3EQP|rcsb pdb:3EQR|rcsb pdb:4EWH|rcsb pdb:4HZR|rcsb pdb:4HZS|rcsb pdb:4ID7|rcsb pdb:5ZXB|rcsb pdb:6VQM go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0019033"(viral tegument)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR008648(Herpesvirus transcriptional regulator)|dip:DIP-59209N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/06 2017/08/10 rogid:AD7D+7w6zZOL3VHmf23YSk6NW2w9606 rogid:KWqdShTimhZpvBff8kaT/qV6Hgw10360 rigid:yaImEeo4pvL9VJk5/fBk5GCpErk false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9H307 uniprotkb:P16749 intact:EBI-681904|uniprotkb:Q9UQR9|uniprotkb:O60899|uniprotkb:Q53EM7|uniprotkb:Q6P5X4|uniprotkb:Q7KYL1|uniprotkb:Q99738|uniprotkb:Q9UHZ9|uniprotkb:B4DZX8|ensembl:ENSP00000216832 intact:EBI-15832669|uniprotkb:Q7M6M4 psi-mi:pinin_human(display_long)|uniprotkb:140 kDa nuclear and cell adhesion-related phosphoprotein(gene name synonym)|uniprotkb:Domain-rich serine protein(gene name synonym)|uniprotkb:Melanoma metastasis clone A protein(gene name synonym)|uniprotkb:Desmosome-associated protein(gene name synonym)|uniprotkb:SR-like protein(gene name synonym)|uniprotkb:Nuclear protein SDK3(gene name synonym)|uniprotkb:PNN(gene name)|psi-mi:PNN(display_short)|uniprotkb:DRS(gene name synonym)|uniprotkb:MEMA(gene name synonym) psi-mi:icp27_hcmva(display_long)|uniprotkb:UL69(orf name) psi-mi:"MI:0018"(two hybrid) Aoyagi et al. (2010) pubmed:20133758|doi:10.1073/pnas.0914856107|imex:IM-16247 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10360(hcmva)|taxid:10360("Human cytomegalovirus (strain AD169) (HHV-5)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15832964|imex:IM-16247-16|dip:DIP-187321E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002678.2|dip:DIP-32950N|ensembl:ENSG00000100941(gene)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005882"(intermediate filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007155"(cell adhesion)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0030057"(desmosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR006786(Pinin/SDK/memA protein)|interpro:IPR006787(Pinin/SDK)|interpro:IPR039853|mint:Q9H307|ensembl:ENST00000216832(transcript) go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0019033"(viral tegument)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR008648(Herpesvirus transcriptional regulator)|dip:DIP-59209N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/06 2018/04/06 rogid:1pAhD0z8tks+HkWaYWkdMmSjk3s9606 rogid:KWqdShTimhZpvBff8kaT/qV6Hgw10360 rigid:l7oZory1wdAHpxg7E1mxsNJ0QRc false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P60842 uniprotkb:P16749 intact:EBI-73449|uniprotkb:P04765|uniprotkb:Q5U018|uniprotkb:Q61516|uniprotkb:B2R6L8|uniprotkb:D3DTP9|uniprotkb:J3QLC4|ensembl:ENSP00000293831 intact:EBI-15832669|uniprotkb:Q7M6M4 psi-mi:if4a1_human(display_long)|uniprotkb:EIF4A1(gene name)|psi-mi:EIF4A1(display_short)|uniprotkb:EIF4A(gene name synonym)|uniprotkb:DDX2A(gene name synonym)|uniprotkb:ATP-dependent RNA helicase eIF4A-1(gene name synonym) psi-mi:icp27_hcmva(display_long)|uniprotkb:UL69(orf name) psi-mi:"MI:0018"(two hybrid) Aoyagi et al. (2010) pubmed:20133758|doi:10.1073/pnas.0914856107|imex:IM-16247 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10360(hcmva)|taxid:10360("Human cytomegalovirus (strain AD169) (HHV-5)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15832998|imex:IM-16247-18|dip:DIP-187316E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001407.1|refseq:NP_001191439.1|dip:DIP-29755N|ensembl:ENSG00000161960(gene)|ensembl:ENST00000293831(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0002183"(cytoplasmic translational initiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008135"(translation factor activity, RNA binding)|go:"GO:0016020"(membrane)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|interpro:IPR044728|mint:P60842|rcsb pdb:2G9N|rcsb pdb:2ZU6|rcsb pdb:3EIQ|rcsb pdb:5ZBZ|rcsb pdb:5ZC9|rcsb pdb:6ZMW|reactome:R-HSA-1169408|reactome:R-HSA-156827|reactome:R-HSA-429947|reactome:R-HSA-72649|reactome:R-HSA-72662|reactome:R-HSA-72702|reactome:R-HSA-72706 go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0019033"(viral tegument)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR008648(Herpesvirus transcriptional regulator)|dip:DIP-59209N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/06 2017/08/10 rogid:e+2gp47oHrpxFbrBFSM4qTf3r7E9606 rogid:KWqdShTimhZpvBff8kaT/qV6Hgw10360 rigid:UfXjqxaq2ima1RfNE1ZxRgeMTUA false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P39748 uniprotkb:P16749 intact:EBI-707816|ensembl:ENSP00000305480 intact:EBI-15832669|uniprotkb:Q7M6M4 psi-mi:fen1_human(display_long)|uniprotkb:Flap structure-specific endonuclease 1(gene name synonym)|uniprotkb:Maturation factor 1(gene name synonym)|uniprotkb:DNase IV(gene name synonym)|uniprotkb:FEN1(gene name)|psi-mi:FEN1(display_short)|uniprotkb:RAD2(gene name synonym) psi-mi:icp27_hcmva(display_long)|uniprotkb:UL69(orf name) psi-mi:"MI:0018"(two hybrid) Aoyagi et al. (2010) pubmed:20133758|doi:10.1073/pnas.0914856107|imex:IM-16247 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10360(hcmva)|taxid:10360("Human cytomegalovirus (strain AD169) (HHV-5)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15833049|imex:IM-16247-21|dip:DIP-187322E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000168496(gene)|ensembl:ENST00000305885(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0004523"(RNA-DNA hybrid ribonuclease activity)|go:"GO:0004527"(exonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|refseq:NP_004102.1|dip:DIP-24216N|go:"GO:0006287"(base-excision repair, gap-filling)|go:"GO:0006302"(double-strand break repair)|go:"GO:0007613"(memory)|go:"GO:0008309"(double-stranded DNA exodeoxyribonuclease activity)|go:"GO:0008409"(5'-3' exonuclease activity)|go:"GO:0009650"(UV protection)|go:"GO:0016020"(membrane)|go:"GO:0017108"(5'-flap endonuclease activity)|go:"GO:0030145"(manganese ion binding)|go:"GO:0032201"(telomere maintenance via semi-conservative replication)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043137"(DNA replication, removal of RNA primer)|go:"GO:0045876"(positive regulation of sister chromatid cohesion)|go:"GO:0048256"(flap endonuclease activity)|go:"GO:0090305"(nucleic acid phosphodiester bond hydrolysis)|interpro:IPR006084("DNA repair protein (XPGC)/yeast Rad")|interpro:IPR006085(XPG N-terminal)|interpro:IPR006086(XPG I)|interpro:IPR008918(Helix-hairpin-helix motif, class 2)|interpro:IPR019974|interpro:IPR023426|interpro:IPR029060|interpro:IPR036279|mint:P39748|rcsb pdb:1U7B|rcsb pdb:1UL1|rcsb pdb:3Q8K|rcsb pdb:3Q8L|rcsb pdb:3Q8M|rcsb pdb:3UVU|rcsb pdb:5E0V|rcsb pdb:5FV7|rcsb pdb:5K97|rcsb pdb:5KSE|rcsb pdb:5UM9|rcsb pdb:5ZOD|rcsb pdb:5ZOE|rcsb pdb:5ZOF|rcsb pdb:5ZOG|rcsb pdb:6TNZ|reactome:R-HSA-110362|reactome:R-HSA-162594|reactome:R-HSA-174437|reactome:R-HSA-5651801|reactome:R-HSA-5685939|reactome:R-HSA-69166 go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0019033"(viral tegument)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR008648(Herpesvirus transcriptional regulator)|dip:DIP-59209N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/06 2017/08/10 rogid:l9A+/Q39cGBPac0d8USNWE+17NM9606 rogid:KWqdShTimhZpvBff8kaT/qV6Hgw10360 rigid:peh58Ne1FSCeJVN5Id+jVTZiQxY false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P11940 uniprotkb:P16749 intact:EBI-81531|intact:EBI-28983164|ensembl:ENSP00000313007|ensembl:ENSP00000428749|ensembl:ENSP00000428840|ensembl:ENSP00000429119|ensembl:ENSP00000429790|ensembl:ENSP00000429892|ensembl:ENSP00000430012|uniprotkb:Q15097|uniprotkb:Q93004 intact:EBI-15832669|uniprotkb:Q7M6M4 psi-mi:pabp1_human(display_long)|uniprotkb:PABPC1(gene name)|psi-mi:PABPC1(display_short)|uniprotkb:PAB1(gene name synonym)|uniprotkb:PABP1(gene name synonym)|uniprotkb:PABPC2(gene name synonym)|uniprotkb:PABP(gene name synonym) psi-mi:icp27_hcmva(display_long)|uniprotkb:UL69(orf name) psi-mi:"MI:0018"(two hybrid) Aoyagi et al. (2010) pubmed:20133758|doi:10.1073/pnas.0914856107|imex:IM-16247 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10360(hcmva)|taxid:10360("Human cytomegalovirus (strain AD169) (HHV-5)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15833032|imex:IM-16247-20|dip:DIP-187317E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR006515(Polyadenylate binding protein, human types 1, 2, 3, 4)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR036053|mint:P11940|rcsb pdb:1CVJ|rcsb pdb:1G9L|rcsb pdb:1JGN|rcsb pdb:1JH4|rcsb pdb:2K8G|rcsb pdb:2RQG|rcsb pdb:2RQH|rcsb pdb:2X04|rcsb pdb:3KTP|rcsb pdb:3KTR|rcsb pdb:3KUI|rcsb pdb:3KUJ|rcsb pdb:3KUR|rcsb pdb:3KUS|rcsb pdb:3KUT|rcsb pdb:3PKN|interpro:IPR003954(RNA recognition, region 1)|rcsb pdb:3PTH|rcsb pdb:4F02|rcsb pdb:4F25|rcsb pdb:4F26|ensembl:ENSG00000070756(gene)|ensembl:ENST00000318607(transcript)|ensembl:ENST00000520142(transcript)|ensembl:ENST00000520804(transcript)|ensembl:ENST00000521865(transcript)|ensembl:ENST00000522658(transcript)|ensembl:ENST00000522720(transcript)|ensembl:ENST00000523555(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0005634"(nucleus)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031252"(cell leading edge)|go:"GO:0005737"(cytoplasm)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008143"("poly(A) binding")|go:"GO:0048255"(mRNA stabilization)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0008494"(translation activator activity)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000623"(negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002004(Polyadenylate-binding protein/Hyperplastic disc protein)|rcsb pdb:5DX1|refseq:NP_002559.2|rcsb pdb:5DX8|rcsb pdb:5DXA|rcsb pdb:5LGP|rcsb pdb:5LGQ|rcsb pdb:5LGR|rcsb pdb:5LGS|reactome:R-HSA-156827|reactome:R-HSA-429947|reactome:R-HSA-450408|reactome:R-HSA-72649|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|ensembl:ENSP00000313007|ensembl:ENSP00000430012|ensembl:ENSP00000428749|ensembl:ENSP00000429119|ensembl:ENSP00000428840|ensembl:ENSP00000429790|ensembl:ENSP00000429892|refseq:XP_005250918.1|dip:DIP-31613N go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0019033"(viral tegument)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR008648(Herpesvirus transcriptional regulator)|dip:DIP-59209N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/06 2017/08/10 rogid:XudTSPq2h9ckKAc48X88RVafPRU9606 rogid:KWqdShTimhZpvBff8kaT/qV6Hgw10360 rigid:doGeFntudlPwBcOFyaMllIlWu5U false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9Y2B0 uniprotkb:P16749 intact:EBI-1054195|uniprotkb:Q9UHE9|uniprotkb:B2R7B9|ensembl:ENSP00000273308 intact:EBI-15832669|uniprotkb:Q7M6M4 psi-mi:cnpy2_human(display_long)|uniprotkb:TMEM4(gene name synonym)|uniprotkb:MIR-interacting saposin-like protein(gene name synonym)|uniprotkb:Transmembrane protein 4(gene name synonym)|uniprotkb:Putative secreted protein Zsig9(gene name synonym)|uniprotkb:CNPY2(gene name)|psi-mi:CNPY2(display_short)|uniprotkb:MSAP(gene name synonym)|uniprotkb:ZSIG9(gene name synonym)|uniprotkb:UNQ1943/PRO4426(orf name) psi-mi:icp27_hcmva(display_long)|uniprotkb:UL69(orf name) psi-mi:"MI:0018"(two hybrid) Aoyagi et al. (2010) pubmed:20133758|doi:10.1073/pnas.0914856107|imex:IM-16247 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10360(hcmva)|taxid:10360("Human cytomegalovirus (strain AD169) (HHV-5)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15833015|imex:IM-16247-19|dip:DIP-187333E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001177920.1|refseq:NP_055070.1|ensembl:ENSG00000257727(gene)|ensembl:ENST00000273308(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010988"(regulation of low-density lipoprotein particle clearance)|go:"GO:1905599"(positive regulation of low-density lipoprotein receptor activity)|interpro:IPR008139(Saposin B)|interpro:IPR021852|interpro:IPR042415|mint:Q9Y2B0|dip:DIP-50705N go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0019033"(viral tegument)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR008648(Herpesvirus transcriptional regulator)|dip:DIP-59209N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/06 2017/08/10 rogid:m8AFLt3+Fjh99ImqcKladnb00jU9606 rogid:KWqdShTimhZpvBff8kaT/qV6Hgw10360 rigid:nRPbmqZ4nFHnUJ5SHsHHzB+livo false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P43235 uniprotkb:P16749 intact:EBI-715344|ensembl:ENSP00000271651|ensembl:ENSP00000503723|ensembl:ENSP00000504176|uniprotkb:Q6FHS6 intact:EBI-15832669|uniprotkb:Q7M6M4 psi-mi:catk_human(display_long)|uniprotkb:Cathepsin O(gene name synonym)|uniprotkb:Cathepsin X(gene name synonym)|uniprotkb:Cathepsin O2(gene name synonym)|uniprotkb:CTSO(gene name synonym)|uniprotkb:CTSO2(gene name synonym)|uniprotkb:CTSK(gene name)|psi-mi:CTSK(display_short) psi-mi:icp27_hcmva(display_long)|uniprotkb:UL69(orf name) psi-mi:"MI:0018"(two hybrid) Aoyagi et al. (2010) pubmed:20133758|doi:10.1073/pnas.0914856107|imex:IM-16247 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10360(hcmva)|taxid:10360("Human cytomegalovirus (strain AD169) (HHV-5)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15833066|imex:IM-16247-22|dip:DIP-187327E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000387.1|ensembl:ENSG00000143387(gene)|ensembl:ENST00000271651(transcript)|ensembl:ENST00000676824(transcript)|ensembl:ENST00000676966(transcript)|go:"GO:0001957"(intramembranous ossification)|go:"GO:0001968"(fibronectin binding)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005518"(collagen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0006508"(proteolysis)|go:"GO:0006590"(thyroid hormone generation)|go:"GO:0006955"(immune response)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0022617"(extracellular matrix disassembly)|go:"GO:0030574"(collagen catabolic process)|go:"GO:0036021"(endolysosome lumen)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043394"(proteoglycan binding)|go:"GO:0045453"(bone resorption)|go:"GO:0051603"(proteolysis involved in cellular protein catabolic process)|go:"GO:0061037"(negative regulation of cartilage development)|interpro:IPR000169(Peptidase, cysteine peptidase active site)|interpro:IPR000668(Peptidase C1A, papain C-terminal)|interpro:IPR013201(Proteinase inhibitor I29, cathepsin propeptide)|interpro:IPR015644(Peptidase C1A, cathepsin K)|go:"GO:0000422"(autophagy of mitochondrion)|interpro:IPR025660|interpro:IPR025661|interpro:IPR038765|rcsb pdb:1ATK|rcsb pdb:1AU0|interpro:IPR039417|rcsb pdb:1AU2|rcsb pdb:1AU3|rcsb pdb:1AU4|rcsb pdb:1AYU|rcsb pdb:1AYV|rcsb pdb:1AYW|rcsb pdb:1BGO|rcsb pdb:1BY8|rcsb pdb:1MEM|rcsb pdb:1NL6|rcsb pdb:1NLJ|rcsb pdb:1Q6K|rcsb pdb:1SNK|rcsb pdb:1TU6|rcsb pdb:1U9V|rcsb pdb:1U9W|rcsb pdb:1U9X|rcsb pdb:1VSN|rcsb pdb:1YK7|rcsb pdb:1YK8|rcsb pdb:1YT7|rcsb pdb:2ATO|rcsb pdb:2AUX|rcsb pdb:2AUZ|rcsb pdb:2BDL|rcsb pdb:2R6N|rcsb pdb:3C9E|rcsb pdb:3H7D|rcsb pdb:3KW9|rcsb pdb:3KWB|rcsb pdb:3KWZ|rcsb pdb:3KX1|rcsb pdb:3O0U|rcsb pdb:3O1G|rcsb pdb:3OVZ|rcsb pdb:4DMX|rcsb pdb:4DMY|rcsb pdb:4N79|rcsb pdb:4N8W|rcsb pdb:4X6H|rcsb pdb:4X6I|rcsb pdb:4X6J|rcsb pdb:4YV8|rcsb pdb:4YVA|rcsb pdb:5J94|rcsb pdb:5JA7|rcsb pdb:5JH3|rcsb pdb:5TDI|rcsb pdb:5TUN|rcsb pdb:5Z5O|rcsb pdb:6ASH|rcsb pdb:6HGY|rcsb pdb:6PXF|rcsb pdb:6QBS|rcsb pdb:6QL8|rcsb pdb:6QLM|rcsb pdb:6QLW|rcsb pdb:6QLX|rcsb pdb:6QM0|rcsb pdb:7PCK|reactome:R-HSA-1442490|reactome:R-HSA-1474228|reactome:R-HSA-1592389|reactome:R-HSA-1679131|reactome:R-HSA-2132295|reactome:R-HSA-8939242|dip:DIP-39993N go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0019033"(viral tegument)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR008648(Herpesvirus transcriptional regulator)|dip:DIP-59209N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/06 2017/08/10 rogid:C1kQxa3GinFgcXZsDLbrV8bn0FE9606 rogid:KWqdShTimhZpvBff8kaT/qV6Hgw10360 rigid:l4PSsnRv9X3JKCYpGm2RqBrhvOI false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P04406 uniprotkb:P16749 intact:EBI-354056|uniprotkb:P00354|uniprotkb:Q53X65|uniprotkb:E7EUT4|ensembl:ENSP00000229239|ensembl:ENSP00000380068|ensembl:ENSP00000380070 intact:EBI-15832669|uniprotkb:Q7M6M4 psi-mi:g3p_human(display_long)|uniprotkb:GAPDH(gene name)|psi-mi:GAPDH(display_short)|uniprotkb:OK/SW-cl.12(orf name)|uniprotkb:CDABP0047(orf name)|uniprotkb:GAPD(gene name synonym)|uniprotkb:Peptidyl-cysteine S-nitrosylase GAPDH(gene name synonym) psi-mi:icp27_hcmva(display_long)|uniprotkb:UL69(orf name) psi-mi:"MI:0018"(two hybrid) Aoyagi et al. (2010) pubmed:20133758|doi:10.1073/pnas.0914856107|imex:IM-16247 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10360(hcmva)|taxid:10360("Human cytomegalovirus (strain AD169) (HHV-5)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15833083|imex:IM-16247-23|dip:DIP-187332E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002037.2|refseq:NP_001243728.1|refseq:NP_001276674.1|refseq:NP_001276675.1|dip:DIP-32521N|go:"GO:0031965"(nuclear membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0035605"(peptidyl-cysteine S-nitrosylase activity)|go:"GO:0035606"(peptidyl-cysteine S-trans-nitrosylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050661"(NADP binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0050832"(defense response to fungus)|go:"GO:0051287"(NAD binding)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051873"(killing by host of symbiont cells)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0097452"(GAIT complex)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR006424(Glyceraldehyde-3-phosphate dehydrogenase, type I)|interpro:IPR020828|interpro:IPR020829|interpro:IPR020830|interpro:IPR020831|interpro:IPR036291|mint:P04406|rcsb pdb:1U8F|rcsb pdb:1ZNQ|rcsb pdb:2FEH|rcsb pdb:3GPD|rcsb pdb:4WNC|rcsb pdb:4WNI|rcsb pdb:6ADE|rcsb pdb:6M61|rcsb pdb:6YND|rcsb pdb:6YNE|rcsb pdb:6YNF|rcsb pdb:6YNH|reactome:R-HSA-70171|reactome:R-HSA-70263|rcsb pdb:6IQ6|ensembl:ENSG00000111640(gene)|ensembl:ENST00000229239(transcript)|ensembl:ENST00000396859(transcript)|ensembl:ENST00000396861(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0004365"("glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006096"(glycolytic process)|go:"GO:0008017"(microtubule binding)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019828"(aspartic-type endopeptidase inhibitor activity)|go:"GO:0031640"(killing of cells of another organism) go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0019033"(viral tegument)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR008648(Herpesvirus transcriptional regulator)|dip:DIP-59209N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/06 2017/08/10 rogid:9YENN/dfKl/d0tJtfFyQp2o8eAc9606 rogid:KWqdShTimhZpvBff8kaT/qV6Hgw10360 rigid:kv/XmCkPnlkaB3Vnn2YIl89QIQ8 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification)