#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q21227 uniprotkb:Q9NHC3 intact:EBI-2413521|uniprotkb:O62302|ensemblmetazoa:K04G2.8b.1 intact:EBI-6390681|ensemblmetazoa:Y41D4B.13a.1 psi-mi:apr1_caeel(display_long)|uniprotkb:apr-1(gene name)|psi-mi:apr-1(display_short)|uniprotkb:K04G2.8(orf name) psi-mi:ced2_caeel(display_long)|uniprotkb:ced-2(gene name)|psi-mi:ced-2(display_short)|uniprotkb:Cell-corpse engulfment protein CED-2(gene name synonym)|uniprotkb:Y41D4B.13(orf name) psi-mi:"MI:0018"(two hybrid) Cabello et al. (2010) pubmed:20126385|doi:10.1371/journal.pbio.1000297|imex:IM-14668 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15830248|imex:IM-14668-1|dip:DIP-103669E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001021547.1|refseq:NP_492217.2|wormbase:K04G2.8a|wormbase:K04G2.8b|reactome:R-CEL-195253|reactome:R-CEL-3769402|dip:DIP-41257N|reactome:R-CEL-196299|reactome:R-CEL-111465|ensemblmetazoa:K04G2.8b.1(transcript)|ensemblmetazoa:WBGene00000156(gene)|go:"GO:0000003"(reproduction)|go:"GO:0001708"(cell fate specification)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0002119"(nematode larval development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005912"(adherens junction)|go:"GO:0005938"(cell cortex)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007049"(cell cycle)|go:"GO:0007389"(pattern specification process)|go:"GO:0007399"(nervous system development)|go:"GO:0007492"(endoderm development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0015031"(protein transport)|go:"GO:0016342"(catenin complex)|go:"GO:0016476"(regulation of embryonic cell shape)|go:"GO:0016477"(cell migration)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030877"(beta-catenin destruction complex)|go:"GO:0040025"(vulval development)|go:"GO:0040027"(negative regulation of vulval development)|go:"GO:0043652"(engulfment of apoptotic cell)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0051782"(negative regulation of cell division)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026818 ensemblmetazoa:WBGene00000416(gene)|ensemblmetazoa:Y41D4B.13a.1(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0012501"(programmed cell death)|go:"GO:0016477"(cell migration)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0043652"(engulfment of apoptotic cell)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:1901076"(positive regulation of engulfment of apoptotic cell)|go:"GO:1902742"(apoptotic process involved in development)|go:"GO:1903356"(positive regulation of distal tip cell migration)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR036028|interpro:IPR036860|rcsb pdb:3QWX|rcsb pdb:3QWY|reactome:R-CEL-186763|reactome:R-CEL-8875555|reactome:R-CEL-8875656|reactome:R-CEL-8849471|reactome:R-CEL-912631|refseq:NP_500105.1|wormbase:Y41D4B.13a|dip:DIP-25408N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/06 2017/08/10 rogid:3MPRfH/P3BFnIp1q673XvP3KSM06239 rogid:j5cxzcKENbxLxYp0CEUCAXlsmTk6239 rigid:nelnmoJAeYH0UlRPenvvjmr+yXw false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q21227-1 uniprotkb:Q9NHC3 intact:EBI-15830265|ensemblmetazoa:K04G2.8b.1 intact:EBI-6390681|ensemblmetazoa:Y41D4B.13a.1 psi-mi:q21227-1(display_long)|uniprotkb:apr-1(gene name)|psi-mi:apr-1(display_short)|uniprotkb:K04G2.8(orf name) psi-mi:ced2_caeel(display_long)|uniprotkb:ced-2(gene name)|psi-mi:ced-2(display_short)|uniprotkb:Cell-corpse engulfment protein CED-2(gene name synonym)|uniprotkb:Y41D4B.13(orf name) psi-mi:"MI:0018"(two hybrid) Cabello et al. (2010) pubmed:20126385|doi:10.1371/journal.pbio.1000297|imex:IM-14668 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15830273|imex:IM-14668-2|dip:DIP-103669E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2413521(isoform-parent)|ensemblmetazoa:K04G2.8b.1(transcript)|ensemblmetazoa:WBGene00000156(gene) ensemblmetazoa:WBGene00000416(gene)|ensemblmetazoa:Y41D4B.13a.1(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0012501"(programmed cell death)|go:"GO:0016477"(cell migration)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0043652"(engulfment of apoptotic cell)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:1901076"(positive regulation of engulfment of apoptotic cell)|go:"GO:1902742"(apoptotic process involved in development)|go:"GO:1903356"(positive regulation of distal tip cell migration)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR036028|interpro:IPR036860|rcsb pdb:3QWX|rcsb pdb:3QWY|reactome:R-CEL-186763|reactome:R-CEL-8875555|reactome:R-CEL-8875656|reactome:R-CEL-8849471|reactome:R-CEL-912631|refseq:NP_500105.1|wormbase:Y41D4B.13a|dip:DIP-25408N psi-mi:"MI:0465"(dip) isoform-comment:No experimental confirmation available. - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/06 2017/08/10 rogid:3MPRfH/P3BFnIp1q673XvP3KSM06239 rogid:j5cxzcKENbxLxYp0CEUCAXlsmTk6239 rigid:nelnmoJAeYH0UlRPenvvjmr+yXw false binding-associated region:1-545|mutation decreasing interaction:489-489 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)