#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P22216	uniprotkb:P14737	intact:EBI-17843|uniprotkb:D6W3L5|uniprotkb:Q6B1S1|ensemblfungi:YPL153C	intact:EBI-14788|ensemblfungi:YDR217C|uniprotkb:Q04920|uniprotkb:D6VSK0	psi-mi:rad53_yeast(display_long)|uniprotkb:RAD53(gene name)|psi-mi:RAD53(display_short)|uniprotkb:MEC2(gene name synonym)|uniprotkb:SAD1(gene name synonym)|uniprotkb:Serine-protein kinase 1(gene name synonym)|uniprotkb:SPK1(gene name synonym)|uniprotkb:P2588(orf name)|uniprotkb:YPL153C(locus name)|uniprotkb:CHEK2 homolog(gene name synonym)	psi-mi:rad9_yeast(display_long)|uniprotkb:YD9934.02C(orf name)|uniprotkb:YDR217C(locus name)|uniprotkb:RAD9(gene name)|psi-mi:RAD9(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Vidanes et al. (2010)	pubmed:20126259|doi:10.1371/journal.pbio.1000286|imex:IM-14666	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15829983|imex:IM-14666-2|dip:DIP-3202E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015172.1|sgd:S000006074|ensemblfungi:YPL153C(gene)|ensemblfungi:YPL153C_mRNA(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006281"(DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0008104"(protein localization)|go:"GO:0009202"(deoxyribonucleoside triphosphate biosynthetic process)|go:"GO:0042326"(negative regulation of phosphorylation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901857"(positive regulation of cellular respiration)|interpro:IPR000253(Forkhead-associated)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016256(Serine/threonine-protein kinase RAD53)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:1DMZ|rcsb pdb:1FHQ|rcsb pdb:1FHR|rcsb pdb:1G3G|rcsb pdb:1G6G|rcsb pdb:1J4K|rcsb pdb:1J4L|rcsb pdb:1J4O|rcsb pdb:1J4P|rcsb pdb:1J4Q|rcsb pdb:1K2M|rcsb pdb:1K2N|rcsb pdb:1K3J|rcsb pdb:1K3N|rcsb pdb:1K3Q|rcsb pdb:1QU5|rcsb pdb:2A0T|rcsb pdb:2JQI|rcsb pdb:2JQL|rcsb pdb:2YGV|rcsb pdb:4PDP|rcsb pdb:4PDS|rcsb pdb:5T2F|rcsb pdb:5T2S|rcsb pdb:5XZV|rcsb pdb:5XZW|rcsb pdb:6C4U|dip:DIP-2322N|mint:P22216	ensemblfungi:YDR217C(gene)|ensemblfungi:YDR217C_mRNA(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000785"(chromatin)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|interpro:IPR036420|rcsb pdb:1FHR|rcsb pdb:1J4K|go:"GO:0006281"(DNA repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006302"(double-strand break repair)|rcsb pdb:1J4L|go:"GO:0008047"(enzyme activator activity)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0042393"(histone binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0110027"(negative regulation of DNA strand resection involved in replication fork processing)|interpro:IPR001357(BRCT)|interpro:IPR013914(Rad9-like Rad53-binding, fungi)|refseq:NP_010503.1|sgd:S000002625|rcsb pdb:1K2N|rcsb pdb:1K3N|rcsb pdb:1J4P|rcsb pdb:1J4Q|rcsb pdb:1K2M|rcsb pdb:1K3Q|rcsb pdb:2FF4|reactome:R-SCE-3232118|dip:DIP-2516N|mint:P14737	psi-mi:"MI:0465"(dip)	crc64:84A9612229CA72D1	crc64:FCDAC16694484D8D	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/08/06	2017/08/10	rogid:OU8gjvSvTtvDvk+en1y8hyEjFhI559292	rogid:QP2yNFtW+I5evjdBEW3r5EPLHLU559292	rigid:lvX0Jg3N2XzoVsfBxpDwxSvc2dI	false	-	flag tag:c-c	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P22216	uniprotkb:P32562	intact:EBI-17843|uniprotkb:D6W3L5|uniprotkb:Q6B1S1|ensemblfungi:YPL153C	intact:EBI-4440|ensemblfungi:YMR001C|uniprotkb:D6VZH5	psi-mi:rad53_yeast(display_long)|uniprotkb:RAD53(gene name)|psi-mi:RAD53(display_short)|uniprotkb:MEC2(gene name synonym)|uniprotkb:SAD1(gene name synonym)|uniprotkb:Serine-protein kinase 1(gene name synonym)|uniprotkb:SPK1(gene name synonym)|uniprotkb:P2588(orf name)|uniprotkb:YPL153C(locus name)|uniprotkb:CHEK2 homolog(gene name synonym)	psi-mi:cdc5_yeast(display_long)|uniprotkb:CDC5(gene name)|psi-mi:CDC5(display_short)|uniprotkb:MSD2(gene name synonym)|uniprotkb:PKX2(gene name synonym)|uniprotkb:YMR001C(locus name)|uniprotkb:YM8270.03C(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Vidanes et al. (2010)	pubmed:20126259|doi:10.1371/journal.pbio.1000286|imex:IM-14666	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15829964|imex:IM-14666-1|dip:DIP-103665E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015172.1|sgd:S000006074|ensemblfungi:YPL153C(gene)|ensemblfungi:YPL153C_mRNA(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006281"(DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0008104"(protein localization)|go:"GO:0009202"(deoxyribonucleoside triphosphate biosynthetic process)|go:"GO:0042326"(negative regulation of phosphorylation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901857"(positive regulation of cellular respiration)|interpro:IPR000253(Forkhead-associated)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016256(Serine/threonine-protein kinase RAD53)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:1DMZ|rcsb pdb:1FHQ|rcsb pdb:1FHR|rcsb pdb:1G3G|rcsb pdb:1G6G|rcsb pdb:1J4K|rcsb pdb:1J4L|rcsb pdb:1J4O|rcsb pdb:1J4P|rcsb pdb:1J4Q|rcsb pdb:1K2M|rcsb pdb:1K2N|rcsb pdb:1K3J|rcsb pdb:1K3N|rcsb pdb:1K3Q|rcsb pdb:1QU5|rcsb pdb:2A0T|rcsb pdb:2JQI|rcsb pdb:2JQL|rcsb pdb:2YGV|rcsb pdb:4PDP|rcsb pdb:4PDS|rcsb pdb:5T2F|rcsb pdb:5T2S|rcsb pdb:5XZV|rcsb pdb:5XZW|rcsb pdb:6C4U|dip:DIP-2322N|mint:P22216	ensemblfungi:YMR001C(gene)|ensemblfungi:YMR001C_mRNA(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0000922"(spindle pole)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0010458"(exit from mitosis)|go:"GO:0010696"(positive regulation of mitotic spindle pole body separation)|go:"GO:0019237"(centromeric DNA binding)|refseq:NP_013714.1|sgd:S000004603|reactome:R-SCE-6804115|reactome:R-SCE-156711|reactome:R-SCE-162658|reactome:R-SCE-2565942|dip:DIP-2321N|reactome:R-SCE-2500257|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0035025"(positive regulation of Rho protein signal transduction)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051301"(cell division)|go:"GO:0070194"(synaptonemal complex disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0110083"(positive regulation of protein localization to cell division site involved in mitotic actomyosin contractile ring assembly)|go:"GO:1902542"(regulation of protein localization to mitotic spindle pole body)|go:"GO:1903353"(regulation of nucleus organization)|go:"GO:1904750"(negative regulation of protein localization to nucleolus)|go:"GO:1905339"(positive regulation of cohesin unloading)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033695|interpro:IPR033701|interpro:IPR036947|rcsb pdb:6MF4|rcsb pdb:6MF5|rcsb pdb:6MF6	psi-mi:"MI:0465"(dip)	crc64:84A9612229CA72D1	crc64:B5A25F1BBBEAA3DC	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/08/06	2017/08/10	rogid:OU8gjvSvTtvDvk+en1y8hyEjFhI559292	rogid:XXSkltYvBA9Zkh0Kr5s1znazUC0559292	rigid:1s0e7a0sa8O8BgXwFncqg7Nvpqc	false	-	ha tag:n-n	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P32562	uniprotkb:P14737	intact:EBI-4440|ensemblfungi:YMR001C|uniprotkb:D6VZH5	intact:EBI-14788|ensemblfungi:YDR217C|uniprotkb:Q04920|uniprotkb:D6VSK0	psi-mi:cdc5_yeast(display_long)|uniprotkb:CDC5(gene name)|psi-mi:CDC5(display_short)|uniprotkb:MSD2(gene name synonym)|uniprotkb:PKX2(gene name synonym)|uniprotkb:YMR001C(locus name)|uniprotkb:YM8270.03C(orf name)	psi-mi:rad9_yeast(display_long)|uniprotkb:YD9934.02C(orf name)|uniprotkb:YDR217C(locus name)|uniprotkb:RAD9(gene name)|psi-mi:RAD9(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Vidanes et al. (2010)	pubmed:20126259|doi:10.1371/journal.pbio.1000286|imex:IM-14666	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15830002|imex:IM-14666-3|dip:DIP-103664E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YMR001C(gene)|ensemblfungi:YMR001C_mRNA(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0000922"(spindle pole)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0010458"(exit from mitosis)|go:"GO:0010696"(positive regulation of mitotic spindle pole body separation)|go:"GO:0019237"(centromeric DNA binding)|refseq:NP_013714.1|sgd:S000004603|reactome:R-SCE-6804115|reactome:R-SCE-156711|reactome:R-SCE-162658|reactome:R-SCE-2565942|dip:DIP-2321N|reactome:R-SCE-2500257|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0035025"(positive regulation of Rho protein signal transduction)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051301"(cell division)|go:"GO:0070194"(synaptonemal complex disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0110083"(positive regulation of protein localization to cell division site involved in mitotic actomyosin contractile ring assembly)|go:"GO:1902542"(regulation of protein localization to mitotic spindle pole body)|go:"GO:1903353"(regulation of nucleus organization)|go:"GO:1904750"(negative regulation of protein localization to nucleolus)|go:"GO:1905339"(positive regulation of cohesin unloading)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033695|interpro:IPR033701|interpro:IPR036947|rcsb pdb:6MF4|rcsb pdb:6MF5|rcsb pdb:6MF6	ensemblfungi:YDR217C(gene)|ensemblfungi:YDR217C_mRNA(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000785"(chromatin)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|interpro:IPR036420|rcsb pdb:1FHR|rcsb pdb:1J4K|go:"GO:0006281"(DNA repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006302"(double-strand break repair)|rcsb pdb:1J4L|go:"GO:0008047"(enzyme activator activity)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0042393"(histone binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0110027"(negative regulation of DNA strand resection involved in replication fork processing)|interpro:IPR001357(BRCT)|interpro:IPR013914(Rad9-like Rad53-binding, fungi)|refseq:NP_010503.1|sgd:S000002625|rcsb pdb:1K2N|rcsb pdb:1K3N|rcsb pdb:1J4P|rcsb pdb:1J4Q|rcsb pdb:1K2M|rcsb pdb:1K3Q|rcsb pdb:2FF4|reactome:R-SCE-3232118|dip:DIP-2516N|mint:P14737	psi-mi:"MI:0465"(dip)	crc64:B5A25F1BBBEAA3DC	crc64:FCDAC16694484D8D	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/08/06	2017/08/10	rogid:XXSkltYvBA9Zkh0Kr5s1znazUC0559292	rogid:QP2yNFtW+I5evjdBEW3r5EPLHLU559292	rigid:tUItyJq1dJjGf8SamyQpZF7sCRc	false	ha tag:n-n	flag tag:c-c	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P22216	uniprotkb:P32562	intact:EBI-17843|uniprotkb:D6W3L5|uniprotkb:Q6B1S1|ensemblfungi:YPL153C	intact:EBI-4440|ensemblfungi:YMR001C|uniprotkb:D6VZH5	psi-mi:rad53_yeast(display_long)|uniprotkb:RAD53(gene name)|psi-mi:RAD53(display_short)|uniprotkb:MEC2(gene name synonym)|uniprotkb:SAD1(gene name synonym)|uniprotkb:Serine-protein kinase 1(gene name synonym)|uniprotkb:SPK1(gene name synonym)|uniprotkb:P2588(orf name)|uniprotkb:YPL153C(locus name)|uniprotkb:CHEK2 homolog(gene name synonym)	psi-mi:cdc5_yeast(display_long)|uniprotkb:CDC5(gene name)|psi-mi:CDC5(display_short)|uniprotkb:MSD2(gene name synonym)|uniprotkb:PKX2(gene name synonym)|uniprotkb:YMR001C(locus name)|uniprotkb:YM8270.03C(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Vidanes et al. (2010)	pubmed:20126259|doi:10.1371/journal.pbio.1000286|imex:IM-14666	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15830047|imex:IM-14666-5|dip:DIP-103665E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015172.1|sgd:S000006074|ensemblfungi:YPL153C(gene)|ensemblfungi:YPL153C_mRNA(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006281"(DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0008104"(protein localization)|go:"GO:0009202"(deoxyribonucleoside triphosphate biosynthetic process)|go:"GO:0042326"(negative regulation of phosphorylation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901857"(positive regulation of cellular respiration)|interpro:IPR000253(Forkhead-associated)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016256(Serine/threonine-protein kinase RAD53)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:1DMZ|rcsb pdb:1FHQ|rcsb pdb:1FHR|rcsb pdb:1G3G|rcsb pdb:1G6G|rcsb pdb:1J4K|rcsb pdb:1J4L|rcsb pdb:1J4O|rcsb pdb:1J4P|rcsb pdb:1J4Q|rcsb pdb:1K2M|rcsb pdb:1K2N|rcsb pdb:1K3J|rcsb pdb:1K3N|rcsb pdb:1K3Q|rcsb pdb:1QU5|rcsb pdb:2A0T|rcsb pdb:2JQI|rcsb pdb:2JQL|rcsb pdb:2YGV|rcsb pdb:4PDP|rcsb pdb:4PDS|rcsb pdb:5T2F|rcsb pdb:5T2S|rcsb pdb:5XZV|rcsb pdb:5XZW|rcsb pdb:6C4U|dip:DIP-2322N|mint:P22216	ensemblfungi:YMR001C(gene)|ensemblfungi:YMR001C_mRNA(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0000922"(spindle pole)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0010458"(exit from mitosis)|go:"GO:0010696"(positive regulation of mitotic spindle pole body separation)|go:"GO:0019237"(centromeric DNA binding)|refseq:NP_013714.1|sgd:S000004603|reactome:R-SCE-6804115|reactome:R-SCE-156711|reactome:R-SCE-162658|reactome:R-SCE-2565942|dip:DIP-2321N|reactome:R-SCE-2500257|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0035025"(positive regulation of Rho protein signal transduction)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051301"(cell division)|go:"GO:0070194"(synaptonemal complex disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0110083"(positive regulation of protein localization to cell division site involved in mitotic actomyosin contractile ring assembly)|go:"GO:1902542"(regulation of protein localization to mitotic spindle pole body)|go:"GO:1903353"(regulation of nucleus organization)|go:"GO:1904750"(negative regulation of protein localization to nucleolus)|go:"GO:1905339"(positive regulation of cohesin unloading)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033695|interpro:IPR033701|interpro:IPR036947|rcsb pdb:6MF4|rcsb pdb:6MF5|rcsb pdb:6MF6	psi-mi:"MI:0465"(dip)	crc64:84A9612229CA72D1	crc64:B5A25F1BBBEAA3DC	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/08/06	2017/08/10	rogid:OU8gjvSvTtvDvk+en1y8hyEjFhI559292	rogid:XXSkltYvBA9Zkh0Kr5s1znazUC0559292	rigid:1s0e7a0sa8O8BgXwFncqg7Nvpqc	false	-	ha tag:n-n	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P14737	uniprotkb:P32562	intact:EBI-14788|ensemblfungi:YDR217C|uniprotkb:Q04920|uniprotkb:D6VSK0	intact:EBI-4440|ensemblfungi:YMR001C|uniprotkb:D6VZH5	psi-mi:rad9_yeast(display_long)|uniprotkb:YD9934.02C(orf name)|uniprotkb:YDR217C(locus name)|uniprotkb:RAD9(gene name)|psi-mi:RAD9(display_short)	psi-mi:cdc5_yeast(display_long)|uniprotkb:CDC5(gene name)|psi-mi:CDC5(display_short)|uniprotkb:MSD2(gene name synonym)|uniprotkb:PKX2(gene name synonym)|uniprotkb:YMR001C(locus name)|uniprotkb:YM8270.03C(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Vidanes et al. (2010)	pubmed:20126259|doi:10.1371/journal.pbio.1000286|imex:IM-14666	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15830023|imex:IM-14666-4|dip:DIP-103664E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YDR217C(gene)|ensemblfungi:YDR217C_mRNA(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000785"(chromatin)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|interpro:IPR036420|rcsb pdb:1FHR|rcsb pdb:1J4K|go:"GO:0006281"(DNA repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006302"(double-strand break repair)|rcsb pdb:1J4L|go:"GO:0008047"(enzyme activator activity)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0042393"(histone binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0110027"(negative regulation of DNA strand resection involved in replication fork processing)|interpro:IPR001357(BRCT)|interpro:IPR013914(Rad9-like Rad53-binding, fungi)|refseq:NP_010503.1|sgd:S000002625|rcsb pdb:1K2N|rcsb pdb:1K3N|rcsb pdb:1J4P|rcsb pdb:1J4Q|rcsb pdb:1K2M|rcsb pdb:1K3Q|rcsb pdb:2FF4|reactome:R-SCE-3232118|dip:DIP-2516N|mint:P14737	ensemblfungi:YMR001C(gene)|ensemblfungi:YMR001C_mRNA(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0000922"(spindle pole)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0010458"(exit from mitosis)|go:"GO:0010696"(positive regulation of mitotic spindle pole body separation)|go:"GO:0019237"(centromeric DNA binding)|refseq:NP_013714.1|sgd:S000004603|reactome:R-SCE-6804115|reactome:R-SCE-156711|reactome:R-SCE-162658|reactome:R-SCE-2565942|dip:DIP-2321N|reactome:R-SCE-2500257|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0035025"(positive regulation of Rho protein signal transduction)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051301"(cell division)|go:"GO:0070194"(synaptonemal complex disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0110083"(positive regulation of protein localization to cell division site involved in mitotic actomyosin contractile ring assembly)|go:"GO:1902542"(regulation of protein localization to mitotic spindle pole body)|go:"GO:1903353"(regulation of nucleus organization)|go:"GO:1904750"(negative regulation of protein localization to nucleolus)|go:"GO:1905339"(positive regulation of cohesin unloading)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033695|interpro:IPR033701|interpro:IPR036947|rcsb pdb:6MF4|rcsb pdb:6MF5|rcsb pdb:6MF6	psi-mi:"MI:0465"(dip)	crc64:FCDAC16694484D8D	crc64:B5A25F1BBBEAA3DC	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/08/06	2017/08/10	rogid:QP2yNFtW+I5evjdBEW3r5EPLHLU559292	rogid:XXSkltYvBA9Zkh0Kr5s1znazUC0559292	rigid:tUItyJq1dJjGf8SamyQpZF7sCRc	false	flag tag:c-c	ha tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P14737	uniprotkb:P14737	intact:EBI-14788|ensemblfungi:YDR217C|uniprotkb:Q04920|uniprotkb:D6VSK0	intact:EBI-14788|ensemblfungi:YDR217C|uniprotkb:Q04920|uniprotkb:D6VSK0	psi-mi:rad9_yeast(display_long)|uniprotkb:YD9934.02C(orf name)|uniprotkb:YDR217C(locus name)|uniprotkb:RAD9(gene name)|psi-mi:RAD9(display_short)	psi-mi:rad9_yeast(display_long)|uniprotkb:YD9934.02C(orf name)|uniprotkb:YDR217C(locus name)|uniprotkb:RAD9(gene name)|psi-mi:RAD9(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Vidanes et al. (2010)	pubmed:20126259|doi:10.1371/journal.pbio.1000286|imex:IM-14666	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15830023|imex:IM-14666-4|dip:DIP-103664E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YDR217C(gene)|ensemblfungi:YDR217C_mRNA(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000785"(chromatin)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|interpro:IPR036420|rcsb pdb:1FHR|rcsb pdb:1J4K|go:"GO:0006281"(DNA repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006302"(double-strand break repair)|rcsb pdb:1J4L|go:"GO:0008047"(enzyme activator activity)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0042393"(histone binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0110027"(negative regulation of DNA strand resection involved in replication fork processing)|interpro:IPR001357(BRCT)|interpro:IPR013914(Rad9-like Rad53-binding, fungi)|refseq:NP_010503.1|sgd:S000002625|rcsb pdb:1K2N|rcsb pdb:1K3N|rcsb pdb:1J4P|rcsb pdb:1J4Q|rcsb pdb:1K2M|rcsb pdb:1K3Q|rcsb pdb:2FF4|reactome:R-SCE-3232118|dip:DIP-2516N|mint:P14737	ensemblfungi:YDR217C(gene)|ensemblfungi:YDR217C_mRNA(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000785"(chromatin)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|interpro:IPR036420|rcsb pdb:1FHR|rcsb pdb:1J4K|go:"GO:0006281"(DNA repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006302"(double-strand break repair)|rcsb pdb:1J4L|go:"GO:0008047"(enzyme activator activity)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0042393"(histone binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0110027"(negative regulation of DNA strand resection involved in replication fork processing)|interpro:IPR001357(BRCT)|interpro:IPR013914(Rad9-like Rad53-binding, fungi)|refseq:NP_010503.1|sgd:S000002625|rcsb pdb:1K2N|rcsb pdb:1K3N|rcsb pdb:1J4P|rcsb pdb:1J4Q|rcsb pdb:1K2M|rcsb pdb:1K3Q|rcsb pdb:2FF4|reactome:R-SCE-3232118|dip:DIP-2516N|mint:P14737	psi-mi:"MI:0465"(dip)	crc64:FCDAC16694484D8D	crc64:FCDAC16694484D8D	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/08/06	2017/08/10	rogid:QP2yNFtW+I5evjdBEW3r5EPLHLU559292	rogid:QP2yNFtW+I5evjdBEW3r5EPLHLU559292	rigid:tUItyJq1dJjGf8SamyQpZF7sCRc	false	flag tag:c-c	myc tag:c-c	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P22216	uniprotkb:P32562	intact:EBI-17843|uniprotkb:D6W3L5|uniprotkb:Q6B1S1|ensemblfungi:YPL153C	intact:EBI-4440|ensemblfungi:YMR001C|uniprotkb:D6VZH5	psi-mi:rad53_yeast(display_long)|uniprotkb:RAD53(gene name)|psi-mi:RAD53(display_short)|uniprotkb:MEC2(gene name synonym)|uniprotkb:SAD1(gene name synonym)|uniprotkb:Serine-protein kinase 1(gene name synonym)|uniprotkb:SPK1(gene name synonym)|uniprotkb:P2588(orf name)|uniprotkb:YPL153C(locus name)|uniprotkb:CHEK2 homolog(gene name synonym)	psi-mi:cdc5_yeast(display_long)|uniprotkb:CDC5(gene name)|psi-mi:CDC5(display_short)|uniprotkb:MSD2(gene name synonym)|uniprotkb:PKX2(gene name synonym)|uniprotkb:YMR001C(locus name)|uniprotkb:YM8270.03C(orf name)	psi-mi:"MI:0424"(protein kinase assay)	Vidanes et al. (2010)	pubmed:20126259|doi:10.1371/journal.pbio.1000286|imex:IM-14666	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15830066|imex:IM-14666-6|dip:DIP-103665E	-	-	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015172.1|sgd:S000006074|ensemblfungi:YPL153C(gene)|ensemblfungi:YPL153C_mRNA(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006281"(DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0008104"(protein localization)|go:"GO:0009202"(deoxyribonucleoside triphosphate biosynthetic process)|go:"GO:0042326"(negative regulation of phosphorylation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901857"(positive regulation of cellular respiration)|interpro:IPR000253(Forkhead-associated)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016256(Serine/threonine-protein kinase RAD53)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:1DMZ|rcsb pdb:1FHQ|rcsb pdb:1FHR|rcsb pdb:1G3G|rcsb pdb:1G6G|rcsb pdb:1J4K|rcsb pdb:1J4L|rcsb pdb:1J4O|rcsb pdb:1J4P|rcsb pdb:1J4Q|rcsb pdb:1K2M|rcsb pdb:1K2N|rcsb pdb:1K3J|rcsb pdb:1K3N|rcsb pdb:1K3Q|rcsb pdb:1QU5|rcsb pdb:2A0T|rcsb pdb:2JQI|rcsb pdb:2JQL|rcsb pdb:2YGV|rcsb pdb:4PDP|rcsb pdb:4PDS|rcsb pdb:5T2F|rcsb pdb:5T2S|rcsb pdb:5XZV|rcsb pdb:5XZW|rcsb pdb:6C4U|dip:DIP-2322N|mint:P22216	ensemblfungi:YMR001C(gene)|ensemblfungi:YMR001C_mRNA(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0000922"(spindle pole)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0010458"(exit from mitosis)|go:"GO:0010696"(positive regulation of mitotic spindle pole body separation)|go:"GO:0019237"(centromeric DNA binding)|refseq:NP_013714.1|sgd:S000004603|reactome:R-SCE-6804115|reactome:R-SCE-156711|reactome:R-SCE-162658|reactome:R-SCE-2565942|dip:DIP-2321N|reactome:R-SCE-2500257|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0035025"(positive regulation of Rho protein signal transduction)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051301"(cell division)|go:"GO:0070194"(synaptonemal complex disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0110083"(positive regulation of protein localization to cell division site involved in mitotic actomyosin contractile ring assembly)|go:"GO:1902542"(regulation of protein localization to mitotic spindle pole body)|go:"GO:1903353"(regulation of nucleus organization)|go:"GO:1904750"(negative regulation of protein localization to nucleolus)|go:"GO:1905339"(positive regulation of cohesin unloading)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033695|interpro:IPR033701|interpro:IPR036947|rcsb pdb:6MF4|rcsb pdb:6MF5|rcsb pdb:6MF6	psi-mi:"MI:0465"(dip)	crc64:84A9612229CA72D1	crc64:B5A25F1BBBEAA3DC	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/06	2017/08/10	rogid:OU8gjvSvTtvDvk+en1y8hyEjFhI559292	rogid:XXSkltYvBA9Zkh0Kr5s1znazUC0559292	rigid:1s0e7a0sa8O8BgXwFncqg7Nvpqc	false	mutation disrupting interaction:70-70,605-605	-	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)