#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q03834 uniprotkb:P14242 intact:EBI-11383|ensemblfungi:YDR097C|uniprotkb:D6VS82 intact:EBI-13561|uniprotkb:Q2I044|uniprotkb:Q2I045|uniprotkb:Q45TY4|uniprotkb:Q8TG48|uniprotkb:Q8TG50|uniprotkb:Q8TG54|uniprotkb:Q8TG57|uniprotkb:D6W197|ensemblfungi:YNL082W psi-mi:msh6_yeast(display_long)|uniprotkb:MSH6(gene name)|psi-mi:MSH6(display_short)|uniprotkb:YDR097C(locus name)|uniprotkb:YD8557.04C(orf name)|uniprotkb:PMS3(gene name synonym)|uniprotkb:MutS protein homolog 6(gene name synonym)|uniprotkb:Postmeiotic segregation protein 3(gene name synonym) psi-mi:pms1_yeast(display_long)|uniprotkb:PMS1(gene name)|psi-mi:PMS1(display_short)|uniprotkb:YNL082W(locus name)|uniprotkb:N2317(orf name)|uniprotkb:Postmeiotic segregation protein 1(gene name synonym) psi-mi:"MI:0096"(pull down) Mendillo et al. (2009) pubmed:20080788|doi:10.1073/pnas.0912250106|imex:IM-15246 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15828746|imex:IM-15246-2|dip:DIP-185758E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YDR097C(gene)|go:"GO:0030983"(mismatched DNA binding)|go:"GO:0032300"(mismatch repair complex)|go:"GO:0032301"(MutSalpha complex)|go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0043111"(replication fork arrest)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0045910"(negative regulation of DNA recombination)|interpro:IPR000432(DNA mismatch repair protein MutS, C-terminal)|interpro:IPR007695(DNA mismatch repair protein MutS-like, N-terminal)|interpro:IPR007696(DNA mismatch repair protein MutS, core)|interpro:IPR007860(DNA mismatch repair protein MutS, connector)|ensemblfungi:YDR097C_mRNA(transcript)|go:"GO:0000400"(four-way junction DNA binding)|go:"GO:0000710"(meiotic mismatch repair)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|interpro:IPR007861(DNA mismatch repair protein MutS, clamp)|go:"GO:0005737"(cytoplasm)|go:"GO:0006290"(pyrimidine dimer repair)|go:"GO:0006298"(mismatch repair)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0016887"(ATP hydrolysis activity)|interpro:IPR016151(DNA mismatch repair protein MutS, N-terminal)|interpro:IPR017261(DNA mismatch repair protein Msh6)|interpro:IPR027417|interpro:IPR036187|interpro:IPR036678|reactome:R-SCE-5358565|refseq:NP_010382.3|sgd:S000002504|mint:Q03834|dip:DIP-2423N sgd:S000005026|refseq:NP_014317.4|ensemblfungi:YNL082W(gene)|ensemblfungi:YNL082W_mRNA(transcript)|go:"GO:0000710"(meiotic mismatch repair)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006298"(mismatch repair)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0030983"(mismatched DNA binding)|go:"GO:0032300"(mismatch repair complex)|go:"GO:0032389"(MutLalpha complex)|interpro:IPR002099(DNA mismatch repair protein)|interpro:IPR013507(DNA mismatch repair protein, C-terminal)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR014762(DNA mismatch repair, conserved site)|interpro:IPR014790(MutL, C-terminal, dimerisation)|interpro:IPR020568|interpro:IPR036890|interpro:IPR037198|interpro:IPR038973|interpro:IPR042121|rcsb pdb:3H4L|rcsb pdb:4E4W|rcsb pdb:4FMN|rcsb pdb:4FMO|reactome:R-SCE-5358565|mint:P14242|dip:DIP-2416N psi-mi:"MI:0465"(dip) crc64:11A6883AADCFA222 crc64:2E0FFBC59B718854 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/06 2017/08/10 rogid:IufLo1sfhfBnNLFLGR/VO5gkApI559292 rogid:JMHy1ud9pY728nqxAv82qHJ6eZk559292 rigid:v14dH97+vueuu0y3YIPBXOt2Ehg false binding-associated region:420-613|maltose binding protein tag:n-n flag tag:c-c - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P23367 uniprotkb:P23909 intact:EBI-554913|uniprotkb:Q2M6D5|ensemblbacteria:AAC77127|ensemblbacteria:BAE78171 intact:EBI-554920|uniprotkb:P71279|uniprotkb:Q2MA96|ensemblbacteria:AAC75775|ensemblbacteria:BAE76810 psi-mi:mutl_ecoli(display_long)|uniprotkb:mutL(gene name)|psi-mi:mutL(display_short)|uniprotkb:b4170(locus name)|uniprotkb:JW4128(locus name) psi-mi:muts_ecoli(display_long)|uniprotkb:mutS(gene name)|psi-mi:mutS(display_short)|uniprotkb:fdv(gene name synonym)|uniprotkb:b2733(locus name)|uniprotkb:JW2703(locus name) psi-mi:"MI:0944"(mass spectrometry study of hydrogen/deuterium exchange) Mendillo et al. (2009) pubmed:20080788|doi:10.1073/pnas.0912250106|imex:IM-15246 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15828729|imex:IM-15246-1|dip:DIP-18041E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_418591.1|refseq:WP_001122505.1|dip:DIP-10285N|ensemblbacteria:AAC77127(transcript)|ensemblbacteria:b4170(gene)|ensemblbacteria:BAE78171(gene)|ensemblbacteria:BAE78171(transcript)|go:"GO:0000018"(regulation of DNA recombination)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0006298"(mismatch repair)|go:"GO:0030983"(mismatched DNA binding)|go:"GO:0032300"(mismatch repair complex)|go:"GO:0042802"(identical protein binding)|interpro:IPR002099(DNA mismatch repair protein)|interpro:IPR013507(DNA mismatch repair protein, C-terminal)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR014762(DNA mismatch repair, conserved site)|interpro:IPR014790(MutL, C-terminal, dimerisation)|interpro:IPR020568|interpro:IPR020667|interpro:IPR036890|interpro:IPR037198|interpro:IPR038973|interpro:IPR042120|interpro:IPR042121|rcsb pdb:1B62|rcsb pdb:1B63|rcsb pdb:1BKN|rcsb pdb:1NHH|rcsb pdb:1NHI|rcsb pdb:1NHJ|rcsb pdb:1X9Z|rcsb pdb:5AKB|rcsb pdb:5AKC|rcsb pdb:5AKD|rcsb pdb:6E8E|rcsb pdb:7AIB|rcsb pdb:7AIC refseq:NP_417213.1|refseq:WP_001272928.1|dip:DIP-10287N|ensemblbacteria:AAC75775(transcript)|ensemblbacteria:b2733(gene)|ensemblbacteria:BAE76810(gene)|ensemblbacteria:BAE76810(transcript)|go:"GO:0000018"(regulation of DNA recombination)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006298"(mismatch repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0030983"(mismatched DNA binding)|go:"GO:0032136"(adenine/cytosine mispair binding)|go:"GO:0032300"(mismatch repair complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043531"(ADP binding)|interpro:IPR000432(DNA mismatch repair protein MutS, C-terminal)|interpro:IPR005748(DNA mismatch repair protein MutS, type 1)|interpro:IPR007695(DNA mismatch repair protein MutS-like, N-terminal)|interpro:IPR007696(DNA mismatch repair protein MutS, core)|interpro:IPR007860(DNA mismatch repair protein MutS, connector)|interpro:IPR007861(DNA mismatch repair protein MutS, clamp)|interpro:IPR016151(DNA mismatch repair protein MutS, N-terminal)|interpro:IPR017261(DNA mismatch repair protein Msh6)|interpro:IPR027417|interpro:IPR036187|interpro:IPR036678|rcsb pdb:1E3M|rcsb pdb:1NG9|rcsb pdb:1OH5|rcsb pdb:1OH6|rcsb pdb:1OH7|rcsb pdb:1OH8|rcsb pdb:1W7A|rcsb pdb:1WB9|rcsb pdb:1WBB|rcsb pdb:1WBD|rcsb pdb:2OK2|rcsb pdb:2WTU|rcsb pdb:3K0S|rcsb pdb:3ZLJ|rcsb pdb:5AKB|rcsb pdb:5AKC|rcsb pdb:5AKD|rcsb pdb:6I5F|rcsb pdb:7AI6|rcsb pdb:7AI7|rcsb pdb:7AIB|rcsb pdb:7AIC psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/06 2017/08/10 rogid:hhZYhMtr5JC1lGIKtR1wxHAd3JY83333 rogid:dATh7ZKvCBDCX9StM+kqKD3kZ+w83333 rigid:HePQPhJm5qobtDJhBHOtw/J9ySY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P23367 uniprotkb:P23909 intact:EBI-554913|uniprotkb:Q2M6D5|ensemblbacteria:AAC77127|ensemblbacteria:BAE78171 intact:EBI-554920|uniprotkb:P71279|uniprotkb:Q2MA96|ensemblbacteria:AAC75775|ensemblbacteria:BAE76810 psi-mi:mutl_ecoli(display_long)|uniprotkb:mutL(gene name)|psi-mi:mutL(display_short)|uniprotkb:b4170(locus name)|uniprotkb:JW4128(locus name) psi-mi:muts_ecoli(display_long)|uniprotkb:mutS(gene name)|psi-mi:mutS(display_short)|uniprotkb:fdv(gene name synonym)|uniprotkb:b2733(locus name)|uniprotkb:JW2703(locus name) psi-mi:"MI:0096"(pull down) Mendillo et al. (2009) pubmed:20080788|doi:10.1073/pnas.0912250106|imex:IM-15246 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15828769|imex:IM-15246-3|dip:DIP-18041E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_418591.1|refseq:WP_001122505.1|dip:DIP-10285N|ensemblbacteria:AAC77127(transcript)|ensemblbacteria:b4170(gene)|ensemblbacteria:BAE78171(gene)|ensemblbacteria:BAE78171(transcript)|go:"GO:0000018"(regulation of DNA recombination)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0006298"(mismatch repair)|go:"GO:0030983"(mismatched DNA binding)|go:"GO:0032300"(mismatch repair complex)|go:"GO:0042802"(identical protein binding)|interpro:IPR002099(DNA mismatch repair protein)|interpro:IPR013507(DNA mismatch repair protein, C-terminal)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR014762(DNA mismatch repair, conserved site)|interpro:IPR014790(MutL, C-terminal, dimerisation)|interpro:IPR020568|interpro:IPR020667|interpro:IPR036890|interpro:IPR037198|interpro:IPR038973|interpro:IPR042120|interpro:IPR042121|rcsb pdb:1B62|rcsb pdb:1B63|rcsb pdb:1BKN|rcsb pdb:1NHH|rcsb pdb:1NHI|rcsb pdb:1NHJ|rcsb pdb:1X9Z|rcsb pdb:5AKB|rcsb pdb:5AKC|rcsb pdb:5AKD|rcsb pdb:6E8E|rcsb pdb:7AIB|rcsb pdb:7AIC refseq:NP_417213.1|refseq:WP_001272928.1|dip:DIP-10287N|ensemblbacteria:AAC75775(transcript)|ensemblbacteria:b2733(gene)|ensemblbacteria:BAE76810(gene)|ensemblbacteria:BAE76810(transcript)|go:"GO:0000018"(regulation of DNA recombination)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006298"(mismatch repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0030983"(mismatched DNA binding)|go:"GO:0032136"(adenine/cytosine mispair binding)|go:"GO:0032300"(mismatch repair complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043531"(ADP binding)|interpro:IPR000432(DNA mismatch repair protein MutS, C-terminal)|interpro:IPR005748(DNA mismatch repair protein MutS, type 1)|interpro:IPR007695(DNA mismatch repair protein MutS-like, N-terminal)|interpro:IPR007696(DNA mismatch repair protein MutS, core)|interpro:IPR007860(DNA mismatch repair protein MutS, connector)|interpro:IPR007861(DNA mismatch repair protein MutS, clamp)|interpro:IPR016151(DNA mismatch repair protein MutS, N-terminal)|interpro:IPR017261(DNA mismatch repair protein Msh6)|interpro:IPR027417|interpro:IPR036187|interpro:IPR036678|rcsb pdb:1E3M|rcsb pdb:1NG9|rcsb pdb:1OH5|rcsb pdb:1OH6|rcsb pdb:1OH7|rcsb pdb:1OH8|rcsb pdb:1W7A|rcsb pdb:1WB9|rcsb pdb:1WBB|rcsb pdb:1WBD|rcsb pdb:2OK2|rcsb pdb:2WTU|rcsb pdb:3K0S|rcsb pdb:3ZLJ|rcsb pdb:5AKB|rcsb pdb:5AKC|rcsb pdb:5AKD|rcsb pdb:6I5F|rcsb pdb:7AI6|rcsb pdb:7AI7|rcsb pdb:7AIB|rcsb pdb:7AIC psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/06 2017/08/10 rogid:hhZYhMtr5JC1lGIKtR1wxHAd3JY83333 rogid:dATh7ZKvCBDCX9StM+kqKD3kZ+w83333 rigid:HePQPhJm5qobtDJhBHOtw/J9ySY false - binding-associated region:116-266|maltose binding protein tag:n-n - - psi-mi:"MI:0817"(molecular weight estimation by silver staining) psi-mi:"MI:0817"(molecular weight estimation by silver staining) uniprotkb:P38920 uniprotkb:P14242 intact:EBI-11003|uniprotkb:Q2I028|uniprotkb:Q2I029|uniprotkb:Q2I031|uniprotkb:Q2I032|uniprotkb:Q2I033|uniprotkb:Q2I034|uniprotkb:Q2I035|uniprotkb:Q2I036|uniprotkb:Q2I038|uniprotkb:Q2I039|uniprotkb:Q2I041|ensemblfungi:YMR167W|uniprotkb:D6VZY9 intact:EBI-13561|uniprotkb:Q2I044|uniprotkb:Q2I045|uniprotkb:Q45TY4|uniprotkb:Q8TG48|uniprotkb:Q8TG50|uniprotkb:Q8TG54|uniprotkb:Q8TG57|uniprotkb:D6W197|ensemblfungi:YNL082W psi-mi:mlh1_yeast(display_long)|uniprotkb:MLH1(gene name)|psi-mi:MLH1(display_short)|uniprotkb:YMR167W(locus name)|uniprotkb:YM8520.16(orf name)|uniprotkb:PMS2(gene name synonym)|uniprotkb:MutL protein homolog 1(gene name synonym)|uniprotkb:Post meiotic segregation protein 2(gene name synonym) psi-mi:pms1_yeast(display_long)|uniprotkb:PMS1(gene name)|psi-mi:PMS1(display_short)|uniprotkb:YNL082W(locus name)|uniprotkb:N2317(orf name)|uniprotkb:Postmeiotic segregation protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Mendillo et al. (2009) pubmed:20080788|doi:10.1073/pnas.0912250106|imex:IM-15246 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15828811|imex:IM-15246-5|dip:DIP-2913E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6SNS|rcsb pdb:6SNV|reactome:R-SCE-5358565|ensemblfungi:YMR167W(gene)|ensemblfungi:YMR167W_mRNA(transcript)|go:"GO:0000710"(meiotic mismatch repair)|go:"GO:0000713"(meiotic heteroduplex formation)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006298"(mismatch repair)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0030983"(mismatched DNA binding)|go:"GO:0032300"(mismatch repair complex)|go:"GO:0032389"(MutLalpha complex)|go:"GO:0032390"(MutLbeta complex)|go:"GO:0097587"(MutLgamma complex)|interpro:IPR002099(DNA mismatch repair protein)|interpro:IPR013507(DNA mismatch repair protein, C-terminal)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR014762(DNA mismatch repair, conserved site)|interpro:IPR020568|interpro:IPR032189|interpro:IPR036890|interpro:IPR038973|rcsb pdb:4E4W|rcsb pdb:4FMN|rcsb pdb:4FMO|rcsb pdb:6RMN|rcsb pdb:6SHX|refseq:NP_013890.1|sgd:S000004777|mint:P38920|dip:DIP-2412N sgd:S000005026|refseq:NP_014317.4|ensemblfungi:YNL082W(gene)|ensemblfungi:YNL082W_mRNA(transcript)|go:"GO:0000710"(meiotic mismatch repair)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006298"(mismatch repair)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0030983"(mismatched DNA binding)|go:"GO:0032300"(mismatch repair complex)|go:"GO:0032389"(MutLalpha complex)|interpro:IPR002099(DNA mismatch repair protein)|interpro:IPR013507(DNA mismatch repair protein, C-terminal)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR014762(DNA mismatch repair, conserved site)|interpro:IPR014790(MutL, C-terminal, dimerisation)|interpro:IPR020568|interpro:IPR036890|interpro:IPR037198|interpro:IPR038973|interpro:IPR042121|rcsb pdb:3H4L|rcsb pdb:4E4W|rcsb pdb:4FMN|rcsb pdb:4FMO|reactome:R-SCE-5358565|mint:P14242|dip:DIP-2416N psi-mi:"MI:0465"(dip) crc64:B2DBB31DE3943171 crc64:2E0FFBC59B718854 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/06 2017/08/10 rogid:rZq8/zWV2xAiYIDDuGGsp+YjSnY559292 rogid:JMHy1ud9pY728nqxAv82qHJ6eZk559292 rigid:xB+nuhExIJTnwHXwIAQ2ix0fvKw false - flag tag:c-c - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P23367 uniprotkb:P23909 intact:EBI-554913|uniprotkb:Q2M6D5|ensemblbacteria:AAC77127|ensemblbacteria:BAE78171 intact:EBI-554920|uniprotkb:P71279|uniprotkb:Q2MA96|ensemblbacteria:AAC75775|ensemblbacteria:BAE76810 psi-mi:mutl_ecoli(display_long)|uniprotkb:mutL(gene name)|psi-mi:mutL(display_short)|uniprotkb:b4170(locus name)|uniprotkb:JW4128(locus name) psi-mi:muts_ecoli(display_long)|uniprotkb:mutS(gene name)|psi-mi:mutS(display_short)|uniprotkb:fdv(gene name synonym)|uniprotkb:b2733(locus name)|uniprotkb:JW2703(locus name) psi-mi:"MI:0944"(mass spectrometry study of hydrogen/deuterium exchange) Mendillo et al. (2009) pubmed:20080788|doi:10.1073/pnas.0912250106|imex:IM-15246 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15828790|imex:IM-15246-4|dip:DIP-18041E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_418591.1|refseq:WP_001122505.1|dip:DIP-10285N|ensemblbacteria:AAC77127(transcript)|ensemblbacteria:b4170(gene)|ensemblbacteria:BAE78171(gene)|ensemblbacteria:BAE78171(transcript)|go:"GO:0000018"(regulation of DNA recombination)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0006298"(mismatch repair)|go:"GO:0030983"(mismatched DNA binding)|go:"GO:0032300"(mismatch repair complex)|go:"GO:0042802"(identical protein binding)|interpro:IPR002099(DNA mismatch repair protein)|interpro:IPR013507(DNA mismatch repair protein, C-terminal)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR014762(DNA mismatch repair, conserved site)|interpro:IPR014790(MutL, C-terminal, dimerisation)|interpro:IPR020568|interpro:IPR020667|interpro:IPR036890|interpro:IPR037198|interpro:IPR038973|interpro:IPR042120|interpro:IPR042121|rcsb pdb:1B62|rcsb pdb:1B63|rcsb pdb:1BKN|rcsb pdb:1NHH|rcsb pdb:1NHI|rcsb pdb:1NHJ|rcsb pdb:1X9Z|rcsb pdb:5AKB|rcsb pdb:5AKC|rcsb pdb:5AKD|rcsb pdb:6E8E|rcsb pdb:7AIB|rcsb pdb:7AIC refseq:NP_417213.1|refseq:WP_001272928.1|dip:DIP-10287N|ensemblbacteria:AAC75775(transcript)|ensemblbacteria:b2733(gene)|ensemblbacteria:BAE76810(gene)|ensemblbacteria:BAE76810(transcript)|go:"GO:0000018"(regulation of DNA recombination)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006298"(mismatch repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0030983"(mismatched DNA binding)|go:"GO:0032136"(adenine/cytosine mispair binding)|go:"GO:0032300"(mismatch repair complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043531"(ADP binding)|interpro:IPR000432(DNA mismatch repair protein MutS, C-terminal)|interpro:IPR005748(DNA mismatch repair protein MutS, type 1)|interpro:IPR007695(DNA mismatch repair protein MutS-like, N-terminal)|interpro:IPR007696(DNA mismatch repair protein MutS, core)|interpro:IPR007860(DNA mismatch repair protein MutS, connector)|interpro:IPR007861(DNA mismatch repair protein MutS, clamp)|interpro:IPR016151(DNA mismatch repair protein MutS, N-terminal)|interpro:IPR017261(DNA mismatch repair protein Msh6)|interpro:IPR027417|interpro:IPR036187|interpro:IPR036678|rcsb pdb:1E3M|rcsb pdb:1NG9|rcsb pdb:1OH5|rcsb pdb:1OH6|rcsb pdb:1OH7|rcsb pdb:1OH8|rcsb pdb:1W7A|rcsb pdb:1WB9|rcsb pdb:1WBB|rcsb pdb:1WBD|rcsb pdb:2OK2|rcsb pdb:2WTU|rcsb pdb:3K0S|rcsb pdb:3ZLJ|rcsb pdb:5AKB|rcsb pdb:5AKC|rcsb pdb:5AKD|rcsb pdb:6I5F|rcsb pdb:7AI6|rcsb pdb:7AI7|rcsb pdb:7AIB|rcsb pdb:7AIC psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/06 2017/08/10 rogid:hhZYhMtr5JC1lGIKtR1wxHAd3JY83333 rogid:dATh7ZKvCBDCX9StM+kqKD3kZ+w83333 rigid:HePQPhJm5qobtDJhBHOtw/J9ySY false - binding-associated region:205-213|binding-associated region:674-688 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P14242 uniprotkb:P25847 intact:EBI-13561|uniprotkb:Q2I044|uniprotkb:Q2I045|uniprotkb:Q45TY4|uniprotkb:Q8TG48|uniprotkb:Q8TG50|uniprotkb:Q8TG54|uniprotkb:Q8TG57|uniprotkb:D6W197|ensemblfungi:YNL082W intact:EBI-11352|uniprotkb:Q12423|ensemblfungi:YOL090W|uniprotkb:D6W1X8 psi-mi:pms1_yeast(display_long)|uniprotkb:PMS1(gene name)|psi-mi:PMS1(display_short)|uniprotkb:YNL082W(locus name)|uniprotkb:N2317(orf name)|uniprotkb:Postmeiotic segregation protein 1(gene name synonym) psi-mi:msh2_yeast(display_long)|uniprotkb:MSH2(gene name)|psi-mi:MSH2(display_short)|uniprotkb:YOL090W(locus name)|uniprotkb:O0935(orf name)|uniprotkb:MutS protein homolog 2(gene name synonym) psi-mi:"MI:0096"(pull down) Mendillo et al. (2009) pubmed:20080788|doi:10.1073/pnas.0912250106|imex:IM-15246 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15828830|imex:IM-15246-6|dip:DIP-2923E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005026|refseq:NP_014317.4|ensemblfungi:YNL082W(gene)|ensemblfungi:YNL082W_mRNA(transcript)|go:"GO:0000710"(meiotic mismatch repair)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006298"(mismatch repair)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0030983"(mismatched DNA binding)|go:"GO:0032300"(mismatch repair complex)|go:"GO:0032389"(MutLalpha complex)|interpro:IPR002099(DNA mismatch repair protein)|interpro:IPR013507(DNA mismatch repair protein, C-terminal)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR014762(DNA mismatch repair, conserved site)|interpro:IPR014790(MutL, C-terminal, dimerisation)|interpro:IPR020568|interpro:IPR036890|interpro:IPR037198|interpro:IPR038973|interpro:IPR042121|rcsb pdb:3H4L|rcsb pdb:4E4W|rcsb pdb:4FMN|rcsb pdb:4FMO|reactome:R-SCE-5358565|mint:P14242|dip:DIP-2416N ensemblfungi:YOL090W(gene)|ensemblfungi:YOL090W_mRNA(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000400"(four-way junction DNA binding)|go:"GO:0000406"(double-strand/single-strand DNA junction binding)|go:"GO:0000710"(meiotic mismatch repair)|go:"GO:0000735"(removal of nonhomologous ends)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006298"(mismatch repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006311"(meiotic gene conversion)|go:"GO:0006312"(mitotic recombination)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0030983"(mismatched DNA binding)|go:"GO:0032301"(MutSalpha complex)|go:"GO:0032302"(MutSbeta complex)|go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0043111"(replication fork arrest)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0045910"(negative regulation of DNA recombination)|interpro:IPR000432(DNA mismatch repair protein MutS, C-terminal)|interpro:IPR007695(DNA mismatch repair protein MutS-like, N-terminal)|interpro:IPR007696(DNA mismatch repair protein MutS, core)|interpro:IPR007860(DNA mismatch repair protein MutS, connector)|interpro:IPR007861(DNA mismatch repair protein MutS, clamp)|interpro:IPR011184(DNA mismatch repair protein, MSH2)|interpro:IPR016151(DNA mismatch repair protein MutS, N-terminal)|interpro:IPR027417|interpro:IPR032642|interpro:IPR036187|interpro:IPR036678|reactome:R-SCE-5358565|reactome:R-SCE-5358606|go:"GO:0032300"(mismatch repair complex)|refseq:NP_014551.1|sgd:S000005450|mint:P25847|dip:DIP-2415N psi-mi:"MI:0465"(dip) crc64:2E0FFBC59B718854 crc64:43FFD8A640138AE4 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/06 2017/08/10 rogid:JMHy1ud9pY728nqxAv82qHJ6eZk559292 rogid:PNwekSiaI58qR+dPZZQW5UNRJ+4559292 rigid:Z2o7yIvCBjHoheHzJL6TejaFE/0 false flag tag:c-c binding-associated region:121-294|maltose binding protein tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot)