#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P00740 uniprotkb:P01008 intact:EBI-9640450|uniprotkb:A8K9N4|uniprotkb:Q5JYJ8|uniprotkb:F2RM36|uniprotkb:Q5FBE1|ensembl:ENSP00000218099 intact:EBI-1039832|uniprotkb:P78439|uniprotkb:P78447|uniprotkb:Q13815|uniprotkb:Q7KZ43|uniprotkb:B2R6P0|uniprotkb:Q5TC78|uniprotkb:Q7KZ97|uniprotkb:Q9UC78|ensembl:ENSP00000356671 psi-mi:fa9_human(display_long)|uniprotkb:F9(gene name)|psi-mi:F9(display_short)|uniprotkb:Christmas factor(gene name synonym)|uniprotkb:Plasma thromboplastin component(gene name synonym) psi-mi:ant3_human(display_long)|uniprotkb:SERPINC1(gene name)|psi-mi:SERPINC1(display_short)|uniprotkb:AT3(gene name synonym)|uniprotkb:PRO0309(orf name)|uniprotkb:Serpin C1(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Johnson et al. (2010) pubmed:20080729|doi:10.1073/pnas.0910144107|imex:IM-14922 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15828162|imex:IM-14922-1|dip:DIP-185499E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001300842.1|refseq:NP_000124.1|dip:DIP-58520N|ensembl:ENSG00000101981(gene)|ensembl:ENST00000218099(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005796"(Golgi lumen)|go:"GO:0005886"(plasma membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0007596"(blood coagulation)|go:"GO:0031638"(zymogen activation)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000294(Vitamin K-dependent carboxylation/gamma-carboxyglutamic region)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR012224(Peptidase S1A, coagulation factor VII/IX/X/C/Z)|interpro:IPR017857(Coagulation factor, subset, Gla region)|interpro:IPR018097|interpro:IPR018114|interpro:IPR033116|interpro:IPR035694|interpro:IPR035972|interpro:IPR043504|rcsb pdb:1CFH|rcsb pdb:1CFI|rcsb pdb:1EDM|rcsb pdb:1IXA|rcsb pdb:1MGX|rcsb pdb:1NL0|rcsb pdb:1RFN|rcsb pdb:2WPH|rcsb pdb:2WPI|rcsb pdb:2WPJ|rcsb pdb:2WPK|rcsb pdb:2WPL|rcsb pdb:2WPM|rcsb pdb:3KCG|rcsb pdb:3LC3|rcsb pdb:3LC5|rcsb pdb:4WM0|rcsb pdb:4WMA|rcsb pdb:4WMB|rcsb pdb:4WMI|rcsb pdb:4WMK|rcsb pdb:4WN2|rcsb pdb:4WNH|rcsb pdb:4YZU|rcsb pdb:4Z0K|rcsb pdb:4ZAE|rcsb pdb:5EGM|rcsb pdb:5F84|rcsb pdb:5F85|rcsb pdb:5F86|rcsb pdb:5JB8|rcsb pdb:5JB9|rcsb pdb:5JBA|rcsb pdb:5JBB|rcsb pdb:5JBC|rcsb pdb:5TNO|rcsb pdb:5TNT|rcsb pdb:5VYG|rcsb pdb:6MV4|rcsb pdb:6RFK|rcsb pdb:6X5J|rcsb pdb:6X5L|rcsb pdb:6X5P|reactome:R-HSA-140834|reactome:R-HSA-140837|reactome:R-HSA-159740|reactome:R-HSA-159763|reactome:R-HSA-159782|reactome:R-HSA-9672383|reactome:R-HSA-9672396|reactome:R-HSA-9673202|reactome:R-HSA-9673218|reactome:R-HSA-9673221|reactome:R-HSA-9673240|mint:P00740 refseq:NP_000479.1|ensembl:ENSG00000117601(gene)|ensembl:ENST00000367698(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0002438"(acute inflammatory response to antigenic stimulus)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005886"(plasma membrane)|go:"GO:0007584"(response to nutrient)|go:"GO:0007595"(lactation)|go:"GO:0007596"(blood coagulation)|go:"GO:0008201"(heparin binding)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:2000266"(regulation of blood coagulation, intrinsic pathway)|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR015555(Protease inhibitor I4, serpin, antithrombin-III)|interpro:IPR023795|interpro:IPR023796|interpro:IPR033829|interpro:IPR036186|interpro:IPR042178|interpro:IPR042185|mint:P01008|rcsb pdb:1ANT|rcsb pdb:1ATH|rcsb pdb:1AZX|rcsb pdb:1BR8|rcsb pdb:1DZG|rcsb pdb:1DZH|rcsb pdb:1E03|rcsb pdb:1E04|rcsb pdb:1E05|rcsb pdb:1JVQ|rcsb pdb:1LK6|rcsb pdb:1NQ9|rcsb pdb:1OYH|rcsb pdb:1R1L|rcsb pdb:1SR5|rcsb pdb:1T1F|rcsb pdb:1TB6|rcsb pdb:2ANT|rcsb pdb:2B4X|rcsb pdb:2B5T|rcsb pdb:2BEH|rcsb pdb:2GD4|rcsb pdb:2HIJ|rcsb pdb:2ZNH|rcsb pdb:3EVJ|rcsb pdb:3KCG|rcsb pdb:4EB1|reactome:R-HSA-140837|reactome:R-HSA-140875|reactome:R-HSA-381426|reactome:R-HSA-8957275|dip:DIP-38009N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/06 2017/08/10 rogid:WgF6aC2nvjTyYTwIhMpWd2paXgI9606 rogid:XiPmXyU7CpPTgDR3dPnKeJEItJg9606 rigid:XcL1c7RXo9cYlGtLQhSe6edNal8 false binding-associated region:103-431 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)