#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P06780 uniprotkb:P33332 intact:EBI-15121|uniprotkb:D6W4G6|ensemblfungi:YPR165W intact:EBI-16850|uniprotkb:D3DLQ5|ensemblfungi:YER008C psi-mi:rho1_yeast(display_long)|uniprotkb:RHO1(gene name)|psi-mi:RHO1(display_short)|uniprotkb:YPR165W(locus name)|uniprotkb:P9325.3(orf name)|uniprotkb:Rho-type GTPase 1(gene name synonym) psi-mi:sec3_yeast(display_long)|uniprotkb:PSL1(gene name synonym)|uniprotkb:YER008C(locus name)|uniprotkb:SEC3(gene name)|psi-mi:SEC3(display_short)|uniprotkb:Protein PSL1(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Yamashita et al. (2010) pubmed:20062059|doi:10.1038/nsmb.1722|imex:IM-14678 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15825170|imex:IM-14678-1|dip:DIP-10874E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015491.1|sgd:S000006369|reactome:R-SCE-6798695|reactome:R-SCE-8980692|reactome:R-SCE-9013026|reactome:R-SCE-9013405|reactome:R-SCE-9035034|reactome:R-SCE-9696264|reactome:R-SCE-9696270|reactome:R-SCE-9696273|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0032186"(cellular bud neck septin ring organization)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032889"(regulation of vacuole fusion, non-autophagic)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0042995"(cell projection)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043332"(mating projection tip)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0060178"(regulation of exocyst localization)|go:"GO:0060237"(regulation of fungal-type cell wall organization)|go:"GO:0071944"(cell periphery)|go:"GO:0090037"(positive regulation of protein kinase C signaling)|go:"GO:0090334"("regulation of cell wall (1->3)-beta-D-glucan biosynthetic process")|go:"GO:1903395"(regulation of secondary cell septum biogenesis)|go:"GO:1903501"(positive regulation of mitotic actomyosin contractile ring assembly)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|rcsb pdb:3A58|reactome:R-SCE-198203|reactome:R-SCE-392451|reactome:R-SCE-416482|reactome:R-SCE-5625740|ensemblfungi:YPR165W(gene)|ensemblfungi:YPR165W_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0000148"(1,3-beta-D-glucan synthase complex)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005933"(cellular bud)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0005938"(cell cortex)|go:"GO:0007015"(actin filament organization)|go:"GO:0007117"(budding cell bud growth)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0008361"(regulation of cell size)|go:"GO:0010008"(endosome membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030865"(cortical cytoskeleton organization)|go:"GO:0031410"(cytoplasmic vesicle)|dip:DIP-1040N|mint:P06780 refseq:NP_010924.1|sgd:S000000810|ensemblfungi:YER008C(gene)|ensemblfungi:YER008C_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0000145"(exocyst)|go:"GO:0001927"(exocyst assembly)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005628"(prospore membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005934"(cellular bud tip)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0015031"(protein transport)|go:"GO:0031267"(small GTPase binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0048309"(endoplasmic reticulum inheritance)|go:"GO:0051601"(exocyst localization)|go:"GO:0090522"(vesicle tethering involved in exocytosis)|interpro:IPR019160|interpro:IPR028258|rcsb pdb:3A58|rcsb pdb:3HIE|rcsb pdb:5LG4|rcsb pdb:5M4Y|rcsb pdb:5YFP|rcsb pdb:6VKL|reactome:R-SCE-264876|go:"GO:0005935"(cellular bud neck)|dip:DIP-5992N|mint:P33332 psi-mi:"MI:0465"(dip) crc64:630B17E9E34CFE75 crc64:6F0C1BF13A77985E full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/06 2017/08/10 rogid:DHzmbB2VfZP/fwD9FzdTnXOc8aA559292 rogid:WiANgpTOjGE+lWQyuwInxp3ftCk559292 rigid:1CUB63FfNx5HrhBvmYcNZ8BDdVY false binding-associated region:1-188 binding-associated region:1-320 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P06780 uniprotkb:P33332 intact:EBI-15121|uniprotkb:D6W4G6|ensemblfungi:YPR165W intact:EBI-16850|uniprotkb:D3DLQ5|ensemblfungi:YER008C psi-mi:rho1_yeast(display_long)|uniprotkb:RHO1(gene name)|psi-mi:RHO1(display_short)|uniprotkb:YPR165W(locus name)|uniprotkb:P9325.3(orf name)|uniprotkb:Rho-type GTPase 1(gene name synonym) psi-mi:sec3_yeast(display_long)|uniprotkb:PSL1(gene name synonym)|uniprotkb:YER008C(locus name)|uniprotkb:SEC3(gene name)|psi-mi:SEC3(display_short)|uniprotkb:Protein PSL1(gene name synonym) psi-mi:"MI:0096"(pull down) Yamashita et al. (2010) pubmed:20062059|doi:10.1038/nsmb.1722|imex:IM-14678 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15825191|imex:IM-14678-2|dip:DIP-10874E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015491.1|sgd:S000006369|reactome:R-SCE-6798695|reactome:R-SCE-8980692|reactome:R-SCE-9013026|reactome:R-SCE-9013405|reactome:R-SCE-9035034|reactome:R-SCE-9696264|reactome:R-SCE-9696270|reactome:R-SCE-9696273|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0032186"(cellular bud neck septin ring organization)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032889"(regulation of vacuole fusion, non-autophagic)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0042995"(cell projection)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043332"(mating projection tip)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0060178"(regulation of exocyst localization)|go:"GO:0060237"(regulation of fungal-type cell wall organization)|go:"GO:0071944"(cell periphery)|go:"GO:0090037"(positive regulation of protein kinase C signaling)|go:"GO:0090334"("regulation of cell wall (1->3)-beta-D-glucan biosynthetic process")|go:"GO:1903395"(regulation of secondary cell septum biogenesis)|go:"GO:1903501"(positive regulation of mitotic actomyosin contractile ring assembly)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|rcsb pdb:3A58|reactome:R-SCE-198203|reactome:R-SCE-392451|reactome:R-SCE-416482|reactome:R-SCE-5625740|ensemblfungi:YPR165W(gene)|ensemblfungi:YPR165W_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0000148"(1,3-beta-D-glucan synthase complex)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005933"(cellular bud)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0005938"(cell cortex)|go:"GO:0007015"(actin filament organization)|go:"GO:0007117"(budding cell bud growth)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0008361"(regulation of cell size)|go:"GO:0010008"(endosome membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030865"(cortical cytoskeleton organization)|go:"GO:0031410"(cytoplasmic vesicle)|dip:DIP-1040N|mint:P06780 refseq:NP_010924.1|sgd:S000000810|ensemblfungi:YER008C(gene)|ensemblfungi:YER008C_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0000145"(exocyst)|go:"GO:0001927"(exocyst assembly)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005628"(prospore membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005934"(cellular bud tip)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0015031"(protein transport)|go:"GO:0031267"(small GTPase binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0048309"(endoplasmic reticulum inheritance)|go:"GO:0051601"(exocyst localization)|go:"GO:0090522"(vesicle tethering involved in exocytosis)|interpro:IPR019160|interpro:IPR028258|rcsb pdb:3A58|rcsb pdb:3HIE|rcsb pdb:5LG4|rcsb pdb:5M4Y|rcsb pdb:5YFP|rcsb pdb:6VKL|reactome:R-SCE-264876|go:"GO:0005935"(cellular bud neck)|dip:DIP-5992N|mint:P33332 psi-mi:"MI:0465"(dip) crc64:630B17E9E34CFE75 crc64:6F0C1BF13A77985E full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/06 2017/08/10 rogid:DHzmbB2VfZP/fwD9FzdTnXOc8aA559292 rogid:WiANgpTOjGE+lWQyuwInxp3ftCk559292 rigid:1CUB63FfNx5HrhBvmYcNZ8BDdVY false binding-associated region:1-188|mutation disrupting interaction:43-43|mutation disrupting interaction:44-44|mutation disrupting interaction:68-68|mutation disrupting interaction:71-71|mutation disrupting interaction:73-73|glutathione s tranferase tag:n-n binding-associated region:1-320|mutation disrupting interaction:131-131|mutation disrupting interaction:136-136|mutation disrupting interaction:199-199 - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)