#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
intact:EBI-15822199	uniprotkb:Q04756	dip:DIP-48340N	intact:EBI-1041722|uniprotkb:Q14726|uniprotkb:Q2M1W7|uniprotkb:Q53X47|ensembl:ENSP00000372224	psi-mi:kqlr(display_short)|psi-mi:EBI-15822199(display_long)	psi-mi:hgfa_human(display_long)|uniprotkb:HGFAC(gene name)|psi-mi:HGFAC(display_short)	psi-mi:"MI:0071"(molecular sieving)	Ganesan et al. (2009)	pubmed:20004165|doi:10.1016/j.str.2009.09.014|imex:IM-11801	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15822202|imex:IM-11801-1|dip:DIP-102579E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0327"(peptide)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001519.1|ensembl:ENSG00000109758(gene)|ensembl:ENST00000382774(transcript)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006508"(proteolysis)|go:"GO:0007596"(blood coagulation)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0031638"(zymogen activation)|interpro:IPR000001(Kringle)|interpro:IPR000083(Fibronectin, type I)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR013806(Kringle-like fold)|interpro:IPR014394(Coagulation factor XII/hepatocyte growth factor activator)|interpro:IPR018056|interpro:IPR018114|interpro:IPR033116|interpro:IPR036943|interpro:IPR038178|interpro:IPR043504|rcsb pdb:1YBW|rcsb pdb:1YC0|rcsb pdb:2R0K|rcsb pdb:2R0L|rcsb pdb:2WUB|rcsb pdb:3K2U|reactome:R-HSA-6806942|rcsb pdb:2WUC|refseq:NP_001284368.1|dip:DIP-6022N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/06	2017/08/10	rogid:QKcdOcYU0iAn4RipxJ4TbJETk2E-2	rogid:wUngo1v72gxjGSfz7ikz7sJkLHA9606	rigid:e7jVGF1UPIVmBPJm9CU2j9yiyYs	false	-	binding-associated region:373-655	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O43278-1	uniprotkb:Q04756	intact:EBI-15822221|ensembl:ENSP00000342098	intact:EBI-1041722|uniprotkb:Q14726|uniprotkb:Q2M1W7|uniprotkb:Q53X47|ensembl:ENSP00000372224	psi-mi:o43278-1(display_long)|uniprotkb:UNQ223/PRO256(orf name)|uniprotkb:HAI-1B(isoform synonym)|uniprotkb:Hepatocyte growth factor activator inhibitor type 1(gene name synonym)|uniprotkb:SPINT1(gene name)|psi-mi:SPINT1(display_short)|uniprotkb:HAI1(gene name synonym)	psi-mi:hgfa_human(display_long)|uniprotkb:HGFAC(gene name)|psi-mi:HGFAC(display_short)	psi-mi:"MI:0411"(enzyme linked immunosorbent assay)	Ganesan et al. (2009)	pubmed:20004165|doi:10.1016/j.str.2009.09.014|imex:IM-11801	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15822231|imex:IM-11801-2|dip:DIP-65929E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000166145(gene)|ensembl:ENST00000344051(transcript)|intact:EBI-953990(isoform-parent)	refseq:NP_001519.1|ensembl:ENSG00000109758(gene)|ensembl:ENST00000382774(transcript)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006508"(proteolysis)|go:"GO:0007596"(blood coagulation)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0031638"(zymogen activation)|interpro:IPR000001(Kringle)|interpro:IPR000083(Fibronectin, type I)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR013806(Kringle-like fold)|interpro:IPR014394(Coagulation factor XII/hepatocyte growth factor activator)|interpro:IPR018056|interpro:IPR018114|interpro:IPR033116|interpro:IPR036943|interpro:IPR038178|interpro:IPR043504|rcsb pdb:1YBW|rcsb pdb:1YC0|rcsb pdb:2R0K|rcsb pdb:2R0L|rcsb pdb:2WUB|rcsb pdb:3K2U|reactome:R-HSA-6806942|rcsb pdb:2WUC|refseq:NP_001284368.1|dip:DIP-6022N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/06	2017/08/10	rogid:feHnyLQq6rOSG2IW9dCGVBkcurg9606	rogid:wUngo1v72gxjGSfz7ikz7sJkLHA9606	rigid:+Fm9JsP+3WBmvsH73bzv3qYWlpE	false	biotin tag:?-?	binding-associated region:373-655	-	-	psi-mi:"MI:0866"(tag visualisation)	psi-mi:"MI:0866"(tag visualisation)
intact:EBI-15822199	uniprotkb:Q04756	dip:DIP-48340N	intact:EBI-1041722|uniprotkb:Q14726|uniprotkb:Q2M1W7|uniprotkb:Q53X47|ensembl:ENSP00000372224	psi-mi:kqlr(display_short)|psi-mi:EBI-15822199(display_long)	psi-mi:hgfa_human(display_long)|uniprotkb:HGFAC(gene name)|psi-mi:HGFAC(display_short)	psi-mi:"MI:0114"(x-ray crystallography)	Ganesan et al. (2009)	pubmed:20004165|doi:10.1016/j.str.2009.09.014|imex:IM-11801	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15822253|imex:IM-11801-3|dip:DIP-102579E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0327"(peptide)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001519.1|ensembl:ENSG00000109758(gene)|ensembl:ENST00000382774(transcript)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006508"(proteolysis)|go:"GO:0007596"(blood coagulation)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0031638"(zymogen activation)|interpro:IPR000001(Kringle)|interpro:IPR000083(Fibronectin, type I)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR013806(Kringle-like fold)|interpro:IPR014394(Coagulation factor XII/hepatocyte growth factor activator)|interpro:IPR018056|interpro:IPR018114|interpro:IPR033116|interpro:IPR036943|interpro:IPR038178|interpro:IPR043504|rcsb pdb:1YBW|rcsb pdb:1YC0|rcsb pdb:2R0K|rcsb pdb:2R0L|rcsb pdb:2WUB|rcsb pdb:3K2U|reactome:R-HSA-6806942|rcsb pdb:2WUC|refseq:NP_001284368.1|dip:DIP-6022N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/06	2017/08/10	rogid:QKcdOcYU0iAn4RipxJ4TbJETk2E-2	rogid:wUngo1v72gxjGSfz7ikz7sJkLHA9606	rigid:e7jVGF1UPIVmBPJm9CU2j9yiyYs	false	-	binding-associated region:373-655	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q04756	uniprotkb:P14210	intact:EBI-1041722|uniprotkb:Q14726|uniprotkb:Q2M1W7|uniprotkb:Q53X47|ensembl:ENSP00000372224	intact:EBI-1039104|uniprotkb:A1L3U6|uniprotkb:Q02935|uniprotkb:Q13494|uniprotkb:Q14519|uniprotkb:Q8TCE2|uniprotkb:Q9BYL9|uniprotkb:Q9BYM0|uniprotkb:Q9UDU6|uniprotkb:Q3KRB2|ensembl:ENSP00000222390	psi-mi:hgfa_human(display_long)|uniprotkb:HGFAC(gene name)|psi-mi:HGFAC(display_short)	psi-mi:hgf_human(display_long)|uniprotkb:HGF(gene name)|psi-mi:HGF(display_short)|uniprotkb:HPTA(gene name synonym)|uniprotkb:Scatter factor(gene name synonym)|uniprotkb:Hepatopoietin-A(gene name synonym)	psi-mi:"MI:0435"(protease assay)	Ganesan et al. (2009)	pubmed:20004165|doi:10.1016/j.str.2009.09.014|imex:IM-11801	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0194"(cleavage reaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15822272|imex:IM-11801-4|dip:DIP-102580E	-	-	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001519.1|ensembl:ENSG00000109758(gene)|ensembl:ENST00000382774(transcript)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006508"(proteolysis)|go:"GO:0007596"(blood coagulation)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0031638"(zymogen activation)|interpro:IPR000001(Kringle)|interpro:IPR000083(Fibronectin, type I)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR013806(Kringle-like fold)|interpro:IPR014394(Coagulation factor XII/hepatocyte growth factor activator)|interpro:IPR018056|interpro:IPR018114|interpro:IPR033116|interpro:IPR036943|interpro:IPR038178|interpro:IPR043504|rcsb pdb:1YBW|rcsb pdb:1YC0|rcsb pdb:2R0K|rcsb pdb:2R0L|rcsb pdb:2WUB|rcsb pdb:3K2U|reactome:R-HSA-6806942|rcsb pdb:2WUC|refseq:NP_001284368.1|dip:DIP-6022N	refseq:NP_000592.3|refseq:NP_001010931.1|refseq:NP_001010932.1|refseq:NP_001010933.1|refseq:NP_001010934.1|refseq:XP_006716019.1|go:"GO:0042056"(chemoattractant activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050673"(epithelial cell proliferation)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0070572"(positive regulation of neuron projection regeneration)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1901299"(negative regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1902947"(regulation of tau-protein kinase activity)|go:"GO:2000573"(positive regulation of DNA biosynthetic process)|interpro:IPR000001(Kringle)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR003609(Apple-like)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR013806(Kringle-like fold)|interpro:IPR018056|interpro:IPR024174|interpro:IPR027284|interpro:IPR038178|interpro:IPR043504|rcsb pdb:1BHT|rcsb pdb:1GMN|rcsb pdb:1GMO|rcsb pdb:1GP9|rcsb pdb:1NK1|rcsb pdb:1SHY|rcsb pdb:1SI5|rcsb pdb:2HGF|rcsb pdb:2QJ2|rcsb pdb:3HMS|rcsb pdb:3HMT|rcsb pdb:3HN4|rcsb pdb:3MKP|rcsb pdb:3SP8|rcsb pdb:4D3C|rcsb pdb:4K3J|rcsb pdb:4O3T|rcsb pdb:4O3U|rcsb pdb:5COE|rcsb pdb:5CP9|rcsb pdb:5CS1|rcsb pdb:5CS3|rcsb pdb:5CS5|rcsb pdb:5CS9|rcsb pdb:5CSQ|rcsb pdb:5CT1|rcsb pdb:5CT2|rcsb pdb:5CT3|rcsb pdb:7MO7|rcsb pdb:7MO8|rcsb pdb:7MO9|rcsb pdb:7MOA|rcsb pdb:7MOB|reactome:R-HSA-114608|reactome:R-HSA-1257604|reactome:R-HSA-1266695|reactome:R-HSA-2219530|reactome:R-HSA-5673001|reactome:R-HSA-6785807|reactome:R-HSA-6806942|reactome:R-HSA-6807004|reactome:R-HSA-6811558|reactome:R-HSA-8851805|reactome:R-HSA-8851907|reactome:R-HSA-8865999|reactome:R-HSA-8874081|reactome:R-HSA-8875513|reactome:R-HSA-8875555|reactome:R-HSA-8875656|reactome:R-HSA-8875791|ensembl:ENSG00000019991(gene)|ensembl:ENST00000222390(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0001889"(liver development)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0008083"(growth factor activity)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0030212"(hyaluronan metabolic process)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031643"(positive regulation of myelination)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|refseq:XP_016867586.1|refseq:XP_016867587.1|refseq:XP_011514417.1|dip:DIP-37535N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/06	2017/08/10	rogid:wUngo1v72gxjGSfz7ikz7sJkLHA9606	rogid:qlqHs1bJXvEHZyzrKNZM0VD62pg9606	rigid:9t31GrO2QBln2iC1+rWSyaA4t9I	false	binding-associated region:373-655	125i radiolabel:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)