#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:O75874	uniprotkb:O75874	intact:EBI-715695|uniprotkb:Q567U4|uniprotkb:Q6FHQ6|uniprotkb:Q7Z3V0|uniprotkb:Q93090|uniprotkb:Q9NTJ9|uniprotkb:Q9UKW8|ensembl:ENSP00000260985|ensembl:ENSP00000390265|ensembl:ENSP00000410513	intact:EBI-715695|uniprotkb:Q567U4|uniprotkb:Q6FHQ6|uniprotkb:Q7Z3V0|uniprotkb:Q93090|uniprotkb:Q9NTJ9|uniprotkb:Q9UKW8|ensembl:ENSP00000260985|ensembl:ENSP00000390265|ensembl:ENSP00000410513	psi-mi:idhc_human(display_long)|uniprotkb:Cytosolic NADP-isocitrate dehydrogenase(gene name synonym)|uniprotkb:Oxalosuccinate decarboxylase(gene name synonym)|uniprotkb:"NADP(+)-specific ICDH"(gene name synonym)|uniprotkb:IDP(gene name synonym)|uniprotkb:IDH1(gene name)|psi-mi:IDH1(display_short)|uniprotkb:PICD(gene name synonym)	psi-mi:idhc_human(display_long)|uniprotkb:Cytosolic NADP-isocitrate dehydrogenase(gene name synonym)|uniprotkb:Oxalosuccinate decarboxylase(gene name synonym)|uniprotkb:"NADP(+)-specific ICDH"(gene name synonym)|uniprotkb:IDP(gene name synonym)|uniprotkb:IDH1(gene name)|psi-mi:IDH1(display_short)|uniprotkb:PICD(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Dang et al. (2009)	pubmed:19935646|doi:10.1038/nature08617|imex:IM-16377	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15816535|imex:IM-16377-1|dip:DIP-187537E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005887.2|refseq:NP_001269315.1|refseq:NP_001269316.1|ensembl:ENSG00000138413(gene)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071071"(regulation of phospholipid biosynthetic process)|go:"GO:1904724"(tertiary granule lumen)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004790(Isocitrate dehydrogenase NADP-dependent, eukaryotic)|interpro:IPR019818|interpro:IPR024084|rcsb pdb:1T09|rcsb pdb:1T0L|rcsb pdb:3INM|rcsb pdb:3MAP|rcsb pdb:3MAR|rcsb pdb:3MAS|rcsb pdb:4I3K|go:"GO:0060696"(regulation of phospholipid catabolic process)|rcsb pdb:4I3L|rcsb pdb:4KZO|rcsb pdb:4L03|rcsb pdb:4L04|rcsb pdb:4L06|rcsb pdb:4UMX|rcsb pdb:4UMY|rcsb pdb:4XRX|rcsb pdb:4XS3|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006097"(glyoxylate cycle)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006102"(isocitrate metabolic process)|go:"GO:0006103"(2-oxoglutarate metabolic process)|go:"GO:0006739"(NADP metabolic process)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008585"(female gonad development)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|ensembl:ENST00000345146(transcript)|go:"GO:0045296"(cadherin binding)|ensembl:ENST00000415913(transcript)|ensembl:ENST00000446179(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004450"("isocitrate dehydrogenase (NADP+) activity")|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0050661"(NADP binding)|go:"GO:0051287"(NAD binding)|rcsb pdb:5DE1|rcsb pdb:5GIR|rcsb pdb:5K10|rcsb pdb:5K11|rcsb pdb:5L57|rcsb pdb:5L58|rcsb pdb:5LGE|rcsb pdb:5SUN|rcsb pdb:5SVF|rcsb pdb:5TQH|rcsb pdb:5YFM|rcsb pdb:5YFN|rcsb pdb:6ADG|rcsb pdb:6B0Z|rcsb pdb:6BKX|rcsb pdb:6BKY|rcsb pdb:6BKZ|rcsb pdb:6BL0|rcsb pdb:6BL1|rcsb pdb:6BL2|rcsb pdb:6IO0|rcsb pdb:6VEI|rcsb pdb:6VG0|reactome:R-HSA-389542|reactome:R-HSA-6798695|reactome:R-HSA-2978092|rcsb pdb:6O2Y|rcsb pdb:6O2Z|rcsb pdb:6PAY|rcsb pdb:6Q6F|rcsb pdb:6U4J|reactome:R-HSA-9033241|dip:DIP-59311N	refseq:NP_005887.2|refseq:NP_001269315.1|refseq:NP_001269316.1|ensembl:ENSG00000138413(gene)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071071"(regulation of phospholipid biosynthetic process)|go:"GO:1904724"(tertiary granule lumen)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004790(Isocitrate dehydrogenase NADP-dependent, eukaryotic)|interpro:IPR019818|interpro:IPR024084|rcsb pdb:1T09|rcsb pdb:1T0L|rcsb pdb:3INM|rcsb pdb:3MAP|rcsb pdb:3MAR|rcsb pdb:3MAS|rcsb pdb:4I3K|go:"GO:0060696"(regulation of phospholipid catabolic process)|rcsb pdb:4I3L|rcsb pdb:4KZO|rcsb pdb:4L03|rcsb pdb:4L04|rcsb pdb:4L06|rcsb pdb:4UMX|rcsb pdb:4UMY|rcsb pdb:4XRX|rcsb pdb:4XS3|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006097"(glyoxylate cycle)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006102"(isocitrate metabolic process)|go:"GO:0006103"(2-oxoglutarate metabolic process)|go:"GO:0006739"(NADP metabolic process)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008585"(female gonad development)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|ensembl:ENST00000345146(transcript)|go:"GO:0045296"(cadherin binding)|ensembl:ENST00000415913(transcript)|ensembl:ENST00000446179(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004450"("isocitrate dehydrogenase (NADP+) activity")|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0050661"(NADP binding)|go:"GO:0051287"(NAD binding)|rcsb pdb:5DE1|rcsb pdb:5GIR|rcsb pdb:5K10|rcsb pdb:5K11|rcsb pdb:5L57|rcsb pdb:5L58|rcsb pdb:5LGE|rcsb pdb:5SUN|rcsb pdb:5SVF|rcsb pdb:5TQH|rcsb pdb:5YFM|rcsb pdb:5YFN|rcsb pdb:6ADG|rcsb pdb:6B0Z|rcsb pdb:6BKX|rcsb pdb:6BKY|rcsb pdb:6BKZ|rcsb pdb:6BL0|rcsb pdb:6BL1|rcsb pdb:6BL2|rcsb pdb:6IO0|rcsb pdb:6VEI|rcsb pdb:6VG0|reactome:R-HSA-389542|reactome:R-HSA-6798695|reactome:R-HSA-2978092|rcsb pdb:6O2Y|rcsb pdb:6O2Z|rcsb pdb:6PAY|rcsb pdb:6Q6F|rcsb pdb:6U4J|reactome:R-HSA-9033241|dip:DIP-59311N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:562(ecolx)|taxid:562(Escherichia coli)	-	2017/08/06	2017/08/10	rogid:RFBziMEb70PKCzUCJm2jd40y44M9606	rogid:RFBziMEb70PKCzUCJm2jd40y44M9606	rigid:+IlXPYZxOXfGwAFEkfCngrMWnJ8	false	-	-	-	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O75874	uniprotkb:O75874	intact:EBI-715695|uniprotkb:Q567U4|uniprotkb:Q6FHQ6|uniprotkb:Q7Z3V0|uniprotkb:Q93090|uniprotkb:Q9NTJ9|uniprotkb:Q9UKW8|ensembl:ENSP00000260985|ensembl:ENSP00000390265|ensembl:ENSP00000410513	intact:EBI-715695|uniprotkb:Q567U4|uniprotkb:Q6FHQ6|uniprotkb:Q7Z3V0|uniprotkb:Q93090|uniprotkb:Q9NTJ9|uniprotkb:Q9UKW8|ensembl:ENSP00000260985|ensembl:ENSP00000390265|ensembl:ENSP00000410513	psi-mi:idhc_human(display_long)|uniprotkb:Cytosolic NADP-isocitrate dehydrogenase(gene name synonym)|uniprotkb:Oxalosuccinate decarboxylase(gene name synonym)|uniprotkb:"NADP(+)-specific ICDH"(gene name synonym)|uniprotkb:IDP(gene name synonym)|uniprotkb:IDH1(gene name)|psi-mi:IDH1(display_short)|uniprotkb:PICD(gene name synonym)	psi-mi:idhc_human(display_long)|uniprotkb:Cytosolic NADP-isocitrate dehydrogenase(gene name synonym)|uniprotkb:Oxalosuccinate decarboxylase(gene name synonym)|uniprotkb:"NADP(+)-specific ICDH"(gene name synonym)|uniprotkb:IDP(gene name synonym)|uniprotkb:IDH1(gene name)|psi-mi:IDH1(display_short)|uniprotkb:PICD(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Dang et al. (2009)	pubmed:19935646|doi:10.1038/nature08617|imex:IM-16377	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15816551|imex:IM-16377-2|dip:DIP-187537E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005887.2|refseq:NP_001269315.1|refseq:NP_001269316.1|ensembl:ENSG00000138413(gene)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071071"(regulation of phospholipid biosynthetic process)|go:"GO:1904724"(tertiary granule lumen)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004790(Isocitrate dehydrogenase NADP-dependent, eukaryotic)|interpro:IPR019818|interpro:IPR024084|rcsb pdb:1T09|rcsb pdb:1T0L|rcsb pdb:3INM|rcsb pdb:3MAP|rcsb pdb:3MAR|rcsb pdb:3MAS|rcsb pdb:4I3K|go:"GO:0060696"(regulation of phospholipid catabolic process)|rcsb pdb:4I3L|rcsb pdb:4KZO|rcsb pdb:4L03|rcsb pdb:4L04|rcsb pdb:4L06|rcsb pdb:4UMX|rcsb pdb:4UMY|rcsb pdb:4XRX|rcsb pdb:4XS3|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006097"(glyoxylate cycle)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006102"(isocitrate metabolic process)|go:"GO:0006103"(2-oxoglutarate metabolic process)|go:"GO:0006739"(NADP metabolic process)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008585"(female gonad development)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|ensembl:ENST00000345146(transcript)|go:"GO:0045296"(cadherin binding)|ensembl:ENST00000415913(transcript)|ensembl:ENST00000446179(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004450"("isocitrate dehydrogenase (NADP+) activity")|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0050661"(NADP binding)|go:"GO:0051287"(NAD binding)|rcsb pdb:5DE1|rcsb pdb:5GIR|rcsb pdb:5K10|rcsb pdb:5K11|rcsb pdb:5L57|rcsb pdb:5L58|rcsb pdb:5LGE|rcsb pdb:5SUN|rcsb pdb:5SVF|rcsb pdb:5TQH|rcsb pdb:5YFM|rcsb pdb:5YFN|rcsb pdb:6ADG|rcsb pdb:6B0Z|rcsb pdb:6BKX|rcsb pdb:6BKY|rcsb pdb:6BKZ|rcsb pdb:6BL0|rcsb pdb:6BL1|rcsb pdb:6BL2|rcsb pdb:6IO0|rcsb pdb:6VEI|rcsb pdb:6VG0|reactome:R-HSA-389542|reactome:R-HSA-6798695|reactome:R-HSA-2978092|rcsb pdb:6O2Y|rcsb pdb:6O2Z|rcsb pdb:6PAY|rcsb pdb:6Q6F|rcsb pdb:6U4J|reactome:R-HSA-9033241|dip:DIP-59311N	refseq:NP_005887.2|refseq:NP_001269315.1|refseq:NP_001269316.1|ensembl:ENSG00000138413(gene)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071071"(regulation of phospholipid biosynthetic process)|go:"GO:1904724"(tertiary granule lumen)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004790(Isocitrate dehydrogenase NADP-dependent, eukaryotic)|interpro:IPR019818|interpro:IPR024084|rcsb pdb:1T09|rcsb pdb:1T0L|rcsb pdb:3INM|rcsb pdb:3MAP|rcsb pdb:3MAR|rcsb pdb:3MAS|rcsb pdb:4I3K|go:"GO:0060696"(regulation of phospholipid catabolic process)|rcsb pdb:4I3L|rcsb pdb:4KZO|rcsb pdb:4L03|rcsb pdb:4L04|rcsb pdb:4L06|rcsb pdb:4UMX|rcsb pdb:4UMY|rcsb pdb:4XRX|rcsb pdb:4XS3|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006097"(glyoxylate cycle)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006102"(isocitrate metabolic process)|go:"GO:0006103"(2-oxoglutarate metabolic process)|go:"GO:0006739"(NADP metabolic process)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008585"(female gonad development)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|ensembl:ENST00000345146(transcript)|go:"GO:0045296"(cadherin binding)|ensembl:ENST00000415913(transcript)|ensembl:ENST00000446179(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004450"("isocitrate dehydrogenase (NADP+) activity")|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0050661"(NADP binding)|go:"GO:0051287"(NAD binding)|rcsb pdb:5DE1|rcsb pdb:5GIR|rcsb pdb:5K10|rcsb pdb:5K11|rcsb pdb:5L57|rcsb pdb:5L58|rcsb pdb:5LGE|rcsb pdb:5SUN|rcsb pdb:5SVF|rcsb pdb:5TQH|rcsb pdb:5YFM|rcsb pdb:5YFN|rcsb pdb:6ADG|rcsb pdb:6B0Z|rcsb pdb:6BKX|rcsb pdb:6BKY|rcsb pdb:6BKZ|rcsb pdb:6BL0|rcsb pdb:6BL1|rcsb pdb:6BL2|rcsb pdb:6IO0|rcsb pdb:6VEI|rcsb pdb:6VG0|reactome:R-HSA-389542|reactome:R-HSA-6798695|reactome:R-HSA-2978092|rcsb pdb:6O2Y|rcsb pdb:6O2Z|rcsb pdb:6PAY|rcsb pdb:6Q6F|rcsb pdb:6U4J|reactome:R-HSA-9033241|dip:DIP-59311N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:562(ecolx)|taxid:562(Escherichia coli)	-	2017/08/06	2017/08/10	rogid:RFBziMEb70PKCzUCJm2jd40y44M9606	rogid:RFBziMEb70PKCzUCJm2jd40y44M9606	rigid:+IlXPYZxOXfGwAFEkfCngrMWnJ8	false	-	-	-	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)