#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P0C6U8	uniprotkb:P62753	intact:EBI-15810860|uniprotkb:P59641	intact:EBI-356625|uniprotkb:P08227|uniprotkb:P10660|uniprotkb:Q4VBY7|uniprotkb:Q8N6Z7|ensembl:ENSP00000369757	psi-mi:r1a_sars(display_long)|uniprotkb:ORF1a polyprotein(gene name synonym)|uniprotkb:1a(orf name)	psi-mi:rs6_human(display_long)|uniprotkb:RPS6(gene name)|psi-mi:RPS6(display_short)|uniprotkb:Phosphoprotein NP33(gene name synonym)|uniprotkb:Small ribosomal subunit protein eS6(gene name synonym)|uniprotkb:OK/SW-cl.2(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Kamitani et al. (2009)	pubmed:19838190|doi:10.1038/nsmb.1680|imex:IM-14322	taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15811015|imex:IM-14322-1|dip:DIP-103228E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0002151"(G-quadruplex RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004519"(endonuclease activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016540"(protein autoprocessing)|go:"GO:0019079"(viral genome replication)|go:"GO:0019082"(viral protein processing)|go:"GO:0019083"(viral transcription)|go:"GO:0019785"(ISG15-specific protease activity)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039519"(modulation by virus of host autophagy)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039547"(suppression by virus of host TRAF activity)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039579"(suppression by virus of host ISG15-protein conjugation)|go:"GO:0039595"(induction by virus of catabolism of host mRNA)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|go:"GO:0039648"(modulation by virus of host protein ubiquitination)|go:"GO:0039690"(positive stranded viral RNA replication)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0039714"(cytoplasmic viral factory)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0062243"(double membrane vesicle viral factory outer membrane)|go:"GO:0070536"(protein K63-linked deubiquitination)|go:"GO:0071108"(protein K48-linked deubiquitination)|interpro:IPR002589(Appr-1-p processing)|interpro:IPR008740(Peptidase C30, Coronavirus endopeptidase)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR013016(Peptidase C30/C16)|interpro:IPR014822(Nsp9 replicase)|interpro:IPR014828(Nsp7 replicase)|interpro:IPR014829(Nsp8 replicase)|interpro:IPR018995|interpro:IPR021590|interpro:IPR022733|interpro:IPR024358|interpro:IPR024375|interpro:IPR032505|interpro:IPR032592|interpro:IPR036333|interpro:IPR036499|interpro:IPR037204|interpro:IPR037230|interpro:IPR038030|interpro:IPR038083|interpro:IPR038123|interpro:IPR038166|interpro:IPR038400|interpro:IPR042570|interpro:IPR043177|interpro:IPR043178|interpro:IPR043472|interpro:IPR043477|interpro:IPR043478|interpro:IPR043503|interpro:IPR043504|interpro:IPR043610|interpro:IPR043611|interpro:IPR043612|interpro:IPR043613|interpro:IPR043615|interpro:IPR044353|interpro:IPR044357|interpro:IPR044367|interpro:IPR044371|interpro:IPR044374|interpro:IPR044389|rcsb pdb:1P76|rcsb pdb:1P9T|rcsb pdb:1PA5|rcsb pdb:1PUK|go:"GO:0039604"(suppression by virus of host translation)|rcsb pdb:1Q1X|rcsb pdb:1Q2W|rcsb pdb:1QZ8|rcsb pdb:1UJ1|rcsb pdb:1UK3|rcsb pdb:1UK4|rcsb pdb:1UW7|rcsb pdb:1WOF|rcsb pdb:1YSY|rcsb pdb:1Z1I|rcsb pdb:1Z1J|rcsb pdb:2A5A|rcsb pdb:2A5I|rcsb pdb:2A5K|rcsb pdb:2ACF|rcsb pdb:2AHM|rcsb pdb:2AJ5|rcsb pdb:2ALV|rcsb pdb:2AMD|rcsb pdb:2AMQ|rcsb pdb:2BX3|rcsb pdb:2BX4|rcsb pdb:2C3S|rcsb pdb:2D2D|rcsb pdb:2DUC|rcsb pdb:2FAV|rcsb pdb:2FE8|rcsb pdb:2FYG|rcsb pdb:2G9T|rcsb pdb:2GA6|rcsb pdb:2GDT|rcsb pdb:2GRI|rcsb pdb:2GT7|rcsb pdb:2GT8|rcsb pdb:2GTB|rcsb pdb:2GX4|rcsb pdb:2GZ7|rcsb pdb:2GZ8|rcsb pdb:2GZ9|rcsb pdb:2H2Z|rcsb pdb:2HOB|rcsb pdb:2HSX|rcsb pdb:2IDY|rcsb pdb:2KAF|rcsb pdb:2KQV|rcsb pdb:2KQW|rcsb pdb:2KYS|rcsb pdb:2LIZ|rcsb pdb:2OP9|rcsb pdb:2PWX|rcsb pdb:2W2G|rcsb pdb:2WCT|rcsb pdb:2Z3C|rcsb pdb:2Z3D|rcsb pdb:2Z3E|rcsb pdb:2ZU4|rcsb pdb:2ZU5|rcsb pdb:3ATW|rcsb pdb:3AVZ|rcsb pdb:3AW0|rcsb pdb:3AW1|rcsb pdb:3E91|rcsb pdb:3EA7|rcsb pdb:3EA8|rcsb pdb:3EA9|rcsb pdb:3EAJ|rcsb pdb:3EE7|rcsb pdb:3F9E|rcsb pdb:3F9F|rcsb pdb:3F9G|rcsb pdb:3F9H|rcsb pdb:3FZD|rcsb pdb:3IWM|rcsb pdb:3M3S|rcsb pdb:3M3T|rcsb pdb:3M3V|rcsb pdb:3MJ5|rcsb pdb:3R24|rcsb pdb:3SN8|rcsb pdb:3SNA|rcsb pdb:3SNB|rcsb pdb:3SNC|rcsb pdb:3SND|rcsb pdb:3SNE|rcsb pdb:1UK2|rcsb pdb:3SZN|rcsb pdb:3TIT|rcsb pdb:3TIU|rcsb pdb:3TNS|rcsb pdb:3TNT|rcsb pdb:3V3M|rcsb pdb:3VB3|rcsb pdb:3VB4|rcsb pdb:3VB5|rcsb pdb:3VB6|rcsb pdb:3VB7|rcsb pdb:4HI3|rcsb pdb:4M0W|rcsb pdb:4MDS|rcsb pdb:4MM3|rcsb pdb:4OVZ|rcsb pdb:4OW0|rcsb pdb:5F22|rcsb pdb:5Y3E|rcsb pdb:5Y3Q|rcsb pdb:6LNY|rcsb pdb:6NUR|rcsb pdb:6NUS|rcsb pdb:6W2A|rcsb pdb:6XHL|rcsb pdb:6XHN|rcsb pdb:6XHO|rcsb pdb:6Y7M|rcsb pdb:6YXJ|rcsb pdb:6LO0|reactome:R-HSA-9679504|reactome:R-HSA-9682706|reactome:R-HSA-9682708|reactome:R-HSA-9683439|reactome:R-HSA-9684325|dip:DIP-48580N	refseq:NP_001001.2|reactome:R-HSA-166208|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6790901|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|interpro:IPR014401(Ribosomal protein S6, eukaryotic)|interpro:IPR018282|mint:P62753|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6F4P|rcsb pdb:6F4Q|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|ensembl:ENSG00000137154(gene)|ensembl:ENST00000380394(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0001890"(placenta development)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0002309"(T cell proliferation involved in immune response)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0006924"(activation-induced cell death of T cells)|go:"GO:0007369"(gastrulation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022605"(mammalian oogenesis stage)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0030425"(dendrite)|go:"GO:0031929"(TOR signaling)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044297"(cell body)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048821"(erythrocyte development)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001377(Ribosomal protein S6e)|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|dip:DIP-31507N	psi-mi:"MI:0465"(dip)	-	-	dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/06	2020/03/30	rogid:zwPSRRjRlqC4IBqawJVQzY4HMGs694009	rogid:beDuXCIqL99V9JlVfpzx7MdpH689606	rigid:0jIfxz2kc9Df8zHzk5DTCbE3jLo	false	mutation disrupting interaction:165-165,164-164|myc tag:c-c|his tag:c-c	-	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)