#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P9WQN5 uniprotkb:P9WQN5 intact:EBI-7241067|uniprotkb:P63345|uniprotkb:L0T8W3|uniprotkb:O33250|intact:MINT-7262409|uniprotkb:Q0G9Y7 intact:EBI-7241067|uniprotkb:P63345|uniprotkb:L0T8W3|uniprotkb:O33250|intact:MINT-7262409|uniprotkb:Q0G9Y7 psi-mi:arc_myctu(display_long)|uniprotkb:AAA ATPase forming ring-shaped complexes(gene name synonym)|uniprotkb:Mycobacterial proteasome ATPase(gene name synonym)|uniprotkb:MTCY261.11c(orf name)|uniprotkb:Rv2115c(locus name)|uniprotkb:mpa(gene name)|psi-mi:mpa(display_short) psi-mi:arc_myctu(display_long)|uniprotkb:AAA ATPase forming ring-shaped complexes(gene name synonym)|uniprotkb:Mycobacterial proteasome ATPase(gene name synonym)|uniprotkb:MTCY261.11c(orf name)|uniprotkb:Rv2115c(locus name)|uniprotkb:mpa(gene name)|psi-mi:mpa(display_short) psi-mi:"MI:0071"(molecular sieving) Wang et al. (2009) pubmed:19836337|doi:10.1016/j.str.2009.08.010|imex:IM-11743 taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)") taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15810143|imex:IM-11743-1|dip:DIP-102505E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:P9WQN5|interpro:IPR027417|refseq:NP_216631.1|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR022482|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|refseq:WP_003411035.1|interpro:IPR032501|go:"GO:0005524"(ATP binding)|go:"GO:0005618"(cell wall)|go:"GO:0005886"(plasma membrane)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0022623"(proteasome-activating nucleotidase complex)|go:"GO:0030682"(mitigation of host defenses by symbiont)|go:"GO:0042802"(identical protein binding)|go:"GO:0043335"(protein unfolding)|go:"GO:0051409"(response to nitrosative stress)|go:"GO:0070628"(proteasome binding)|go:"GO:0071732"(cellular response to nitric oxide)|go:"GO:0140035"(ubiquitination-like modification-dependent protein binding)|rcsb pdb:3FP9|rcsb pdb:3M91|rcsb pdb:3M9B|rcsb pdb:3M9D|rcsb pdb:3M9H|rcsb pdb:5KWA|rcsb pdb:5KZF|interpro:IPR041626 mint:P9WQN5|interpro:IPR027417|refseq:NP_216631.1|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR022482|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|refseq:WP_003411035.1|interpro:IPR032501|go:"GO:0005524"(ATP binding)|go:"GO:0005618"(cell wall)|go:"GO:0005886"(plasma membrane)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0022623"(proteasome-activating nucleotidase complex)|go:"GO:0030682"(mitigation of host defenses by symbiont)|go:"GO:0042802"(identical protein binding)|go:"GO:0043335"(protein unfolding)|go:"GO:0051409"(response to nitrosative stress)|go:"GO:0070628"(proteasome binding)|go:"GO:0071732"(cellular response to nitric oxide)|go:"GO:0140035"(ubiquitination-like modification-dependent protein binding)|rcsb pdb:3FP9|rcsb pdb:3M91|rcsb pdb:3M9B|rcsb pdb:3M9D|rcsb pdb:3M9H|rcsb pdb:5KWA|rcsb pdb:5KZF|interpro:IPR041626 psi-mi:"MI:0465"(dip) caution:This sequence has been withdrawn from Uniprot.|crc64:4D5F4E630614C58D|comment:mint caution:This sequence has been withdrawn from Uniprot.|crc64:4D5F4E630614C58D|comment:mint full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/06 2017/08/10 rogid:Q6UC3UZX5LPgTadMYDrPO/HBW+Y83332 rogid:Q6UC3UZX5LPgTadMYDrPO/HBW+Y83332 rigid:uH+PqOlN5AlIR+PiI4afhgTh3qE false sufficient binding region:97-245|mutation disrupting interaction:235-235,187-187,173-173 sufficient binding region:97-245|mutation disrupting interaction:235-235,187-187,173-173 - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P9WQN5 uniprotkb:P9WQN5 intact:EBI-7241067|uniprotkb:P63345|uniprotkb:L0T8W3|uniprotkb:O33250|intact:MINT-7262409|uniprotkb:Q0G9Y7 intact:EBI-7241067|uniprotkb:P63345|uniprotkb:L0T8W3|uniprotkb:O33250|intact:MINT-7262409|uniprotkb:Q0G9Y7 psi-mi:arc_myctu(display_long)|uniprotkb:AAA ATPase forming ring-shaped complexes(gene name synonym)|uniprotkb:Mycobacterial proteasome ATPase(gene name synonym)|uniprotkb:MTCY261.11c(orf name)|uniprotkb:Rv2115c(locus name)|uniprotkb:mpa(gene name)|psi-mi:mpa(display_short) psi-mi:arc_myctu(display_long)|uniprotkb:AAA ATPase forming ring-shaped complexes(gene name synonym)|uniprotkb:Mycobacterial proteasome ATPase(gene name synonym)|uniprotkb:MTCY261.11c(orf name)|uniprotkb:Rv2115c(locus name)|uniprotkb:mpa(gene name)|psi-mi:mpa(display_short) psi-mi:"MI:0040"(electron microscopy) Wang et al. (2009) pubmed:19836337|doi:10.1016/j.str.2009.08.010|imex:IM-11743 taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)") taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15810189|imex:IM-11743-3|dip:DIP-102505E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:P9WQN5|interpro:IPR027417|refseq:NP_216631.1|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR022482|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|refseq:WP_003411035.1|interpro:IPR032501|go:"GO:0005524"(ATP binding)|go:"GO:0005618"(cell wall)|go:"GO:0005886"(plasma membrane)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0022623"(proteasome-activating nucleotidase complex)|go:"GO:0030682"(mitigation of host defenses by symbiont)|go:"GO:0042802"(identical protein binding)|go:"GO:0043335"(protein unfolding)|go:"GO:0051409"(response to nitrosative stress)|go:"GO:0070628"(proteasome binding)|go:"GO:0071732"(cellular response to nitric oxide)|go:"GO:0140035"(ubiquitination-like modification-dependent protein binding)|rcsb pdb:3FP9|rcsb pdb:3M91|rcsb pdb:3M9B|rcsb pdb:3M9D|rcsb pdb:3M9H|rcsb pdb:5KWA|rcsb pdb:5KZF|interpro:IPR041626 mint:P9WQN5|interpro:IPR027417|refseq:NP_216631.1|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR022482|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|refseq:WP_003411035.1|interpro:IPR032501|go:"GO:0005524"(ATP binding)|go:"GO:0005618"(cell wall)|go:"GO:0005886"(plasma membrane)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0022623"(proteasome-activating nucleotidase complex)|go:"GO:0030682"(mitigation of host defenses by symbiont)|go:"GO:0042802"(identical protein binding)|go:"GO:0043335"(protein unfolding)|go:"GO:0051409"(response to nitrosative stress)|go:"GO:0070628"(proteasome binding)|go:"GO:0071732"(cellular response to nitric oxide)|go:"GO:0140035"(ubiquitination-like modification-dependent protein binding)|rcsb pdb:3FP9|rcsb pdb:3M91|rcsb pdb:3M9B|rcsb pdb:3M9D|rcsb pdb:3M9H|rcsb pdb:5KWA|rcsb pdb:5KZF|interpro:IPR041626 psi-mi:"MI:0465"(dip) caution:This sequence has been withdrawn from Uniprot.|crc64:4D5F4E630614C58D|comment:mint caution:This sequence has been withdrawn from Uniprot.|crc64:4D5F4E630614C58D|comment:mint full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/06 2017/08/10 rogid:Q6UC3UZX5LPgTadMYDrPO/HBW+Y83332 rogid:Q6UC3UZX5LPgTadMYDrPO/HBW+Y83332 rigid:uH+PqOlN5AlIR+PiI4afhgTh3qE false sufficient binding region:97-245|mutation disrupting interaction:235-235,187-187,173-173 sufficient binding region:97-245|mutation disrupting interaction:235-235,187-187,173-173 - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P9WQN5 uniprotkb:P9WQN5 intact:EBI-7241067|uniprotkb:P63345|uniprotkb:L0T8W3|uniprotkb:O33250|intact:MINT-7262409|uniprotkb:Q0G9Y7 intact:EBI-7241067|uniprotkb:P63345|uniprotkb:L0T8W3|uniprotkb:O33250|intact:MINT-7262409|uniprotkb:Q0G9Y7 psi-mi:arc_myctu(display_long)|uniprotkb:AAA ATPase forming ring-shaped complexes(gene name synonym)|uniprotkb:Mycobacterial proteasome ATPase(gene name synonym)|uniprotkb:MTCY261.11c(orf name)|uniprotkb:Rv2115c(locus name)|uniprotkb:mpa(gene name)|psi-mi:mpa(display_short) psi-mi:arc_myctu(display_long)|uniprotkb:AAA ATPase forming ring-shaped complexes(gene name synonym)|uniprotkb:Mycobacterial proteasome ATPase(gene name synonym)|uniprotkb:MTCY261.11c(orf name)|uniprotkb:Rv2115c(locus name)|uniprotkb:mpa(gene name)|psi-mi:mpa(display_short) psi-mi:"MI:0404"(comigration in non denaturing gel electrophoresis) Wang et al. (2009) pubmed:19836337|doi:10.1016/j.str.2009.08.010|imex:IM-11743 taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)") taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15810166|imex:IM-11743-2|dip:DIP-102505E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:P9WQN5|interpro:IPR027417|refseq:NP_216631.1|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR022482|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|refseq:WP_003411035.1|interpro:IPR032501|go:"GO:0005524"(ATP binding)|go:"GO:0005618"(cell wall)|go:"GO:0005886"(plasma membrane)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0022623"(proteasome-activating nucleotidase complex)|go:"GO:0030682"(mitigation of host defenses by symbiont)|go:"GO:0042802"(identical protein binding)|go:"GO:0043335"(protein unfolding)|go:"GO:0051409"(response to nitrosative stress)|go:"GO:0070628"(proteasome binding)|go:"GO:0071732"(cellular response to nitric oxide)|go:"GO:0140035"(ubiquitination-like modification-dependent protein binding)|rcsb pdb:3FP9|rcsb pdb:3M91|rcsb pdb:3M9B|rcsb pdb:3M9D|rcsb pdb:3M9H|rcsb pdb:5KWA|rcsb pdb:5KZF|interpro:IPR041626 mint:P9WQN5|interpro:IPR027417|refseq:NP_216631.1|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR022482|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|refseq:WP_003411035.1|interpro:IPR032501|go:"GO:0005524"(ATP binding)|go:"GO:0005618"(cell wall)|go:"GO:0005886"(plasma membrane)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0022623"(proteasome-activating nucleotidase complex)|go:"GO:0030682"(mitigation of host defenses by symbiont)|go:"GO:0042802"(identical protein binding)|go:"GO:0043335"(protein unfolding)|go:"GO:0051409"(response to nitrosative stress)|go:"GO:0070628"(proteasome binding)|go:"GO:0071732"(cellular response to nitric oxide)|go:"GO:0140035"(ubiquitination-like modification-dependent protein binding)|rcsb pdb:3FP9|rcsb pdb:3M91|rcsb pdb:3M9B|rcsb pdb:3M9D|rcsb pdb:3M9H|rcsb pdb:5KWA|rcsb pdb:5KZF|interpro:IPR041626 psi-mi:"MI:0465"(dip) caution:This sequence has been withdrawn from Uniprot.|crc64:4D5F4E630614C58D|comment:mint caution:This sequence has been withdrawn from Uniprot.|crc64:4D5F4E630614C58D|comment:mint full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/06 2017/08/10 rogid:Q6UC3UZX5LPgTadMYDrPO/HBW+Y83332 rogid:Q6UC3UZX5LPgTadMYDrPO/HBW+Y83332 rigid:uH+PqOlN5AlIR+PiI4afhgTh3qE false sufficient binding region:97-245|mutation disrupting interaction:235-235,187-187,173-173 sufficient binding region:97-245|mutation disrupting interaction:235-235,187-187,173-173 - 0 psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:P9WQN5 uniprotkb:P9WQN5 intact:EBI-7241067|uniprotkb:P63345|uniprotkb:L0T8W3|uniprotkb:O33250|intact:MINT-7262409|uniprotkb:Q0G9Y7 intact:EBI-7241067|uniprotkb:P63345|uniprotkb:L0T8W3|uniprotkb:O33250|intact:MINT-7262409|uniprotkb:Q0G9Y7 psi-mi:arc_myctu(display_long)|uniprotkb:AAA ATPase forming ring-shaped complexes(gene name synonym)|uniprotkb:Mycobacterial proteasome ATPase(gene name synonym)|uniprotkb:MTCY261.11c(orf name)|uniprotkb:Rv2115c(locus name)|uniprotkb:mpa(gene name)|psi-mi:mpa(display_short) psi-mi:arc_myctu(display_long)|uniprotkb:AAA ATPase forming ring-shaped complexes(gene name synonym)|uniprotkb:Mycobacterial proteasome ATPase(gene name synonym)|uniprotkb:MTCY261.11c(orf name)|uniprotkb:Rv2115c(locus name)|uniprotkb:mpa(gene name)|psi-mi:mpa(display_short) psi-mi:"MI:0114"(x-ray crystallography) Wang et al. (2009) pubmed:19836337|doi:10.1016/j.str.2009.08.010|imex:IM-11743 taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)") taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15810213|imex:IM-11743-4|dip:DIP-102505E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:P9WQN5|interpro:IPR027417|refseq:NP_216631.1|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR022482|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|refseq:WP_003411035.1|interpro:IPR032501|go:"GO:0005524"(ATP binding)|go:"GO:0005618"(cell wall)|go:"GO:0005886"(plasma membrane)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0022623"(proteasome-activating nucleotidase complex)|go:"GO:0030682"(mitigation of host defenses by symbiont)|go:"GO:0042802"(identical protein binding)|go:"GO:0043335"(protein unfolding)|go:"GO:0051409"(response to nitrosative stress)|go:"GO:0070628"(proteasome binding)|go:"GO:0071732"(cellular response to nitric oxide)|go:"GO:0140035"(ubiquitination-like modification-dependent protein binding)|rcsb pdb:3FP9|rcsb pdb:3M91|rcsb pdb:3M9B|rcsb pdb:3M9D|rcsb pdb:3M9H|rcsb pdb:5KWA|rcsb pdb:5KZF|interpro:IPR041626 mint:P9WQN5|interpro:IPR027417|refseq:NP_216631.1|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR022482|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|refseq:WP_003411035.1|interpro:IPR032501|go:"GO:0005524"(ATP binding)|go:"GO:0005618"(cell wall)|go:"GO:0005886"(plasma membrane)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0022623"(proteasome-activating nucleotidase complex)|go:"GO:0030682"(mitigation of host defenses by symbiont)|go:"GO:0042802"(identical protein binding)|go:"GO:0043335"(protein unfolding)|go:"GO:0051409"(response to nitrosative stress)|go:"GO:0070628"(proteasome binding)|go:"GO:0071732"(cellular response to nitric oxide)|go:"GO:0140035"(ubiquitination-like modification-dependent protein binding)|rcsb pdb:3FP9|rcsb pdb:3M91|rcsb pdb:3M9B|rcsb pdb:3M9D|rcsb pdb:3M9H|rcsb pdb:5KWA|rcsb pdb:5KZF|interpro:IPR041626 psi-mi:"MI:0465"(dip) caution:This sequence has been withdrawn from Uniprot.|crc64:4D5F4E630614C58D|comment:mint caution:This sequence has been withdrawn from Uniprot.|crc64:4D5F4E630614C58D|comment:mint full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/06 2017/08/10 rogid:Q6UC3UZX5LPgTadMYDrPO/HBW+Y83332 rogid:Q6UC3UZX5LPgTadMYDrPO/HBW+Y83332 rigid:uH+PqOlN5AlIR+PiI4afhgTh3qE false binding-associated region:97-245 binding-associated region:97-245 - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)