#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q9X181	uniprotkb:Q9X180	intact:EBI-15810022|ensemblbacteria:AAD36430|uniprotkb:G4FF96	intact:EBI-15809993|ensemblbacteria:AAD36429|uniprotkb:G4FF95	psi-mi:q9x181_thema(display_long)|uniprotkb:TM_1360(locus name)	psi-mi:q9x180_thema(display_long)|uniprotkb:TM_1359(locus name)	psi-mi:"MI:0434"(phosphatase assay)	Yamada et al. (2009)	pubmed:19836334|doi:10.1016/j.str.2009.07.016|imex:IM-11742	taxid:243274(thema)|taxid:243274("Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)")	taxid:243274(thema)|taxid:243274("Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)")	psi-mi:"MI:0203"(dephosphorylation reaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15810039|imex:IM-11742-1|dip:DIP-102504E	-	-	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblbacteria:AAD36430(transcript)|ensemblbacteria:TM_1360(gene)|go:"GO:0000156"(phosphorelay response regulator activity)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0005829"(cytosol)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0046872"(metal ion binding)|interpro:IPR001789(Signal transduction response regulator, receiver region)|interpro:IPR011006(CheY-like)|interpro:IPR039420|rcsb pdb:3A0R|rcsb pdb:3A0U|rcsb pdb:3A10|refseq:NP_229161.1|refseq:WP_004081556.1|dip:DIP-48291N	ensemblbacteria:AAD36429(transcript)|ensemblbacteria:TM_1359(gene)|go:"GO:0000155"(phosphorelay sensor kinase activity)|go:"GO:0000166"(nucleotide binding)|go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR000014(PAS)|interpro:IPR003018(GAF)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR003661(Signal transduction histidine kinase, subgroup 1, dimerisation and phosphoacceptor region)|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036097|interpro:IPR036890|rcsb pdb:3A0R|rcsb pdb:3A0S|rcsb pdb:3A0T|rcsb pdb:3A0V|rcsb pdb:3A0W|rcsb pdb:3A0X|rcsb pdb:3A0Y|rcsb pdb:3A0Z|refseq:NP_229160.1|refseq:WP_004081555.1|dip:DIP-48290N	psi-mi:"MI:0465"(dip)	crc64:145302A42E89EB78	crc64:61D11F4FDC4D0E9E	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/06	2017/08/10	rogid:0CITRsTcs+1I2PM0j3MAwqoYS9I243274	rogid:OGg90YxKVwWK/idX5etn3dYkk84243274	rigid:KweqRdp/Jn4rpIP/CAbGEs2r53o	false	-	sufficient binding region:408-755	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9X181	uniprotkb:Q9X180	intact:EBI-15810022|ensemblbacteria:AAD36430|uniprotkb:G4FF96	intact:EBI-15809993|ensemblbacteria:AAD36429|uniprotkb:G4FF95	psi-mi:q9x181_thema(display_long)|uniprotkb:TM_1360(locus name)	psi-mi:q9x180_thema(display_long)|uniprotkb:TM_1359(locus name)	psi-mi:"MI:0424"(protein kinase assay)	Yamada et al. (2009)	pubmed:19836334|doi:10.1016/j.str.2009.07.016|imex:IM-11742	taxid:243274(thema)|taxid:243274("Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)")	taxid:243274(thema)|taxid:243274("Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)")	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15810077|imex:IM-11742-3|dip:DIP-102504E	-	-	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblbacteria:AAD36430(transcript)|ensemblbacteria:TM_1360(gene)|go:"GO:0000156"(phosphorelay response regulator activity)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0005829"(cytosol)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0046872"(metal ion binding)|interpro:IPR001789(Signal transduction response regulator, receiver region)|interpro:IPR011006(CheY-like)|interpro:IPR039420|rcsb pdb:3A0R|rcsb pdb:3A0U|rcsb pdb:3A10|refseq:NP_229161.1|refseq:WP_004081556.1|dip:DIP-48291N	ensemblbacteria:AAD36429(transcript)|ensemblbacteria:TM_1359(gene)|go:"GO:0000155"(phosphorelay sensor kinase activity)|go:"GO:0000166"(nucleotide binding)|go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR000014(PAS)|interpro:IPR003018(GAF)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR003661(Signal transduction histidine kinase, subgroup 1, dimerisation and phosphoacceptor region)|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036097|interpro:IPR036890|rcsb pdb:3A0R|rcsb pdb:3A0S|rcsb pdb:3A0T|rcsb pdb:3A0V|rcsb pdb:3A0W|rcsb pdb:3A0X|rcsb pdb:3A0Y|rcsb pdb:3A0Z|refseq:NP_229160.1|refseq:WP_004081555.1|dip:DIP-48290N	psi-mi:"MI:0465"(dip)	crc64:145302A42E89EB78	crc64:61D11F4FDC4D0E9E	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/06	2017/08/10	rogid:0CITRsTcs+1I2PM0j3MAwqoYS9I243274	rogid:OGg90YxKVwWK/idX5etn3dYkk84243274	rigid:KweqRdp/Jn4rpIP/CAbGEs2r53o	false	-	sufficient binding region:408-755	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9X181	uniprotkb:Q9X180	intact:EBI-15810022|ensemblbacteria:AAD36430|uniprotkb:G4FF96	intact:EBI-15809993|ensemblbacteria:AAD36429|uniprotkb:G4FF95	psi-mi:q9x181_thema(display_long)|uniprotkb:TM_1360(locus name)	psi-mi:q9x180_thema(display_long)|uniprotkb:TM_1359(locus name)	psi-mi:"MI:0114"(x-ray crystallography)	Yamada et al. (2009)	pubmed:19836334|doi:10.1016/j.str.2009.07.016|imex:IM-11742	taxid:243274(thema)|taxid:243274("Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)")	taxid:243274(thema)|taxid:243274("Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15810097|imex:IM-11742-4|dip:DIP-102504E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblbacteria:AAD36430(transcript)|ensemblbacteria:TM_1360(gene)|go:"GO:0000156"(phosphorelay response regulator activity)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0005829"(cytosol)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0046872"(metal ion binding)|interpro:IPR001789(Signal transduction response regulator, receiver region)|interpro:IPR011006(CheY-like)|interpro:IPR039420|rcsb pdb:3A0R|rcsb pdb:3A0U|rcsb pdb:3A10|refseq:NP_229161.1|refseq:WP_004081556.1|dip:DIP-48291N	ensemblbacteria:AAD36429(transcript)|ensemblbacteria:TM_1359(gene)|go:"GO:0000155"(phosphorelay sensor kinase activity)|go:"GO:0000166"(nucleotide binding)|go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR000014(PAS)|interpro:IPR003018(GAF)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR003661(Signal transduction histidine kinase, subgroup 1, dimerisation and phosphoacceptor region)|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036097|interpro:IPR036890|rcsb pdb:3A0R|rcsb pdb:3A0S|rcsb pdb:3A0T|rcsb pdb:3A0V|rcsb pdb:3A0W|rcsb pdb:3A0X|rcsb pdb:3A0Y|rcsb pdb:3A0Z|refseq:NP_229160.1|refseq:WP_004081555.1|dip:DIP-48290N	psi-mi:"MI:0465"(dip)	crc64:145302A42E89EB78	crc64:61D11F4FDC4D0E9E	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/06	2017/08/10	rogid:0CITRsTcs+1I2PM0j3MAwqoYS9I243274	rogid:OGg90YxKVwWK/idX5etn3dYkk84243274	rigid:KweqRdp/Jn4rpIP/CAbGEs2r53o	false	-	binding-associated region:408-755	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9X181	uniprotkb:Q9X180	intact:EBI-15810022|ensemblbacteria:AAD36430|uniprotkb:G4FF96	intact:EBI-15809993|ensemblbacteria:AAD36429|uniprotkb:G4FF95	psi-mi:q9x181_thema(display_long)|uniprotkb:TM_1360(locus name)	psi-mi:q9x180_thema(display_long)|uniprotkb:TM_1359(locus name)	psi-mi:"MI:0077"(nuclear magnetic resonance)	Yamada et al. (2009)	pubmed:19836334|doi:10.1016/j.str.2009.07.016|imex:IM-11742	taxid:243274(thema)|taxid:243274("Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)")	taxid:243274(thema)|taxid:243274("Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15810058|imex:IM-11742-2|dip:DIP-102504E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblbacteria:AAD36430(transcript)|ensemblbacteria:TM_1360(gene)|go:"GO:0000156"(phosphorelay response regulator activity)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0005829"(cytosol)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0046872"(metal ion binding)|interpro:IPR001789(Signal transduction response regulator, receiver region)|interpro:IPR011006(CheY-like)|interpro:IPR039420|rcsb pdb:3A0R|rcsb pdb:3A0U|rcsb pdb:3A10|refseq:NP_229161.1|refseq:WP_004081556.1|dip:DIP-48291N	ensemblbacteria:AAD36429(transcript)|ensemblbacteria:TM_1359(gene)|go:"GO:0000155"(phosphorelay sensor kinase activity)|go:"GO:0000166"(nucleotide binding)|go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR000014(PAS)|interpro:IPR003018(GAF)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR003661(Signal transduction histidine kinase, subgroup 1, dimerisation and phosphoacceptor region)|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036097|interpro:IPR036890|rcsb pdb:3A0R|rcsb pdb:3A0S|rcsb pdb:3A0T|rcsb pdb:3A0V|rcsb pdb:3A0W|rcsb pdb:3A0X|rcsb pdb:3A0Y|rcsb pdb:3A0Z|refseq:NP_229160.1|refseq:WP_004081555.1|dip:DIP-48290N	psi-mi:"MI:0465"(dip)	crc64:145302A42E89EB78	crc64:61D11F4FDC4D0E9E	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/06	2017/08/10	rogid:0CITRsTcs+1I2PM0j3MAwqoYS9I243274	rogid:OGg90YxKVwWK/idX5etn3dYkk84243274	rigid:KweqRdp/Jn4rpIP/CAbGEs2r53o	false	-	sufficient binding region:517-755	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9X181	uniprotkb:Q9X180	intact:EBI-15810022|ensemblbacteria:AAD36430|uniprotkb:G4FF96	intact:EBI-15809993|ensemblbacteria:AAD36429|uniprotkb:G4FF95	psi-mi:q9x181_thema(display_long)|uniprotkb:TM_1360(locus name)	psi-mi:q9x180_thema(display_long)|uniprotkb:TM_1359(locus name)	psi-mi:"MI:0841"(phosphotransferase assay)	Yamada et al. (2009)	pubmed:19836334|doi:10.1016/j.str.2009.07.016|imex:IM-11742	taxid:243274(thema)|taxid:243274("Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)")	taxid:243274(thema)|taxid:243274("Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)")	psi-mi:"MI:0844"(phosphotransfer reaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15810116|imex:IM-11742-5|dip:DIP-102504E	-	-	psi-mi:"MI:0843"(phosphate acceptor)	psi-mi:"MI:0842"(phosphate donor)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblbacteria:AAD36430(transcript)|ensemblbacteria:TM_1360(gene)|go:"GO:0000156"(phosphorelay response regulator activity)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0005829"(cytosol)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0046872"(metal ion binding)|interpro:IPR001789(Signal transduction response regulator, receiver region)|interpro:IPR011006(CheY-like)|interpro:IPR039420|rcsb pdb:3A0R|rcsb pdb:3A0U|rcsb pdb:3A10|refseq:NP_229161.1|refseq:WP_004081556.1|dip:DIP-48291N	ensemblbacteria:AAD36429(transcript)|ensemblbacteria:TM_1359(gene)|go:"GO:0000155"(phosphorelay sensor kinase activity)|go:"GO:0000166"(nucleotide binding)|go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR000014(PAS)|interpro:IPR003018(GAF)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR003661(Signal transduction histidine kinase, subgroup 1, dimerisation and phosphoacceptor region)|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036097|interpro:IPR036890|rcsb pdb:3A0R|rcsb pdb:3A0S|rcsb pdb:3A0T|rcsb pdb:3A0V|rcsb pdb:3A0W|rcsb pdb:3A0X|rcsb pdb:3A0Y|rcsb pdb:3A0Z|refseq:NP_229160.1|refseq:WP_004081555.1|dip:DIP-48290N	psi-mi:"MI:0465"(dip)	crc64:145302A42E89EB78	crc64:61D11F4FDC4D0E9E	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/06	2017/08/10	rogid:0CITRsTcs+1I2PM0j3MAwqoYS9I243274	rogid:OGg90YxKVwWK/idX5etn3dYkk84243274	rigid:KweqRdp/Jn4rpIP/CAbGEs2r53o	false	-	sufficient binding region:517-755	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)