#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q02959 uniprotkb:Q12416 intact:EBI-8484|uniprotkb:D6W3Q2|ensemblfungi:YPL116W intact:EBI-29963|uniprotkb:D6W2E5|ensemblfungi:YOR083W psi-mi:hos3_yeast(display_long)|uniprotkb:LPH11W(orf name)|uniprotkb:YPL116W(locus name)|uniprotkb:HOS3(gene name)|psi-mi:HOS3(display_short) psi-mi:whi5_yeast(display_long)|uniprotkb:WHI5(gene name)|psi-mi:WHI5(display_short)|uniprotkb:YOR3116W(orf name)|uniprotkb:YOR083W(locus name) psi-mi:"MI:0096"(pull down) Huang et al. (2009) pubmed:19823668|doi:10.1371/journal.pbio.1000188|imex:IM-14166 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15809586|imex:IM-14166-1|dip:DIP-102869E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015209.1|sgd:S000006037|dip:DIP-8047N|mint:Q02959|ensemblfungi:YPL116W(gene)|ensemblfungi:YPL116W_mRNA(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005628"(prospore membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005935"(cellular bud neck)|go:"GO:0016575"(histone deacetylation)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138 refseq:NP_014726.1|sgd:S000005609|dip:DIP-8958N|mint:Q12416|ensemblfungi:YOR083W(gene)|ensemblfungi:YOR083W_mRNA(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007089"(traversing start control point of mitotic cell cycle)|go:"GO:0008361"(regulation of cell size)|go:"GO:0009991"(response to extracellular stimulus)|go:"GO:0033309"(SBF transcription complex)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0071930"(negative regulation of transcription involved in G1/S transition of mitotic cell cycle)|interpro:IPR013734(Nrm1)|interpro:IPR039198 psi-mi:"MI:0465"(dip) crc64:F2B5D09E87B097E5 crc64:013A41AC5DC1975F full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/06 2017/08/10 rogid:ykbhTSaTI6X7Yq1I80wWzvb2sVk559292 rogid:Sz51DYEnxRj6Vuba1PxIAaTenV0559292 rigid:jCZKEPDvHeW44PpbMAgf6MpI8xM false tandem tag:c-c glutathione s tranferase tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q12477 uniprotkb:Q12416 intact:EBI-38090|uniprotkb:D6VRH3|ensemblfungi:YDL179W intact:EBI-29963|uniprotkb:D6W2E5|ensemblfungi:YOR083W psi-mi:pcl9_yeast(display_long)|uniprotkb:PCL9(gene name)|psi-mi:PCL9(display_short)|uniprotkb:D1408(orf name)|uniprotkb:YDL179W(locus name) psi-mi:whi5_yeast(display_long)|uniprotkb:WHI5(gene name)|psi-mi:WHI5(display_short)|uniprotkb:YOR3116W(orf name)|uniprotkb:YOR083W(locus name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Huang et al. (2009) pubmed:19823668|doi:10.1371/journal.pbio.1000188|imex:IM-14166 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15809607|imex:IM-14166-2|dip:DIP-102867E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010102.1|sgd:S000002338|mint:Q12477|dip:DIP-1510N|ensemblfungi:YDL179W(gene)|ensemblfungi:YDL179W_mRNA(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0005634"(nucleus)|go:"GO:0005935"(cellular bud neck)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032878"(regulation of establishment or maintenance of cell polarity)|go:"GO:0051301"(cell division)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR012104(Cyclin, fungal Pcl/HCS26)|interpro:IPR013763(Cyclin-related)|interpro:IPR036915 refseq:NP_014726.1|sgd:S000005609|dip:DIP-8958N|mint:Q12416|ensemblfungi:YOR083W(gene)|ensemblfungi:YOR083W_mRNA(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007089"(traversing start control point of mitotic cell cycle)|go:"GO:0008361"(regulation of cell size)|go:"GO:0009991"(response to extracellular stimulus)|go:"GO:0033309"(SBF transcription complex)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0071930"(negative regulation of transcription involved in G1/S transition of mitotic cell cycle)|interpro:IPR013734(Nrm1)|interpro:IPR039198 psi-mi:"MI:0465"(dip) crc64:183820067EC00D23 crc64:013A41AC5DC1975F full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/06 2017/08/10 rogid:OVVtpVr5OY+NyG7JT+AQ+4bJuDE559292 rogid:Sz51DYEnxRj6Vuba1PxIAaTenV0559292 rigid:un3wMhYOHW8ddZXYYCcp92GTPKo false ha tag:c-c myc tag:c-c - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P32561 uniprotkb:Q12416 intact:EBI-15864|uniprotkb:D6W0L7|ensemblfungi:YNL330C intact:EBI-29963|uniprotkb:D6W2E5|ensemblfungi:YOR083W psi-mi:rpd3_yeast(display_long)|uniprotkb:RPD3(gene name)|psi-mi:RPD3(display_short)|uniprotkb:SDI2(gene name synonym)|uniprotkb:YNL330C(locus name)|uniprotkb:N0305(orf name)|uniprotkb:MOF6(gene name synonym)|uniprotkb:REC3(gene name synonym)|uniprotkb:SDS6(gene name synonym)|uniprotkb:Transcriptional regulatory protein RPD3(gene name synonym) psi-mi:whi5_yeast(display_long)|uniprotkb:WHI5(gene name)|psi-mi:WHI5(display_short)|uniprotkb:YOR3116W(orf name)|uniprotkb:YOR083W(locus name) psi-mi:"MI:0096"(pull down) Huang et al. (2009) pubmed:19823668|doi:10.1371/journal.pbio.1000188|imex:IM-14166 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15809628|imex:IM-14166-3|dip:DIP-102870E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YNL330C(gene)|ensemblfungi:YNL330C_mRNA(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000117"(regulation of transcription involved in G2/M transition of mitotic cell cycle)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0016479"(negative regulation of transcription by RNA polymerase I)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0031939"(obsolete negative regulation of chromatin silencing at telomere)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032221"(Rpd3S/Clr6-CII complex)|go:"GO:0033698"(Rpd3L complex)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034503"(protein localization to nucleolar rDNA repeats)|go:"GO:0044804"(autophagy of nucleus)|go:"GO:0045128"(negative regulation of reciprocal meiotic recombination)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051038"(negative regulation of transcription involved in meiotic cell cycle)|go:"GO:0061186"(negative regulation of silent mating-type cassette heterochromatin assembly)|go:"GO:0061188"(negative regulation of ribosomal DNA heterochromatin assembly)|go:"GO:0061587"(transfer RNA gene-mediated silencing)|go:"GO:0070210"(Rpd3L-Expanded complex)|go:"GO:0070211"(Snt2C complex)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0070550"(rDNA condensation)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|reactome:R-SCE-3214815|reactome:R-SCE-4551638|reactome:R-SCE-9018519|go:"GO:0070822"(Sin3-type complex)|go:"GO:0070932"(histone H3 deacetylation)|refseq:NP_014069.1|sgd:S000005274|dip:DIP-681N|mint:P32561 refseq:NP_014726.1|sgd:S000005609|dip:DIP-8958N|mint:Q12416|ensemblfungi:YOR083W(gene)|ensemblfungi:YOR083W_mRNA(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007089"(traversing start control point of mitotic cell cycle)|go:"GO:0008361"(regulation of cell size)|go:"GO:0009991"(response to extracellular stimulus)|go:"GO:0033309"(SBF transcription complex)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0071930"(negative regulation of transcription involved in G1/S transition of mitotic cell cycle)|interpro:IPR013734(Nrm1)|interpro:IPR039198 psi-mi:"MI:0465"(dip) crc64:34FFD72A7E7425DB crc64:013A41AC5DC1975F full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/06 2017/08/10 rogid:GQ1xB56fpHiVV03yhoPADv04fl0559292 rogid:Sz51DYEnxRj6Vuba1PxIAaTenV0559292 rigid:zunFRSqHX1SKb2DkxyTukRnMqcQ false tandem tag:c-c glutathione s tranferase tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q12214 uniprotkb:Q12416 intact:EBI-8471|uniprotkb:D6W472|ensemblfungi:YPR068C intact:EBI-29963|uniprotkb:D6W2E5|ensemblfungi:YOR083W psi-mi:hos1_yeast(display_long)|uniprotkb:YP9499.23C(orf name)|uniprotkb:YPR068C(locus name)|uniprotkb:HOS1(gene name)|psi-mi:HOS1(display_short) psi-mi:whi5_yeast(display_long)|uniprotkb:WHI5(gene name)|psi-mi:WHI5(display_short)|uniprotkb:YOR3116W(orf name)|uniprotkb:YOR083W(locus name) psi-mi:"MI:0096"(pull down) Huang et al. (2009) pubmed:19823668|doi:10.1371/journal.pbio.1000188|imex:IM-14166 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15809649|imex:IM-14166-4|dip:DIP-102868E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015393.1|sgd:S000006272|dip:DIP-7974N|ensemblfungi:YPR068C(gene)|ensemblfungi:YPR068C_mRNA(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0034983"(peptidyl-lysine deacetylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061587"(transfer RNA gene-mediated silencing)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR023696|interpro:IPR023801 refseq:NP_014726.1|sgd:S000005609|dip:DIP-8958N|mint:Q12416|ensemblfungi:YOR083W(gene)|ensemblfungi:YOR083W_mRNA(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007089"(traversing start control point of mitotic cell cycle)|go:"GO:0008361"(regulation of cell size)|go:"GO:0009991"(response to extracellular stimulus)|go:"GO:0033309"(SBF transcription complex)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0071930"(negative regulation of transcription involved in G1/S transition of mitotic cell cycle)|interpro:IPR013734(Nrm1)|interpro:IPR039198 psi-mi:"MI:0465"(dip) crc64:5DCFF35D8F6AC87D crc64:013A41AC5DC1975F full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/06 2017/08/10 rogid:51A8VCXiJNqUYGQpNxjycMGXuQ4559292 rogid:Sz51DYEnxRj6Vuba1PxIAaTenV0559292 rigid:jJLSo63r+Uo6fhZEVTD1My73sVY false tandem tag:c-c glutathione s tranferase tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot)