#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P27695	uniprotkb:Q9UIF7	intact:EBI-1048805|uniprotkb:Q969L5|uniprotkb:Q99775|ensembl:ENSP00000216714|ensembl:ENSP00000381111|ensembl:ENSP00000451979	intact:EBI-725721|uniprotkb:Q15830|uniprotkb:Q9UBP2|uniprotkb:Q9UBS7|uniprotkb:Q9UIF4|uniprotkb:Q9UIF5|uniprotkb:Q9UIF6|uniprotkb:D3DPZ4|ensembl:ENSP00000361170|ensembl:ENSP00000500891	psi-mi:apex1_human(display_long)|uniprotkb:Apurinic-apyrimidinic endonuclease 1(gene name synonym)|uniprotkb:APEX nuclease(gene name synonym)|uniprotkb:APE1(gene name synonym)|uniprotkb:APEX1(gene name)|psi-mi:APEX1(display_short)|uniprotkb:APE(gene name synonym)|uniprotkb:APEX(gene name synonym)|uniprotkb:APX(gene name synonym)|uniprotkb:HAP1(gene name synonym)|uniprotkb:REF1(gene name synonym)|uniprotkb:REF-1(gene name synonym)|uniprotkb:Redox factor-1(gene name synonym)	psi-mi:mutyh_human(display_long)|uniprotkb:MutY homolog(gene name synonym)|uniprotkb:MUTYH(gene name)|psi-mi:MUTYH(display_short)|uniprotkb:MYH(gene name synonym)	psi-mi:"MI:0096"(pull down)	van et al. (2009)	pubmed:19820168|doi:10.1073/pnas.0907280106|imex:IM-14853	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15808651|imex:IM-14853-1|dip:DIP-71543E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001632.2|refseq:NP_542379.1|refseq:NP_542380.1|refseq:NP_001231178.1|ensembl:ENSG00000100823(gene)|ensembl:ENST00000216714(transcript)|ensembl:ENST00000398030(transcript)|ensembl:ENST00000555414(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003691"(double-stranded telomeric DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0004519"(endonuclease activity)|go:"GO:0004520"(endodeoxyribonuclease activity)|go:"GO:0004523"(RNA-DNA hybrid ribonuclease activity)|go:"GO:0004528"(phosphodiesterase I activity)|go:"GO:0004844"(uracil DNA N-glycosylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005840"(ribosome)|go:"GO:0006281"(DNA repair)|go:"GO:0006284"(base-excision repair)|go:"GO:0006287"(base-excision repair, gap-filling)|go:"GO:0006310"(DNA recombination)|go:"GO:0007568"(aging)|go:"GO:0008081"(phosphoric diester hydrolase activity)|go:"GO:0008309"(double-stranded DNA exodeoxyribonuclease activity)|go:"GO:0008311"(double-stranded DNA 3'-5' exodeoxyribonuclease activity)|go:"GO:0008408"(3'-5' exonuclease activity)|go:"GO:0014912"(negative regulation of smooth muscle cell migration)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0016607"(nuclear speck)|go:"GO:0016890"(site-specific endodeoxyribonuclease activity, specific for altered base)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0042493"|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0080111"(DNA demethylation)|go:"GO:0097698"(telomere maintenance via base-excision repair)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|interpro:IPR004808(Exodeoxyribonuclease III xth)|interpro:IPR005135(Endonuclease/exonuclease/phosphatase)|interpro:IPR020847|interpro:IPR020848|interpro:IPR036691|mint:P27695|rcsb pdb:1BIX|rcsb pdb:1CQG|rcsb pdb:1CQH|rcsb pdb:1DE8|rcsb pdb:1DE9|rcsb pdb:1DEW|rcsb pdb:1E9N|rcsb pdb:1HD7|rcsb pdb:2ISI|rcsb pdb:2O3H|rcsb pdb:3U8U|rcsb pdb:4IEM|rcsb pdb:4LND|rcsb pdb:4QH9|rcsb pdb:4QHD|rcsb pdb:4QHE|rcsb pdb:5CFG|rcsb pdb:5DFF|rcsb pdb:5DFH|rcsb pdb:5DFI|rcsb pdb:5DFJ|rcsb pdb:5DG0|rcsb pdb:5WN0|rcsb pdb:5WN1|rcsb pdb:5WN2|rcsb pdb:5WN3|rcsb pdb:5WN4|rcsb pdb:5WN5|rcsb pdb:6BOQ|rcsb pdb:6BOR|rcsb pdb:6BOS|rcsb pdb:6BOT|rcsb pdb:6BOU|rcsb pdb:6BOV|rcsb pdb:6BOW|rcsb pdb:6MK3|rcsb pdb:6MKK|rcsb pdb:6MKM|rcsb pdb:6MKO|rcsb pdb:6P93|rcsb pdb:6P94|rcsb pdb:6W0Q|rcsb pdb:6W2P|rcsb pdb:6W3L|rcsb pdb:6W3N|rcsb pdb:6W3Q|rcsb pdb:6W3U|rcsb pdb:6W43|rcsb pdb:6W4I|rcsb pdb:6W4T|reactome:R-HSA-110357|reactome:R-HSA-110362|reactome:R-HSA-110373|reactome:R-HSA-5651801|reactome:R-HSA-73930|reactome:R-HSA-73933|dip:DIP-6130N	refseq:NP_001041636.1|refseq:NP_001041637.1|refseq:NP_001041638.1|refseq:NP_001041639.1|refseq:NP_001121897.1|refseq:NP_036354.1|refseq:NP_001280119.1|refseq:NP_001280120.1|refseq:NP_001280121.1|refseq:NP_001280124.1|refseq:NP_001280125.1|refseq:XP_011539806.1|ensembl:ENSG00000132781(gene)|ensembl:ENST00000372098(transcript)|ensembl:ENST00000672818(transcript)|go:"GO:0000701"(purine-specific mismatch base pair DNA N-glycosylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006281"(DNA repair)|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-110357|reactome:R-HSA-9608287|reactome:R-HSA-9608290|rcsb pdb:3N5N|go:"GO:0006298"(mismatch repair)|go:"GO:0019104"(DNA N-glycosylase activity)|go:"GO:0032357"(oxidized purine DNA binding)|go:"GO:0032407"(MutSalpha complex binding)|go:"GO:0034039"(8-oxo-7,8-dihydroguanine DNA N-glycosylase activity)|go:"GO:0035485"(adenine/guanine mispair binding)|go:"GO:0045007"(depurination)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR000086(NUDIX hydrolase, core)|interpro:IPR000445(Helix-hairpin-helix motif)|interpro:IPR003265(HhH-GPD)|interpro:IPR003651(Iron-sulphur cluster loop)|interpro:IPR004035(Endonuclease III, iron-sulphur binding, conserved site-1)|interpro:IPR004036(Endonuclease III, conserved site-2)|interpro:IPR011257(DNA glycosylase)|interpro:IPR015797(NUDIX)|go:"GO:0006284"(base-excision repair)|interpro:IPR023170|interpro:IPR029119|interpro:IPR044298|rcsb pdb:1X51|refseq:XP_016856823.1|refseq:XP_016856824.1|dip:DIP-41972N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/06	2017/08/10	rogid:418z7Qhlcop0UKIfNQse+iyM8gg9606	rogid:8BA0RGqpcUQP96lX/n8/GuJxVRI9606	rigid:xyZZIC8NFFko6vzjj3iUlpSS1n0	false	-	glutathione s tranferase tag:n-n	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9UGP5	uniprotkb:Q9UIF7	intact:EBI-741859|uniprotkb:D3DR76|uniprotkb:Q5JQP5|uniprotkb:Q6NUM2|uniprotkb:Q9BTN8|uniprotkb:Q9HA10|uniprotkb:Q9HB35|ensembl:ENSP00000299206|ensembl:ENSP00000359181|ensembl:ENSP00000359188|intact:EBI-8047022|intact:MINT-3079892	intact:EBI-725721|uniprotkb:Q15830|uniprotkb:Q9UBP2|uniprotkb:Q9UBS7|uniprotkb:Q9UIF4|uniprotkb:Q9UIF5|uniprotkb:Q9UIF6|uniprotkb:D3DPZ4|ensembl:ENSP00000361170|ensembl:ENSP00000500891	psi-mi:dpoll_human(display_long)|uniprotkb:DNA polymerase beta-2(gene name synonym)|uniprotkb:DNA polymerase kappa(gene name synonym)|uniprotkb:POLL(gene name)|psi-mi:POLL(display_short)	psi-mi:mutyh_human(display_long)|uniprotkb:MutY homolog(gene name synonym)|uniprotkb:MUTYH(gene name)|psi-mi:MUTYH(display_short)|uniprotkb:MYH(gene name synonym)	psi-mi:"MI:0096"(pull down)	van et al. (2009)	pubmed:19820168|doi:10.1073/pnas.0907280106|imex:IM-14853	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15808670|imex:IM-14853-2|dip:DIP-104173E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001167555.1|refseq:NP_001167556.1|refseq:NP_037406.1|ensembl:ENSG00000166169(gene)|ensembl:ENST00000299206(transcript)|ensembl:ENST00000370162(transcript)|ensembl:ENST00000370169(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006287"(base-excision repair, gap-filling)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0016446"(somatic hypermutation of immunoglobulin genes)|go:"GO:0035861"(site of double-strand break)|go:"GO:0046872"(metal ion binding)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0071897"(DNA biosynthetic process)|interpro:IPR001357(BRCT)|interpro:IPR002008(DNA-directed DNA polymerase, family X, beta-like)|interpro:IPR002054(DNA-directed DNA polymerase, family X)|interpro:IPR010996(DNA-directed DNA polymerase, family X, beta-like, N-terminal)|interpro:IPR018944|interpro:IPR019843|interpro:IPR022312|rcsb pdb:2JW5|rcsb pdb:2PFN|interpro:IPR027421|rcsb pdb:2PFO|rcsb pdb:2PFP|rcsb pdb:2PFQ|rcsb pdb:3C5F|rcsb pdb:3C5G|rcsb pdb:3HW8|rcsb pdb:3HWT|rcsb pdb:3HX0|rcsb pdb:3MDA|rcsb pdb:3MDC|rcsb pdb:3MGH|interpro:IPR028207|rcsb pdb:3MGI|rcsb pdb:3PML|rcsb pdb:3PMN|rcsb pdb:3PNC|rcsb pdb:3UPQ|rcsb pdb:3UQ0|rcsb pdb:3UQ2|rcsb pdb:4FO6|rcsb pdb:4K4G|rcsb pdb:4K4H|rcsb pdb:4K4I|rcsb pdb:4X5V|rcsb pdb:4XA5|rcsb pdb:4XQ8|rcsb pdb:4XRH|rcsb pdb:4XUS|rcsb pdb:5CA7|rcsb pdb:5CB1|rcsb pdb:5CHG|rcsb pdb:5CJ7|rcsb pdb:5CP2|rcsb pdb:5CR0|rcsb pdb:5CWR|rcsb pdb:5DDM|rcsb pdb:5DDY|rcsb pdb:5DKW|rcsb pdb:5III|rcsb pdb:5IIJ|rcsb pdb:5IIK|rcsb pdb:5IIL|rcsb pdb:5IIM|rcsb pdb:5IIN|rcsb pdb:5IIO|rcsb pdb:5W4G|reactome:R-HSA-5693571|interpro:IPR029398|interpro:IPR036420|interpro:IPR037160|interpro:IPR043519|mint:Q9UGP5|rcsb pdb:1NZP|rcsb pdb:1RZT|rcsb pdb:1XSL|rcsb pdb:1XSN|rcsb pdb:1XSP|rcsb pdb:2BCQ|rcsb pdb:2BCR|rcsb pdb:2BCS|rcsb pdb:2BCU|rcsb pdb:2BCV|rcsb pdb:2GWS|refseq:NP_001295311.1|refseq:XP_011537953.1|refseq:XP_006717840.1|dip:DIP-48999N	refseq:NP_001041636.1|refseq:NP_001041637.1|refseq:NP_001041638.1|refseq:NP_001041639.1|refseq:NP_001121897.1|refseq:NP_036354.1|refseq:NP_001280119.1|refseq:NP_001280120.1|refseq:NP_001280121.1|refseq:NP_001280124.1|refseq:NP_001280125.1|refseq:XP_011539806.1|ensembl:ENSG00000132781(gene)|ensembl:ENST00000372098(transcript)|ensembl:ENST00000672818(transcript)|go:"GO:0000701"(purine-specific mismatch base pair DNA N-glycosylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006281"(DNA repair)|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-110357|reactome:R-HSA-9608287|reactome:R-HSA-9608290|rcsb pdb:3N5N|go:"GO:0006298"(mismatch repair)|go:"GO:0019104"(DNA N-glycosylase activity)|go:"GO:0032357"(oxidized purine DNA binding)|go:"GO:0032407"(MutSalpha complex binding)|go:"GO:0034039"(8-oxo-7,8-dihydroguanine DNA N-glycosylase activity)|go:"GO:0035485"(adenine/guanine mispair binding)|go:"GO:0045007"(depurination)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR000086(NUDIX hydrolase, core)|interpro:IPR000445(Helix-hairpin-helix motif)|interpro:IPR003265(HhH-GPD)|interpro:IPR003651(Iron-sulphur cluster loop)|interpro:IPR004035(Endonuclease III, iron-sulphur binding, conserved site-1)|interpro:IPR004036(Endonuclease III, conserved site-2)|interpro:IPR011257(DNA glycosylase)|interpro:IPR015797(NUDIX)|go:"GO:0006284"(base-excision repair)|interpro:IPR023170|interpro:IPR029119|interpro:IPR044298|rcsb pdb:1X51|refseq:XP_016856823.1|refseq:XP_016856824.1|dip:DIP-41972N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/06	2017/08/10	rogid:EzxrerLzDV6XU1Q+/fKcnoOU5Rc9606	rogid:8BA0RGqpcUQP96lX/n8/GuJxVRI9606	rigid:CTk4SppJ851SkFS5LQgVrUDVwM0	false	-	glutathione s tranferase tag:n-n	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)