#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:O15350	uniprotkb:O15350	intact:EBI-389606|uniprotkb:O15351|uniprotkb:Q17RN8|uniprotkb:Q5TBV5|uniprotkb:Q5TBV6|uniprotkb:Q8NHW9|uniprotkb:Q8TDY5|uniprotkb:Q8TDY6|uniprotkb:Q9NTK8|uniprotkb:B7Z9C1|uniprotkb:B7Z8Z1|uniprotkb:C9J521|uniprotkb:B7Z7J4|ensembl:ENSP00000367545	intact:EBI-389606|uniprotkb:O15351|uniprotkb:Q17RN8|uniprotkb:Q5TBV5|uniprotkb:Q5TBV6|uniprotkb:Q8NHW9|uniprotkb:Q8TDY5|uniprotkb:Q8TDY6|uniprotkb:Q9NTK8|uniprotkb:B7Z9C1|uniprotkb:B7Z8Z1|uniprotkb:C9J521|uniprotkb:B7Z7J4|ensembl:ENSP00000367545	psi-mi:p73_human(display_long)|uniprotkb:TP73(gene name)|psi-mi:TP73(display_short)|uniprotkb:P73(gene name synonym)|uniprotkb:p53-like transcription factor(gene name synonym)|uniprotkb:p53-related protein(gene name synonym)	psi-mi:p73_human(display_long)|uniprotkb:TP73(gene name)|psi-mi:TP73(display_short)|uniprotkb:P73(gene name synonym)|uniprotkb:p53-like transcription factor(gene name synonym)|uniprotkb:p53-related protein(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Joerger et al. (2009)	pubmed:19815500|doi:10.1073/pnas.0905867106|imex:IM-14849	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15808151|imex:IM-14849-1|dip:DIP-104163E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000346387|ensembl:ENSP00000340740|ensembl:ENST00000354437|ensembl:ENSP00000346423|ensembl:ENST00000357733|ensembl:ENSP00000350366|ensembl:ENST00000378285|ensembl:ENSP00000367534|ensembl:ENST00000378288|ensembl:ENSP00000367537|ensembl:ENST00000378290|ensembl:ENSP00000367539|ensembl:ENSP00000367545|ensembl:ENST00000603362|ensembl:ENSP00000474626|ensembl:ENST00000604074|ensembl:ENSP00000475143|ensembl:ENST00000604479|ensembl:ENSP00000474322|refseq:NP_001119712.1|refseq:NP_001119713.1|refseq:NP_001119714.1|refseq:NP_001191113.1|refseq:NP_001191114.1|refseq:NP_001191115.1|refseq:NP_001191117.1|refseq:NP_001191118.1|refseq:NP_001191119.1|refseq:NP_001191120.1|refseq:NP_005418.1|refseq:NP_001191121.1|refseq:NP_001191116.1|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007049"(cell cycle)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0010243"(response to organonitrogen compound)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030054"(cell junction)|go:"GO:0042493"|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|ensembl:ENSG00000078900(gene)|ensembl:ENST00000378295(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001822"(kidney development)|go:"GO:0002039"(p53 binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006298"(mismatch repair)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0097371"(MDM2/MDM4 family protein binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR002117(p53 tumor antigen)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR010991(p53, tetramerisation)|interpro:IPR011615(p53, DNA-binding)|interpro:IPR012346(p53 and RUNT-type transcription factor, DNA-binding)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR032646|interpro:IPR036674|interpro:IPR037612|mint:O15350|rcsb pdb:1COK|rcsb pdb:1DXS|rcsb pdb:2KBY|rcsb pdb:2MPS|rcsb pdb:2NB1|rcsb pdb:2WQI|rcsb pdb:2WQJ|rcsb pdb:2WTT|rcsb pdb:2XWC|rcsb pdb:3VD0|rcsb pdb:3VD1|rcsb pdb:3VD2|rcsb pdb:4A63|rcsb pdb:4G82|rcsb pdb:4G83|rcsb pdb:4GUO|rcsb pdb:4GUQ|rcsb pdb:5HOB|rcsb pdb:5HOC|rcsb pdb:5KBD|rcsb pdb:6FGS|rcsb pdb:6IJQ|reactome:R-HSA-139915|reactome:R-HSA-6803204|reactome:R-HSA-6803205|reactome:R-HSA-6803207|reactome:R-HSA-6803211|reactome:R-HSA-6804759|reactome:R-HSA-8939236|dip:DIP-24202N	ensembl:ENST00000346387|ensembl:ENSP00000340740|ensembl:ENST00000354437|ensembl:ENSP00000346423|ensembl:ENST00000357733|ensembl:ENSP00000350366|ensembl:ENST00000378285|ensembl:ENSP00000367534|ensembl:ENST00000378288|ensembl:ENSP00000367537|ensembl:ENST00000378290|ensembl:ENSP00000367539|ensembl:ENSP00000367545|ensembl:ENST00000603362|ensembl:ENSP00000474626|ensembl:ENST00000604074|ensembl:ENSP00000475143|ensembl:ENST00000604479|ensembl:ENSP00000474322|refseq:NP_001119712.1|refseq:NP_001119713.1|refseq:NP_001119714.1|refseq:NP_001191113.1|refseq:NP_001191114.1|refseq:NP_001191115.1|refseq:NP_001191117.1|refseq:NP_001191118.1|refseq:NP_001191119.1|refseq:NP_001191120.1|refseq:NP_005418.1|refseq:NP_001191121.1|refseq:NP_001191116.1|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007049"(cell cycle)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0010243"(response to organonitrogen compound)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030054"(cell junction)|go:"GO:0042493"|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|ensembl:ENSG00000078900(gene)|ensembl:ENST00000378295(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001822"(kidney development)|go:"GO:0002039"(p53 binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006298"(mismatch repair)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0097371"(MDM2/MDM4 family protein binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR002117(p53 tumor antigen)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR010991(p53, tetramerisation)|interpro:IPR011615(p53, DNA-binding)|interpro:IPR012346(p53 and RUNT-type transcription factor, DNA-binding)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR032646|interpro:IPR036674|interpro:IPR037612|mint:O15350|rcsb pdb:1COK|rcsb pdb:1DXS|rcsb pdb:2KBY|rcsb pdb:2MPS|rcsb pdb:2NB1|rcsb pdb:2WQI|rcsb pdb:2WQJ|rcsb pdb:2WTT|rcsb pdb:2XWC|rcsb pdb:3VD0|rcsb pdb:3VD1|rcsb pdb:3VD2|rcsb pdb:4A63|rcsb pdb:4G82|rcsb pdb:4G83|rcsb pdb:4GUO|rcsb pdb:4GUQ|rcsb pdb:5HOB|rcsb pdb:5HOC|rcsb pdb:5KBD|rcsb pdb:6FGS|rcsb pdb:6IJQ|reactome:R-HSA-139915|reactome:R-HSA-6803204|reactome:R-HSA-6803205|reactome:R-HSA-6803207|reactome:R-HSA-6803211|reactome:R-HSA-6804759|reactome:R-HSA-8939236|dip:DIP-24202N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:562(ecolx)|taxid:562(Escherichia coli)	-	2017/08/06	2017/08/10	rogid:KwI8l1a8t8GHsZwMDi4v2bqwe0c9606	rogid:KwI8l1a8t8GHsZwMDi4v2bqwe0c9606	rigid:OdU5/lVUUkIb6LHyiKByXrUL5+M	false	binding-associated region:351-383	binding-associated region:351-383	-	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9H3D4	uniprotkb:Q9H3D4	intact:EBI-2337775|uniprotkb:O75080|uniprotkb:O75195|uniprotkb:O75922|uniprotkb:O76078|uniprotkb:Q6VEG2|uniprotkb:Q6VEG3|uniprotkb:Q6VEG4|uniprotkb:Q6VFJ1|uniprotkb:Q6VFJ2|uniprotkb:Q6VFJ3|uniprotkb:Q6VH20|uniprotkb:Q7LDI3|uniprotkb:Q7LDI4|uniprotkb:Q7LDI5|uniprotkb:Q96KR0|uniprotkb:Q9H3D2|uniprotkb:Q9H3D3|uniprotkb:Q9H3P8|uniprotkb:Q9NPH7|uniprotkb:Q9P1B4|uniprotkb:Q9P1B5|uniprotkb:Q9P1B6|uniprotkb:Q9P1B7|uniprotkb:Q9UBV9|uniprotkb:Q9UE10|uniprotkb:Q9UP26|uniprotkb:Q9UP27|uniprotkb:Q9UP28|uniprotkb:Q9UP74|ensembl:ENSP00000264731	intact:EBI-2337775|uniprotkb:O75080|uniprotkb:O75195|uniprotkb:O75922|uniprotkb:O76078|uniprotkb:Q6VEG2|uniprotkb:Q6VEG3|uniprotkb:Q6VEG4|uniprotkb:Q6VFJ1|uniprotkb:Q6VFJ2|uniprotkb:Q6VFJ3|uniprotkb:Q6VH20|uniprotkb:Q7LDI3|uniprotkb:Q7LDI4|uniprotkb:Q7LDI5|uniprotkb:Q96KR0|uniprotkb:Q9H3D2|uniprotkb:Q9H3D3|uniprotkb:Q9H3P8|uniprotkb:Q9NPH7|uniprotkb:Q9P1B4|uniprotkb:Q9P1B5|uniprotkb:Q9P1B6|uniprotkb:Q9P1B7|uniprotkb:Q9UBV9|uniprotkb:Q9UE10|uniprotkb:Q9UP26|uniprotkb:Q9UP27|uniprotkb:Q9UP28|uniprotkb:Q9UP74|ensembl:ENSP00000264731	psi-mi:p63_human(display_long)|uniprotkb:TP63(gene name)|psi-mi:TP63(display_short)|uniprotkb:KET(gene name synonym)|uniprotkb:P63(gene name synonym)|uniprotkb:P73H(gene name synonym)|uniprotkb:P73L(gene name synonym)|uniprotkb:TP73L(gene name synonym)|uniprotkb:Transformation-related protein 63(gene name synonym)|uniprotkb:Tumor protein p73-like(gene name synonym)|uniprotkb:p51(gene name synonym)|uniprotkb:p40(gene name synonym)|uniprotkb:Keratinocyte transcription factor KET(gene name synonym)|uniprotkb:Chronic ulcerative stomatitis protein(gene name synonym)	psi-mi:p63_human(display_long)|uniprotkb:TP63(gene name)|psi-mi:TP63(display_short)|uniprotkb:KET(gene name synonym)|uniprotkb:P63(gene name synonym)|uniprotkb:P73H(gene name synonym)|uniprotkb:P73L(gene name synonym)|uniprotkb:TP73L(gene name synonym)|uniprotkb:Transformation-related protein 63(gene name synonym)|uniprotkb:Tumor protein p73-like(gene name synonym)|uniprotkb:p51(gene name synonym)|uniprotkb:p40(gene name synonym)|uniprotkb:Keratinocyte transcription factor KET(gene name synonym)|uniprotkb:Chronic ulcerative stomatitis protein(gene name synonym)	psi-mi:"MI:0069"(mass spectrometry studies of complexes)	Joerger et al. (2009)	pubmed:19815500|doi:10.1073/pnas.0905867106|imex:IM-14849	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15808187|imex:IM-14849-3|dip:DIP-104164E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001108450.1|refseq:NP_001108451.1|refseq:NP_001108452.1|refseq:NP_001108453.1|refseq:NP_001108454.1|refseq:NP_003713.3|ensembl:ENSP00000264731|ensembl:ENST00000320472|ensembl:ENSP00000317510|ensembl:ENST00000354600|ensembl:ENSP00000346614|ensembl:ENST00000392460|ensembl:ENSP00000376253|ensembl:ENST00000392461|ensembl:ENSP00000376254|ensembl:ENST00000392463|ensembl:ENSP00000376256|ensembl:ENST00000418709|ensembl:ENSP00000407144|ensembl:ENST00000437221|ensembl:ENSP00000392488|ensembl:ENST00000440651|ensembl:ENSP00000394337|ensembl:ENST00000449992|ensembl:ENSP00000387839|ensembl:ENST00000456148|ensembl:ENSP00000389485|refseq:NP_001316073.1|refseq:NP_001316074.1|refseq:NP_001316075.1|refseq:NP_001316077.1|refseq:XP_016862876.1|dip:DIP-29588N|interpro:IPR002117(p53 tumor antigen)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR010991(p53, tetramerisation)|interpro:IPR011615(p53, DNA-binding)|interpro:IPR012346(p53 and RUNT-type transcription factor, DNA-binding)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR032645|interpro:IPR036674|interpro:IPR037611|mint:Q9H3D4|rcsb pdb:1RG6|rcsb pdb:2NB1|rcsb pdb:2RMN|rcsb pdb:2Y9T|rcsb pdb:2Y9U|rcsb pdb:3QYM|rcsb pdb:3QYN|rcsb pdb:3US0|rcsb pdb:3US1|rcsb pdb:3US2|rcsb pdb:3ZY0|rcsb pdb:3ZY1|rcsb pdb:4A9Z|rcsb pdb:6FGN|rcsb pdb:6RU6|rcsb pdb:6RU7|rcsb pdb:6RU8|reactome:R-HSA-139915|reactome:R-HSA-5620971|reactome:R-HSA-5628897|reactome:R-HSA-6803204|reactome:R-HSA-6803205|reactome:R-HSA-6803207|reactome:R-HSA-6803211|reactome:R-HSA-6804759|interpro:IPR001660(Sterile alpha motif SAM)|ensembl:ENSG00000073282(gene)|ensembl:ENST00000264731(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001501"(skeletal system development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0002039"(p53 binding)|go:"GO:0002064"(epithelial cell development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007499"(ectoderm and mesoderm interaction)|go:"GO:0007569"(cell aging)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0010259"(multicellular organism aging)|go:"GO:0010481"(epidermal cell division)|go:"GO:0010482"(regulation of epidermal cell division)|go:"GO:0010838"(positive regulation of keratinocyte proliferation)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030425"(dendrite)|go:"GO:0030859"(polarized epithelial cell differentiation)|go:"GO:0031069"(hair follicle morphogenesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043589"(skin morphogenesis)|go:"GO:0045617"(negative regulation of keratinocyte differentiation)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048485"(sympathetic nervous system development)|go:"GO:0048807"(female genitalia morphogenesis)|go:"GO:0050699"(WW domain binding)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0060197"(cloacal septation)|go:"GO:0060513"(prostatic bud formation)|go:"GO:0060529"(squamous basal epithelial stem cell differentiation involved in prostate gland acinus development)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0097371"(MDM2/MDM4 family protein binding)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|go:"GO:1904674"(positive regulation of somatic stem cell population maintenance)|go:"GO:1904888"(cranial skeletal system development)|go:"GO:2000271"(positive regulation of fibroblast apoptotic process)|go:"GO:2000381"(negative regulation of mesoderm development)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)	refseq:NP_001108450.1|refseq:NP_001108451.1|refseq:NP_001108452.1|refseq:NP_001108453.1|refseq:NP_001108454.1|refseq:NP_003713.3|ensembl:ENSP00000264731|ensembl:ENST00000320472|ensembl:ENSP00000317510|ensembl:ENST00000354600|ensembl:ENSP00000346614|ensembl:ENST00000392460|ensembl:ENSP00000376253|ensembl:ENST00000392461|ensembl:ENSP00000376254|ensembl:ENST00000392463|ensembl:ENSP00000376256|ensembl:ENST00000418709|ensembl:ENSP00000407144|ensembl:ENST00000437221|ensembl:ENSP00000392488|ensembl:ENST00000440651|ensembl:ENSP00000394337|ensembl:ENST00000449992|ensembl:ENSP00000387839|ensembl:ENST00000456148|ensembl:ENSP00000389485|refseq:NP_001316073.1|refseq:NP_001316074.1|refseq:NP_001316075.1|refseq:NP_001316077.1|refseq:XP_016862876.1|dip:DIP-29588N|interpro:IPR002117(p53 tumor antigen)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR010991(p53, tetramerisation)|interpro:IPR011615(p53, DNA-binding)|interpro:IPR012346(p53 and RUNT-type transcription factor, DNA-binding)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR032645|interpro:IPR036674|interpro:IPR037611|mint:Q9H3D4|rcsb pdb:1RG6|rcsb pdb:2NB1|rcsb pdb:2RMN|rcsb pdb:2Y9T|rcsb pdb:2Y9U|rcsb pdb:3QYM|rcsb pdb:3QYN|rcsb pdb:3US0|rcsb pdb:3US1|rcsb pdb:3US2|rcsb pdb:3ZY0|rcsb pdb:3ZY1|rcsb pdb:4A9Z|rcsb pdb:6FGN|rcsb pdb:6RU6|rcsb pdb:6RU7|rcsb pdb:6RU8|reactome:R-HSA-139915|reactome:R-HSA-5620971|reactome:R-HSA-5628897|reactome:R-HSA-6803204|reactome:R-HSA-6803205|reactome:R-HSA-6803207|reactome:R-HSA-6803211|reactome:R-HSA-6804759|interpro:IPR001660(Sterile alpha motif SAM)|ensembl:ENSG00000073282(gene)|ensembl:ENST00000264731(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001501"(skeletal system development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0002039"(p53 binding)|go:"GO:0002064"(epithelial cell development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007499"(ectoderm and mesoderm interaction)|go:"GO:0007569"(cell aging)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0010259"(multicellular organism aging)|go:"GO:0010481"(epidermal cell division)|go:"GO:0010482"(regulation of epidermal cell division)|go:"GO:0010838"(positive regulation of keratinocyte proliferation)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030425"(dendrite)|go:"GO:0030859"(polarized epithelial cell differentiation)|go:"GO:0031069"(hair follicle morphogenesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043589"(skin morphogenesis)|go:"GO:0045617"(negative regulation of keratinocyte differentiation)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048485"(sympathetic nervous system development)|go:"GO:0048807"(female genitalia morphogenesis)|go:"GO:0050699"(WW domain binding)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0060197"(cloacal septation)|go:"GO:0060513"(prostatic bud formation)|go:"GO:0060529"(squamous basal epithelial stem cell differentiation involved in prostate gland acinus development)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0097371"(MDM2/MDM4 family protein binding)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|go:"GO:1904674"(positive regulation of somatic stem cell population maintenance)|go:"GO:1904888"(cranial skeletal system development)|go:"GO:2000271"(positive regulation of fibroblast apoptotic process)|go:"GO:2000381"(negative regulation of mesoderm development)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:562(ecolx)|taxid:562(Escherichia coli)	-	2017/08/06	2017/08/10	rogid:dwFwax9/monTAo8mJp1y7aGh+Cs9606	rogid:dwFwax9/monTAo8mJp1y7aGh+Cs9606	rigid:zJg+QCgNZ33GXoTpVsoWgfCgReM	false	binding-associated region:356-411	binding-associated region:356-411	-	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O15350	uniprotkb:O15350	intact:EBI-389606|uniprotkb:O15351|uniprotkb:Q17RN8|uniprotkb:Q5TBV5|uniprotkb:Q5TBV6|uniprotkb:Q8NHW9|uniprotkb:Q8TDY5|uniprotkb:Q8TDY6|uniprotkb:Q9NTK8|uniprotkb:B7Z9C1|uniprotkb:B7Z8Z1|uniprotkb:C9J521|uniprotkb:B7Z7J4|ensembl:ENSP00000367545	intact:EBI-389606|uniprotkb:O15351|uniprotkb:Q17RN8|uniprotkb:Q5TBV5|uniprotkb:Q5TBV6|uniprotkb:Q8NHW9|uniprotkb:Q8TDY5|uniprotkb:Q8TDY6|uniprotkb:Q9NTK8|uniprotkb:B7Z9C1|uniprotkb:B7Z8Z1|uniprotkb:C9J521|uniprotkb:B7Z7J4|ensembl:ENSP00000367545	psi-mi:p73_human(display_long)|uniprotkb:TP73(gene name)|psi-mi:TP73(display_short)|uniprotkb:P73(gene name synonym)|uniprotkb:p53-like transcription factor(gene name synonym)|uniprotkb:p53-related protein(gene name synonym)	psi-mi:p73_human(display_long)|uniprotkb:TP73(gene name)|psi-mi:TP73(display_short)|uniprotkb:P73(gene name synonym)|uniprotkb:p53-like transcription factor(gene name synonym)|uniprotkb:p53-related protein(gene name synonym)	psi-mi:"MI:0028"(cosedimentation in solution)	Joerger et al. (2009)	pubmed:19815500|doi:10.1073/pnas.0905867106|imex:IM-14849	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15808205|imex:IM-14849-4|dip:DIP-104163E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000346387|ensembl:ENSP00000340740|ensembl:ENST00000354437|ensembl:ENSP00000346423|ensembl:ENST00000357733|ensembl:ENSP00000350366|ensembl:ENST00000378285|ensembl:ENSP00000367534|ensembl:ENST00000378288|ensembl:ENSP00000367537|ensembl:ENST00000378290|ensembl:ENSP00000367539|ensembl:ENSP00000367545|ensembl:ENST00000603362|ensembl:ENSP00000474626|ensembl:ENST00000604074|ensembl:ENSP00000475143|ensembl:ENST00000604479|ensembl:ENSP00000474322|refseq:NP_001119712.1|refseq:NP_001119713.1|refseq:NP_001119714.1|refseq:NP_001191113.1|refseq:NP_001191114.1|refseq:NP_001191115.1|refseq:NP_001191117.1|refseq:NP_001191118.1|refseq:NP_001191119.1|refseq:NP_001191120.1|refseq:NP_005418.1|refseq:NP_001191121.1|refseq:NP_001191116.1|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007049"(cell cycle)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0010243"(response to organonitrogen compound)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030054"(cell junction)|go:"GO:0042493"|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|ensembl:ENSG00000078900(gene)|ensembl:ENST00000378295(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001822"(kidney development)|go:"GO:0002039"(p53 binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006298"(mismatch repair)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0097371"(MDM2/MDM4 family protein binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR002117(p53 tumor antigen)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR010991(p53, tetramerisation)|interpro:IPR011615(p53, DNA-binding)|interpro:IPR012346(p53 and RUNT-type transcription factor, DNA-binding)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR032646|interpro:IPR036674|interpro:IPR037612|mint:O15350|rcsb pdb:1COK|rcsb pdb:1DXS|rcsb pdb:2KBY|rcsb pdb:2MPS|rcsb pdb:2NB1|rcsb pdb:2WQI|rcsb pdb:2WQJ|rcsb pdb:2WTT|rcsb pdb:2XWC|rcsb pdb:3VD0|rcsb pdb:3VD1|rcsb pdb:3VD2|rcsb pdb:4A63|rcsb pdb:4G82|rcsb pdb:4G83|rcsb pdb:4GUO|rcsb pdb:4GUQ|rcsb pdb:5HOB|rcsb pdb:5HOC|rcsb pdb:5KBD|rcsb pdb:6FGS|rcsb pdb:6IJQ|reactome:R-HSA-139915|reactome:R-HSA-6803204|reactome:R-HSA-6803205|reactome:R-HSA-6803207|reactome:R-HSA-6803211|reactome:R-HSA-6804759|reactome:R-HSA-8939236|dip:DIP-24202N	ensembl:ENST00000346387|ensembl:ENSP00000340740|ensembl:ENST00000354437|ensembl:ENSP00000346423|ensembl:ENST00000357733|ensembl:ENSP00000350366|ensembl:ENST00000378285|ensembl:ENSP00000367534|ensembl:ENST00000378288|ensembl:ENSP00000367537|ensembl:ENST00000378290|ensembl:ENSP00000367539|ensembl:ENSP00000367545|ensembl:ENST00000603362|ensembl:ENSP00000474626|ensembl:ENST00000604074|ensembl:ENSP00000475143|ensembl:ENST00000604479|ensembl:ENSP00000474322|refseq:NP_001119712.1|refseq:NP_001119713.1|refseq:NP_001119714.1|refseq:NP_001191113.1|refseq:NP_001191114.1|refseq:NP_001191115.1|refseq:NP_001191117.1|refseq:NP_001191118.1|refseq:NP_001191119.1|refseq:NP_001191120.1|refseq:NP_005418.1|refseq:NP_001191121.1|refseq:NP_001191116.1|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007049"(cell cycle)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0010243"(response to organonitrogen compound)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030054"(cell junction)|go:"GO:0042493"|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|ensembl:ENSG00000078900(gene)|ensembl:ENST00000378295(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001822"(kidney development)|go:"GO:0002039"(p53 binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006298"(mismatch repair)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0097371"(MDM2/MDM4 family protein binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR002117(p53 tumor antigen)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR010991(p53, tetramerisation)|interpro:IPR011615(p53, DNA-binding)|interpro:IPR012346(p53 and RUNT-type transcription factor, DNA-binding)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR032646|interpro:IPR036674|interpro:IPR037612|mint:O15350|rcsb pdb:1COK|rcsb pdb:1DXS|rcsb pdb:2KBY|rcsb pdb:2MPS|rcsb pdb:2NB1|rcsb pdb:2WQI|rcsb pdb:2WQJ|rcsb pdb:2WTT|rcsb pdb:2XWC|rcsb pdb:3VD0|rcsb pdb:3VD1|rcsb pdb:3VD2|rcsb pdb:4A63|rcsb pdb:4G82|rcsb pdb:4G83|rcsb pdb:4GUO|rcsb pdb:4GUQ|rcsb pdb:5HOB|rcsb pdb:5HOC|rcsb pdb:5KBD|rcsb pdb:6FGS|rcsb pdb:6IJQ|reactome:R-HSA-139915|reactome:R-HSA-6803204|reactome:R-HSA-6803205|reactome:R-HSA-6803207|reactome:R-HSA-6803211|reactome:R-HSA-6804759|reactome:R-HSA-8939236|dip:DIP-24202N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:562(ecolx)|taxid:562(Escherichia coli)	-	2017/08/06	2017/08/10	rogid:KwI8l1a8t8GHsZwMDi4v2bqwe0c9606	rogid:KwI8l1a8t8GHsZwMDi4v2bqwe0c9606	rigid:OdU5/lVUUkIb6LHyiKByXrUL5+M	false	binding-associated region:351-383	binding-associated region:351-383	-	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9H3D4	uniprotkb:Q9H3D4	intact:EBI-2337775|uniprotkb:O75080|uniprotkb:O75195|uniprotkb:O75922|uniprotkb:O76078|uniprotkb:Q6VEG2|uniprotkb:Q6VEG3|uniprotkb:Q6VEG4|uniprotkb:Q6VFJ1|uniprotkb:Q6VFJ2|uniprotkb:Q6VFJ3|uniprotkb:Q6VH20|uniprotkb:Q7LDI3|uniprotkb:Q7LDI4|uniprotkb:Q7LDI5|uniprotkb:Q96KR0|uniprotkb:Q9H3D2|uniprotkb:Q9H3D3|uniprotkb:Q9H3P8|uniprotkb:Q9NPH7|uniprotkb:Q9P1B4|uniprotkb:Q9P1B5|uniprotkb:Q9P1B6|uniprotkb:Q9P1B7|uniprotkb:Q9UBV9|uniprotkb:Q9UE10|uniprotkb:Q9UP26|uniprotkb:Q9UP27|uniprotkb:Q9UP28|uniprotkb:Q9UP74|ensembl:ENSP00000264731	intact:EBI-2337775|uniprotkb:O75080|uniprotkb:O75195|uniprotkb:O75922|uniprotkb:O76078|uniprotkb:Q6VEG2|uniprotkb:Q6VEG3|uniprotkb:Q6VEG4|uniprotkb:Q6VFJ1|uniprotkb:Q6VFJ2|uniprotkb:Q6VFJ3|uniprotkb:Q6VH20|uniprotkb:Q7LDI3|uniprotkb:Q7LDI4|uniprotkb:Q7LDI5|uniprotkb:Q96KR0|uniprotkb:Q9H3D2|uniprotkb:Q9H3D3|uniprotkb:Q9H3P8|uniprotkb:Q9NPH7|uniprotkb:Q9P1B4|uniprotkb:Q9P1B5|uniprotkb:Q9P1B6|uniprotkb:Q9P1B7|uniprotkb:Q9UBV9|uniprotkb:Q9UE10|uniprotkb:Q9UP26|uniprotkb:Q9UP27|uniprotkb:Q9UP28|uniprotkb:Q9UP74|ensembl:ENSP00000264731	psi-mi:p63_human(display_long)|uniprotkb:TP63(gene name)|psi-mi:TP63(display_short)|uniprotkb:KET(gene name synonym)|uniprotkb:P63(gene name synonym)|uniprotkb:P73H(gene name synonym)|uniprotkb:P73L(gene name synonym)|uniprotkb:TP73L(gene name synonym)|uniprotkb:Transformation-related protein 63(gene name synonym)|uniprotkb:Tumor protein p73-like(gene name synonym)|uniprotkb:p51(gene name synonym)|uniprotkb:p40(gene name synonym)|uniprotkb:Keratinocyte transcription factor KET(gene name synonym)|uniprotkb:Chronic ulcerative stomatitis protein(gene name synonym)	psi-mi:p63_human(display_long)|uniprotkb:TP63(gene name)|psi-mi:TP63(display_short)|uniprotkb:KET(gene name synonym)|uniprotkb:P63(gene name synonym)|uniprotkb:P73H(gene name synonym)|uniprotkb:P73L(gene name synonym)|uniprotkb:TP73L(gene name synonym)|uniprotkb:Transformation-related protein 63(gene name synonym)|uniprotkb:Tumor protein p73-like(gene name synonym)|uniprotkb:p51(gene name synonym)|uniprotkb:p40(gene name synonym)|uniprotkb:Keratinocyte transcription factor KET(gene name synonym)|uniprotkb:Chronic ulcerative stomatitis protein(gene name synonym)	psi-mi:"MI:0028"(cosedimentation in solution)	Joerger et al. (2009)	pubmed:19815500|doi:10.1073/pnas.0905867106|imex:IM-14849	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15808223|imex:IM-14849-5|dip:DIP-104164E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001108450.1|refseq:NP_001108451.1|refseq:NP_001108452.1|refseq:NP_001108453.1|refseq:NP_001108454.1|refseq:NP_003713.3|ensembl:ENSP00000264731|ensembl:ENST00000320472|ensembl:ENSP00000317510|ensembl:ENST00000354600|ensembl:ENSP00000346614|ensembl:ENST00000392460|ensembl:ENSP00000376253|ensembl:ENST00000392461|ensembl:ENSP00000376254|ensembl:ENST00000392463|ensembl:ENSP00000376256|ensembl:ENST00000418709|ensembl:ENSP00000407144|ensembl:ENST00000437221|ensembl:ENSP00000392488|ensembl:ENST00000440651|ensembl:ENSP00000394337|ensembl:ENST00000449992|ensembl:ENSP00000387839|ensembl:ENST00000456148|ensembl:ENSP00000389485|refseq:NP_001316073.1|refseq:NP_001316074.1|refseq:NP_001316075.1|refseq:NP_001316077.1|refseq:XP_016862876.1|dip:DIP-29588N|interpro:IPR002117(p53 tumor antigen)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR010991(p53, tetramerisation)|interpro:IPR011615(p53, DNA-binding)|interpro:IPR012346(p53 and RUNT-type transcription factor, DNA-binding)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR032645|interpro:IPR036674|interpro:IPR037611|mint:Q9H3D4|rcsb pdb:1RG6|rcsb pdb:2NB1|rcsb pdb:2RMN|rcsb pdb:2Y9T|rcsb pdb:2Y9U|rcsb pdb:3QYM|rcsb pdb:3QYN|rcsb pdb:3US0|rcsb pdb:3US1|rcsb pdb:3US2|rcsb pdb:3ZY0|rcsb pdb:3ZY1|rcsb pdb:4A9Z|rcsb pdb:6FGN|rcsb pdb:6RU6|rcsb pdb:6RU7|rcsb pdb:6RU8|reactome:R-HSA-139915|reactome:R-HSA-5620971|reactome:R-HSA-5628897|reactome:R-HSA-6803204|reactome:R-HSA-6803205|reactome:R-HSA-6803207|reactome:R-HSA-6803211|reactome:R-HSA-6804759|interpro:IPR001660(Sterile alpha motif SAM)|ensembl:ENSG00000073282(gene)|ensembl:ENST00000264731(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001501"(skeletal system development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0002039"(p53 binding)|go:"GO:0002064"(epithelial cell development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007499"(ectoderm and mesoderm interaction)|go:"GO:0007569"(cell aging)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0010259"(multicellular organism aging)|go:"GO:0010481"(epidermal cell division)|go:"GO:0010482"(regulation of epidermal cell division)|go:"GO:0010838"(positive regulation of keratinocyte proliferation)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030425"(dendrite)|go:"GO:0030859"(polarized epithelial cell differentiation)|go:"GO:0031069"(hair follicle morphogenesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043589"(skin morphogenesis)|go:"GO:0045617"(negative regulation of keratinocyte differentiation)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048485"(sympathetic nervous system development)|go:"GO:0048807"(female genitalia morphogenesis)|go:"GO:0050699"(WW domain binding)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0060197"(cloacal septation)|go:"GO:0060513"(prostatic bud formation)|go:"GO:0060529"(squamous basal epithelial stem cell differentiation involved in prostate gland acinus development)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0097371"(MDM2/MDM4 family protein binding)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|go:"GO:1904674"(positive regulation of somatic stem cell population maintenance)|go:"GO:1904888"(cranial skeletal system development)|go:"GO:2000271"(positive regulation of fibroblast apoptotic process)|go:"GO:2000381"(negative regulation of mesoderm development)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)	refseq:NP_001108450.1|refseq:NP_001108451.1|refseq:NP_001108452.1|refseq:NP_001108453.1|refseq:NP_001108454.1|refseq:NP_003713.3|ensembl:ENSP00000264731|ensembl:ENST00000320472|ensembl:ENSP00000317510|ensembl:ENST00000354600|ensembl:ENSP00000346614|ensembl:ENST00000392460|ensembl:ENSP00000376253|ensembl:ENST00000392461|ensembl:ENSP00000376254|ensembl:ENST00000392463|ensembl:ENSP00000376256|ensembl:ENST00000418709|ensembl:ENSP00000407144|ensembl:ENST00000437221|ensembl:ENSP00000392488|ensembl:ENST00000440651|ensembl:ENSP00000394337|ensembl:ENST00000449992|ensembl:ENSP00000387839|ensembl:ENST00000456148|ensembl:ENSP00000389485|refseq:NP_001316073.1|refseq:NP_001316074.1|refseq:NP_001316075.1|refseq:NP_001316077.1|refseq:XP_016862876.1|dip:DIP-29588N|interpro:IPR002117(p53 tumor antigen)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR010991(p53, tetramerisation)|interpro:IPR011615(p53, DNA-binding)|interpro:IPR012346(p53 and RUNT-type transcription factor, DNA-binding)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR032645|interpro:IPR036674|interpro:IPR037611|mint:Q9H3D4|rcsb pdb:1RG6|rcsb pdb:2NB1|rcsb pdb:2RMN|rcsb pdb:2Y9T|rcsb pdb:2Y9U|rcsb pdb:3QYM|rcsb pdb:3QYN|rcsb pdb:3US0|rcsb pdb:3US1|rcsb pdb:3US2|rcsb pdb:3ZY0|rcsb pdb:3ZY1|rcsb pdb:4A9Z|rcsb pdb:6FGN|rcsb pdb:6RU6|rcsb pdb:6RU7|rcsb pdb:6RU8|reactome:R-HSA-139915|reactome:R-HSA-5620971|reactome:R-HSA-5628897|reactome:R-HSA-6803204|reactome:R-HSA-6803205|reactome:R-HSA-6803207|reactome:R-HSA-6803211|reactome:R-HSA-6804759|interpro:IPR001660(Sterile alpha motif SAM)|ensembl:ENSG00000073282(gene)|ensembl:ENST00000264731(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001501"(skeletal system development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0002039"(p53 binding)|go:"GO:0002064"(epithelial cell development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007499"(ectoderm and mesoderm interaction)|go:"GO:0007569"(cell aging)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0010259"(multicellular organism aging)|go:"GO:0010481"(epidermal cell division)|go:"GO:0010482"(regulation of epidermal cell division)|go:"GO:0010838"(positive regulation of keratinocyte proliferation)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030425"(dendrite)|go:"GO:0030859"(polarized epithelial cell differentiation)|go:"GO:0031069"(hair follicle morphogenesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043589"(skin morphogenesis)|go:"GO:0045617"(negative regulation of keratinocyte differentiation)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048485"(sympathetic nervous system development)|go:"GO:0048807"(female genitalia morphogenesis)|go:"GO:0050699"(WW domain binding)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0060197"(cloacal septation)|go:"GO:0060513"(prostatic bud formation)|go:"GO:0060529"(squamous basal epithelial stem cell differentiation involved in prostate gland acinus development)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0097371"(MDM2/MDM4 family protein binding)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|go:"GO:1904674"(positive regulation of somatic stem cell population maintenance)|go:"GO:1904888"(cranial skeletal system development)|go:"GO:2000271"(positive regulation of fibroblast apoptotic process)|go:"GO:2000381"(negative regulation of mesoderm development)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:562(ecolx)|taxid:562(Escherichia coli)	-	2017/08/06	2017/08/10	rogid:dwFwax9/monTAo8mJp1y7aGh+Cs9606	rogid:dwFwax9/monTAo8mJp1y7aGh+Cs9606	rigid:zJg+QCgNZ33GXoTpVsoWgfCgReM	false	binding-associated region:359-388	binding-associated region:359-388	-	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O15350	uniprotkb:O15350	intact:EBI-389606|uniprotkb:O15351|uniprotkb:Q17RN8|uniprotkb:Q5TBV5|uniprotkb:Q5TBV6|uniprotkb:Q8NHW9|uniprotkb:Q8TDY5|uniprotkb:Q8TDY6|uniprotkb:Q9NTK8|uniprotkb:B7Z9C1|uniprotkb:B7Z8Z1|uniprotkb:C9J521|uniprotkb:B7Z7J4|ensembl:ENSP00000367545	intact:EBI-389606|uniprotkb:O15351|uniprotkb:Q17RN8|uniprotkb:Q5TBV5|uniprotkb:Q5TBV6|uniprotkb:Q8NHW9|uniprotkb:Q8TDY5|uniprotkb:Q8TDY6|uniprotkb:Q9NTK8|uniprotkb:B7Z9C1|uniprotkb:B7Z8Z1|uniprotkb:C9J521|uniprotkb:B7Z7J4|ensembl:ENSP00000367545	psi-mi:p73_human(display_long)|uniprotkb:TP73(gene name)|psi-mi:TP73(display_short)|uniprotkb:P73(gene name synonym)|uniprotkb:p53-like transcription factor(gene name synonym)|uniprotkb:p53-related protein(gene name synonym)	psi-mi:p73_human(display_long)|uniprotkb:TP73(gene name)|psi-mi:TP73(display_short)|uniprotkb:P73(gene name synonym)|uniprotkb:p53-like transcription factor(gene name synonym)|uniprotkb:p53-related protein(gene name synonym)	psi-mi:"MI:0069"(mass spectrometry studies of complexes)	Joerger et al. (2009)	pubmed:19815500|doi:10.1073/pnas.0905867106|imex:IM-14849	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15808169|imex:IM-14849-2|dip:DIP-104163E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000346387|ensembl:ENSP00000340740|ensembl:ENST00000354437|ensembl:ENSP00000346423|ensembl:ENST00000357733|ensembl:ENSP00000350366|ensembl:ENST00000378285|ensembl:ENSP00000367534|ensembl:ENST00000378288|ensembl:ENSP00000367537|ensembl:ENST00000378290|ensembl:ENSP00000367539|ensembl:ENSP00000367545|ensembl:ENST00000603362|ensembl:ENSP00000474626|ensembl:ENST00000604074|ensembl:ENSP00000475143|ensembl:ENST00000604479|ensembl:ENSP00000474322|refseq:NP_001119712.1|refseq:NP_001119713.1|refseq:NP_001119714.1|refseq:NP_001191113.1|refseq:NP_001191114.1|refseq:NP_001191115.1|refseq:NP_001191117.1|refseq:NP_001191118.1|refseq:NP_001191119.1|refseq:NP_001191120.1|refseq:NP_005418.1|refseq:NP_001191121.1|refseq:NP_001191116.1|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007049"(cell cycle)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0010243"(response to organonitrogen compound)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030054"(cell junction)|go:"GO:0042493"|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|ensembl:ENSG00000078900(gene)|ensembl:ENST00000378295(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001822"(kidney development)|go:"GO:0002039"(p53 binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006298"(mismatch repair)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0097371"(MDM2/MDM4 family protein binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR002117(p53 tumor antigen)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR010991(p53, tetramerisation)|interpro:IPR011615(p53, DNA-binding)|interpro:IPR012346(p53 and RUNT-type transcription factor, DNA-binding)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR032646|interpro:IPR036674|interpro:IPR037612|mint:O15350|rcsb pdb:1COK|rcsb pdb:1DXS|rcsb pdb:2KBY|rcsb pdb:2MPS|rcsb pdb:2NB1|rcsb pdb:2WQI|rcsb pdb:2WQJ|rcsb pdb:2WTT|rcsb pdb:2XWC|rcsb pdb:3VD0|rcsb pdb:3VD1|rcsb pdb:3VD2|rcsb pdb:4A63|rcsb pdb:4G82|rcsb pdb:4G83|rcsb pdb:4GUO|rcsb pdb:4GUQ|rcsb pdb:5HOB|rcsb pdb:5HOC|rcsb pdb:5KBD|rcsb pdb:6FGS|rcsb pdb:6IJQ|reactome:R-HSA-139915|reactome:R-HSA-6803204|reactome:R-HSA-6803205|reactome:R-HSA-6803207|reactome:R-HSA-6803211|reactome:R-HSA-6804759|reactome:R-HSA-8939236|dip:DIP-24202N	ensembl:ENST00000346387|ensembl:ENSP00000340740|ensembl:ENST00000354437|ensembl:ENSP00000346423|ensembl:ENST00000357733|ensembl:ENSP00000350366|ensembl:ENST00000378285|ensembl:ENSP00000367534|ensembl:ENST00000378288|ensembl:ENSP00000367537|ensembl:ENST00000378290|ensembl:ENSP00000367539|ensembl:ENSP00000367545|ensembl:ENST00000603362|ensembl:ENSP00000474626|ensembl:ENST00000604074|ensembl:ENSP00000475143|ensembl:ENST00000604479|ensembl:ENSP00000474322|refseq:NP_001119712.1|refseq:NP_001119713.1|refseq:NP_001119714.1|refseq:NP_001191113.1|refseq:NP_001191114.1|refseq:NP_001191115.1|refseq:NP_001191117.1|refseq:NP_001191118.1|refseq:NP_001191119.1|refseq:NP_001191120.1|refseq:NP_005418.1|refseq:NP_001191121.1|refseq:NP_001191116.1|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007049"(cell cycle)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0010243"(response to organonitrogen compound)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030054"(cell junction)|go:"GO:0042493"|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|ensembl:ENSG00000078900(gene)|ensembl:ENST00000378295(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001822"(kidney development)|go:"GO:0002039"(p53 binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006298"(mismatch repair)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0097371"(MDM2/MDM4 family protein binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR002117(p53 tumor antigen)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR010991(p53, tetramerisation)|interpro:IPR011615(p53, DNA-binding)|interpro:IPR012346(p53 and RUNT-type transcription factor, DNA-binding)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR032646|interpro:IPR036674|interpro:IPR037612|mint:O15350|rcsb pdb:1COK|rcsb pdb:1DXS|rcsb pdb:2KBY|rcsb pdb:2MPS|rcsb pdb:2NB1|rcsb pdb:2WQI|rcsb pdb:2WQJ|rcsb pdb:2WTT|rcsb pdb:2XWC|rcsb pdb:3VD0|rcsb pdb:3VD1|rcsb pdb:3VD2|rcsb pdb:4A63|rcsb pdb:4G82|rcsb pdb:4G83|rcsb pdb:4GUO|rcsb pdb:4GUQ|rcsb pdb:5HOB|rcsb pdb:5HOC|rcsb pdb:5KBD|rcsb pdb:6FGS|rcsb pdb:6IJQ|reactome:R-HSA-139915|reactome:R-HSA-6803204|reactome:R-HSA-6803205|reactome:R-HSA-6803207|reactome:R-HSA-6803211|reactome:R-HSA-6804759|reactome:R-HSA-8939236|dip:DIP-24202N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:562(ecolx)|taxid:562(Escherichia coli)	-	2017/08/06	2017/08/10	rogid:KwI8l1a8t8GHsZwMDi4v2bqwe0c9606	rogid:KwI8l1a8t8GHsZwMDi4v2bqwe0c9606	rigid:OdU5/lVUUkIb6LHyiKByXrUL5+M	false	binding-associated region:351-399	binding-associated region:351-399	-	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O15350	uniprotkb:Q9H3D4	intact:EBI-389606|uniprotkb:O15351|uniprotkb:Q17RN8|uniprotkb:Q5TBV5|uniprotkb:Q5TBV6|uniprotkb:Q8NHW9|uniprotkb:Q8TDY5|uniprotkb:Q8TDY6|uniprotkb:Q9NTK8|uniprotkb:B7Z9C1|uniprotkb:B7Z8Z1|uniprotkb:C9J521|uniprotkb:B7Z7J4|ensembl:ENSP00000367545	intact:EBI-2337775|uniprotkb:O75080|uniprotkb:O75195|uniprotkb:O75922|uniprotkb:O76078|uniprotkb:Q6VEG2|uniprotkb:Q6VEG3|uniprotkb:Q6VEG4|uniprotkb:Q6VFJ1|uniprotkb:Q6VFJ2|uniprotkb:Q6VFJ3|uniprotkb:Q6VH20|uniprotkb:Q7LDI3|uniprotkb:Q7LDI4|uniprotkb:Q7LDI5|uniprotkb:Q96KR0|uniprotkb:Q9H3D2|uniprotkb:Q9H3D3|uniprotkb:Q9H3P8|uniprotkb:Q9NPH7|uniprotkb:Q9P1B4|uniprotkb:Q9P1B5|uniprotkb:Q9P1B6|uniprotkb:Q9P1B7|uniprotkb:Q9UBV9|uniprotkb:Q9UE10|uniprotkb:Q9UP26|uniprotkb:Q9UP27|uniprotkb:Q9UP28|uniprotkb:Q9UP74|ensembl:ENSP00000264731	psi-mi:p73_human(display_long)|uniprotkb:TP73(gene name)|psi-mi:TP73(display_short)|uniprotkb:P73(gene name synonym)|uniprotkb:p53-like transcription factor(gene name synonym)|uniprotkb:p53-related protein(gene name synonym)	psi-mi:p63_human(display_long)|uniprotkb:TP63(gene name)|psi-mi:TP63(display_short)|uniprotkb:KET(gene name synonym)|uniprotkb:P63(gene name synonym)|uniprotkb:P73H(gene name synonym)|uniprotkb:P73L(gene name synonym)|uniprotkb:TP73L(gene name synonym)|uniprotkb:Transformation-related protein 63(gene name synonym)|uniprotkb:Tumor protein p73-like(gene name synonym)|uniprotkb:p51(gene name synonym)|uniprotkb:p40(gene name synonym)|uniprotkb:Keratinocyte transcription factor KET(gene name synonym)|uniprotkb:Chronic ulcerative stomatitis protein(gene name synonym)	psi-mi:"MI:0069"(mass spectrometry studies of complexes)	Joerger et al. (2009)	pubmed:19815500|doi:10.1073/pnas.0905867106|imex:IM-14849	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15808241|imex:IM-14849-6|dip:DIP-71360E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000346387|ensembl:ENSP00000340740|ensembl:ENST00000354437|ensembl:ENSP00000346423|ensembl:ENST00000357733|ensembl:ENSP00000350366|ensembl:ENST00000378285|ensembl:ENSP00000367534|ensembl:ENST00000378288|ensembl:ENSP00000367537|ensembl:ENST00000378290|ensembl:ENSP00000367539|ensembl:ENSP00000367545|ensembl:ENST00000603362|ensembl:ENSP00000474626|ensembl:ENST00000604074|ensembl:ENSP00000475143|ensembl:ENST00000604479|ensembl:ENSP00000474322|refseq:NP_001119712.1|refseq:NP_001119713.1|refseq:NP_001119714.1|refseq:NP_001191113.1|refseq:NP_001191114.1|refseq:NP_001191115.1|refseq:NP_001191117.1|refseq:NP_001191118.1|refseq:NP_001191119.1|refseq:NP_001191120.1|refseq:NP_005418.1|refseq:NP_001191121.1|refseq:NP_001191116.1|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007049"(cell cycle)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0010243"(response to organonitrogen compound)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030054"(cell junction)|go:"GO:0042493"|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|ensembl:ENSG00000078900(gene)|ensembl:ENST00000378295(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001822"(kidney development)|go:"GO:0002039"(p53 binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006298"(mismatch repair)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0097371"(MDM2/MDM4 family protein binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR002117(p53 tumor antigen)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR010991(p53, tetramerisation)|interpro:IPR011615(p53, DNA-binding)|interpro:IPR012346(p53 and RUNT-type transcription factor, DNA-binding)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR032646|interpro:IPR036674|interpro:IPR037612|mint:O15350|rcsb pdb:1COK|rcsb pdb:1DXS|rcsb pdb:2KBY|rcsb pdb:2MPS|rcsb pdb:2NB1|rcsb pdb:2WQI|rcsb pdb:2WQJ|rcsb pdb:2WTT|rcsb pdb:2XWC|rcsb pdb:3VD0|rcsb pdb:3VD1|rcsb pdb:3VD2|rcsb pdb:4A63|rcsb pdb:4G82|rcsb pdb:4G83|rcsb pdb:4GUO|rcsb pdb:4GUQ|rcsb pdb:5HOB|rcsb pdb:5HOC|rcsb pdb:5KBD|rcsb pdb:6FGS|rcsb pdb:6IJQ|reactome:R-HSA-139915|reactome:R-HSA-6803204|reactome:R-HSA-6803205|reactome:R-HSA-6803207|reactome:R-HSA-6803211|reactome:R-HSA-6804759|reactome:R-HSA-8939236|dip:DIP-24202N	refseq:NP_001108450.1|refseq:NP_001108451.1|refseq:NP_001108452.1|refseq:NP_001108453.1|refseq:NP_001108454.1|refseq:NP_003713.3|ensembl:ENSP00000264731|ensembl:ENST00000320472|ensembl:ENSP00000317510|ensembl:ENST00000354600|ensembl:ENSP00000346614|ensembl:ENST00000392460|ensembl:ENSP00000376253|ensembl:ENST00000392461|ensembl:ENSP00000376254|ensembl:ENST00000392463|ensembl:ENSP00000376256|ensembl:ENST00000418709|ensembl:ENSP00000407144|ensembl:ENST00000437221|ensembl:ENSP00000392488|ensembl:ENST00000440651|ensembl:ENSP00000394337|ensembl:ENST00000449992|ensembl:ENSP00000387839|ensembl:ENST00000456148|ensembl:ENSP00000389485|refseq:NP_001316073.1|refseq:NP_001316074.1|refseq:NP_001316075.1|refseq:NP_001316077.1|refseq:XP_016862876.1|dip:DIP-29588N|interpro:IPR002117(p53 tumor antigen)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR010991(p53, tetramerisation)|interpro:IPR011615(p53, DNA-binding)|interpro:IPR012346(p53 and RUNT-type transcription factor, DNA-binding)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR032645|interpro:IPR036674|interpro:IPR037611|mint:Q9H3D4|rcsb pdb:1RG6|rcsb pdb:2NB1|rcsb pdb:2RMN|rcsb pdb:2Y9T|rcsb pdb:2Y9U|rcsb pdb:3QYM|rcsb pdb:3QYN|rcsb pdb:3US0|rcsb pdb:3US1|rcsb pdb:3US2|rcsb pdb:3ZY0|rcsb pdb:3ZY1|rcsb pdb:4A9Z|rcsb pdb:6FGN|rcsb pdb:6RU6|rcsb pdb:6RU7|rcsb pdb:6RU8|reactome:R-HSA-139915|reactome:R-HSA-5620971|reactome:R-HSA-5628897|reactome:R-HSA-6803204|reactome:R-HSA-6803205|reactome:R-HSA-6803207|reactome:R-HSA-6803211|reactome:R-HSA-6804759|interpro:IPR001660(Sterile alpha motif SAM)|ensembl:ENSG00000073282(gene)|ensembl:ENST00000264731(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001501"(skeletal system development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0002039"(p53 binding)|go:"GO:0002064"(epithelial cell development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007499"(ectoderm and mesoderm interaction)|go:"GO:0007569"(cell aging)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0010259"(multicellular organism aging)|go:"GO:0010481"(epidermal cell division)|go:"GO:0010482"(regulation of epidermal cell division)|go:"GO:0010838"(positive regulation of keratinocyte proliferation)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030425"(dendrite)|go:"GO:0030859"(polarized epithelial cell differentiation)|go:"GO:0031069"(hair follicle morphogenesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043589"(skin morphogenesis)|go:"GO:0045617"(negative regulation of keratinocyte differentiation)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048485"(sympathetic nervous system development)|go:"GO:0048807"(female genitalia morphogenesis)|go:"GO:0050699"(WW domain binding)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0060197"(cloacal septation)|go:"GO:0060513"(prostatic bud formation)|go:"GO:0060529"(squamous basal epithelial stem cell differentiation involved in prostate gland acinus development)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0097371"(MDM2/MDM4 family protein binding)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|go:"GO:1904674"(positive regulation of somatic stem cell population maintenance)|go:"GO:1904888"(cranial skeletal system development)|go:"GO:2000271"(positive regulation of fibroblast apoptotic process)|go:"GO:2000381"(negative regulation of mesoderm development)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/06	2017/08/10	rogid:KwI8l1a8t8GHsZwMDi4v2bqwe0c9606	rogid:dwFwax9/monTAo8mJp1y7aGh+Cs9606	rigid:uIrIjjMF3+F5hNSTCRx4Dv0CiWM	false	binding-associated region:351-399	binding-associated region:356-411	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)