#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P0AE06	uniprotkb:P0AE06	intact:EBI-875601|uniprotkb:P31223|uniprotkb:Q2MBW4|ensemblbacteria:AAC73565|ensemblbacteria:BAE76242	intact:EBI-875601|uniprotkb:P31223|uniprotkb:Q2MBW4|ensemblbacteria:AAC73565|ensemblbacteria:BAE76242	psi-mi:acra_ecoli(display_long)|uniprotkb:acrA(gene name)|psi-mi:acrA(display_short)|uniprotkb:lir(gene name synonym)|uniprotkb:mtcA(gene name synonym)|uniprotkb:b0463(locus name)|uniprotkb:JW0452(locus name)|uniprotkb:AcrAB-TolC multidrug efflux pump subunit AcrA(gene name synonym)|uniprotkb:Acridine resistance protein A(gene name synonym)	psi-mi:acra_ecoli(display_long)|uniprotkb:acrA(gene name)|psi-mi:acrA(display_short)|uniprotkb:lir(gene name synonym)|uniprotkb:mtcA(gene name synonym)|uniprotkb:b0463(locus name)|uniprotkb:JW0452(locus name)|uniprotkb:AcrAB-TolC multidrug efflux pump subunit AcrA(gene name synonym)|uniprotkb:Acridine resistance protein A(gene name synonym)	psi-mi:"MI:0107"(surface plasmon resonance)	Tikhonova et al. (2009)	pubmed:19805313|doi:10.1073/pnas.0906601106|imex:IM-14827	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15807053|imex:IM-14827-1|dip:DIP-57040E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_414996.1|refseq:WP_001295324.1|dip:DIP-29039N|ensemblbacteria:AAC73565(transcript)|ensemblbacteria:b0463(gene)|ensemblbacteria:BAE76242(gene)|ensemblbacteria:BAE76242(transcript)|go:"GO:0015721"(bile acid and bile salt transport)|go:"GO:0030288"(outer membrane-bounded periplasmic space)|go:"GO:0031226"(intrinsic component of plasma membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042908"(xenobiotic transport)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0046677"(response to antibiotic)|go:"GO:1990281"(efflux pump complex)|interpro:IPR006143(Secretion protein HlyD)|interpro:IPR032317|interpro:IPR043602|rcsb pdb:2F1M|rcsb pdb:5NG5|rcsb pdb:5O66|rcsb pdb:5V5S	refseq:NP_414996.1|refseq:WP_001295324.1|dip:DIP-29039N|ensemblbacteria:AAC73565(transcript)|ensemblbacteria:b0463(gene)|ensemblbacteria:BAE76242(gene)|ensemblbacteria:BAE76242(transcript)|go:"GO:0015721"(bile acid and bile salt transport)|go:"GO:0030288"(outer membrane-bounded periplasmic space)|go:"GO:0031226"(intrinsic component of plasma membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042908"(xenobiotic transport)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0046677"(response to antibiotic)|go:"GO:1990281"(efflux pump complex)|interpro:IPR006143(Secretion protein HlyD)|interpro:IPR032317|interpro:IPR043602|rcsb pdb:2F1M|rcsb pdb:5NG5|rcsb pdb:5O66|rcsb pdb:5V5S	psi-mi:"MI:0465"(dip)	crc64:5B81DD5BC2B0A077	crc64:5B81DD5BC2B0A077	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/06	2017/08/10	rogid:SAeFuPoeyyXFuBiQN5ZAQH5f5W883333	rogid:SAeFuPoeyyXFuBiQN5ZAQH5f5W883333	rigid:1lYVyLi8Do74A0mbKCansmIS4Po	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P75830	uniprotkb:P75830	intact:EBI-551961|ensemblbacteria:AAC73965|ensemblbacteria:BAA35597	intact:EBI-551961|ensemblbacteria:AAC73965|ensemblbacteria:BAA35597	psi-mi:maca_ecoli(display_long)|uniprotkb:macA(gene name)|psi-mi:macA(display_short)|uniprotkb:b0878(locus name)|uniprotkb:ybjY(gene name synonym)|uniprotkb:JW0862(locus name)	psi-mi:maca_ecoli(display_long)|uniprotkb:macA(gene name)|psi-mi:macA(display_short)|uniprotkb:b0878(locus name)|uniprotkb:ybjY(gene name synonym)|uniprotkb:JW0862(locus name)	psi-mi:"MI:0030"(cross-linking study)	Tikhonova et al. (2009)	pubmed:19805313|doi:10.1073/pnas.0906601106|imex:IM-14827	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15807087|imex:IM-14827-3|dip:DIP-104068E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_415399.4|refseq:WP_000746442.1|dip:DIP-11460N|ensemblbacteria:AAC73965(transcript)|ensemblbacteria:b0878(gene)|ensemblbacteria:BAA35597(gene)|ensemblbacteria:BAA35597(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0015562"(efflux transmembrane transporter activity)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0046677"(response to antibiotic)|go:"GO:1990196"(MacAB-TolC complex)|go:"GO:1990281"(efflux pump complex)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR006143(Secretion protein HlyD)|interpro:IPR030190|interpro:IPR032317|rcsb pdb:3FPP|rcsb pdb:5NIK|rcsb pdb:5NIL	refseq:NP_415399.4|refseq:WP_000746442.1|dip:DIP-11460N|ensemblbacteria:AAC73965(transcript)|ensemblbacteria:b0878(gene)|ensemblbacteria:BAA35597(gene)|ensemblbacteria:BAA35597(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0015562"(efflux transmembrane transporter activity)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0046677"(response to antibiotic)|go:"GO:1990196"(MacAB-TolC complex)|go:"GO:1990281"(efflux pump complex)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR006143(Secretion protein HlyD)|interpro:IPR030190|interpro:IPR032317|rcsb pdb:3FPP|rcsb pdb:5NIK|rcsb pdb:5NIL	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/06	2017/08/10	rogid:Xj1hcSaeRW/gtgzklUnnRv/9Yvw83333	rogid:Xj1hcSaeRW/gtgzklUnnRv/9Yvw83333	rigid:YOAhxB9NB9Pl8YTzMERvLmCjAOg	false	-	-	-	0	psi-mi:"MI:0817"(molecular weight estimation by silver staining)	psi-mi:"MI:0817"(molecular weight estimation by silver staining)
uniprotkb:P0AE06	uniprotkb:P0AE06	intact:EBI-875601|uniprotkb:P31223|uniprotkb:Q2MBW4|ensemblbacteria:AAC73565|ensemblbacteria:BAE76242	intact:EBI-875601|uniprotkb:P31223|uniprotkb:Q2MBW4|ensemblbacteria:AAC73565|ensemblbacteria:BAE76242	psi-mi:acra_ecoli(display_long)|uniprotkb:acrA(gene name)|psi-mi:acrA(display_short)|uniprotkb:lir(gene name synonym)|uniprotkb:mtcA(gene name synonym)|uniprotkb:b0463(locus name)|uniprotkb:JW0452(locus name)|uniprotkb:AcrAB-TolC multidrug efflux pump subunit AcrA(gene name synonym)|uniprotkb:Acridine resistance protein A(gene name synonym)	psi-mi:acra_ecoli(display_long)|uniprotkb:acrA(gene name)|psi-mi:acrA(display_short)|uniprotkb:lir(gene name synonym)|uniprotkb:mtcA(gene name synonym)|uniprotkb:b0463(locus name)|uniprotkb:JW0452(locus name)|uniprotkb:AcrAB-TolC multidrug efflux pump subunit AcrA(gene name synonym)|uniprotkb:Acridine resistance protein A(gene name synonym)	psi-mi:"MI:0030"(cross-linking study)	Tikhonova et al. (2009)	pubmed:19805313|doi:10.1073/pnas.0906601106|imex:IM-14827	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15807103|imex:IM-14827-4|dip:DIP-57040E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_414996.1|refseq:WP_001295324.1|dip:DIP-29039N|ensemblbacteria:AAC73565(transcript)|ensemblbacteria:b0463(gene)|ensemblbacteria:BAE76242(gene)|ensemblbacteria:BAE76242(transcript)|go:"GO:0015721"(bile acid and bile salt transport)|go:"GO:0030288"(outer membrane-bounded periplasmic space)|go:"GO:0031226"(intrinsic component of plasma membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042908"(xenobiotic transport)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0046677"(response to antibiotic)|go:"GO:1990281"(efflux pump complex)|interpro:IPR006143(Secretion protein HlyD)|interpro:IPR032317|interpro:IPR043602|rcsb pdb:2F1M|rcsb pdb:5NG5|rcsb pdb:5O66|rcsb pdb:5V5S	refseq:NP_414996.1|refseq:WP_001295324.1|dip:DIP-29039N|ensemblbacteria:AAC73565(transcript)|ensemblbacteria:b0463(gene)|ensemblbacteria:BAE76242(gene)|ensemblbacteria:BAE76242(transcript)|go:"GO:0015721"(bile acid and bile salt transport)|go:"GO:0030288"(outer membrane-bounded periplasmic space)|go:"GO:0031226"(intrinsic component of plasma membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042908"(xenobiotic transport)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0046677"(response to antibiotic)|go:"GO:1990281"(efflux pump complex)|interpro:IPR006143(Secretion protein HlyD)|interpro:IPR032317|interpro:IPR043602|rcsb pdb:2F1M|rcsb pdb:5NG5|rcsb pdb:5O66|rcsb pdb:5V5S	psi-mi:"MI:0465"(dip)	crc64:5B81DD5BC2B0A077	crc64:5B81DD5BC2B0A077	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/06	2017/08/10	rogid:SAeFuPoeyyXFuBiQN5ZAQH5f5W883333	rogid:SAeFuPoeyyXFuBiQN5ZAQH5f5W883333	rigid:KiltC+lzX9A7t+9ldXTu9Mj2/F0	false	-	-	-	0	psi-mi:"MI:0817"(molecular weight estimation by silver staining)	psi-mi:"MI:0817"(molecular weight estimation by silver staining)
uniprotkb:P27303	uniprotkb:P27303	intact:EBI-1119547|uniprotkb:P77356|ensemblbacteria:AAC75732|ensemblbacteria:BAA16547	intact:EBI-1119547|uniprotkb:P77356|ensemblbacteria:AAC75732|ensemblbacteria:BAA16547	psi-mi:emra_ecoli(display_long)|uniprotkb:emrA(gene name)|psi-mi:emrA(display_short)|uniprotkb:b2685(locus name)|uniprotkb:JW2660(locus name)	psi-mi:emra_ecoli(display_long)|uniprotkb:emrA(gene name)|psi-mi:emrA(display_short)|uniprotkb:b2685(locus name)|uniprotkb:JW2660(locus name)	psi-mi:"MI:0107"(surface plasmon resonance)	Tikhonova et al. (2009)	pubmed:19805313|doi:10.1073/pnas.0906601106|imex:IM-14827	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15807119|imex:IM-14827-5|dip:DIP-104067E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_417170.1|refseq:WP_001326681.1|ensemblbacteria:AAC75732(transcript)|ensemblbacteria:b2685(gene)|ensemblbacteria:BAA16547(gene)|ensemblbacteria:BAA16547(transcript)|go:"GO:0009636"(response to toxic substance)|go:"GO:0030288"(outer membrane-bounded periplasmic space)|go:"GO:0031226"(intrinsic component of plasma membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0046677"(response to antibiotic)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR005694(Efflux pump membrane protein Emr)|interpro:IPR032317|interpro:IPR043602|go:"GO:0005887"(integral component of plasma membrane)|dip:DIP-9502N	refseq:NP_417170.1|refseq:WP_001326681.1|ensemblbacteria:AAC75732(transcript)|ensemblbacteria:b2685(gene)|ensemblbacteria:BAA16547(gene)|ensemblbacteria:BAA16547(transcript)|go:"GO:0009636"(response to toxic substance)|go:"GO:0030288"(outer membrane-bounded periplasmic space)|go:"GO:0031226"(intrinsic component of plasma membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0046677"(response to antibiotic)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR005694(Efflux pump membrane protein Emr)|interpro:IPR032317|interpro:IPR043602|go:"GO:0005887"(integral component of plasma membrane)|dip:DIP-9502N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/06	2017/08/10	rogid:NBhyYld5xsQDXEk+bFsVAxELqHU83333	rogid:NBhyYld5xsQDXEk+bFsVAxELqHU83333	rigid:6CU8absJ0zqZf+8FUCHoPQ4QhqM	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P0AE06	uniprotkb:P02930	intact:EBI-875601|uniprotkb:P31223|uniprotkb:Q2MBW4|ensemblbacteria:AAC73565|ensemblbacteria:BAE76242	intact:EBI-875614|uniprotkb:Q2M9G5|ensemblbacteria:AAC76071|ensemblbacteria:BAE77091	psi-mi:acra_ecoli(display_long)|uniprotkb:acrA(gene name)|psi-mi:acrA(display_short)|uniprotkb:lir(gene name synonym)|uniprotkb:mtcA(gene name synonym)|uniprotkb:b0463(locus name)|uniprotkb:JW0452(locus name)|uniprotkb:AcrAB-TolC multidrug efflux pump subunit AcrA(gene name synonym)|uniprotkb:Acridine resistance protein A(gene name synonym)	psi-mi:tolc_ecoli(display_long)|uniprotkb:tolC(gene name)|psi-mi:tolC(display_short)|uniprotkb:mtcB(gene name synonym)|uniprotkb:mukA(gene name synonym)|uniprotkb:refI(gene name synonym)|uniprotkb:Multidrug efflux pump subunit TolC(gene name synonym)|uniprotkb:Outer membrane factor TolC(gene name synonym)|uniprotkb:colE1-i(gene name synonym)|uniprotkb:toc(gene name synonym)|uniprotkb:weeA(gene name synonym)|uniprotkb:JW5503(locus name)|uniprotkb:b3035(locus name)	psi-mi:"MI:0107"(surface plasmon resonance)	Tikhonova et al. (2009)	pubmed:19805313|doi:10.1073/pnas.0906601106|imex:IM-14827	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15807136|imex:IM-14827-6|dip:DIP-104069E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_414996.1|refseq:WP_001295324.1|dip:DIP-29039N|ensemblbacteria:AAC73565(transcript)|ensemblbacteria:b0463(gene)|ensemblbacteria:BAE76242(gene)|ensemblbacteria:BAE76242(transcript)|go:"GO:0015721"(bile acid and bile salt transport)|go:"GO:0030288"(outer membrane-bounded periplasmic space)|go:"GO:0031226"(intrinsic component of plasma membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042908"(xenobiotic transport)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0046677"(response to antibiotic)|go:"GO:1990281"(efflux pump complex)|interpro:IPR006143(Secretion protein HlyD)|interpro:IPR032317|interpro:IPR043602|rcsb pdb:2F1M|rcsb pdb:5NG5|rcsb pdb:5O66|rcsb pdb:5V5S	refseq:NP_417507.2|refseq:WP_000735278.1|dip:DIP-11007N|ensemblbacteria:AAC76071(transcript)|ensemblbacteria:b3035(gene)|ensemblbacteria:BAE77091(gene)|ensemblbacteria:BAE77091(transcript)|go:"GO:0005216"(ion channel activity)|go:"GO:0009279"(cell outer membrane)|go:"GO:0009636"(response to toxic substance)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0015125"(bile acid transmembrane transporter activity)|go:"GO:0015288"(porin activity)|go:"GO:0015562"(efflux transmembrane transporter activity)|go:"GO:0015721"(bile acid and bile salt transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030288"(outer membrane-bounded periplasmic space)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042930"(enterobactin transport)|go:"GO:0045203"(integral component of cell outer membrane)|go:"GO:0046677"(response to antibiotic)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:1990196"(MacAB-TolC complex)|go:"GO:1990281"(efflux pump complex)|interpro:IPR003423(Outer membrane efflux protein)|interpro:IPR010130(Type I secretion outer membrane protein, TolC)|rcsb pdb:1EK9|rcsb pdb:1TQQ|rcsb pdb:2VDD|rcsb pdb:2VDE|rcsb pdb:2WMZ|rcsb pdb:2XMN|rcsb pdb:5NG5|rcsb pdb:5NIK|rcsb pdb:5NIL|rcsb pdb:5O66|rcsb pdb:5V5S|rcsb pdb:6WXH|rcsb pdb:6WXI	psi-mi:"MI:0465"(dip)	crc64:5B81DD5BC2B0A077	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/06	2017/08/10	rogid:SAeFuPoeyyXFuBiQN5ZAQH5f5W883333	rogid:67LQDsYiAt6tDwigzlhM3Pp5+JA83333	rigid:2rDXo6oI3/mEDZ0gCWyje8bDnb8	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P75830	uniprotkb:P02930	intact:EBI-551961|ensemblbacteria:AAC73965|ensemblbacteria:BAA35597	intact:EBI-875614|uniprotkb:Q2M9G5|ensemblbacteria:AAC76071|ensemblbacteria:BAE77091	psi-mi:maca_ecoli(display_long)|uniprotkb:macA(gene name)|psi-mi:macA(display_short)|uniprotkb:b0878(locus name)|uniprotkb:ybjY(gene name synonym)|uniprotkb:JW0862(locus name)	psi-mi:tolc_ecoli(display_long)|uniprotkb:tolC(gene name)|psi-mi:tolC(display_short)|uniprotkb:mtcB(gene name synonym)|uniprotkb:mukA(gene name synonym)|uniprotkb:refI(gene name synonym)|uniprotkb:Multidrug efflux pump subunit TolC(gene name synonym)|uniprotkb:Outer membrane factor TolC(gene name synonym)|uniprotkb:colE1-i(gene name synonym)|uniprotkb:toc(gene name synonym)|uniprotkb:weeA(gene name synonym)|uniprotkb:JW5503(locus name)|uniprotkb:b3035(locus name)	psi-mi:"MI:0107"(surface plasmon resonance)	Tikhonova et al. (2009)	pubmed:19805313|doi:10.1073/pnas.0906601106|imex:IM-14827	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15807153|imex:IM-14827-7|dip:DIP-104070E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_415399.4|refseq:WP_000746442.1|dip:DIP-11460N|ensemblbacteria:AAC73965(transcript)|ensemblbacteria:b0878(gene)|ensemblbacteria:BAA35597(gene)|ensemblbacteria:BAA35597(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0015562"(efflux transmembrane transporter activity)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0046677"(response to antibiotic)|go:"GO:1990196"(MacAB-TolC complex)|go:"GO:1990281"(efflux pump complex)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR006143(Secretion protein HlyD)|interpro:IPR030190|interpro:IPR032317|rcsb pdb:3FPP|rcsb pdb:5NIK|rcsb pdb:5NIL	refseq:NP_417507.2|refseq:WP_000735278.1|dip:DIP-11007N|ensemblbacteria:AAC76071(transcript)|ensemblbacteria:b3035(gene)|ensemblbacteria:BAE77091(gene)|ensemblbacteria:BAE77091(transcript)|go:"GO:0005216"(ion channel activity)|go:"GO:0009279"(cell outer membrane)|go:"GO:0009636"(response to toxic substance)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0015125"(bile acid transmembrane transporter activity)|go:"GO:0015288"(porin activity)|go:"GO:0015562"(efflux transmembrane transporter activity)|go:"GO:0015721"(bile acid and bile salt transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030288"(outer membrane-bounded periplasmic space)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042930"(enterobactin transport)|go:"GO:0045203"(integral component of cell outer membrane)|go:"GO:0046677"(response to antibiotic)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:1990196"(MacAB-TolC complex)|go:"GO:1990281"(efflux pump complex)|interpro:IPR003423(Outer membrane efflux protein)|interpro:IPR010130(Type I secretion outer membrane protein, TolC)|rcsb pdb:1EK9|rcsb pdb:1TQQ|rcsb pdb:2VDD|rcsb pdb:2VDE|rcsb pdb:2WMZ|rcsb pdb:2XMN|rcsb pdb:5NG5|rcsb pdb:5NIK|rcsb pdb:5NIL|rcsb pdb:5O66|rcsb pdb:5V5S|rcsb pdb:6WXH|rcsb pdb:6WXI	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/06	2017/08/10	rogid:Xj1hcSaeRW/gtgzklUnnRv/9Yvw83333	rogid:67LQDsYiAt6tDwigzlhM3Pp5+JA83333	rigid:3ZrC3L2+BS1ofYgY9PXx0IoICUk	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P75830	uniprotkb:P75830	intact:EBI-551961|ensemblbacteria:AAC73965|ensemblbacteria:BAA35597	intact:EBI-551961|ensemblbacteria:AAC73965|ensemblbacteria:BAA35597	psi-mi:maca_ecoli(display_long)|uniprotkb:macA(gene name)|psi-mi:macA(display_short)|uniprotkb:b0878(locus name)|uniprotkb:ybjY(gene name synonym)|uniprotkb:JW0862(locus name)	psi-mi:maca_ecoli(display_long)|uniprotkb:macA(gene name)|psi-mi:macA(display_short)|uniprotkb:b0878(locus name)|uniprotkb:ybjY(gene name synonym)|uniprotkb:JW0862(locus name)	psi-mi:"MI:0107"(surface plasmon resonance)	Tikhonova et al. (2009)	pubmed:19805313|doi:10.1073/pnas.0906601106|imex:IM-14827	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15807170|imex:IM-14827-8|dip:DIP-104068E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_415399.4|refseq:WP_000746442.1|dip:DIP-11460N|ensemblbacteria:AAC73965(transcript)|ensemblbacteria:b0878(gene)|ensemblbacteria:BAA35597(gene)|ensemblbacteria:BAA35597(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0015562"(efflux transmembrane transporter activity)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0046677"(response to antibiotic)|go:"GO:1990196"(MacAB-TolC complex)|go:"GO:1990281"(efflux pump complex)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR006143(Secretion protein HlyD)|interpro:IPR030190|interpro:IPR032317|rcsb pdb:3FPP|rcsb pdb:5NIK|rcsb pdb:5NIL	refseq:NP_415399.4|refseq:WP_000746442.1|dip:DIP-11460N|ensemblbacteria:AAC73965(transcript)|ensemblbacteria:b0878(gene)|ensemblbacteria:BAA35597(gene)|ensemblbacteria:BAA35597(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0015562"(efflux transmembrane transporter activity)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0046677"(response to antibiotic)|go:"GO:1990196"(MacAB-TolC complex)|go:"GO:1990281"(efflux pump complex)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR006143(Secretion protein HlyD)|interpro:IPR030190|interpro:IPR032317|rcsb pdb:3FPP|rcsb pdb:5NIK|rcsb pdb:5NIL	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/06	2017/08/10	rogid:Xj1hcSaeRW/gtgzklUnnRv/9Yvw83333	rogid:Xj1hcSaeRW/gtgzklUnnRv/9Yvw83333	rigid:W2WQ2oZPjKG/zyeGd3k10kzWKzg	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P02930	uniprotkb:P27303	intact:EBI-875614|uniprotkb:Q2M9G5|ensemblbacteria:AAC76071|ensemblbacteria:BAE77091	intact:EBI-1119547|uniprotkb:P77356|ensemblbacteria:AAC75732|ensemblbacteria:BAA16547	psi-mi:tolc_ecoli(display_long)|uniprotkb:tolC(gene name)|psi-mi:tolC(display_short)|uniprotkb:mtcB(gene name synonym)|uniprotkb:mukA(gene name synonym)|uniprotkb:refI(gene name synonym)|uniprotkb:Multidrug efflux pump subunit TolC(gene name synonym)|uniprotkb:Outer membrane factor TolC(gene name synonym)|uniprotkb:colE1-i(gene name synonym)|uniprotkb:toc(gene name synonym)|uniprotkb:weeA(gene name synonym)|uniprotkb:JW5503(locus name)|uniprotkb:b3035(locus name)	psi-mi:emra_ecoli(display_long)|uniprotkb:emrA(gene name)|psi-mi:emrA(display_short)|uniprotkb:b2685(locus name)|uniprotkb:JW2660(locus name)	psi-mi:"MI:0107"(surface plasmon resonance)	Tikhonova et al. (2009)	pubmed:19805313|doi:10.1073/pnas.0906601106|imex:IM-14827	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15807070|imex:IM-14827-2|dip:DIP-104066E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_417507.2|refseq:WP_000735278.1|dip:DIP-11007N|ensemblbacteria:AAC76071(transcript)|ensemblbacteria:b3035(gene)|ensemblbacteria:BAE77091(gene)|ensemblbacteria:BAE77091(transcript)|go:"GO:0005216"(ion channel activity)|go:"GO:0009279"(cell outer membrane)|go:"GO:0009636"(response to toxic substance)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0015125"(bile acid transmembrane transporter activity)|go:"GO:0015288"(porin activity)|go:"GO:0015562"(efflux transmembrane transporter activity)|go:"GO:0015721"(bile acid and bile salt transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030288"(outer membrane-bounded periplasmic space)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042930"(enterobactin transport)|go:"GO:0045203"(integral component of cell outer membrane)|go:"GO:0046677"(response to antibiotic)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:1990196"(MacAB-TolC complex)|go:"GO:1990281"(efflux pump complex)|interpro:IPR003423(Outer membrane efflux protein)|interpro:IPR010130(Type I secretion outer membrane protein, TolC)|rcsb pdb:1EK9|rcsb pdb:1TQQ|rcsb pdb:2VDD|rcsb pdb:2VDE|rcsb pdb:2WMZ|rcsb pdb:2XMN|rcsb pdb:5NG5|rcsb pdb:5NIK|rcsb pdb:5NIL|rcsb pdb:5O66|rcsb pdb:5V5S|rcsb pdb:6WXH|rcsb pdb:6WXI	refseq:NP_417170.1|refseq:WP_001326681.1|ensemblbacteria:AAC75732(transcript)|ensemblbacteria:b2685(gene)|ensemblbacteria:BAA16547(gene)|ensemblbacteria:BAA16547(transcript)|go:"GO:0009636"(response to toxic substance)|go:"GO:0030288"(outer membrane-bounded periplasmic space)|go:"GO:0031226"(intrinsic component of plasma membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0046677"(response to antibiotic)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR005694(Efflux pump membrane protein Emr)|interpro:IPR032317|interpro:IPR043602|go:"GO:0005887"(integral component of plasma membrane)|dip:DIP-9502N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/06	2017/08/10	rogid:67LQDsYiAt6tDwigzlhM3Pp5+JA83333	rogid:NBhyYld5xsQDXEk+bFsVAxELqHU83333	rigid:XilhdUbGFFSlKi7kPxd53QKwJQg	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P27303	uniprotkb:P27303	intact:EBI-1119547|uniprotkb:P77356|ensemblbacteria:AAC75732|ensemblbacteria:BAA16547	intact:EBI-1119547|uniprotkb:P77356|ensemblbacteria:AAC75732|ensemblbacteria:BAA16547	psi-mi:emra_ecoli(display_long)|uniprotkb:emrA(gene name)|psi-mi:emrA(display_short)|uniprotkb:b2685(locus name)|uniprotkb:JW2660(locus name)	psi-mi:emra_ecoli(display_long)|uniprotkb:emrA(gene name)|psi-mi:emrA(display_short)|uniprotkb:b2685(locus name)|uniprotkb:JW2660(locus name)	psi-mi:"MI:0030"(cross-linking study)	Tikhonova et al. (2009)	pubmed:19805313|doi:10.1073/pnas.0906601106|imex:IM-14827	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15807187|imex:IM-14827-9|dip:DIP-104067E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_417170.1|refseq:WP_001326681.1|ensemblbacteria:AAC75732(transcript)|ensemblbacteria:b2685(gene)|ensemblbacteria:BAA16547(gene)|ensemblbacteria:BAA16547(transcript)|go:"GO:0009636"(response to toxic substance)|go:"GO:0030288"(outer membrane-bounded periplasmic space)|go:"GO:0031226"(intrinsic component of plasma membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0046677"(response to antibiotic)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR005694(Efflux pump membrane protein Emr)|interpro:IPR032317|interpro:IPR043602|go:"GO:0005887"(integral component of plasma membrane)|dip:DIP-9502N	refseq:NP_417170.1|refseq:WP_001326681.1|ensemblbacteria:AAC75732(transcript)|ensemblbacteria:b2685(gene)|ensemblbacteria:BAA16547(gene)|ensemblbacteria:BAA16547(transcript)|go:"GO:0009636"(response to toxic substance)|go:"GO:0030288"(outer membrane-bounded periplasmic space)|go:"GO:0031226"(intrinsic component of plasma membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0046677"(response to antibiotic)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR005694(Efflux pump membrane protein Emr)|interpro:IPR032317|interpro:IPR043602|go:"GO:0005887"(integral component of plasma membrane)|dip:DIP-9502N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/06	2017/08/10	rogid:NBhyYld5xsQDXEk+bFsVAxELqHU83333	rogid:NBhyYld5xsQDXEk+bFsVAxELqHU83333	rigid:q/4kBjMgVPdjlRzGg4U77Ol4yGk	false	-	-	-	0	psi-mi:"MI:0817"(molecular weight estimation by silver staining)	psi-mi:"MI:0817"(molecular weight estimation by silver staining)