#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q95SP2 uniprotkb:P06002 intact:EBI-116604|uniprotkb:Q9V9T8|ensemblmetazoa:FBpp0303146|ensemblmetazoa:FBpp0085201 intact:EBI-100064|uniprotkb:Q9TX56|ensemblmetazoa:FBpp0083266|uniprotkb:Q9VDS8|uniprotkb:A0AVV9|uniprotkb:Q4QPQ2 psi-mi:hrd1_drome(display_long)|uniprotkb:sip3(gene name)|psi-mi:sip3(display_short)|uniprotkb:CG1937(orf name)|uniprotkb:Syno(gene name synonym)|uniprotkb:Synoviolin(gene name synonym)|uniprotkb:Septin-interacting protein 3(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase HRD1(gene name synonym) psi-mi:ops1_drome(display_long)|uniprotkb:ninaE(gene name)|psi-mi:ninaE(display_short)|uniprotkb:Rh1(gene name synonym)|uniprotkb:CG4550(orf name)|uniprotkb:Outer R1-R6 photoreceptor cells opsin(gene name synonym)|uniprotkb:Neither inactivation nor afterpotential E protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kang et al. (2009) pubmed:19805114|doi:10.1073/pnas.0905566106|imex:IM-14838 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15805182|imex:IM-14838-1|dip:DIP-104128E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_651894.3|flybase:FBgn0039875|ensemblmetazoa:FBtr0085842(transcript)|ensemblmetazoa:FBtr0330113(transcript)|go:"GO:0000836"(Hrd1p ubiquitin ligase complex)|go:"GO:0002039"(p53 binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0036335"(intestinal stem cell homeostasis)|go:"GO:0036490"(regulation of translation in response to endoplasmic reticulum stress)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR032832|reactome:R-DME-5358346|ensemblmetazoa:FBgn0039875(gene)|refseq:NP_001263152.1 refseq:NP_524407.1|flybase:FBgn0002940|ensemblmetazoa:FBgn0002940(gene)|ensemblmetazoa:FBtr0083857(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005769"(early endosome)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007601"(visual perception)|go:"GO:0007602"(phototransduction)|go:"GO:0008020"(G protein-coupled photoreceptor activity)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0008594"(photoreceptor cell morphogenesis)|go:"GO:0009584"(detection of visible light)|go:"GO:0009589"(detection of UV)|go:"GO:0009642"(response to light intensity)|go:"GO:0016027"(inaD signaling complex)|go:"GO:0016028"(rhabdomere)|go:"GO:0016029"(subrhabdomeral cisterna)|go:"GO:0018298"(protein-chromophore linkage)|go:"GO:0030265"(phospholipase C-activating rhodopsin mediated signaling pathway)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0042052"(rhabdomere development)|go:"GO:0042331"(phototaxis)|go:"GO:0043052"(thermotaxis)|go:"GO:0046673"(negative regulation of compound eye retinal cell programmed cell death)|go:"GO:0071482"(cellular response to light stimulus)|go:"GO:0071632"(optomotor response)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001735(Opsin RH1/RH2)|interpro:IPR001760(Opsin)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|interpro:IPR027430|mint:P06002|dip:DIP-17500N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/06 2017/08/10 rogid:6loL3X76VDus/yDgYDP5Kl/U3N47227 rogid:HJLSoXvFeTRzj6pgJKay21a6l3U7227 rigid:it9QZH+CLnP1gwDvJsEDzdrBPwQ false myc tag:n-n ha tag:c-c - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P06002 uniprotkb:Q9VK27 intact:EBI-100064|uniprotkb:Q9TX56|ensemblmetazoa:FBpp0083266|uniprotkb:Q9VDS8|uniprotkb:A0AVV9|uniprotkb:Q4QPQ2 intact:EBI-15805203|ensemblmetazoa:FBpp0080019 psi-mi:ops1_drome(display_long)|uniprotkb:ninaE(gene name)|psi-mi:ninaE(display_short)|uniprotkb:Rh1(gene name synonym)|uniprotkb:CG4550(orf name)|uniprotkb:Outer R1-R6 photoreceptor cells opsin(gene name synonym)|uniprotkb:Neither inactivation nor afterpotential E protein(gene name synonym) psi-mi:q9vk27_drome(display_long)|uniprotkb:dEDEM2(gene name synonym)|uniprotkb:Edem2(gene name)|psi-mi:Edem2(display_short)|uniprotkb:Edem2-RA(gene name synonym)|uniprotkb:CG5682(orf name)|uniprotkb:Dmel\CG5682(gene name synonym)|uniprotkb:EDEM2(gene name synonym)|uniprotkb:edem2(gene name synonym)|uniprotkb:Dmel_CG5682(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kang et al. (2009) pubmed:19805114|doi:10.1073/pnas.0905566106|imex:IM-14838 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15805226|imex:IM-14838-2|dip:DIP-104129E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524407.1|flybase:FBgn0002940|ensemblmetazoa:FBgn0002940(gene)|ensemblmetazoa:FBtr0083857(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005769"(early endosome)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007601"(visual perception)|go:"GO:0007602"(phototransduction)|go:"GO:0008020"(G protein-coupled photoreceptor activity)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0008594"(photoreceptor cell morphogenesis)|go:"GO:0009584"(detection of visible light)|go:"GO:0009589"(detection of UV)|go:"GO:0009642"(response to light intensity)|go:"GO:0016027"(inaD signaling complex)|go:"GO:0016028"(rhabdomere)|go:"GO:0016029"(subrhabdomeral cisterna)|go:"GO:0018298"(protein-chromophore linkage)|go:"GO:0030265"(phospholipase C-activating rhodopsin mediated signaling pathway)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0042052"(rhabdomere development)|go:"GO:0042331"(phototaxis)|go:"GO:0043052"(thermotaxis)|go:"GO:0046673"(negative regulation of compound eye retinal cell programmed cell death)|go:"GO:0071482"(cellular response to light stimulus)|go:"GO:0071632"(optomotor response)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001735(Opsin RH1/RH2)|interpro:IPR001760(Opsin)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|interpro:IPR027430|mint:P06002|dip:DIP-17500N ensemblmetazoa:FBgn0032480(gene)|ensemblmetazoa:FBtr0080438(transcript)|go:"GO:0004571"(mannosyl-oligosaccharide 1,2-alpha-mannosidase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0097466"(ubiquitin-dependent glycoprotein ERAD pathway)|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|go:"GO:1904382"(mannose trimming involved in glycoprotein ERAD pathway)|interpro:IPR001382(Glycoside hydrolase, family 47)|interpro:IPR003137(Protease-associated PA)|interpro:IPR012341(Six-hairpin glycosidase)|interpro:IPR036026|interpro:IPR037322|interpro:IPR044674|refseq:NP_609611.1|flybase:FBgn0032480|dip:DIP-48981N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2017/08/06 2017/08/10 rogid:HJLSoXvFeTRzj6pgJKay21a6l3U7227 rogid:e0MC4pOjoLR3eIS/A7sokqFhJEY7227 rigid:gHR0yNIMMWjDJYdKtvr+E/i/64E false ha tag:c-c myc tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot)