#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P16371 uniprotkb:P10734 intact:EBI-153866|intact:EBI-1639108|uniprotkb:Q0KI08|uniprotkb:Q7KRZ4|uniprotkb:Q9V3F7|uniprotkb:A4V3F6|ensemblmetazoa:FBpp0089115 intact:EBI-170297|intact:EBI-1630197|uniprotkb:Q540X6|uniprotkb:Q9VPC6|ensemblmetazoa:FBpp0077941 psi-mi:grou_drome(display_long)|uniprotkb:gro(gene name)|psi-mi:gro(display_short)|uniprotkb:"E(spl)m9/m10"(gene name synonym)|uniprotkb:CG8384(orf name)|uniprotkb:Enhancer of split m9/10 protein(gene name synonym) psi-mi:knir_drome(display_long)|uniprotkb:kni(gene name)|psi-mi:kni(display_short)|uniprotkb:NR0A1(gene name synonym)|uniprotkb:CG4717(orf name)|uniprotkb:Nuclear receptor subfamily 0 group A member 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Payankaulam et al. (2009) pubmed:19805071|doi:10.1073/pnas.0904507106|imex:IM-14845 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15804825|imex:IM-14845-1|dip:DIP-104159E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001189293.1|refseq:NP_524514.2|refseq:NP_733133.1|refseq:NP_733134.1|refseq:NP_733135.1|refseq:NP_996298.1|flybase:FBgn0001139|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071837"(HMG box domain binding)|go:"GO:0071906"(CRD domain binding)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR005617(Groucho/TLE, N-terminal Q-rich region)|interpro:IPR009146(Groucho/transducin-like enhancer)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|mint:P16371|reactome:R-DME-201722|reactome:R-DME-209421|reactome:R-DME-209441|reactome:R-DME-3769402|reactome:R-DME-4641265|go:"GO:0045751"(negative regulation of Toll signaling pathway)|ensemblmetazoa:FBgn0001139(gene)|ensemblmetazoa:FBtr0084966(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007399"(nervous system development)|go:"GO:0007541"("sex determination, primary response to X:A ratio")|go:"GO:0008134"(transcription factor binding)|go:"GO:0008293"(torso signaling pathway)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030154"(cell differentiation)|go:"GO:0032991"(protein-containing complex)|dip:DIP-40N refseq:NP_524187.1|flybase:FBgn0001320|ensemblmetazoa:FBgn0001320(gene)|go:"GO:0035290"(trunk segmentation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|ensemblmetazoa:FBtr0078283(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0007354"(zygotic determination of anterior/posterior axis, embryo)|go:"GO:0007427"(epithelial cell migration, open tracheal system)|go:"GO:0008270"(zinc ion binding)|dip:DIP-17716N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2017/08/06 2017/08/10 rogid:oSo29NrCWIeCi2OMusohCk64uiw7227 rogid:zPloouLNEALRKuLvtZc0jT4RZu07227 rigid:GULCyZPZE1EhAbW+dP0E1YGtm5I false - flag tag:c-c - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P10734 uniprotkb:O46036 intact:EBI-170297|intact:EBI-1630197|uniprotkb:Q540X6|uniprotkb:Q9VPC6|ensemblmetazoa:FBpp0077941 intact:EBI-159330|uniprotkb:O61283|uniprotkb:Q59DX5|ensemblmetazoa:FBpp0099514|uniprotkb:Q95SQ8|uniprotkb:Q9VG02 psi-mi:knir_drome(display_long)|uniprotkb:kni(gene name)|psi-mi:kni(display_short)|uniprotkb:NR0A1(gene name synonym)|uniprotkb:CG4717(orf name)|uniprotkb:Nuclear receptor subfamily 0 group A member 1(gene name synonym) psi-mi:ctbp_drome(display_long)|uniprotkb:CtBP(gene name)|psi-mi:CtBP(display_short)|uniprotkb:CG7583(orf name)|uniprotkb:dCtBP(gene name synonym) psi-mi:"MI:0096"(pull down) Payankaulam et al. (2009) pubmed:19805071|doi:10.1073/pnas.0904507106|imex:IM-14845 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15804863|imex:IM-14845-3|dip:DIP-104160E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524187.1|flybase:FBgn0001320|ensemblmetazoa:FBgn0001320(gene)|go:"GO:0035290"(trunk segmentation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|ensemblmetazoa:FBtr0078283(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0007354"(zygotic determination of anterior/posterior axis, embryo)|go:"GO:0007427"(epithelial cell migration, open tracheal system)|go:"GO:0008270"(zinc ion binding)|dip:DIP-17716N refseq:NP_001014617.1|refseq:NP_524336.2|refseq:NP_731762.1|refseq:NP_731763.1|refseq:NP_731764.1|flybase:FBgn0020496|go:"GO:0016360"(sensory organ precursor cell fate determination)|go:"GO:0016616"(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|go:"GO:0022416"(chaeta development)|go:"GO:0031010"(ISWI-type complex)|go:"GO:0035220"(wing disc development)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043044"|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051287"(NAD binding)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR006139(D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region)|interpro:IPR006140(D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding)|interpro:IPR029753|interpro:IPR036291|interpro:IPR043322|mint:O46036|reactome:R-DME-3769402|go:"GO:0008134"(transcription factor binding)|ensemblmetazoa:FBgn0020496(gene)|ensemblmetazoa:FBtr0100161(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|reactome:R-DME-3899300|reactome:R-DME-4641265|refseq:NP_001262520.1|dip:DIP-17268N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2017/08/06 2017/08/10 rogid:zPloouLNEALRKuLvtZc0jT4RZu07227 rogid:hbMeldNlirFwVr+5QX9bGiPqZ1w7227 rigid:3BeDGZoicIjE7SCs8wDSi16so/0 false his tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P10734 uniprotkb:P16371 intact:EBI-170297|intact:EBI-1630197|uniprotkb:Q540X6|uniprotkb:Q9VPC6|ensemblmetazoa:FBpp0077941 intact:EBI-153866|intact:EBI-1639108|uniprotkb:Q0KI08|uniprotkb:Q7KRZ4|uniprotkb:Q9V3F7|uniprotkb:A4V3F6|ensemblmetazoa:FBpp0089115 psi-mi:knir_drome(display_long)|uniprotkb:kni(gene name)|psi-mi:kni(display_short)|uniprotkb:NR0A1(gene name synonym)|uniprotkb:CG4717(orf name)|uniprotkb:Nuclear receptor subfamily 0 group A member 1(gene name synonym) psi-mi:grou_drome(display_long)|uniprotkb:gro(gene name)|psi-mi:gro(display_short)|uniprotkb:"E(spl)m9/m10"(gene name synonym)|uniprotkb:CG8384(orf name)|uniprotkb:Enhancer of split m9/10 protein(gene name synonym) psi-mi:"MI:0096"(pull down) Payankaulam et al. (2009) pubmed:19805071|doi:10.1073/pnas.0904507106|imex:IM-14845 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15804863|imex:IM-14845-3|dip:DIP-104160E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524187.1|flybase:FBgn0001320|ensemblmetazoa:FBgn0001320(gene)|go:"GO:0035290"(trunk segmentation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|ensemblmetazoa:FBtr0078283(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0007354"(zygotic determination of anterior/posterior axis, embryo)|go:"GO:0007427"(epithelial cell migration, open tracheal system)|go:"GO:0008270"(zinc ion binding)|dip:DIP-17716N refseq:NP_001189293.1|refseq:NP_524514.2|refseq:NP_733133.1|refseq:NP_733134.1|refseq:NP_733135.1|refseq:NP_996298.1|flybase:FBgn0001139|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071837"(HMG box domain binding)|go:"GO:0071906"(CRD domain binding)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR005617(Groucho/TLE, N-terminal Q-rich region)|interpro:IPR009146(Groucho/transducin-like enhancer)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|mint:P16371|reactome:R-DME-201722|reactome:R-DME-209421|reactome:R-DME-209441|reactome:R-DME-3769402|reactome:R-DME-4641265|go:"GO:0045751"(negative regulation of Toll signaling pathway)|ensemblmetazoa:FBgn0001139(gene)|ensemblmetazoa:FBtr0084966(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007399"(nervous system development)|go:"GO:0007541"("sex determination, primary response to X:A ratio")|go:"GO:0008134"(transcription factor binding)|go:"GO:0008293"(torso signaling pathway)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030154"(cell differentiation)|go:"GO:0032991"(protein-containing complex)|dip:DIP-40N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2017/08/06 2017/08/10 rogid:zPloouLNEALRKuLvtZc0jT4RZu07227 rogid:oSo29NrCWIeCi2OMusohCk64uiw7227 rigid:3BeDGZoicIjE7SCs8wDSi16so/0 false his tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P16371 uniprotkb:P10734 intact:EBI-153866|intact:EBI-1639108|uniprotkb:Q0KI08|uniprotkb:Q7KRZ4|uniprotkb:Q9V3F7|uniprotkb:A4V3F6|ensemblmetazoa:FBpp0089115 intact:EBI-170297|intact:EBI-1630197|uniprotkb:Q540X6|uniprotkb:Q9VPC6|ensemblmetazoa:FBpp0077941 psi-mi:grou_drome(display_long)|uniprotkb:gro(gene name)|psi-mi:gro(display_short)|uniprotkb:"E(spl)m9/m10"(gene name synonym)|uniprotkb:CG8384(orf name)|uniprotkb:Enhancer of split m9/10 protein(gene name synonym) psi-mi:knir_drome(display_long)|uniprotkb:kni(gene name)|psi-mi:kni(display_short)|uniprotkb:NR0A1(gene name synonym)|uniprotkb:CG4717(orf name)|uniprotkb:Nuclear receptor subfamily 0 group A member 1(gene name synonym) psi-mi:"MI:0096"(pull down) Payankaulam et al. (2009) pubmed:19805071|doi:10.1073/pnas.0904507106|imex:IM-14845 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15804844|imex:IM-14845-2|dip:DIP-104159E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001189293.1|refseq:NP_524514.2|refseq:NP_733133.1|refseq:NP_733134.1|refseq:NP_733135.1|refseq:NP_996298.1|flybase:FBgn0001139|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071837"(HMG box domain binding)|go:"GO:0071906"(CRD domain binding)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR005617(Groucho/TLE, N-terminal Q-rich region)|interpro:IPR009146(Groucho/transducin-like enhancer)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|mint:P16371|reactome:R-DME-201722|reactome:R-DME-209421|reactome:R-DME-209441|reactome:R-DME-3769402|reactome:R-DME-4641265|go:"GO:0045751"(negative regulation of Toll signaling pathway)|ensemblmetazoa:FBgn0001139(gene)|ensemblmetazoa:FBtr0084966(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007399"(nervous system development)|go:"GO:0007541"("sex determination, primary response to X:A ratio")|go:"GO:0008134"(transcription factor binding)|go:"GO:0008293"(torso signaling pathway)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030154"(cell differentiation)|go:"GO:0032991"(protein-containing complex)|dip:DIP-40N refseq:NP_524187.1|flybase:FBgn0001320|ensemblmetazoa:FBgn0001320(gene)|go:"GO:0035290"(trunk segmentation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|ensemblmetazoa:FBtr0078283(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0007354"(zygotic determination of anterior/posterior axis, embryo)|go:"GO:0007427"(epithelial cell migration, open tracheal system)|go:"GO:0008270"(zinc ion binding)|dip:DIP-17716N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2017/08/06 2017/08/10 rogid:oSo29NrCWIeCi2OMusohCk64uiw7227 rogid:zPloouLNEALRKuLvtZc0jT4RZu07227 rigid:GULCyZPZE1EhAbW+dP0E1YGtm5I false - his tag:n-n - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P14003 uniprotkb:P16371 intact:EBI-123011|intact:EBI-1639662|uniprotkb:A4V1N7|uniprotkb:Q95NH3|uniprotkb:Q95NU9|uniprotkb:Q9VSN8|ensemblmetazoa:FBpp0076296|ensemblmetazoa:FBpp0099504 intact:EBI-153866|intact:EBI-1639108|uniprotkb:Q0KI08|uniprotkb:Q7KRZ4|uniprotkb:Q9V3F7|uniprotkb:A4V3F6|ensemblmetazoa:FBpp0089115 psi-mi:hair_drome(display_long)|uniprotkb:CG6494(orf name)|uniprotkb:h(gene name)|psi-mi:h(display_short) psi-mi:grou_drome(display_long)|uniprotkb:gro(gene name)|psi-mi:gro(display_short)|uniprotkb:"E(spl)m9/m10"(gene name synonym)|uniprotkb:CG8384(orf name)|uniprotkb:Enhancer of split m9/10 protein(gene name synonym) psi-mi:"MI:0096"(pull down) Payankaulam et al. (2009) pubmed:19805071|doi:10.1073/pnas.0904507106|imex:IM-14845 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15804943|dip:DIP-344E|imex:IM-14845-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001014577.1|refseq:NP_523977.2|flybase:FBgn0001168|ensemblmetazoa:FBgn0001168(gene)|ensemblmetazoa:FBtr0076569(transcript)|ensemblmetazoa:FBtr0100153(transcript)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0035290"(trunk segmentation)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0061024"(membrane organization)|go:"GO:0070888"(E-box binding)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|mint:P14003|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001666"(response to hypoxia)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007366"(periodic partitioning by pair rule gene)|go:"GO:0007399"(nervous system development)|go:"GO:0007424"(open tracheal system development)|go:"GO:0007435"(salivary gland morphogenesis)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0031323"(regulation of cellular metabolic process)|go:"GO:0035239"(tube morphogenesis)|go:"GO:0035289"(posterior head segmentation)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|dip:DIP-637N refseq:NP_001189293.1|refseq:NP_524514.2|refseq:NP_733133.1|refseq:NP_733134.1|refseq:NP_733135.1|refseq:NP_996298.1|flybase:FBgn0001139|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071837"(HMG box domain binding)|go:"GO:0071906"(CRD domain binding)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR005617(Groucho/TLE, N-terminal Q-rich region)|interpro:IPR009146(Groucho/transducin-like enhancer)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|mint:P16371|reactome:R-DME-201722|reactome:R-DME-209421|reactome:R-DME-209441|reactome:R-DME-3769402|reactome:R-DME-4641265|go:"GO:0045751"(negative regulation of Toll signaling pathway)|ensemblmetazoa:FBgn0001139(gene)|ensemblmetazoa:FBtr0084966(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007399"(nervous system development)|go:"GO:0007541"("sex determination, primary response to X:A ratio")|go:"GO:0008134"(transcription factor binding)|go:"GO:0008293"(torso signaling pathway)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030154"(cell differentiation)|go:"GO:0032991"(protein-containing complex)|dip:DIP-40N psi-mi:"MI:0465"(dip) - - dip-version:1|dip-updated-by:nodeMerge04|dip-date-update:2011-10-17|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/06 2017/08/10 rogid:bO023bTsk72HhqvmgSjLEIotrDw7227 rogid:oSo29NrCWIeCi2OMusohCk64uiw7227 rigid:FHdrglr3JteKqIwUuxGzJp7BT8k false glutathione s tranferase tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P10734 uniprotkb:O46036 intact:EBI-170297|intact:EBI-1630197|uniprotkb:Q540X6|uniprotkb:Q9VPC6|ensemblmetazoa:FBpp0077941 intact:EBI-159330|uniprotkb:O61283|uniprotkb:Q59DX5|ensemblmetazoa:FBpp0099514|uniprotkb:Q95SQ8|uniprotkb:Q9VG02 psi-mi:knir_drome(display_long)|uniprotkb:kni(gene name)|psi-mi:kni(display_short)|uniprotkb:NR0A1(gene name synonym)|uniprotkb:CG4717(orf name)|uniprotkb:Nuclear receptor subfamily 0 group A member 1(gene name synonym) psi-mi:ctbp_drome(display_long)|uniprotkb:CtBP(gene name)|psi-mi:CtBP(display_short)|uniprotkb:CG7583(orf name)|uniprotkb:dCtBP(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Payankaulam et al. (2009) pubmed:19805071|doi:10.1073/pnas.0904507106|imex:IM-14845 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15804923|imex:IM-14845-6|dip:DIP-104160E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524187.1|flybase:FBgn0001320|ensemblmetazoa:FBgn0001320(gene)|go:"GO:0035290"(trunk segmentation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|ensemblmetazoa:FBtr0078283(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0007354"(zygotic determination of anterior/posterior axis, embryo)|go:"GO:0007427"(epithelial cell migration, open tracheal system)|go:"GO:0008270"(zinc ion binding)|dip:DIP-17716N refseq:NP_001014617.1|refseq:NP_524336.2|refseq:NP_731762.1|refseq:NP_731763.1|refseq:NP_731764.1|flybase:FBgn0020496|go:"GO:0016360"(sensory organ precursor cell fate determination)|go:"GO:0016616"(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|go:"GO:0022416"(chaeta development)|go:"GO:0031010"(ISWI-type complex)|go:"GO:0035220"(wing disc development)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043044"|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051287"(NAD binding)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR006139(D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region)|interpro:IPR006140(D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding)|interpro:IPR029753|interpro:IPR036291|interpro:IPR043322|mint:O46036|reactome:R-DME-3769402|go:"GO:0008134"(transcription factor binding)|ensemblmetazoa:FBgn0020496(gene)|ensemblmetazoa:FBtr0100161(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|reactome:R-DME-3899300|reactome:R-DME-4641265|refseq:NP_001262520.1|dip:DIP-17268N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2017/08/06 2017/08/10 rogid:zPloouLNEALRKuLvtZc0jT4RZu07227 rogid:hbMeldNlirFwVr+5QX9bGiPqZ1w7227 rigid:3BeDGZoicIjE7SCs8wDSi16so/0 false flag tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P10734 uniprotkb:P16371 intact:EBI-170297|intact:EBI-1630197|uniprotkb:Q540X6|uniprotkb:Q9VPC6|ensemblmetazoa:FBpp0077941 intact:EBI-153866|intact:EBI-1639108|uniprotkb:Q0KI08|uniprotkb:Q7KRZ4|uniprotkb:Q9V3F7|uniprotkb:A4V3F6|ensemblmetazoa:FBpp0089115 psi-mi:knir_drome(display_long)|uniprotkb:kni(gene name)|psi-mi:kni(display_short)|uniprotkb:NR0A1(gene name synonym)|uniprotkb:CG4717(orf name)|uniprotkb:Nuclear receptor subfamily 0 group A member 1(gene name synonym) psi-mi:grou_drome(display_long)|uniprotkb:gro(gene name)|psi-mi:gro(display_short)|uniprotkb:"E(spl)m9/m10"(gene name synonym)|uniprotkb:CG8384(orf name)|uniprotkb:Enhancer of split m9/10 protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Payankaulam et al. (2009) pubmed:19805071|doi:10.1073/pnas.0904507106|imex:IM-14845 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15804923|imex:IM-14845-6|dip:DIP-104160E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524187.1|flybase:FBgn0001320|ensemblmetazoa:FBgn0001320(gene)|go:"GO:0035290"(trunk segmentation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|ensemblmetazoa:FBtr0078283(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0007354"(zygotic determination of anterior/posterior axis, embryo)|go:"GO:0007427"(epithelial cell migration, open tracheal system)|go:"GO:0008270"(zinc ion binding)|dip:DIP-17716N refseq:NP_001189293.1|refseq:NP_524514.2|refseq:NP_733133.1|refseq:NP_733134.1|refseq:NP_733135.1|refseq:NP_996298.1|flybase:FBgn0001139|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071837"(HMG box domain binding)|go:"GO:0071906"(CRD domain binding)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR005617(Groucho/TLE, N-terminal Q-rich region)|interpro:IPR009146(Groucho/transducin-like enhancer)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|mint:P16371|reactome:R-DME-201722|reactome:R-DME-209421|reactome:R-DME-209441|reactome:R-DME-3769402|reactome:R-DME-4641265|go:"GO:0045751"(negative regulation of Toll signaling pathway)|ensemblmetazoa:FBgn0001139(gene)|ensemblmetazoa:FBtr0084966(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007399"(nervous system development)|go:"GO:0007541"("sex determination, primary response to X:A ratio")|go:"GO:0008134"(transcription factor binding)|go:"GO:0008293"(torso signaling pathway)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030154"(cell differentiation)|go:"GO:0032991"(protein-containing complex)|dip:DIP-40N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2017/08/06 2017/08/10 rogid:zPloouLNEALRKuLvtZc0jT4RZu07227 rogid:oSo29NrCWIeCi2OMusohCk64uiw7227 rigid:3BeDGZoicIjE7SCs8wDSi16so/0 false flag tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P16371 uniprotkb:P10734 intact:EBI-153866|intact:EBI-1639108|uniprotkb:Q0KI08|uniprotkb:Q7KRZ4|uniprotkb:Q9V3F7|uniprotkb:A4V3F6|ensemblmetazoa:FBpp0089115 intact:EBI-170297|intact:EBI-1630197|uniprotkb:Q540X6|uniprotkb:Q9VPC6|ensemblmetazoa:FBpp0077941 psi-mi:grou_drome(display_long)|uniprotkb:gro(gene name)|psi-mi:gro(display_short)|uniprotkb:"E(spl)m9/m10"(gene name synonym)|uniprotkb:CG8384(orf name)|uniprotkb:Enhancer of split m9/10 protein(gene name synonym) psi-mi:knir_drome(display_long)|uniprotkb:kni(gene name)|psi-mi:kni(display_short)|uniprotkb:NR0A1(gene name synonym)|uniprotkb:CG4717(orf name)|uniprotkb:Nuclear receptor subfamily 0 group A member 1(gene name synonym) psi-mi:"MI:0096"(pull down) Payankaulam et al. (2009) pubmed:19805071|doi:10.1073/pnas.0904507106|imex:IM-14845 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15804902|imex:IM-14845-5|dip:DIP-104159E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001189293.1|refseq:NP_524514.2|refseq:NP_733133.1|refseq:NP_733134.1|refseq:NP_733135.1|refseq:NP_996298.1|flybase:FBgn0001139|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071837"(HMG box domain binding)|go:"GO:0071906"(CRD domain binding)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR005617(Groucho/TLE, N-terminal Q-rich region)|interpro:IPR009146(Groucho/transducin-like enhancer)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|mint:P16371|reactome:R-DME-201722|reactome:R-DME-209421|reactome:R-DME-209441|reactome:R-DME-3769402|reactome:R-DME-4641265|go:"GO:0045751"(negative regulation of Toll signaling pathway)|ensemblmetazoa:FBgn0001139(gene)|ensemblmetazoa:FBtr0084966(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007399"(nervous system development)|go:"GO:0007541"("sex determination, primary response to X:A ratio")|go:"GO:0008134"(transcription factor binding)|go:"GO:0008293"(torso signaling pathway)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030154"(cell differentiation)|go:"GO:0032991"(protein-containing complex)|dip:DIP-40N refseq:NP_524187.1|flybase:FBgn0001320|ensemblmetazoa:FBgn0001320(gene)|go:"GO:0035290"(trunk segmentation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|ensemblmetazoa:FBtr0078283(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0007354"(zygotic determination of anterior/posterior axis, embryo)|go:"GO:0007427"(epithelial cell migration, open tracheal system)|go:"GO:0008270"(zinc ion binding)|dip:DIP-17716N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/06 2017/08/10 rogid:oSo29NrCWIeCi2OMusohCk64uiw7227 rogid:zPloouLNEALRKuLvtZc0jT4RZu07227 rigid:GULCyZPZE1EhAbW+dP0E1YGtm5I false - glutathione s tranferase tag:n-n|sufficient binding region:139-330 - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) uniprotkb:P14003 uniprotkb:P16371 intact:EBI-123011|intact:EBI-1639662|uniprotkb:A4V1N7|uniprotkb:Q95NH3|uniprotkb:Q95NU9|uniprotkb:Q9VSN8|ensemblmetazoa:FBpp0076296|ensemblmetazoa:FBpp0099504 intact:EBI-153866|intact:EBI-1639108|uniprotkb:Q0KI08|uniprotkb:Q7KRZ4|uniprotkb:Q9V3F7|uniprotkb:A4V3F6|ensemblmetazoa:FBpp0089115 psi-mi:hair_drome(display_long)|uniprotkb:CG6494(orf name)|uniprotkb:h(gene name)|psi-mi:h(display_short) psi-mi:grou_drome(display_long)|uniprotkb:gro(gene name)|psi-mi:gro(display_short)|uniprotkb:"E(spl)m9/m10"(gene name synonym)|uniprotkb:CG8384(orf name)|uniprotkb:Enhancer of split m9/10 protein(gene name synonym) psi-mi:"MI:0096"(pull down) Payankaulam et al. (2009) pubmed:19805071|doi:10.1073/pnas.0904507106|imex:IM-14845 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15804883|dip:DIP-75973E|imex:IM-14845-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001014577.1|refseq:NP_523977.2|flybase:FBgn0001168|ensemblmetazoa:FBgn0001168(gene)|ensemblmetazoa:FBtr0076569(transcript)|ensemblmetazoa:FBtr0100153(transcript)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0035290"(trunk segmentation)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0061024"(membrane organization)|go:"GO:0070888"(E-box binding)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|mint:P14003|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001666"(response to hypoxia)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007366"(periodic partitioning by pair rule gene)|go:"GO:0007399"(nervous system development)|go:"GO:0007424"(open tracheal system development)|go:"GO:0007435"(salivary gland morphogenesis)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0031323"(regulation of cellular metabolic process)|go:"GO:0035239"(tube morphogenesis)|go:"GO:0035289"(posterior head segmentation)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|dip:DIP-637N refseq:NP_001189293.1|refseq:NP_524514.2|refseq:NP_733133.1|refseq:NP_733134.1|refseq:NP_733135.1|refseq:NP_996298.1|flybase:FBgn0001139|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071837"(HMG box domain binding)|go:"GO:0071906"(CRD domain binding)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR005617(Groucho/TLE, N-terminal Q-rich region)|interpro:IPR009146(Groucho/transducin-like enhancer)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|mint:P16371|reactome:R-DME-201722|reactome:R-DME-209421|reactome:R-DME-209441|reactome:R-DME-3769402|reactome:R-DME-4641265|go:"GO:0045751"(negative regulation of Toll signaling pathway)|ensemblmetazoa:FBgn0001139(gene)|ensemblmetazoa:FBtr0084966(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007399"(nervous system development)|go:"GO:0007541"("sex determination, primary response to X:A ratio")|go:"GO:0008134"(transcription factor binding)|go:"GO:0008293"(torso signaling pathway)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030154"(cell differentiation)|go:"GO:0032991"(protein-containing complex)|dip:DIP-40N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/06 2017/08/10 rogid:bO023bTsk72HhqvmgSjLEIotrDw7227 rogid:oSo29NrCWIeCi2OMusohCk64uiw7227 rigid:FHdrglr3JteKqIwUuxGzJp7BT8k false glutathione s tranferase tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P14003 uniprotkb:P16371 intact:EBI-123011|intact:EBI-1639662|uniprotkb:A4V1N7|uniprotkb:Q95NH3|uniprotkb:Q95NU9|uniprotkb:Q9VSN8|ensemblmetazoa:FBpp0076296|ensemblmetazoa:FBpp0099504 intact:EBI-153866|intact:EBI-1639108|uniprotkb:Q0KI08|uniprotkb:Q7KRZ4|uniprotkb:Q9V3F7|uniprotkb:A4V3F6|ensemblmetazoa:FBpp0089115 psi-mi:hair_drome(display_long)|uniprotkb:CG6494(orf name)|uniprotkb:h(gene name)|psi-mi:h(display_short) psi-mi:grou_drome(display_long)|uniprotkb:gro(gene name)|psi-mi:gro(display_short)|uniprotkb:"E(spl)m9/m10"(gene name synonym)|uniprotkb:CG8384(orf name)|uniprotkb:Enhancer of split m9/10 protein(gene name synonym) psi-mi:"MI:0096"(pull down) Payankaulam et al. (2009) pubmed:19805071|doi:10.1073/pnas.0904507106|imex:IM-14845 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15804965|dip:DIP-344E|imex:IM-14845-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001014577.1|refseq:NP_523977.2|flybase:FBgn0001168|ensemblmetazoa:FBgn0001168(gene)|ensemblmetazoa:FBtr0076569(transcript)|ensemblmetazoa:FBtr0100153(transcript)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0035290"(trunk segmentation)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0061024"(membrane organization)|go:"GO:0070888"(E-box binding)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|mint:P14003|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001666"(response to hypoxia)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007366"(periodic partitioning by pair rule gene)|go:"GO:0007399"(nervous system development)|go:"GO:0007424"(open tracheal system development)|go:"GO:0007435"(salivary gland morphogenesis)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0031323"(regulation of cellular metabolic process)|go:"GO:0035239"(tube morphogenesis)|go:"GO:0035289"(posterior head segmentation)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|dip:DIP-637N refseq:NP_001189293.1|refseq:NP_524514.2|refseq:NP_733133.1|refseq:NP_733134.1|refseq:NP_733135.1|refseq:NP_996298.1|flybase:FBgn0001139|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071837"(HMG box domain binding)|go:"GO:0071906"(CRD domain binding)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR005617(Groucho/TLE, N-terminal Q-rich region)|interpro:IPR009146(Groucho/transducin-like enhancer)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|mint:P16371|reactome:R-DME-201722|reactome:R-DME-209421|reactome:R-DME-209441|reactome:R-DME-3769402|reactome:R-DME-4641265|go:"GO:0045751"(negative regulation of Toll signaling pathway)|ensemblmetazoa:FBgn0001139(gene)|ensemblmetazoa:FBtr0084966(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007399"(nervous system development)|go:"GO:0007541"("sex determination, primary response to X:A ratio")|go:"GO:0008134"(transcription factor binding)|go:"GO:0008293"(torso signaling pathway)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030154"(cell differentiation)|go:"GO:0032991"(protein-containing complex)|dip:DIP-40N psi-mi:"MI:0465"(dip) - - dip-version:1|dip-updated-by:nodeMerge04|dip-date-update:2014-07-01|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/06 2017/08/10 rogid:bO023bTsk72HhqvmgSjLEIotrDw7227 rogid:oSo29NrCWIeCi2OMusohCk64uiw7227 rigid:FHdrglr3JteKqIwUuxGzJp7BT8k false glutathione s tranferase tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)