#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q96CV9 uniprotkb:Q29122 intact:EBI-748974|uniprotkb:Q5T672|uniprotkb:Q5T673|uniprotkb:Q5T674|uniprotkb:Q5T675|uniprotkb:Q7LDL9|uniprotkb:Q8N562|uniprotkb:Q9UET9|uniprotkb:Q9UEV4|uniprotkb:Q9Y218|uniprotkb:B3KP00|uniprotkb:D3DRS4|uniprotkb:D3DRS8|ensembl:ENSP00000263036|ensembl:ENSP00000368021|ensembl:ENSP00000368022|ensembl:ENSP00000368032 intact:EBI-15804516 psi-mi:optn_human(display_long)|uniprotkb:HYPL(gene name synonym)|uniprotkb:Optic neuropathy-inducing protein(gene name synonym)|uniprotkb:E3-14.7K-interacting protein(gene name synonym)|uniprotkb:FIP-2(gene name synonym)|uniprotkb:Huntingtin-interacting protein L(gene name synonym)|uniprotkb:Huntingtin yeast partner L(gene name synonym)|uniprotkb:NEMO-related protein(gene name synonym)|uniprotkb:Transcription factor IIIA-interacting protein(gene name synonym)|uniprotkb:OPTN(gene name)|psi-mi:OPTN(display_short)|uniprotkb:FIP2(gene name synonym)|uniprotkb:GLC1E(gene name synonym)|uniprotkb:NRP(gene name synonym)|uniprotkb:HIP7(gene name synonym)|uniprotkb:Huntingtin-interacting protein 7(gene name synonym) psi-mi:myo6_pig(display_long)|uniprotkb:MYO6(gene name)|psi-mi:MYO6(display_short)|uniprotkb:Unconventional myosin-6(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Phichith et al. (2009) pubmed:19805065|doi:10.1073/pnas.0909748106|imex:IM-14844 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9823(pig)|taxid:9823("Sus scrofa (Pig)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15804564|imex:IM-14844-1|dip:DIP-104157E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001008212.1|refseq:NP_001008213.1|refseq:NP_001008214.1|refseq:NP_068815.2|ensembl:ENSG00000123240(gene)|ensembl:ENST00000263036(transcript)|ensembl:ENST00000378747(transcript)|ensembl:ENST00000378748(transcript)|ensembl:ENST00000378757(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001920"(negative regulation of receptor recycling)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0007030"(Golgi organization)|go:"GO:0007165"(signal transduction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008219"(cell death)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0061734"(parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:1904417"(positive regulation of xenophagy)|interpro:IPR021063|interpro:IPR032419|interpro:IPR032939|interpro:IPR034735|mint:Q96CV9|rcsb pdb:2LO4|rcsb pdb:2LUE|rcsb pdb:3VTV|rcsb pdb:3VTW|rcsb pdb:5AAZ|rcsb pdb:5B83|rcsb pdb:5EOA|rcsb pdb:5EOF|rcsb pdb:7CZM|reactome:R-HSA-2565942|reactome:R-HSA-8854214|dip:DIP-42001N go:"GO:0000146"(microfilament motor activity)|go:"GO:0001726"(ruffle)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005938"(cell cortex)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006897"(endocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016459"(myosin complex)|go:"GO:0016591"(RNA polymerase II, holoenzyme)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030175"(filopodium)|go:"GO:0030330"(DNA damage response, signal transduction by p53 class mediator)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031941"(filamentous actin)|go:"GO:0031965"(nuclear membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032587"(ruffle membrane)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042491"(inner ear auditory receptor cell differentiation)|go:"GO:0043531"(ADP binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051015"(actin filament binding)|go:"GO:0051046"(regulation of secretion)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR008989(Myosin S1 fragment, N-terminal)|interpro:IPR027417|interpro:IPR032412|interpro:IPR036114|interpro:IPR036961|rcsb pdb:2BKH|rcsb pdb:2BKI|rcsb pdb:2V26|rcsb pdb:2VAS|rcsb pdb:2VB6|rcsb pdb:2X51|rcsb pdb:3GN4|rcsb pdb:3L9I|rcsb pdb:4ANJ|rcsb pdb:4DBP|rcsb pdb:4DBQ|rcsb pdb:4DBR|rcsb pdb:5O2L|rcsb pdb:6BNP|rcsb pdb:6BNQ|rcsb pdb:6BNV|rcsb pdb:6BNW|refseq:NP_999186.1|dip:DIP-48994N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/06 2018/04/06 rogid:jcCTXDx1bJq3K5mgNUD73jeWeBU9606 rogid:g/zSVaBhSP38cm3mLDSVUGCM/8Q9823 rigid:0QmdAXhxOtX/U7NQ0CzuSXHMTMg false - flag tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q96CV9 uniprotkb:Q29122 intact:EBI-748974|uniprotkb:Q5T672|uniprotkb:Q5T673|uniprotkb:Q5T674|uniprotkb:Q5T675|uniprotkb:Q7LDL9|uniprotkb:Q8N562|uniprotkb:Q9UET9|uniprotkb:Q9UEV4|uniprotkb:Q9Y218|uniprotkb:B3KP00|uniprotkb:D3DRS4|uniprotkb:D3DRS8|ensembl:ENSP00000263036|ensembl:ENSP00000368021|ensembl:ENSP00000368022|ensembl:ENSP00000368032 intact:EBI-15804516 psi-mi:optn_human(display_long)|uniprotkb:HYPL(gene name synonym)|uniprotkb:Optic neuropathy-inducing protein(gene name synonym)|uniprotkb:E3-14.7K-interacting protein(gene name synonym)|uniprotkb:FIP-2(gene name synonym)|uniprotkb:Huntingtin-interacting protein L(gene name synonym)|uniprotkb:Huntingtin yeast partner L(gene name synonym)|uniprotkb:NEMO-related protein(gene name synonym)|uniprotkb:Transcription factor IIIA-interacting protein(gene name synonym)|uniprotkb:OPTN(gene name)|psi-mi:OPTN(display_short)|uniprotkb:FIP2(gene name synonym)|uniprotkb:GLC1E(gene name synonym)|uniprotkb:NRP(gene name synonym)|uniprotkb:HIP7(gene name synonym)|uniprotkb:Huntingtin-interacting protein 7(gene name synonym) psi-mi:myo6_pig(display_long)|uniprotkb:MYO6(gene name)|psi-mi:MYO6(display_short)|uniprotkb:Unconventional myosin-6(gene name synonym) psi-mi:"MI:0040"(electron microscopy) Phichith et al. (2009) pubmed:19805065|doi:10.1073/pnas.0909748106|imex:IM-14844 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9823(pig)|taxid:9823("Sus scrofa (Pig)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15804583|imex:IM-14844-2|dip:DIP-104157E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001008212.1|refseq:NP_001008213.1|refseq:NP_001008214.1|refseq:NP_068815.2|ensembl:ENSG00000123240(gene)|ensembl:ENST00000263036(transcript)|ensembl:ENST00000378747(transcript)|ensembl:ENST00000378748(transcript)|ensembl:ENST00000378757(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001920"(negative regulation of receptor recycling)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0007030"(Golgi organization)|go:"GO:0007165"(signal transduction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008219"(cell death)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0061734"(parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:1904417"(positive regulation of xenophagy)|interpro:IPR021063|interpro:IPR032419|interpro:IPR032939|interpro:IPR034735|mint:Q96CV9|rcsb pdb:2LO4|rcsb pdb:2LUE|rcsb pdb:3VTV|rcsb pdb:3VTW|rcsb pdb:5AAZ|rcsb pdb:5B83|rcsb pdb:5EOA|rcsb pdb:5EOF|rcsb pdb:7CZM|reactome:R-HSA-2565942|reactome:R-HSA-8854214|dip:DIP-42001N go:"GO:0000146"(microfilament motor activity)|go:"GO:0001726"(ruffle)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005938"(cell cortex)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006897"(endocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016459"(myosin complex)|go:"GO:0016591"(RNA polymerase II, holoenzyme)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030175"(filopodium)|go:"GO:0030330"(DNA damage response, signal transduction by p53 class mediator)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031941"(filamentous actin)|go:"GO:0031965"(nuclear membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032587"(ruffle membrane)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042491"(inner ear auditory receptor cell differentiation)|go:"GO:0043531"(ADP binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051015"(actin filament binding)|go:"GO:0051046"(regulation of secretion)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR008989(Myosin S1 fragment, N-terminal)|interpro:IPR027417|interpro:IPR032412|interpro:IPR036114|interpro:IPR036961|rcsb pdb:2BKH|rcsb pdb:2BKI|rcsb pdb:2V26|rcsb pdb:2VAS|rcsb pdb:2VB6|rcsb pdb:2X51|rcsb pdb:3GN4|rcsb pdb:3L9I|rcsb pdb:4ANJ|rcsb pdb:4DBP|rcsb pdb:4DBQ|rcsb pdb:4DBR|rcsb pdb:5O2L|rcsb pdb:6BNP|rcsb pdb:6BNQ|rcsb pdb:6BNV|rcsb pdb:6BNW|refseq:NP_999186.1|dip:DIP-48994N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/06 2018/04/06 rogid:jcCTXDx1bJq3K5mgNUD73jeWeBU9606 rogid:g/zSVaBhSP38cm3mLDSVUGCM/8Q9823 rigid:0QmdAXhxOtX/U7NQ0CzuSXHMTMg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q96CV9 uniprotkb:Q29122 intact:EBI-748974|uniprotkb:Q5T672|uniprotkb:Q5T673|uniprotkb:Q5T674|uniprotkb:Q5T675|uniprotkb:Q7LDL9|uniprotkb:Q8N562|uniprotkb:Q9UET9|uniprotkb:Q9UEV4|uniprotkb:Q9Y218|uniprotkb:B3KP00|uniprotkb:D3DRS4|uniprotkb:D3DRS8|ensembl:ENSP00000263036|ensembl:ENSP00000368021|ensembl:ENSP00000368022|ensembl:ENSP00000368032 intact:EBI-15804516 psi-mi:optn_human(display_long)|uniprotkb:HYPL(gene name synonym)|uniprotkb:Optic neuropathy-inducing protein(gene name synonym)|uniprotkb:E3-14.7K-interacting protein(gene name synonym)|uniprotkb:FIP-2(gene name synonym)|uniprotkb:Huntingtin-interacting protein L(gene name synonym)|uniprotkb:Huntingtin yeast partner L(gene name synonym)|uniprotkb:NEMO-related protein(gene name synonym)|uniprotkb:Transcription factor IIIA-interacting protein(gene name synonym)|uniprotkb:OPTN(gene name)|psi-mi:OPTN(display_short)|uniprotkb:FIP2(gene name synonym)|uniprotkb:GLC1E(gene name synonym)|uniprotkb:NRP(gene name synonym)|uniprotkb:HIP7(gene name synonym)|uniprotkb:Huntingtin-interacting protein 7(gene name synonym) psi-mi:myo6_pig(display_long)|uniprotkb:MYO6(gene name)|psi-mi:MYO6(display_short)|uniprotkb:Unconventional myosin-6(gene name synonym) psi-mi:"MI:0107"(surface plasmon resonance) Phichith et al. (2009) pubmed:19805065|doi:10.1073/pnas.0909748106|imex:IM-14844 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9823(pig)|taxid:9823("Sus scrofa (Pig)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15804600|imex:IM-14844-3|dip:DIP-104157E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001008212.1|refseq:NP_001008213.1|refseq:NP_001008214.1|refseq:NP_068815.2|ensembl:ENSG00000123240(gene)|ensembl:ENST00000263036(transcript)|ensembl:ENST00000378747(transcript)|ensembl:ENST00000378748(transcript)|ensembl:ENST00000378757(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001920"(negative regulation of receptor recycling)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0007030"(Golgi organization)|go:"GO:0007165"(signal transduction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008219"(cell death)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0061734"(parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:1904417"(positive regulation of xenophagy)|interpro:IPR021063|interpro:IPR032419|interpro:IPR032939|interpro:IPR034735|mint:Q96CV9|rcsb pdb:2LO4|rcsb pdb:2LUE|rcsb pdb:3VTV|rcsb pdb:3VTW|rcsb pdb:5AAZ|rcsb pdb:5B83|rcsb pdb:5EOA|rcsb pdb:5EOF|rcsb pdb:7CZM|reactome:R-HSA-2565942|reactome:R-HSA-8854214|dip:DIP-42001N go:"GO:0000146"(microfilament motor activity)|go:"GO:0001726"(ruffle)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005938"(cell cortex)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006897"(endocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016459"(myosin complex)|go:"GO:0016591"(RNA polymerase II, holoenzyme)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030175"(filopodium)|go:"GO:0030330"(DNA damage response, signal transduction by p53 class mediator)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031941"(filamentous actin)|go:"GO:0031965"(nuclear membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032587"(ruffle membrane)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042491"(inner ear auditory receptor cell differentiation)|go:"GO:0043531"(ADP binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051015"(actin filament binding)|go:"GO:0051046"(regulation of secretion)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR008989(Myosin S1 fragment, N-terminal)|interpro:IPR027417|interpro:IPR032412|interpro:IPR036114|interpro:IPR036961|rcsb pdb:2BKH|rcsb pdb:2BKI|rcsb pdb:2V26|rcsb pdb:2VAS|rcsb pdb:2VB6|rcsb pdb:2X51|rcsb pdb:3GN4|rcsb pdb:3L9I|rcsb pdb:4ANJ|rcsb pdb:4DBP|rcsb pdb:4DBQ|rcsb pdb:4DBR|rcsb pdb:5O2L|rcsb pdb:6BNP|rcsb pdb:6BNQ|rcsb pdb:6BNV|rcsb pdb:6BNW|refseq:NP_999186.1|dip:DIP-48994N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/06 2018/04/06 rogid:jcCTXDx1bJq3K5mgNUD73jeWeBU9606 rogid:g/zSVaBhSP38cm3mLDSVUGCM/8Q9823 rigid:0QmdAXhxOtX/U7NQ0CzuSXHMTMg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P98082-1 uniprotkb:Q29122 intact:EBI-15804617|ensembl:ENSP00000313391 intact:EBI-15804516 psi-mi:p98082-1(display_long)|uniprotkb:DAB2(gene name)|psi-mi:DAB2(display_short)|uniprotkb:DOC2(gene name synonym)|uniprotkb:Adaptor molecule disabled-2(gene name synonym)|uniprotkb:Differentially expressed in ovarian carcinoma 2(gene name synonym)|uniprotkb:Differentially-expressed protein 2(gene name synonym) psi-mi:myo6_pig(display_long)|uniprotkb:MYO6(gene name)|psi-mi:MYO6(display_short)|uniprotkb:Unconventional myosin-6(gene name synonym) psi-mi:"MI:0040"(electron microscopy) Phichith et al. (2009) pubmed:19805065|doi:10.1073/pnas.0909748106|imex:IM-14844 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9823(pig)|taxid:9823("Sus scrofa (Pig)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15804626|imex:IM-14844-4|dip:DIP-104158E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000153071(gene)|ensembl:ENST00000320816(transcript)|intact:EBI-1171238(isoform-parent) go:"GO:0000146"(microfilament motor activity)|go:"GO:0001726"(ruffle)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005938"(cell cortex)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006897"(endocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016459"(myosin complex)|go:"GO:0016591"(RNA polymerase II, holoenzyme)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030175"(filopodium)|go:"GO:0030330"(DNA damage response, signal transduction by p53 class mediator)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031941"(filamentous actin)|go:"GO:0031965"(nuclear membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032587"(ruffle membrane)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042491"(inner ear auditory receptor cell differentiation)|go:"GO:0043531"(ADP binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051015"(actin filament binding)|go:"GO:0051046"(regulation of secretion)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR008989(Myosin S1 fragment, N-terminal)|interpro:IPR027417|interpro:IPR032412|interpro:IPR036114|interpro:IPR036961|rcsb pdb:2BKH|rcsb pdb:2BKI|rcsb pdb:2V26|rcsb pdb:2VAS|rcsb pdb:2VB6|rcsb pdb:2X51|rcsb pdb:3GN4|rcsb pdb:3L9I|rcsb pdb:4ANJ|rcsb pdb:4DBP|rcsb pdb:4DBQ|rcsb pdb:4DBR|rcsb pdb:5O2L|rcsb pdb:6BNP|rcsb pdb:6BNQ|rcsb pdb:6BNV|rcsb pdb:6BNW|refseq:NP_999186.1|dip:DIP-48994N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/06 2017/08/10 rogid:DLo0+0XUrWaKw1ycCrIefyVK/YM9606 rogid:g/zSVaBhSP38cm3mLDSVUGCM/8Q9823 rigid:OP+3Gfv4YXuAyQxrfI5li6zQBfU false binding-associated region:440-770 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P98082-1 uniprotkb:Q29122 intact:EBI-15804617|ensembl:ENSP00000313391 intact:EBI-15804516 psi-mi:p98082-1(display_long)|uniprotkb:DAB2(gene name)|psi-mi:DAB2(display_short)|uniprotkb:DOC2(gene name synonym)|uniprotkb:Adaptor molecule disabled-2(gene name synonym)|uniprotkb:Differentially expressed in ovarian carcinoma 2(gene name synonym)|uniprotkb:Differentially-expressed protein 2(gene name synonym) psi-mi:myo6_pig(display_long)|uniprotkb:MYO6(gene name)|psi-mi:MYO6(display_short)|uniprotkb:Unconventional myosin-6(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Phichith et al. (2009) pubmed:19805065|doi:10.1073/pnas.0909748106|imex:IM-14844 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9823(pig)|taxid:9823("Sus scrofa (Pig)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15804645|imex:IM-14844-5|dip:DIP-104158E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000153071(gene)|ensembl:ENST00000320816(transcript)|intact:EBI-1171238(isoform-parent) go:"GO:0000146"(microfilament motor activity)|go:"GO:0001726"(ruffle)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005938"(cell cortex)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006897"(endocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016459"(myosin complex)|go:"GO:0016591"(RNA polymerase II, holoenzyme)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030175"(filopodium)|go:"GO:0030330"(DNA damage response, signal transduction by p53 class mediator)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031941"(filamentous actin)|go:"GO:0031965"(nuclear membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032587"(ruffle membrane)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042491"(inner ear auditory receptor cell differentiation)|go:"GO:0043531"(ADP binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051015"(actin filament binding)|go:"GO:0051046"(regulation of secretion)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR008989(Myosin S1 fragment, N-terminal)|interpro:IPR027417|interpro:IPR032412|interpro:IPR036114|interpro:IPR036961|rcsb pdb:2BKH|rcsb pdb:2BKI|rcsb pdb:2V26|rcsb pdb:2VAS|rcsb pdb:2VB6|rcsb pdb:2X51|rcsb pdb:3GN4|rcsb pdb:3L9I|rcsb pdb:4ANJ|rcsb pdb:4DBP|rcsb pdb:4DBQ|rcsb pdb:4DBR|rcsb pdb:5O2L|rcsb pdb:6BNP|rcsb pdb:6BNQ|rcsb pdb:6BNV|rcsb pdb:6BNW|refseq:NP_999186.1|dip:DIP-48994N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/06 2017/08/10 rogid:DLo0+0XUrWaKw1ycCrIefyVK/YM9606 rogid:g/zSVaBhSP38cm3mLDSVUGCM/8Q9823 rigid:OP+3Gfv4YXuAyQxrfI5li6zQBfU false binding-associated region:440-770 flag tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)