#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q76929 uniprotkb:P62940 intact:EBI-15803105 intact:EBI-15803067|ensembl:ENSMMUP00000021879|uniprotkb:P05092|uniprotkb:Q0ZQK4|uniprotkb:Q96IX3|uniprotkb:Q9BRU4|uniprotkb:Q9BTY9|uniprotkb:Q9UC61 psi-mi:q76929_9hiv2(display_long)|uniprotkb:gag(gene name)|psi-mi:gag(display_short) psi-mi:ppia_macmu(display_long)|uniprotkb:PPIA(gene name)|psi-mi:PPIA(display_short)|uniprotkb:CYPA(gene name synonym)|uniprotkb:Cyclophilin A(gene name synonym)|uniprotkb:Cyclosporin A-binding protein(gene name synonym)|uniprotkb:Rotamase A(gene name synonym) psi-mi:"MI:0065"(isothermal titration calorimetry) Price et al. (2009) pubmed:19767750|doi:10.1038/nsmb.1667|imex:IM-14316 taxid:11709(9hiv2)|taxid:11709(Human immunodeficiency virus 2) taxid:9544(macmu)|taxid:9544("Macaca mulatta (Rhesus macaque)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15803118|imex:IM-14316-1|dip:DIP-103218E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005198"(structural molecule activity)|go:"GO:0016032"(viral process)|go:"GO:0019013"(viral nucleocapsid)|interpro:IPR000071(Immunodeficiency lentiviral matrix, N-terminal)|interpro:IPR000721(Retroviral nucleocapsid protein Gag)|interpro:IPR008919(Retrovirus capsid, N-terminal core)|interpro:IPR010999(Retroviral matrix, N-terminal)|interpro:IPR012344(Lentiviral and alpha-retroviral matrix protein, N-terminal)|dip:DIP-48566N ensembl:ENSMMUG00000016638(gene)|ensembl:ENSMMUT00000023383(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005178"(integrin binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006915"(apoptotic process)|go:"GO:0016018"(cyclosporin A binding)|go:"GO:0030168"(platelet activation)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0030595"(leukocyte chemotaxis)|go:"GO:0032148"(activation of protein kinase B activity)|go:"GO:0032873"(negative regulation of stress-activated MAPK cascade)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034389"(lipid droplet organization)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0042118"(endothelial cell activation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045069"(regulation of viral genome replication)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0060352"(cell adhesion molecule production)|go:"GO:0061944"(negative regulation of protein K48-linked ubiquitination)|go:"GO:0070527"(platelet aggregation)|go:"GO:1902176"(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903901"(negative regulation of viral life cycle)|go:"GO:1904399"(heparan sulfate binding)|go:"GO:2001233"(regulation of apoptotic signaling pathway)|interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|interpro:IPR020892|interpro:IPR024936|interpro:IPR029000|rcsb pdb:2WLW|rcsb pdb:4DGA|rcsb pdb:4DGB|rcsb pdb:4DGC|rcsb pdb:4DGD|rcsb pdb:4DGE|refseq:NP_001027981.1|dip:DIP-48565N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/06 2017/08/10 rogid:TyaX4GI/Opb8712+YoSOjy0MA/c11709 rogid:dr4EVxcO+sqTPBqsQcydRn+rHoo9544 rigid:HqMIOfd7HE96rksg5QFeYwmnH5M false binding-associated region:99-242 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q72497 uniprotkb:P62940 intact:EBI-1036263 intact:EBI-15803067|ensembl:ENSMMUP00000021879|uniprotkb:P05092|uniprotkb:Q0ZQK4|uniprotkb:Q96IX3|uniprotkb:Q9BRU4|uniprotkb:Q9BTY9|uniprotkb:Q9UC61 psi-mi:q72497_9hiv1(display_long)|uniprotkb:gag(gene name)|psi-mi:gag(display_short) psi-mi:ppia_macmu(display_long)|uniprotkb:PPIA(gene name)|psi-mi:PPIA(display_short)|uniprotkb:CYPA(gene name synonym)|uniprotkb:Cyclophilin A(gene name synonym)|uniprotkb:Cyclosporin A-binding protein(gene name synonym)|uniprotkb:Rotamase A(gene name synonym) psi-mi:"MI:0065"(isothermal titration calorimetry) Price et al. (2009) pubmed:19767750|doi:10.1038/nsmb.1667|imex:IM-14316 taxid:11676(9hiv1)|taxid:11676(Human immunodeficiency virus 1) taxid:9544(macmu)|taxid:9544("Macaca mulatta (Rhesus macaque)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15803137|imex:IM-14316-2|dip:DIP-103219E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0042025"(host cell nucleus)|interpro:IPR000071(Immunodeficiency lentiviral matrix, N-terminal)|interpro:IPR000721(Retroviral nucleocapsid protein Gag)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR008916(Retrovirus capsid, C-terminal)|interpro:IPR008919(Retrovirus capsid, N-terminal core)|interpro:IPR010999(Retroviral matrix, N-terminal)|interpro:IPR012344(Lentiviral and alpha-retroviral matrix protein, N-terminal)|interpro:IPR014817(Gag protein p6)|interpro:IPR036875|rcsb pdb:1L6N|rcsb pdb:1M9C|rcsb pdb:1M9E|rcsb pdb:1M9F|rcsb pdb:1M9X|rcsb pdb:3OBX|rcsb pdb:3P0A|rcsb pdb:5I4T|rcsb pdb:5MCZ|rcsb pdb:5MD0|rcsb pdb:5MD1|rcsb pdb:5MD2|rcsb pdb:5MD3|rcsb pdb:5MD4|rcsb pdb:5MD5|rcsb pdb:5MD6|rcsb pdb:5MD7|rcsb pdb:5MD8|rcsb pdb:5MD9|rcsb pdb:5MDA|rcsb pdb:5MDB|rcsb pdb:5MDC|rcsb pdb:5MDD|rcsb pdb:5MDE|rcsb pdb:5MDF|rcsb pdb:5MDG|rcsb pdb:1M9Y|rcsb pdb:3OBU|dip:DIP-36777N ensembl:ENSMMUG00000016638(gene)|ensembl:ENSMMUT00000023383(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005178"(integrin binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006915"(apoptotic process)|go:"GO:0016018"(cyclosporin A binding)|go:"GO:0030168"(platelet activation)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0030595"(leukocyte chemotaxis)|go:"GO:0032148"(activation of protein kinase B activity)|go:"GO:0032873"(negative regulation of stress-activated MAPK cascade)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034389"(lipid droplet organization)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0042118"(endothelial cell activation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045069"(regulation of viral genome replication)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0060352"(cell adhesion molecule production)|go:"GO:0061944"(negative regulation of protein K48-linked ubiquitination)|go:"GO:0070527"(platelet aggregation)|go:"GO:1902176"(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903901"(negative regulation of viral life cycle)|go:"GO:1904399"(heparan sulfate binding)|go:"GO:2001233"(regulation of apoptotic signaling pathway)|interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|interpro:IPR020892|interpro:IPR024936|interpro:IPR029000|rcsb pdb:2WLW|rcsb pdb:4DGA|rcsb pdb:4DGB|rcsb pdb:4DGC|rcsb pdb:4DGD|rcsb pdb:4DGE|refseq:NP_001027981.1|dip:DIP-48565N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/06 2017/08/10 rogid:55IMKXCDcNTefbP49k66GaUdkPs11676 rogid:dr4EVxcO+sqTPBqsQcydRn+rHoo9544 rigid:N1vkQ0RBHp3/+kLOueDBW58kzh4 false binding-associated region:133-278 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)