#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P9WHT9 uniprotkb:P9WHU1 intact:EBI-7947958|uniprotkb:O33245|intact:MINT-7985947|uniprotkb:Q7D7I2|uniprotkb:L0T8V8 intact:EBI-7948002|uniprotkb:O33244|intact:MINT-7985922|uniprotkb:L0T8P4|uniprotkb:Q7D7I3 psi-mi:psb_myctu(display_long)|uniprotkb:Proteasome core protein PrcB(gene name synonym)|uniprotkb:Rv2110c(locus name)|uniprotkb:prcB(gene name)|psi-mi:prcB(display_short)|uniprotkb:20S proteasome beta subunit(gene name synonym) psi-mi:psa_myctu(display_long)|uniprotkb:Proteasome core protein PrcA(gene name synonym)|uniprotkb:Rv2109c(locus name)|uniprotkb:prcA(gene name)|psi-mi:prcA(display_short)|uniprotkb:20S proteasome alpha subunit(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Lin et al. (2009) pubmed:19759536|doi:10.1038/nature08357|imex:IM-16355 taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)") taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15803000|imex:IM-16355-1|dip:DIP-187505E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR029055|refseq:WP_003411023.1|interpro:IPR001353(20S proteasome, A and B subunits)|refseq:NP_216626.1|interpro:IPR023333|interpro:IPR022483|mint:P9WHT9|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0030682"(mitigation of host defenses by symbiont)|go:"GO:0035375"(zymogen binding)|go:"GO:0051603"(proteolysis involved in cellular protein catabolic process)|rcsb pdb:2FHG|rcsb pdb:2FHH|rcsb pdb:2JAY|rcsb pdb:3H6F|rcsb pdb:3H6I|rcsb pdb:3HF9|rcsb pdb:3HFA|rcsb pdb:3KRD|rcsb pdb:3MFE|rcsb pdb:3MI0|rcsb pdb:3MKA|rcsb pdb:5LZP|rcsb pdb:5THO|rcsb pdb:5TRG|rcsb pdb:5TRR|rcsb pdb:5TRS|rcsb pdb:5TRY|rcsb pdb:5TS0|rcsb pdb:6BGL|rcsb pdb:6BGO|rcsb pdb:6OCW|rcsb pdb:6OCZ|rcsb pdb:6ODE rcsb pdb:5LZP|refseq:WP_003906749.1|interpro:IPR029055|rcsb pdb:6BGL|rcsb pdb:6BGO|interpro:IPR001353(20S proteasome, A and B subunits)|rcsb pdb:3MKA|rcsb pdb:3MFE|rcsb pdb:2FHH|rcsb pdb:3MI0|refseq:NP_216625.1|rcsb pdb:3KRD|rcsb pdb:3H6I|rcsb pdb:2FHG|interpro:IPR022296|rcsb pdb:3H6F|rcsb pdb:3HF9|rcsb pdb:3HFA|interpro:IPR023332|rcsb pdb:5TRG|rcsb pdb:5TRR|rcsb pdb:5TRS|rcsb pdb:5TRY|rcsb pdb:5TS0|rcsb pdb:5THO|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005618"(cell wall)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0030682"(mitigation of host defenses by symbiont)|go:"GO:0051603"(proteolysis involved in cellular protein catabolic process)|rcsb pdb:6OCW|rcsb pdb:6OCZ|rcsb pdb:6ODE psi-mi:"MI:0465"(dip) crc64:3FC3FCD81231E129|comment:mint crc64:0356FED74869998A|comment:mint full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/06 2017/08/10 rogid:hQ8Eci/BIL/quaWNhklTdFRPHDI83332 rogid:x+ay7zDnb1yxK8fnu0bFdjkHoS883332 rigid:84Z0Wc2zy2k4ObYyHintX+1EhNs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P9WHT9 uniprotkb:P9WHU1 intact:EBI-7947958|uniprotkb:O33245|intact:MINT-7985947|uniprotkb:Q7D7I2|uniprotkb:L0T8V8 intact:EBI-7948002|uniprotkb:O33244|intact:MINT-7985922|uniprotkb:L0T8P4|uniprotkb:Q7D7I3 psi-mi:psb_myctu(display_long)|uniprotkb:Proteasome core protein PrcB(gene name synonym)|uniprotkb:Rv2110c(locus name)|uniprotkb:prcB(gene name)|psi-mi:prcB(display_short)|uniprotkb:20S proteasome beta subunit(gene name synonym) psi-mi:psa_myctu(display_long)|uniprotkb:Proteasome core protein PrcA(gene name synonym)|uniprotkb:Rv2109c(locus name)|uniprotkb:prcA(gene name)|psi-mi:prcA(display_short)|uniprotkb:20S proteasome alpha subunit(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Lin et al. (2009) pubmed:19759536|doi:10.1038/nature08357|imex:IM-16355 taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)") taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15803021|imex:IM-16355-2|dip:DIP-187505E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR029055|refseq:WP_003411023.1|interpro:IPR001353(20S proteasome, A and B subunits)|refseq:NP_216626.1|interpro:IPR023333|interpro:IPR022483|mint:P9WHT9|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0030682"(mitigation of host defenses by symbiont)|go:"GO:0035375"(zymogen binding)|go:"GO:0051603"(proteolysis involved in cellular protein catabolic process)|rcsb pdb:2FHG|rcsb pdb:2FHH|rcsb pdb:2JAY|rcsb pdb:3H6F|rcsb pdb:3H6I|rcsb pdb:3HF9|rcsb pdb:3HFA|rcsb pdb:3KRD|rcsb pdb:3MFE|rcsb pdb:3MI0|rcsb pdb:3MKA|rcsb pdb:5LZP|rcsb pdb:5THO|rcsb pdb:5TRG|rcsb pdb:5TRR|rcsb pdb:5TRS|rcsb pdb:5TRY|rcsb pdb:5TS0|rcsb pdb:6BGL|rcsb pdb:6BGO|rcsb pdb:6OCW|rcsb pdb:6OCZ|rcsb pdb:6ODE rcsb pdb:5LZP|refseq:WP_003906749.1|interpro:IPR029055|rcsb pdb:6BGL|rcsb pdb:6BGO|interpro:IPR001353(20S proteasome, A and B subunits)|rcsb pdb:3MKA|rcsb pdb:3MFE|rcsb pdb:2FHH|rcsb pdb:3MI0|refseq:NP_216625.1|rcsb pdb:3KRD|rcsb pdb:3H6I|rcsb pdb:2FHG|interpro:IPR022296|rcsb pdb:3H6F|rcsb pdb:3HF9|rcsb pdb:3HFA|interpro:IPR023332|rcsb pdb:5TRG|rcsb pdb:5TRR|rcsb pdb:5TRS|rcsb pdb:5TRY|rcsb pdb:5TS0|rcsb pdb:5THO|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005618"(cell wall)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0030682"(mitigation of host defenses by symbiont)|go:"GO:0051603"(proteolysis involved in cellular protein catabolic process)|rcsb pdb:6OCW|rcsb pdb:6OCZ|rcsb pdb:6ODE psi-mi:"MI:0465"(dip) crc64:3FC3FCD81231E129|comment:mint crc64:0356FED74869998A|comment:mint full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/06 2017/08/10 rogid:hQ8Eci/BIL/quaWNhklTdFRPHDI83332 rogid:x+ay7zDnb1yxK8fnu0bFdjkHoS883332 rigid:84Z0Wc2zy2k4ObYyHintX+1EhNs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P9WHT9 uniprotkb:P9WHU1 intact:EBI-7947958|uniprotkb:O33245|intact:MINT-7985947|uniprotkb:Q7D7I2|uniprotkb:L0T8V8 intact:EBI-7948002|uniprotkb:O33244|intact:MINT-7985922|uniprotkb:L0T8P4|uniprotkb:Q7D7I3 psi-mi:psb_myctu(display_long)|uniprotkb:Proteasome core protein PrcB(gene name synonym)|uniprotkb:Rv2110c(locus name)|uniprotkb:prcB(gene name)|psi-mi:prcB(display_short)|uniprotkb:20S proteasome beta subunit(gene name synonym) psi-mi:psa_myctu(display_long)|uniprotkb:Proteasome core protein PrcA(gene name synonym)|uniprotkb:Rv2109c(locus name)|uniprotkb:prcA(gene name)|psi-mi:prcA(display_short)|uniprotkb:20S proteasome alpha subunit(gene name synonym) psi-mi:"MI:0096"(pull down) Lin et al. (2009) pubmed:19759536|doi:10.1038/nature08357|imex:IM-16355 taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)") taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15803038|imex:IM-16355-3|dip:DIP-187505E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR029055|refseq:WP_003411023.1|interpro:IPR001353(20S proteasome, A and B subunits)|refseq:NP_216626.1|interpro:IPR023333|interpro:IPR022483|mint:P9WHT9|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0030682"(mitigation of host defenses by symbiont)|go:"GO:0035375"(zymogen binding)|go:"GO:0051603"(proteolysis involved in cellular protein catabolic process)|rcsb pdb:2FHG|rcsb pdb:2FHH|rcsb pdb:2JAY|rcsb pdb:3H6F|rcsb pdb:3H6I|rcsb pdb:3HF9|rcsb pdb:3HFA|rcsb pdb:3KRD|rcsb pdb:3MFE|rcsb pdb:3MI0|rcsb pdb:3MKA|rcsb pdb:5LZP|rcsb pdb:5THO|rcsb pdb:5TRG|rcsb pdb:5TRR|rcsb pdb:5TRS|rcsb pdb:5TRY|rcsb pdb:5TS0|rcsb pdb:6BGL|rcsb pdb:6BGO|rcsb pdb:6OCW|rcsb pdb:6OCZ|rcsb pdb:6ODE rcsb pdb:5LZP|refseq:WP_003906749.1|interpro:IPR029055|rcsb pdb:6BGL|rcsb pdb:6BGO|interpro:IPR001353(20S proteasome, A and B subunits)|rcsb pdb:3MKA|rcsb pdb:3MFE|rcsb pdb:2FHH|rcsb pdb:3MI0|refseq:NP_216625.1|rcsb pdb:3KRD|rcsb pdb:3H6I|rcsb pdb:2FHG|interpro:IPR022296|rcsb pdb:3H6F|rcsb pdb:3HF9|rcsb pdb:3HFA|interpro:IPR023332|rcsb pdb:5TRG|rcsb pdb:5TRR|rcsb pdb:5TRS|rcsb pdb:5TRY|rcsb pdb:5TS0|rcsb pdb:5THO|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005618"(cell wall)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0030682"(mitigation of host defenses by symbiont)|go:"GO:0051603"(proteolysis involved in cellular protein catabolic process)|rcsb pdb:6OCW|rcsb pdb:6OCZ|rcsb pdb:6ODE psi-mi:"MI:0465"(dip) crc64:3FC3FCD81231E129|comment:mint crc64:0356FED74869998A|comment:mint full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/06 2017/08/10 rogid:hQ8Eci/BIL/quaWNhklTdFRPHDI83332 rogid:x+ay7zDnb1yxK8fnu0bFdjkHoS883332 rigid:84Z0Wc2zy2k4ObYyHintX+1EhNs false his tag:c-c - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)