#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:O95631	uniprotkb:P43146	intact:EBI-2678626|uniprotkb:E9KL51|ensembl:ENSP00000173229	intact:EBI-1222919|ensembl:ENSP00000389140	psi-mi:net1_human(display_long)|uniprotkb:NTN1(gene name)|psi-mi:NTN1(display_short)|uniprotkb:NTN1L(gene name synonym)|uniprotkb:Epididymis tissue protein Li 131P(gene name synonym)	psi-mi:dcc_human(display_long)|uniprotkb:DCC(gene name)|psi-mi:DCC(display_short)|uniprotkb:Tumor suppressor protein DCC(gene name synonym)|uniprotkb:Colorectal cancer suppressor(gene name synonym)|uniprotkb:IGDCC1(gene name synonym)|uniprotkb:Immunoglobulin superfamily DCC subclass member 1(gene name synonym)	psi-mi:"MI:0892"(solid phase assay)	Paradisi et al. (2009)	pubmed:19721007|doi:10.1073/pnas.0901767106|imex:IM-15252	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15802270|imex:IM-15252-1|dip:DIP-185137E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004813.2|ensembl:ENSG00000065320(gene)|ensembl:ENST00000173229(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0006915"(apoptotic process)|go:"GO:0006930"(substrate-dependent cell migration, cell extension)|go:"GO:0007097"(nuclear migration)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009888"(tissue development)|go:"GO:0016358"(dendrite development)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030517"(negative regulation of axon extension)|go:"GO:0032488"(Cdc42 protein signal transduction)|go:"GO:0033564"(anterior/posterior axon guidance)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0051963"(regulation of synapse assembly)|go:"GO:0060603"(mammary gland duct morphogenesis)|go:"GO:0061643"(chemorepulsion of axon)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:2000147"(positive regulation of cell motility)|interpro:IPR001134(Netrin, C-terminal)|interpro:IPR002049(EGF-like, laminin)|interpro:IPR008211(Laminin, N-terminal)|interpro:IPR008979(Galactose-binding like)|interpro:IPR008993(TIMP-like, OB-fold)|interpro:IPR018933|rcsb pdb:4URT|rcsb pdb:6FKQ|rcsb pdb:7NDG|rcsb pdb:7NE0|rcsb pdb:7NE1|reactome:R-HSA-373752|reactome:R-HSA-376172|reactome:R-HSA-418885|reactome:R-HSA-418886|reactome:R-HSA-418890|reactome:R-HSA-428542|refseq:XP_006721658.1|dip:DIP-46273N	refseq:NP_005206.2|dip:DIP-38423N|ensembl:ENSG00000187323(gene)|ensembl:ENST00000442544(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005042"(netrin receptor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007409"(axonogenesis)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0021965"(spinal cord ventral commissure morphogenesis)|go:"GO:0030424"(axon)|go:"GO:0033563"(dorsal/ventral axon guidance)|go:"GO:0033564"(anterior/posterior axon guidance)|go:"GO:0048671"(negative regulation of collateral sprouting)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0099170"(postsynaptic modulation of chemical synaptic transmission)|go:"GO:1901214"(regulation of neuron death)|go:"GO:2000171"(negative regulation of dendrite development)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR010560(Neogenin, C-terminal)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR033012|interpro:IPR036116|interpro:IPR036179|rcsb pdb:2ED7|rcsb pdb:2ED8|rcsb pdb:2ED9|rcsb pdb:2EDB|rcsb pdb:2EDD|rcsb pdb:2EDE|rcsb pdb:3AU4|rcsb pdb:4URT|rcsb pdb:5X83|reactome:R-HSA-373752|reactome:R-HSA-376172|reactome:R-HSA-418885|reactome:R-HSA-418886|reactome:R-HSA-418889|reactome:R-HSA-418890|reactome:R-HSA-428542	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/06	2017/08/10	rogid:lDiYjrwbQf/qcr8gt7sbXMBkuMw9606	rogid:1Spe7wn0fsPMSm9kxF+FCKrtqqk9606	rigid:liprx2KD0oKguJc47pOKWaCLGvk	false	-	binding-associated region:726-814	-	-	psi-mi:"MI:0411"(enzyme linked immunosorbent assay)	psi-mi:"MI:0411"(enzyme linked immunosorbent assay)
uniprotkb:Q9HB63	uniprotkb:P43146	intact:EBI-743459|ensembl:ENSP00000340998|uniprotkb:Q658K9|uniprotkb:Q7L3F1|uniprotkb:Q7L9D6|uniprotkb:Q7Z5B6|uniprotkb:Q9BZP1|uniprotkb:Q9NT44|uniprotkb:Q9P133|uniprotkb:B2RNC2	intact:EBI-1222919|ensembl:ENSP00000389140	psi-mi:net4_human(display_long)|uniprotkb:Beta-netrin(gene name synonym)|uniprotkb:Hepar-derived netrin-like protein(gene name synonym)|uniprotkb:NTN4(gene name)|psi-mi:NTN4(display_short)	psi-mi:dcc_human(display_long)|uniprotkb:DCC(gene name)|psi-mi:DCC(display_short)|uniprotkb:Tumor suppressor protein DCC(gene name synonym)|uniprotkb:Colorectal cancer suppressor(gene name synonym)|uniprotkb:IGDCC1(gene name synonym)|uniprotkb:Immunoglobulin superfamily DCC subclass member 1(gene name synonym)	psi-mi:"MI:0892"(solid phase assay)	Paradisi et al. (2009)	pubmed:19721007|doi:10.1073/pnas.0901767106|imex:IM-15252	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15802289|imex:IM-15252-2|dip:DIP-185774E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR002049(EGF-like, laminin)|interpro:IPR008211(Laminin, N-terminal)|interpro:IPR008993(TIMP-like, OB-fold)|interpro:IPR018933|ensembl:ENSG00000074527(gene)|ensembl:ENST00000343702(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009888"(tissue development)|go:"GO:0016322"(neuron remodeling)|go:"GO:0016477"(cell migration)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0043237"(laminin-1 binding)|interpro:IPR035811|reactome:R-HSA-3000171|reactome:R-HSA-373752|go:"GO:0043256"(laminin complex)|go:"GO:0060668"(regulation of branching involved in salivary gland morphogenesis by extracellular matrix-epithelial cell signaling)|go:"GO:0070831"(basement membrane assembly)|interpro:IPR001134(Netrin, C-terminal)|refseq:NP_067052.2|refseq:NP_001316629.1|refseq:NP_001316630.1|refseq:NP_001316631.1|dip:DIP-46274N	refseq:NP_005206.2|dip:DIP-38423N|ensembl:ENSG00000187323(gene)|ensembl:ENST00000442544(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005042"(netrin receptor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007409"(axonogenesis)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0021965"(spinal cord ventral commissure morphogenesis)|go:"GO:0030424"(axon)|go:"GO:0033563"(dorsal/ventral axon guidance)|go:"GO:0033564"(anterior/posterior axon guidance)|go:"GO:0048671"(negative regulation of collateral sprouting)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0099170"(postsynaptic modulation of chemical synaptic transmission)|go:"GO:1901214"(regulation of neuron death)|go:"GO:2000171"(negative regulation of dendrite development)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR010560(Neogenin, C-terminal)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR033012|interpro:IPR036116|interpro:IPR036179|rcsb pdb:2ED7|rcsb pdb:2ED8|rcsb pdb:2ED9|rcsb pdb:2EDB|rcsb pdb:2EDD|rcsb pdb:2EDE|rcsb pdb:3AU4|rcsb pdb:4URT|rcsb pdb:5X83|reactome:R-HSA-373752|reactome:R-HSA-376172|reactome:R-HSA-418885|reactome:R-HSA-418886|reactome:R-HSA-418889|reactome:R-HSA-418890|reactome:R-HSA-428542	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/06	2017/08/10	rogid:Wiq3R27SFsSneLrCDSpL19glpxE9606	rogid:1Spe7wn0fsPMSm9kxF+FCKrtqqk9606	rigid:qJ8atVsYK1yJHrTAXj4cdXg1LWE	false	-	binding-associated region:726-814	-	-	psi-mi:"MI:0411"(enzyme linked immunosorbent assay)	psi-mi:"MI:0411"(enzyme linked immunosorbent assay)
uniprotkb:P43146	uniprotkb:P55211	intact:EBI-1222919|ensembl:ENSP00000389140	intact:EBI-516799|uniprotkb:O95348|uniprotkb:Q92852|uniprotkb:Q9BQ62|uniprotkb:Q9UEQ3|uniprotkb:Q9UIJ8|uniprotkb:Q53Y70|uniprotkb:Q5JRU9|uniprotkb:Q5UGI1|uniprotkb:B4E1A3|ensembl:ENSP00000330237	psi-mi:dcc_human(display_long)|uniprotkb:DCC(gene name)|psi-mi:DCC(display_short)|uniprotkb:Tumor suppressor protein DCC(gene name synonym)|uniprotkb:Colorectal cancer suppressor(gene name synonym)|uniprotkb:IGDCC1(gene name synonym)|uniprotkb:Immunoglobulin superfamily DCC subclass member 1(gene name synonym)	psi-mi:casp9_human(display_long)|uniprotkb:ICE-like apoptotic protease 6(gene name synonym)|uniprotkb:Apoptotic protease Mch-6(gene name synonym)|uniprotkb:Apoptotic protease-activating factor 3(gene name synonym)|uniprotkb:CASP9(gene name)|psi-mi:CASP9(display_short)|uniprotkb:MCH6(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Paradisi et al. (2009)	pubmed:19721007|doi:10.1073/pnas.0901767106|imex:IM-15252	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15802308|imex:IM-15252-3|dip:DIP-185773E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005206.2|dip:DIP-38423N|ensembl:ENSG00000187323(gene)|ensembl:ENST00000442544(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005042"(netrin receptor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007409"(axonogenesis)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0021965"(spinal cord ventral commissure morphogenesis)|go:"GO:0030424"(axon)|go:"GO:0033563"(dorsal/ventral axon guidance)|go:"GO:0033564"(anterior/posterior axon guidance)|go:"GO:0048671"(negative regulation of collateral sprouting)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0099170"(postsynaptic modulation of chemical synaptic transmission)|go:"GO:1901214"(regulation of neuron death)|go:"GO:2000171"(negative regulation of dendrite development)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR010560(Neogenin, C-terminal)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR033012|interpro:IPR036116|interpro:IPR036179|rcsb pdb:2ED7|rcsb pdb:2ED8|rcsb pdb:2ED9|rcsb pdb:2EDB|rcsb pdb:2EDD|rcsb pdb:2EDE|rcsb pdb:3AU4|rcsb pdb:4URT|rcsb pdb:5X83|reactome:R-HSA-373752|reactome:R-HSA-376172|reactome:R-HSA-418885|reactome:R-HSA-418886|reactome:R-HSA-418889|reactome:R-HSA-418890|reactome:R-HSA-428542	refseq:NP_001264983.1|refseq:NP_001220.2|refseq:NP_127463.2|refseq:XP_005246071.1|dip:DIP-27625N|ensembl:ENSG00000132906(gene)|ensembl:ENST00000333868(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0002931"(response to ischemia)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007568"(aging)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0008233"(peptidase activity)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0008635"(activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030220"(platelet formation)|go:"GO:0032025"(response to cobalt ion)|go:"GO:0032355"(response to estradiol)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034349"(glial cell apoptotic process)|go:"GO:0034644"(cellular response to UV)|go:"GO:0042770"(signal transduction in response to DNA damage)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043293"(apoptosome)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0046677"(response to antibiotic)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0071887"(leukocyte apoptotic process)|go:"GO:0097153"(cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0097199"(cysteine-type endopeptidase activity involved in apoptotic signaling pathway)|go:"GO:0097200"(cysteine-type endopeptidase activity involved in execution phase of apoptosis)|go:"GO:2001020"(regulation of response to DNA damage stimulus)|interpro:IPR001309(Peptidase C14, ICE, catalytic subunit p20)|interpro:IPR001315(Caspase Recruitment)|interpro:IPR002138(Peptidase C14, caspase non-catalytic subunit p10)|interpro:IPR002398(Peptidase C14, caspase precursor p45)|interpro:IPR011029(DEATH-like)|interpro:IPR015917(Peptidase C14, caspase precursor p45, core)|interpro:IPR016129(Peptidase C14, ICE, catalytic subunit p20, active site)|interpro:IPR029030|interpro:IPR033139|interpro:IPR033171|interpro:IPR042147|mint:P55211|rcsb pdb:1JXQ|rcsb pdb:1NW9|rcsb pdb:2AR9|rcsb pdb:3D9T|rcsb pdb:3V3K|rcsb pdb:3YGS|rcsb pdb:4RHW|rcsb pdb:5JUY|rcsb pdb:5WVC|rcsb pdb:5WVE|reactome:R-HSA-111458|reactome:R-HSA-111459|reactome:R-HSA-111463|reactome:R-HSA-111464|reactome:R-HSA-168638|reactome:R-HSA-198323|reactome:R-HSA-418889|reactome:R-HSA-5674400|reactome:R-HSA-9627069	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/06	2017/08/10	rogid:1Spe7wn0fsPMSm9kxF+FCKrtqqk9606	rogid:IYW59Vh17AEnXa6/wLpkIPNE0Bo9606	rigid:3gzBqD7VUZjKXEeVHX+tjfUxspM	false	myc tag:n-n	ha tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)