#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q9UBV2 uniprotkb:Q8IWF2 intact:EBI-358766|uniprotkb:Q6UWT6|uniprotkb:Q9P1T9|uniprotkb:Q9UHK7|ensembl:ENSP00000337053 intact:EBI-10763361|uniprotkb:B2RDI4|uniprotkb:Q8N378|uniprotkb:Q96BD1|uniprotkb:Q9H5L5|uniprotkb:Q9H6M8|ensembl:ENSP00000216187|ensembl:ENSP00000380400|ensembl:ENSP00000380401 psi-mi:se1l1_human(display_long)|uniprotkb:SEL1L(gene name)|psi-mi:SEL1L(display_short)|uniprotkb:TSA305(gene name synonym)|uniprotkb:UNQ128/PRO1063(orf name)|uniprotkb:Suppressor of lin-12-like protein 1(gene name synonym) psi-mi:fxrd2_human(display_long)|uniprotkb:Endoplasmic reticulum flavoprotein associated with degradation(gene name synonym)|uniprotkb:FOXRED2(gene name)|psi-mi:FOXRED2(display_short)|uniprotkb:ERFAD(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Riemer et al. (2009) pubmed:19706418|doi:10.1073/pnas.0900742106|imex:IM-14800 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15800241|imex:IM-14800-1|dip:DIP-104019E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001231913.1|refseq:NP_005056.3|ensembl:ENSG00000071537(gene)|ensembl:ENST00000336735(transcript)|go:"GO:0000836"(Hrd1p ubiquitin ligase complex)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0009306"(protein secretion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0036503"(ERAD pathway)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0050821"(protein stabilization)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR006597(Sel1-like)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013806(Kringle-like fold)|interpro:IPR036943|mint:Q9UBV2|reactome:R-HSA-1912420|reactome:R-HSA-382556|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|reactome:R-HSA-901032|dip:DIP-46259N refseq:NP_001095841.1|refseq:NP_079231.4|ensembl:ENSG00000100350(gene)|ensembl:ENST00000216187(transcript)|ensembl:ENST00000397223(transcript)|ensembl:ENST00000397224(transcript)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0050660"(flavin adenine dinucleotide binding)|interpro:IPR036188|dip:DIP-48946N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/06 2017/08/10 rogid:eufE+8nfcHK8CDl+AQ5G+3NtL+09606 rogid:rZ4tKHGgxYdUAaFjXW+4qTisPzs9606 rigid:Le41HLDEPcAtl4Yi3A6CJx3MMOY false - ha tag:c-c - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9UBV2 uniprotkb:Q8IWF2 intact:EBI-358766|uniprotkb:Q6UWT6|uniprotkb:Q9P1T9|uniprotkb:Q9UHK7|ensembl:ENSP00000337053 intact:EBI-10763361|uniprotkb:B2RDI4|uniprotkb:Q8N378|uniprotkb:Q96BD1|uniprotkb:Q9H5L5|uniprotkb:Q9H6M8|ensembl:ENSP00000216187|ensembl:ENSP00000380400|ensembl:ENSP00000380401 psi-mi:se1l1_human(display_long)|uniprotkb:SEL1L(gene name)|psi-mi:SEL1L(display_short)|uniprotkb:TSA305(gene name synonym)|uniprotkb:UNQ128/PRO1063(orf name)|uniprotkb:Suppressor of lin-12-like protein 1(gene name synonym) psi-mi:fxrd2_human(display_long)|uniprotkb:Endoplasmic reticulum flavoprotein associated with degradation(gene name synonym)|uniprotkb:FOXRED2(gene name)|psi-mi:FOXRED2(display_short)|uniprotkb:ERFAD(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Riemer et al. (2009) pubmed:19706418|doi:10.1073/pnas.0900742106|imex:IM-14800 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15800277|imex:IM-14800-3|dip:DIP-104019E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001231913.1|refseq:NP_005056.3|ensembl:ENSG00000071537(gene)|ensembl:ENST00000336735(transcript)|go:"GO:0000836"(Hrd1p ubiquitin ligase complex)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0009306"(protein secretion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0036503"(ERAD pathway)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0050821"(protein stabilization)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR006597(Sel1-like)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013806(Kringle-like fold)|interpro:IPR036943|mint:Q9UBV2|reactome:R-HSA-1912420|reactome:R-HSA-382556|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|reactome:R-HSA-901032|dip:DIP-46259N refseq:NP_001095841.1|refseq:NP_079231.4|ensembl:ENSG00000100350(gene)|ensembl:ENST00000216187(transcript)|ensembl:ENST00000397223(transcript)|ensembl:ENST00000397224(transcript)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0050660"(flavin adenine dinucleotide binding)|interpro:IPR036188|dip:DIP-48946N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/06 2017/08/10 rogid:eufE+8nfcHK8CDl+AQ5G+3NtL+09606 rogid:rZ4tKHGgxYdUAaFjXW+4qTisPzs9606 rigid:Le41HLDEPcAtl4Yi3A6CJx3MMOY false - ha tag:c-c - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8IWF2 uniprotkb:Q9UBV2 intact:EBI-10763361|uniprotkb:B2RDI4|uniprotkb:Q8N378|uniprotkb:Q96BD1|uniprotkb:Q9H5L5|uniprotkb:Q9H6M8|ensembl:ENSP00000216187|ensembl:ENSP00000380400|ensembl:ENSP00000380401 intact:EBI-358766|uniprotkb:Q6UWT6|uniprotkb:Q9P1T9|uniprotkb:Q9UHK7|ensembl:ENSP00000337053 psi-mi:fxrd2_human(display_long)|uniprotkb:Endoplasmic reticulum flavoprotein associated with degradation(gene name synonym)|uniprotkb:FOXRED2(gene name)|psi-mi:FOXRED2(display_short)|uniprotkb:ERFAD(gene name synonym) psi-mi:se1l1_human(display_long)|uniprotkb:SEL1L(gene name)|psi-mi:SEL1L(display_short)|uniprotkb:TSA305(gene name synonym)|uniprotkb:UNQ128/PRO1063(orf name)|uniprotkb:Suppressor of lin-12-like protein 1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Riemer et al. (2009) pubmed:19706418|doi:10.1073/pnas.0900742106|imex:IM-14800 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15800296|imex:IM-14800-4|dip:DIP-104019E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001095841.1|refseq:NP_079231.4|ensembl:ENSG00000100350(gene)|ensembl:ENST00000216187(transcript)|ensembl:ENST00000397223(transcript)|ensembl:ENST00000397224(transcript)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0050660"(flavin adenine dinucleotide binding)|interpro:IPR036188|dip:DIP-48946N refseq:NP_001231913.1|refseq:NP_005056.3|ensembl:ENSG00000071537(gene)|ensembl:ENST00000336735(transcript)|go:"GO:0000836"(Hrd1p ubiquitin ligase complex)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0009306"(protein secretion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0036503"(ERAD pathway)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0050821"(protein stabilization)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR006597(Sel1-like)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013806(Kringle-like fold)|interpro:IPR036943|mint:Q9UBV2|reactome:R-HSA-1912420|reactome:R-HSA-382556|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|reactome:R-HSA-901032|dip:DIP-46259N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/06 2017/08/10 rogid:rZ4tKHGgxYdUAaFjXW+4qTisPzs9606 rogid:eufE+8nfcHK8CDl+AQ5G+3NtL+09606 rigid:Le41HLDEPcAtl4Yi3A6CJx3MMOY false ha tag:c-c - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q13438 uniprotkb:Q8IWF2 intact:EBI-725454|intact:EBI-1174342|uniprotkb:A6NDD1|uniprotkb:A6NFR7|uniprotkb:A6NLB2|uniprotkb:A8K5Q9|uniprotkb:B4DPX1|uniprotkb:B4E1I6|uniprotkb:E7ENT8|uniprotkb:F8VUH2|uniprotkb:O00579|uniprotkb:Q6IBL2|uniprotkb:Q8IZ58|uniprotkb:Q9BW99|uniprotkb:B4DE28|ensembl:ENSP00000318165|uniprotkb:E7EW91|uniprotkb:G3XA88 intact:EBI-10763361|uniprotkb:B2RDI4|uniprotkb:Q8N378|uniprotkb:Q96BD1|uniprotkb:Q9H5L5|uniprotkb:Q9H6M8|ensembl:ENSP00000216187|ensembl:ENSP00000380400|ensembl:ENSP00000380401 psi-mi:os9_human(display_long)|uniprotkb:OS9(gene name)|psi-mi:OS9(display_short)|uniprotkb:Amplified in osteosarcoma 9(gene name synonym) psi-mi:fxrd2_human(display_long)|uniprotkb:Endoplasmic reticulum flavoprotein associated with degradation(gene name synonym)|uniprotkb:FOXRED2(gene name)|psi-mi:FOXRED2(display_short)|uniprotkb:ERFAD(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Riemer et al. (2009) pubmed:19706418|doi:10.1073/pnas.0900742106|imex:IM-14800 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15800315|imex:IM-14800-5|dip:DIP-104021E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006803.1|refseq:NP_001017956.1|refseq:NP_001017957.1|refseq:NP_001017958.1|refseq:NP_001248349.1|refseq:NP_001248350.1|refseq:NP_001248351.1|refseq:NP_001248352.1|ensembl:ENSG00000135506(gene)|ensembl:ENST00000315970(transcript)|go:"GO:0000836"(Hrd1p ubiquitin ligase complex)|go:"GO:0002020"(protease binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006605"(protein targeting)|go:"GO:0006621"(protein retention in ER lumen)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|interpro:IPR009011(Mannose-6-phosphate receptor, binding)|interpro:IPR012913(Glucosidase II beta subunit-like)|interpro:IPR044865|rcsb pdb:3AIH|reactome:R-HSA-382556|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|reactome:R-HSA-901032|dip:DIP-37493N refseq:NP_001095841.1|refseq:NP_079231.4|ensembl:ENSG00000100350(gene)|ensembl:ENST00000216187(transcript)|ensembl:ENST00000397223(transcript)|ensembl:ENST00000397224(transcript)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0050660"(flavin adenine dinucleotide binding)|interpro:IPR036188|dip:DIP-48946N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/06 2017/08/10 rogid:Ntc3geE7th+rBeIp0MxuUuu/28Y9606 rogid:rZ4tKHGgxYdUAaFjXW+4qTisPzs9606 rigid:LCxHpEePqqXtq7oa/wb5KpaN1Wg false - ha tag:c-c - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8IXB1 uniprotkb:Q8IWF2 intact:EBI-2949763|ensembl:ENSP00000264065|uniprotkb:Q53QT7|uniprotkb:Q6UWZ6|uniprotkb:Q96K44|uniprotkb:Q8NC82|uniprotkb:Q86T61|uniprotkb:Q9NSY6|uniprotkb:Q17RJ6|uniprotkb:Q8TD87|uniprotkb:Q96K54|uniprotkb:Q96K38|uniprotkb:Q4ZG06|uniprotkb:Q3B7W8 intact:EBI-10763361|uniprotkb:B2RDI4|uniprotkb:Q8N378|uniprotkb:Q96BD1|uniprotkb:Q9H5L5|uniprotkb:Q9H6M8|ensembl:ENSP00000216187|ensembl:ENSP00000380400|ensembl:ENSP00000380401 psi-mi:djc10_human(display_long)|uniprotkb:DNAJC10(gene name)|psi-mi:DNAJC10(display_short)|uniprotkb:ERDJ5(gene name synonym)|uniprotkb:Macrothioredoxin(gene name synonym)|uniprotkb:UNQ495/PRO1012(orf name)|uniprotkb:Endoplasmic reticulum DNA J domain-containing protein 5(gene name synonym) psi-mi:fxrd2_human(display_long)|uniprotkb:Endoplasmic reticulum flavoprotein associated with degradation(gene name synonym)|uniprotkb:FOXRED2(gene name)|psi-mi:FOXRED2(display_short)|uniprotkb:ERFAD(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Riemer et al. (2009) pubmed:19706418|doi:10.1073/pnas.0900742106|imex:IM-14800 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15800260|imex:IM-14800-2|dip:DIP-104020E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000077232(gene)|ensembl:ENST00000264065(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0015036"(disulfide oxidoreductase activity)|go:"GO:0016020"(membrane)|go:"GO:0016671"(oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0051087"(chaperone binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017937|interpro:IPR021170|interpro:IPR035673|interpro:IPR035674|interpro:IPR036249|interpro:IPR036869|mint:Q8IXB1|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|refseq:NP_061854.1|refseq:NP_001258510.1|dip:DIP-48947N refseq:NP_001095841.1|refseq:NP_079231.4|ensembl:ENSG00000100350(gene)|ensembl:ENST00000216187(transcript)|ensembl:ENST00000397223(transcript)|ensembl:ENST00000397224(transcript)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0050660"(flavin adenine dinucleotide binding)|interpro:IPR036188|dip:DIP-48946N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/06 2017/08/10 rogid:sD/pp49jws0LrBjwCxQmZqzfR9U9606 rogid:rZ4tKHGgxYdUAaFjXW+4qTisPzs9606 rigid:x1rEeob8tmPBYzfJZCwjLu2iiGQ false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8IXB1 uniprotkb:Q8IWF2 intact:EBI-2949763|ensembl:ENSP00000264065|uniprotkb:Q53QT7|uniprotkb:Q6UWZ6|uniprotkb:Q96K44|uniprotkb:Q8NC82|uniprotkb:Q86T61|uniprotkb:Q9NSY6|uniprotkb:Q17RJ6|uniprotkb:Q8TD87|uniprotkb:Q96K54|uniprotkb:Q96K38|uniprotkb:Q4ZG06|uniprotkb:Q3B7W8 intact:EBI-10763361|uniprotkb:B2RDI4|uniprotkb:Q8N378|uniprotkb:Q96BD1|uniprotkb:Q9H5L5|uniprotkb:Q9H6M8|ensembl:ENSP00000216187|ensembl:ENSP00000380400|ensembl:ENSP00000380401 psi-mi:djc10_human(display_long)|uniprotkb:DNAJC10(gene name)|psi-mi:DNAJC10(display_short)|uniprotkb:ERDJ5(gene name synonym)|uniprotkb:Macrothioredoxin(gene name synonym)|uniprotkb:UNQ495/PRO1012(orf name)|uniprotkb:Endoplasmic reticulum DNA J domain-containing protein 5(gene name synonym) psi-mi:fxrd2_human(display_long)|uniprotkb:Endoplasmic reticulum flavoprotein associated with degradation(gene name synonym)|uniprotkb:FOXRED2(gene name)|psi-mi:FOXRED2(display_short)|uniprotkb:ERFAD(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Riemer et al. (2009) pubmed:19706418|doi:10.1073/pnas.0900742106|imex:IM-14800 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15800334|imex:IM-14800-6|dip:DIP-104020E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000077232(gene)|ensembl:ENST00000264065(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0015036"(disulfide oxidoreductase activity)|go:"GO:0016020"(membrane)|go:"GO:0016671"(oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0051087"(chaperone binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017937|interpro:IPR021170|interpro:IPR035673|interpro:IPR035674|interpro:IPR036249|interpro:IPR036869|mint:Q8IXB1|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|refseq:NP_061854.1|refseq:NP_001258510.1|dip:DIP-48947N refseq:NP_001095841.1|refseq:NP_079231.4|ensembl:ENSG00000100350(gene)|ensembl:ENST00000216187(transcript)|ensembl:ENST00000397223(transcript)|ensembl:ENST00000397224(transcript)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0050660"(flavin adenine dinucleotide binding)|interpro:IPR036188|dip:DIP-48946N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/06 2017/08/10 rogid:sD/pp49jws0LrBjwCxQmZqzfR9U9606 rogid:rZ4tKHGgxYdUAaFjXW+4qTisPzs9606 rigid:x1rEeob8tmPBYzfJZCwjLu2iiGQ false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)