#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q8N335	uniprotkb:Q14524	intact:EBI-13644267|ensembl:ENSP00000282541|uniprotkb:A8K9U3|uniprotkb:Q14702|uniprotkb:Q9BRM5	intact:EBI-726858|uniprotkb:Q59H93|uniprotkb:E9PEF3|uniprotkb:A5H1P8|uniprotkb:A6N922|uniprotkb:A6N923|uniprotkb:B2RTU0|uniprotkb:Q75RX9|uniprotkb:Q75RY0|uniprotkb:Q86UR3|uniprotkb:Q8IZC9|uniprotkb:Q96J69|uniprotkb:E9PEK2|uniprotkb:E9PFW7|uniprotkb:E7ET19|intact:EBI-28981518|ensembl:ENSP00000328968	psi-mi:gpd1l_human(display_long)|uniprotkb:GPD1L(gene name)|psi-mi:GPD1L(display_short)|uniprotkb:KIAA0089(gene name synonym)	psi-mi:scn5a_human(display_long)|uniprotkb:Sodium channel protein type V subunit alpha(gene name synonym)|uniprotkb:Voltage-gated sodium channel subunit alpha Nav1.5(gene name synonym)|uniprotkb:Sodium channel protein cardiac muscle subunit alpha(gene name synonym)|uniprotkb:SCN5A(gene name)|psi-mi:SCN5A(display_short)|uniprotkb:hH1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Valdivia et al. (2009)	pubmed:19666841|imex:IM-25665	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-13644311|imex:IM-25665-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000152642(gene)|ensembl:ENST00000282541(transcript)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006734"(NADH metabolic process)|go:"GO:0009331"(glycerol-3-phosphate dehydrogenase complex)|go:"GO:0010765"(positive regulation of sodium ion transport)|go:"GO:0016616"(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019674"(NAD metabolic process)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0046168"(glycerol-3-phosphate catabolic process)|go:"GO:0051287"(NAD binding)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090038"(negative regulation of protein kinase C signaling)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|interpro:IPR006109(NAD-dependent glycerol-3-phosphate dehydrogenase, C-terminal)|interpro:IPR006168(NAD-dependent glycerol-3-phosphate dehydrogenase)|interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|interpro:IPR011128(NAD-dependent glycerol-3-phosphate dehydrogenase, N-terminal)|interpro:IPR013328(Dehydrogenase, multihelical)|interpro:IPR017751(NAD-dependent glycerol-3-phosphate dehydrogenase, eukaryotic)|interpro:IPR036291|rcsb pdb:2PLA|reactome:R-HSA-1483166|refseq:NP_055956.1	refseq:NP_000326.2|refseq:NP_001092874.1|refseq:NP_001092875.1|refseq:NP_001153632.1|refseq:NP_001153633.1|refseq:NP_932173.1|ensembl:ENSP00000328968|ensembl:ENST00000423572|ensembl:ENSP00000398266|ensembl:ENSG00000183873(gene)|ensembl:ENST00000333535(transcript)|go:"GO:0001518"(voltage-gated sodium channel complex)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003161"(cardiac conduction system development)|go:"GO:0003231"(cardiac ventricle development)|go:"GO:0003360"(brainstem development)|go:"GO:0005244"(voltage-gated ion channel activity)|go:"GO:0005248"(voltage-gated sodium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006814"(sodium ion transport)|go:"GO:0009986"(cell surface)|go:"GO:0010765"(positive regulation of sodium ion transport)|go:"GO:0014704"(intercalated disc)|go:"GO:0014894"(response to denervation involved in regulation of muscle adaptation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0017134"(fibroblast growth factor binding)|go:"GO:0019228"(neuronal action potential)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0030018"(Z disc)|go:"GO:0030315"(T-tubule)|go:"GO:0030506"(ankyrin binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0042383"(sarcolemma)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045760"(positive regulation of action potential)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051899"(membrane depolarization)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060371"(regulation of atrial cardiac muscle cell membrane depolarization)|go:"GO:0060372"(regulation of atrial cardiac muscle cell membrane repolarization)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086004"(regulation of cardiac muscle cell contraction)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086006"(voltage-gated sodium channel activity involved in cardiac muscle cell action potential)|go:"GO:0086010"(membrane depolarization during action potential)|go:"GO:0086012"(membrane depolarization during cardiac muscle cell action potential)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086015"(SA node cell action potential)|go:"GO:0086016"(AV node cell action potential)|go:"GO:0086045"(membrane depolarization during AV node cell action potential)|go:"GO:0086046"(membrane depolarization during SA node cell action potential)|go:"GO:0086047"(membrane depolarization during Purkinje myocyte cell action potential)|go:"GO:0086048"(membrane depolarization during bundle of His cell action potential)|go:"GO:0086060"(voltage-gated sodium channel activity involved in AV node cell action potential)|go:"GO:0086061"(voltage-gated sodium channel activity involved in bundle of His cell action potential)|go:"GO:0086062"(voltage-gated sodium channel activity involved in Purkinje myocyte action potential)|go:"GO:0086063"(voltage-gated sodium channel activity involved in SA node cell action potential)|go:"GO:0086067"(AV node cell to bundle of His cell communication)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098912"(membrane depolarization during atrial cardiac muscle cell action potential)|go:"GO:1902305"(regulation of sodium ion transmembrane transport)|interpro:IPR001696(Na+ channel)|interpro:IPR005821(Ion transport)|interpro:IPR008053(Na+ channel 5)|interpro:IPR010526(Sodium ion transport-associated)|interpro:IPR024583|interpro:IPR027359|interpro:IPR043203|interpro:IPR044564|rcsb pdb:2KBI|rcsb pdb:2L53|go:"GO:0086043"(bundle of His cell action potential)|rcsb pdb:4DCK|rcsb pdb:4DJC|rcsb pdb:4JQ0|rcsb pdb:4OVN|rcsb pdb:5DBR|rcsb pdb:6LQA|rcsb pdb:6MUD|rcsb pdb:7DTC|rcsb pdb:7L83|reactome:R-HSA-445095|reactome:R-HSA-5576892|dip:DIP-38416N|dip:DIP-46144N	-	comment:glu83lys and ala280val mutant constucts also interact	caution:This sequence has been withdrawn from Uniprot.	figure legend:5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/02/10	2017/02/10	rogid:ub8N5ZLWMXhTFvhAS6nKypG7ylw9606	rogid:WJ23sEfaxGTHEngY52K92JChA6U9606	rigid:Ij90ZgDYnjC1/krq23Ef4++s47c	false	glutathione s tranferase tag:n-n|mutation with no effect:83-83|mutation with no effect:280-280	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
chebi:"CHEBI:15978"	uniprotkb:Q8N335	intact:EBI-8874536|chebi:"CHEBI:10648"|chebi:"CHEBI:12843"|chebi:"CHEBI:12848"|chebi:"CHEBI:26705"|chebi:"CHEBI:42793"|chebi:"CHEBI:795270"	intact:EBI-13644267|ensembl:ENSP00000282541|uniprotkb:A8K9U3|uniprotkb:Q14702|uniprotkb:Q9BRM5	psi-mi:sn-glycerol 3-phosphate(display_short)|psi-mi:"CHEBI:15978"(display_long)|intact:"(R)-glycerol 1-phosphate"(synonym)|intact:"D-(glycerol 1-phosphate)"(synonym)|intact:Glycerol-3-phosphate(synonym)|intact:Glycerophosphoric acid(synonym)|intact:"L-(glycerol 3-phosphate)"(synonym)|intact:"phosphoric acid mono-((R)-2,3-dihydroxy-propyl) ester"(synonym)|intact:"Phosphorsaeure-mono-((R)-2,3-dihydroxy-propylester)"(synonym)|intact:sn-Glycerol 3-phosphate(synonym)|intact:SN-GLYCEROL-3-PHOSPHATE(synonym)|intact:sn-Gro-1-P(synonym)|intact:"(2R)-2,3-dihydroxypropyl dihydrogen phosphate"(iupac name)|intact:"sn-glycerol 3-(dihydrogen phosphate)"(iupac name)	psi-mi:gpd1l_human(display_long)|uniprotkb:GPD1L(gene name)|psi-mi:GPD1L(display_short)|uniprotkb:KIAA0089(gene name synonym)	psi-mi:"MI:0979"(oxidoreductase assay)	Valdivia et al. (2009)	pubmed:19666841|imex:IM-25665	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0945"(oxidoreductase activity electron transfer reaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-13920589|imex:IM-25665-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSG00000152642(gene)|ensembl:ENST00000282541(transcript)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006734"(NADH metabolic process)|go:"GO:0009331"(glycerol-3-phosphate dehydrogenase complex)|go:"GO:0010765"(positive regulation of sodium ion transport)|go:"GO:0016616"(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019674"(NAD metabolic process)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0046168"(glycerol-3-phosphate catabolic process)|go:"GO:0051287"(NAD binding)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090038"(negative regulation of protein kinase C signaling)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|interpro:IPR006109(NAD-dependent glycerol-3-phosphate dehydrogenase, C-terminal)|interpro:IPR006168(NAD-dependent glycerol-3-phosphate dehydrogenase)|interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|interpro:IPR011128(NAD-dependent glycerol-3-phosphate dehydrogenase, N-terminal)|interpro:IPR013328(Dehydrogenase, multihelical)|interpro:IPR017751(NAD-dependent glycerol-3-phosphate dehydrogenase, eukaryotic)|interpro:IPR036291|rcsb pdb:2PLA|reactome:R-HSA-1483166|refseq:NP_055956.1	-	inchi key:AWUCVROLDVIAJX-GSVOUGTGSA-N	comment:glu83lys and ala280val mutant constucts also interact	figure legend:Fig. 2A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/02/10	2017/02/23	-	rogid:ub8N5ZLWMXhTFvhAS6nKypG7ylw9606	-	false	-	glutathione s tranferase tag:n-n|mutation decreasing interaction rate:83-83|mutation disrupting interaction rate:280-280	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)