#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P43490	uniprotkb:P43490	intact:EBI-2829310|uniprotkb:A4D0Q9|uniprotkb:A4D0R0|uniprotkb:Q3KQV0|uniprotkb:Q8WW95|ensembl:ENSP00000222553|ensembl:ENSP00000390591|ensembl:ENSP00000506129|ensembl:ENSP00000506540	intact:EBI-2829310|uniprotkb:A4D0Q9|uniprotkb:A4D0R0|uniprotkb:Q3KQV0|uniprotkb:Q8WW95|ensembl:ENSP00000222553|ensembl:ENSP00000390591|ensembl:ENSP00000506129|ensembl:ENSP00000506540	psi-mi:nampt_human(display_long)|uniprotkb:NAMPT(gene name)|psi-mi:NAMPT(display_short)|uniprotkb:PBEF(gene name synonym)|uniprotkb:PBEF1(gene name synonym)|uniprotkb:Pre-B-cell colony-enhancing factor 1(gene name synonym)|uniprotkb:Visfatin(gene name synonym)	psi-mi:nampt_human(display_long)|uniprotkb:NAMPT(gene name)|psi-mi:NAMPT(display_short)|uniprotkb:PBEF(gene name synonym)|uniprotkb:PBEF1(gene name synonym)|uniprotkb:Pre-B-cell colony-enhancing factor 1(gene name synonym)|uniprotkb:Visfatin(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Burgos et al. (2009)	pubmed:19666527|doi:10.1073/pnas.0903898106|imex:IM-14788	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15797676|imex:IM-14788-1|dip:DIP-57237E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005737.1|rcsb pdb:6E68|rcsb pdb:6PEB|rcsb pdb:6TA0|rcsb pdb:6TA2|rcsb pdb:6TAC|reactome:R-HSA-1368108|reactome:R-HSA-197264|rcsb pdb:6B76|ensembl:ENSG00000105835(gene)|ensembl:ENST00000222553(transcript)|ensembl:ENST00000424768(transcript)|ensembl:ENST00000681255(transcript)|ensembl:ENST00000681491(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0001774"(microglial cell activation)|go:"GO:0004514"("nicotinate-nucleotide diphosphorylase (carboxylating) activity")|go:"GO:0005125"(cytokine activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007565"(female pregnancy)|go:"GO:0007568"(aging)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0014916"(regulation of lung blood pressure)|go:"GO:0016607"(nuclear speck)|go:"GO:0030054"(cell junction)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0034356"(NAD biosynthesis via nicotinamide riboside salvage pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047280"(nicotinamide phosphoribosyltransferase activity)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0051770"(positive regulation of nitric-oxide synthase biosynthetic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070997"(neuron death)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0090650"(cellular response to oxygen-glucose deprivation)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1905377"(response to D-galactose)|go:"GO:2000773"(negative regulation of cellular senescence)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR016471(Nicotinamide phosphoribosyl transferase)|interpro:IPR036068|interpro:IPR041525|interpro:IPR041529|mint:P43490|rcsb pdb:2E5B|rcsb pdb:2E5C|rcsb pdb:2E5D|rcsb pdb:2GVG|rcsb pdb:2GVJ|rcsb pdb:3DGR|rcsb pdb:3DHD|rcsb pdb:3DHF|rcsb pdb:3DKJ|rcsb pdb:3DKL|rcsb pdb:4JNM|rcsb pdb:4JR5|rcsb pdb:4KFN|rcsb pdb:4KFO|rcsb pdb:4KFP|rcsb pdb:4L4L|rcsb pdb:4L4M|rcsb pdb:4LTS|rcsb pdb:4LV9|rcsb pdb:4LVA|rcsb pdb:4LVB|rcsb pdb:4LVD|rcsb pdb:4LVF|rcsb pdb:4LVG|rcsb pdb:4LWW|rcsb pdb:4M6P|rcsb pdb:4M6Q|rcsb pdb:4N9B|rcsb pdb:4N9C|rcsb pdb:4N9D|rcsb pdb:4N9E|rcsb pdb:4O0Z|rcsb pdb:4O10|rcsb pdb:4O12|rcsb pdb:4O13|rcsb pdb:4O14|rcsb pdb:4O15|rcsb pdb:4O16|rcsb pdb:4O17|rcsb pdb:4O18|rcsb pdb:4O19|rcsb pdb:4O1A|rcsb pdb:4O1B|rcsb pdb:4O1C|rcsb pdb:4O1D|rcsb pdb:4O28|rcsb pdb:4WQ6|rcsb pdb:5KIT|rcsb pdb:5LX3|rcsb pdb:5LX5|rcsb pdb:5NSD|rcsb pdb:5U2M|rcsb pdb:5U2N|rcsb pdb:5UPE|rcsb pdb:5UPF|rcsb pdb:5WI0|rcsb pdb:5WI1|rcsb pdb:6ATB|rcsb pdb:6AZJ|rcsb pdb:6B75|refseq:XP_005250157.1|dip:DIP-29218N	refseq:NP_005737.1|rcsb pdb:6E68|rcsb pdb:6PEB|rcsb pdb:6TA0|rcsb pdb:6TA2|rcsb pdb:6TAC|reactome:R-HSA-1368108|reactome:R-HSA-197264|rcsb pdb:6B76|ensembl:ENSG00000105835(gene)|ensembl:ENST00000222553(transcript)|ensembl:ENST00000424768(transcript)|ensembl:ENST00000681255(transcript)|ensembl:ENST00000681491(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0001774"(microglial cell activation)|go:"GO:0004514"("nicotinate-nucleotide diphosphorylase (carboxylating) activity")|go:"GO:0005125"(cytokine activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007565"(female pregnancy)|go:"GO:0007568"(aging)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0014916"(regulation of lung blood pressure)|go:"GO:0016607"(nuclear speck)|go:"GO:0030054"(cell junction)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0034356"(NAD biosynthesis via nicotinamide riboside salvage pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047280"(nicotinamide phosphoribosyltransferase activity)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0051770"(positive regulation of nitric-oxide synthase biosynthetic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070997"(neuron death)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0090650"(cellular response to oxygen-glucose deprivation)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1905377"(response to D-galactose)|go:"GO:2000773"(negative regulation of cellular senescence)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR016471(Nicotinamide phosphoribosyl transferase)|interpro:IPR036068|interpro:IPR041525|interpro:IPR041529|mint:P43490|rcsb pdb:2E5B|rcsb pdb:2E5C|rcsb pdb:2E5D|rcsb pdb:2GVG|rcsb pdb:2GVJ|rcsb pdb:3DGR|rcsb pdb:3DHD|rcsb pdb:3DHF|rcsb pdb:3DKJ|rcsb pdb:3DKL|rcsb pdb:4JNM|rcsb pdb:4JR5|rcsb pdb:4KFN|rcsb pdb:4KFO|rcsb pdb:4KFP|rcsb pdb:4L4L|rcsb pdb:4L4M|rcsb pdb:4LTS|rcsb pdb:4LV9|rcsb pdb:4LVA|rcsb pdb:4LVB|rcsb pdb:4LVD|rcsb pdb:4LVF|rcsb pdb:4LVG|rcsb pdb:4LWW|rcsb pdb:4M6P|rcsb pdb:4M6Q|rcsb pdb:4N9B|rcsb pdb:4N9C|rcsb pdb:4N9D|rcsb pdb:4N9E|rcsb pdb:4O0Z|rcsb pdb:4O10|rcsb pdb:4O12|rcsb pdb:4O13|rcsb pdb:4O14|rcsb pdb:4O15|rcsb pdb:4O16|rcsb pdb:4O17|rcsb pdb:4O18|rcsb pdb:4O19|rcsb pdb:4O1A|rcsb pdb:4O1B|rcsb pdb:4O1C|rcsb pdb:4O1D|rcsb pdb:4O28|rcsb pdb:4WQ6|rcsb pdb:5KIT|rcsb pdb:5LX3|rcsb pdb:5LX5|rcsb pdb:5NSD|rcsb pdb:5U2M|rcsb pdb:5U2N|rcsb pdb:5UPE|rcsb pdb:5UPF|rcsb pdb:5WI0|rcsb pdb:5WI1|rcsb pdb:6ATB|rcsb pdb:6AZJ|rcsb pdb:6B75|refseq:XP_005250157.1|dip:DIP-29218N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:562(ecolx)|taxid:562(Escherichia coli)	-	2017/08/06	2017/08/10	rogid:EHLw18wP4t8gP0u8c6Nv/zOctiM9606	rogid:EHLw18wP4t8gP0u8c6Nv/zOctiM9606	rigid:iwLlty3WspjMxwUPF/OJdBuix/g	false	-	-	-	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P43490	uniprotkb:P43490	intact:EBI-2829310|uniprotkb:A4D0Q9|uniprotkb:A4D0R0|uniprotkb:Q3KQV0|uniprotkb:Q8WW95|ensembl:ENSP00000222553|ensembl:ENSP00000390591|ensembl:ENSP00000506129|ensembl:ENSP00000506540	intact:EBI-2829310|uniprotkb:A4D0Q9|uniprotkb:A4D0R0|uniprotkb:Q3KQV0|uniprotkb:Q8WW95|ensembl:ENSP00000222553|ensembl:ENSP00000390591|ensembl:ENSP00000506129|ensembl:ENSP00000506540	psi-mi:nampt_human(display_long)|uniprotkb:NAMPT(gene name)|psi-mi:NAMPT(display_short)|uniprotkb:PBEF(gene name synonym)|uniprotkb:PBEF1(gene name synonym)|uniprotkb:Pre-B-cell colony-enhancing factor 1(gene name synonym)|uniprotkb:Visfatin(gene name synonym)	psi-mi:nampt_human(display_long)|uniprotkb:NAMPT(gene name)|psi-mi:NAMPT(display_short)|uniprotkb:PBEF(gene name synonym)|uniprotkb:PBEF1(gene name synonym)|uniprotkb:Pre-B-cell colony-enhancing factor 1(gene name synonym)|uniprotkb:Visfatin(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Burgos et al. (2009)	pubmed:19666527|doi:10.1073/pnas.0903898106|imex:IM-14788	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15797697|imex:IM-14788-2|dip:DIP-57237E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005737.1|rcsb pdb:6E68|rcsb pdb:6PEB|rcsb pdb:6TA0|rcsb pdb:6TA2|rcsb pdb:6TAC|reactome:R-HSA-1368108|reactome:R-HSA-197264|rcsb pdb:6B76|ensembl:ENSG00000105835(gene)|ensembl:ENST00000222553(transcript)|ensembl:ENST00000424768(transcript)|ensembl:ENST00000681255(transcript)|ensembl:ENST00000681491(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0001774"(microglial cell activation)|go:"GO:0004514"("nicotinate-nucleotide diphosphorylase (carboxylating) activity")|go:"GO:0005125"(cytokine activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007565"(female pregnancy)|go:"GO:0007568"(aging)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0014916"(regulation of lung blood pressure)|go:"GO:0016607"(nuclear speck)|go:"GO:0030054"(cell junction)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0034356"(NAD biosynthesis via nicotinamide riboside salvage pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047280"(nicotinamide phosphoribosyltransferase activity)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0051770"(positive regulation of nitric-oxide synthase biosynthetic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070997"(neuron death)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0090650"(cellular response to oxygen-glucose deprivation)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1905377"(response to D-galactose)|go:"GO:2000773"(negative regulation of cellular senescence)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR016471(Nicotinamide phosphoribosyl transferase)|interpro:IPR036068|interpro:IPR041525|interpro:IPR041529|mint:P43490|rcsb pdb:2E5B|rcsb pdb:2E5C|rcsb pdb:2E5D|rcsb pdb:2GVG|rcsb pdb:2GVJ|rcsb pdb:3DGR|rcsb pdb:3DHD|rcsb pdb:3DHF|rcsb pdb:3DKJ|rcsb pdb:3DKL|rcsb pdb:4JNM|rcsb pdb:4JR5|rcsb pdb:4KFN|rcsb pdb:4KFO|rcsb pdb:4KFP|rcsb pdb:4L4L|rcsb pdb:4L4M|rcsb pdb:4LTS|rcsb pdb:4LV9|rcsb pdb:4LVA|rcsb pdb:4LVB|rcsb pdb:4LVD|rcsb pdb:4LVF|rcsb pdb:4LVG|rcsb pdb:4LWW|rcsb pdb:4M6P|rcsb pdb:4M6Q|rcsb pdb:4N9B|rcsb pdb:4N9C|rcsb pdb:4N9D|rcsb pdb:4N9E|rcsb pdb:4O0Z|rcsb pdb:4O10|rcsb pdb:4O12|rcsb pdb:4O13|rcsb pdb:4O14|rcsb pdb:4O15|rcsb pdb:4O16|rcsb pdb:4O17|rcsb pdb:4O18|rcsb pdb:4O19|rcsb pdb:4O1A|rcsb pdb:4O1B|rcsb pdb:4O1C|rcsb pdb:4O1D|rcsb pdb:4O28|rcsb pdb:4WQ6|rcsb pdb:5KIT|rcsb pdb:5LX3|rcsb pdb:5LX5|rcsb pdb:5NSD|rcsb pdb:5U2M|rcsb pdb:5U2N|rcsb pdb:5UPE|rcsb pdb:5UPF|rcsb pdb:5WI0|rcsb pdb:5WI1|rcsb pdb:6ATB|rcsb pdb:6AZJ|rcsb pdb:6B75|refseq:XP_005250157.1|dip:DIP-29218N	refseq:NP_005737.1|rcsb pdb:6E68|rcsb pdb:6PEB|rcsb pdb:6TA0|rcsb pdb:6TA2|rcsb pdb:6TAC|reactome:R-HSA-1368108|reactome:R-HSA-197264|rcsb pdb:6B76|ensembl:ENSG00000105835(gene)|ensembl:ENST00000222553(transcript)|ensembl:ENST00000424768(transcript)|ensembl:ENST00000681255(transcript)|ensembl:ENST00000681491(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0001774"(microglial cell activation)|go:"GO:0004514"("nicotinate-nucleotide diphosphorylase (carboxylating) activity")|go:"GO:0005125"(cytokine activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007565"(female pregnancy)|go:"GO:0007568"(aging)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0014916"(regulation of lung blood pressure)|go:"GO:0016607"(nuclear speck)|go:"GO:0030054"(cell junction)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0034356"(NAD biosynthesis via nicotinamide riboside salvage pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047280"(nicotinamide phosphoribosyltransferase activity)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0051770"(positive regulation of nitric-oxide synthase biosynthetic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070997"(neuron death)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0090650"(cellular response to oxygen-glucose deprivation)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1905377"(response to D-galactose)|go:"GO:2000773"(negative regulation of cellular senescence)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR016471(Nicotinamide phosphoribosyl transferase)|interpro:IPR036068|interpro:IPR041525|interpro:IPR041529|mint:P43490|rcsb pdb:2E5B|rcsb pdb:2E5C|rcsb pdb:2E5D|rcsb pdb:2GVG|rcsb pdb:2GVJ|rcsb pdb:3DGR|rcsb pdb:3DHD|rcsb pdb:3DHF|rcsb pdb:3DKJ|rcsb pdb:3DKL|rcsb pdb:4JNM|rcsb pdb:4JR5|rcsb pdb:4KFN|rcsb pdb:4KFO|rcsb pdb:4KFP|rcsb pdb:4L4L|rcsb pdb:4L4M|rcsb pdb:4LTS|rcsb pdb:4LV9|rcsb pdb:4LVA|rcsb pdb:4LVB|rcsb pdb:4LVD|rcsb pdb:4LVF|rcsb pdb:4LVG|rcsb pdb:4LWW|rcsb pdb:4M6P|rcsb pdb:4M6Q|rcsb pdb:4N9B|rcsb pdb:4N9C|rcsb pdb:4N9D|rcsb pdb:4N9E|rcsb pdb:4O0Z|rcsb pdb:4O10|rcsb pdb:4O12|rcsb pdb:4O13|rcsb pdb:4O14|rcsb pdb:4O15|rcsb pdb:4O16|rcsb pdb:4O17|rcsb pdb:4O18|rcsb pdb:4O19|rcsb pdb:4O1A|rcsb pdb:4O1B|rcsb pdb:4O1C|rcsb pdb:4O1D|rcsb pdb:4O28|rcsb pdb:4WQ6|rcsb pdb:5KIT|rcsb pdb:5LX3|rcsb pdb:5LX5|rcsb pdb:5NSD|rcsb pdb:5U2M|rcsb pdb:5U2N|rcsb pdb:5UPE|rcsb pdb:5UPF|rcsb pdb:5WI0|rcsb pdb:5WI1|rcsb pdb:6ATB|rcsb pdb:6AZJ|rcsb pdb:6B75|refseq:XP_005250157.1|dip:DIP-29218N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:562(ecolx)|taxid:562(Escherichia coli)	-	2017/08/06	2017/08/10	rogid:EHLw18wP4t8gP0u8c6Nv/zOctiM9606	rogid:EHLw18wP4t8gP0u8c6Nv/zOctiM9606	rigid:iwLlty3WspjMxwUPF/OJdBuix/g	false	-	-	-	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)