#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q00711 uniprotkb:Q08230 intact:EBI-5851|ensemblfungi:YKL148C|uniprotkb:D6VX49 intact:EBI-15795447|ensemblfungi:YOL071W|uniprotkb:D6W1Z6 psi-mi:sdha_yeast(display_long)|uniprotkb:SDH1(gene name)|psi-mi:SDH1(display_short)|uniprotkb:SDHA(gene name synonym)|uniprotkb:YKL148C(locus name)|uniprotkb:YKL602(orf name)|uniprotkb:Flavoprotein subunit of complex II(gene name synonym) psi-mi:sdhf2_yeast(display_long)|uniprotkb:SDH5(gene name)|psi-mi:SDH5(display_short)|uniprotkb:EMI5(gene name synonym)|uniprotkb:YOL071W(locus name) psi-mi:"MI:0676"(tandem affinity purification) Hao et al. (2009) pubmed:19628817|doi:10.1126/science.1175689|imex:IM-24814 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15795467|imex:IM-24814-1|dip:DIP-199786E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0009055"(electron transfer activity)|go:"GO:0031966"(mitochondrial membrane)|ensemblfungi:YKL148C(gene)|ensemblfungi:YKL148C_mRNA(transcript)|go:"GO:0000104"(succinate dehydrogenase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005749"("mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)")|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006121"(mitochondrial electron transport, succinate to ubiquinone)|go:"GO:0008177"("succinate dehydrogenase (ubiquinone) activity")|reactome:R-SCE-71403|refseq:NP_012774.1|sgd:S000001631|dip:DIP-5853N|go:"GO:0045333"(cellular respiration)|go:"GO:0050660"(flavin adenine dinucleotide binding)|interpro:IPR003952(Fumarate reductase/succinate dehydrogenase, FAD-binding site)|interpro:IPR003953(Fumarate reductase/succinate dehydrogenase flavoprotein, N-terminal)|interpro:IPR011281(Succinate dehydrogenase, flavoprotein subunit)|interpro:IPR014006(Succinate dehydrogenase or fumarate reductase, flavoprotein subunit)|interpro:IPR015939(Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal)|interpro:IPR027477|interpro:IPR036188|interpro:IPR037099|rcsb pdb:1ORZ|rcsb pdb:1PB4 ensemblfungi:YOL071W(gene)|ensemblfungi:YOL071W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006121"(mitochondrial electron transport, succinate to ubiquinone)|go:"GO:0017013"(protein flavinylation)|go:"GO:0018293"(protein-FAD linkage)|go:"GO:0030437"(ascospore formation)|go:"GO:0034553"(mitochondrial respiratory chain complex II assembly)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR005631(Protein of unknown function DUF339)|interpro:IPR028882|interpro:IPR036714|rcsb pdb:2LM4|refseq:NP_014570.1|sgd:S000005432|dip:DIP-61727N psi-mi:"MI:0465"(dip) crc64:A657E440B8ED58E2 crc64:8CDF8E943D46A12D full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/06 2017/08/10 rogid:EQ2NFEjW4fXnH8bzfRi60S6oBJk559292 rogid:t7EH/fBwQ0fF02a75Wgms7OtoTM559292 rigid:U2yGSDsWPJni3JX6wKXr45lRYCg false - tandem tag:c-c - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P31040 uniprotkb:Q9NX18 intact:EBI-1057265|uniprotkb:Q16395|uniprotkb:Q9UMY5|uniprotkb:B4DJ60|uniprotkb:E9PBJ5|uniprotkb:Q59GW8|uniprotkb:Q8IW48|uniprotkb:A8K5J6|ensembl:ENSP00000264932 intact:EBI-713250|ensembl:ENSP00000301761 psi-mi:sdha_human(display_long)|uniprotkb:SDHA(gene name)|psi-mi:SDHA(display_short)|uniprotkb:SDH2(gene name synonym)|uniprotkb:SDHF(gene name synonym)|uniprotkb:Flavoprotein subunit of complex II(gene name synonym) psi-mi:sdhf2_human(display_long)|uniprotkb:SDHAF2(gene name)|psi-mi:SDHAF2(display_short)|uniprotkb:C11orf79(gene name synonym)|uniprotkb:SDH5(gene name synonym)|uniprotkb:PGL2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Hao et al. (2009) pubmed:19628817|doi:10.1126/science.1175689|imex:IM-24814 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15795486|imex:IM-24814-2|dip:DIP-199787E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001281261.1|refseq:NP_004159.2|ensembl:ENSG00000073578(gene)|ensembl:ENST00000264932(transcript)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005749"("mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)")|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006105"(succinate metabolic process)|go:"GO:0006121"(mitochondrial electron transport, succinate to ubiquinone)|go:"GO:0007399"(nervous system development)|go:"GO:0008177"("succinate dehydrogenase (ubiquinone) activity")|go:"GO:0009055"(electron transfer activity)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0050660"(flavin adenine dinucleotide binding)|interpro:IPR003952(Fumarate reductase/succinate dehydrogenase, FAD-binding site)|interpro:IPR003953(Fumarate reductase/succinate dehydrogenase flavoprotein, N-terminal)|interpro:IPR011281(Succinate dehydrogenase, flavoprotein subunit)|interpro:IPR014006(Succinate dehydrogenase or fumarate reductase, flavoprotein subunit)|interpro:IPR015939(Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal)|interpro:IPR027477|interpro:IPR036188|interpro:IPR037099|rcsb pdb:6VAX|reactome:R-HSA-611105|reactome:R-HSA-71403|dip:DIP-45851N ensembl:ENSG00000167985(gene)|ensembl:ENST00000301761(transcript)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006121"(mitochondrial electron transport, succinate to ubiquinone)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0018293"(protein-FAD linkage)|go:"GO:0034553"(mitochondrial respiratory chain complex II assembly)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR005631(Protein of unknown function DUF339)|interpro:IPR028882|interpro:IPR036714|rcsb pdb:6VAX|refseq:NP_060311.1|dip:DIP-61728N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/06 2017/08/10 rogid:NfhgIzmcsvfPG1BP7tHcna+jTIY9606 rogid:XMtlhlPmPXH4Mk8zjET4JYvzwBo9606 rigid:Nkp//H4R2Am+UvhnGH3y0eoVS/c false - mutation disrupting interaction strength:78-78|myc tag:c-c - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)