#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:O15116 uniprotkb:Q9Y333 intact:EBI-347619|uniprotkb:B2R5E6|ensembl:ENSP00000310596 intact:EBI-347416|uniprotkb:Q6FGG1|ensembl:ENSP00000414006|ensembl:ENSP00000414634|ensembl:ENSP00000406280|ensembl:ENSP00000364813|ensembl:ENSP00000372883|ensembl:ENSP00000403345 psi-mi:lsm1_human(display_long)|uniprotkb:LSM1(gene name)|psi-mi:LSM1(display_short)|uniprotkb:CASM(gene name synonym)|uniprotkb:Cancer-associated Sm-like(gene name synonym)|uniprotkb:Small nuclear ribonuclear CaSm(gene name synonym) psi-mi:lsm2_human(display_long)|uniprotkb:LSM2(gene name)|psi-mi:LSM2(display_short)|uniprotkb:C6orf28(gene name synonym)|uniprotkb:G7B(gene name synonym)|uniprotkb:snRNP core Sm-like protein Sm-x5(gene name synonym)|uniprotkb:Small nuclear ribonuclear protein D homolog(gene name synonym)|uniprotkb:Protein G7b(gene name synonym) psi-mi:"MI:0226"(ion exchange chromatography) Scheller et al. (2009) pubmed:19628699|doi:10.1073/pnas.0906413106|imex:IM-14991 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15795343|imex:IM-14991-1|dip:DIP-185534E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055277.1|dip:DIP-31130N|ensembl:ENSG00000175324(gene)|ensembl:ENST00000311351(transcript)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000375"(RNA splicing, via transesterification reactions)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016070"(RNA metabolic process)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0071044"(histone mRNA catabolic process)|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:1990726"(Lsm1-7-Pat1 complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR034104|interpro:IPR044642|reactome:R-HSA-430039|go:"GO:0000932"(P-body) refseq:NP_067000.1|ensembl:ENST00000375661(transcript)|ensembl:ENST00000383391(transcript)|ensembl:ENST00000424975(transcript)|ensembl:ENST00000432122(transcript)|ensembl:ENST00000434125(transcript)|ensembl:ENST00000455705(transcript)|go:"GO:0000244"(spliceosomal tri-snRNP complex assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005688"(U6 snRNP)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0120115"(Lsm2-8 complex)|go:"GO:1990726"(Lsm1-7-Pat1 complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR016654(U6 snRNA-associated Sm-like protein LSm2)|mint:Q9Y333|rcsb pdb:3JCR|rcsb pdb:5O9Z|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:7ABG|reactome:R-HSA-430039|reactome:R-HSA-72163|reactome:R-HSA-72165|ensembl:ENSG00000172850(gene)|ensembl:ENSG00000204392(gene)|ensembl:ENSG00000224979(gene)|ensembl:ENSG00000225998(gene)|ensembl:ENSG00000231502(gene)|ensembl:ENSG00000236826(gene)|dip:DIP-31139N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/06 2017/08/10 rogid:4ZjCoUTZoEAWqp5wvQDTcTr4gs49606 rogid:lReyYTJxC/WlYg/ekKaqZiNNdVM9606 rigid:NM27m+uiRA+tscx/tl1b2MNgNAc false - - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:O15116 uniprotkb:P62310 intact:EBI-347619|uniprotkb:B2R5E6|ensembl:ENSP00000310596 intact:EBI-348239|ensembl:ENSP00000302160|uniprotkb:Q9Y4Z1|uniprotkb:Q6IAH0 psi-mi:lsm1_human(display_long)|uniprotkb:LSM1(gene name)|psi-mi:LSM1(display_short)|uniprotkb:CASM(gene name synonym)|uniprotkb:Cancer-associated Sm-like(gene name synonym)|uniprotkb:Small nuclear ribonuclear CaSm(gene name synonym) psi-mi:lsm3_human(display_long)|uniprotkb:MDS017(orf name)|uniprotkb:LSM3(gene name)|psi-mi:LSM3(display_short) psi-mi:"MI:0226"(ion exchange chromatography) Scheller et al. (2009) pubmed:19628699|doi:10.1073/pnas.0906413106|imex:IM-14991 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15795343|imex:IM-14991-1|dip:DIP-185534E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055277.1|dip:DIP-31130N|ensembl:ENSG00000175324(gene)|ensembl:ENST00000311351(transcript)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000375"(RNA splicing, via transesterification reactions)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016070"(RNA metabolic process)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0071044"(histone mRNA catabolic process)|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:1990726"(Lsm1-7-Pat1 complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR034104|interpro:IPR044642|reactome:R-HSA-430039|go:"GO:0000932"(P-body) ensembl:ENSG00000170860(gene)|ensembl:ENST00000306024(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000932"(P-body)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005688"(U6 snRNP)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0030629"(U6 snRNA 3'-end binding)|go:"GO:0033962"(P-body assembly)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0120115"(Lsm2-8 complex)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:1990726"(Lsm1-7-Pat1 complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR034105|interpro:IPR040002|mint:P62310|rcsb pdb:3JCR|rcsb pdb:5O9Z|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:7ABG|reactome:R-HSA-430039|reactome:R-HSA-72163|refseq:NP_055278.1|dip:DIP-31218N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/06 2017/08/10 rogid:4ZjCoUTZoEAWqp5wvQDTcTr4gs49606 rogid:+OnRI9eJcsd1xJe+cUCP7Y/9tt09606 rigid:NM27m+uiRA+tscx/tl1b2MNgNAc false - - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:O15116 uniprotkb:Q9Y4Z0 intact:EBI-347619|uniprotkb:B2R5E6|ensembl:ENSP00000310596 intact:EBI-372521|ensembl:ENSP00000469468 psi-mi:lsm1_human(display_long)|uniprotkb:LSM1(gene name)|psi-mi:LSM1(display_short)|uniprotkb:CASM(gene name synonym)|uniprotkb:Cancer-associated Sm-like(gene name synonym)|uniprotkb:Small nuclear ribonuclear CaSm(gene name synonym) psi-mi:lsm4_human(display_long)|uniprotkb:Glycine-rich protein(gene name synonym)|uniprotkb:LSM4(gene name)|psi-mi:LSM4(display_short) psi-mi:"MI:0226"(ion exchange chromatography) Scheller et al. (2009) pubmed:19628699|doi:10.1073/pnas.0906413106|imex:IM-14991 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15795343|imex:IM-14991-1|dip:DIP-185534E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055277.1|dip:DIP-31130N|ensembl:ENSG00000175324(gene)|ensembl:ENST00000311351(transcript)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000375"(RNA splicing, via transesterification reactions)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016070"(RNA metabolic process)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0071044"(histone mRNA catabolic process)|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:1990726"(Lsm1-7-Pat1 complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR034104|interpro:IPR044642|reactome:R-HSA-430039|go:"GO:0000932"(P-body) refseq:NP_036453.1|ensembl:ENSG00000130520(gene)|ensembl:ENST00000593829(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000932"(P-body)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005688"(U6 snRNP)|go:"GO:0005829"(cytosol)|go:"GO:0008380"(RNA splicing)|go:"GO:0016020"(membrane)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033962"(P-body assembly)|go:"GO:0042731"(PH domain binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0043005"(neuron projection)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0097526"(spliceosomal tri-snRNP complex)|go:"GO:0120115"(Lsm2-8 complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR027141|interpro:IPR034101|rcsb pdb:3JCR|rcsb pdb:5O9Z|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:7ABG|reactome:R-HSA-430039|reactome:R-HSA-72163|dip:DIP-31209N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/06 2017/08/10 rogid:4ZjCoUTZoEAWqp5wvQDTcTr4gs49606 rogid:FlaQveuBbixGvfX47pCm26xscT09606 rigid:NM27m+uiRA+tscx/tl1b2MNgNAc false - - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:O15116 uniprotkb:Q9Y4Y9 intact:EBI-347619|uniprotkb:B2R5E6|ensembl:ENSP00000310596 intact:EBI-373007|ensembl:ENSP00000410758 psi-mi:lsm1_human(display_long)|uniprotkb:LSM1(gene name)|psi-mi:LSM1(display_short)|uniprotkb:CASM(gene name synonym)|uniprotkb:Cancer-associated Sm-like(gene name synonym)|uniprotkb:Small nuclear ribonuclear CaSm(gene name synonym) psi-mi:lsm5_human(display_long)|uniprotkb:LSM5(gene name)|psi-mi:LSM5(display_short) psi-mi:"MI:0226"(ion exchange chromatography) Scheller et al. (2009) pubmed:19628699|doi:10.1073/pnas.0906413106|imex:IM-14991 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15795343|imex:IM-14991-1|dip:DIP-185534E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055277.1|dip:DIP-31130N|ensembl:ENSG00000175324(gene)|ensembl:ENST00000311351(transcript)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000375"(RNA splicing, via transesterification reactions)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016070"(RNA metabolic process)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0071044"(histone mRNA catabolic process)|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:1990726"(Lsm1-7-Pat1 complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR034104|interpro:IPR044642|reactome:R-HSA-430039|go:"GO:0000932"(P-body) refseq:NP_001124182.1|refseq:NP_001132971.1|refseq:NP_036454.1|dip:DIP-31162N|ensembl:ENSG00000106355(gene)|ensembl:ENST00000450169(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005688"(U6 snRNP)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0009617"(response to bacterium)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0120115"(Lsm2-8 complex)|go:"GO:1990726"(Lsm1-7-Pat1 complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR033871|mint:Q9Y4Y9|rcsb pdb:3JCR|rcsb pdb:5O9Z|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:7ABG|reactome:R-HSA-430039|reactome:R-HSA-72163 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/06 2017/08/10 rogid:4ZjCoUTZoEAWqp5wvQDTcTr4gs49606 rogid:EeF2r4qY+BFrZTyTCT+i4ccskf49606 rigid:NM27m+uiRA+tscx/tl1b2MNgNAc false - - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:O15116 uniprotkb:P62312 intact:EBI-347619|uniprotkb:B2R5E6|ensembl:ENSP00000310596 intact:EBI-373310|uniprotkb:Q9Y4Y8|uniprotkb:Q4W5J5|ensembl:ENSP00000296581|ensembl:ENSP00000420929|ensembl:ENSP00000422392|ensembl:ENSP00000427036|ensembl:ENSP00000497311 psi-mi:lsm1_human(display_long)|uniprotkb:LSM1(gene name)|psi-mi:LSM1(display_short)|uniprotkb:CASM(gene name synonym)|uniprotkb:Cancer-associated Sm-like(gene name synonym)|uniprotkb:Small nuclear ribonuclear CaSm(gene name synonym) psi-mi:lsm6_human(display_long)|uniprotkb:LSM6(gene name)|psi-mi:LSM6(display_short) psi-mi:"MI:0226"(ion exchange chromatography) Scheller et al. (2009) pubmed:19628699|doi:10.1073/pnas.0906413106|imex:IM-14991 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15795343|imex:IM-14991-1|dip:DIP-185534E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055277.1|dip:DIP-31130N|ensembl:ENSG00000175324(gene)|ensembl:ENST00000311351(transcript)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000375"(RNA splicing, via transesterification reactions)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016070"(RNA metabolic process)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0071044"(histone mRNA catabolic process)|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:1990726"(Lsm1-7-Pat1 complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR034104|interpro:IPR044642|reactome:R-HSA-430039|go:"GO:0000932"(P-body) refseq:NP_009011.1|ensembl:ENSG00000164167(gene)|ensembl:ENST00000296581(transcript)|ensembl:ENST00000502781(transcript)|ensembl:ENST00000504181(transcript)|ensembl:ENST00000515311(transcript)|ensembl:ENST00000649747(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005688"(U6 snRNP)|go:"GO:0005730"(nucleolus)|go:"GO:0005732"("sno(s)RNA-containing ribonucleoprotein complex")|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0008033"(tRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0030490"(maturation of SSU-rRNA)|go:"GO:0030532"(small nuclear ribonucleoprotein complex)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0120115"(Lsm2-8 complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR016487(Small nuclear ribonucleoprotein SmF)|mint:P62312|rcsb pdb:3JCR|rcsb pdb:5O9Z|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:7ABG|reactome:R-HSA-430039|reactome:R-HSA-72163|refseq:XP_016863161.1|refseq:XP_016863162.1|dip:DIP-31128N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/06 2017/08/10 rogid:4ZjCoUTZoEAWqp5wvQDTcTr4gs49606 rogid:knWeW+soIyeLSg0Xbe79er748hE9606 rigid:NM27m+uiRA+tscx/tl1b2MNgNAc false - - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:O15116 uniprotkb:Q9UK45 intact:EBI-347619|uniprotkb:B2R5E6|ensembl:ENSP00000310596 intact:EBI-348372|ensembl:ENSP00000252622 psi-mi:lsm1_human(display_long)|uniprotkb:LSM1(gene name)|psi-mi:LSM1(display_short)|uniprotkb:CASM(gene name synonym)|uniprotkb:Cancer-associated Sm-like(gene name synonym)|uniprotkb:Small nuclear ribonuclear CaSm(gene name synonym) psi-mi:lsm7_human(display_long)|uniprotkb:LSM7(gene name)|psi-mi:LSM7(display_short) psi-mi:"MI:0226"(ion exchange chromatography) Scheller et al. (2009) pubmed:19628699|doi:10.1073/pnas.0906413106|imex:IM-14991 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15795343|imex:IM-14991-1|dip:DIP-185534E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055277.1|dip:DIP-31130N|ensembl:ENSG00000175324(gene)|ensembl:ENST00000311351(transcript)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000375"(RNA splicing, via transesterification reactions)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016070"(RNA metabolic process)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0071044"(histone mRNA catabolic process)|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:1990726"(Lsm1-7-Pat1 complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR034104|interpro:IPR044642|reactome:R-HSA-430039|go:"GO:0000932"(P-body) refseq:NP_057283.1|interpro:IPR017132(U6 snRNA-associated Sm-like protein LSm7)|interpro:IPR044641|rcsb pdb:3JCR|rcsb pdb:5O9Z|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:7ABG|reactome:R-HSA-430039|reactome:R-HSA-72163|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005829"(cytosol)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071004"(U2-type prespliceosome)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0097526"(spliceosomal tri-snRNP complex)|go:"GO:0120115"(Lsm2-8 complex)|go:"GO:1990726"(Lsm1-7-Pat1 complex)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|ensembl:ENSG00000130332(gene)|ensembl:ENST00000252622(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005688"(U6 snRNP)|dip:DIP-31129N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/06 2017/08/10 rogid:4ZjCoUTZoEAWqp5wvQDTcTr4gs49606 rogid:vT1gI3yzYl37cX++CUGdJowAL909606 rigid:NM27m+uiRA+tscx/tl1b2MNgNAc false - - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q9Y333 uniprotkb:P62310 intact:EBI-347416|uniprotkb:Q6FGG1|ensembl:ENSP00000414006|ensembl:ENSP00000414634|ensembl:ENSP00000406280|ensembl:ENSP00000364813|ensembl:ENSP00000372883|ensembl:ENSP00000403345 intact:EBI-348239|ensembl:ENSP00000302160|uniprotkb:Q9Y4Z1|uniprotkb:Q6IAH0 psi-mi:lsm2_human(display_long)|uniprotkb:LSM2(gene name)|psi-mi:LSM2(display_short)|uniprotkb:C6orf28(gene name synonym)|uniprotkb:G7B(gene name synonym)|uniprotkb:snRNP core Sm-like protein Sm-x5(gene name synonym)|uniprotkb:Small nuclear ribonuclear protein D homolog(gene name synonym)|uniprotkb:Protein G7b(gene name synonym) psi-mi:lsm3_human(display_long)|uniprotkb:MDS017(orf name)|uniprotkb:LSM3(gene name)|psi-mi:LSM3(display_short) psi-mi:"MI:0226"(ion exchange chromatography) Scheller et al. (2009) pubmed:19628699|doi:10.1073/pnas.0906413106|imex:IM-14991 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15795387|imex:IM-14991-3|dip:DIP-185535E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_067000.1|ensembl:ENST00000375661(transcript)|ensembl:ENST00000383391(transcript)|ensembl:ENST00000424975(transcript)|ensembl:ENST00000432122(transcript)|ensembl:ENST00000434125(transcript)|ensembl:ENST00000455705(transcript)|go:"GO:0000244"(spliceosomal tri-snRNP complex assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005688"(U6 snRNP)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0120115"(Lsm2-8 complex)|go:"GO:1990726"(Lsm1-7-Pat1 complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR016654(U6 snRNA-associated Sm-like protein LSm2)|mint:Q9Y333|rcsb pdb:3JCR|rcsb pdb:5O9Z|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:7ABG|reactome:R-HSA-430039|reactome:R-HSA-72163|reactome:R-HSA-72165|ensembl:ENSG00000172850(gene)|ensembl:ENSG00000204392(gene)|ensembl:ENSG00000224979(gene)|ensembl:ENSG00000225998(gene)|ensembl:ENSG00000231502(gene)|ensembl:ENSG00000236826(gene)|dip:DIP-31139N ensembl:ENSG00000170860(gene)|ensembl:ENST00000306024(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000932"(P-body)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005688"(U6 snRNP)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0030629"(U6 snRNA 3'-end binding)|go:"GO:0033962"(P-body assembly)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0120115"(Lsm2-8 complex)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:1990726"(Lsm1-7-Pat1 complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR034105|interpro:IPR040002|mint:P62310|rcsb pdb:3JCR|rcsb pdb:5O9Z|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:7ABG|reactome:R-HSA-430039|reactome:R-HSA-72163|refseq:NP_055278.1|dip:DIP-31218N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/06 2017/08/10 rogid:lReyYTJxC/WlYg/ekKaqZiNNdVM9606 rogid:+OnRI9eJcsd1xJe+cUCP7Y/9tt09606 rigid:EBQMeVQ80grv/xpvu9sB+W98lps false - - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q9Y333 uniprotkb:Q9Y4Z0 intact:EBI-347416|uniprotkb:Q6FGG1|ensembl:ENSP00000414006|ensembl:ENSP00000414634|ensembl:ENSP00000406280|ensembl:ENSP00000364813|ensembl:ENSP00000372883|ensembl:ENSP00000403345 intact:EBI-372521|ensembl:ENSP00000469468 psi-mi:lsm2_human(display_long)|uniprotkb:LSM2(gene name)|psi-mi:LSM2(display_short)|uniprotkb:C6orf28(gene name synonym)|uniprotkb:G7B(gene name synonym)|uniprotkb:snRNP core Sm-like protein Sm-x5(gene name synonym)|uniprotkb:Small nuclear ribonuclear protein D homolog(gene name synonym)|uniprotkb:Protein G7b(gene name synonym) psi-mi:lsm4_human(display_long)|uniprotkb:Glycine-rich protein(gene name synonym)|uniprotkb:LSM4(gene name)|psi-mi:LSM4(display_short) psi-mi:"MI:0226"(ion exchange chromatography) Scheller et al. (2009) pubmed:19628699|doi:10.1073/pnas.0906413106|imex:IM-14991 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15795387|imex:IM-14991-3|dip:DIP-185535E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_067000.1|ensembl:ENST00000375661(transcript)|ensembl:ENST00000383391(transcript)|ensembl:ENST00000424975(transcript)|ensembl:ENST00000432122(transcript)|ensembl:ENST00000434125(transcript)|ensembl:ENST00000455705(transcript)|go:"GO:0000244"(spliceosomal tri-snRNP complex assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005688"(U6 snRNP)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0120115"(Lsm2-8 complex)|go:"GO:1990726"(Lsm1-7-Pat1 complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR016654(U6 snRNA-associated Sm-like protein LSm2)|mint:Q9Y333|rcsb pdb:3JCR|rcsb pdb:5O9Z|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:7ABG|reactome:R-HSA-430039|reactome:R-HSA-72163|reactome:R-HSA-72165|ensembl:ENSG00000172850(gene)|ensembl:ENSG00000204392(gene)|ensembl:ENSG00000224979(gene)|ensembl:ENSG00000225998(gene)|ensembl:ENSG00000231502(gene)|ensembl:ENSG00000236826(gene)|dip:DIP-31139N refseq:NP_036453.1|ensembl:ENSG00000130520(gene)|ensembl:ENST00000593829(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000932"(P-body)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005688"(U6 snRNP)|go:"GO:0005829"(cytosol)|go:"GO:0008380"(RNA splicing)|go:"GO:0016020"(membrane)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033962"(P-body assembly)|go:"GO:0042731"(PH domain binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0043005"(neuron projection)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0097526"(spliceosomal tri-snRNP complex)|go:"GO:0120115"(Lsm2-8 complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR027141|interpro:IPR034101|rcsb pdb:3JCR|rcsb pdb:5O9Z|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:7ABG|reactome:R-HSA-430039|reactome:R-HSA-72163|dip:DIP-31209N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/06 2017/08/10 rogid:lReyYTJxC/WlYg/ekKaqZiNNdVM9606 rogid:FlaQveuBbixGvfX47pCm26xscT09606 rigid:EBQMeVQ80grv/xpvu9sB+W98lps false - - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q9Y333 uniprotkb:Q9Y4Y9 intact:EBI-347416|uniprotkb:Q6FGG1|ensembl:ENSP00000414006|ensembl:ENSP00000414634|ensembl:ENSP00000406280|ensembl:ENSP00000364813|ensembl:ENSP00000372883|ensembl:ENSP00000403345 intact:EBI-373007|ensembl:ENSP00000410758 psi-mi:lsm2_human(display_long)|uniprotkb:LSM2(gene name)|psi-mi:LSM2(display_short)|uniprotkb:C6orf28(gene name synonym)|uniprotkb:G7B(gene name synonym)|uniprotkb:snRNP core Sm-like protein Sm-x5(gene name synonym)|uniprotkb:Small nuclear ribonuclear protein D homolog(gene name synonym)|uniprotkb:Protein G7b(gene name synonym) psi-mi:lsm5_human(display_long)|uniprotkb:LSM5(gene name)|psi-mi:LSM5(display_short) psi-mi:"MI:0226"(ion exchange chromatography) Scheller et al. (2009) pubmed:19628699|doi:10.1073/pnas.0906413106|imex:IM-14991 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15795387|imex:IM-14991-3|dip:DIP-185535E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_067000.1|ensembl:ENST00000375661(transcript)|ensembl:ENST00000383391(transcript)|ensembl:ENST00000424975(transcript)|ensembl:ENST00000432122(transcript)|ensembl:ENST00000434125(transcript)|ensembl:ENST00000455705(transcript)|go:"GO:0000244"(spliceosomal tri-snRNP complex assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005688"(U6 snRNP)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0120115"(Lsm2-8 complex)|go:"GO:1990726"(Lsm1-7-Pat1 complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR016654(U6 snRNA-associated Sm-like protein LSm2)|mint:Q9Y333|rcsb pdb:3JCR|rcsb pdb:5O9Z|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:7ABG|reactome:R-HSA-430039|reactome:R-HSA-72163|reactome:R-HSA-72165|ensembl:ENSG00000172850(gene)|ensembl:ENSG00000204392(gene)|ensembl:ENSG00000224979(gene)|ensembl:ENSG00000225998(gene)|ensembl:ENSG00000231502(gene)|ensembl:ENSG00000236826(gene)|dip:DIP-31139N refseq:NP_001124182.1|refseq:NP_001132971.1|refseq:NP_036454.1|dip:DIP-31162N|ensembl:ENSG00000106355(gene)|ensembl:ENST00000450169(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005688"(U6 snRNP)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0009617"(response to bacterium)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0120115"(Lsm2-8 complex)|go:"GO:1990726"(Lsm1-7-Pat1 complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR033871|mint:Q9Y4Y9|rcsb pdb:3JCR|rcsb pdb:5O9Z|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:7ABG|reactome:R-HSA-430039|reactome:R-HSA-72163 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/06 2017/08/10 rogid:lReyYTJxC/WlYg/ekKaqZiNNdVM9606 rogid:EeF2r4qY+BFrZTyTCT+i4ccskf49606 rigid:EBQMeVQ80grv/xpvu9sB+W98lps false - - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q9Y333 uniprotkb:P62312 intact:EBI-347416|uniprotkb:Q6FGG1|ensembl:ENSP00000414006|ensembl:ENSP00000414634|ensembl:ENSP00000406280|ensembl:ENSP00000364813|ensembl:ENSP00000372883|ensembl:ENSP00000403345 intact:EBI-373310|uniprotkb:Q9Y4Y8|uniprotkb:Q4W5J5|ensembl:ENSP00000296581|ensembl:ENSP00000420929|ensembl:ENSP00000422392|ensembl:ENSP00000427036|ensembl:ENSP00000497311 psi-mi:lsm2_human(display_long)|uniprotkb:LSM2(gene name)|psi-mi:LSM2(display_short)|uniprotkb:C6orf28(gene name synonym)|uniprotkb:G7B(gene name synonym)|uniprotkb:snRNP core Sm-like protein Sm-x5(gene name synonym)|uniprotkb:Small nuclear ribonuclear protein D homolog(gene name synonym)|uniprotkb:Protein G7b(gene name synonym) psi-mi:lsm6_human(display_long)|uniprotkb:LSM6(gene name)|psi-mi:LSM6(display_short) psi-mi:"MI:0226"(ion exchange chromatography) Scheller et al. (2009) pubmed:19628699|doi:10.1073/pnas.0906413106|imex:IM-14991 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15795387|imex:IM-14991-3|dip:DIP-185535E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_067000.1|ensembl:ENST00000375661(transcript)|ensembl:ENST00000383391(transcript)|ensembl:ENST00000424975(transcript)|ensembl:ENST00000432122(transcript)|ensembl:ENST00000434125(transcript)|ensembl:ENST00000455705(transcript)|go:"GO:0000244"(spliceosomal tri-snRNP complex assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005688"(U6 snRNP)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0120115"(Lsm2-8 complex)|go:"GO:1990726"(Lsm1-7-Pat1 complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR016654(U6 snRNA-associated Sm-like protein LSm2)|mint:Q9Y333|rcsb pdb:3JCR|rcsb pdb:5O9Z|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:7ABG|reactome:R-HSA-430039|reactome:R-HSA-72163|reactome:R-HSA-72165|ensembl:ENSG00000172850(gene)|ensembl:ENSG00000204392(gene)|ensembl:ENSG00000224979(gene)|ensembl:ENSG00000225998(gene)|ensembl:ENSG00000231502(gene)|ensembl:ENSG00000236826(gene)|dip:DIP-31139N refseq:NP_009011.1|ensembl:ENSG00000164167(gene)|ensembl:ENST00000296581(transcript)|ensembl:ENST00000502781(transcript)|ensembl:ENST00000504181(transcript)|ensembl:ENST00000515311(transcript)|ensembl:ENST00000649747(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005688"(U6 snRNP)|go:"GO:0005730"(nucleolus)|go:"GO:0005732"("sno(s)RNA-containing ribonucleoprotein complex")|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0008033"(tRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0030490"(maturation of SSU-rRNA)|go:"GO:0030532"(small nuclear ribonucleoprotein complex)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0120115"(Lsm2-8 complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR016487(Small nuclear ribonucleoprotein SmF)|mint:P62312|rcsb pdb:3JCR|rcsb pdb:5O9Z|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:7ABG|reactome:R-HSA-430039|reactome:R-HSA-72163|refseq:XP_016863161.1|refseq:XP_016863162.1|dip:DIP-31128N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/06 2017/08/10 rogid:lReyYTJxC/WlYg/ekKaqZiNNdVM9606 rogid:knWeW+soIyeLSg0Xbe79er748hE9606 rigid:EBQMeVQ80grv/xpvu9sB+W98lps false - - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q9Y333 uniprotkb:Q9UK45 intact:EBI-347416|uniprotkb:Q6FGG1|ensembl:ENSP00000414006|ensembl:ENSP00000414634|ensembl:ENSP00000406280|ensembl:ENSP00000364813|ensembl:ENSP00000372883|ensembl:ENSP00000403345 intact:EBI-348372|ensembl:ENSP00000252622 psi-mi:lsm2_human(display_long)|uniprotkb:LSM2(gene name)|psi-mi:LSM2(display_short)|uniprotkb:C6orf28(gene name synonym)|uniprotkb:G7B(gene name synonym)|uniprotkb:snRNP core Sm-like protein Sm-x5(gene name synonym)|uniprotkb:Small nuclear ribonuclear protein D homolog(gene name synonym)|uniprotkb:Protein G7b(gene name synonym) psi-mi:lsm7_human(display_long)|uniprotkb:LSM7(gene name)|psi-mi:LSM7(display_short) psi-mi:"MI:0226"(ion exchange chromatography) Scheller et al. (2009) pubmed:19628699|doi:10.1073/pnas.0906413106|imex:IM-14991 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15795387|imex:IM-14991-3|dip:DIP-185535E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_067000.1|ensembl:ENST00000375661(transcript)|ensembl:ENST00000383391(transcript)|ensembl:ENST00000424975(transcript)|ensembl:ENST00000432122(transcript)|ensembl:ENST00000434125(transcript)|ensembl:ENST00000455705(transcript)|go:"GO:0000244"(spliceosomal tri-snRNP complex assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005688"(U6 snRNP)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0120115"(Lsm2-8 complex)|go:"GO:1990726"(Lsm1-7-Pat1 complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR016654(U6 snRNA-associated Sm-like protein LSm2)|mint:Q9Y333|rcsb pdb:3JCR|rcsb pdb:5O9Z|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:7ABG|reactome:R-HSA-430039|reactome:R-HSA-72163|reactome:R-HSA-72165|ensembl:ENSG00000172850(gene)|ensembl:ENSG00000204392(gene)|ensembl:ENSG00000224979(gene)|ensembl:ENSG00000225998(gene)|ensembl:ENSG00000231502(gene)|ensembl:ENSG00000236826(gene)|dip:DIP-31139N refseq:NP_057283.1|interpro:IPR017132(U6 snRNA-associated Sm-like protein LSm7)|interpro:IPR044641|rcsb pdb:3JCR|rcsb pdb:5O9Z|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:7ABG|reactome:R-HSA-430039|reactome:R-HSA-72163|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005829"(cytosol)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071004"(U2-type prespliceosome)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0097526"(spliceosomal tri-snRNP complex)|go:"GO:0120115"(Lsm2-8 complex)|go:"GO:1990726"(Lsm1-7-Pat1 complex)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|ensembl:ENSG00000130332(gene)|ensembl:ENST00000252622(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005688"(U6 snRNP)|dip:DIP-31129N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/06 2017/08/10 rogid:lReyYTJxC/WlYg/ekKaqZiNNdVM9606 rogid:vT1gI3yzYl37cX++CUGdJowAL909606 rigid:EBQMeVQ80grv/xpvu9sB+W98lps false - - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q9Y333 uniprotkb:O95777 intact:EBI-347416|uniprotkb:Q6FGG1|ensembl:ENSP00000414006|ensembl:ENSP00000414634|ensembl:ENSP00000406280|ensembl:ENSP00000364813|ensembl:ENSP00000372883|ensembl:ENSP00000403345 intact:EBI-347779|ensembl:ENSP00000249299 psi-mi:lsm2_human(display_long)|uniprotkb:LSM2(gene name)|psi-mi:LSM2(display_short)|uniprotkb:C6orf28(gene name synonym)|uniprotkb:G7B(gene name synonym)|uniprotkb:snRNP core Sm-like protein Sm-x5(gene name synonym)|uniprotkb:Small nuclear ribonuclear protein D homolog(gene name synonym)|uniprotkb:Protein G7b(gene name synonym) psi-mi:lsm8_human(display_long)|uniprotkb:LSM8(gene name)|psi-mi:LSM8(display_short) psi-mi:"MI:0226"(ion exchange chromatography) Scheller et al. (2009) pubmed:19628699|doi:10.1073/pnas.0906413106|imex:IM-14991 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15795387|imex:IM-14991-3|dip:DIP-185535E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_067000.1|ensembl:ENST00000375661(transcript)|ensembl:ENST00000383391(transcript)|ensembl:ENST00000424975(transcript)|ensembl:ENST00000432122(transcript)|ensembl:ENST00000434125(transcript)|ensembl:ENST00000455705(transcript)|go:"GO:0000244"(spliceosomal tri-snRNP complex assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005688"(U6 snRNP)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0120115"(Lsm2-8 complex)|go:"GO:1990726"(Lsm1-7-Pat1 complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR016654(U6 snRNA-associated Sm-like protein LSm2)|mint:Q9Y333|rcsb pdb:3JCR|rcsb pdb:5O9Z|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:7ABG|reactome:R-HSA-430039|reactome:R-HSA-72163|reactome:R-HSA-72165|ensembl:ENSG00000172850(gene)|ensembl:ENSG00000204392(gene)|ensembl:ENSG00000224979(gene)|ensembl:ENSG00000225998(gene)|ensembl:ENSG00000231502(gene)|ensembl:ENSG00000236826(gene)|dip:DIP-31139N refseq:NP_057284.1|dip:DIP-31195N|ensembl:ENSG00000128534(gene)|ensembl:ENST00000249299(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005688"(U6 snRNP)|go:"GO:0016070"(RNA metabolic process)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0120115"(Lsm2-8 complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR034103|interpro:IPR044642|rcsb pdb:3JCR|rcsb pdb:5O9Z|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:7ABG|reactome:R-HSA-72163 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/06 2017/08/10 rogid:lReyYTJxC/WlYg/ekKaqZiNNdVM9606 rogid:Kyf8IAEIkbe1s2NnqxqGA1o6BbU9606 rigid:EBQMeVQ80grv/xpvu9sB+W98lps false - - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:O15116 uniprotkb:Q9Y333 intact:EBI-347619|uniprotkb:B2R5E6|ensembl:ENSP00000310596 intact:EBI-347416|uniprotkb:Q6FGG1|ensembl:ENSP00000414006|ensembl:ENSP00000414634|ensembl:ENSP00000406280|ensembl:ENSP00000364813|ensembl:ENSP00000372883|ensembl:ENSP00000403345 psi-mi:lsm1_human(display_long)|uniprotkb:LSM1(gene name)|psi-mi:LSM1(display_short)|uniprotkb:CASM(gene name synonym)|uniprotkb:Cancer-associated Sm-like(gene name synonym)|uniprotkb:Small nuclear ribonuclear CaSm(gene name synonym) psi-mi:lsm2_human(display_long)|uniprotkb:LSM2(gene name)|psi-mi:LSM2(display_short)|uniprotkb:C6orf28(gene name synonym)|uniprotkb:G7B(gene name synonym)|uniprotkb:snRNP core Sm-like protein Sm-x5(gene name synonym)|uniprotkb:Small nuclear ribonuclear protein D homolog(gene name synonym)|uniprotkb:Protein G7b(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Scheller et al. (2009) pubmed:19628699|doi:10.1073/pnas.0906413106|imex:IM-14991 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15795365|imex:IM-14991-2|dip:DIP-185534E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055277.1|dip:DIP-31130N|ensembl:ENSG00000175324(gene)|ensembl:ENST00000311351(transcript)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000375"(RNA splicing, via transesterification reactions)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016070"(RNA metabolic process)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0071044"(histone mRNA catabolic process)|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:1990726"(Lsm1-7-Pat1 complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR034104|interpro:IPR044642|reactome:R-HSA-430039|go:"GO:0000932"(P-body) refseq:NP_067000.1|ensembl:ENST00000375661(transcript)|ensembl:ENST00000383391(transcript)|ensembl:ENST00000424975(transcript)|ensembl:ENST00000432122(transcript)|ensembl:ENST00000434125(transcript)|ensembl:ENST00000455705(transcript)|go:"GO:0000244"(spliceosomal tri-snRNP complex assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005688"(U6 snRNP)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0120115"(Lsm2-8 complex)|go:"GO:1990726"(Lsm1-7-Pat1 complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR016654(U6 snRNA-associated Sm-like protein LSm2)|mint:Q9Y333|rcsb pdb:3JCR|rcsb pdb:5O9Z|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:7ABG|reactome:R-HSA-430039|reactome:R-HSA-72163|reactome:R-HSA-72165|ensembl:ENSG00000172850(gene)|ensembl:ENSG00000204392(gene)|ensembl:ENSG00000224979(gene)|ensembl:ENSG00000225998(gene)|ensembl:ENSG00000231502(gene)|ensembl:ENSG00000236826(gene)|dip:DIP-31139N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/06 2017/08/10 rogid:4ZjCoUTZoEAWqp5wvQDTcTr4gs49606 rogid:lReyYTJxC/WlYg/ekKaqZiNNdVM9606 rigid:NM27m+uiRA+tscx/tl1b2MNgNAc false - - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:O15116 uniprotkb:P62310 intact:EBI-347619|uniprotkb:B2R5E6|ensembl:ENSP00000310596 intact:EBI-348239|ensembl:ENSP00000302160|uniprotkb:Q9Y4Z1|uniprotkb:Q6IAH0 psi-mi:lsm1_human(display_long)|uniprotkb:LSM1(gene name)|psi-mi:LSM1(display_short)|uniprotkb:CASM(gene name synonym)|uniprotkb:Cancer-associated Sm-like(gene name synonym)|uniprotkb:Small nuclear ribonuclear CaSm(gene name synonym) psi-mi:lsm3_human(display_long)|uniprotkb:MDS017(orf name)|uniprotkb:LSM3(gene name)|psi-mi:LSM3(display_short) psi-mi:"MI:0071"(molecular sieving) Scheller et al. (2009) pubmed:19628699|doi:10.1073/pnas.0906413106|imex:IM-14991 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15795365|imex:IM-14991-2|dip:DIP-185534E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055277.1|dip:DIP-31130N|ensembl:ENSG00000175324(gene)|ensembl:ENST00000311351(transcript)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000375"(RNA splicing, via transesterification reactions)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016070"(RNA metabolic process)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0071044"(histone mRNA catabolic process)|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:1990726"(Lsm1-7-Pat1 complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR034104|interpro:IPR044642|reactome:R-HSA-430039|go:"GO:0000932"(P-body) ensembl:ENSG00000170860(gene)|ensembl:ENST00000306024(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000932"(P-body)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005688"(U6 snRNP)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0030629"(U6 snRNA 3'-end binding)|go:"GO:0033962"(P-body assembly)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0120115"(Lsm2-8 complex)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:1990726"(Lsm1-7-Pat1 complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR034105|interpro:IPR040002|mint:P62310|rcsb pdb:3JCR|rcsb pdb:5O9Z|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:7ABG|reactome:R-HSA-430039|reactome:R-HSA-72163|refseq:NP_055278.1|dip:DIP-31218N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/06 2017/08/10 rogid:4ZjCoUTZoEAWqp5wvQDTcTr4gs49606 rogid:+OnRI9eJcsd1xJe+cUCP7Y/9tt09606 rigid:NM27m+uiRA+tscx/tl1b2MNgNAc false - - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:O15116 uniprotkb:Q9Y4Z0 intact:EBI-347619|uniprotkb:B2R5E6|ensembl:ENSP00000310596 intact:EBI-372521|ensembl:ENSP00000469468 psi-mi:lsm1_human(display_long)|uniprotkb:LSM1(gene name)|psi-mi:LSM1(display_short)|uniprotkb:CASM(gene name synonym)|uniprotkb:Cancer-associated Sm-like(gene name synonym)|uniprotkb:Small nuclear ribonuclear CaSm(gene name synonym) psi-mi:lsm4_human(display_long)|uniprotkb:Glycine-rich protein(gene name synonym)|uniprotkb:LSM4(gene name)|psi-mi:LSM4(display_short) psi-mi:"MI:0071"(molecular sieving) Scheller et al. (2009) pubmed:19628699|doi:10.1073/pnas.0906413106|imex:IM-14991 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15795365|imex:IM-14991-2|dip:DIP-185534E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055277.1|dip:DIP-31130N|ensembl:ENSG00000175324(gene)|ensembl:ENST00000311351(transcript)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000375"(RNA splicing, via transesterification reactions)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016070"(RNA metabolic process)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0071044"(histone mRNA catabolic process)|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:1990726"(Lsm1-7-Pat1 complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR034104|interpro:IPR044642|reactome:R-HSA-430039|go:"GO:0000932"(P-body) refseq:NP_036453.1|ensembl:ENSG00000130520(gene)|ensembl:ENST00000593829(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000932"(P-body)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005688"(U6 snRNP)|go:"GO:0005829"(cytosol)|go:"GO:0008380"(RNA splicing)|go:"GO:0016020"(membrane)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033962"(P-body assembly)|go:"GO:0042731"(PH domain binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0043005"(neuron projection)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0097526"(spliceosomal tri-snRNP complex)|go:"GO:0120115"(Lsm2-8 complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR027141|interpro:IPR034101|rcsb pdb:3JCR|rcsb pdb:5O9Z|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:7ABG|reactome:R-HSA-430039|reactome:R-HSA-72163|dip:DIP-31209N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/06 2017/08/10 rogid:4ZjCoUTZoEAWqp5wvQDTcTr4gs49606 rogid:FlaQveuBbixGvfX47pCm26xscT09606 rigid:NM27m+uiRA+tscx/tl1b2MNgNAc false - - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:O15116 uniprotkb:Q9Y4Y9 intact:EBI-347619|uniprotkb:B2R5E6|ensembl:ENSP00000310596 intact:EBI-373007|ensembl:ENSP00000410758 psi-mi:lsm1_human(display_long)|uniprotkb:LSM1(gene name)|psi-mi:LSM1(display_short)|uniprotkb:CASM(gene name synonym)|uniprotkb:Cancer-associated Sm-like(gene name synonym)|uniprotkb:Small nuclear ribonuclear CaSm(gene name synonym) psi-mi:lsm5_human(display_long)|uniprotkb:LSM5(gene name)|psi-mi:LSM5(display_short) psi-mi:"MI:0071"(molecular sieving) Scheller et al. (2009) pubmed:19628699|doi:10.1073/pnas.0906413106|imex:IM-14991 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15795365|imex:IM-14991-2|dip:DIP-185534E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055277.1|dip:DIP-31130N|ensembl:ENSG00000175324(gene)|ensembl:ENST00000311351(transcript)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000375"(RNA splicing, via transesterification reactions)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016070"(RNA metabolic process)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0071044"(histone mRNA catabolic process)|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:1990726"(Lsm1-7-Pat1 complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR034104|interpro:IPR044642|reactome:R-HSA-430039|go:"GO:0000932"(P-body) refseq:NP_001124182.1|refseq:NP_001132971.1|refseq:NP_036454.1|dip:DIP-31162N|ensembl:ENSG00000106355(gene)|ensembl:ENST00000450169(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005688"(U6 snRNP)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0009617"(response to bacterium)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0120115"(Lsm2-8 complex)|go:"GO:1990726"(Lsm1-7-Pat1 complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR033871|mint:Q9Y4Y9|rcsb pdb:3JCR|rcsb pdb:5O9Z|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:7ABG|reactome:R-HSA-430039|reactome:R-HSA-72163 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/06 2017/08/10 rogid:4ZjCoUTZoEAWqp5wvQDTcTr4gs49606 rogid:EeF2r4qY+BFrZTyTCT+i4ccskf49606 rigid:NM27m+uiRA+tscx/tl1b2MNgNAc false - - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:O15116 uniprotkb:P62312 intact:EBI-347619|uniprotkb:B2R5E6|ensembl:ENSP00000310596 intact:EBI-373310|uniprotkb:Q9Y4Y8|uniprotkb:Q4W5J5|ensembl:ENSP00000296581|ensembl:ENSP00000420929|ensembl:ENSP00000422392|ensembl:ENSP00000427036|ensembl:ENSP00000497311 psi-mi:lsm1_human(display_long)|uniprotkb:LSM1(gene name)|psi-mi:LSM1(display_short)|uniprotkb:CASM(gene name synonym)|uniprotkb:Cancer-associated Sm-like(gene name synonym)|uniprotkb:Small nuclear ribonuclear CaSm(gene name synonym) psi-mi:lsm6_human(display_long)|uniprotkb:LSM6(gene name)|psi-mi:LSM6(display_short) psi-mi:"MI:0071"(molecular sieving) Scheller et al. (2009) pubmed:19628699|doi:10.1073/pnas.0906413106|imex:IM-14991 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15795365|imex:IM-14991-2|dip:DIP-185534E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055277.1|dip:DIP-31130N|ensembl:ENSG00000175324(gene)|ensembl:ENST00000311351(transcript)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000375"(RNA splicing, via transesterification reactions)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016070"(RNA metabolic process)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0071044"(histone mRNA catabolic process)|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:1990726"(Lsm1-7-Pat1 complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR034104|interpro:IPR044642|reactome:R-HSA-430039|go:"GO:0000932"(P-body) refseq:NP_009011.1|ensembl:ENSG00000164167(gene)|ensembl:ENST00000296581(transcript)|ensembl:ENST00000502781(transcript)|ensembl:ENST00000504181(transcript)|ensembl:ENST00000515311(transcript)|ensembl:ENST00000649747(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005688"(U6 snRNP)|go:"GO:0005730"(nucleolus)|go:"GO:0005732"("sno(s)RNA-containing ribonucleoprotein complex")|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0008033"(tRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0030490"(maturation of SSU-rRNA)|go:"GO:0030532"(small nuclear ribonucleoprotein complex)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0120115"(Lsm2-8 complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR016487(Small nuclear ribonucleoprotein SmF)|mint:P62312|rcsb pdb:3JCR|rcsb pdb:5O9Z|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:7ABG|reactome:R-HSA-430039|reactome:R-HSA-72163|refseq:XP_016863161.1|refseq:XP_016863162.1|dip:DIP-31128N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/06 2017/08/10 rogid:4ZjCoUTZoEAWqp5wvQDTcTr4gs49606 rogid:knWeW+soIyeLSg0Xbe79er748hE9606 rigid:NM27m+uiRA+tscx/tl1b2MNgNAc false - - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:O15116 uniprotkb:Q9UK45 intact:EBI-347619|uniprotkb:B2R5E6|ensembl:ENSP00000310596 intact:EBI-348372|ensembl:ENSP00000252622 psi-mi:lsm1_human(display_long)|uniprotkb:LSM1(gene name)|psi-mi:LSM1(display_short)|uniprotkb:CASM(gene name synonym)|uniprotkb:Cancer-associated Sm-like(gene name synonym)|uniprotkb:Small nuclear ribonuclear CaSm(gene name synonym) psi-mi:lsm7_human(display_long)|uniprotkb:LSM7(gene name)|psi-mi:LSM7(display_short) psi-mi:"MI:0071"(molecular sieving) Scheller et al. (2009) pubmed:19628699|doi:10.1073/pnas.0906413106|imex:IM-14991 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15795365|imex:IM-14991-2|dip:DIP-185534E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055277.1|dip:DIP-31130N|ensembl:ENSG00000175324(gene)|ensembl:ENST00000311351(transcript)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000375"(RNA splicing, via transesterification reactions)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016070"(RNA metabolic process)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0071044"(histone mRNA catabolic process)|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:1990726"(Lsm1-7-Pat1 complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR034104|interpro:IPR044642|reactome:R-HSA-430039|go:"GO:0000932"(P-body) refseq:NP_057283.1|interpro:IPR017132(U6 snRNA-associated Sm-like protein LSm7)|interpro:IPR044641|rcsb pdb:3JCR|rcsb pdb:5O9Z|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:7ABG|reactome:R-HSA-430039|reactome:R-HSA-72163|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005829"(cytosol)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071004"(U2-type prespliceosome)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0097526"(spliceosomal tri-snRNP complex)|go:"GO:0120115"(Lsm2-8 complex)|go:"GO:1990726"(Lsm1-7-Pat1 complex)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|ensembl:ENSG00000130332(gene)|ensembl:ENST00000252622(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005688"(U6 snRNP)|dip:DIP-31129N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/06 2017/08/10 rogid:4ZjCoUTZoEAWqp5wvQDTcTr4gs49606 rogid:vT1gI3yzYl37cX++CUGdJowAL909606 rigid:NM27m+uiRA+tscx/tl1b2MNgNAc false - - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q9Y333 uniprotkb:P62310 intact:EBI-347416|uniprotkb:Q6FGG1|ensembl:ENSP00000414006|ensembl:ENSP00000414634|ensembl:ENSP00000406280|ensembl:ENSP00000364813|ensembl:ENSP00000372883|ensembl:ENSP00000403345 intact:EBI-348239|ensembl:ENSP00000302160|uniprotkb:Q9Y4Z1|uniprotkb:Q6IAH0 psi-mi:lsm2_human(display_long)|uniprotkb:LSM2(gene name)|psi-mi:LSM2(display_short)|uniprotkb:C6orf28(gene name synonym)|uniprotkb:G7B(gene name synonym)|uniprotkb:snRNP core Sm-like protein Sm-x5(gene name synonym)|uniprotkb:Small nuclear ribonuclear protein D homolog(gene name synonym)|uniprotkb:Protein G7b(gene name synonym) psi-mi:lsm3_human(display_long)|uniprotkb:MDS017(orf name)|uniprotkb:LSM3(gene name)|psi-mi:LSM3(display_short) psi-mi:"MI:0071"(molecular sieving) Scheller et al. (2009) pubmed:19628699|doi:10.1073/pnas.0906413106|imex:IM-14991 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15795409|imex:IM-14991-4|dip:DIP-185535E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_067000.1|ensembl:ENST00000375661(transcript)|ensembl:ENST00000383391(transcript)|ensembl:ENST00000424975(transcript)|ensembl:ENST00000432122(transcript)|ensembl:ENST00000434125(transcript)|ensembl:ENST00000455705(transcript)|go:"GO:0000244"(spliceosomal tri-snRNP complex assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005688"(U6 snRNP)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0120115"(Lsm2-8 complex)|go:"GO:1990726"(Lsm1-7-Pat1 complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR016654(U6 snRNA-associated Sm-like protein LSm2)|mint:Q9Y333|rcsb pdb:3JCR|rcsb pdb:5O9Z|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:7ABG|reactome:R-HSA-430039|reactome:R-HSA-72163|reactome:R-HSA-72165|ensembl:ENSG00000172850(gene)|ensembl:ENSG00000204392(gene)|ensembl:ENSG00000224979(gene)|ensembl:ENSG00000225998(gene)|ensembl:ENSG00000231502(gene)|ensembl:ENSG00000236826(gene)|dip:DIP-31139N ensembl:ENSG00000170860(gene)|ensembl:ENST00000306024(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000932"(P-body)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005688"(U6 snRNP)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0030629"(U6 snRNA 3'-end binding)|go:"GO:0033962"(P-body assembly)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0120115"(Lsm2-8 complex)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:1990726"(Lsm1-7-Pat1 complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR034105|interpro:IPR040002|mint:P62310|rcsb pdb:3JCR|rcsb pdb:5O9Z|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:7ABG|reactome:R-HSA-430039|reactome:R-HSA-72163|refseq:NP_055278.1|dip:DIP-31218N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/06 2017/08/10 rogid:lReyYTJxC/WlYg/ekKaqZiNNdVM9606 rogid:+OnRI9eJcsd1xJe+cUCP7Y/9tt09606 rigid:EBQMeVQ80grv/xpvu9sB+W98lps false - - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q9Y333 uniprotkb:Q9Y4Z0 intact:EBI-347416|uniprotkb:Q6FGG1|ensembl:ENSP00000414006|ensembl:ENSP00000414634|ensembl:ENSP00000406280|ensembl:ENSP00000364813|ensembl:ENSP00000372883|ensembl:ENSP00000403345 intact:EBI-372521|ensembl:ENSP00000469468 psi-mi:lsm2_human(display_long)|uniprotkb:LSM2(gene name)|psi-mi:LSM2(display_short)|uniprotkb:C6orf28(gene name synonym)|uniprotkb:G7B(gene name synonym)|uniprotkb:snRNP core Sm-like protein Sm-x5(gene name synonym)|uniprotkb:Small nuclear ribonuclear protein D homolog(gene name synonym)|uniprotkb:Protein G7b(gene name synonym) psi-mi:lsm4_human(display_long)|uniprotkb:Glycine-rich protein(gene name synonym)|uniprotkb:LSM4(gene name)|psi-mi:LSM4(display_short) psi-mi:"MI:0071"(molecular sieving) Scheller et al. (2009) pubmed:19628699|doi:10.1073/pnas.0906413106|imex:IM-14991 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15795409|imex:IM-14991-4|dip:DIP-185535E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_067000.1|ensembl:ENST00000375661(transcript)|ensembl:ENST00000383391(transcript)|ensembl:ENST00000424975(transcript)|ensembl:ENST00000432122(transcript)|ensembl:ENST00000434125(transcript)|ensembl:ENST00000455705(transcript)|go:"GO:0000244"(spliceosomal tri-snRNP complex assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005688"(U6 snRNP)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0120115"(Lsm2-8 complex)|go:"GO:1990726"(Lsm1-7-Pat1 complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR016654(U6 snRNA-associated Sm-like protein LSm2)|mint:Q9Y333|rcsb pdb:3JCR|rcsb pdb:5O9Z|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:7ABG|reactome:R-HSA-430039|reactome:R-HSA-72163|reactome:R-HSA-72165|ensembl:ENSG00000172850(gene)|ensembl:ENSG00000204392(gene)|ensembl:ENSG00000224979(gene)|ensembl:ENSG00000225998(gene)|ensembl:ENSG00000231502(gene)|ensembl:ENSG00000236826(gene)|dip:DIP-31139N refseq:NP_036453.1|ensembl:ENSG00000130520(gene)|ensembl:ENST00000593829(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000932"(P-body)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005688"(U6 snRNP)|go:"GO:0005829"(cytosol)|go:"GO:0008380"(RNA splicing)|go:"GO:0016020"(membrane)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033962"(P-body assembly)|go:"GO:0042731"(PH domain binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0043005"(neuron projection)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0097526"(spliceosomal tri-snRNP complex)|go:"GO:0120115"(Lsm2-8 complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR027141|interpro:IPR034101|rcsb pdb:3JCR|rcsb pdb:5O9Z|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:7ABG|reactome:R-HSA-430039|reactome:R-HSA-72163|dip:DIP-31209N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/06 2017/08/10 rogid:lReyYTJxC/WlYg/ekKaqZiNNdVM9606 rogid:FlaQveuBbixGvfX47pCm26xscT09606 rigid:EBQMeVQ80grv/xpvu9sB+W98lps false - - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q9Y333 uniprotkb:Q9Y4Y9 intact:EBI-347416|uniprotkb:Q6FGG1|ensembl:ENSP00000414006|ensembl:ENSP00000414634|ensembl:ENSP00000406280|ensembl:ENSP00000364813|ensembl:ENSP00000372883|ensembl:ENSP00000403345 intact:EBI-373007|ensembl:ENSP00000410758 psi-mi:lsm2_human(display_long)|uniprotkb:LSM2(gene name)|psi-mi:LSM2(display_short)|uniprotkb:C6orf28(gene name synonym)|uniprotkb:G7B(gene name synonym)|uniprotkb:snRNP core Sm-like protein Sm-x5(gene name synonym)|uniprotkb:Small nuclear ribonuclear protein D homolog(gene name synonym)|uniprotkb:Protein G7b(gene name synonym) psi-mi:lsm5_human(display_long)|uniprotkb:LSM5(gene name)|psi-mi:LSM5(display_short) psi-mi:"MI:0071"(molecular sieving) Scheller et al. (2009) pubmed:19628699|doi:10.1073/pnas.0906413106|imex:IM-14991 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15795409|imex:IM-14991-4|dip:DIP-185535E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_067000.1|ensembl:ENST00000375661(transcript)|ensembl:ENST00000383391(transcript)|ensembl:ENST00000424975(transcript)|ensembl:ENST00000432122(transcript)|ensembl:ENST00000434125(transcript)|ensembl:ENST00000455705(transcript)|go:"GO:0000244"(spliceosomal tri-snRNP complex assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005688"(U6 snRNP)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0120115"(Lsm2-8 complex)|go:"GO:1990726"(Lsm1-7-Pat1 complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR016654(U6 snRNA-associated Sm-like protein LSm2)|mint:Q9Y333|rcsb pdb:3JCR|rcsb pdb:5O9Z|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:7ABG|reactome:R-HSA-430039|reactome:R-HSA-72163|reactome:R-HSA-72165|ensembl:ENSG00000172850(gene)|ensembl:ENSG00000204392(gene)|ensembl:ENSG00000224979(gene)|ensembl:ENSG00000225998(gene)|ensembl:ENSG00000231502(gene)|ensembl:ENSG00000236826(gene)|dip:DIP-31139N refseq:NP_001124182.1|refseq:NP_001132971.1|refseq:NP_036454.1|dip:DIP-31162N|ensembl:ENSG00000106355(gene)|ensembl:ENST00000450169(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005688"(U6 snRNP)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0009617"(response to bacterium)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0120115"(Lsm2-8 complex)|go:"GO:1990726"(Lsm1-7-Pat1 complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR033871|mint:Q9Y4Y9|rcsb pdb:3JCR|rcsb pdb:5O9Z|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:7ABG|reactome:R-HSA-430039|reactome:R-HSA-72163 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/06 2017/08/10 rogid:lReyYTJxC/WlYg/ekKaqZiNNdVM9606 rogid:EeF2r4qY+BFrZTyTCT+i4ccskf49606 rigid:EBQMeVQ80grv/xpvu9sB+W98lps false - - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q9Y333 uniprotkb:P62312 intact:EBI-347416|uniprotkb:Q6FGG1|ensembl:ENSP00000414006|ensembl:ENSP00000414634|ensembl:ENSP00000406280|ensembl:ENSP00000364813|ensembl:ENSP00000372883|ensembl:ENSP00000403345 intact:EBI-373310|uniprotkb:Q9Y4Y8|uniprotkb:Q4W5J5|ensembl:ENSP00000296581|ensembl:ENSP00000420929|ensembl:ENSP00000422392|ensembl:ENSP00000427036|ensembl:ENSP00000497311 psi-mi:lsm2_human(display_long)|uniprotkb:LSM2(gene name)|psi-mi:LSM2(display_short)|uniprotkb:C6orf28(gene name synonym)|uniprotkb:G7B(gene name synonym)|uniprotkb:snRNP core Sm-like protein Sm-x5(gene name synonym)|uniprotkb:Small nuclear ribonuclear protein D homolog(gene name synonym)|uniprotkb:Protein G7b(gene name synonym) psi-mi:lsm6_human(display_long)|uniprotkb:LSM6(gene name)|psi-mi:LSM6(display_short) psi-mi:"MI:0071"(molecular sieving) Scheller et al. (2009) pubmed:19628699|doi:10.1073/pnas.0906413106|imex:IM-14991 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15795409|imex:IM-14991-4|dip:DIP-185535E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_067000.1|ensembl:ENST00000375661(transcript)|ensembl:ENST00000383391(transcript)|ensembl:ENST00000424975(transcript)|ensembl:ENST00000432122(transcript)|ensembl:ENST00000434125(transcript)|ensembl:ENST00000455705(transcript)|go:"GO:0000244"(spliceosomal tri-snRNP complex assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005688"(U6 snRNP)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0120115"(Lsm2-8 complex)|go:"GO:1990726"(Lsm1-7-Pat1 complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR016654(U6 snRNA-associated Sm-like protein LSm2)|mint:Q9Y333|rcsb pdb:3JCR|rcsb pdb:5O9Z|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:7ABG|reactome:R-HSA-430039|reactome:R-HSA-72163|reactome:R-HSA-72165|ensembl:ENSG00000172850(gene)|ensembl:ENSG00000204392(gene)|ensembl:ENSG00000224979(gene)|ensembl:ENSG00000225998(gene)|ensembl:ENSG00000231502(gene)|ensembl:ENSG00000236826(gene)|dip:DIP-31139N refseq:NP_009011.1|ensembl:ENSG00000164167(gene)|ensembl:ENST00000296581(transcript)|ensembl:ENST00000502781(transcript)|ensembl:ENST00000504181(transcript)|ensembl:ENST00000515311(transcript)|ensembl:ENST00000649747(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005688"(U6 snRNP)|go:"GO:0005730"(nucleolus)|go:"GO:0005732"("sno(s)RNA-containing ribonucleoprotein complex")|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0008033"(tRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0030490"(maturation of SSU-rRNA)|go:"GO:0030532"(small nuclear ribonucleoprotein complex)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0120115"(Lsm2-8 complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR016487(Small nuclear ribonucleoprotein SmF)|mint:P62312|rcsb pdb:3JCR|rcsb pdb:5O9Z|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:7ABG|reactome:R-HSA-430039|reactome:R-HSA-72163|refseq:XP_016863161.1|refseq:XP_016863162.1|dip:DIP-31128N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/06 2017/08/10 rogid:lReyYTJxC/WlYg/ekKaqZiNNdVM9606 rogid:knWeW+soIyeLSg0Xbe79er748hE9606 rigid:EBQMeVQ80grv/xpvu9sB+W98lps false - - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q9Y333 uniprotkb:Q9UK45 intact:EBI-347416|uniprotkb:Q6FGG1|ensembl:ENSP00000414006|ensembl:ENSP00000414634|ensembl:ENSP00000406280|ensembl:ENSP00000364813|ensembl:ENSP00000372883|ensembl:ENSP00000403345 intact:EBI-348372|ensembl:ENSP00000252622 psi-mi:lsm2_human(display_long)|uniprotkb:LSM2(gene name)|psi-mi:LSM2(display_short)|uniprotkb:C6orf28(gene name synonym)|uniprotkb:G7B(gene name synonym)|uniprotkb:snRNP core Sm-like protein Sm-x5(gene name synonym)|uniprotkb:Small nuclear ribonuclear protein D homolog(gene name synonym)|uniprotkb:Protein G7b(gene name synonym) psi-mi:lsm7_human(display_long)|uniprotkb:LSM7(gene name)|psi-mi:LSM7(display_short) psi-mi:"MI:0071"(molecular sieving) Scheller et al. (2009) pubmed:19628699|doi:10.1073/pnas.0906413106|imex:IM-14991 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15795409|imex:IM-14991-4|dip:DIP-185535E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_067000.1|ensembl:ENST00000375661(transcript)|ensembl:ENST00000383391(transcript)|ensembl:ENST00000424975(transcript)|ensembl:ENST00000432122(transcript)|ensembl:ENST00000434125(transcript)|ensembl:ENST00000455705(transcript)|go:"GO:0000244"(spliceosomal tri-snRNP complex assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005688"(U6 snRNP)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0120115"(Lsm2-8 complex)|go:"GO:1990726"(Lsm1-7-Pat1 complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR016654(U6 snRNA-associated Sm-like protein LSm2)|mint:Q9Y333|rcsb pdb:3JCR|rcsb pdb:5O9Z|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:7ABG|reactome:R-HSA-430039|reactome:R-HSA-72163|reactome:R-HSA-72165|ensembl:ENSG00000172850(gene)|ensembl:ENSG00000204392(gene)|ensembl:ENSG00000224979(gene)|ensembl:ENSG00000225998(gene)|ensembl:ENSG00000231502(gene)|ensembl:ENSG00000236826(gene)|dip:DIP-31139N refseq:NP_057283.1|interpro:IPR017132(U6 snRNA-associated Sm-like protein LSm7)|interpro:IPR044641|rcsb pdb:3JCR|rcsb pdb:5O9Z|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:7ABG|reactome:R-HSA-430039|reactome:R-HSA-72163|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005829"(cytosol)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071004"(U2-type prespliceosome)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0097526"(spliceosomal tri-snRNP complex)|go:"GO:0120115"(Lsm2-8 complex)|go:"GO:1990726"(Lsm1-7-Pat1 complex)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|ensembl:ENSG00000130332(gene)|ensembl:ENST00000252622(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005688"(U6 snRNP)|dip:DIP-31129N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/06 2017/08/10 rogid:lReyYTJxC/WlYg/ekKaqZiNNdVM9606 rogid:vT1gI3yzYl37cX++CUGdJowAL909606 rigid:EBQMeVQ80grv/xpvu9sB+W98lps false - - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q9Y333 uniprotkb:O95777 intact:EBI-347416|uniprotkb:Q6FGG1|ensembl:ENSP00000414006|ensembl:ENSP00000414634|ensembl:ENSP00000406280|ensembl:ENSP00000364813|ensembl:ENSP00000372883|ensembl:ENSP00000403345 intact:EBI-347779|ensembl:ENSP00000249299 psi-mi:lsm2_human(display_long)|uniprotkb:LSM2(gene name)|psi-mi:LSM2(display_short)|uniprotkb:C6orf28(gene name synonym)|uniprotkb:G7B(gene name synonym)|uniprotkb:snRNP core Sm-like protein Sm-x5(gene name synonym)|uniprotkb:Small nuclear ribonuclear protein D homolog(gene name synonym)|uniprotkb:Protein G7b(gene name synonym) psi-mi:lsm8_human(display_long)|uniprotkb:LSM8(gene name)|psi-mi:LSM8(display_short) psi-mi:"MI:0071"(molecular sieving) Scheller et al. (2009) pubmed:19628699|doi:10.1073/pnas.0906413106|imex:IM-14991 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15795409|imex:IM-14991-4|dip:DIP-185535E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_067000.1|ensembl:ENST00000375661(transcript)|ensembl:ENST00000383391(transcript)|ensembl:ENST00000424975(transcript)|ensembl:ENST00000432122(transcript)|ensembl:ENST00000434125(transcript)|ensembl:ENST00000455705(transcript)|go:"GO:0000244"(spliceosomal tri-snRNP complex assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005688"(U6 snRNP)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0120115"(Lsm2-8 complex)|go:"GO:1990726"(Lsm1-7-Pat1 complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR016654(U6 snRNA-associated Sm-like protein LSm2)|mint:Q9Y333|rcsb pdb:3JCR|rcsb pdb:5O9Z|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:7ABG|reactome:R-HSA-430039|reactome:R-HSA-72163|reactome:R-HSA-72165|ensembl:ENSG00000172850(gene)|ensembl:ENSG00000204392(gene)|ensembl:ENSG00000224979(gene)|ensembl:ENSG00000225998(gene)|ensembl:ENSG00000231502(gene)|ensembl:ENSG00000236826(gene)|dip:DIP-31139N refseq:NP_057284.1|dip:DIP-31195N|ensembl:ENSG00000128534(gene)|ensembl:ENST00000249299(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005688"(U6 snRNP)|go:"GO:0016070"(RNA metabolic process)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0120115"(Lsm2-8 complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR034103|interpro:IPR044642|rcsb pdb:3JCR|rcsb pdb:5O9Z|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:7ABG|reactome:R-HSA-72163 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/06 2017/08/10 rogid:lReyYTJxC/WlYg/ekKaqZiNNdVM9606 rogid:Kyf8IAEIkbe1s2NnqxqGA1o6BbU9606 rigid:EBQMeVQ80grv/xpvu9sB+W98lps false - - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)