#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P70677 uniprotkb:Q60989 intact:EBI-1790419|uniprotkb:O08668|uniprotkb:Q8CHV5|uniprotkb:Q9QWI4|ensembl:ENSMUSP00000091238|ensembl:ENSMUSP00000147767 intact:EBI-517478|uniprotkb:A2BGY6|uniprotkb:O08865|ensembl:ENSMUSP00000026978|ensembl:ENSMUSP00000061074|ensembl:ENSMUSP00000110746|ensembl:ENSMUSP00000110747 psi-mi:casp3_mouse(display_long)|uniprotkb:Casp3(gene name)|psi-mi:Casp3(display_short)|uniprotkb:Cpp32(gene name synonym)|uniprotkb:Apopain(gene name synonym)|uniprotkb:Cysteine protease CPP32(gene name synonym)|uniprotkb:Protein Yama(gene name synonym)|uniprotkb:SREBP cleavage activity 1(gene name synonym)|uniprotkb:LICE(gene name synonym) psi-mi:xiap_mouse(display_long)|uniprotkb:Inhibitor of apoptosis protein 3(gene name synonym)|uniprotkb:X-linked inhibitor of apoptosis protein(gene name synonym)|uniprotkb:IAP homolog A(gene name synonym)|uniprotkb:Xiap(gene name)|psi-mi:Xiap(display_short)|uniprotkb:Aipa(gene name synonym)|uniprotkb:Api3(gene name synonym)|uniprotkb:Miha(gene name synonym)|uniprotkb:Birc4(gene name synonym)|uniprotkb:Baculoviral IAP repeat-containing protein 4(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase XIAP(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Jost et al. (2009) pubmed:19626005|doi:10.1038/nature08229|imex:IM-16341 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15795110|imex:IM-16341-1|dip:DIP-187486E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001271338.1|dip:DIP-44076N|refseq:NP_033940.1|refseq:XP_017168032.1|ensembl:ENSMUSG00000031628(gene)|ensembl:ENSMUST00000093517(transcript)|ensembl:ENSMUST00000211115(transcript)|go:"GO:0001554"(luteolysis)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0002020"(protease binding)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004190"(aspartic-type endopeptidase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005123"(death receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006508"(proteolysis)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007413"(axonal fasciculation)|go:"GO:0007507"(heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007611"(learning or memory)|go:"GO:0008233"(peptidase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0008627"(intrinsic apoptotic signaling pathway in response to osmotic stress)|go:"GO:0009411"(response to UV)|go:"GO:0009611"(response to wounding)|go:"GO:0009749"(response to glucose)|go:"GO:0010033"(response to organic substance)|go:"GO:0010165"(response to X-ray)|go:"GO:0016005"(phospholipase A2 activator activity)|go:"GO:0016485"(protein processing)|go:"GO:0021766"(hippocampus development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0031264"(death-inducing signaling complex)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032025"(response to cobalt ion)|go:"GO:0032355"(response to estradiol)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0034349"(glial cell apoptotic process)|go:"GO:0035094"(response to nicotine)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042060"(wound healing)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043029"(T cell homeostasis)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043200"(response to amino acid)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0046007"(negative regulation of activated T cell proliferation)|go:"GO:0046677"(response to antibiotic)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0051146"(striated muscle cell differentiation)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0061713"(anterior neural tube closure)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0071310"(cellular response to organic substance)|go:"GO:0071887"(leukocyte apoptotic process)|go:"GO:0072734"(cellular response to staurosporine)|go:"GO:0097153"(cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0097194"(execution phase of apoptosis)|go:"GO:0097199"(cysteine-type endopeptidase activity involved in apoptotic signaling pathway)|go:"GO:0097200"(cysteine-type endopeptidase activity involved in execution phase of apoptosis)|go:"GO:1902004"(positive regulation of amyloid-beta formation)|interpro:IPR001309(Peptidase C14, ICE, catalytic subunit p20)|interpro:IPR002138(Peptidase C14, caspase non-catalytic subunit p10)|interpro:IPR002398(Peptidase C14, caspase precursor p45)|interpro:IPR015471(Caspase-7)|interpro:IPR015917(Peptidase C14, caspase precursor p45, core)|interpro:IPR016129(Peptidase C14, ICE, catalytic subunit p20, active site)|interpro:IPR029030|interpro:IPR033139|mint:P70677|reactome:R-MMU-111459|reactome:R-MMU-111465|reactome:R-MMU-111469|reactome:R-MMU-140342|reactome:R-MMU-2028269|reactome:R-MMU-205025|reactome:R-MMU-264870|reactome:R-MMU-351906|reactome:R-MMU-418889|reactome:R-MMU-449836|reactome:R-MMU-5620971 refseq:NP_033818.2|refseq:NP_001288568.1|refseq:NP_001288570.1|refseq:XP_006541488.1|refseq:XP_006541490.1|refseq:XP_017173848.1|refseq:XP_017173849.1|refseq:XP_017173850.1|refseq:XP_017173851.1|refseq:XP_011249279.1|dip:DIP-33721N|ensembl:ENSMUSG00000025860(gene)|ensembl:ENSMUST00000026978(transcript)|ensembl:ENSMUST00000055483(transcript)|ensembl:ENSMUST00000115094(transcript)|ensembl:ENSMUST00000115095(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005876"(spindle microtubule)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097110"(scaffold protein binding)|go:"GO:1902530"(positive regulation of protein linear polyubiquitination)|go:"GO:1990001"(inhibition of cysteine-type endopeptidase activity involved in apoptotic process)|interpro:IPR001370(Proteinase inhibitor I32, inhibitor of apoptosis)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR042579|mint:Q60989|reactome:R-MMU-111459|reactome:R-MMU-111463|reactome:R-MMU-111464|reactome:R-MMU-111469|reactome:R-MMU-3769402|reactome:R-MMU-5357905|reactome:R-MMU-5357956|reactome:R-MMU-5668541|reactome:R-MMU-5675482|reactome:R-MMU-5676594|reactome:R-MMU-8948747|reactome:R-MMU-8948751|reactome:R-MMU-9627069 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse)|taxid:10090(Mus musculus) - 2017/08/06 2017/08/10 rogid:tSqWk4T+WiXomdMHEk4xthh9MZs10090 rogid:nJHDyZvomndsRCl3vfbv33MY/c810090 rigid:bhM59e4uI0nY4urnExs8/GL3x/Q false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)