#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q6XW05	uniprotkb:P60953-2	intact:EBI-15794637	intact:EBI-287394|uniprotkb:P21181-4|ensembl:ENSP00000341072|ensembl:ENSP00000383118|ensembl:ENSP00000497733|ensembl:ENSP00000499457|ensembl:ENSP00000499612	psi-mi:q6xw05_shifl(display_long)|uniprotkb:ipgB2(gene name)|psi-mi:ipgB2(display_short)	psi-mi:p60953-2(display_long)|uniprotkb:CDC42(gene name)|psi-mi:CDC42(display_short)|uniprotkb:G25K GTP-binding protein(gene name synonym)|uniprotkb:Placental(isoform synonym)	psi-mi:"MI:0949"(gdp/gtp exchange assay)	Huang et al. (2009)	pubmed:19620963|doi:10.1038/nsmb.1647|imex:IM-14291	taxid:623(shifl)|taxid:623(Shigella flexneri)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15794647|imex:IM-14291-2|dip:DIP-103112E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR004959(IpaB/EvcA)|dip:DIP-48541N|refseq:WP_005057975.1	intact:EBI-81752(cdc42_human)|ensembl:ENSG00000070831(gene)|ensembl:ENST00000344548(transcript)|ensembl:ENST00000400259(transcript)|ensembl:ENST00000648594(transcript)|ensembl:ENST00000656825(transcript)|ensembl:ENST00000662562(transcript)	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/06	2017/08/10	rogid:Qzl5hPIuYOYF8LcjaPWnrQtLvsM623	rogid:jiYEHWm+9LQyVj0eUGZOBGaajyU9606	rigid:xZ0JJXGQqwJotZjL1yGFM9x9jNI	false	binding-associated region:20-188	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9R8E4	uniprotkb:P60953-2	intact:EBI-15794593|ensemblbacteria:RFQ84566|ensemblbacteria:STI62681|ensemblbacteria:STK11011|ensemblbacteria:AMW43469|ensemblbacteria:APA39888|ensemblbacteria:CTT81500|ensemblbacteria:CTV81086|ensemblbacteria:OOC77435|ensemblbacteria:OWC16445|ensemblbacteria:PAU11010|ensemblbacteria:PJG34646|ensemblbacteria:QCL45817|ensemblbacteria:RCP40747	intact:EBI-287394|uniprotkb:P21181-4|ensembl:ENSP00000341072|ensembl:ENSP00000383118|ensembl:ENSP00000497733|ensembl:ENSP00000499457|ensembl:ENSP00000499612	psi-mi:q9r8e4_ecolx(display_long)|uniprotkb:map(gene name)|psi-mi:map(display_short)|uniprotkb:BFL24_25035(orf name)|uniprotkb:C9E67_00645(orf name)|uniprotkb:DAH23_17530(orf name)|uniprotkb:NCTC13127_00329(orf name)	psi-mi:p60953-2(display_long)|uniprotkb:CDC42(gene name)|psi-mi:CDC42(display_short)|uniprotkb:G25K GTP-binding protein(gene name synonym)|uniprotkb:Placental(isoform synonym)	psi-mi:"MI:0949"(gdp/gtp exchange assay)	Huang et al. (2009)	pubmed:19620963|doi:10.1038/nsmb.1647|imex:IM-14291	taxid:562(ecolx)|taxid:562(Escherichia coli)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15794607|imex:IM-14291-1|dip:DIP-103110E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblbacteria:RFQ84566(transcript)|ensemblbacteria:STI62681(transcript)|ensemblbacteria:STK11011(transcript)|interpro:IPR004959(IpaB/EvcA)|rcsb pdb:3GCG|ensemblbacteria:A6581_10245(gene)|ensemblbacteria:A8G17_12590(gene)|ensemblbacteria:AMW43469(transcript)|ensemblbacteria:APA39888(transcript)|ensemblbacteria:ARC77_15010(gene)|ensemblbacteria:AU473_02850(gene)|ensemblbacteria:BTQ04_20915(gene)|ensemblbacteria:BWP17_19275(gene)|ensemblbacteria:C9E67_00645(gene)|ensemblbacteria:CRE06_16840(gene)|ensemblbacteria:CTT81500(transcript)|ensemblbacteria:CTV81086(transcript)|ensemblbacteria:CVH05_05515(gene)|ensemblbacteria:ERS085383_02502(gene)|ensemblbacteria:ERS085404_04285(gene)|ensemblbacteria:NCTC13127_00329(gene)|ensemblbacteria:NCTC9701_00178(gene)|ensemblbacteria:OOC77435(transcript)|ensemblbacteria:OWC16445(transcript)|ensemblbacteria:PAU11010(transcript)|ensemblbacteria:PJG34646(transcript)|ensemblbacteria:QCL45817(transcript)|ensemblbacteria:RCP40747(transcript)|refseq:WP_000492638.1|dip:DIP-48540N	intact:EBI-81752(cdc42_human)|ensembl:ENSG00000070831(gene)|ensembl:ENST00000344548(transcript)|ensembl:ENST00000400259(transcript)|ensembl:ENST00000648594(transcript)|ensembl:ENST00000656825(transcript)|ensembl:ENST00000662562(transcript)	psi-mi:"MI:0465"(dip)	crc64:4BEDDA6625BD8089	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/06	2017/08/10	rogid:xO5ymWP2ug1VLyxelIaeen+24gM562	rogid:jiYEHWm+9LQyVj0eUGZOBGaajyU9606	rigid:5DXUNGGkMSeLpAC/OKns7fiQ/D8	false	binding-associated region:37-203	mutation decreasing interaction:56-56,52-52,43-43,41-41|mutation disrupting interaction:56-56,52-52,43-43	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9R8E4	uniprotkb:P60953-2	intact:EBI-15794593|ensemblbacteria:RFQ84566|ensemblbacteria:STI62681|ensemblbacteria:STK11011|ensemblbacteria:AMW43469|ensemblbacteria:APA39888|ensemblbacteria:CTT81500|ensemblbacteria:CTV81086|ensemblbacteria:OOC77435|ensemblbacteria:OWC16445|ensemblbacteria:PAU11010|ensemblbacteria:PJG34646|ensemblbacteria:QCL45817|ensemblbacteria:RCP40747	intact:EBI-287394|uniprotkb:P21181-4|ensembl:ENSP00000341072|ensembl:ENSP00000383118|ensembl:ENSP00000497733|ensembl:ENSP00000499457|ensembl:ENSP00000499612	psi-mi:q9r8e4_ecolx(display_long)|uniprotkb:map(gene name)|psi-mi:map(display_short)|uniprotkb:BFL24_25035(orf name)|uniprotkb:C9E67_00645(orf name)|uniprotkb:DAH23_17530(orf name)|uniprotkb:NCTC13127_00329(orf name)	psi-mi:p60953-2(display_long)|uniprotkb:CDC42(gene name)|psi-mi:CDC42(display_short)|uniprotkb:G25K GTP-binding protein(gene name synonym)|uniprotkb:Placental(isoform synonym)	psi-mi:"MI:0096"(pull down)	Huang et al. (2009)	pubmed:19620963|doi:10.1038/nsmb.1647|imex:IM-14291	taxid:562(ecolx)|taxid:562(Escherichia coli)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15794666|imex:IM-14291-3|dip:DIP-103110E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblbacteria:RFQ84566(transcript)|ensemblbacteria:STI62681(transcript)|ensemblbacteria:STK11011(transcript)|interpro:IPR004959(IpaB/EvcA)|rcsb pdb:3GCG|ensemblbacteria:A6581_10245(gene)|ensemblbacteria:A8G17_12590(gene)|ensemblbacteria:AMW43469(transcript)|ensemblbacteria:APA39888(transcript)|ensemblbacteria:ARC77_15010(gene)|ensemblbacteria:AU473_02850(gene)|ensemblbacteria:BTQ04_20915(gene)|ensemblbacteria:BWP17_19275(gene)|ensemblbacteria:C9E67_00645(gene)|ensemblbacteria:CRE06_16840(gene)|ensemblbacteria:CTT81500(transcript)|ensemblbacteria:CTV81086(transcript)|ensemblbacteria:CVH05_05515(gene)|ensemblbacteria:ERS085383_02502(gene)|ensemblbacteria:ERS085404_04285(gene)|ensemblbacteria:NCTC13127_00329(gene)|ensemblbacteria:NCTC9701_00178(gene)|ensemblbacteria:OOC77435(transcript)|ensemblbacteria:OWC16445(transcript)|ensemblbacteria:PAU11010(transcript)|ensemblbacteria:PJG34646(transcript)|ensemblbacteria:QCL45817(transcript)|ensemblbacteria:RCP40747(transcript)|refseq:WP_000492638.1|dip:DIP-48540N	intact:EBI-81752(cdc42_human)|ensembl:ENSG00000070831(gene)|ensembl:ENST00000344548(transcript)|ensembl:ENST00000400259(transcript)|ensembl:ENST00000648594(transcript)|ensembl:ENST00000656825(transcript)|ensembl:ENST00000662562(transcript)	psi-mi:"MI:0465"(dip)	crc64:4BEDDA6625BD8089	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/06	2017/08/10	rogid:xO5ymWP2ug1VLyxelIaeen+24gM562	rogid:jiYEHWm+9LQyVj0eUGZOBGaajyU9606	rigid:5DXUNGGkMSeLpAC/OKns7fiQ/D8	false	binding-associated region:37-203|mutation disrupting interaction:74-74|mutation disrupting interaction:78-78|mutation disrupting interaction:127-127|mutation disrupting interaction:128-128|mutation disrupting interaction:130-130|mutation disrupting interaction:133-133|mutation disrupting interaction:159-159,156-156	glutathione s tranferase tag:n-n	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:P63000-1	uniprotkb:Q6XW05	intact:EBI-7212896|uniprotkb:P15154-1|intact:MINT-124079|ensembl:ENSP00000258737	intact:EBI-15794637	psi-mi:p63000-1(display_long)|uniprotkb:RAC1(gene name)|psi-mi:RAC1(display_short)|uniprotkb:Cell migration-inducing gene 5 protein(gene name synonym)|uniprotkb:Ras-like protein TC25(gene name synonym)|uniprotkb:TC25(gene name synonym)|uniprotkb:p21-Rac1(gene name synonym)|uniprotkb:MIG5(orf name)|uniprotkb:Rac1A(isoform synonym)	psi-mi:q6xw05_shifl(display_long)|uniprotkb:ipgB2(gene name)|psi-mi:ipgB2(display_short)	psi-mi:"MI:0949"(gdp/gtp exchange assay)	Huang et al. (2009)	pubmed:19620963|doi:10.1038/nsmb.1647|imex:IM-14291	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:623(shifl)|taxid:623(Shigella flexneri)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15794813|imex:IM-14291-7|dip:DIP-103114E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-413628(isoform-parent)|ensembl:ENSG00000136238(gene)|ensembl:ENST00000348035(transcript)	interpro:IPR004959(IpaB/EvcA)|dip:DIP-48541N|refseq:WP_005057975.1	psi-mi:"MI:0465"(dip)	comment:mint	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/06	2017/08/10	rogid:8rkYyZSFL5tIfbRNKZgP/UDxD+A9606	rogid:Qzl5hPIuYOYF8LcjaPWnrQtLvsM623	rigid:A/kzxNCKhny1jhSv2cTwcBc/5uw	false	-	binding-associated region:20-188	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q6XW05	uniprotkb:P61586	intact:EBI-15794637	intact:EBI-446668|uniprotkb:P06749|uniprotkb:Q5U024|uniprotkb:Q9UEJ4|uniprotkb:Q53HM4|uniprotkb:Q9UDJ0|ensembl:ENSP00000400175|ensembl:ENSP00000408402|ensembl:ENSP00000503282|ensembl:ENSP00000504180	psi-mi:q6xw05_shifl(display_long)|uniprotkb:ipgB2(gene name)|psi-mi:ipgB2(display_short)	psi-mi:rhoa_human(display_long)|uniprotkb:Rho cDNA clone 12(gene name synonym)|uniprotkb:ARHA(gene name synonym)|uniprotkb:RHO12(gene name synonym)|uniprotkb:RHOA(gene name)|psi-mi:RHOA(display_short)|uniprotkb:ARH12(gene name synonym)	psi-mi:"MI:0949"(gdp/gtp exchange assay)	Huang et al. (2009)	pubmed:19620963|doi:10.1038/nsmb.1647|imex:IM-14291	taxid:623(shifl)|taxid:623(Shigella flexneri)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15794832|imex:IM-14291-8|dip:DIP-103115E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR004959(IpaB/EvcA)|dip:DIP-48541N|refseq:WP_005057975.1	refseq:NP_001655.1|refseq:NP_001300870.1|dip:DIP-29642N|rcsb pdb:3LWN|rcsb pdb:3LXR|rcsb pdb:3MSX|rcsb pdb:3T06|rcsb pdb:4D0N|rcsb pdb:4XH9|rcsb pdb:4XOI|rcsb pdb:4XSG|rcsb pdb:4XSH|rcsb pdb:5A0F|rcsb pdb:5BWM|rcsb pdb:5C2K|rcsb pdb:5C4M|rcsb pdb:5EZ6|rcsb pdb:5FR1|rcsb pdb:5FR2|rcsb pdb:5HPY|rcsb pdb:5IRC|rcsb pdb:5JCP|rcsb pdb:5JHG|rcsb pdb:5JHH|rcsb pdb:5M6X|rcsb pdb:5M70|rcsb pdb:5ZHX|rcsb pdb:6BC0|rcsb pdb:6BCA|rcsb pdb:6BCB|rcsb pdb:6KX2|rcsb pdb:6KX3|rcsb pdb:6R3V|rcsb pdb:6V6M|rcsb pdb:6V6U|rcsb pdb:6V6V|reactome:R-HSA-114604|reactome:R-HSA-193634|reactome:R-HSA-198203|reactome:R-HSA-209563|reactome:R-HSA-2173791|reactome:R-HSA-392451|reactome:R-HSA-3928662|reactome:R-HSA-3928663|reactome:R-HSA-4086400|reactome:R-HSA-416482|reactome:R-HSA-416550|reactome:R-HSA-416572|reactome:R-HSA-4420097|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5625970|reactome:R-HSA-5627117|reactome:R-HSA-5663220|reactome:R-HSA-5666185|reactome:R-HSA-5689896|reactome:R-HSA-6785631|reactome:R-HSA-6798695|reactome:R-HSA-8849471|reactome:R-HSA-8980692|reactome:R-HSA-8985586|reactome:R-HSA-9013106|rcsb pdb:3LW8|ensembl:ENSG00000067560(gene)|ensembl:ENST00000418115(transcript)|ensembl:ENST00000445425(transcript)|ensembl:ENST00000678200(transcript)|ensembl:ENST00000679208(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001822"(kidney development)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005768"(endosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007015"(actin filament organization)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009749"(response to glucose)|go:"GO:0010812"(negative regulation of cell-substrate adhesion)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016477"(cell migration)|go:"GO:0017022"(myosin binding)|go:"GO:0019003"(GDP binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0021795"(cerebral cortex cell migration)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0001998"(angiotensin-mediated vasoconstriction involved in regulation of systemic arterial blood pressure)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030054"(cell junction)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0030496"(midbody)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030865"(cortical cytoskeleton organization)|go:"GO:0031098"(stress-activated protein kinase signaling cascade)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031982"(vesicle)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0033688"(regulation of osteoblast proliferation)|go:"GO:0034329"(cell junction assembly)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0035385"(Roundabout signaling pathway)|go:"GO:0036089"(cleavage furrow formation)|go:"GO:0038027"(apolipoprotein A-I-mediated signaling pathway)|go:"GO:0042476"(odontogenesis)|go:"GO:0042493"|go:"GO:0002363"(alpha-beta T cell lineage commitment)|go:"GO:0042995"(cell projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043149"(stress fiber assembly)|go:"GO:0043197"(dendritic spine)|go:"GO:0043200"(response to amino acid)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0003100"(regulation of systemic arterial blood pressure by endothelin)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0043296"(apical junction complex)|go:"GO:0043297"(apical junction assembly)|go:"GO:0043366"(beta selection)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043542"(endothelial cell migration)|go:"GO:0043931"(ossification involved in bone maturation)|go:"GO:0044319"(wound healing, spreading of cells)|go:"GO:0045198"(establishment of epithelial cell apical/basal polarity)|go:"GO:0045471"(response to ethanol)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046039"(GTP metabolic process)|go:"GO:0046638"(positive regulation of alpha-beta T cell differentiation)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050773"(regulation of dendrite development)|go:"GO:0051022"(Rho GDP-dissociation inhibitor binding)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0060193"(positive regulation of lipase activity)|go:"GO:0061383"(trabecula morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0071803"(positive regulation of podosome assembly)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0071944"(cell periphery)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0090324"(negative regulation of oxidative phosphorylation)|go:"GO:0097498"(endothelial tube lumen extension)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0101003"(ficolin-1-rich granule membrane)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1902766"(skeletal muscle satellite cell migration)|go:"GO:1903427"(negative regulation of reactive oxygen species biosynthetic process)|go:"GO:1903673"(mitotic cleavage furrow formation)|go:"GO:1904695"(positive regulation of vascular associated smooth muscle contraction)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1904753"(negative regulation of vascular associated smooth muscle cell migration)|go:"GO:1904996"(positive regulation of leukocyte adhesion to vascular endothelial cell)|go:"GO:1905274"(regulation of modification of postsynaptic actin cytoskeleton)|go:"GO:1990869"(cellular response to chemokine)|go:"GO:2000177"(regulation of neural precursor cell proliferation)|go:"GO:2000406"(positive regulation of T cell migration)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P61586|rcsb pdb:1A2B|rcsb pdb:1CC0|rcsb pdb:1CXZ|rcsb pdb:1DPF|rcsb pdb:1FTN|rcsb pdb:1KMQ|rcsb pdb:1LB1|rcsb pdb:1OW3|rcsb pdb:1S1C|rcsb pdb:1TX4|rcsb pdb:1X86|rcsb pdb:1XCG|rcsb pdb:2RGN|rcsb pdb:3KZ1|go:"GO:0050919"(negative chemotaxis)	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/06	2017/08/10	rogid:Qzl5hPIuYOYF8LcjaPWnrQtLvsM623	rogid:Yd/tf5PgQoPCemLU4XUUyy0qVAE9606	rigid:iSAtGUA0zxY4B6hZ6zoxd92AdXQ	false	binding-associated region:20-188	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9R8E4	uniprotkb:P60953-2	intact:EBI-15794593|ensemblbacteria:RFQ84566|ensemblbacteria:STI62681|ensemblbacteria:STK11011|ensemblbacteria:AMW43469|ensemblbacteria:APA39888|ensemblbacteria:CTT81500|ensemblbacteria:CTV81086|ensemblbacteria:OOC77435|ensemblbacteria:OWC16445|ensemblbacteria:PAU11010|ensemblbacteria:PJG34646|ensemblbacteria:QCL45817|ensemblbacteria:RCP40747	intact:EBI-287394|uniprotkb:P21181-4|ensembl:ENSP00000341072|ensembl:ENSP00000383118|ensembl:ENSP00000497733|ensembl:ENSP00000499457|ensembl:ENSP00000499612	psi-mi:q9r8e4_ecolx(display_long)|uniprotkb:map(gene name)|psi-mi:map(display_short)|uniprotkb:BFL24_25035(orf name)|uniprotkb:C9E67_00645(orf name)|uniprotkb:DAH23_17530(orf name)|uniprotkb:NCTC13127_00329(orf name)	psi-mi:p60953-2(display_long)|uniprotkb:CDC42(gene name)|psi-mi:CDC42(display_short)|uniprotkb:G25K GTP-binding protein(gene name synonym)|uniprotkb:Placental(isoform synonym)	psi-mi:"MI:0096"(pull down)	Huang et al. (2009)	pubmed:19620963|doi:10.1038/nsmb.1647|imex:IM-14291	taxid:562(ecolx)|taxid:562(Escherichia coli)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15794776|imex:IM-14291-6|dip:DIP-103110E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblbacteria:RFQ84566(transcript)|ensemblbacteria:STI62681(transcript)|ensemblbacteria:STK11011(transcript)|interpro:IPR004959(IpaB/EvcA)|rcsb pdb:3GCG|ensemblbacteria:A6581_10245(gene)|ensemblbacteria:A8G17_12590(gene)|ensemblbacteria:AMW43469(transcript)|ensemblbacteria:APA39888(transcript)|ensemblbacteria:ARC77_15010(gene)|ensemblbacteria:AU473_02850(gene)|ensemblbacteria:BTQ04_20915(gene)|ensemblbacteria:BWP17_19275(gene)|ensemblbacteria:C9E67_00645(gene)|ensemblbacteria:CRE06_16840(gene)|ensemblbacteria:CTT81500(transcript)|ensemblbacteria:CTV81086(transcript)|ensemblbacteria:CVH05_05515(gene)|ensemblbacteria:ERS085383_02502(gene)|ensemblbacteria:ERS085404_04285(gene)|ensemblbacteria:NCTC13127_00329(gene)|ensemblbacteria:NCTC9701_00178(gene)|ensemblbacteria:OOC77435(transcript)|ensemblbacteria:OWC16445(transcript)|ensemblbacteria:PAU11010(transcript)|ensemblbacteria:PJG34646(transcript)|ensemblbacteria:QCL45817(transcript)|ensemblbacteria:RCP40747(transcript)|refseq:WP_000492638.1|dip:DIP-48540N	intact:EBI-81752(cdc42_human)|ensembl:ENSG00000070831(gene)|ensembl:ENST00000344548(transcript)|ensembl:ENST00000400259(transcript)|ensembl:ENST00000648594(transcript)|ensembl:ENST00000656825(transcript)|ensembl:ENST00000662562(transcript)	psi-mi:"MI:0465"(dip)	crc64:4BEDDA6625BD8089	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/06	2017/08/10	rogid:xO5ymWP2ug1VLyxelIaeen+24gM562	rogid:jiYEHWm+9LQyVj0eUGZOBGaajyU9606	rigid:5DXUNGGkMSeLpAC/OKns7fiQ/D8	false	binding-associated region:37-203|glutathione s tranferase tag:n-n	mutation disrupting interaction:56-56|mutation disrupting interaction:56-56,52-52|mutation disrupting interaction:56-56,54-54|mutation disrupting interaction:56-56,52-52,43-43	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:Q6XVY7	uniprotkb:P60953-2	intact:EBI-971574	intact:EBI-287394|uniprotkb:P21181-4|ensembl:ENSP00000341072|ensembl:ENSP00000383118|ensembl:ENSP00000497733|ensembl:ENSP00000499457|ensembl:ENSP00000499612	psi-mi:q6xvy7_shifl(display_long)|uniprotkb:ipgB1(gene name)|psi-mi:ipgB1(display_short)	psi-mi:p60953-2(display_long)|uniprotkb:CDC42(gene name)|psi-mi:CDC42(display_short)|uniprotkb:G25K GTP-binding protein(gene name synonym)|uniprotkb:Placental(isoform synonym)	psi-mi:"MI:0949"(gdp/gtp exchange assay)	Huang et al. (2009)	pubmed:19620963|doi:10.1038/nsmb.1647|imex:IM-14291	taxid:623(shifl)|taxid:623(Shigella flexneri)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15794851|imex:IM-14291-9|dip:DIP-103111E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR004959(IpaB/EvcA)|refseq:WP_001166515.1|dip:DIP-45301N	intact:EBI-81752(cdc42_human)|ensembl:ENSG00000070831(gene)|ensembl:ENST00000344548(transcript)|ensembl:ENST00000400259(transcript)|ensembl:ENST00000648594(transcript)|ensembl:ENST00000656825(transcript)|ensembl:ENST00000662562(transcript)	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/06	2017/08/10	rogid:lgyf74XV+rDOsqhhMiDPyFaueZU623	rogid:jiYEHWm+9LQyVj0eUGZOBGaajyU9606	rigid:ELjt77l7RO5uBdkWzoJPVggCXrQ	false	binding-associated region:46-208	mutation increasing interaction:56-56,52-52,43-43,41-41	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9R8E4	uniprotkb:P60953-2	intact:EBI-15794593|ensemblbacteria:RFQ84566|ensemblbacteria:STI62681|ensemblbacteria:STK11011|ensemblbacteria:AMW43469|ensemblbacteria:APA39888|ensemblbacteria:CTT81500|ensemblbacteria:CTV81086|ensemblbacteria:OOC77435|ensemblbacteria:OWC16445|ensemblbacteria:PAU11010|ensemblbacteria:PJG34646|ensemblbacteria:QCL45817|ensemblbacteria:RCP40747	intact:EBI-287394|uniprotkb:P21181-4|ensembl:ENSP00000341072|ensembl:ENSP00000383118|ensembl:ENSP00000497733|ensembl:ENSP00000499457|ensembl:ENSP00000499612	psi-mi:q9r8e4_ecolx(display_long)|uniprotkb:map(gene name)|psi-mi:map(display_short)|uniprotkb:BFL24_25035(orf name)|uniprotkb:C9E67_00645(orf name)|uniprotkb:DAH23_17530(orf name)|uniprotkb:NCTC13127_00329(orf name)	psi-mi:p60953-2(display_long)|uniprotkb:CDC42(gene name)|psi-mi:CDC42(display_short)|uniprotkb:G25K GTP-binding protein(gene name synonym)|uniprotkb:Placental(isoform synonym)	psi-mi:"MI:0949"(gdp/gtp exchange assay)	Huang et al. (2009)	pubmed:19620963|doi:10.1038/nsmb.1647|imex:IM-14291	taxid:562(ecolx)|taxid:562(Escherichia coli)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15794709|imex:IM-14291-4|dip:DIP-103110E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblbacteria:RFQ84566(transcript)|ensemblbacteria:STI62681(transcript)|ensemblbacteria:STK11011(transcript)|interpro:IPR004959(IpaB/EvcA)|rcsb pdb:3GCG|ensemblbacteria:A6581_10245(gene)|ensemblbacteria:A8G17_12590(gene)|ensemblbacteria:AMW43469(transcript)|ensemblbacteria:APA39888(transcript)|ensemblbacteria:ARC77_15010(gene)|ensemblbacteria:AU473_02850(gene)|ensemblbacteria:BTQ04_20915(gene)|ensemblbacteria:BWP17_19275(gene)|ensemblbacteria:C9E67_00645(gene)|ensemblbacteria:CRE06_16840(gene)|ensemblbacteria:CTT81500(transcript)|ensemblbacteria:CTV81086(transcript)|ensemblbacteria:CVH05_05515(gene)|ensemblbacteria:ERS085383_02502(gene)|ensemblbacteria:ERS085404_04285(gene)|ensemblbacteria:NCTC13127_00329(gene)|ensemblbacteria:NCTC9701_00178(gene)|ensemblbacteria:OOC77435(transcript)|ensemblbacteria:OWC16445(transcript)|ensemblbacteria:PAU11010(transcript)|ensemblbacteria:PJG34646(transcript)|ensemblbacteria:QCL45817(transcript)|ensemblbacteria:RCP40747(transcript)|refseq:WP_000492638.1|dip:DIP-48540N	intact:EBI-81752(cdc42_human)|ensembl:ENSG00000070831(gene)|ensembl:ENST00000344548(transcript)|ensembl:ENST00000400259(transcript)|ensembl:ENST00000648594(transcript)|ensembl:ENST00000656825(transcript)|ensembl:ENST00000662562(transcript)	psi-mi:"MI:0465"(dip)	crc64:4BEDDA6625BD8089	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/06	2017/08/10	rogid:xO5ymWP2ug1VLyxelIaeen+24gM562	rogid:jiYEHWm+9LQyVj0eUGZOBGaajyU9606	rigid:5DXUNGGkMSeLpAC/OKns7fiQ/D8	false	sufficient binding region:127-131|mutation disrupting interaction:74-74|mutation disrupting interaction:78-78|mutation disrupting interaction:127-127|mutation disrupting interaction:128-128|mutation disrupting interaction:130-130|mutation disrupting interaction:133-133|mutation disrupting interaction:159-159,156-156|mutation disrupting interaction:92-92|mutation decreasing interaction:89-89	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9R8E4	uniprotkb:P60953-2	intact:EBI-15794593|ensemblbacteria:RFQ84566|ensemblbacteria:STI62681|ensemblbacteria:STK11011|ensemblbacteria:AMW43469|ensemblbacteria:APA39888|ensemblbacteria:CTT81500|ensemblbacteria:CTV81086|ensemblbacteria:OOC77435|ensemblbacteria:OWC16445|ensemblbacteria:PAU11010|ensemblbacteria:PJG34646|ensemblbacteria:QCL45817|ensemblbacteria:RCP40747	intact:EBI-287394|uniprotkb:P21181-4|ensembl:ENSP00000341072|ensembl:ENSP00000383118|ensembl:ENSP00000497733|ensembl:ENSP00000499457|ensembl:ENSP00000499612	psi-mi:q9r8e4_ecolx(display_long)|uniprotkb:map(gene name)|psi-mi:map(display_short)|uniprotkb:BFL24_25035(orf name)|uniprotkb:C9E67_00645(orf name)|uniprotkb:DAH23_17530(orf name)|uniprotkb:NCTC13127_00329(orf name)	psi-mi:p60953-2(display_long)|uniprotkb:CDC42(gene name)|psi-mi:CDC42(display_short)|uniprotkb:G25K GTP-binding protein(gene name synonym)|uniprotkb:Placental(isoform synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Huang et al. (2009)	pubmed:19620963|doi:10.1038/nsmb.1647|imex:IM-14291	taxid:562(ecolx)|taxid:562(Escherichia coli)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15794757|imex:IM-14291-5|dip:DIP-103110E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblbacteria:RFQ84566(transcript)|ensemblbacteria:STI62681(transcript)|ensemblbacteria:STK11011(transcript)|interpro:IPR004959(IpaB/EvcA)|rcsb pdb:3GCG|ensemblbacteria:A6581_10245(gene)|ensemblbacteria:A8G17_12590(gene)|ensemblbacteria:AMW43469(transcript)|ensemblbacteria:APA39888(transcript)|ensemblbacteria:ARC77_15010(gene)|ensemblbacteria:AU473_02850(gene)|ensemblbacteria:BTQ04_20915(gene)|ensemblbacteria:BWP17_19275(gene)|ensemblbacteria:C9E67_00645(gene)|ensemblbacteria:CRE06_16840(gene)|ensemblbacteria:CTT81500(transcript)|ensemblbacteria:CTV81086(transcript)|ensemblbacteria:CVH05_05515(gene)|ensemblbacteria:ERS085383_02502(gene)|ensemblbacteria:ERS085404_04285(gene)|ensemblbacteria:NCTC13127_00329(gene)|ensemblbacteria:NCTC9701_00178(gene)|ensemblbacteria:OOC77435(transcript)|ensemblbacteria:OWC16445(transcript)|ensemblbacteria:PAU11010(transcript)|ensemblbacteria:PJG34646(transcript)|ensemblbacteria:QCL45817(transcript)|ensemblbacteria:RCP40747(transcript)|refseq:WP_000492638.1|dip:DIP-48540N	intact:EBI-81752(cdc42_human)|ensembl:ENSG00000070831(gene)|ensembl:ENST00000344548(transcript)|ensembl:ENST00000400259(transcript)|ensembl:ENST00000648594(transcript)|ensembl:ENST00000656825(transcript)|ensembl:ENST00000662562(transcript)	psi-mi:"MI:0465"(dip)	crc64:4BEDDA6625BD8089	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/06	2017/08/10	rogid:xO5ymWP2ug1VLyxelIaeen+24gM562	rogid:jiYEHWm+9LQyVj0eUGZOBGaajyU9606	rigid:5DXUNGGkMSeLpAC/OKns7fiQ/D8	false	binding-associated region:37-203	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P63000-1	uniprotkb:Q6XVY7	intact:EBI-7212896|uniprotkb:P15154-1|intact:MINT-124079|ensembl:ENSP00000258737	intact:EBI-971574	psi-mi:p63000-1(display_long)|uniprotkb:RAC1(gene name)|psi-mi:RAC1(display_short)|uniprotkb:Cell migration-inducing gene 5 protein(gene name synonym)|uniprotkb:Ras-like protein TC25(gene name synonym)|uniprotkb:TC25(gene name synonym)|uniprotkb:p21-Rac1(gene name synonym)|uniprotkb:MIG5(orf name)|uniprotkb:Rac1A(isoform synonym)	psi-mi:q6xvy7_shifl(display_long)|uniprotkb:ipgB1(gene name)|psi-mi:ipgB1(display_short)	psi-mi:"MI:0949"(gdp/gtp exchange assay)	Huang et al. (2009)	pubmed:19620963|doi:10.1038/nsmb.1647|imex:IM-14291	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:623(shifl)|taxid:623(Shigella flexneri)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15794876|imex:IM-14291-10|dip:DIP-103113E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-413628(isoform-parent)|ensembl:ENSG00000136238(gene)|ensembl:ENST00000348035(transcript)	interpro:IPR004959(IpaB/EvcA)|refseq:WP_001166515.1|dip:DIP-45301N	psi-mi:"MI:0465"(dip)	comment:mint	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/06	2017/08/10	rogid:8rkYyZSFL5tIfbRNKZgP/UDxD+A9606	rogid:lgyf74XV+rDOsqhhMiDPyFaueZU623	rigid:AS4GAuLnppS3pZ60vf55tiq/Zjo	false	-	binding-associated region:46-208	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)