#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P84092	uniprotkb:P63079	intact:EBI-297693|uniprotkb:P53679|uniprotkb:P20172|ensembl:ENSRNOP00000070202	intact:EBI-6257937|uniprotkb:P15433	psi-mi:ap2m1_rat(display_long)|uniprotkb:Adaptor protein complex AP-2 subunit mu(gene name synonym)|uniprotkb:AP-2 mu chain(gene name synonym)|uniprotkb:Ap2m1(gene name)|psi-mi:Ap2m1(display_short)|uniprotkb:Mu2-adaptin(gene name synonym)|uniprotkb:Plasma membrane adaptor AP-2 50 kDa protein(gene name synonym)|uniprotkb:Clathrin coat assembly protein AP50(gene name synonym)|uniprotkb:Clathrin coat-associated protein AP50(gene name synonym)|uniprotkb:Clathrin assembly protein complex 2 mu medium chain(gene name synonym)|uniprotkb:Adaptor-related protein complex 2 subunit mu(gene name synonym)	psi-mi:gbrb3_rat(display_long)|uniprotkb:Gabrb3(gene name)|psi-mi:Gabrb3(display_short)|uniprotkb:Gabrb-3(gene name synonym)|uniprotkb:"GABA(A) receptor subunit beta-3"(gene name synonym)	psi-mi:"MI:0047"(far western blotting)	Jacob et al. (2009)	pubmed:19617557|doi:10.1073/pnas.0903943106|imex:IM-22461	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15794439|imex:IM-22461-1|dip:DIP-196189E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0098794"(postsynapse)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|interpro:IPR001392(Clathrin adaptor, mu subunit)|interpro:IPR011012(Longin-like)|interpro:IPR018240|interpro:IPR022775|interpro:IPR028565|interpro:IPR036168|interpro:IPR043512|interpro:IPR043532|mint:P84092|rcsb pdb:1BW8|rcsb pdb:1BXX|rcsb pdb:1HES|rcsb pdb:1I31|rcsb pdb:2BP5|rcsb pdb:2JKR|rcsb pdb:2JKT|rcsb pdb:2PR9|rcsb pdb:2VGL|rcsb pdb:2XA7|rcsb pdb:3H85|rcsb pdb:3ML6|rcsb pdb:4UQI|rcsb pdb:5C7Z|rcsb pdb:5FPI|rcsb pdb:5WRK|go:"GO:0097718"(disordered domain specific binding)|rcsb pdb:5WRL|rcsb pdb:5WRM|rcsb pdb:6QH5|rcsb pdb:6QH6|rcsb pdb:6RH6|rcsb pdb:6YAE|rcsb pdb:6YAF|rcsb pdb:6YAH|reactome:R-RNO-177504|reactome:R-RNO-190873|reactome:R-RNO-196025|reactome:R-RNO-2132295|reactome:R-RNO-416993|reactome:R-RNO-437239|reactome:R-RNO-5099900|reactome:R-RNO-5140745|reactome:R-RNO-8856825|reactome:R-RNO-8856828|reactome:R-RNO-8866427|reactome:R-RNO-8964038|ensembl:ENSRNOG00000001709(gene)|ensembl:ENSRNOT00000088821(transcript)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0005048"(signal sequence binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006897"(endocytosis)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0008289"(lipid binding)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030122"(AP-2 adaptor complex)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031623"(receptor internalization)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0043195"(terminal bouton)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0097494"(regulation of vesicle size)|rgd:620135|refseq:NP_446289.1|dip:DIP-29761N	go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007214"(gamma-aminobutyric acid signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007612"(learning)|go:"GO:0007613"(memory)|go:"GO:0009986"(cell surface)|go:"GO:0019098"(reproductive behavior)|go:"GO:0021549"(cerebellum development)|go:"GO:0022851"(GABA-gated chloride ion channel activity)|go:"GO:0030594"(neurotransmitter receptor activity)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0034707"(chloride channel complex)|go:"GO:0035176"(social behavior)|go:"GO:0035612"(AP-2 adaptor complex binding)|go:"GO:0035640"(exploration behavior)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042493"|go:"GO:0042747"(circadian sleep/wake cycle, REM sleep)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043195"(terminal bouton)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0048666"(neuron development)|go:"GO:0050877"(nervous system process)|go:"GO:0051932"(synaptic transmission, GABAergic)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060022"(hard palate development)|go:"GO:0060077"(inhibitory synapse)|go:"GO:0060080"(inhibitory postsynaptic potential)|go:"GO:0060119"(inner ear receptor cell development)|go:"GO:0060384"(innervation)|go:"GO:0061744"(motor behavior)|go:"GO:0071294"(cellular response to zinc ion)|go:"GO:0071420"(cellular response to histamine)|go:"GO:0072347"(response to anesthetic)|go:"GO:0090102"(cochlea development)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099060"(integral component of postsynaptic specialization membrane)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1902476"(chloride transmembrane transport)|go:"GO:1902711"(GABA-A receptor complex)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1904862"(inhibitory synapse assembly)|interpro:IPR002289(Gamma-aminobutyric-acid A receptor, beta subunit)|interpro:IPR006028(Gamma-aminobutyric acid A receptor)|interpro:IPR006029(Neurotransmitter-gated ion-channel transmembrane region)|interpro:IPR006201(Neurotransmitter-gated ion-channel)|interpro:IPR006202(Neurotransmitter-gated ion-channel ligand-binding)|interpro:IPR018000|interpro:IPR036719|interpro:IPR036734|go:"GO:0004890"(GABA-A receptor activity)|go:"GO:0005216"(ion channel activity)|go:"GO:0005254"(chloride channel activity)|rgd:2651|refseq:NP_058761.1|dip:DIP-60770N|reactome:R-RNO-977443	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/06	2017/08/10	rogid:AyJEJTqzHtIRWEnMGBzLQP3H5lA10116	rogid:spsRtfvYAMijH8+WsdGVwHwu+Jo10116	rigid:OBYphZy+Wm3e3aZuxNxE8SkYlhk	false	35s radiolabel:?-?	glutathione s tranferase tag:n-n|mutation decreasing interaction strength:433-433,432-432	-	-	psi-mi:"MI:0833"(autoradiography)	psi-mi:"MI:0833"(autoradiography)