#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P22146	uniprotkb:P06700	intact:EBI-7327|uniprotkb:P23151|uniprotkb:D6W0D4|ensemblfungi:YMR307W	intact:EBI-17219|uniprotkb:D6VRV4|ensemblfungi:YDL042C	psi-mi:gas1_yeast(display_long)|uniprotkb:GAS1(gene name)|psi-mi:GAS1(display_short)|uniprotkb:GGP1(gene name synonym)|uniprotkb:YMR307W(locus name)|uniprotkb:YM9952.09(orf name)|uniprotkb:Glycoprotein GP115(gene name synonym)|uniprotkb:Glycolipid-anchored surface protein 1(gene name synonym)	psi-mi:sir2_yeast(display_long)|uniprotkb:SIR2(gene name)|psi-mi:SIR2(display_short)|uniprotkb:MAR1(gene name synonym)|uniprotkb:YDL042C(locus name)|uniprotkb:D2714(orf name)|uniprotkb:Silent information regulator 2(gene name synonym)|uniprotkb:Regulatory protein SIR2(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Koch et al. (2009)	pubmed:19541632|doi:10.1073/pnas.0900809106|imex:IM-14753	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15789960|imex:IM-14753-1|dip:DIP-103966E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014038.1|sgd:S000004924|mint:P22146|dip:DIP-4390N|ensemblfungi:YMR307W(gene)|ensemblfungi:YMR307W_mRNA(transcript)|go:"GO:0000936"(primary cell septum)|go:"GO:0005576"(extracellular region)|go:"GO:0005618"(cell wall)|go:"GO:0005621"(cellular bud scar)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0006342"|go:"GO:0007568"(aging)|go:"GO:0009277"(fungal-type cell wall)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0030447"(filamentous growth)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034411"("cell wall (1->3)-beta-D-glucan biosynthetic process")|go:"GO:0042124"(1,3-beta-glucanosyltransferase activity)|go:"GO:0045121"(membrane raft)|go:"GO:0071970"("fungal-type cell wall (1->3)-beta-D-glucan biosynthetic process")|go:"GO:1905897"(regulation of response to endoplasmic reticulum stress)|interpro:IPR004886(Glycolipid anchored surface protein GAS1)|interpro:IPR012946(X8)|interpro:IPR017853(Glycoside hydrolase, catalytic core)	refseq:NP_010242.1|sgd:S000002200|go:"GO:0045910"(negative regulation of DNA recombination)|go:"GO:0046872"(metal ion binding)|go:"GO:0046969"("NAD-dependent histone deacetylase activity (H3-K9 specific)")|go:"GO:0046970"("NAD-dependent histone deacetylase activity (H4-K16 specific)")|go:"GO:0070403"(NAD+ binding)|go:"GO:0097695"(establishment of protein-containing complex localization to telomere)|go:"GO:0097752"(regulation of DNA stability)|go:"GO:1904524"(negative regulation of DNA amplification)|interpro:IPR003000(NAD-dependent histone deacetylase, silent information regulator Sir2)|interpro:IPR007654(Protein of unknown function DUF592)|interpro:IPR026590|interpro:IPR029035|rcsb pdb:2HJH|rcsb pdb:4IAO|go:"GO:0034398"(telomere tethering at nuclear periphery)|ensemblfungi:YDL042C_mRNA(transcript)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006325"(chromatin organization)|go:"GO:0006333"(chromatin assembly or disassembly)|go:"GO:0006348"|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0016740"(transferase activity)|ensemblfungi:YDL042C(gene)|go:"GO:0017136"(NAD-dependent histone deacetylase activity)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0030869"(RENT complex)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|dip:DIP-596N|mint:P06700	psi-mi:"MI:0465"(dip)	crc64:D6E39568DCB4C5AE	crc64:52E6937533654586	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/08/06	2017/08/10	rogid:xdhWIDQTiYrW+VOcQpC37njMAZQ559292	rogid:HSrFe/tNeIjMNN3xB+3h7rocgkU559292	rigid:KsyW08RUILbzIKKRrhML2S1K864	false	binding-associated region:163-407	sufficient binding region:244-457	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P22146	uniprotkb:P06700	intact:EBI-7327|uniprotkb:P23151|uniprotkb:D6W0D4|ensemblfungi:YMR307W	intact:EBI-17219|uniprotkb:D6VRV4|ensemblfungi:YDL042C	psi-mi:gas1_yeast(display_long)|uniprotkb:GAS1(gene name)|psi-mi:GAS1(display_short)|uniprotkb:GGP1(gene name synonym)|uniprotkb:YMR307W(locus name)|uniprotkb:YM9952.09(orf name)|uniprotkb:Glycoprotein GP115(gene name synonym)|uniprotkb:Glycolipid-anchored surface protein 1(gene name synonym)	psi-mi:sir2_yeast(display_long)|uniprotkb:SIR2(gene name)|psi-mi:SIR2(display_short)|uniprotkb:MAR1(gene name synonym)|uniprotkb:YDL042C(locus name)|uniprotkb:D2714(orf name)|uniprotkb:Silent information regulator 2(gene name synonym)|uniprotkb:Regulatory protein SIR2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Koch et al. (2009)	pubmed:19541632|doi:10.1073/pnas.0900809106|imex:IM-14753	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15789981|imex:IM-14753-2|dip:DIP-103966E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014038.1|sgd:S000004924|mint:P22146|dip:DIP-4390N|ensemblfungi:YMR307W(gene)|ensemblfungi:YMR307W_mRNA(transcript)|go:"GO:0000936"(primary cell septum)|go:"GO:0005576"(extracellular region)|go:"GO:0005618"(cell wall)|go:"GO:0005621"(cellular bud scar)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0006342"|go:"GO:0007568"(aging)|go:"GO:0009277"(fungal-type cell wall)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0030447"(filamentous growth)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034411"("cell wall (1->3)-beta-D-glucan biosynthetic process")|go:"GO:0042124"(1,3-beta-glucanosyltransferase activity)|go:"GO:0045121"(membrane raft)|go:"GO:0071970"("fungal-type cell wall (1->3)-beta-D-glucan biosynthetic process")|go:"GO:1905897"(regulation of response to endoplasmic reticulum stress)|interpro:IPR004886(Glycolipid anchored surface protein GAS1)|interpro:IPR012946(X8)|interpro:IPR017853(Glycoside hydrolase, catalytic core)	refseq:NP_010242.1|sgd:S000002200|go:"GO:0045910"(negative regulation of DNA recombination)|go:"GO:0046872"(metal ion binding)|go:"GO:0046969"("NAD-dependent histone deacetylase activity (H3-K9 specific)")|go:"GO:0046970"("NAD-dependent histone deacetylase activity (H4-K16 specific)")|go:"GO:0070403"(NAD+ binding)|go:"GO:0097695"(establishment of protein-containing complex localization to telomere)|go:"GO:0097752"(regulation of DNA stability)|go:"GO:1904524"(negative regulation of DNA amplification)|interpro:IPR003000(NAD-dependent histone deacetylase, silent information regulator Sir2)|interpro:IPR007654(Protein of unknown function DUF592)|interpro:IPR026590|interpro:IPR029035|rcsb pdb:2HJH|rcsb pdb:4IAO|go:"GO:0034398"(telomere tethering at nuclear periphery)|ensemblfungi:YDL042C_mRNA(transcript)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006325"(chromatin organization)|go:"GO:0006333"(chromatin assembly or disassembly)|go:"GO:0006348"|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0016740"(transferase activity)|ensemblfungi:YDL042C(gene)|go:"GO:0017136"(NAD-dependent histone deacetylase activity)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0030869"(RENT complex)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|dip:DIP-596N|mint:P06700	psi-mi:"MI:0465"(dip)	crc64:D6E39568DCB4C5AE	crc64:52E6937533654586	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/06	2017/08/10	rogid:xdhWIDQTiYrW+VOcQpC37njMAZQ559292	rogid:HSrFe/tNeIjMNN3xB+3h7rocgkU559292	rigid:KsyW08RUILbzIKKRrhML2S1K864	false	-	glutathione s tranferase tag:n-n	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)