#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P03819 uniprotkb:P03819 intact:EBI-547193|ensemblbacteria:AAC73158|ensemblbacteria:BAB96615 intact:EBI-547193|ensemblbacteria:AAC73158|ensemblbacteria:BAB96615 psi-mi:kefc_ecoli(display_long)|uniprotkb:kefC(gene name)|psi-mi:kefC(display_short)|uniprotkb:trkC(gene name synonym)|uniprotkb:b0047(locus name)|uniprotkb:"K(+)/H(+) antiporter"(gene name synonym)|uniprotkb:JW0046(locus name) psi-mi:kefc_ecoli(display_long)|uniprotkb:kefC(gene name)|psi-mi:kefC(display_short)|uniprotkb:trkC(gene name synonym)|uniprotkb:b0047(locus name)|uniprotkb:"K(+)/H(+) antiporter"(gene name synonym)|uniprotkb:JW0046(locus name) psi-mi:"MI:0404"(comigration in non denaturing gel electrophoresis) Roosild et al. (2009) pubmed:19523906|doi:10.1016/j.str.2009.03.018|imex:IM-11761 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15788638|imex:IM-11761-1|dip:DIP-102531E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_414589.1|refseq:WP_000377098.1|ensemblbacteria:AAC73158(transcript)|ensemblbacteria:b0047(gene)|ensemblbacteria:BAB96615(gene)|ensemblbacteria:BAB96615(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006885"(regulation of pH)|go:"GO:0009636"(response to toxic substance)|go:"GO:0015299"("solute:proton antiporter activity")|go:"GO:0015503"(glutathione-regulated potassium exporter activity)|go:"GO:0015643"(toxic substance binding)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0051595"(response to methylglyoxal)|interpro:IPR003148(Regulator of K+ conductance, N-terminal)|interpro:IPR004771(Potassium efflux system protein)|interpro:IPR006036(Potassium uptake protein TrkA)|interpro:IPR006153(Sodium/hydrogen exchanger)|interpro:IPR023941|interpro:IPR036291|interpro:IPR038770|rcsb pdb:3EYW|rcsb pdb:3L9W|rcsb pdb:3L9X|dip:DIP-10072N refseq:NP_414589.1|refseq:WP_000377098.1|ensemblbacteria:AAC73158(transcript)|ensemblbacteria:b0047(gene)|ensemblbacteria:BAB96615(gene)|ensemblbacteria:BAB96615(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006885"(regulation of pH)|go:"GO:0009636"(response to toxic substance)|go:"GO:0015299"("solute:proton antiporter activity")|go:"GO:0015503"(glutathione-regulated potassium exporter activity)|go:"GO:0015643"(toxic substance binding)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0051595"(response to methylglyoxal)|interpro:IPR003148(Regulator of K+ conductance, N-terminal)|interpro:IPR004771(Potassium efflux system protein)|interpro:IPR006036(Potassium uptake protein TrkA)|interpro:IPR006153(Sodium/hydrogen exchanger)|interpro:IPR023941|interpro:IPR036291|interpro:IPR038770|rcsb pdb:3EYW|rcsb pdb:3L9W|rcsb pdb:3L9X|dip:DIP-10072N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/06 2019/11/25 rogid:vmG7wKk0tKTI0CyOpqf6zTjEhqs83333 rogid:vmG7wKk0tKTI0CyOpqf6zTjEhqs83333 rigid:E/6ODQnuzjBVMTRO/BizdjbQYAw false his tag:n-n his tag:n-n 2 0 psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P0A754 uniprotkb:P03819 intact:EBI-562116|ensemblbacteria:AAC73157|ensemblbacteria:BAB96614|uniprotkb:P31577|uniprotkb:P75629 intact:EBI-547193|ensemblbacteria:AAC73158|ensemblbacteria:BAB96615 psi-mi:keff_ecoli(display_long)|uniprotkb:yabF(gene name synonym)|uniprotkb:kefF(gene name)|psi-mi:kefF(display_short)|uniprotkb:b0046(locus name)|uniprotkb:JW0045(locus name)|uniprotkb:Quinone oxidoreductase KefF(gene name synonym) psi-mi:kefc_ecoli(display_long)|uniprotkb:kefC(gene name)|psi-mi:kefC(display_short)|uniprotkb:trkC(gene name synonym)|uniprotkb:b0047(locus name)|uniprotkb:"K(+)/H(+) antiporter"(gene name synonym)|uniprotkb:JW0046(locus name) psi-mi:"MI:0404"(comigration in non denaturing gel electrophoresis) Roosild et al. (2009) pubmed:19523906|doi:10.1016/j.str.2009.03.018|imex:IM-11761 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-22228199|imex:IM-11761-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0009055"(electron transfer activity)|go:"GO:0010181"(FMN binding)|go:"GO:0032414"(positive regulation of ion transmembrane transporter activity)|go:"GO:0050136"("NADH dehydrogenase (quinone) activity")|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|interpro:IPR003680(Flavodoxin-like fold)|interpro:IPR023948|interpro:IPR029039|rcsb pdb:3EYW|rcsb pdb:3L9W|rcsb pdb:3L9X|ensemblbacteria:AAC73157(transcript)|ensemblbacteria:b0046(gene)|ensemblbacteria:BAB96614(gene)|ensemblbacteria:BAB96614(transcript)|go:"GO:0003955"("NAD(P)H dehydrogenase (quinone) activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0008753"("NADPH dehydrogenase (quinone) activity")|refseq:NP_414588.1|refseq:WP_000600725.1|dip:DIP-35822N refseq:NP_414589.1|refseq:WP_000377098.1|ensemblbacteria:AAC73158(transcript)|ensemblbacteria:b0047(gene)|ensemblbacteria:BAB96615(gene)|ensemblbacteria:BAB96615(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006885"(regulation of pH)|go:"GO:0009636"(response to toxic substance)|go:"GO:0015299"("solute:proton antiporter activity")|go:"GO:0015503"(glutathione-regulated potassium exporter activity)|go:"GO:0015643"(toxic substance binding)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0051595"(response to methylglyoxal)|interpro:IPR003148(Regulator of K+ conductance, N-terminal)|interpro:IPR004771(Potassium efflux system protein)|interpro:IPR006036(Potassium uptake protein TrkA)|interpro:IPR006153(Sodium/hydrogen exchanger)|interpro:IPR023941|interpro:IPR036291|interpro:IPR038770|rcsb pdb:3EYW|rcsb pdb:3L9W|rcsb pdb:3L9X|dip:DIP-10072N psi-mi:"MI:0465"(dip) crc64:F641E3952F4EFC41 - figure legend:Fig. 2B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/06 2019/11/25 rogid:xN2lLwoczHf5XfGuvT70pE8qhR083333 rogid:vmG7wKk0tKTI0CyOpqf6zTjEhqs83333 rigid:zOZUd/8pwqEX9MAxG/vZ2S1F0Wc false - his tag:n-n|sufficient binding region:401-620 2 2 psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P0A754 uniprotkb:P03819 intact:EBI-562116|ensemblbacteria:AAC73157|ensemblbacteria:BAB96614|uniprotkb:P31577|uniprotkb:P75629 intact:EBI-547193|ensemblbacteria:AAC73158|ensemblbacteria:BAB96615 psi-mi:keff_ecoli(display_long)|uniprotkb:yabF(gene name synonym)|uniprotkb:kefF(gene name)|psi-mi:kefF(display_short)|uniprotkb:b0046(locus name)|uniprotkb:JW0045(locus name)|uniprotkb:Quinone oxidoreductase KefF(gene name synonym) psi-mi:kefc_ecoli(display_long)|uniprotkb:kefC(gene name)|psi-mi:kefC(display_short)|uniprotkb:trkC(gene name synonym)|uniprotkb:b0047(locus name)|uniprotkb:"K(+)/H(+) antiporter"(gene name synonym)|uniprotkb:JW0046(locus name) psi-mi:"MI:0114"(x-ray crystallography) Roosild et al. (2009) pubmed:19523906|doi:10.1016/j.str.2009.03.018|imex:IM-11761 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-22228219|wwpdb:3eyw|imex:IM-11761-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0009055"(electron transfer activity)|go:"GO:0010181"(FMN binding)|go:"GO:0032414"(positive regulation of ion transmembrane transporter activity)|go:"GO:0050136"("NADH dehydrogenase (quinone) activity")|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|interpro:IPR003680(Flavodoxin-like fold)|interpro:IPR023948|interpro:IPR029039|rcsb pdb:3EYW|rcsb pdb:3L9W|rcsb pdb:3L9X|ensemblbacteria:AAC73157(transcript)|ensemblbacteria:b0046(gene)|ensemblbacteria:BAB96614(gene)|ensemblbacteria:BAB96614(transcript)|go:"GO:0003955"("NAD(P)H dehydrogenase (quinone) activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0008753"("NADPH dehydrogenase (quinone) activity")|refseq:NP_414588.1|refseq:WP_000600725.1|dip:DIP-35822N refseq:NP_414589.1|refseq:WP_000377098.1|ensemblbacteria:AAC73158(transcript)|ensemblbacteria:b0047(gene)|ensemblbacteria:BAB96615(gene)|ensemblbacteria:BAB96615(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006885"(regulation of pH)|go:"GO:0009636"(response to toxic substance)|go:"GO:0015299"("solute:proton antiporter activity")|go:"GO:0015503"(glutathione-regulated potassium exporter activity)|go:"GO:0015643"(toxic substance binding)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0051595"(response to methylglyoxal)|interpro:IPR003148(Regulator of K+ conductance, N-terminal)|interpro:IPR004771(Potassium efflux system protein)|interpro:IPR006036(Potassium uptake protein TrkA)|interpro:IPR006153(Sodium/hydrogen exchanger)|interpro:IPR023941|interpro:IPR036291|interpro:IPR038770|rcsb pdb:3EYW|rcsb pdb:3L9W|rcsb pdb:3L9X|dip:DIP-10072N psi-mi:"MI:0465"(dip) crc64:F641E3952F4EFC41 - figure legend:Table1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/06 2019/11/25 rogid:xN2lLwoczHf5XfGuvT70pE8qhR083333 rogid:vmG7wKk0tKTI0CyOpqf6zTjEhqs83333 rigid:zOZUd/8pwqEX9MAxG/vZ2S1F0Wc false - his tag:n-n|sufficient binding region:401-620 2 2 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)