#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q9H444 uniprotkb:Q9H444 intact:EBI-749627|uniprotkb:Q53ZD6|uniprotkb:E1P5N4|ensembl:ENSP00000217402 intact:EBI-749627|uniprotkb:Q53ZD6|uniprotkb:E1P5N4|ensembl:ENSP00000217402 psi-mi:chm4b_human(display_long)|uniprotkb:Chromatin-modifying protein 4b(gene name synonym)|uniprotkb:Vacuolar protein sorting-associated protein 32-2(gene name synonym)|uniprotkb:SNF7-2(gene name synonym)|uniprotkb:SNF7 homolog associated with Alix 1(gene name synonym)|uniprotkb:CHMP4B(gene name)|psi-mi:CHMP4B(display_short)|uniprotkb:C20orf178(gene name synonym)|uniprotkb:SHAX1(gene name synonym) psi-mi:chm4b_human(display_long)|uniprotkb:Chromatin-modifying protein 4b(gene name synonym)|uniprotkb:Vacuolar protein sorting-associated protein 32-2(gene name synonym)|uniprotkb:SNF7-2(gene name synonym)|uniprotkb:SNF7 homolog associated with Alix 1(gene name synonym)|uniprotkb:CHMP4B(gene name)|psi-mi:CHMP4B(display_short)|uniprotkb:C20orf178(gene name synonym)|uniprotkb:SHAX1(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Pires et al. (2009) pubmed:19523902|doi:10.1016/j.str.2009.04.007|imex:IM-11760 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15788401|imex:IM-11760-1|dip:DIP-102529E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_789782.1|dip:DIP-29924N|ensembl:ENSG00000101421(gene)|ensembl:ENST00000217402(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000815"(ESCRT III complex)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0006914"(autophagy)|go:"GO:0006997"(nucleus organization)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010458"(exit from mitosis)|go:"GO:0016236"(macroautophagy)|go:"GO:0030117"(membrane coat)|go:"GO:0030496"(midbody)|go:"GO:0031468"(nuclear membrane reassembly)|go:"GO:0031902"(late endosome membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0036438"(maintenance of lens transparency)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0046755"(viral budding)|go:"GO:0046761"(viral budding from plasma membrane)|go:"GO:0051258"(protein polymerization)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0061952"(midbody abscission)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090148"(membrane fission)|go:"GO:0090611"(ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1901673"(regulation of mitotic spindle assembly)|go:"GO:1902902"(negative regulation of autophagosome assembly)|interpro:IPR005024(Snf7)|mint:Q9H444|rcsb pdb:3C3Q|rcsb pdb:3UM3|rcsb pdb:4ABM|rcsb pdb:5MK2|reactome:R-HSA-162588|reactome:R-HSA-1632852|reactome:R-HSA-5620971|reactome:R-HSA-917729|reactome:R-HSA-9610379|reactome:R-HSA-9615710|reactome:R-HSA-9668328|reactome:R-HSA-9679504|reactome:R-HSA-9694676|go:"GO:0010824"(regulation of centrosome duplication) refseq:NP_789782.1|dip:DIP-29924N|ensembl:ENSG00000101421(gene)|ensembl:ENST00000217402(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000815"(ESCRT III complex)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0006914"(autophagy)|go:"GO:0006997"(nucleus organization)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010458"(exit from mitosis)|go:"GO:0016236"(macroautophagy)|go:"GO:0030117"(membrane coat)|go:"GO:0030496"(midbody)|go:"GO:0031468"(nuclear membrane reassembly)|go:"GO:0031902"(late endosome membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0036438"(maintenance of lens transparency)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0046755"(viral budding)|go:"GO:0046761"(viral budding from plasma membrane)|go:"GO:0051258"(protein polymerization)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0061952"(midbody abscission)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090148"(membrane fission)|go:"GO:0090611"(ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1901673"(regulation of mitotic spindle assembly)|go:"GO:1902902"(negative regulation of autophagosome assembly)|interpro:IPR005024(Snf7)|mint:Q9H444|rcsb pdb:3C3Q|rcsb pdb:3UM3|rcsb pdb:4ABM|rcsb pdb:5MK2|reactome:R-HSA-162588|reactome:R-HSA-1632852|reactome:R-HSA-5620971|reactome:R-HSA-917729|reactome:R-HSA-9610379|reactome:R-HSA-9615710|reactome:R-HSA-9668328|reactome:R-HSA-9679504|reactome:R-HSA-9694676|go:"GO:0010824"(regulation of centrosome duplication) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/06 2017/08/10 rogid:hbJvirD5+L7fxzOoWbiP1ky6c9M9606 rogid:hbJvirD5+L7fxzOoWbiP1ky6c9M9606 rigid:2xtv+5+gblYYduLcRirQpKGqsmE false binding-associated region:1-193|his tag:n-n binding-associated region:1-193|his tag:n-n - 0 psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9WU78-1 uniprotkb:Q9WU78-1 intact:EBI-15788421|ensembl:ENSMUSP00000035086 intact:EBI-15788421|ensembl:ENSMUSP00000035086 psi-mi:q9wu78-1(display_long)|uniprotkb:Pdcd6ip(gene name)|psi-mi:Pdcd6ip(display_short)|uniprotkb:Aip1(gene name synonym)|uniprotkb:Alix(gene name synonym)|uniprotkb:ALG-2-interacting protein 1(gene name synonym)|uniprotkb:ALG-2-interacting protein X(gene name synonym)|uniprotkb:E2F1-inducible protein(gene name synonym)|uniprotkb:Eig2(gene name synonym) psi-mi:q9wu78-1(display_long)|uniprotkb:Pdcd6ip(gene name)|psi-mi:Pdcd6ip(display_short)|uniprotkb:Aip1(gene name synonym)|uniprotkb:Alix(gene name synonym)|uniprotkb:ALG-2-interacting protein 1(gene name synonym)|uniprotkb:ALG-2-interacting protein X(gene name synonym)|uniprotkb:E2F1-inducible protein(gene name synonym)|uniprotkb:Eig2(gene name synonym) psi-mi:"MI:0809"(bimolecular fluorescence complementation) Pires et al. (2009) pubmed:19523902|doi:10.1016/j.str.2009.04.007|imex:IM-11760 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15788460|imex:IM-11760-3|dip:DIP-102528E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-641897(isoform-parent)|ensembl:ENSMUSG00000032504(gene)|ensembl:ENSMUST00000035086(transcript) intact:EBI-641897(isoform-parent)|ensembl:ENSMUSG00000032504(gene)|ensembl:ENSMUST00000035086(transcript) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/06 2017/08/10 rogid:mHHuK3MilHPoz71+777a7S2Ijrw10090 rogid:mHHuK3MilHPoz71+777a7S2Ijrw10090 rigid:qfNj2GbpIk9l/7XV7dNPKmI4w/Y false binding-associated region:1-714 binding-associated region:1-714 - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WU78-1 uniprotkb:Q9WU78-1 intact:EBI-15788421|ensembl:ENSMUSP00000035086 intact:EBI-15788421|ensembl:ENSMUSP00000035086 psi-mi:q9wu78-1(display_long)|uniprotkb:Pdcd6ip(gene name)|psi-mi:Pdcd6ip(display_short)|uniprotkb:Aip1(gene name synonym)|uniprotkb:Alix(gene name synonym)|uniprotkb:ALG-2-interacting protein 1(gene name synonym)|uniprotkb:ALG-2-interacting protein X(gene name synonym)|uniprotkb:E2F1-inducible protein(gene name synonym)|uniprotkb:Eig2(gene name synonym) psi-mi:q9wu78-1(display_long)|uniprotkb:Pdcd6ip(gene name)|psi-mi:Pdcd6ip(display_short)|uniprotkb:Aip1(gene name synonym)|uniprotkb:Alix(gene name synonym)|uniprotkb:ALG-2-interacting protein 1(gene name synonym)|uniprotkb:ALG-2-interacting protein X(gene name synonym)|uniprotkb:E2F1-inducible protein(gene name synonym)|uniprotkb:Eig2(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Pires et al. (2009) pubmed:19523902|doi:10.1016/j.str.2009.04.007|imex:IM-11760 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15788434|imex:IM-11760-2|dip:DIP-102528E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-641897(isoform-parent)|ensembl:ENSMUSG00000032504(gene)|ensembl:ENSMUST00000035086(transcript) intact:EBI-641897(isoform-parent)|ensembl:ENSMUSG00000032504(gene)|ensembl:ENSMUST00000035086(transcript) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/06 2017/08/10 rogid:mHHuK3MilHPoz71+777a7S2Ijrw10090 rogid:mHHuK3MilHPoz71+777a7S2Ijrw10090 rigid:qfNj2GbpIk9l/7XV7dNPKmI4w/Y false sufficient binding region:355-714|mutation disrupting interaction:645-645,644-644,643-643,640-640,639-639,638-638 sufficient binding region:355-714|mutation disrupting interaction:645-645,644-644,643-643,640-640,639-639,638-638 - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WU78-1 uniprotkb:Q9WU78-1 intact:EBI-15788421|ensembl:ENSMUSP00000035086 intact:EBI-15788421|ensembl:ENSMUSP00000035086 psi-mi:q9wu78-1(display_long)|uniprotkb:Pdcd6ip(gene name)|psi-mi:Pdcd6ip(display_short)|uniprotkb:Aip1(gene name synonym)|uniprotkb:Alix(gene name synonym)|uniprotkb:ALG-2-interacting protein 1(gene name synonym)|uniprotkb:ALG-2-interacting protein X(gene name synonym)|uniprotkb:E2F1-inducible protein(gene name synonym)|uniprotkb:Eig2(gene name synonym) psi-mi:q9wu78-1(display_long)|uniprotkb:Pdcd6ip(gene name)|psi-mi:Pdcd6ip(display_short)|uniprotkb:Aip1(gene name synonym)|uniprotkb:Alix(gene name synonym)|uniprotkb:ALG-2-interacting protein 1(gene name synonym)|uniprotkb:ALG-2-interacting protein X(gene name synonym)|uniprotkb:E2F1-inducible protein(gene name synonym)|uniprotkb:Eig2(gene name synonym) psi-mi:"MI:0944"(mass spectrometry study of hydrogen/deuterium exchange) Pires et al. (2009) pubmed:19523902|doi:10.1016/j.str.2009.04.007|imex:IM-11760 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15788544|imex:IM-11760-7|dip:DIP-102528E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-641897(isoform-parent)|ensembl:ENSMUSG00000032504(gene)|ensembl:ENSMUST00000035086(transcript) intact:EBI-641897(isoform-parent)|ensembl:ENSMUSG00000032504(gene)|ensembl:ENSMUST00000035086(transcript) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/06 2017/08/10 rogid:mHHuK3MilHPoz71+777a7S2Ijrw10090 rogid:mHHuK3MilHPoz71+777a7S2Ijrw10090 rigid:qfNj2GbpIk9l/7XV7dNPKmI4w/Y false binding-associated region:1-714 binding-associated region:1-714 - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9H444 uniprotkb:Q9WU78-1 intact:EBI-749627|uniprotkb:Q53ZD6|uniprotkb:E1P5N4|ensembl:ENSP00000217402 intact:EBI-15788421|ensembl:ENSMUSP00000035086 psi-mi:chm4b_human(display_long)|uniprotkb:Chromatin-modifying protein 4b(gene name synonym)|uniprotkb:Vacuolar protein sorting-associated protein 32-2(gene name synonym)|uniprotkb:SNF7-2(gene name synonym)|uniprotkb:SNF7 homolog associated with Alix 1(gene name synonym)|uniprotkb:CHMP4B(gene name)|psi-mi:CHMP4B(display_short)|uniprotkb:C20orf178(gene name synonym)|uniprotkb:SHAX1(gene name synonym) psi-mi:q9wu78-1(display_long)|uniprotkb:Pdcd6ip(gene name)|psi-mi:Pdcd6ip(display_short)|uniprotkb:Aip1(gene name synonym)|uniprotkb:Alix(gene name synonym)|uniprotkb:ALG-2-interacting protein 1(gene name synonym)|uniprotkb:ALG-2-interacting protein X(gene name synonym)|uniprotkb:E2F1-inducible protein(gene name synonym)|uniprotkb:Eig2(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Pires et al. (2009) pubmed:19523902|doi:10.1016/j.str.2009.04.007|imex:IM-11760 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15788562|imex:IM-11760-8|dip:DIP-102530E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_789782.1|dip:DIP-29924N|ensembl:ENSG00000101421(gene)|ensembl:ENST00000217402(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000815"(ESCRT III complex)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0006914"(autophagy)|go:"GO:0006997"(nucleus organization)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010458"(exit from mitosis)|go:"GO:0016236"(macroautophagy)|go:"GO:0030117"(membrane coat)|go:"GO:0030496"(midbody)|go:"GO:0031468"(nuclear membrane reassembly)|go:"GO:0031902"(late endosome membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0036438"(maintenance of lens transparency)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0046755"(viral budding)|go:"GO:0046761"(viral budding from plasma membrane)|go:"GO:0051258"(protein polymerization)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0061952"(midbody abscission)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090148"(membrane fission)|go:"GO:0090611"(ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1901673"(regulation of mitotic spindle assembly)|go:"GO:1902902"(negative regulation of autophagosome assembly)|interpro:IPR005024(Snf7)|mint:Q9H444|rcsb pdb:3C3Q|rcsb pdb:3UM3|rcsb pdb:4ABM|rcsb pdb:5MK2|reactome:R-HSA-162588|reactome:R-HSA-1632852|reactome:R-HSA-5620971|reactome:R-HSA-917729|reactome:R-HSA-9610379|reactome:R-HSA-9615710|reactome:R-HSA-9668328|reactome:R-HSA-9679504|reactome:R-HSA-9694676|go:"GO:0010824"(regulation of centrosome duplication) intact:EBI-641897(isoform-parent)|ensembl:ENSMUSG00000032504(gene)|ensembl:ENSMUST00000035086(transcript) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/06 2017/08/10 rogid:hbJvirD5+L7fxzOoWbiP1ky6c9M9606 rogid:mHHuK3MilHPoz71+777a7S2Ijrw10090 rigid:TAeg7xq0XVBbMF+L+uEiBT80+S8 false binding-associated region:204-224,1-175|his tag:n-n binding-associated region:1-714 - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9WU78-1 uniprotkb:Q9WU78-1 intact:EBI-15788421|ensembl:ENSMUSP00000035086 intact:EBI-15788421|ensembl:ENSMUSP00000035086 psi-mi:q9wu78-1(display_long)|uniprotkb:Pdcd6ip(gene name)|psi-mi:Pdcd6ip(display_short)|uniprotkb:Aip1(gene name synonym)|uniprotkb:Alix(gene name synonym)|uniprotkb:ALG-2-interacting protein 1(gene name synonym)|uniprotkb:ALG-2-interacting protein X(gene name synonym)|uniprotkb:E2F1-inducible protein(gene name synonym)|uniprotkb:Eig2(gene name synonym) psi-mi:q9wu78-1(display_long)|uniprotkb:Pdcd6ip(gene name)|psi-mi:Pdcd6ip(display_short)|uniprotkb:Aip1(gene name synonym)|uniprotkb:Alix(gene name synonym)|uniprotkb:ALG-2-interacting protein 1(gene name synonym)|uniprotkb:ALG-2-interacting protein X(gene name synonym)|uniprotkb:E2F1-inducible protein(gene name synonym)|uniprotkb:Eig2(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Pires et al. (2009) pubmed:19523902|doi:10.1016/j.str.2009.04.007|imex:IM-11760 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15788586|imex:IM-11760-9|dip:DIP-102528E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-641897(isoform-parent)|ensembl:ENSMUSG00000032504(gene)|ensembl:ENSMUST00000035086(transcript) intact:EBI-641897(isoform-parent)|ensembl:ENSMUSG00000032504(gene)|ensembl:ENSMUST00000035086(transcript) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/06 2017/08/10 rogid:mHHuK3MilHPoz71+777a7S2Ijrw10090 rogid:mHHuK3MilHPoz71+777a7S2Ijrw10090 rigid:qfNj2GbpIk9l/7XV7dNPKmI4w/Y false binding-associated region:1-714 binding-associated region:1-714 - 0 psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9WU78-1 uniprotkb:Q9WU78-1 intact:EBI-15788421|ensembl:ENSMUSP00000035086 intact:EBI-15788421|ensembl:ENSMUSP00000035086 psi-mi:q9wu78-1(display_long)|uniprotkb:Pdcd6ip(gene name)|psi-mi:Pdcd6ip(display_short)|uniprotkb:Aip1(gene name synonym)|uniprotkb:Alix(gene name synonym)|uniprotkb:ALG-2-interacting protein 1(gene name synonym)|uniprotkb:ALG-2-interacting protein X(gene name synonym)|uniprotkb:E2F1-inducible protein(gene name synonym)|uniprotkb:Eig2(gene name synonym) psi-mi:q9wu78-1(display_long)|uniprotkb:Pdcd6ip(gene name)|psi-mi:Pdcd6ip(display_short)|uniprotkb:Aip1(gene name synonym)|uniprotkb:Alix(gene name synonym)|uniprotkb:ALG-2-interacting protein 1(gene name synonym)|uniprotkb:ALG-2-interacting protein X(gene name synonym)|uniprotkb:E2F1-inducible protein(gene name synonym)|uniprotkb:Eig2(gene name synonym) psi-mi:"MI:0067"(light scattering) Pires et al. (2009) pubmed:19523902|doi:10.1016/j.str.2009.04.007|imex:IM-11760 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15788518|imex:IM-11760-6|dip:DIP-102528E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-641897(isoform-parent)|ensembl:ENSMUSG00000032504(gene)|ensembl:ENSMUST00000035086(transcript) intact:EBI-641897(isoform-parent)|ensembl:ENSMUSG00000032504(gene)|ensembl:ENSMUST00000035086(transcript) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/06 2017/08/10 rogid:mHHuK3MilHPoz71+777a7S2Ijrw10090 rogid:mHHuK3MilHPoz71+777a7S2Ijrw10090 rigid:qfNj2GbpIk9l/7XV7dNPKmI4w/Y false sufficient binding region:355-714|mutation disrupting interaction:645-645,644-644,643-643,640-640,639-639,638-638 sufficient binding region:355-714|mutation disrupting interaction:645-645,644-644,643-643,640-640,639-639,638-638 - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9H444 uniprotkb:Q9WU78-1 intact:EBI-749627|uniprotkb:Q53ZD6|uniprotkb:E1P5N4|ensembl:ENSP00000217402 intact:EBI-15788421|ensembl:ENSMUSP00000035086 psi-mi:chm4b_human(display_long)|uniprotkb:Chromatin-modifying protein 4b(gene name synonym)|uniprotkb:Vacuolar protein sorting-associated protein 32-2(gene name synonym)|uniprotkb:SNF7-2(gene name synonym)|uniprotkb:SNF7 homolog associated with Alix 1(gene name synonym)|uniprotkb:CHMP4B(gene name)|psi-mi:CHMP4B(display_short)|uniprotkb:C20orf178(gene name synonym)|uniprotkb:SHAX1(gene name synonym) psi-mi:q9wu78-1(display_long)|uniprotkb:Pdcd6ip(gene name)|psi-mi:Pdcd6ip(display_short)|uniprotkb:Aip1(gene name synonym)|uniprotkb:Alix(gene name synonym)|uniprotkb:ALG-2-interacting protein 1(gene name synonym)|uniprotkb:ALG-2-interacting protein X(gene name synonym)|uniprotkb:E2F1-inducible protein(gene name synonym)|uniprotkb:Eig2(gene name synonym) psi-mi:"MI:0410"(3D electron microscopy) Pires et al. (2009) pubmed:19523902|doi:10.1016/j.str.2009.04.007|imex:IM-11760 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15788496|imex:IM-11760-5|dip:DIP-102530E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_789782.1|dip:DIP-29924N|ensembl:ENSG00000101421(gene)|ensembl:ENST00000217402(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000815"(ESCRT III complex)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0006914"(autophagy)|go:"GO:0006997"(nucleus organization)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010458"(exit from mitosis)|go:"GO:0016236"(macroautophagy)|go:"GO:0030117"(membrane coat)|go:"GO:0030496"(midbody)|go:"GO:0031468"(nuclear membrane reassembly)|go:"GO:0031902"(late endosome membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0036438"(maintenance of lens transparency)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0046755"(viral budding)|go:"GO:0046761"(viral budding from plasma membrane)|go:"GO:0051258"(protein polymerization)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0061952"(midbody abscission)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090148"(membrane fission)|go:"GO:0090611"(ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1901673"(regulation of mitotic spindle assembly)|go:"GO:1902902"(negative regulation of autophagosome assembly)|interpro:IPR005024(Snf7)|mint:Q9H444|rcsb pdb:3C3Q|rcsb pdb:3UM3|rcsb pdb:4ABM|rcsb pdb:5MK2|reactome:R-HSA-162588|reactome:R-HSA-1632852|reactome:R-HSA-5620971|reactome:R-HSA-917729|reactome:R-HSA-9610379|reactome:R-HSA-9615710|reactome:R-HSA-9668328|reactome:R-HSA-9679504|reactome:R-HSA-9694676|go:"GO:0010824"(regulation of centrosome duplication) intact:EBI-641897(isoform-parent)|ensembl:ENSMUSG00000032504(gene)|ensembl:ENSMUST00000035086(transcript) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/06 2017/08/10 rogid:hbJvirD5+L7fxzOoWbiP1ky6c9M9606 rogid:mHHuK3MilHPoz71+777a7S2Ijrw10090 rigid:TAeg7xq0XVBbMF+L+uEiBT80+S8 false binding-associated region:204-224,1-175 binding-associated region:1-714 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9H444 uniprotkb:Q9H444 intact:EBI-749627|uniprotkb:Q53ZD6|uniprotkb:E1P5N4|ensembl:ENSP00000217402 intact:EBI-749627|uniprotkb:Q53ZD6|uniprotkb:E1P5N4|ensembl:ENSP00000217402 psi-mi:chm4b_human(display_long)|uniprotkb:Chromatin-modifying protein 4b(gene name synonym)|uniprotkb:Vacuolar protein sorting-associated protein 32-2(gene name synonym)|uniprotkb:SNF7-2(gene name synonym)|uniprotkb:SNF7 homolog associated with Alix 1(gene name synonym)|uniprotkb:CHMP4B(gene name)|psi-mi:CHMP4B(display_short)|uniprotkb:C20orf178(gene name synonym)|uniprotkb:SHAX1(gene name synonym) psi-mi:chm4b_human(display_long)|uniprotkb:Chromatin-modifying protein 4b(gene name synonym)|uniprotkb:Vacuolar protein sorting-associated protein 32-2(gene name synonym)|uniprotkb:SNF7-2(gene name synonym)|uniprotkb:SNF7 homolog associated with Alix 1(gene name synonym)|uniprotkb:CHMP4B(gene name)|psi-mi:CHMP4B(display_short)|uniprotkb:C20orf178(gene name synonym)|uniprotkb:SHAX1(gene name synonym) psi-mi:"MI:0410"(3D electron microscopy) Pires et al. (2009) pubmed:19523902|doi:10.1016/j.str.2009.04.007|imex:IM-11760 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15788478|imex:IM-11760-4|dip:DIP-102529E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_789782.1|dip:DIP-29924N|ensembl:ENSG00000101421(gene)|ensembl:ENST00000217402(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000815"(ESCRT III complex)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0006914"(autophagy)|go:"GO:0006997"(nucleus organization)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010458"(exit from mitosis)|go:"GO:0016236"(macroautophagy)|go:"GO:0030117"(membrane coat)|go:"GO:0030496"(midbody)|go:"GO:0031468"(nuclear membrane reassembly)|go:"GO:0031902"(late endosome membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0036438"(maintenance of lens transparency)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0046755"(viral budding)|go:"GO:0046761"(viral budding from plasma membrane)|go:"GO:0051258"(protein polymerization)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0061952"(midbody abscission)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090148"(membrane fission)|go:"GO:0090611"(ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1901673"(regulation of mitotic spindle assembly)|go:"GO:1902902"(negative regulation of autophagosome assembly)|interpro:IPR005024(Snf7)|mint:Q9H444|rcsb pdb:3C3Q|rcsb pdb:3UM3|rcsb pdb:4ABM|rcsb pdb:5MK2|reactome:R-HSA-162588|reactome:R-HSA-1632852|reactome:R-HSA-5620971|reactome:R-HSA-917729|reactome:R-HSA-9610379|reactome:R-HSA-9615710|reactome:R-HSA-9668328|reactome:R-HSA-9679504|reactome:R-HSA-9694676|go:"GO:0010824"(regulation of centrosome duplication) refseq:NP_789782.1|dip:DIP-29924N|ensembl:ENSG00000101421(gene)|ensembl:ENST00000217402(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000815"(ESCRT III complex)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0006914"(autophagy)|go:"GO:0006997"(nucleus organization)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010458"(exit from mitosis)|go:"GO:0016236"(macroautophagy)|go:"GO:0030117"(membrane coat)|go:"GO:0030496"(midbody)|go:"GO:0031468"(nuclear membrane reassembly)|go:"GO:0031902"(late endosome membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0036438"(maintenance of lens transparency)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0046755"(viral budding)|go:"GO:0046761"(viral budding from plasma membrane)|go:"GO:0051258"(protein polymerization)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0061952"(midbody abscission)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090148"(membrane fission)|go:"GO:0090611"(ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1901673"(regulation of mitotic spindle assembly)|go:"GO:1902902"(negative regulation of autophagosome assembly)|interpro:IPR005024(Snf7)|mint:Q9H444|rcsb pdb:3C3Q|rcsb pdb:3UM3|rcsb pdb:4ABM|rcsb pdb:5MK2|reactome:R-HSA-162588|reactome:R-HSA-1632852|reactome:R-HSA-5620971|reactome:R-HSA-917729|reactome:R-HSA-9610379|reactome:R-HSA-9615710|reactome:R-HSA-9668328|reactome:R-HSA-9679504|reactome:R-HSA-9694676|go:"GO:0010824"(regulation of centrosome duplication) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/06 2017/08/10 rogid:hbJvirD5+L7fxzOoWbiP1ky6c9M9606 rogid:hbJvirD5+L7fxzOoWbiP1ky6c9M9606 rigid:2xtv+5+gblYYduLcRirQpKGqsmE false binding-associated region:1-193 binding-associated region:1-193 - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9WU78-1 uniprotkb:Q9WU78-1 intact:EBI-15788421|ensembl:ENSMUSP00000035086 intact:EBI-15788421|ensembl:ENSMUSP00000035086 psi-mi:q9wu78-1(display_long)|uniprotkb:Pdcd6ip(gene name)|psi-mi:Pdcd6ip(display_short)|uniprotkb:Aip1(gene name synonym)|uniprotkb:Alix(gene name synonym)|uniprotkb:ALG-2-interacting protein 1(gene name synonym)|uniprotkb:ALG-2-interacting protein X(gene name synonym)|uniprotkb:E2F1-inducible protein(gene name synonym)|uniprotkb:Eig2(gene name synonym) psi-mi:q9wu78-1(display_long)|uniprotkb:Pdcd6ip(gene name)|psi-mi:Pdcd6ip(display_short)|uniprotkb:Aip1(gene name synonym)|uniprotkb:Alix(gene name synonym)|uniprotkb:ALG-2-interacting protein 1(gene name synonym)|uniprotkb:ALG-2-interacting protein X(gene name synonym)|uniprotkb:E2F1-inducible protein(gene name synonym)|uniprotkb:Eig2(gene name synonym) psi-mi:"MI:0826"(x ray scattering) Pires et al. (2009) pubmed:19523902|doi:10.1016/j.str.2009.04.007|imex:IM-11760 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15788604|imex:IM-11760-10|dip:DIP-102528E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-641897(isoform-parent)|ensembl:ENSMUSG00000032504(gene)|ensembl:ENSMUST00000035086(transcript) intact:EBI-641897(isoform-parent)|ensembl:ENSMUSG00000032504(gene)|ensembl:ENSMUST00000035086(transcript) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/06 2017/08/10 rogid:mHHuK3MilHPoz71+777a7S2Ijrw10090 rogid:mHHuK3MilHPoz71+777a7S2Ijrw10090 rigid:qfNj2GbpIk9l/7XV7dNPKmI4w/Y false sufficient binding region:355-714|mutation disrupting interaction:645-645,644-644,643-643,640-640,639-639,638-638 sufficient binding region:355-714|mutation disrupting interaction:645-645,644-644,643-643,640-640,639-639,638-638 - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)