#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P12866	uniprotkb:P40318	intact:EBI-18383|uniprotkb:D6VWZ4|ensemblfungi:YKL209C	intact:EBI-18208|uniprotkb:D6VVQ1|ensemblfungi:YIL030C	psi-mi:ste6_yeast(display_long)|uniprotkb:STE6(gene name)|psi-mi:STE6(display_short)|uniprotkb:Multiple drug resistance protein homolog(gene name synonym)|uniprotkb:P-glycoprotein(gene name synonym)|uniprotkb:Mating factor A secretion protein STE6(gene name synonym)|uniprotkb:YKL209C(locus name)	psi-mi:doa10_yeast(display_long)|uniprotkb:SSM4(gene name)|psi-mi:SSM4(display_short)|uniprotkb:DOA10(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase DOA10(gene name synonym)|uniprotkb:YI3299.01C(orf name)|uniprotkb:YI9905.18C(orf name)|uniprotkb:YIL030C(locus name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Adle et al. (2009)	pubmed:19515821|doi:10.1073/pnas.0812114106|imex:IM-14751	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15787551|imex:IM-14751-1|dip:DIP-68270E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012713.1|sgd:S000001692|ensemblfungi:YKL209C(gene)|ensemblfungi:YKL209C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000770"(peptide pheromone export)|go:"GO:0005524"(ATP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0015440"(ABC-type peptide transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019236"(response to pheromone)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0043332"(mating projection tip)|go:"GO:0055085"(transmembrane transport)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR017871|interpro:IPR027417|interpro:IPR030246|interpro:IPR036640|reactome:R-SCE-382556|dip:DIP-2594N|mint:P12866	sgd:S000001292|ensemblfungi:YIL030C(gene)|ensemblfungi:YIL030C_mRNA(transcript)|go:"GO:0000837"(Doa10p ubiquitin ligase complex)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR011016(Zinc finger, variant RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|rcsb pdb:2M6M|refseq:NP_012234.3|dip:DIP-7286N|mint:P40318	psi-mi:"MI:0465"(dip)	crc64:B240B7E51D9680D5	crc64:3EDFF7F9D90A0C8C	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/08/06	2017/08/10	rogid:G3ZhCo+dInWlxMbhtTagcCyAbXI559292	rogid:/rWhsEcXbPYVDvgXwErWb4rlhlE559292	rigid:TrzANZWS0vzXWR5Mj6pb5w9OusU	false	ha tag:n-n	myc tag:c-c	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
intact:EBI-19797	uniprotkb:P38360	dip:DIP-1549N|uniprotkb:P04838|uniprotkb:Q6LA96	intact:EBI-3340|uniprotkb:D6VQT9|ensemblfungi:YBR295W	psi-mi:ubiq_yeast(display_short)|psi-mi:EBI-19797(display_long)|uniprotkb:UBI1(gene name)|psi-mi:UBI1(display_short)|uniprotkb:RPL40A(gene name synonym)|uniprotkb:YIL148W(locus name)|uniprotkb:UBI2(gene name)|psi-mi:UBI2(display_short)|uniprotkb:RPL40B(gene name synonym)|uniprotkb:YKR094C(locus name)|uniprotkb:UBI3(gene name)|psi-mi:UBI3(display_short)|uniprotkb:RPS31(gene name synonym)|uniprotkb:YLR167W(locus name)|uniprotkb:L9470.14(orf name)|uniprotkb:UBI4(gene name)|psi-mi:UBI4(display_short)|uniprotkb:SCD2(gene name synonym)|uniprotkb:YLL039C(locus name)	psi-mi:atu1_yeast(display_long)|uniprotkb:CAD2(gene name synonym)|uniprotkb:PCA1(gene name)|psi-mi:PCA1(display_short)|uniprotkb:YBR295W(locus name)|uniprotkb:YBR2112(orf name)|uniprotkb:PAY2(gene name synonym)|uniprotkb:Cadmium resistance protein 2(gene name synonym)|uniprotkb:Cadmium-translocating P-type ATPase(gene name synonym)|uniprotkb:"Cd(2+)-exporting ATPase"(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Adle et al. (2009)	pubmed:19515821|doi:10.1073/pnas.0812114106|imex:IM-14751	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15787572|imex:IM-14751-2|dip:DIP-103877E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000001410(RPL40A)|sgd:S000001802(RPL40B)|sgd:S000004157(RPS31)|sgd:S000003962(UBI4)|uniprotkb:P61864(see-also)|refseq:NP_012118.1|refseq:NP_013020.1|refseq:NP_013061.1|refseq:NP_013268.1|ensembl:YIL148W|ensembl:YKR094C|ensembl:YLR167W|go:"GO:0005515"(protein binding)|interpro:IPR000626(Ubiquitin)|cygd:YLR167w|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0005739"(mitochondrion)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0006412"(translation)|ensembl:YLL039C|rcsb pdb:1OTR|rcsb pdb:1Q0W|rcsb pdb:1WR1|rcsb pdb:1ZW7|rcsb pdb:2G3Q|go:"GO:0005634"(nucleus)|go:"GO:0006281"(DNA repair)|cygd:YIL148w|cygd:YKR094c|cygd:YLL039c|rcsb pdb:2JT4|rcsb pdb:2JWZ|rcsb pdb:3CMM|interpro:IPR019954|interpro:IPR019956|interpro:IPR019955|rcsb pdb:3L0W|rcsb pdb:3L10|rcsb pdb:3MHS|rcsb pdb:2KDI	refseq:NP_009854.2|sgd:S000000499|dip:DIP-6641N|ensemblfungi:YBR295W(gene)|ensemblfungi:YBR295W_mRNA(transcript)|go:"GO:0005507"(copper ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005839"(proteasome core complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006875"(cellular metal ion homeostasis)|go:"GO:0008551"(P-type cadmium transporter activity)|go:"GO:0015691"(cadmium ion transport)|go:"GO:0035434"(copper ion transmembrane transport)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0055085"(transmembrane transport)|go:"GO:0070628"(proteasome binding)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR006121(Heavy metal transport/detoxification protein)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR027256|interpro:IPR036163|interpro:IPR036412|interpro:IPR044492	psi-mi:"MI:0465"(dip)	no-uniprot-update:obsolete protein	crc64:E4DCAFB23AA1F138	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/08/06	2017/08/15	rogid:sUFDb7kGedoC/k80bI4sjOaMLHs4932	rogid:OwqNOMGiIyKirxLPaaoEuQZnKcs559292	rigid:c5/LSjKAbyubD73pSKx+2mgNEGg	false	-	ha tag:n-n	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P40318	uniprotkb:P38360	intact:EBI-18208|uniprotkb:D6VVQ1|ensemblfungi:YIL030C	intact:EBI-3340|uniprotkb:D6VQT9|ensemblfungi:YBR295W	psi-mi:doa10_yeast(display_long)|uniprotkb:SSM4(gene name)|psi-mi:SSM4(display_short)|uniprotkb:DOA10(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase DOA10(gene name synonym)|uniprotkb:YI3299.01C(orf name)|uniprotkb:YI9905.18C(orf name)|uniprotkb:YIL030C(locus name)	psi-mi:atu1_yeast(display_long)|uniprotkb:CAD2(gene name synonym)|uniprotkb:PCA1(gene name)|psi-mi:PCA1(display_short)|uniprotkb:YBR295W(locus name)|uniprotkb:YBR2112(orf name)|uniprotkb:PAY2(gene name synonym)|uniprotkb:Cadmium resistance protein 2(gene name synonym)|uniprotkb:Cadmium-translocating P-type ATPase(gene name synonym)|uniprotkb:"Cd(2+)-exporting ATPase"(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Adle et al. (2009)	pubmed:19515821|doi:10.1073/pnas.0812114106|imex:IM-14751	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15787591|imex:IM-14751-3|dip:DIP-103878E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000001292|ensemblfungi:YIL030C(gene)|ensemblfungi:YIL030C_mRNA(transcript)|go:"GO:0000837"(Doa10p ubiquitin ligase complex)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR011016(Zinc finger, variant RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|rcsb pdb:2M6M|refseq:NP_012234.3|dip:DIP-7286N|mint:P40318	refseq:NP_009854.2|sgd:S000000499|dip:DIP-6641N|ensemblfungi:YBR295W(gene)|ensemblfungi:YBR295W_mRNA(transcript)|go:"GO:0005507"(copper ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005839"(proteasome core complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006875"(cellular metal ion homeostasis)|go:"GO:0008551"(P-type cadmium transporter activity)|go:"GO:0015691"(cadmium ion transport)|go:"GO:0035434"(copper ion transmembrane transport)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0055085"(transmembrane transport)|go:"GO:0070628"(proteasome binding)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR006121(Heavy metal transport/detoxification protein)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR027256|interpro:IPR036163|interpro:IPR036412|interpro:IPR044492	psi-mi:"MI:0465"(dip)	crc64:3EDFF7F9D90A0C8C	crc64:E4DCAFB23AA1F138	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/08/06	2017/08/10	rogid:/rWhsEcXbPYVDvgXwErWb4rlhlE559292	rogid:OwqNOMGiIyKirxLPaaoEuQZnKcs559292	rigid:Wtlvyq2UMc4lFoZoey1xW/F+utM	false	myc tag:c-c	ha tag:n-n|sufficient binding region:1-392	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)