#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P33112	uniprotkb:P33113	intact:EBI-15786652	intact:EBI-15786635	psi-mi:spar_baciu(display_long)|uniprotkb:spaR(gene name)|psi-mi:spaR(display_short)|uniprotkb:Subtilin biosynthesis regulatory protein SpaR(gene name synonym)	psi-mi:spak_baciu(display_long)|uniprotkb:spaK(gene name)|psi-mi:spaK(display_short)|uniprotkb:Subtilin biosynthesis sensor protein SpaK(gene name synonym)	psi-mi:"MI:0424"(protein kinase assay)	Chakicherla et al. (2009)	pubmed:19503843|doi:10.1371/journal.pcbi.1000401|imex:IM-13614	taxid:1423(baciu)|taxid:1423(Bacillus subtilis)	taxid:1423(baciu)|taxid:1423(Bacillus subtilis)	psi-mi:"MI:0844"(phosphotransfer reaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15786669|imex:IM-13614-1|dip:DIP-102595E	-	-	psi-mi:"MI:0843"(phosphate acceptor)	psi-mi:"MI:0842"(phosphate donor)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0000160"(phosphorelay signal transduction system)|go:"GO:0003677"(DNA binding)|go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR001789(Signal transduction response regulator, receiver region)|interpro:IPR001867(Signal transduction response regulator, C-terminal)|interpro:IPR011006(CheY-like)|interpro:IPR016032(Signal transduction response regulator, C-terminal effector)|interpro:IPR036388|interpro:IPR039420|go:"GO:0005737"(cytoplasm)|refseq:WP_003220039.1|dip:DIP-48346N	go:"GO:0000155"(phosphorelay sensor kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR003661(Signal transduction histidine kinase, subgroup 1, dimerisation and phosphoacceptor region)|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR008358(Signal transduction histidine kinase/phosphatase, lantibiotic regulatory protein MprB)|interpro:IPR036097|interpro:IPR036890|interpro:IPR044082|dip:DIP-48345N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/06	2017/08/10	rogid:1erDdB4HXqwn+CZgFaO+7kJVEh41423	rogid:auiW5rG+Ap7qssvhw0X72abmCMw1423	rigid:tBraO16OoF/MWKP3INa3bHtQ2Tg	false	phosphorylated residue:?-?	phosphorylated residue:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P33113	uniprotkb:P33113	intact:EBI-15786635	intact:EBI-15786635	psi-mi:spak_baciu(display_long)|uniprotkb:spaK(gene name)|psi-mi:spaK(display_short)|uniprotkb:Subtilin biosynthesis sensor protein SpaK(gene name synonym)	psi-mi:spak_baciu(display_long)|uniprotkb:spaK(gene name)|psi-mi:spaK(display_short)|uniprotkb:Subtilin biosynthesis sensor protein SpaK(gene name synonym)	psi-mi:"MI:0424"(protein kinase assay)	Chakicherla et al. (2009)	pubmed:19503843|doi:10.1371/journal.pcbi.1000401|imex:IM-13614	taxid:1423(baciu)|taxid:1423(Bacillus subtilis)	taxid:1423(baciu)|taxid:1423(Bacillus subtilis)	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15786690|imex:IM-13614-2|dip:DIP-102596E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0000155"(phosphorelay sensor kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR003661(Signal transduction histidine kinase, subgroup 1, dimerisation and phosphoacceptor region)|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR008358(Signal transduction histidine kinase/phosphatase, lantibiotic regulatory protein MprB)|interpro:IPR036097|interpro:IPR036890|interpro:IPR044082|dip:DIP-48345N	go:"GO:0000155"(phosphorelay sensor kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR003661(Signal transduction histidine kinase, subgroup 1, dimerisation and phosphoacceptor region)|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR008358(Signal transduction histidine kinase/phosphatase, lantibiotic regulatory protein MprB)|interpro:IPR036097|interpro:IPR036890|interpro:IPR044082|dip:DIP-48345N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/06	2017/08/10	rogid:auiW5rG+Ap7qssvhw0X72abmCMw1423	rogid:auiW5rG+Ap7qssvhw0X72abmCMw1423	rigid:U7N9rkABcba0g4dRUREqxSEatjo	false	mutation disrupting interaction:392-392	mutation disrupting interaction:247-247	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)