#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P32248	uniprotkb:P29067	intact:EBI-3401578|ensembl:ENSP00000246657	intact:EBI-1636616|ensembl:ENSRNOP00000026207	psi-mi:ccr7_human(display_long)|uniprotkb:CCR7(gene name)|psi-mi:CCR7(display_short)|uniprotkb:CMKBR7(gene name synonym)|uniprotkb:EBI1(gene name synonym)|uniprotkb:EVI1(gene name synonym)|uniprotkb:BLR2(gene name synonym)|uniprotkb:CDw197(gene name synonym)|uniprotkb:Epstein-Barr virus-induced G-protein coupled receptor 1(gene name synonym)|uniprotkb:MIP-3 beta receptor(gene name synonym)	psi-mi:arrb2_rat(display_long)|uniprotkb:Arrb2(gene name)|psi-mi:Arrb2(display_short)|uniprotkb:Arrestin beta-2(gene name synonym)	psi-mi:"MI:0055"(fluorescent resonance energy transfer)	Zidar et al. (2009)	pubmed:19497875|doi:10.1073/pnas.0904361106|imex:IM-22447	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:2364"(proximity)	psi-mi:"MI:0465"(DIP)	intact:EBI-15785979|imex:IM-22447-1|dip:DIP-196164E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0583"(fluorescence donor)	psi-mi:"MI:0584"(fluorescence acceptor)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|ensembl:ENSG00000126353(gene)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|ensembl:ENST00000246657(transcript)|go:"GO:0001768"(establishment of T cell polarity)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0016493"(C-C chemokine receptor activity)|go:"GO:0002407"(dendritic cell chemotaxis)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019957"(C-C chemokine binding)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0002408"(myeloid dendritic cell chemotaxis)|go:"GO:0031274"(positive regulation of pseudopodium assembly)|go:"GO:0031529"(ruffle organization)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0002885"(positive regulation of hypersensitivity)|go:"GO:0002922"(positive regulation of humoral immune response)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0032649"(regulation of interferon-gamma production)|go:"GO:0032651"(regulation of interleukin-1 beta production)|go:"GO:0005739"(mitochondrion)|go:"GO:0032695"(negative regulation of interleukin-12 production)|go:"GO:0005886"(plasma membrane)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0034695"(response to prostaglandin E)|go:"GO:0035757"("chemokine (C-C motif) ligand 19 binding")|go:"GO:0038117"(C-C motif chemokine 19 receptor activity)|go:"GO:0038121"(C-C motif chemokine 21 receptor activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:0050862"(positive regulation of T cell receptor signaling pathway)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0071731"(response to nitric oxide)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0097022"(lymphocyte migration into lymph node)|go:"GO:0097029"(mature conventional dendritic cell differentiation)|go:"GO:2000147"(positive regulation of cell motility)|go:"GO:2000510"(positive regulation of dendritic cell chemotaxis)|go:"GO:2000522"(positive regulation of immunological synapse formation)|go:"GO:2000525"(positive regulation of T cell costimulation)|go:"GO:2000526"(positive regulation of glycoprotein biosynthetic process involved in immunological synapse formation)|go:"GO:2000547"(regulation of dendritic cell dendrite assembly)|go:"GO:2000669"(negative regulation of dendritic cell apoptotic process)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000355(Chemokine receptor)|go:"GO:0035758"("chemokine (C-C motif) ligand 21 binding")|interpro:IPR001718(C-C chemokine receptor, type 7)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:6QZH|reactome:R-HSA-380108|reactome:R-HSA-418594|refseq:NP_001829.1|refseq:NP_001288643.1|refseq:NP_001288645.1|refseq:NP_001288646.1|refseq:NP_001288647.1|dip:DIP-5855N	rgd:2157|refseq:NP_037043.1|dip:DIP-40507N|ensembl:ENSRNOG00000019308(gene)|ensembl:ENSRNOT00000026207(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002031"(G protein-coupled receptor internalization)|go:"GO:0002032"(desensitization of G protein-coupled receptor signaling pathway by arrestin)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006897"(endocytosis)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007420"(brain development)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008277"(regulation of G protein-coupled receptor signaling pathway)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015031"(protein transport)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031623"(receptor internalization)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031691"(alpha-1A adrenergic receptor binding)|go:"GO:0031692"(alpha-1B adrenergic receptor binding)|go:"GO:0031701"(angiotensin receptor binding)|go:"GO:0031702"(type 1 angiotensin receptor binding)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0031762"(follicle-stimulating hormone receptor binding)|go:"GO:0031826"(type 2A serotonin receptor binding)|go:"GO:0031859"(platelet activating factor receptor binding)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032226"(positive regulation of synaptic transmission, dopaminergic)|go:"GO:0032691"(negative regulation of interleukin-1 beta production)|go:"GO:0032695"(negative regulation of interleukin-12 production)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034122"(negative regulation of toll-like receptor signaling pathway)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0034392"(negative regulation of smooth muscle cell apoptotic process)|go:"GO:0042699"(follicle-stimulating hormone signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045953"(negative regulation of natural killer cell mediated cytotoxicity)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050965"(detection of temperature stimulus involved in sensory perception of pain)|go:"GO:0051019"(mitogen-activated protein kinase binding)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051928"(positive regulation of calcium ion transport)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|go:"GO:1904037"(positive regulation of epithelial cell apoptotic process)|go:"GO:1990763"(arrestin family protein binding)|go:"GO:2000573"(positive regulation of DNA biosynthetic process)|go:"GO:2000727"(positive regulation of cardiac muscle cell differentiation)|interpro:IPR000698(Arrestin)|interpro:IPR011021(Arrestin-like, N-terminal)|interpro:IPR011022(Arrestin-like, C-terminal)|interpro:IPR014752(Arrestin, C-terminal)|interpro:IPR014753(Arrestin, N-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017864|rcsb pdb:6K3F|reactome:R-RNO-418555|reactome:R-RNO-456926|reactome:R-RNO-5099900|reactome:R-RNO-5635838|reactome:R-RNO-5674135|reactome:R-RNO-5689880|reactome:R-RNO-8856825|reactome:R-RNO-8856828	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/06	2017/08/10	rogid:dfneBfr/6GxvjUI8dc9dUsqQWp09606	rogid:CmLKfjz9uKH8AcfJcGB/SlhkeuE10116	rigid:/c2lDGLj1b/qCtkQFILzIkcb84g	false	cyan fluorescent protein tag:c-c	yellow fluorescent protein tag:c-c	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)