#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q8BVE8-2 uniprotkb:Q64213 intact:EBI-11518042|ensembl:ENSMUSP00000067205|ensembl:ENSMUSP00000075210 intact:EBI-8312835|uniprotkb:O08817|uniprotkb:Q61454|uniprotkb:P70167|uniprotkb:Q921Z4|intact:MINT-4134251|uniprotkb:E9QK02 psi-mi:q8bve8-2(display_long)|uniprotkb:Kiaa1090(gene name synonym)|uniprotkb:Nsd2(gene name)|psi-mi:Nsd2(display_short)|uniprotkb:Whsc1(gene name synonym)|uniprotkb:Multiple myeloma SET domain-containing protein(gene name synonym)|uniprotkb:Nuclear SET domain-containing protein 2(gene name synonym)|uniprotkb:Wolf-Hirschhorn syndrome candidate 1 protein homolog(gene name synonym) psi-mi:sf01_mouse(display_long)|uniprotkb:Sf1(gene name)|psi-mi:Sf1(display_short)|uniprotkb:Zfm1(gene name synonym)|uniprotkb:Zfp162(gene name synonym)|uniprotkb:Mammalian branch point-binding protein(gene name synonym)|uniprotkb:Zinc finger protein 162(gene name synonym)|uniprotkb:Transcription factor ZFM1(gene name synonym)|uniprotkb:Zinc finger gene in MEN1 locus(gene name synonym)|uniprotkb:CW17(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Nimura et al. (2009) pubmed:19483677|doi:10.1038/nature08086|imex:IM-21503 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15784976|imex:IM-21503-1|dip:DIP-191744E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-8847927(isoform-parent)|ensembl:ENSMUSG00000057406(gene)|ensembl:ENSMUST00000066854(transcript)|ensembl:ENSMUST00000075812(transcript) go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016604"(nuclear body)|go:"GO:0030238"(male sex determination)|go:"GO:0030575"(nuclear body organization)|go:"GO:0033327"(Leydig cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045131"(pre-mRNA branch point binding)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0050810"(regulation of steroid biosynthetic process)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR031150|interpro:IPR032570|interpro:IPR036612|reactome:R-MMU-72163|dip:DIP-60453N|mint:Q64213 psi-mi:"MI:0465"(dip) - comment:mint|function:"Necessary for the ATP-dependent first step of spliceosome assembly. Binds to the intron branch point sequence (BPS) 5'-UACUAAC-3' of the pre-mRNA. May act as transcription repressor" full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse)|taxid:10090(Mus musculus) - 2017/08/06 2017/08/10 rogid:Nw5cKBOX5XzUL7yM1BqRSAMGLMk10090 rogid:ykXZgj4QmBT8zKv15henuho9qvs10090 rigid:CoGmeMjeG9gIMkmruijZji4Z6Zg false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q8BVE8-2 uniprotkb:Q9CW46 intact:EBI-11518042|ensembl:ENSMUSP00000067205|ensembl:ENSMUSP00000075210 intact:EBI-644967|uniprotkb:Q5DTT6|uniprotkb:Q811K0|uniprotkb:Q8C3Z1|uniprotkb:Q8CA14|ensembl:ENSMUSP00000111150|ensembl:ENSMUSP00000151195 psi-mi:q8bve8-2(display_long)|uniprotkb:Kiaa1090(gene name synonym)|uniprotkb:Nsd2(gene name)|psi-mi:Nsd2(display_short)|uniprotkb:Whsc1(gene name synonym)|uniprotkb:Multiple myeloma SET domain-containing protein(gene name synonym)|uniprotkb:Nuclear SET domain-containing protein 2(gene name synonym)|uniprotkb:Wolf-Hirschhorn syndrome candidate 1 protein homolog(gene name synonym) psi-mi:ravr1_mouse(display_long)|uniprotkb:Protein raver-1(gene name synonym)|uniprotkb:Raver1(gene name)|psi-mi:Raver1(display_short)|uniprotkb:Kiaa1978(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Nimura et al. (2009) pubmed:19483677|doi:10.1038/nature08086|imex:IM-21503 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15784976|imex:IM-21503-1|dip:DIP-191744E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-8847927(isoform-parent)|ensembl:ENSMUSG00000057406(gene)|ensembl:ENSMUST00000066854(transcript)|ensembl:ENSMUST00000075812(transcript) refseq:NP_082187.1|ensembl:ENSMUSG00000010205(gene)|ensembl:ENSMUSG00000111497(gene)|ensembl:ENSMUST00000115487(transcript)|ensembl:ENSMUST00000217359(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034633|interpro:IPR034635|interpro:IPR035979|mint:Q9CW46|rcsb pdb:1WI6|rcsb pdb:3ZZY|rcsb pdb:3ZZZ|dip:DIP-44609N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse)|taxid:10090(Mus musculus) - 2017/08/06 2017/08/10 rogid:Nw5cKBOX5XzUL7yM1BqRSAMGLMk10090 rogid:8tlOX5yFmrXkpW1qGwJLK4alHqM10090 rigid:CoGmeMjeG9gIMkmruijZji4Z6Zg false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q8BVE8-2 uniprotkb:Q8CGY8 intact:EBI-11518042|ensembl:ENSMUSP00000067205|ensembl:ENSMUSP00000075210 intact:EBI-928496|uniprotkb:A2ALY1|uniprotkb:Q6PG10|uniprotkb:Q8BXH6|uniprotkb:Q91Y38|ensembl:ENSMUSP00000045409 psi-mi:q8bve8-2(display_long)|uniprotkb:Kiaa1090(gene name synonym)|uniprotkb:Nsd2(gene name)|psi-mi:Nsd2(display_short)|uniprotkb:Whsc1(gene name synonym)|uniprotkb:Multiple myeloma SET domain-containing protein(gene name synonym)|uniprotkb:Nuclear SET domain-containing protein 2(gene name synonym)|uniprotkb:Wolf-Hirschhorn syndrome candidate 1 protein homolog(gene name synonym) psi-mi:ogt1_mouse(display_long)|uniprotkb:Ogt(gene name)|psi-mi:Ogt(display_short)|uniprotkb:O-linked N-acetylglucosamine transferase 110 kDa subunit(gene name synonym)|uniprotkb:O-GlcNAc transferase subunit p110(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Nimura et al. (2009) pubmed:19483677|doi:10.1038/nature08086|imex:IM-21503 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15784976|imex:IM-21503-1|dip:DIP-191744E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-8847927(isoform-parent)|ensembl:ENSMUSG00000057406(gene)|ensembl:ENSMUST00000066854(transcript)|ensembl:ENSMUST00000075812(transcript) refseq:XP_006527799.1|refseq:NP_631883.2|refseq:NP_001277464.1|refseq:XP_011245805.1|dip:DIP-35700N|ensembl:ENSMUSG00000034160(gene)|ensembl:ENSMUST00000044475(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000791"(euchromatin)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003824"(catalytic activity)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006041"(glucosamine metabolic process)|go:"GO:0006110"(regulation of glycolytic process)|go:"GO:0006111"(regulation of gluconeogenesis)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006493"(protein O-linked glycosylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0008080"(N-acetyltransferase activity)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0016262"(protein N-acetylglucosaminyltransferase activity)|go:"GO:0016485"(protein processing)|go:"GO:0017122"(protein N-acetylglucosaminyltransferase complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032868"(response to insulin)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0042277"(peptide binding)|go:"GO:0042588"(zymogen granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046626"(regulation of insulin receptor signaling pathway)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0048029"(monosaccharide binding)|go:"GO:0048312"(intracellular distribution of mitochondria)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:0090315"(negative regulation of protein targeting to membrane)|go:"GO:0097363"(protein O-GlcNAc transferase activity)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1900038"(negative regulation of cellular response to hypoxia)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1903428"(positive regulation of reactive oxygen species biosynthetic process)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR029489|interpro:IPR037919|mint:Q8CGY8|reactome:R-MMU-3214847|reactome:R-MMU-5675482|reactome:R-MMU-5689603 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse)|taxid:10090(Mus musculus) - 2017/08/06 2017/08/10 rogid:Nw5cKBOX5XzUL7yM1BqRSAMGLMk10090 rogid:5N8o2WxL0V7gh1ZEa3l30GbrZa810090 rigid:CoGmeMjeG9gIMkmruijZji4Z6Zg false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q8BVE8-2 uniprotkb:O88568 intact:EBI-11518042|ensembl:ENSMUSP00000067205|ensembl:ENSMUSP00000075210 intact:EBI-6876888 psi-mi:q8bve8-2(display_long)|uniprotkb:Kiaa1090(gene name synonym)|uniprotkb:Nsd2(gene name)|psi-mi:Nsd2(display_short)|uniprotkb:Whsc1(gene name synonym)|uniprotkb:Multiple myeloma SET domain-containing protein(gene name synonym)|uniprotkb:Nuclear SET domain-containing protein 2(gene name synonym)|uniprotkb:Wolf-Hirschhorn syndrome candidate 1 protein homolog(gene name synonym) psi-mi:o88568_mouse(display_long)|uniprotkb:Hnrnpu(gene name)|psi-mi:Hnrnpu(display_short)|uniprotkb:hnRNP U(gene name synonym)|uniprotkb:Hnrpu(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Nimura et al. (2009) pubmed:19483677|doi:10.1038/nature08086|imex:IM-21503 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15784976|imex:IM-21503-1|dip:DIP-191744E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-8847927(isoform-parent)|ensembl:ENSMUSG00000057406(gene)|ensembl:ENSMUST00000066854(transcript)|ensembl:ENSMUST00000075812(transcript) go:"GO:0005634"(nucleus)|go:"GO:0099524"(postsynaptic cytosol)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR026745|interpro:IPR027417|interpro:IPR003034(DNA-binding SAP)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR043136|mint:O88568|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR035778|interpro:IPR036361 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse)|taxid:10090(Mus musculus) - 2017/08/06 2017/08/10 rogid:Nw5cKBOX5XzUL7yM1BqRSAMGLMk10090 rogid:x2zEhiSAyM7e+nBh7xOnMt3SuYU10090 rigid:CoGmeMjeG9gIMkmruijZji4Z6Zg false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q8BVE8-2 uniprotkb:Q9ER74 intact:EBI-11518042|ensembl:ENSMUSP00000067205|ensembl:ENSMUSP00000075210 intact:EBI-2312562|uniprotkb:Q920R5 psi-mi:q8bve8-2(display_long)|uniprotkb:Kiaa1090(gene name synonym)|uniprotkb:Nsd2(gene name)|psi-mi:Nsd2(display_short)|uniprotkb:Whsc1(gene name synonym)|uniprotkb:Multiple myeloma SET domain-containing protein(gene name synonym)|uniprotkb:Nuclear SET domain-containing protein 2(gene name synonym)|uniprotkb:Wolf-Hirschhorn syndrome candidate 1 protein homolog(gene name synonym) psi-mi:sall1_mouse(display_long)|uniprotkb:Sall1(gene name)|psi-mi:Sall1(display_short)|uniprotkb:Sal3(gene name synonym)|uniprotkb:Zinc finger protein Spalt-3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Nimura et al. (2009) pubmed:19483677|doi:10.1038/nature08086|imex:IM-21503 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15784976|imex:IM-21503-1|dip:DIP-191744E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-8847927(isoform-parent)|ensembl:ENSMUSG00000057406(gene)|ensembl:ENSMUST00000066854(transcript)|ensembl:ENSMUST00000075812(transcript) dip:DIP-54906N|go:"GO:0021553"(olfactory nerve development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0021889"(olfactory bulb interneuron differentiation)|go:"GO:0021915"(neural tube development)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0031129"(inductive cell-cell signaling)|go:"GO:0035136"(forelimb morphogenesis)|go:"GO:0035137"(hindlimb morphogenesis)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048566"(embryonic digestive tract development)|go:"GO:0001657"(ureteric bud development)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001822"(kidney development)|go:"GO:0001843"(neural tube closure)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003337"(mesenchymal to epithelial transition involved in metanephros morphogenesis)|go:"GO:0003340"(negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007507"(heart development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0010369"(chromocenter)|go:"GO:0016581"(NuRD complex)|go:"GO:0060173"(limb development)|go:"GO:0061034"(olfactory bulb mitral cell layer development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0072073"(kidney epithelium development)|go:"GO:0072092"(ureteric bud invasion)|go:"GO:0072309"(mesenchymal stem cell maintenance involved in metanephric nephron morphogenesis)|go:"GO:0090190"(positive regulation of branching involved in ureteric bud morphogenesis)|go:"GO:2000177"(regulation of neural precursor cell proliferation)|go:"GO:2000381"(negative regulation of mesoderm development)|go:"GO:2000384"(negative regulation of ectoderm development)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000792"(heterochromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse)|taxid:10090(Mus musculus) - 2017/08/06 2017/08/10 rogid:Nw5cKBOX5XzUL7yM1BqRSAMGLMk10090 rogid:Izbkv4nqxte6ww3HvP4XCCueQGg10090 rigid:CoGmeMjeG9gIMkmruijZji4Z6Zg false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q8BVE8-2 uniprotkb:Q3TKT4 intact:EBI-11518042|ensembl:ENSMUSP00000067205|ensembl:ENSMUSP00000075210 intact:EBI-1210244|uniprotkb:Q6AXG8|uniprotkb:Q3TUD7|ensembl:ENSMUSP00000133922 psi-mi:q8bve8-2(display_long)|uniprotkb:Kiaa1090(gene name synonym)|uniprotkb:Nsd2(gene name)|psi-mi:Nsd2(display_short)|uniprotkb:Whsc1(gene name synonym)|uniprotkb:Multiple myeloma SET domain-containing protein(gene name synonym)|uniprotkb:Nuclear SET domain-containing protein 2(gene name synonym)|uniprotkb:Wolf-Hirschhorn syndrome candidate 1 protein homolog(gene name synonym) psi-mi:smca4_mouse(display_long)|uniprotkb:Smarca4(gene name)|psi-mi:Smarca4(display_short)|uniprotkb:Baf190a(gene name synonym)|uniprotkb:Brg1(gene name synonym)|uniprotkb:Snf2b(gene name synonym)|uniprotkb:Snf2l4(gene name synonym)|uniprotkb:ATP-dependent helicase SMARCA4(gene name synonym)|uniprotkb:BRG1-associated factor 190A(gene name synonym)|uniprotkb:Protein brahma homolog 1(gene name synonym)|uniprotkb:SNF2-beta(gene name synonym)|uniprotkb:SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Nimura et al. (2009) pubmed:19483677|doi:10.1038/nature08086|imex:IM-21503 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15784976|imex:IM-21503-1|dip:DIP-191744E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-8847927(isoform-parent)|ensembl:ENSMUSG00000057406(gene)|ensembl:ENSMUST00000066854(transcript)|ensembl:ENSMUST00000075812(transcript) refseq:NP_001167549.1|refseq:NP_001167550.1|refseq:NP_035547.2|refseq:XP_006510180.2|refseq:XP_006510182.2|refseq:XP_006510183.2|dip:DIP-40650N|dip:DIP-59249N|ensembl:ENSMUSG00000032187(gene)|ensembl:ENSMUST00000174008(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001188"(RNA polymerase I preinitiation complex assembly)|go:"GO:0001568"(blood vessel development)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001832"(blastocyst growth)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0001889"(liver development)|go:"GO:0002039"(p53 binding)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006346"(DNA methylation-dependent heterochromatin assembly)|go:"GO:0007399"(nervous system development)|go:"GO:0007403"(glial cell fate determination)|go:"GO:0007507"(heart development)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010424"(DNA methylation on cytosine within a CG sequence)|go:"GO:0010467"(gene expression)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0016787"(hydrolase activity)|go:"GO:0022008"(neurogenesis)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030900"(forebrain development)|go:"GO:0030902"(hindbrain development)|go:"GO:0030957"(Tat protein binding)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035887"(aortic smooth muscle cell differentiation)|go:"GO:0035904"(aorta development)|go:"GO:0043044"|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048562"(embryonic organ morphogenesis)|go:"GO:0048730"(epidermis morphogenesis)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060318"(definitive erythrocyte differentiation)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060766"(negative regulation of androgen receptor signaling pathway)|go:"GO:0060976"(coronary vasculature development)|go:"GO:0061626"(pharyngeal arch artery morphogenesis)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0070307"(lens fiber cell development)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0070615"|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:1901838"(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:"GO:1902661"(positive regulation of glucose mediated signaling pathway)|go:"GO:1902895"(positive regulation of miRNA transcription)|interpro:IPR000330(SNF2-related)|interpro:IPR001487(Bromodomain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006576(BRK)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014012(Helicase/SANT-associated, DNA binding)|interpro:IPR014978(QLQ)|interpro:IPR018359|interpro:IPR027417|interpro:IPR029295|interpro:IPR030100|interpro:IPR036427|interpro:IPR038718|mint:Q3TKT4|reactome:R-MMU-1266695|reactome:R-MMU-201722|reactome:R-MMU-3214858|reactome:R-MMU-3247509|reactome:R-MMU-8939243|interpro:IPR037259 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse)|taxid:10090(Mus musculus) - 2017/08/06 2017/08/10 rogid:Nw5cKBOX5XzUL7yM1BqRSAMGLMk10090 rogid:uLQrygmWWugY//OpA2aX4t2VgmM10090 rigid:CoGmeMjeG9gIMkmruijZji4Z6Zg false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P42582 uniprotkb:Q8BVE8-2 intact:EBI-297021|ensembl:ENSMUSP00000015723|uniprotkb:P97335 intact:EBI-11518042|ensembl:ENSMUSP00000067205|ensembl:ENSMUSP00000075210 psi-mi:nkx25_mouse(display_long)|uniprotkb:Nkx2-5(gene name)|psi-mi:Nkx2-5(display_short)|uniprotkb:Csx(gene name synonym)|uniprotkb:Nkx-2.5(gene name synonym)|uniprotkb:Nkx2e(gene name synonym)|uniprotkb:Homeobox protein NK-2 homolog E(gene name synonym)|uniprotkb:Cardiac-specific homeobox(gene name synonym)|uniprotkb:Homeobox protein CSX(gene name synonym) psi-mi:q8bve8-2(display_long)|uniprotkb:Kiaa1090(gene name synonym)|uniprotkb:Nsd2(gene name)|psi-mi:Nsd2(display_short)|uniprotkb:Whsc1(gene name synonym)|uniprotkb:Multiple myeloma SET domain-containing protein(gene name synonym)|uniprotkb:Nuclear SET domain-containing protein 2(gene name synonym)|uniprotkb:Wolf-Hirschhorn syndrome candidate 1 protein homolog(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Nimura et al. (2009) pubmed:19483677|doi:10.1038/nature08086|imex:IM-21503 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15785053|imex:IM-21503-4|dip:DIP-191750E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048536"(spleen development)|go:"GO:0048738"(cardiac muscle tissue development)|go:"GO:0051891"(positive regulation of cardioblast differentiation)|go:"GO:0055005"(ventricular cardiac myofibril assembly)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055014"(atrial cardiac muscle cell development)|go:"GO:0055015"(ventricular cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060037"(pharyngeal system development)|go:"GO:0060038"(cardiac muscle cell proliferation)|go:"GO:0060043"(regulation of cardiac muscle cell proliferation)|go:"GO:0060047"(heart contraction)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060412"(ventricular septum morphogenesis)|go:"GO:0060413"(atrial septum morphogenesis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0060928"(atrioventricular node cell development)|go:"GO:0060929"(atrioventricular node cell fate commitment)|go:"GO:0060971"(embryonic heart tube left/right pattern formation)|go:"GO:0072359"(circulatory system development)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1903779"(regulation of cardiac conduction)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR033629|rcsb pdb:5FLV|ensembl:ENSMUSG00000015579(gene)|ensembl:ENSMUST00000015723(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001947"(heart looping)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003148"(outflow tract septum morphogenesis)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0003162"(atrioventricular node development)|go:"GO:0003166"(bundle of His development)|go:"GO:0003168"(Purkinje myocyte differentiation)|go:"GO:0003208"(cardiac ventricle morphogenesis)|go:"GO:0003211"(cardiac ventricle formation)|go:"GO:0003221"(right ventricular cardiac muscle tissue morphogenesis)|go:"GO:0003222"(ventricular trabecula myocardium morphogenesis)|go:"GO:0003228"(atrial cardiac muscle tissue development)|go:"GO:0003278"(apoptotic process involved in heart morphogenesis)|go:"GO:0003285"(septum secundum development)|go:"GO:0003342"(proepicardium development)|go:"GO:0003350"(pulmonary myocardium development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0003161"(cardiac conduction system development)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007492"(endoderm development)|go:"GO:0007507"(heart development)|go:"GO:0007512"(adult heart development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010667"(negative regulation of cardiac muscle cell apoptotic process)|go:"GO:0010735"(positive regulation of transcription via serum response element binding)|go:"GO:0010765"(positive regulation of sodium ion transport)|go:"GO:0010832"(negative regulation of myotube differentiation)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0030878"(thyroid gland development)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0035050"(embryonic heart tube development)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043586"(tongue development)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045823"(positive regulation of heart contraction)|refseq:NP_032726.1|refseq:XP_006523860.1|dip:DIP-33031N intact:EBI-8847927(isoform-parent)|ensembl:ENSMUSG00000057406(gene)|ensembl:ENSMUST00000066854(transcript)|ensembl:ENSMUST00000075812(transcript) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse)|taxid:10090(Mus musculus) - 2017/08/06 2017/08/10 rogid:/U1x7rZvb4/qIpJkF1tQMZ0UF7A10090 rogid:Nw5cKBOX5XzUL7yM1BqRSAMGLMk10090 rigid:PWjs0SXPKPFVP/yLB5IaKTM8UYk false ha tag:n-n flag tag:?-?|sufficient binding region:453-521 - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8BVE8-2 uniprotkb:Q8CGY8 intact:EBI-11518042|ensembl:ENSMUSP00000067205|ensembl:ENSMUSP00000075210 intact:EBI-928496|uniprotkb:A2ALY1|uniprotkb:Q6PG10|uniprotkb:Q8BXH6|uniprotkb:Q91Y38|ensembl:ENSMUSP00000045409 psi-mi:q8bve8-2(display_long)|uniprotkb:Kiaa1090(gene name synonym)|uniprotkb:Nsd2(gene name)|psi-mi:Nsd2(display_short)|uniprotkb:Whsc1(gene name synonym)|uniprotkb:Multiple myeloma SET domain-containing protein(gene name synonym)|uniprotkb:Nuclear SET domain-containing protein 2(gene name synonym)|uniprotkb:Wolf-Hirschhorn syndrome candidate 1 protein homolog(gene name synonym) psi-mi:ogt1_mouse(display_long)|uniprotkb:Ogt(gene name)|psi-mi:Ogt(display_short)|uniprotkb:O-linked N-acetylglucosamine transferase 110 kDa subunit(gene name synonym)|uniprotkb:O-GlcNAc transferase subunit p110(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Nimura et al. (2009) pubmed:19483677|doi:10.1038/nature08086|imex:IM-21503 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15785029|imex:IM-21503-3|dip:DIP-191748E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-8847927(isoform-parent)|ensembl:ENSMUSG00000057406(gene)|ensembl:ENSMUST00000066854(transcript)|ensembl:ENSMUST00000075812(transcript) refseq:XP_006527799.1|refseq:NP_631883.2|refseq:NP_001277464.1|refseq:XP_011245805.1|dip:DIP-35700N|ensembl:ENSMUSG00000034160(gene)|ensembl:ENSMUST00000044475(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000791"(euchromatin)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003824"(catalytic activity)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006041"(glucosamine metabolic process)|go:"GO:0006110"(regulation of glycolytic process)|go:"GO:0006111"(regulation of gluconeogenesis)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006493"(protein O-linked glycosylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0008080"(N-acetyltransferase activity)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0016262"(protein N-acetylglucosaminyltransferase activity)|go:"GO:0016485"(protein processing)|go:"GO:0017122"(protein N-acetylglucosaminyltransferase complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032868"(response to insulin)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0042277"(peptide binding)|go:"GO:0042588"(zymogen granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046626"(regulation of insulin receptor signaling pathway)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0048029"(monosaccharide binding)|go:"GO:0048312"(intracellular distribution of mitochondria)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:0090315"(negative regulation of protein targeting to membrane)|go:"GO:0097363"(protein O-GlcNAc transferase activity)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1900038"(negative regulation of cellular response to hypoxia)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1903428"(positive regulation of reactive oxygen species biosynthetic process)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR029489|interpro:IPR037919|mint:Q8CGY8|reactome:R-MMU-3214847|reactome:R-MMU-5675482|reactome:R-MMU-5689603 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse)|taxid:10090(Mus musculus) - 2017/08/06 2017/08/10 rogid:Nw5cKBOX5XzUL7yM1BqRSAMGLMk10090 rogid:5N8o2WxL0V7gh1ZEa3l30GbrZa810090 rigid:quLQM/XemXUzAGjJCAYhI48Zmdo false flag tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8BVE8-2 uniprotkb:Q8BX22 intact:EBI-11518042|ensembl:ENSMUSP00000067205|ensembl:ENSMUSP00000075210 intact:EBI-2312582|uniprotkb:A2AV00|uniprotkb:Q6S7E8|uniprotkb:Q6S7E9|uniprotkb:Q7TST6|ensembl:ENSMUSP00000029061 psi-mi:q8bve8-2(display_long)|uniprotkb:Kiaa1090(gene name synonym)|uniprotkb:Nsd2(gene name)|psi-mi:Nsd2(display_short)|uniprotkb:Whsc1(gene name synonym)|uniprotkb:Multiple myeloma SET domain-containing protein(gene name synonym)|uniprotkb:Nuclear SET domain-containing protein 2(gene name synonym)|uniprotkb:Wolf-Hirschhorn syndrome candidate 1 protein homolog(gene name synonym) psi-mi:sall4_mouse(display_long)|uniprotkb:Sall4(gene name)|psi-mi:Sall4(display_short)|uniprotkb:Zinc finger protein SALL4(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Nimura et al. (2009) pubmed:19483677|doi:10.1038/nature08086|imex:IM-21503 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15785029|imex:IM-21503-3|dip:DIP-191748E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-8847927(isoform-parent)|ensembl:ENSMUSG00000057406(gene)|ensembl:ENSMUST00000066854(transcript)|ensembl:ENSMUST00000075812(transcript) refseq:NP_780512.2|refseq:NP_958797.2|refseq:NP_958798.2|dip:DIP-29926N|ensembl:ENSMUSG00000027547(gene)|ensembl:ENSMUST00000029061(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000792"(heterochromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001833"(inner cell mass cell proliferation)|go:"GO:0001843"(neural tube closure)|go:"GO:0003281"(ventricular septum development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009888"(tissue development)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021915"(neural tube development)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q8BX22|reactome:R-MMU-8943724 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse)|taxid:10090(Mus musculus) - 2017/08/06 2017/08/10 rogid:Nw5cKBOX5XzUL7yM1BqRSAMGLMk10090 rogid:84RTcgupqeb0ypojGiwpAezUWVw10090 rigid:quLQM/XemXUzAGjJCAYhI48Zmdo false flag tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8BVE8-2 uniprotkb:Q80Z64 intact:EBI-11518042|ensembl:ENSMUSP00000067205|ensembl:ENSMUSP00000075210 intact:EBI-2312517|uniprotkb:Q6SMR1|uniprotkb:Q7TN85|ensembl:ENSMUSP00000012540 psi-mi:q8bve8-2(display_long)|uniprotkb:Kiaa1090(gene name synonym)|uniprotkb:Nsd2(gene name)|psi-mi:Nsd2(display_short)|uniprotkb:Whsc1(gene name synonym)|uniprotkb:Multiple myeloma SET domain-containing protein(gene name synonym)|uniprotkb:Nuclear SET domain-containing protein 2(gene name synonym)|uniprotkb:Wolf-Hirschhorn syndrome candidate 1 protein homolog(gene name synonym) psi-mi:nanog_mouse(display_long)|uniprotkb:Nanog(gene name)|psi-mi:Nanog(display_short)|uniprotkb:Ecat4(gene name synonym)|uniprotkb:Enk(gene name synonym)|uniprotkb:Homeobox transcription factor Nanog(gene name synonym)|uniprotkb:Early embryo specific expression NK-type homeobox protein(gene name synonym)|uniprotkb:ES cell-associated protein 4(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Nimura et al. (2009) pubmed:19483677|doi:10.1038/nature08086|imex:IM-21503 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15785029|imex:IM-21503-3|dip:DIP-191748E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-8847927(isoform-parent)|ensembl:ENSMUSG00000057406(gene)|ensembl:ENSMUST00000066854(transcript)|ensembl:ENSMUST00000075812(transcript) refseq:NP_001276757.1|refseq:NP_001276759.1|refseq:NP_001276760.1|refseq:NP_082292.1|refseq:XP_006506714.1|dip:DIP-29932N|ensembl:ENSMUSG00000012396(gene)|ensembl:ENSMUST00000012540(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001010"(RNA polymerase II sequence-specific DNA-binding transcription factor recruiting activity)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001710"(mesodermal cell fate commitment)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008406"(gonad development)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0010033"(response to organic substance)|go:"GO:0010454"(negative regulation of cell fate commitment)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0017145"(stem cell division)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0042664"(negative regulation of endodermal cell fate specification)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043697"(cell dedifferentiation)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048863"(stem cell differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000035"(regulation of stem cell division)|go:"GO:2000648"(positive regulation of stem cell proliferation)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|mint:Q80Z64|rcsb pdb:2VI6 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse)|taxid:10090(Mus musculus) - 2017/08/06 2017/08/10 rogid:Nw5cKBOX5XzUL7yM1BqRSAMGLMk10090 rogid:v8TDhd7PZnOKFS3djxouMHxftPs10090 rigid:quLQM/XemXUzAGjJCAYhI48Zmdo false flag tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8BVE8-2 uniprotkb:Q9ER74 intact:EBI-11518042|ensembl:ENSMUSP00000067205|ensembl:ENSMUSP00000075210 intact:EBI-2312562|uniprotkb:Q920R5 psi-mi:q8bve8-2(display_long)|uniprotkb:Kiaa1090(gene name synonym)|uniprotkb:Nsd2(gene name)|psi-mi:Nsd2(display_short)|uniprotkb:Whsc1(gene name synonym)|uniprotkb:Multiple myeloma SET domain-containing protein(gene name synonym)|uniprotkb:Nuclear SET domain-containing protein 2(gene name synonym)|uniprotkb:Wolf-Hirschhorn syndrome candidate 1 protein homolog(gene name synonym) psi-mi:sall1_mouse(display_long)|uniprotkb:Sall1(gene name)|psi-mi:Sall1(display_short)|uniprotkb:Sal3(gene name synonym)|uniprotkb:Zinc finger protein Spalt-3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Nimura et al. (2009) pubmed:19483677|doi:10.1038/nature08086|imex:IM-21503 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15785029|imex:IM-21503-3|dip:DIP-191748E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-8847927(isoform-parent)|ensembl:ENSMUSG00000057406(gene)|ensembl:ENSMUST00000066854(transcript)|ensembl:ENSMUST00000075812(transcript) dip:DIP-54906N|go:"GO:0021553"(olfactory nerve development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0021889"(olfactory bulb interneuron differentiation)|go:"GO:0021915"(neural tube development)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0031129"(inductive cell-cell signaling)|go:"GO:0035136"(forelimb morphogenesis)|go:"GO:0035137"(hindlimb morphogenesis)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048566"(embryonic digestive tract development)|go:"GO:0001657"(ureteric bud development)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001822"(kidney development)|go:"GO:0001843"(neural tube closure)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003337"(mesenchymal to epithelial transition involved in metanephros morphogenesis)|go:"GO:0003340"(negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007507"(heart development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0010369"(chromocenter)|go:"GO:0016581"(NuRD complex)|go:"GO:0060173"(limb development)|go:"GO:0061034"(olfactory bulb mitral cell layer development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0072073"(kidney epithelium development)|go:"GO:0072092"(ureteric bud invasion)|go:"GO:0072309"(mesenchymal stem cell maintenance involved in metanephric nephron morphogenesis)|go:"GO:0090190"(positive regulation of branching involved in ureteric bud morphogenesis)|go:"GO:2000177"(regulation of neural precursor cell proliferation)|go:"GO:2000381"(negative regulation of mesoderm development)|go:"GO:2000384"(negative regulation of ectoderm development)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000792"(heterochromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse)|taxid:10090(Mus musculus) - 2017/08/06 2017/08/10 rogid:Nw5cKBOX5XzUL7yM1BqRSAMGLMk10090 rogid:Izbkv4nqxte6ww3HvP4XCCueQGg10090 rigid:quLQM/XemXUzAGjJCAYhI48Zmdo false flag tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8BVE8-2 uniprotkb:Q80Z64 intact:EBI-11518042|ensembl:ENSMUSP00000067205|ensembl:ENSMUSP00000075210 intact:EBI-2312517|uniprotkb:Q6SMR1|uniprotkb:Q7TN85|ensembl:ENSMUSP00000012540 psi-mi:q8bve8-2(display_long)|uniprotkb:Kiaa1090(gene name synonym)|uniprotkb:Nsd2(gene name)|psi-mi:Nsd2(display_short)|uniprotkb:Whsc1(gene name synonym)|uniprotkb:Multiple myeloma SET domain-containing protein(gene name synonym)|uniprotkb:Nuclear SET domain-containing protein 2(gene name synonym)|uniprotkb:Wolf-Hirschhorn syndrome candidate 1 protein homolog(gene name synonym) psi-mi:nanog_mouse(display_long)|uniprotkb:Nanog(gene name)|psi-mi:Nanog(display_short)|uniprotkb:Ecat4(gene name synonym)|uniprotkb:Enk(gene name synonym)|uniprotkb:Homeobox transcription factor Nanog(gene name synonym)|uniprotkb:Early embryo specific expression NK-type homeobox protein(gene name synonym)|uniprotkb:ES cell-associated protein 4(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Nimura et al. (2009) pubmed:19483677|doi:10.1038/nature08086|imex:IM-21503 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15785002|imex:IM-21503-2|dip:DIP-191745E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-8847927(isoform-parent)|ensembl:ENSMUSG00000057406(gene)|ensembl:ENSMUST00000066854(transcript)|ensembl:ENSMUST00000075812(transcript) refseq:NP_001276757.1|refseq:NP_001276759.1|refseq:NP_001276760.1|refseq:NP_082292.1|refseq:XP_006506714.1|dip:DIP-29932N|ensembl:ENSMUSG00000012396(gene)|ensembl:ENSMUST00000012540(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001010"(RNA polymerase II sequence-specific DNA-binding transcription factor recruiting activity)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001710"(mesodermal cell fate commitment)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008406"(gonad development)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0010033"(response to organic substance)|go:"GO:0010454"(negative regulation of cell fate commitment)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0017145"(stem cell division)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0042664"(negative regulation of endodermal cell fate specification)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043697"(cell dedifferentiation)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048863"(stem cell differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000035"(regulation of stem cell division)|go:"GO:2000648"(positive regulation of stem cell proliferation)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|mint:Q80Z64|rcsb pdb:2VI6 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse)|taxid:10090(Mus musculus) - 2017/08/06 2017/08/10 rogid:Nw5cKBOX5XzUL7yM1BqRSAMGLMk10090 rogid:v8TDhd7PZnOKFS3djxouMHxftPs10090 rigid:c//9xafcTuugxIK0mZYZxUCm2f4 false tandem tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8BVE8-2 uniprotkb:O09106 intact:EBI-11518042|ensembl:ENSMUSP00000067205|ensembl:ENSMUSP00000075210 intact:EBI-301912|uniprotkb:P97476|ensembl:ENSMUSP00000099657 psi-mi:q8bve8-2(display_long)|uniprotkb:Kiaa1090(gene name synonym)|uniprotkb:Nsd2(gene name)|psi-mi:Nsd2(display_short)|uniprotkb:Whsc1(gene name synonym)|uniprotkb:Multiple myeloma SET domain-containing protein(gene name synonym)|uniprotkb:Nuclear SET domain-containing protein 2(gene name synonym)|uniprotkb:Wolf-Hirschhorn syndrome candidate 1 protein homolog(gene name synonym) psi-mi:hdac1_mouse(display_long)|uniprotkb:Hdac1(gene name)|psi-mi:Hdac1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Nimura et al. (2009) pubmed:19483677|doi:10.1038/nature08086|imex:IM-21503 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15785002|imex:IM-21503-2|dip:DIP-191745E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-8847927(isoform-parent)|ensembl:ENSMUSG00000057406(gene)|ensembl:ENSMUST00000066854(transcript)|ensembl:ENSMUST00000075812(transcript) dip:DIP-31499N|ensembl:ENSMUSG00000028800(gene)|ensembl:ENSMUST00000102597(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|refseq:NP_032254.1|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0052548"(regulation of endopeptidase activity)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0060766"(negative regulation of androgen receptor signaling pathway)|go:"GO:0060789"(hair follicle placode formation)|go:"GO:0061029"(eyelid development in camera-type eye)|go:"GO:0061198"(fungiform papilla formation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070888"(E-box binding)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000273"(positive regulation of signaling receptor activity)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000757"(negative regulation of peptidyl-lysine acetylation)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|mint:O09106|reactome:R-MMU-1538133|reactome:R-MMU-201722|reactome:R-MMU-2173795|reactome:R-MMU-3214815|reactome:R-MMU-350054|reactome:R-MMU-3769402|reactome:R-MMU-4551638|reactome:R-MMU-6804758|reactome:R-MMU-73762|reactome:R-MMU-8936459|reactome:R-MMU-8943724|reactome:R-MMU-9018519|reactome:R-MMU-9022692|reactome:R-MMU-983231|go:"GO:2000676"(positive regulation of type B pancreatic cell apoptotic process)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019213"(deacetylase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0021766"(hippocampus development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031000"(response to caffeine)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032732"(positive regulation of interleukin-1 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035851"(Krueppel-associated box domain binding)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042493"|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0001975"(response to amphetamine)|go:"GO:0002039"(p53 binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006346"(DNA methylation-dependent heterochromatin assembly)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006476"(protein deacetylation)|go:"GO:0007492"(endoderm development)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009913"(epidermal cell differentiation)|go:"GO:0001046"(core promoter sequence-specific DNA binding) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse)|taxid:10090(Mus musculus) - 2017/08/06 2017/08/10 rogid:Nw5cKBOX5XzUL7yM1BqRSAMGLMk10090 rogid:P7QV++FiMiNcabUkswbnNhGVU3410090 rigid:c//9xafcTuugxIK0mZYZxUCm2f4 false tandem tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8BVE8-2 uniprotkb:P08775 intact:EBI-11518042|ensembl:ENSMUSP00000067205|ensembl:ENSMUSP00000075210 intact:EBI-2549849|ensembl:ENSMUSP00000050771|uniprotkb:Q5F298 psi-mi:q8bve8-2(display_long)|uniprotkb:Kiaa1090(gene name synonym)|uniprotkb:Nsd2(gene name)|psi-mi:Nsd2(display_short)|uniprotkb:Whsc1(gene name synonym)|uniprotkb:Multiple myeloma SET domain-containing protein(gene name synonym)|uniprotkb:Nuclear SET domain-containing protein 2(gene name synonym)|uniprotkb:Wolf-Hirschhorn syndrome candidate 1 protein homolog(gene name synonym) psi-mi:rpb1_mouse(display_long)|uniprotkb:Polr2a(gene name)|psi-mi:Polr2a(display_short)|uniprotkb:Rpii215(gene name synonym)|uniprotkb:Rpo2-1(gene name synonym)|uniprotkb:DNA-directed RNA polymerase II subunit A(gene name synonym)|uniprotkb:DNA-directed RNA polymerase III largest subunit(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Nimura et al. (2009) pubmed:19483677|doi:10.1038/nature08086|imex:IM-21503 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15785002|imex:IM-21503-2|dip:DIP-191745E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-8847927(isoform-parent)|ensembl:ENSMUSG00000057406(gene)|ensembl:ENSMUST00000066854(transcript)|ensembl:ENSMUST00000075812(transcript) ensembl:ENSMUSG00000005198(gene)|ensembl:ENSMUST00000058470(transcript)|go:"GO:0000791"(euchromatin)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0019900"(kinase binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0046872"(metal ion binding)|go:"GO:0071453"(cellular response to oxygen levels)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR000684(RNA polymerase II, heptapeptide repeat, eukaryotic)|interpro:IPR000722(RNA polymerase, alpha subunit)|interpro:IPR006592(RNA polymerase, N-terminal)|interpro:IPR007066(RNA polymerase Rpb1, domain 3)|interpro:IPR007073(RNA polymerase Rpb1, domain 7)|interpro:IPR007075(RNA polymerase Rpb1, domain 6)|interpro:IPR007080(RNA polymerase Rpb1, domain 1)|interpro:IPR007081(RNA polymerase Rpb1, domain 5)|interpro:IPR007083(RNA polymerase Rpb1, domain 4)|interpro:IPR038120|interpro:IPR038593|interpro:IPR042102|mint:P08775|reactome:R-MMU-113418|reactome:R-MMU-5578749|reactome:R-MMU-674695|reactome:R-MMU-6781823|reactome:R-MMU-6782135|reactome:R-MMU-6782210|reactome:R-MMU-6796648|reactome:R-MMU-6803529|reactome:R-MMU-6807505|reactome:R-MMU-72086|reactome:R-MMU-72163|reactome:R-MMU-72165|reactome:R-MMU-72203|reactome:R-MMU-73776|reactome:R-MMU-73779|reactome:R-MMU-75953|reactome:R-MMU-75955|reactome:R-MMU-76042|reactome:R-MMU-77075|reactome:R-MMU-9018519|reactome:R-MMU-112382|refseq:NP_001277997.1|dip:DIP-46369N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse)|taxid:10090(Mus musculus) - 2017/08/06 2017/08/10 rogid:Nw5cKBOX5XzUL7yM1BqRSAMGLMk10090 rogid:kUX/HdU6Y2VHAGjySBcOxfS08XA10090 rigid:c//9xafcTuugxIK0mZYZxUCm2f4 false tandem tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8BVE8-2 uniprotkb:Q8BX22 intact:EBI-11518042|ensembl:ENSMUSP00000067205|ensembl:ENSMUSP00000075210 intact:EBI-2312582|uniprotkb:A2AV00|uniprotkb:Q6S7E8|uniprotkb:Q6S7E9|uniprotkb:Q7TST6|ensembl:ENSMUSP00000029061 psi-mi:q8bve8-2(display_long)|uniprotkb:Kiaa1090(gene name synonym)|uniprotkb:Nsd2(gene name)|psi-mi:Nsd2(display_short)|uniprotkb:Whsc1(gene name synonym)|uniprotkb:Multiple myeloma SET domain-containing protein(gene name synonym)|uniprotkb:Nuclear SET domain-containing protein 2(gene name synonym)|uniprotkb:Wolf-Hirschhorn syndrome candidate 1 protein homolog(gene name synonym) psi-mi:sall4_mouse(display_long)|uniprotkb:Sall4(gene name)|psi-mi:Sall4(display_short)|uniprotkb:Zinc finger protein SALL4(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Nimura et al. (2009) pubmed:19483677|doi:10.1038/nature08086|imex:IM-21503 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15785002|imex:IM-21503-2|dip:DIP-191745E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-8847927(isoform-parent)|ensembl:ENSMUSG00000057406(gene)|ensembl:ENSMUST00000066854(transcript)|ensembl:ENSMUST00000075812(transcript) refseq:NP_780512.2|refseq:NP_958797.2|refseq:NP_958798.2|dip:DIP-29926N|ensembl:ENSMUSG00000027547(gene)|ensembl:ENSMUST00000029061(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000792"(heterochromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001833"(inner cell mass cell proliferation)|go:"GO:0001843"(neural tube closure)|go:"GO:0003281"(ventricular septum development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009888"(tissue development)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021915"(neural tube development)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q8BX22|reactome:R-MMU-8943724 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse)|taxid:10090(Mus musculus) - 2017/08/06 2017/08/10 rogid:Nw5cKBOX5XzUL7yM1BqRSAMGLMk10090 rogid:84RTcgupqeb0ypojGiwpAezUWVw10090 rigid:c//9xafcTuugxIK0mZYZxUCm2f4 false tandem tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8BVE8-2 uniprotkb:Q8CGY8 intact:EBI-11518042|ensembl:ENSMUSP00000067205|ensembl:ENSMUSP00000075210 intact:EBI-928496|uniprotkb:A2ALY1|uniprotkb:Q6PG10|uniprotkb:Q8BXH6|uniprotkb:Q91Y38|ensembl:ENSMUSP00000045409 psi-mi:q8bve8-2(display_long)|uniprotkb:Kiaa1090(gene name synonym)|uniprotkb:Nsd2(gene name)|psi-mi:Nsd2(display_short)|uniprotkb:Whsc1(gene name synonym)|uniprotkb:Multiple myeloma SET domain-containing protein(gene name synonym)|uniprotkb:Nuclear SET domain-containing protein 2(gene name synonym)|uniprotkb:Wolf-Hirschhorn syndrome candidate 1 protein homolog(gene name synonym) psi-mi:ogt1_mouse(display_long)|uniprotkb:Ogt(gene name)|psi-mi:Ogt(display_short)|uniprotkb:O-linked N-acetylglucosamine transferase 110 kDa subunit(gene name synonym)|uniprotkb:O-GlcNAc transferase subunit p110(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Nimura et al. (2009) pubmed:19483677|doi:10.1038/nature08086|imex:IM-21503 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15785002|imex:IM-21503-2|dip:DIP-191745E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-8847927(isoform-parent)|ensembl:ENSMUSG00000057406(gene)|ensembl:ENSMUST00000066854(transcript)|ensembl:ENSMUST00000075812(transcript) refseq:XP_006527799.1|refseq:NP_631883.2|refseq:NP_001277464.1|refseq:XP_011245805.1|dip:DIP-35700N|ensembl:ENSMUSG00000034160(gene)|ensembl:ENSMUST00000044475(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000791"(euchromatin)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003824"(catalytic activity)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006041"(glucosamine metabolic process)|go:"GO:0006110"(regulation of glycolytic process)|go:"GO:0006111"(regulation of gluconeogenesis)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006493"(protein O-linked glycosylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0008080"(N-acetyltransferase activity)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0016262"(protein N-acetylglucosaminyltransferase activity)|go:"GO:0016485"(protein processing)|go:"GO:0017122"(protein N-acetylglucosaminyltransferase complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032868"(response to insulin)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0042277"(peptide binding)|go:"GO:0042588"(zymogen granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046626"(regulation of insulin receptor signaling pathway)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0048029"(monosaccharide binding)|go:"GO:0048312"(intracellular distribution of mitochondria)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:0090315"(negative regulation of protein targeting to membrane)|go:"GO:0097363"(protein O-GlcNAc transferase activity)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1900038"(negative regulation of cellular response to hypoxia)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1903428"(positive regulation of reactive oxygen species biosynthetic process)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR029489|interpro:IPR037919|mint:Q8CGY8|reactome:R-MMU-3214847|reactome:R-MMU-5675482|reactome:R-MMU-5689603 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse)|taxid:10090(Mus musculus) - 2017/08/06 2017/08/10 rogid:Nw5cKBOX5XzUL7yM1BqRSAMGLMk10090 rogid:5N8o2WxL0V7gh1ZEa3l30GbrZa810090 rigid:c//9xafcTuugxIK0mZYZxUCm2f4 false tandem tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8BVE8-2 uniprotkb:Q9ER74 intact:EBI-11518042|ensembl:ENSMUSP00000067205|ensembl:ENSMUSP00000075210 intact:EBI-2312562|uniprotkb:Q920R5 psi-mi:q8bve8-2(display_long)|uniprotkb:Kiaa1090(gene name synonym)|uniprotkb:Nsd2(gene name)|psi-mi:Nsd2(display_short)|uniprotkb:Whsc1(gene name synonym)|uniprotkb:Multiple myeloma SET domain-containing protein(gene name synonym)|uniprotkb:Nuclear SET domain-containing protein 2(gene name synonym)|uniprotkb:Wolf-Hirschhorn syndrome candidate 1 protein homolog(gene name synonym) psi-mi:sall1_mouse(display_long)|uniprotkb:Sall1(gene name)|psi-mi:Sall1(display_short)|uniprotkb:Sal3(gene name synonym)|uniprotkb:Zinc finger protein Spalt-3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Nimura et al. (2009) pubmed:19483677|doi:10.1038/nature08086|imex:IM-21503 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15785002|imex:IM-21503-2|dip:DIP-191745E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-8847927(isoform-parent)|ensembl:ENSMUSG00000057406(gene)|ensembl:ENSMUST00000066854(transcript)|ensembl:ENSMUST00000075812(transcript) dip:DIP-54906N|go:"GO:0021553"(olfactory nerve development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0021889"(olfactory bulb interneuron differentiation)|go:"GO:0021915"(neural tube development)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0031129"(inductive cell-cell signaling)|go:"GO:0035136"(forelimb morphogenesis)|go:"GO:0035137"(hindlimb morphogenesis)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048566"(embryonic digestive tract development)|go:"GO:0001657"(ureteric bud development)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001822"(kidney development)|go:"GO:0001843"(neural tube closure)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003337"(mesenchymal to epithelial transition involved in metanephros morphogenesis)|go:"GO:0003340"(negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007507"(heart development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0010369"(chromocenter)|go:"GO:0016581"(NuRD complex)|go:"GO:0060173"(limb development)|go:"GO:0061034"(olfactory bulb mitral cell layer development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0072073"(kidney epithelium development)|go:"GO:0072092"(ureteric bud invasion)|go:"GO:0072309"(mesenchymal stem cell maintenance involved in metanephric nephron morphogenesis)|go:"GO:0090190"(positive regulation of branching involved in ureteric bud morphogenesis)|go:"GO:2000177"(regulation of neural precursor cell proliferation)|go:"GO:2000381"(negative regulation of mesoderm development)|go:"GO:2000384"(negative regulation of ectoderm development)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000792"(heterochromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse)|taxid:10090(Mus musculus) - 2017/08/06 2017/08/10 rogid:Nw5cKBOX5XzUL7yM1BqRSAMGLMk10090 rogid:Izbkv4nqxte6ww3HvP4XCCueQGg10090 rigid:c//9xafcTuugxIK0mZYZxUCm2f4 false tandem tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8BVE8-2 uniprotkb:Q3TKT4 intact:EBI-11518042|ensembl:ENSMUSP00000067205|ensembl:ENSMUSP00000075210 intact:EBI-1210244|uniprotkb:Q6AXG8|uniprotkb:Q3TUD7|ensembl:ENSMUSP00000133922 psi-mi:q8bve8-2(display_long)|uniprotkb:Kiaa1090(gene name synonym)|uniprotkb:Nsd2(gene name)|psi-mi:Nsd2(display_short)|uniprotkb:Whsc1(gene name synonym)|uniprotkb:Multiple myeloma SET domain-containing protein(gene name synonym)|uniprotkb:Nuclear SET domain-containing protein 2(gene name synonym)|uniprotkb:Wolf-Hirschhorn syndrome candidate 1 protein homolog(gene name synonym) psi-mi:smca4_mouse(display_long)|uniprotkb:Smarca4(gene name)|psi-mi:Smarca4(display_short)|uniprotkb:Baf190a(gene name synonym)|uniprotkb:Brg1(gene name synonym)|uniprotkb:Snf2b(gene name synonym)|uniprotkb:Snf2l4(gene name synonym)|uniprotkb:ATP-dependent helicase SMARCA4(gene name synonym)|uniprotkb:BRG1-associated factor 190A(gene name synonym)|uniprotkb:Protein brahma homolog 1(gene name synonym)|uniprotkb:SNF2-beta(gene name synonym)|uniprotkb:SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Nimura et al. (2009) pubmed:19483677|doi:10.1038/nature08086|imex:IM-21503 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15785002|imex:IM-21503-2|dip:DIP-191745E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-8847927(isoform-parent)|ensembl:ENSMUSG00000057406(gene)|ensembl:ENSMUST00000066854(transcript)|ensembl:ENSMUST00000075812(transcript) refseq:NP_001167549.1|refseq:NP_001167550.1|refseq:NP_035547.2|refseq:XP_006510180.2|refseq:XP_006510182.2|refseq:XP_006510183.2|dip:DIP-40650N|dip:DIP-59249N|ensembl:ENSMUSG00000032187(gene)|ensembl:ENSMUST00000174008(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001188"(RNA polymerase I preinitiation complex assembly)|go:"GO:0001568"(blood vessel development)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001832"(blastocyst growth)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0001889"(liver development)|go:"GO:0002039"(p53 binding)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006346"(DNA methylation-dependent heterochromatin assembly)|go:"GO:0007399"(nervous system development)|go:"GO:0007403"(glial cell fate determination)|go:"GO:0007507"(heart development)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010424"(DNA methylation on cytosine within a CG sequence)|go:"GO:0010467"(gene expression)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0016787"(hydrolase activity)|go:"GO:0022008"(neurogenesis)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030900"(forebrain development)|go:"GO:0030902"(hindbrain development)|go:"GO:0030957"(Tat protein binding)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035887"(aortic smooth muscle cell differentiation)|go:"GO:0035904"(aorta development)|go:"GO:0043044"|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048562"(embryonic organ morphogenesis)|go:"GO:0048730"(epidermis morphogenesis)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060318"(definitive erythrocyte differentiation)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060766"(negative regulation of androgen receptor signaling pathway)|go:"GO:0060976"(coronary vasculature development)|go:"GO:0061626"(pharyngeal arch artery morphogenesis)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0070307"(lens fiber cell development)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0070615"|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:1901838"(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:"GO:1902661"(positive regulation of glucose mediated signaling pathway)|go:"GO:1902895"(positive regulation of miRNA transcription)|interpro:IPR000330(SNF2-related)|interpro:IPR001487(Bromodomain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006576(BRK)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014012(Helicase/SANT-associated, DNA binding)|interpro:IPR014978(QLQ)|interpro:IPR018359|interpro:IPR027417|interpro:IPR029295|interpro:IPR030100|interpro:IPR036427|interpro:IPR038718|mint:Q3TKT4|reactome:R-MMU-1266695|reactome:R-MMU-201722|reactome:R-MMU-3214858|reactome:R-MMU-3247509|reactome:R-MMU-8939243|interpro:IPR037259 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse)|taxid:10090(Mus musculus) - 2017/08/06 2017/08/10 rogid:Nw5cKBOX5XzUL7yM1BqRSAMGLMk10090 rogid:uLQrygmWWugY//OpA2aX4t2VgmM10090 rigid:c//9xafcTuugxIK0mZYZxUCm2f4 false tandem tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P42582 uniprotkb:Q8BVE8-2 intact:EBI-297021|ensembl:ENSMUSP00000015723|uniprotkb:P97335 intact:EBI-11518042|ensembl:ENSMUSP00000067205|ensembl:ENSMUSP00000075210 psi-mi:nkx25_mouse(display_long)|uniprotkb:Nkx2-5(gene name)|psi-mi:Nkx2-5(display_short)|uniprotkb:Csx(gene name synonym)|uniprotkb:Nkx-2.5(gene name synonym)|uniprotkb:Nkx2e(gene name synonym)|uniprotkb:Homeobox protein NK-2 homolog E(gene name synonym)|uniprotkb:Cardiac-specific homeobox(gene name synonym)|uniprotkb:Homeobox protein CSX(gene name synonym) psi-mi:q8bve8-2(display_long)|uniprotkb:Kiaa1090(gene name synonym)|uniprotkb:Nsd2(gene name)|psi-mi:Nsd2(display_short)|uniprotkb:Whsc1(gene name synonym)|uniprotkb:Multiple myeloma SET domain-containing protein(gene name synonym)|uniprotkb:Nuclear SET domain-containing protein 2(gene name synonym)|uniprotkb:Wolf-Hirschhorn syndrome candidate 1 protein homolog(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Nimura et al. (2009) pubmed:19483677|doi:10.1038/nature08086|imex:IM-21503 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15785137|imex:IM-21503-8|dip:DIP-191750E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048536"(spleen development)|go:"GO:0048738"(cardiac muscle tissue development)|go:"GO:0051891"(positive regulation of cardioblast differentiation)|go:"GO:0055005"(ventricular cardiac myofibril assembly)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055014"(atrial cardiac muscle cell development)|go:"GO:0055015"(ventricular cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060037"(pharyngeal system development)|go:"GO:0060038"(cardiac muscle cell proliferation)|go:"GO:0060043"(regulation of cardiac muscle cell proliferation)|go:"GO:0060047"(heart contraction)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060412"(ventricular septum morphogenesis)|go:"GO:0060413"(atrial septum morphogenesis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0060928"(atrioventricular node cell development)|go:"GO:0060929"(atrioventricular node cell fate commitment)|go:"GO:0060971"(embryonic heart tube left/right pattern formation)|go:"GO:0072359"(circulatory system development)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1903779"(regulation of cardiac conduction)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR033629|rcsb pdb:5FLV|ensembl:ENSMUSG00000015579(gene)|ensembl:ENSMUST00000015723(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001947"(heart looping)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003148"(outflow tract septum morphogenesis)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0003162"(atrioventricular node development)|go:"GO:0003166"(bundle of His development)|go:"GO:0003168"(Purkinje myocyte differentiation)|go:"GO:0003208"(cardiac ventricle morphogenesis)|go:"GO:0003211"(cardiac ventricle formation)|go:"GO:0003221"(right ventricular cardiac muscle tissue morphogenesis)|go:"GO:0003222"(ventricular trabecula myocardium morphogenesis)|go:"GO:0003228"(atrial cardiac muscle tissue development)|go:"GO:0003278"(apoptotic process involved in heart morphogenesis)|go:"GO:0003285"(septum secundum development)|go:"GO:0003342"(proepicardium development)|go:"GO:0003350"(pulmonary myocardium development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0003161"(cardiac conduction system development)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007492"(endoderm development)|go:"GO:0007507"(heart development)|go:"GO:0007512"(adult heart development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010667"(negative regulation of cardiac muscle cell apoptotic process)|go:"GO:0010735"(positive regulation of transcription via serum response element binding)|go:"GO:0010765"(positive regulation of sodium ion transport)|go:"GO:0010832"(negative regulation of myotube differentiation)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0030878"(thyroid gland development)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0035050"(embryonic heart tube development)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043586"(tongue development)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045823"(positive regulation of heart contraction)|refseq:NP_032726.1|refseq:XP_006523860.1|dip:DIP-33031N intact:EBI-8847927(isoform-parent)|ensembl:ENSMUSG00000057406(gene)|ensembl:ENSMUST00000066854(transcript)|ensembl:ENSMUST00000075812(transcript) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse)|taxid:10090(Mus musculus) - 2017/08/06 2017/08/10 rogid:/U1x7rZvb4/qIpJkF1tQMZ0UF7A10090 rogid:Nw5cKBOX5XzUL7yM1BqRSAMGLMk10090 rigid:PWjs0SXPKPFVP/yLB5IaKTM8UYk false ha tag:n-n flag tag:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P42582 uniprotkb:Q8BVE8 intact:EBI-297021|ensembl:ENSMUSP00000015723|uniprotkb:P97335 intact:EBI-8847927|uniprotkb:B3VCH6|uniprotkb:Q6ZPY1|uniprotkb:Q7TSF5|uniprotkb:Q811F0|ensembl:ENSMUSP00000058940 psi-mi:nkx25_mouse(display_long)|uniprotkb:Nkx2-5(gene name)|psi-mi:Nkx2-5(display_short)|uniprotkb:Csx(gene name synonym)|uniprotkb:Nkx-2.5(gene name synonym)|uniprotkb:Nkx2e(gene name synonym)|uniprotkb:Homeobox protein NK-2 homolog E(gene name synonym)|uniprotkb:Cardiac-specific homeobox(gene name synonym)|uniprotkb:Homeobox protein CSX(gene name synonym) psi-mi:nsd2_mouse(display_long)|uniprotkb:Nsd2(gene name)|psi-mi:Nsd2(display_short)|uniprotkb:Kiaa1090(gene name synonym)|uniprotkb:Multiple myeloma SET domain-containing protein(gene name synonym)|uniprotkb:Nuclear SET domain-containing protein 2(gene name synonym)|uniprotkb:Whsc1(gene name synonym)|uniprotkb:Wolf-Hirschhorn syndrome candidate 1 protein homolog(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Nimura et al. (2009) pubmed:19483677|doi:10.1038/nature08086|imex:IM-21503 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15785120|imex:IM-21503-7|dip:DIP-191750E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048536"(spleen development)|go:"GO:0048738"(cardiac muscle tissue development)|go:"GO:0051891"(positive regulation of cardioblast differentiation)|go:"GO:0055005"(ventricular cardiac myofibril assembly)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055014"(atrial cardiac muscle cell development)|go:"GO:0055015"(ventricular cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060037"(pharyngeal system development)|go:"GO:0060038"(cardiac muscle cell proliferation)|go:"GO:0060043"(regulation of cardiac muscle cell proliferation)|go:"GO:0060047"(heart contraction)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060412"(ventricular septum morphogenesis)|go:"GO:0060413"(atrial septum morphogenesis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0060928"(atrioventricular node cell development)|go:"GO:0060929"(atrioventricular node cell fate commitment)|go:"GO:0060971"(embryonic heart tube left/right pattern formation)|go:"GO:0072359"(circulatory system development)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1903779"(regulation of cardiac conduction)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR033629|rcsb pdb:5FLV|ensembl:ENSMUSG00000015579(gene)|ensembl:ENSMUST00000015723(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001947"(heart looping)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003148"(outflow tract septum morphogenesis)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0003162"(atrioventricular node development)|go:"GO:0003166"(bundle of His development)|go:"GO:0003168"(Purkinje myocyte differentiation)|go:"GO:0003208"(cardiac ventricle morphogenesis)|go:"GO:0003211"(cardiac ventricle formation)|go:"GO:0003221"(right ventricular cardiac muscle tissue morphogenesis)|go:"GO:0003222"(ventricular trabecula myocardium morphogenesis)|go:"GO:0003228"(atrial cardiac muscle tissue development)|go:"GO:0003278"(apoptotic process involved in heart morphogenesis)|go:"GO:0003285"(septum secundum development)|go:"GO:0003342"(proepicardium development)|go:"GO:0003350"(pulmonary myocardium development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0003161"(cardiac conduction system development)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007492"(endoderm development)|go:"GO:0007507"(heart development)|go:"GO:0007512"(adult heart development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010667"(negative regulation of cardiac muscle cell apoptotic process)|go:"GO:0010735"(positive regulation of transcription via serum response element binding)|go:"GO:0010765"(positive regulation of sodium ion transport)|go:"GO:0010832"(negative regulation of myotube differentiation)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0030878"(thyroid gland development)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0035050"(embryonic heart tube development)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043586"(tongue development)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045823"(positive regulation of heart contraction)|refseq:NP_032726.1|refseq:XP_006523860.1|dip:DIP-33031N refseq:XP_017176079.1|refseq:NP_001074571.2|refseq:NP_780440.2|refseq:XP_006503721.1|refseq:XP_006503722.1|refseq:XP_006503723.1|dip:DIP-60452N|ensembl:ENSMUSG00000057406(gene)|ensembl:ENSMUST00000058096(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0003149"(membranous septum morphogenesis)|go:"GO:0003289"(atrial septum primum morphogenesis)|go:"GO:0003290"(atrial septum secundum morphogenesis)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0010452"(histone H3-K36 methylation)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0034770"(histone H4-K20 methylation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0046975"("histone methyltransferase activity (H3-K36 specific)")|go:"GO:0048298"(positive regulation of isotype switching to IgA isotypes)|go:"GO:0060348"(bone development)|go:"GO:0070201"(regulation of establishment of protein localization)|interpro:IPR000313(PWWP)|interpro:IPR001214(SET)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR006560(AWS)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036910|interpro:IPR041306|mint:Q8BVE8|reactome:R-MMU-3214841|reactome:R-MMU-5693565|reactome:R-MMU-5693571|reactome:R-MMU-5693607|reactome:R-MMU-69473|go:"GO:2001032"(regulation of double-strand break repair via nonhomologous end joining) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse)|taxid:10090(Mus musculus) - 2017/08/06 2017/08/10 rogid:/U1x7rZvb4/qIpJkF1tQMZ0UF7A10090 rogid:cL84Mkvlu++GafQarYkA2Yf8lvc10090 rigid:T7PrOaNIkItKW4oEcg8lc9Ipl9M false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8BVE8 uniprotkb:O09106 intact:EBI-8847927|uniprotkb:B3VCH6|uniprotkb:Q6ZPY1|uniprotkb:Q7TSF5|uniprotkb:Q811F0|ensembl:ENSMUSP00000058940 intact:EBI-301912|uniprotkb:P97476|ensembl:ENSMUSP00000099657 psi-mi:nsd2_mouse(display_long)|uniprotkb:Nsd2(gene name)|psi-mi:Nsd2(display_short)|uniprotkb:Kiaa1090(gene name synonym)|uniprotkb:Multiple myeloma SET domain-containing protein(gene name synonym)|uniprotkb:Nuclear SET domain-containing protein 2(gene name synonym)|uniprotkb:Whsc1(gene name synonym)|uniprotkb:Wolf-Hirschhorn syndrome candidate 1 protein homolog(gene name synonym) psi-mi:hdac1_mouse(display_long)|uniprotkb:Hdac1(gene name)|psi-mi:Hdac1(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Nimura et al. (2009) pubmed:19483677|doi:10.1038/nature08086|imex:IM-21503 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15785101|imex:IM-21503-6|dip:DIP-191749E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_017176079.1|refseq:NP_001074571.2|refseq:NP_780440.2|refseq:XP_006503721.1|refseq:XP_006503722.1|refseq:XP_006503723.1|dip:DIP-60452N|ensembl:ENSMUSG00000057406(gene)|ensembl:ENSMUST00000058096(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0003149"(membranous septum morphogenesis)|go:"GO:0003289"(atrial septum primum morphogenesis)|go:"GO:0003290"(atrial septum secundum morphogenesis)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0010452"(histone H3-K36 methylation)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0034770"(histone H4-K20 methylation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0046975"("histone methyltransferase activity (H3-K36 specific)")|go:"GO:0048298"(positive regulation of isotype switching to IgA isotypes)|go:"GO:0060348"(bone development)|go:"GO:0070201"(regulation of establishment of protein localization)|interpro:IPR000313(PWWP)|interpro:IPR001214(SET)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR006560(AWS)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036910|interpro:IPR041306|mint:Q8BVE8|reactome:R-MMU-3214841|reactome:R-MMU-5693565|reactome:R-MMU-5693571|reactome:R-MMU-5693607|reactome:R-MMU-69473|go:"GO:2001032"(regulation of double-strand break repair via nonhomologous end joining) dip:DIP-31499N|ensembl:ENSMUSG00000028800(gene)|ensembl:ENSMUST00000102597(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|refseq:NP_032254.1|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0052548"(regulation of endopeptidase activity)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0060766"(negative regulation of androgen receptor signaling pathway)|go:"GO:0060789"(hair follicle placode formation)|go:"GO:0061029"(eyelid development in camera-type eye)|go:"GO:0061198"(fungiform papilla formation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070888"(E-box binding)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000273"(positive regulation of signaling receptor activity)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000757"(negative regulation of peptidyl-lysine acetylation)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|mint:O09106|reactome:R-MMU-1538133|reactome:R-MMU-201722|reactome:R-MMU-2173795|reactome:R-MMU-3214815|reactome:R-MMU-350054|reactome:R-MMU-3769402|reactome:R-MMU-4551638|reactome:R-MMU-6804758|reactome:R-MMU-73762|reactome:R-MMU-8936459|reactome:R-MMU-8943724|reactome:R-MMU-9018519|reactome:R-MMU-9022692|reactome:R-MMU-983231|go:"GO:2000676"(positive regulation of type B pancreatic cell apoptotic process)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019213"(deacetylase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0021766"(hippocampus development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031000"(response to caffeine)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032732"(positive regulation of interleukin-1 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035851"(Krueppel-associated box domain binding)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042493"|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0001975"(response to amphetamine)|go:"GO:0002039"(p53 binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006346"(DNA methylation-dependent heterochromatin assembly)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006476"(protein deacetylation)|go:"GO:0007492"(endoderm development)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009913"(epidermal cell differentiation)|go:"GO:0001046"(core promoter sequence-specific DNA binding) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse)|taxid:10090(Mus musculus) - 2017/08/06 2017/08/10 rogid:cL84Mkvlu++GafQarYkA2Yf8lvc10090 rogid:P7QV++FiMiNcabUkswbnNhGVU3410090 rigid:/kVlErtiLL50rqgwROxbrUd4aPE false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8BVE8 uniprotkb:Q80Z64 intact:EBI-8847927|uniprotkb:B3VCH6|uniprotkb:Q6ZPY1|uniprotkb:Q7TSF5|uniprotkb:Q811F0|ensembl:ENSMUSP00000058940 intact:EBI-2312517|uniprotkb:Q6SMR1|uniprotkb:Q7TN85|ensembl:ENSMUSP00000012540 psi-mi:nsd2_mouse(display_long)|uniprotkb:Nsd2(gene name)|psi-mi:Nsd2(display_short)|uniprotkb:Kiaa1090(gene name synonym)|uniprotkb:Multiple myeloma SET domain-containing protein(gene name synonym)|uniprotkb:Nuclear SET domain-containing protein 2(gene name synonym)|uniprotkb:Whsc1(gene name synonym)|uniprotkb:Wolf-Hirschhorn syndrome candidate 1 protein homolog(gene name synonym) psi-mi:nanog_mouse(display_long)|uniprotkb:Nanog(gene name)|psi-mi:Nanog(display_short)|uniprotkb:Ecat4(gene name synonym)|uniprotkb:Enk(gene name synonym)|uniprotkb:Homeobox transcription factor Nanog(gene name synonym)|uniprotkb:Early embryo specific expression NK-type homeobox protein(gene name synonym)|uniprotkb:ES cell-associated protein 4(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Nimura et al. (2009) pubmed:19483677|doi:10.1038/nature08086|imex:IM-21503 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15785101|imex:IM-21503-6|dip:DIP-191749E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_017176079.1|refseq:NP_001074571.2|refseq:NP_780440.2|refseq:XP_006503721.1|refseq:XP_006503722.1|refseq:XP_006503723.1|dip:DIP-60452N|ensembl:ENSMUSG00000057406(gene)|ensembl:ENSMUST00000058096(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0003149"(membranous septum morphogenesis)|go:"GO:0003289"(atrial septum primum morphogenesis)|go:"GO:0003290"(atrial septum secundum morphogenesis)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0010452"(histone H3-K36 methylation)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0034770"(histone H4-K20 methylation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0046975"("histone methyltransferase activity (H3-K36 specific)")|go:"GO:0048298"(positive regulation of isotype switching to IgA isotypes)|go:"GO:0060348"(bone development)|go:"GO:0070201"(regulation of establishment of protein localization)|interpro:IPR000313(PWWP)|interpro:IPR001214(SET)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR006560(AWS)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036910|interpro:IPR041306|mint:Q8BVE8|reactome:R-MMU-3214841|reactome:R-MMU-5693565|reactome:R-MMU-5693571|reactome:R-MMU-5693607|reactome:R-MMU-69473|go:"GO:2001032"(regulation of double-strand break repair via nonhomologous end joining) refseq:NP_001276757.1|refseq:NP_001276759.1|refseq:NP_001276760.1|refseq:NP_082292.1|refseq:XP_006506714.1|dip:DIP-29932N|ensembl:ENSMUSG00000012396(gene)|ensembl:ENSMUST00000012540(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001010"(RNA polymerase II sequence-specific DNA-binding transcription factor recruiting activity)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001710"(mesodermal cell fate commitment)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008406"(gonad development)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0010033"(response to organic substance)|go:"GO:0010454"(negative regulation of cell fate commitment)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0017145"(stem cell division)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0042664"(negative regulation of endodermal cell fate specification)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043697"(cell dedifferentiation)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048863"(stem cell differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000035"(regulation of stem cell division)|go:"GO:2000648"(positive regulation of stem cell proliferation)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|mint:Q80Z64|rcsb pdb:2VI6 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse)|taxid:10090(Mus musculus) - 2017/08/06 2017/08/10 rogid:cL84Mkvlu++GafQarYkA2Yf8lvc10090 rogid:v8TDhd7PZnOKFS3djxouMHxftPs10090 rigid:/kVlErtiLL50rqgwROxbrUd4aPE false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8BVE8 uniprotkb:Q9ER74 intact:EBI-8847927|uniprotkb:B3VCH6|uniprotkb:Q6ZPY1|uniprotkb:Q7TSF5|uniprotkb:Q811F0|ensembl:ENSMUSP00000058940 intact:EBI-2312562|uniprotkb:Q920R5 psi-mi:nsd2_mouse(display_long)|uniprotkb:Nsd2(gene name)|psi-mi:Nsd2(display_short)|uniprotkb:Kiaa1090(gene name synonym)|uniprotkb:Multiple myeloma SET domain-containing protein(gene name synonym)|uniprotkb:Nuclear SET domain-containing protein 2(gene name synonym)|uniprotkb:Whsc1(gene name synonym)|uniprotkb:Wolf-Hirschhorn syndrome candidate 1 protein homolog(gene name synonym) psi-mi:sall1_mouse(display_long)|uniprotkb:Sall1(gene name)|psi-mi:Sall1(display_short)|uniprotkb:Sal3(gene name synonym)|uniprotkb:Zinc finger protein Spalt-3(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Nimura et al. (2009) pubmed:19483677|doi:10.1038/nature08086|imex:IM-21503 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15785101|imex:IM-21503-6|dip:DIP-191749E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_017176079.1|refseq:NP_001074571.2|refseq:NP_780440.2|refseq:XP_006503721.1|refseq:XP_006503722.1|refseq:XP_006503723.1|dip:DIP-60452N|ensembl:ENSMUSG00000057406(gene)|ensembl:ENSMUST00000058096(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0003149"(membranous septum morphogenesis)|go:"GO:0003289"(atrial septum primum morphogenesis)|go:"GO:0003290"(atrial septum secundum morphogenesis)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0010452"(histone H3-K36 methylation)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0034770"(histone H4-K20 methylation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0046975"("histone methyltransferase activity (H3-K36 specific)")|go:"GO:0048298"(positive regulation of isotype switching to IgA isotypes)|go:"GO:0060348"(bone development)|go:"GO:0070201"(regulation of establishment of protein localization)|interpro:IPR000313(PWWP)|interpro:IPR001214(SET)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR006560(AWS)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036910|interpro:IPR041306|mint:Q8BVE8|reactome:R-MMU-3214841|reactome:R-MMU-5693565|reactome:R-MMU-5693571|reactome:R-MMU-5693607|reactome:R-MMU-69473|go:"GO:2001032"(regulation of double-strand break repair via nonhomologous end joining) dip:DIP-54906N|go:"GO:0021553"(olfactory nerve development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0021889"(olfactory bulb interneuron differentiation)|go:"GO:0021915"(neural tube development)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0031129"(inductive cell-cell signaling)|go:"GO:0035136"(forelimb morphogenesis)|go:"GO:0035137"(hindlimb morphogenesis)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048566"(embryonic digestive tract development)|go:"GO:0001657"(ureteric bud development)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001822"(kidney development)|go:"GO:0001843"(neural tube closure)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003337"(mesenchymal to epithelial transition involved in metanephros morphogenesis)|go:"GO:0003340"(negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007507"(heart development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0010369"(chromocenter)|go:"GO:0016581"(NuRD complex)|go:"GO:0060173"(limb development)|go:"GO:0061034"(olfactory bulb mitral cell layer development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0072073"(kidney epithelium development)|go:"GO:0072092"(ureteric bud invasion)|go:"GO:0072309"(mesenchymal stem cell maintenance involved in metanephric nephron morphogenesis)|go:"GO:0090190"(positive regulation of branching involved in ureteric bud morphogenesis)|go:"GO:2000177"(regulation of neural precursor cell proliferation)|go:"GO:2000381"(negative regulation of mesoderm development)|go:"GO:2000384"(negative regulation of ectoderm development)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000792"(heterochromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse)|taxid:10090(Mus musculus) - 2017/08/06 2017/08/10 rogid:cL84Mkvlu++GafQarYkA2Yf8lvc10090 rogid:Izbkv4nqxte6ww3HvP4XCCueQGg10090 rigid:/kVlErtiLL50rqgwROxbrUd4aPE false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8BX22 uniprotkb:Q8BVE8-2 intact:EBI-2312582|uniprotkb:A2AV00|uniprotkb:Q6S7E8|uniprotkb:Q6S7E9|uniprotkb:Q7TST6|ensembl:ENSMUSP00000029061 intact:EBI-11518042|ensembl:ENSMUSP00000067205|ensembl:ENSMUSP00000075210 psi-mi:sall4_mouse(display_long)|uniprotkb:Sall4(gene name)|psi-mi:Sall4(display_short)|uniprotkb:Zinc finger protein SALL4(gene name synonym) psi-mi:q8bve8-2(display_long)|uniprotkb:Kiaa1090(gene name synonym)|uniprotkb:Nsd2(gene name)|psi-mi:Nsd2(display_short)|uniprotkb:Whsc1(gene name synonym)|uniprotkb:Multiple myeloma SET domain-containing protein(gene name synonym)|uniprotkb:Nuclear SET domain-containing protein 2(gene name synonym)|uniprotkb:Wolf-Hirschhorn syndrome candidate 1 protein homolog(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Nimura et al. (2009) pubmed:19483677|doi:10.1038/nature08086|imex:IM-21503 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15785078|imex:IM-21503-5|dip:DIP-191746E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_780512.2|refseq:NP_958797.2|refseq:NP_958798.2|dip:DIP-29926N|ensembl:ENSMUSG00000027547(gene)|ensembl:ENSMUST00000029061(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000792"(heterochromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001833"(inner cell mass cell proliferation)|go:"GO:0001843"(neural tube closure)|go:"GO:0003281"(ventricular septum development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009888"(tissue development)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021915"(neural tube development)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q8BX22|reactome:R-MMU-8943724 intact:EBI-8847927(isoform-parent)|ensembl:ENSMUSG00000057406(gene)|ensembl:ENSMUST00000066854(transcript)|ensembl:ENSMUST00000075812(transcript) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse)|taxid:10090(Mus musculus) - 2017/08/06 2017/08/10 rogid:84RTcgupqeb0ypojGiwpAezUWVw10090 rogid:Nw5cKBOX5XzUL7yM1BqRSAMGLMk10090 rigid:pYWAlTWD26pwQ5/md19W+FFaOdg false - flag tag:?-?|sufficient binding region:453-521 - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8BVE8-2 uniprotkb:Q80Z64 intact:EBI-11518042|ensembl:ENSMUSP00000067205|ensembl:ENSMUSP00000075210 intact:EBI-2312517|uniprotkb:Q6SMR1|uniprotkb:Q7TN85|ensembl:ENSMUSP00000012540 psi-mi:q8bve8-2(display_long)|uniprotkb:Kiaa1090(gene name synonym)|uniprotkb:Nsd2(gene name)|psi-mi:Nsd2(display_short)|uniprotkb:Whsc1(gene name synonym)|uniprotkb:Multiple myeloma SET domain-containing protein(gene name synonym)|uniprotkb:Nuclear SET domain-containing protein 2(gene name synonym)|uniprotkb:Wolf-Hirschhorn syndrome candidate 1 protein homolog(gene name synonym) psi-mi:nanog_mouse(display_long)|uniprotkb:Nanog(gene name)|psi-mi:Nanog(display_short)|uniprotkb:Ecat4(gene name synonym)|uniprotkb:Enk(gene name synonym)|uniprotkb:Homeobox transcription factor Nanog(gene name synonym)|uniprotkb:Early embryo specific expression NK-type homeobox protein(gene name synonym)|uniprotkb:ES cell-associated protein 4(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Nimura et al. (2009) pubmed:19483677|doi:10.1038/nature08086|imex:IM-21503 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15785160|imex:IM-21503-9|dip:DIP-191747E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-8847927(isoform-parent)|ensembl:ENSMUSG00000057406(gene)|ensembl:ENSMUST00000066854(transcript)|ensembl:ENSMUST00000075812(transcript) refseq:NP_001276757.1|refseq:NP_001276759.1|refseq:NP_001276760.1|refseq:NP_082292.1|refseq:XP_006506714.1|dip:DIP-29932N|ensembl:ENSMUSG00000012396(gene)|ensembl:ENSMUST00000012540(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001010"(RNA polymerase II sequence-specific DNA-binding transcription factor recruiting activity)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001710"(mesodermal cell fate commitment)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008406"(gonad development)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0010033"(response to organic substance)|go:"GO:0010454"(negative regulation of cell fate commitment)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0017145"(stem cell division)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0042664"(negative regulation of endodermal cell fate specification)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043697"(cell dedifferentiation)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048863"(stem cell differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000035"(regulation of stem cell division)|go:"GO:2000648"(positive regulation of stem cell proliferation)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|mint:Q80Z64|rcsb pdb:2VI6 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse)|taxid:10090(Mus musculus) - 2017/08/06 2017/08/10 rogid:Nw5cKBOX5XzUL7yM1BqRSAMGLMk10090 rogid:v8TDhd7PZnOKFS3djxouMHxftPs10090 rigid:Xc5k9ZhYnHuA0LFqCA8Bxfg8cRw false flag tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8BVE8-2 uniprotkb:Q9ER74 intact:EBI-11518042|ensembl:ENSMUSP00000067205|ensembl:ENSMUSP00000075210 intact:EBI-2312562|uniprotkb:Q920R5 psi-mi:q8bve8-2(display_long)|uniprotkb:Kiaa1090(gene name synonym)|uniprotkb:Nsd2(gene name)|psi-mi:Nsd2(display_short)|uniprotkb:Whsc1(gene name synonym)|uniprotkb:Multiple myeloma SET domain-containing protein(gene name synonym)|uniprotkb:Nuclear SET domain-containing protein 2(gene name synonym)|uniprotkb:Wolf-Hirschhorn syndrome candidate 1 protein homolog(gene name synonym) psi-mi:sall1_mouse(display_long)|uniprotkb:Sall1(gene name)|psi-mi:Sall1(display_short)|uniprotkb:Sal3(gene name synonym)|uniprotkb:Zinc finger protein Spalt-3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Nimura et al. (2009) pubmed:19483677|doi:10.1038/nature08086|imex:IM-21503 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15785160|imex:IM-21503-9|dip:DIP-191747E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-8847927(isoform-parent)|ensembl:ENSMUSG00000057406(gene)|ensembl:ENSMUST00000066854(transcript)|ensembl:ENSMUST00000075812(transcript) dip:DIP-54906N|go:"GO:0021553"(olfactory nerve development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0021889"(olfactory bulb interneuron differentiation)|go:"GO:0021915"(neural tube development)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0031129"(inductive cell-cell signaling)|go:"GO:0035136"(forelimb morphogenesis)|go:"GO:0035137"(hindlimb morphogenesis)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048566"(embryonic digestive tract development)|go:"GO:0001657"(ureteric bud development)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001822"(kidney development)|go:"GO:0001843"(neural tube closure)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003337"(mesenchymal to epithelial transition involved in metanephros morphogenesis)|go:"GO:0003340"(negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007507"(heart development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0010369"(chromocenter)|go:"GO:0016581"(NuRD complex)|go:"GO:0060173"(limb development)|go:"GO:0061034"(olfactory bulb mitral cell layer development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0072073"(kidney epithelium development)|go:"GO:0072092"(ureteric bud invasion)|go:"GO:0072309"(mesenchymal stem cell maintenance involved in metanephric nephron morphogenesis)|go:"GO:0090190"(positive regulation of branching involved in ureteric bud morphogenesis)|go:"GO:2000177"(regulation of neural precursor cell proliferation)|go:"GO:2000381"(negative regulation of mesoderm development)|go:"GO:2000384"(negative regulation of ectoderm development)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000792"(heterochromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse)|taxid:10090(Mus musculus) - 2017/08/06 2017/08/10 rogid:Nw5cKBOX5XzUL7yM1BqRSAMGLMk10090 rogid:Izbkv4nqxte6ww3HvP4XCCueQGg10090 rigid:Xc5k9ZhYnHuA0LFqCA8Bxfg8cRw false flag tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)