#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q8U1R4	uniprotkb:Q8U160	intact:EBI-9025188|ensemblbacteria:AAL81265	intact:EBI-15599230|ensemblbacteria:AAL81491	psi-mi:nop10_pyrfu(display_long)|uniprotkb:nop10(gene name)|psi-mi:nop10(display_short)|uniprotkb:PF1141(locus name)	psi-mi:rl7a_pyrfu(display_long)|uniprotkb:Ribosomal protein L8e(gene name synonym)|uniprotkb:PF1367(locus name)|uniprotkb:rpl7ae(gene name)|psi-mi:rpl7ae(display_short)|uniprotkb:Large ribosomal subunit protein eL8(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Liang et al. (2009)	pubmed:19478803|doi:10.1038/nsmb.1624|imex:IM-14281	taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus)	taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15784507|imex:IM-14281-1|dip:DIP-103089E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:WP_011012281.1|dip:DIP-48527N|ensemblbacteria:AAL81265(transcript)|ensemblbacteria:PF1141(gene)|go:"GO:0001522"(pseudouridine synthesis)|go:"GO:0006364"(rRNA processing)|go:"GO:0030515"(snoRNA binding)|interpro:IPR007264(Nucleolar RNA-binding protein Nop10p)|interpro:IPR023532|interpro:IPR036756|rcsb pdb:2EY4|rcsb pdb:2HVY|rcsb pdb:2RFK|rcsb pdb:3HAX|rcsb pdb:3HAY|rcsb pdb:3HJW|rcsb pdb:3HJY|rcsb pdb:3LWO|rcsb pdb:3LWP|rcsb pdb:3LWQ|rcsb pdb:3LWR|rcsb pdb:3LWV|rcsb pdb:3MQK	ensemblbacteria:AAL81491(transcript)|ensemblbacteria:PF1367(gene)|go:"GO:0001682"(tRNA 5'-leader removal)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0004526"(ribonuclease P activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005840"(ribosome)|go:"GO:0006364"(rRNA processing)|go:"GO:0019843"(rRNA binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000948(Ribosomal protein HS6)|interpro:IPR004037(Ribosomal protein L7Ae)|interpro:IPR004038(Ribosomal protein L7Ae/L30e/S12e/Gadd45)|interpro:IPR018492|interpro:IPR022481|interpro:IPR029064|rcsb pdb:2HVY|rcsb pdb:3HAX|rcsb pdb:3HAY|rcsb pdb:3HJW|rcsb pdb:3LWO|rcsb pdb:3LWP|rcsb pdb:3LWQ|rcsb pdb:3LWR|rcsb pdb:3LWV|rcsb pdb:3NMU|rcsb pdb:3NVI|rcsb pdb:3NVK|rcsb pdb:4BY9|rcsb pdb:4V4N|rcsb pdb:4V6U|rcsb pdb:5JB3|go:"GO:0006412"(translation)|rcsb pdb:5JBH|rcsb pdb:6TPH|refseq:WP_014835393.1|dip:DIP-48528N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/06	2017/08/10	rogid:o0iTRobDd9r9Azo1hfSEMRMK6JM186497	rogid:M1LmNnXAwFfbCEFfnNljmYEzdsU186497	rigid:dV31OyZ29OWhM4kMTvbZn99v5MI	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8U1R4	uniprotkb:Q7LWY0	intact:EBI-9025188|ensemblbacteria:AAL81265	intact:EBI-9025178|ensemblbacteria:AAL81909	psi-mi:nop10_pyrfu(display_long)|uniprotkb:nop10(gene name)|psi-mi:nop10(display_short)|uniprotkb:PF1141(locus name)	psi-mi:trub_pyrfu(display_long)|uniprotkb:truB(gene name)|psi-mi:truB(display_short)|uniprotkb:"tRNA pseudouridine(55) synthase"(gene name synonym)|uniprotkb:tRNA pseudouridylate synthase(gene name synonym)|uniprotkb:tRNA-uridine isomerase(gene name synonym)|uniprotkb:PF1785(locus name)	psi-mi:"MI:0114"(x-ray crystallography)	Liang et al. (2009)	pubmed:19478803|doi:10.1038/nsmb.1624|imex:IM-14281	taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus)	taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15784507|imex:IM-14281-1|dip:DIP-103089E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:WP_011012281.1|dip:DIP-48527N|ensemblbacteria:AAL81265(transcript)|ensemblbacteria:PF1141(gene)|go:"GO:0001522"(pseudouridine synthesis)|go:"GO:0006364"(rRNA processing)|go:"GO:0030515"(snoRNA binding)|interpro:IPR007264(Nucleolar RNA-binding protein Nop10p)|interpro:IPR023532|interpro:IPR036756|rcsb pdb:2EY4|rcsb pdb:2HVY|rcsb pdb:2RFK|rcsb pdb:3HAX|rcsb pdb:3HAY|rcsb pdb:3HJW|rcsb pdb:3HJY|rcsb pdb:3LWO|rcsb pdb:3LWP|rcsb pdb:3LWQ|rcsb pdb:3LWR|rcsb pdb:3LWV|rcsb pdb:3MQK	refseq:WP_011012926.1|dip:DIP-48526N|ensemblbacteria:AAL81909(transcript)|ensemblbacteria:PF1785(gene)|go:"GO:0003723"(RNA binding)|go:"GO:0031119"(tRNA pseudouridine synthesis)|go:"GO:0106029"(tRNA pseudouridine synthase activity)|interpro:IPR002478(PUA)|interpro:IPR002501(tRNA pseudouridine synthase B, N-terminal)|interpro:IPR004521(Uncharacterized domain 2)|interpro:IPR004802(Putative rRNA pseudouridine synthase)|interpro:IPR012960(DKCLD)|interpro:IPR015947(PUA-like)|interpro:IPR020103|interpro:IPR026326|interpro:IPR032819|interpro:IPR036974|rcsb pdb:2EY4|rcsb pdb:2HVY|rcsb pdb:2RFK|rcsb pdb:3HAX|rcsb pdb:3HAY|rcsb pdb:3HJW|rcsb pdb:3HJY|rcsb pdb:3LWO|rcsb pdb:3LWP|rcsb pdb:3LWQ|rcsb pdb:3LWR|rcsb pdb:3LWV|rcsb pdb:3MQK	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/06	2017/08/10	rogid:o0iTRobDd9r9Azo1hfSEMRMK6JM186497	rogid:50ywZVQB/ed+unwOolj7upl0ucI186497	rigid:dV31OyZ29OWhM4kMTvbZn99v5MI	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8U1R4	uniprotkb:Q7LWY0	intact:EBI-9025188|ensemblbacteria:AAL81265	intact:EBI-9025178|ensemblbacteria:AAL81909	psi-mi:nop10_pyrfu(display_long)|uniprotkb:nop10(gene name)|psi-mi:nop10(display_short)|uniprotkb:PF1141(locus name)	psi-mi:trub_pyrfu(display_long)|uniprotkb:truB(gene name)|psi-mi:truB(display_short)|uniprotkb:"tRNA pseudouridine(55) synthase"(gene name synonym)|uniprotkb:tRNA pseudouridylate synthase(gene name synonym)|uniprotkb:tRNA-uridine isomerase(gene name synonym)|uniprotkb:PF1785(locus name)	psi-mi:"MI:0096"(pull down)	Liang et al. (2009)	pubmed:19478803|doi:10.1038/nsmb.1624|imex:IM-14281	taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus)	taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15784525|imex:IM-14281-2|dip:DIP-103090E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:WP_011012281.1|dip:DIP-48527N|ensemblbacteria:AAL81265(transcript)|ensemblbacteria:PF1141(gene)|go:"GO:0001522"(pseudouridine synthesis)|go:"GO:0006364"(rRNA processing)|go:"GO:0030515"(snoRNA binding)|interpro:IPR007264(Nucleolar RNA-binding protein Nop10p)|interpro:IPR023532|interpro:IPR036756|rcsb pdb:2EY4|rcsb pdb:2HVY|rcsb pdb:2RFK|rcsb pdb:3HAX|rcsb pdb:3HAY|rcsb pdb:3HJW|rcsb pdb:3HJY|rcsb pdb:3LWO|rcsb pdb:3LWP|rcsb pdb:3LWQ|rcsb pdb:3LWR|rcsb pdb:3LWV|rcsb pdb:3MQK	refseq:WP_011012926.1|dip:DIP-48526N|ensemblbacteria:AAL81909(transcript)|ensemblbacteria:PF1785(gene)|go:"GO:0003723"(RNA binding)|go:"GO:0031119"(tRNA pseudouridine synthesis)|go:"GO:0106029"(tRNA pseudouridine synthase activity)|interpro:IPR002478(PUA)|interpro:IPR002501(tRNA pseudouridine synthase B, N-terminal)|interpro:IPR004521(Uncharacterized domain 2)|interpro:IPR004802(Putative rRNA pseudouridine synthase)|interpro:IPR012960(DKCLD)|interpro:IPR015947(PUA-like)|interpro:IPR020103|interpro:IPR026326|interpro:IPR032819|interpro:IPR036974|rcsb pdb:2EY4|rcsb pdb:2HVY|rcsb pdb:2RFK|rcsb pdb:3HAX|rcsb pdb:3HAY|rcsb pdb:3HJW|rcsb pdb:3HJY|rcsb pdb:3LWO|rcsb pdb:3LWP|rcsb pdb:3LWQ|rcsb pdb:3LWR|rcsb pdb:3LWV|rcsb pdb:3MQK	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:562(ecolx)|taxid:562(Escherichia coli)	-	2017/08/06	2017/08/10	rogid:o0iTRobDd9r9Azo1hfSEMRMK6JM186497	rogid:50ywZVQB/ed+unwOolj7upl0ucI186497	rigid:FM770Js70Vn4/NRSaM4hNqqbb4Q	false	his tag:n-n	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8U1R4	uniprotkb:Q7LWY0	intact:EBI-9025188|ensemblbacteria:AAL81265	intact:EBI-9025178|ensemblbacteria:AAL81909	psi-mi:nop10_pyrfu(display_long)|uniprotkb:nop10(gene name)|psi-mi:nop10(display_short)|uniprotkb:PF1141(locus name)	psi-mi:trub_pyrfu(display_long)|uniprotkb:truB(gene name)|psi-mi:truB(display_short)|uniprotkb:"tRNA pseudouridine(55) synthase"(gene name synonym)|uniprotkb:tRNA pseudouridylate synthase(gene name synonym)|uniprotkb:tRNA-uridine isomerase(gene name synonym)|uniprotkb:PF1785(locus name)	psi-mi:"MI:0114"(x-ray crystallography)	Liang et al. (2009)	pubmed:19478803|doi:10.1038/nsmb.1624|imex:IM-14281	taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus)	taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15784545|imex:IM-14281-3|dip:DIP-103090E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:WP_011012281.1|dip:DIP-48527N|ensemblbacteria:AAL81265(transcript)|ensemblbacteria:PF1141(gene)|go:"GO:0001522"(pseudouridine synthesis)|go:"GO:0006364"(rRNA processing)|go:"GO:0030515"(snoRNA binding)|interpro:IPR007264(Nucleolar RNA-binding protein Nop10p)|interpro:IPR023532|interpro:IPR036756|rcsb pdb:2EY4|rcsb pdb:2HVY|rcsb pdb:2RFK|rcsb pdb:3HAX|rcsb pdb:3HAY|rcsb pdb:3HJW|rcsb pdb:3HJY|rcsb pdb:3LWO|rcsb pdb:3LWP|rcsb pdb:3LWQ|rcsb pdb:3LWR|rcsb pdb:3LWV|rcsb pdb:3MQK	refseq:WP_011012926.1|dip:DIP-48526N|ensemblbacteria:AAL81909(transcript)|ensemblbacteria:PF1785(gene)|go:"GO:0003723"(RNA binding)|go:"GO:0031119"(tRNA pseudouridine synthesis)|go:"GO:0106029"(tRNA pseudouridine synthase activity)|interpro:IPR002478(PUA)|interpro:IPR002501(tRNA pseudouridine synthase B, N-terminal)|interpro:IPR004521(Uncharacterized domain 2)|interpro:IPR004802(Putative rRNA pseudouridine synthase)|interpro:IPR012960(DKCLD)|interpro:IPR015947(PUA-like)|interpro:IPR020103|interpro:IPR026326|interpro:IPR032819|interpro:IPR036974|rcsb pdb:2EY4|rcsb pdb:2HVY|rcsb pdb:2RFK|rcsb pdb:3HAX|rcsb pdb:3HAY|rcsb pdb:3HJW|rcsb pdb:3HJY|rcsb pdb:3LWO|rcsb pdb:3LWP|rcsb pdb:3LWQ|rcsb pdb:3LWR|rcsb pdb:3LWV|rcsb pdb:3MQK	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:562(ecolx)|taxid:562(Escherichia coli)	-	2017/08/06	2017/08/10	rogid:o0iTRobDd9r9Azo1hfSEMRMK6JM186497	rogid:50ywZVQB/ed+unwOolj7upl0ucI186497	rigid:FM770Js70Vn4/NRSaM4hNqqbb4Q	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8U1R4	uniprotkb:Q7LWY0	intact:EBI-9025188|ensemblbacteria:AAL81265	intact:EBI-9025178|ensemblbacteria:AAL81909	psi-mi:nop10_pyrfu(display_long)|uniprotkb:nop10(gene name)|psi-mi:nop10(display_short)|uniprotkb:PF1141(locus name)	psi-mi:trub_pyrfu(display_long)|uniprotkb:truB(gene name)|psi-mi:truB(display_short)|uniprotkb:"tRNA pseudouridine(55) synthase"(gene name synonym)|uniprotkb:tRNA pseudouridylate synthase(gene name synonym)|uniprotkb:tRNA-uridine isomerase(gene name synonym)|uniprotkb:PF1785(locus name)	psi-mi:"MI:0071"(molecular sieving)	Liang et al. (2009)	pubmed:19478803|doi:10.1038/nsmb.1624|imex:IM-14281	taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus)	taxid:186497(pyrfu)|taxid:186497(Pyrococcus furiosus)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15784562|imex:IM-14281-4|dip:DIP-103090E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:WP_011012281.1|dip:DIP-48527N|ensemblbacteria:AAL81265(transcript)|ensemblbacteria:PF1141(gene)|go:"GO:0001522"(pseudouridine synthesis)|go:"GO:0006364"(rRNA processing)|go:"GO:0030515"(snoRNA binding)|interpro:IPR007264(Nucleolar RNA-binding protein Nop10p)|interpro:IPR023532|interpro:IPR036756|rcsb pdb:2EY4|rcsb pdb:2HVY|rcsb pdb:2RFK|rcsb pdb:3HAX|rcsb pdb:3HAY|rcsb pdb:3HJW|rcsb pdb:3HJY|rcsb pdb:3LWO|rcsb pdb:3LWP|rcsb pdb:3LWQ|rcsb pdb:3LWR|rcsb pdb:3LWV|rcsb pdb:3MQK	refseq:WP_011012926.1|dip:DIP-48526N|ensemblbacteria:AAL81909(transcript)|ensemblbacteria:PF1785(gene)|go:"GO:0003723"(RNA binding)|go:"GO:0031119"(tRNA pseudouridine synthesis)|go:"GO:0106029"(tRNA pseudouridine synthase activity)|interpro:IPR002478(PUA)|interpro:IPR002501(tRNA pseudouridine synthase B, N-terminal)|interpro:IPR004521(Uncharacterized domain 2)|interpro:IPR004802(Putative rRNA pseudouridine synthase)|interpro:IPR012960(DKCLD)|interpro:IPR015947(PUA-like)|interpro:IPR020103|interpro:IPR026326|interpro:IPR032819|interpro:IPR036974|rcsb pdb:2EY4|rcsb pdb:2HVY|rcsb pdb:2RFK|rcsb pdb:3HAX|rcsb pdb:3HAY|rcsb pdb:3HJW|rcsb pdb:3HJY|rcsb pdb:3LWO|rcsb pdb:3LWP|rcsb pdb:3LWQ|rcsb pdb:3LWR|rcsb pdb:3LWV|rcsb pdb:3MQK	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:562(ecolx)|taxid:562(Escherichia coli)	-	2017/08/06	2017/08/10	rogid:o0iTRobDd9r9Azo1hfSEMRMK6JM186497	rogid:50ywZVQB/ed+unwOolj7upl0ucI186497	rigid:FM770Js70Vn4/NRSaM4hNqqbb4Q	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)