#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P72525	uniprotkb:Q59961	intact:EBI-9010147|uniprotkb:P72537|uniprotkb:Q54917|ensemblbacteria:AAK74984	intact:EBI-9010149|uniprotkb:P77956|ensemblbacteria:AAK74981	psi-mi:parc_strpn(display_long)|uniprotkb:parC(gene name)|psi-mi:parC(display_short)|uniprotkb:Topoisomerase IV subunit A(gene name synonym)|uniprotkb:SP_0855(locus name)	psi-mi:pare_strpn(display_long)|uniprotkb:parE(gene name)|psi-mi:parE(display_short)|uniprotkb:Topoisomerase IV subunit B(gene name synonym)|uniprotkb:SP_0852(locus name)	psi-mi:"MI:0114"(x-ray crystallography)	Laponogov et al. (2009)	pubmed:19448616|doi:10.1038/nsmb.1604|imex:IM-14276	taxid:170187(strpn)|taxid:170187("Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4)")	taxid:170187(strpn)|taxid:170187("Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15781382|imex:IM-14276-1|dip:DIP-103080E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-48521N|ensemblbacteria:AAK74984(transcript)|ensemblbacteria:SP_0855(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003918"("DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005694"(chromosome)|go:"GO:0006265"(DNA topological change)|go:"GO:0007059"(chromosome segregation)|go:"GO:0019897"(extrinsic component of plasma membrane)|interpro:IPR002205(DNA topoisomerase, type IIA, subunit A or C-terminal)|interpro:IPR005741(DNA topoisomerase IV, subunit A, Gram-positive)|interpro:IPR006691(DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel)|interpro:IPR013757(DNA topoisomerase, type IIA, subunit A, alpha-helical)|interpro:IPR013758(DNA topoisomerase, type IIA, subunit A or C-terminal, alpha-beta)|interpro:IPR013760(DNA topoisomerase, type IIA, central)|interpro:IPR035516|rcsb pdb:2NOV|rcsb pdb:3FOE|rcsb pdb:3FOF|rcsb pdb:3K9F|rcsb pdb:3KSA|rcsb pdb:3KSB|rcsb pdb:3LTN|rcsb pdb:3RAD|rcsb pdb:3RAE|rcsb pdb:3RAF|rcsb pdb:4I3H|rcsb pdb:4JUO|rcsb pdb:4KOE|rcsb pdb:4KPE|rcsb pdb:4KPF|rcsb pdb:4Z3O|rcsb pdb:4Z4Q|rcsb pdb:4Z53	refseq:WP_000037283.1|dip:DIP-48520N|go:"GO:0046872"(metal ion binding)|go:"GO:0007059"(chromosome segregation)|interpro:IPR001241(DNA topoisomerase, type IIA, subunit B or N-terminal)|interpro:IPR002288(DNA topoisomerase, type IIA, subunit B, C-terminal)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR005740(DNA topoisomerase IV, subunit B, Gram-positive)|interpro:IPR006171(TOPRIM)|interpro:IPR013506(DNA topoisomerase, type IIA, subunit B, region 2)|interpro:IPR013759(DNA topoisomerase, type IIA, subunit B or N-terminal, alpha-beta)|interpro:IPR013760(DNA topoisomerase, type IIA, central)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR018522|interpro:IPR020568|interpro:IPR036890|rcsb pdb:3FOE|rcsb pdb:3FOF|rcsb pdb:3K9F|rcsb pdb:3KSA|rcsb pdb:3KSB|rcsb pdb:3LTN|rcsb pdb:3RAD|rcsb pdb:3RAE|rcsb pdb:3RAF|rcsb pdb:4I3H|rcsb pdb:4JUO|rcsb pdb:4KOE|rcsb pdb:4KPE|rcsb pdb:4KPF|rcsb pdb:4Z3O|rcsb pdb:4Z4Q|rcsb pdb:4Z53|rcsb pdb:5J5P|rcsb pdb:5J5Q|ensemblbacteria:AAK74981(transcript)|ensemblbacteria:SP_0852(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003918"("DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005694"(chromosome)|go:"GO:0006265"(DNA topological change)	psi-mi:"MI:0465"(dip)	crc64:D4D17BD5DED63C05	crc64:B688A526C9A4E7BA	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/06	2017/08/10	rogid:rQi2xGaPSq2UwEYXIDoxgvvg01c170187	rogid:FfkBkzSJ28YZyD0xKiVSIEU1J/M170187	rigid:h1Am7kUelzNrjz2/zvNO+mR4lhs	false	binding-associated region:1-488	binding-associated region:404-647	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)