#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P02730	uniprotkb:P02724	intact:EBI-7576138|uniprotkb:Q9UDJ1|uniprotkb:Q1ZZ45|uniprotkb:G4V2I6|uniprotkb:Q4VB84|uniprotkb:Q4KKW9|uniprotkb:P78487|intact:MINT-1344291|uniprotkb:Q9UCY7|ensembl:ENSP00000262418	intact:EBI-702665|uniprotkb:Q9BS51|uniprotkb:A8K3E6|uniprotkb:B8Q182|uniprotkb:B8Q185	psi-mi:b3at_human(display_long)|uniprotkb:SLC4A1(gene name)|psi-mi:SLC4A1(display_short)|uniprotkb:AE1(gene name synonym)|uniprotkb:DI(gene name synonym)|uniprotkb:EPB3(gene name synonym)|uniprotkb:Anion exchange protein 1(gene name synonym)|uniprotkb:Solute carrier family 4 member 1(gene name synonym)	psi-mi:glpa_human(display_long)|uniprotkb:PAS-2(gene name synonym)|uniprotkb:Sialoglycoprotein alpha(gene name synonym)|uniprotkb:MN sialoglycoprotein(gene name synonym)|uniprotkb:GYPA(gene name)|psi-mi:GYPA(display_short)|uniprotkb:GPA(gene name synonym)	psi-mi:"MI:0663"(confocal microscopy)	Pang et al. (2009)	pubmed:19438409|imex:IM-25823	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-15486401|imex:IM-25823-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000333.1|refseq:XP_005257650.1|ensembl:ENSG00000004939(gene)|ensembl:ENST00000262418(transcript)|go:"GO:0007596"(blood coagulation)|go:"GO:0005452"(inorganic anion exchanger activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006820"(anion transport)|go:"GO:0006821"(chloride transport)|go:"GO:0006873"(cellular ion homeostasis)|go:"GO:0008509"(anion transmembrane transporter activity)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0015106"(bicarbonate transmembrane transporter activity)|go:"GO:0015108"(chloride transmembrane transporter activity)|go:"GO:0015301"("anion:anion antiporter activity")|go:"GO:0015701"(bicarbonate transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0017121"(plasma membrane phospholipid scrambling)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0030018"(Z disc)|go:"GO:0030492"(hemoglobin binding)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0035811"(negative regulation of urine volume)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0045852"(pH elevation)|go:"GO:0048821"(erythrocyte development)|go:"GO:0050801"(ion homeostasis)|go:"GO:0051354"(negative regulation of oxidoreductase activity)|go:"GO:0051453"(regulation of intracellular pH)|go:"GO:0055085"(transmembrane transport)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:1904539"(negative regulation of glycolytic process through fructose-6-phosphate)|interpro:IPR001717(Anion exchange protein)|interpro:IPR002977(Anion exchange protein 1)|interpro:IPR003020(Bicarbonate transporter, eukaryotic)|interpro:IPR011531(Bicarbonate transporter, C-terminal)|interpro:IPR013769(Bicarbonate transporter, cytoplasmic)|interpro:IPR016152(Phosphotransferase/anion transporter)|interpro:IPR018241|mint:P02730|rcsb pdb:1BH7|rcsb pdb:1BNX|rcsb pdb:1BTQ|rcsb pdb:1BTR|rcsb pdb:1BTS|rcsb pdb:1BTT|rcsb pdb:1BZK|rcsb pdb:1HYN|rcsb pdb:2BTA|rcsb pdb:2BTB|rcsb pdb:3BTB|rcsb pdb:4KY9|rcsb pdb:4YZF|reactome:R-HSA-1237044|reactome:R-HSA-1247673|reactome:R-HSA-425381|reactome:R-HSA-5619050|dip:DIP-42428N	refseq:NP_002090.4|interpro:IPR001195(Glycophorin A and B)|interpro:IPR018938|rcsb pdb:1AFO|rcsb pdb:1MSR|rcsb pdb:2KPE|rcsb pdb:2KPF|rcsb pdb:5EH4|rcsb pdb:5EH6|refseq:NP_001295119.1|refseq:XP_016863624.1|reactome:R-HSA-202733|go:"GO:0001618"(virus receptor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0042802"(identical protein binding)	go:"GO:0009986"(cell surface)|go:"GO:0005622"(intracellular anatomical structure)	function:"Defects in SLC4A1 are the cause of elliptocytosis type 4 (EL4) [MIM:109270]. EL4 is a Rhesus-unlinked form of hereditary elliptocytosis, a genetically heterogeneous, autosomal dominant hematologic disorder. It is characterized by variable hemolytic anemia and elliptical or oval red cell shape"|function:"Defects in SLC4A1 are the cause of autosomal dominant distal renal tubular acidosis (dRTA) [MIM:179800]. This disease is characterized by reduced ability to acidify urine, variable hyperchloremic hypokalemic metabolic acidosis, nephrocalcinosis, and nephrolithiasis"|function:"Defects in SLC4A1 are the cause of autosomal recessive distal renal tubular acidosis (dRTA) [MIM:611590]"|function:"Band 3 is the major integral glycoprotein of the erythrocyte membrane. Band 3 has two functional domains. Its integral domain mediates a 1:1 exchange of inorganic anions across the membrane, whereas its cytoplasmic domain provides binding sites for cytoskeletal proteins, glycolytic enzymes, and hemoglobin"|comment:mint|function:"Defects in SLC4A1 are a cause of hereditary spherocytosis (HS) [MIM:109270]. HS is a hematologic disorder leading to chronic hemolytic anemia and characterized by numerous abnormally shaped erythrocytes which are generally spheroidal"	-	figure legend:Figure 5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-k_562)|taxid:9606(Homo sapiens myeloid leukemia cells.)	-	2017/06/05	2017/08/18	rogid:rmDsGx5dB4bRCaXClZk+AptTR6M9606	rogid:QYkwVSmE7sIqAeoopqJRWvEu1PI9606	rigid:mZu1HiKujEEPG8oSJaihVZLVYz4	false	ha tag:557-557	-	-	-	psi-mi:"MI:1200"(immunocytochemistry)	psi-mi:"MI:1200"(immunocytochemistry)
uniprotkb:P02730	uniprotkb:P02724	intact:EBI-7576138|uniprotkb:Q9UDJ1|uniprotkb:Q1ZZ45|uniprotkb:G4V2I6|uniprotkb:Q4VB84|uniprotkb:Q4KKW9|uniprotkb:P78487|intact:MINT-1344291|uniprotkb:Q9UCY7|ensembl:ENSP00000262418	intact:EBI-702665|uniprotkb:Q9BS51|uniprotkb:A8K3E6|uniprotkb:B8Q182|uniprotkb:B8Q185	psi-mi:b3at_human(display_long)|uniprotkb:SLC4A1(gene name)|psi-mi:SLC4A1(display_short)|uniprotkb:AE1(gene name synonym)|uniprotkb:DI(gene name synonym)|uniprotkb:EPB3(gene name synonym)|uniprotkb:Anion exchange protein 1(gene name synonym)|uniprotkb:Solute carrier family 4 member 1(gene name synonym)	psi-mi:glpa_human(display_long)|uniprotkb:PAS-2(gene name synonym)|uniprotkb:Sialoglycoprotein alpha(gene name synonym)|uniprotkb:MN sialoglycoprotein(gene name synonym)|uniprotkb:GYPA(gene name)|psi-mi:GYPA(display_short)|uniprotkb:GPA(gene name synonym)	psi-mi:"MI:0663"(confocal microscopy)	Pang et al. (2009)	pubmed:19438409|imex:IM-25823	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-15486443|imex:IM-25823-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000333.1|refseq:XP_005257650.1|ensembl:ENSG00000004939(gene)|ensembl:ENST00000262418(transcript)|go:"GO:0007596"(blood coagulation)|go:"GO:0005452"(inorganic anion exchanger activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006820"(anion transport)|go:"GO:0006821"(chloride transport)|go:"GO:0006873"(cellular ion homeostasis)|go:"GO:0008509"(anion transmembrane transporter activity)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0015106"(bicarbonate transmembrane transporter activity)|go:"GO:0015108"(chloride transmembrane transporter activity)|go:"GO:0015301"("anion:anion antiporter activity")|go:"GO:0015701"(bicarbonate transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0017121"(plasma membrane phospholipid scrambling)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0030018"(Z disc)|go:"GO:0030492"(hemoglobin binding)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0035811"(negative regulation of urine volume)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0045852"(pH elevation)|go:"GO:0048821"(erythrocyte development)|go:"GO:0050801"(ion homeostasis)|go:"GO:0051354"(negative regulation of oxidoreductase activity)|go:"GO:0051453"(regulation of intracellular pH)|go:"GO:0055085"(transmembrane transport)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:1904539"(negative regulation of glycolytic process through fructose-6-phosphate)|interpro:IPR001717(Anion exchange protein)|interpro:IPR002977(Anion exchange protein 1)|interpro:IPR003020(Bicarbonate transporter, eukaryotic)|interpro:IPR011531(Bicarbonate transporter, C-terminal)|interpro:IPR013769(Bicarbonate transporter, cytoplasmic)|interpro:IPR016152(Phosphotransferase/anion transporter)|interpro:IPR018241|mint:P02730|rcsb pdb:1BH7|rcsb pdb:1BNX|rcsb pdb:1BTQ|rcsb pdb:1BTR|rcsb pdb:1BTS|rcsb pdb:1BTT|rcsb pdb:1BZK|rcsb pdb:1HYN|rcsb pdb:2BTA|rcsb pdb:2BTB|rcsb pdb:3BTB|rcsb pdb:4KY9|rcsb pdb:4YZF|reactome:R-HSA-1237044|reactome:R-HSA-1247673|reactome:R-HSA-425381|reactome:R-HSA-5619050|dip:DIP-42428N	refseq:NP_002090.4|interpro:IPR001195(Glycophorin A and B)|interpro:IPR018938|rcsb pdb:1AFO|rcsb pdb:1MSR|rcsb pdb:2KPE|rcsb pdb:2KPF|rcsb pdb:5EH4|rcsb pdb:5EH6|refseq:NP_001295119.1|refseq:XP_016863624.1|reactome:R-HSA-202733|go:"GO:0001618"(virus receptor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0042802"(identical protein binding)	go:"GO:0005783"(endoplasmic reticulum)	function:"Defects in SLC4A1 are the cause of elliptocytosis type 4 (EL4) [MIM:109270]. EL4 is a Rhesus-unlinked form of hereditary elliptocytosis, a genetically heterogeneous, autosomal dominant hematologic disorder. It is characterized by variable hemolytic anemia and elliptical or oval red cell shape"|function:"Defects in SLC4A1 are the cause of autosomal dominant distal renal tubular acidosis (dRTA) [MIM:179800]. This disease is characterized by reduced ability to acidify urine, variable hyperchloremic hypokalemic metabolic acidosis, nephrocalcinosis, and nephrolithiasis"|function:"Defects in SLC4A1 are the cause of autosomal recessive distal renal tubular acidosis (dRTA) [MIM:611590]"|function:"Band 3 is the major integral glycoprotein of the erythrocyte membrane. Band 3 has two functional domains. Its integral domain mediates a 1:1 exchange of inorganic anions across the membrane, whereas its cytoplasmic domain provides binding sites for cytoskeletal proteins, glycolytic enzymes, and hemoglobin"|comment:mint|function:"Defects in SLC4A1 are a cause of hereditary spherocytosis (HS) [MIM:109270]. HS is a hematologic disorder leading to chronic hemolytic anemia and characterized by numerous abnormally shaped erythrocytes which are generally spheroidal"	-	figure legend:Figure 8A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-k_562)|taxid:9606(Homo sapiens myeloid leukemia cells.)	-	2017/06/05	2017/07/27	rogid:rmDsGx5dB4bRCaXClZk+AptTR6M9606	rogid:QYkwVSmE7sIqAeoopqJRWvEu1PI9606	rigid:mZu1HiKujEEPG8oSJaihVZLVYz4	false	ha tag:557-557|mutation:760-760	-	-	-	psi-mi:"MI:1200"(immunocytochemistry)	psi-mi:"MI:1200"(immunocytochemistry)
uniprotkb:P02730	uniprotkb:P02724	intact:EBI-7576138|uniprotkb:Q9UDJ1|uniprotkb:Q1ZZ45|uniprotkb:G4V2I6|uniprotkb:Q4VB84|uniprotkb:Q4KKW9|uniprotkb:P78487|intact:MINT-1344291|uniprotkb:Q9UCY7|ensembl:ENSP00000262418	intact:EBI-702665|uniprotkb:Q9BS51|uniprotkb:A8K3E6|uniprotkb:B8Q182|uniprotkb:B8Q185	psi-mi:b3at_human(display_long)|uniprotkb:SLC4A1(gene name)|psi-mi:SLC4A1(display_short)|uniprotkb:AE1(gene name synonym)|uniprotkb:DI(gene name synonym)|uniprotkb:EPB3(gene name synonym)|uniprotkb:Anion exchange protein 1(gene name synonym)|uniprotkb:Solute carrier family 4 member 1(gene name synonym)	psi-mi:glpa_human(display_long)|uniprotkb:PAS-2(gene name synonym)|uniprotkb:Sialoglycoprotein alpha(gene name synonym)|uniprotkb:MN sialoglycoprotein(gene name synonym)|uniprotkb:GYPA(gene name)|psi-mi:GYPA(display_short)|uniprotkb:GPA(gene name synonym)	psi-mi:"MI:0054"(fluorescence-activated cell sorting)	Pang et al. (2009)	pubmed:19438409|imex:IM-25823	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-15486416|imex:IM-25823-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000333.1|refseq:XP_005257650.1|ensembl:ENSG00000004939(gene)|ensembl:ENST00000262418(transcript)|go:"GO:0007596"(blood coagulation)|go:"GO:0005452"(inorganic anion exchanger activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006820"(anion transport)|go:"GO:0006821"(chloride transport)|go:"GO:0006873"(cellular ion homeostasis)|go:"GO:0008509"(anion transmembrane transporter activity)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0015106"(bicarbonate transmembrane transporter activity)|go:"GO:0015108"(chloride transmembrane transporter activity)|go:"GO:0015301"("anion:anion antiporter activity")|go:"GO:0015701"(bicarbonate transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0017121"(plasma membrane phospholipid scrambling)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0030018"(Z disc)|go:"GO:0030492"(hemoglobin binding)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0035811"(negative regulation of urine volume)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0045852"(pH elevation)|go:"GO:0048821"(erythrocyte development)|go:"GO:0050801"(ion homeostasis)|go:"GO:0051354"(negative regulation of oxidoreductase activity)|go:"GO:0051453"(regulation of intracellular pH)|go:"GO:0055085"(transmembrane transport)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:1904539"(negative regulation of glycolytic process through fructose-6-phosphate)|interpro:IPR001717(Anion exchange protein)|interpro:IPR002977(Anion exchange protein 1)|interpro:IPR003020(Bicarbonate transporter, eukaryotic)|interpro:IPR011531(Bicarbonate transporter, C-terminal)|interpro:IPR013769(Bicarbonate transporter, cytoplasmic)|interpro:IPR016152(Phosphotransferase/anion transporter)|interpro:IPR018241|mint:P02730|rcsb pdb:1BH7|rcsb pdb:1BNX|rcsb pdb:1BTQ|rcsb pdb:1BTR|rcsb pdb:1BTS|rcsb pdb:1BTT|rcsb pdb:1BZK|rcsb pdb:1HYN|rcsb pdb:2BTA|rcsb pdb:2BTB|rcsb pdb:3BTB|rcsb pdb:4KY9|rcsb pdb:4YZF|reactome:R-HSA-1237044|reactome:R-HSA-1247673|reactome:R-HSA-425381|reactome:R-HSA-5619050|dip:DIP-42428N	refseq:NP_002090.4|interpro:IPR001195(Glycophorin A and B)|interpro:IPR018938|rcsb pdb:1AFO|rcsb pdb:1MSR|rcsb pdb:2KPE|rcsb pdb:2KPF|rcsb pdb:5EH4|rcsb pdb:5EH6|refseq:NP_001295119.1|refseq:XP_016863624.1|reactome:R-HSA-202733|go:"GO:0001618"(virus receptor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0042802"(identical protein binding)	go:"GO:0009986"(cell surface)	function:"Defects in SLC4A1 are the cause of elliptocytosis type 4 (EL4) [MIM:109270]. EL4 is a Rhesus-unlinked form of hereditary elliptocytosis, a genetically heterogeneous, autosomal dominant hematologic disorder. It is characterized by variable hemolytic anemia and elliptical or oval red cell shape"|function:"Defects in SLC4A1 are the cause of autosomal dominant distal renal tubular acidosis (dRTA) [MIM:179800]. This disease is characterized by reduced ability to acidify urine, variable hyperchloremic hypokalemic metabolic acidosis, nephrocalcinosis, and nephrolithiasis"|function:"Defects in SLC4A1 are the cause of autosomal recessive distal renal tubular acidosis (dRTA) [MIM:611590]"|function:"Band 3 is the major integral glycoprotein of the erythrocyte membrane. Band 3 has two functional domains. Its integral domain mediates a 1:1 exchange of inorganic anions across the membrane, whereas its cytoplasmic domain provides binding sites for cytoskeletal proteins, glycolytic enzymes, and hemoglobin"|comment:mint|function:"Defects in SLC4A1 are a cause of hereditary spherocytosis (HS) [MIM:109270]. HS is a hematologic disorder leading to chronic hemolytic anemia and characterized by numerous abnormally shaped erythrocytes which are generally spheroidal"	-	figure legend:Figure 6A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/06/05	2017/07/26	rogid:rmDsGx5dB4bRCaXClZk+AptTR6M9606	rogid:QYkwVSmE7sIqAeoopqJRWvEu1PI9606	rigid:mZu1HiKujEEPG8oSJaihVZLVYz4	false	ha tag:557-557	-	-	-	psi-mi:"MI:0421"(identification by antibody)	psi-mi:"MI:0421"(identification by antibody)
uniprotkb:P02730	uniprotkb:P02724	intact:EBI-7576138|uniprotkb:Q9UDJ1|uniprotkb:Q1ZZ45|uniprotkb:G4V2I6|uniprotkb:Q4VB84|uniprotkb:Q4KKW9|uniprotkb:P78487|intact:MINT-1344291|uniprotkb:Q9UCY7|ensembl:ENSP00000262418	intact:EBI-702665|uniprotkb:Q9BS51|uniprotkb:A8K3E6|uniprotkb:B8Q182|uniprotkb:B8Q185	psi-mi:b3at_human(display_long)|uniprotkb:SLC4A1(gene name)|psi-mi:SLC4A1(display_short)|uniprotkb:AE1(gene name synonym)|uniprotkb:DI(gene name synonym)|uniprotkb:EPB3(gene name synonym)|uniprotkb:Anion exchange protein 1(gene name synonym)|uniprotkb:Solute carrier family 4 member 1(gene name synonym)	psi-mi:glpa_human(display_long)|uniprotkb:PAS-2(gene name synonym)|uniprotkb:Sialoglycoprotein alpha(gene name synonym)|uniprotkb:MN sialoglycoprotein(gene name synonym)|uniprotkb:GYPA(gene name)|psi-mi:GYPA(display_short)|uniprotkb:GPA(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Pang et al. (2009)	pubmed:19438409|imex:IM-25823	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-15486435|imex:IM-25823-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000333.1|refseq:XP_005257650.1|ensembl:ENSG00000004939(gene)|ensembl:ENST00000262418(transcript)|go:"GO:0007596"(blood coagulation)|go:"GO:0005452"(inorganic anion exchanger activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006820"(anion transport)|go:"GO:0006821"(chloride transport)|go:"GO:0006873"(cellular ion homeostasis)|go:"GO:0008509"(anion transmembrane transporter activity)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0015106"(bicarbonate transmembrane transporter activity)|go:"GO:0015108"(chloride transmembrane transporter activity)|go:"GO:0015301"("anion:anion antiporter activity")|go:"GO:0015701"(bicarbonate transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0017121"(plasma membrane phospholipid scrambling)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0030018"(Z disc)|go:"GO:0030492"(hemoglobin binding)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0035811"(negative regulation of urine volume)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0045852"(pH elevation)|go:"GO:0048821"(erythrocyte development)|go:"GO:0050801"(ion homeostasis)|go:"GO:0051354"(negative regulation of oxidoreductase activity)|go:"GO:0051453"(regulation of intracellular pH)|go:"GO:0055085"(transmembrane transport)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:1904539"(negative regulation of glycolytic process through fructose-6-phosphate)|interpro:IPR001717(Anion exchange protein)|interpro:IPR002977(Anion exchange protein 1)|interpro:IPR003020(Bicarbonate transporter, eukaryotic)|interpro:IPR011531(Bicarbonate transporter, C-terminal)|interpro:IPR013769(Bicarbonate transporter, cytoplasmic)|interpro:IPR016152(Phosphotransferase/anion transporter)|interpro:IPR018241|mint:P02730|rcsb pdb:1BH7|rcsb pdb:1BNX|rcsb pdb:1BTQ|rcsb pdb:1BTR|rcsb pdb:1BTS|rcsb pdb:1BTT|rcsb pdb:1BZK|rcsb pdb:1HYN|rcsb pdb:2BTA|rcsb pdb:2BTB|rcsb pdb:3BTB|rcsb pdb:4KY9|rcsb pdb:4YZF|reactome:R-HSA-1237044|reactome:R-HSA-1247673|reactome:R-HSA-425381|reactome:R-HSA-5619050|dip:DIP-42428N	refseq:NP_002090.4|interpro:IPR001195(Glycophorin A and B)|interpro:IPR018938|rcsb pdb:1AFO|rcsb pdb:1MSR|rcsb pdb:2KPE|rcsb pdb:2KPF|rcsb pdb:5EH4|rcsb pdb:5EH6|refseq:NP_001295119.1|refseq:XP_016863624.1|reactome:R-HSA-202733|go:"GO:0001618"(virus receptor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0042802"(identical protein binding)	go:"GO:0009986"(cell surface)	function:"Defects in SLC4A1 are the cause of elliptocytosis type 4 (EL4) [MIM:109270]. EL4 is a Rhesus-unlinked form of hereditary elliptocytosis, a genetically heterogeneous, autosomal dominant hematologic disorder. It is characterized by variable hemolytic anemia and elliptical or oval red cell shape"|function:"Defects in SLC4A1 are the cause of autosomal dominant distal renal tubular acidosis (dRTA) [MIM:179800]. This disease is characterized by reduced ability to acidify urine, variable hyperchloremic hypokalemic metabolic acidosis, nephrocalcinosis, and nephrolithiasis"|function:"Defects in SLC4A1 are the cause of autosomal recessive distal renal tubular acidosis (dRTA) [MIM:611590]"|function:"Band 3 is the major integral glycoprotein of the erythrocyte membrane. Band 3 has two functional domains. Its integral domain mediates a 1:1 exchange of inorganic anions across the membrane, whereas its cytoplasmic domain provides binding sites for cytoskeletal proteins, glycolytic enzymes, and hemoglobin"|comment:mint|function:"Defects in SLC4A1 are a cause of hereditary spherocytosis (HS) [MIM:109270]. HS is a hematologic disorder leading to chronic hemolytic anemia and characterized by numerous abnormally shaped erythrocytes which are generally spheroidal"	-	figure legend:Figure 7A, 8B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-k_562)|taxid:9606(Homo sapiens myeloid leukemia cells.)	-	2017/06/05	2017/07/26	rogid:rmDsGx5dB4bRCaXClZk+AptTR6M9606	rogid:QYkwVSmE7sIqAeoopqJRWvEu1PI9606	rigid:mZu1HiKujEEPG8oSJaihVZLVYz4	false	ha tag:557-557|mutation with no effect:760-760	-	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)