#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q8TD07 uniprotkb:P26718 intact:EBI-16365677|ensembl:ENSP00000349709|uniprotkb:A6YF59|uniprotkb:Q5VYB7|uniprotkb:Q5VYB8|uniprotkb:Q8TEZ2|uniprotkb:Q96L41|intact:EBI-16417333|intact:EBI-16417358 intact:EBI-458344|ensembl:ENSP00000240618|ensembl:ENSP00000446003|uniprotkb:Q9NR41|uniprotkb:A8K7K5|uniprotkb:A8K7P4 psi-mi:rae1e_human(display_long)|uniprotkb:NKG2D ligand 4(gene name synonym)|uniprotkb:Lymphocyte effector toxicity activation ligand(gene name synonym)|uniprotkb:RAE-1-like transcript 4(gene name synonym)|uniprotkb:UL16-binding protein 4(gene name synonym)|uniprotkb:RAET1E(gene name)|psi-mi:RAET1E(display_short)|uniprotkb:LETAL(gene name synonym)|uniprotkb:N2DL4(gene name synonym)|uniprotkb:ULBP4(gene name synonym)|uniprotkb:UNQ1867/PRO4303(orf name) psi-mi:nkg2d_human(display_long)|uniprotkb:KLRK1(gene name)|psi-mi:KLRK1(display_short)|uniprotkb:NKG2D(gene name synonym)|uniprotkb:NKG2-D-activating NK receptor(gene name synonym)|uniprotkb:NK cell receptor D(gene name synonym)|uniprotkb:Killer cell lectin-like receptor subfamily K member 1(gene name synonym)|uniprotkb:D12S2489E(gene name synonym) psi-mi:"MI:0054"(fluorescence-activated cell sorting) Kong et al. (2009) pubmed:19436053|imex:IM-26147 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16417485|imex:IM-26147-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000164520(gene)|ensembl:ENST00000357183(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0045954"(positive regulation of natural killer cell mediated cytotoxicity)|go:"GO:0046703"(natural killer cell lectin-like receptor binding)|interpro:IPR011161(MHC class I-like antigen recognition)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR037055|reactome:R-HSA-198933|refseq:NP_001230254.1|refseq:NP_001230256.1|refseq:NP_001230257.1|refseq:NP_631904.1|refseq:XP_011533781.1 reactome:R-HSA-2424491|reactome:R-HSA-2172127|ensembl:ENSG00000213809(gene)|ensembl:ENST00000540818(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030101"(natural killer cell activation)|go:"GO:0030154"(cell differentiation)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0031295"(T cell costimulation)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0045954"(positive regulation of natural killer cell mediated cytotoxicity)|go:"GO:2000502"(negative regulation of natural killer cell chemotaxis)|interpro:IPR001304(C-type lectin)|interpro:IPR016186(C-type lectin-like)|interpro:IPR016187(C-type lectin fold)|interpro:IPR033992|interpro:IPR042169|rcsb pdb:1HYR|rcsb pdb:1KCG|rcsb pdb:1MPU|rcsb pdb:4PDC|rcsb pdb:4S0U|ensembl:ENST00000240618(transcript)|reactome:R-HSA-198933|refseq:NP_001186734.1|refseq:NP_031386.2|dip:DIP-31100N - - - figure legend:3A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/07/05 2017/09/19 rogid:ED1vlb7qfcUNlxg90bEKKbME8TA9606 rogid:KAqdqIVvc4LUwx7y0KRMc87FsUM9606 rigid:kGXIKFHd7xLL7QjTQ6QL1mX29wQ false sufficient binding region:1-226|his tag:c-c fc-igg tag:n-n|sufficient binding region:78-216 - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody)