#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P77335 uniprotkb:P77335 intact:EBI-8516553|uniprotkb:Q47276|intact:MINT-2737936|uniprotkb:Q9R3G4|uniprotkb:Q8VU70|ensemblbacteria:AAC74266|ensemblbacteria:BAA36016 intact:EBI-8516553|uniprotkb:Q47276|intact:MINT-2737936|uniprotkb:Q9R3G4|uniprotkb:Q8VU70|ensemblbacteria:AAC74266|ensemblbacteria:BAA36016 psi-mi:hlye_ecoli(display_long)|uniprotkb:hlyE(gene name)|psi-mi:hlyE(display_short)|uniprotkb:clyA(gene name synonym)|uniprotkb:hpr(gene name synonym)|uniprotkb:sheA(gene name synonym)|uniprotkb:Cytotoxin ClyA(gene name synonym)|uniprotkb:Hemolysis-inducing protein(gene name synonym)|uniprotkb:Latent pore-forming 34 kDa hemolysin(gene name synonym)|uniprotkb:Silent hemolysin SheA(gene name synonym)|uniprotkb:ycgD(gene name synonym)|uniprotkb:JW5181(locus name)|uniprotkb:b1182(locus name) psi-mi:hlye_ecoli(display_long)|uniprotkb:hlyE(gene name)|psi-mi:hlyE(display_short)|uniprotkb:clyA(gene name synonym)|uniprotkb:hpr(gene name synonym)|uniprotkb:sheA(gene name synonym)|uniprotkb:Cytotoxin ClyA(gene name synonym)|uniprotkb:Hemolysis-inducing protein(gene name synonym)|uniprotkb:Latent pore-forming 34 kDa hemolysin(gene name synonym)|uniprotkb:Silent hemolysin SheA(gene name synonym)|uniprotkb:ycgD(gene name synonym)|uniprotkb:JW5181(locus name)|uniprotkb:b1182(locus name) psi-mi:"MI:0114"(x-ray crystallography) Mueller et al. (2009) pubmed:19421192|doi:10.1038/nature08026|imex:IM-17840 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15779339|imex:IM-17840-1|dip:DIP-74300E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_001336523.1|refseq:NP_415700.4|dip:DIP-9915N|mint:P77335|ensemblbacteria:AAC74266(transcript)|ensemblbacteria:b1182(gene)|ensemblbacteria:BAA36016(gene)|ensemblbacteria:BAA36016(transcript)|go:"GO:0001897"(cytolysis by symbiont of host cells)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0042597"(periplasmic space)|go:"GO:0042802"(identical protein binding)|go:"GO:0044179"(hemolysis in another organism)|go:"GO:0044532"(modulation of apoptotic process in another organism)|go:"GO:0090729"(toxin activity)|interpro:IPR027018|rcsb pdb:1QOY|rcsb pdb:2WCD|rcsb pdb:4PHO|rcsb pdb:4PHQ|rcsb pdb:6MRT|rcsb pdb:6MRU|rcsb pdb:6MRW refseq:WP_001336523.1|refseq:NP_415700.4|dip:DIP-9915N|mint:P77335|ensemblbacteria:AAC74266(transcript)|ensemblbacteria:b1182(gene)|ensemblbacteria:BAA36016(gene)|ensemblbacteria:BAA36016(transcript)|go:"GO:0001897"(cytolysis by symbiont of host cells)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0042597"(periplasmic space)|go:"GO:0042802"(identical protein binding)|go:"GO:0044179"(hemolysis in another organism)|go:"GO:0044532"(modulation of apoptotic process in another organism)|go:"GO:0090729"(toxin activity)|interpro:IPR027018|rcsb pdb:1QOY|rcsb pdb:2WCD|rcsb pdb:4PHO|rcsb pdb:4PHQ|rcsb pdb:6MRT|rcsb pdb:6MRU|rcsb pdb:6MRW psi-mi:"MI:0465"(dip) comment:mint comment:mint full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/06 2017/08/10 rogid:lXZ5RxhvQ1u8Tlapr6RJU0/Ct/c83333 rogid:lXZ5RxhvQ1u8Tlapr6RJU0/Ct/c83333 rigid:2fLUPdfaEvzteRTuLvQu+TLqoKI false - - - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P77335 uniprotkb:P77335 intact:EBI-8516553|uniprotkb:Q47276|intact:MINT-2737936|uniprotkb:Q9R3G4|uniprotkb:Q8VU70|ensemblbacteria:AAC74266|ensemblbacteria:BAA36016 intact:EBI-8516553|uniprotkb:Q47276|intact:MINT-2737936|uniprotkb:Q9R3G4|uniprotkb:Q8VU70|ensemblbacteria:AAC74266|ensemblbacteria:BAA36016 psi-mi:hlye_ecoli(display_long)|uniprotkb:hlyE(gene name)|psi-mi:hlyE(display_short)|uniprotkb:clyA(gene name synonym)|uniprotkb:hpr(gene name synonym)|uniprotkb:sheA(gene name synonym)|uniprotkb:Cytotoxin ClyA(gene name synonym)|uniprotkb:Hemolysis-inducing protein(gene name synonym)|uniprotkb:Latent pore-forming 34 kDa hemolysin(gene name synonym)|uniprotkb:Silent hemolysin SheA(gene name synonym)|uniprotkb:ycgD(gene name synonym)|uniprotkb:JW5181(locus name)|uniprotkb:b1182(locus name) psi-mi:hlye_ecoli(display_long)|uniprotkb:hlyE(gene name)|psi-mi:hlyE(display_short)|uniprotkb:clyA(gene name synonym)|uniprotkb:hpr(gene name synonym)|uniprotkb:sheA(gene name synonym)|uniprotkb:Cytotoxin ClyA(gene name synonym)|uniprotkb:Hemolysis-inducing protein(gene name synonym)|uniprotkb:Latent pore-forming 34 kDa hemolysin(gene name synonym)|uniprotkb:Silent hemolysin SheA(gene name synonym)|uniprotkb:ycgD(gene name synonym)|uniprotkb:JW5181(locus name)|uniprotkb:b1182(locus name) psi-mi:"MI:0928"(filter trap assay) Mueller et al. (2009) pubmed:19421192|doi:10.1038/nature08026|imex:IM-17840 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15779355|imex:IM-17840-2|dip:DIP-74300E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_001336523.1|refseq:NP_415700.4|dip:DIP-9915N|mint:P77335|ensemblbacteria:AAC74266(transcript)|ensemblbacteria:b1182(gene)|ensemblbacteria:BAA36016(gene)|ensemblbacteria:BAA36016(transcript)|go:"GO:0001897"(cytolysis by symbiont of host cells)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0042597"(periplasmic space)|go:"GO:0042802"(identical protein binding)|go:"GO:0044179"(hemolysis in another organism)|go:"GO:0044532"(modulation of apoptotic process in another organism)|go:"GO:0090729"(toxin activity)|interpro:IPR027018|rcsb pdb:1QOY|rcsb pdb:2WCD|rcsb pdb:4PHO|rcsb pdb:4PHQ|rcsb pdb:6MRT|rcsb pdb:6MRU|rcsb pdb:6MRW refseq:WP_001336523.1|refseq:NP_415700.4|dip:DIP-9915N|mint:P77335|ensemblbacteria:AAC74266(transcript)|ensemblbacteria:b1182(gene)|ensemblbacteria:BAA36016(gene)|ensemblbacteria:BAA36016(transcript)|go:"GO:0001897"(cytolysis by symbiont of host cells)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0042597"(periplasmic space)|go:"GO:0042802"(identical protein binding)|go:"GO:0044179"(hemolysis in another organism)|go:"GO:0044532"(modulation of apoptotic process in another organism)|go:"GO:0090729"(toxin activity)|interpro:IPR027018|rcsb pdb:1QOY|rcsb pdb:2WCD|rcsb pdb:4PHO|rcsb pdb:4PHQ|rcsb pdb:6MRT|rcsb pdb:6MRU|rcsb pdb:6MRW psi-mi:"MI:0465"(dip) comment:mint comment:mint full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/06 2017/08/10 rogid:lXZ5RxhvQ1u8Tlapr6RJU0/Ct/c83333 rogid:lXZ5RxhvQ1u8Tlapr6RJU0/Ct/c83333 rigid:2fLUPdfaEvzteRTuLvQu+TLqoKI false - - - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)