#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q9I9P4	uniprotkb:Q9I9P9	intact:EBI-15779251	intact:EBI-15779205|ensembl:ENSDARP00000044755|ensembl:ENSDARP00000111803|ensembl:ENSDARP00000145128|uniprotkb:Q4V964|uniprotkb:Q9PUN4	psi-mi:q9i9p4_danre(display_long)|uniprotkb:smad4a(gene name)|psi-mi:smad4a(display_short)|uniprotkb:madh4(gene name synonym)|uniprotkb:smad4(gene name synonym)	psi-mi:smad2_danre(display_long)|uniprotkb:smad2(gene name)|psi-mi:smad2(display_short)|uniprotkb:madh2(gene name synonym)|uniprotkb:SMAD family member 2(gene name synonym)	psi-mi:"MI:0809"(bimolecular fluorescence complementation)	Harvey et al. (2009)	pubmed:19419239|doi:10.1371/journal.pbio.1000101|imex:IM-14156	taxid:7955(danre)|taxid:7955("Danio rerio (Zebrafish)")	taxid:7955(danre)|taxid:7955("Danio rerio (Zebrafish)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15779272|imex:IM-14156-1|dip:DIP-102837E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0048264"(determination of ventral identity)|go:"GO:0048738"(cardiac muscle tissue development)|go:"GO:0060026"(convergent extension)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0070411"(I-SMAD binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071144"(heteromeric SMAD protein complex)|interpro:IPR001132(SMAD domain, Dwarfin-type)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR013790(Dwarfin)|interpro:IPR017855(SMAD domain-like)|dip:DIP-48410N	reactome:R-DRE-1181150|reactome:R-DRE-1502540|reactome:R-DRE-2173788|reactome:R-DRE-2173789|reactome:R-DRE-2173795|reactome:R-DRE-2173796|reactome:R-DRE-5689880|reactome:R-DRE-9617828|interpro:IPR036578|ensembl:ENSDARG00000006389(gene)|ensembl:ENSDART00000044756(transcript)|ensembl:ENSDART00000128579(transcript)|ensembl:ENSDART00000184617(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0021999"(neural plate anterior/posterior regionalization)|go:"GO:0030154"(cell differentiation)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0038092"(nodal signaling pathway)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0060282"(positive regulation of oocyte development)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0070411"(I-SMAD binding)|go:"GO:0071144"(heteromeric SMAD protein complex)|interpro:IPR001132(SMAD domain, Dwarfin-type)|interpro:IPR003619(MAD homology 1, Dwarfin-type)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR013019(MAD homology, MH1)|interpro:IPR013790(Dwarfin)|interpro:IPR017855(SMAD domain-like)|refseq:NP_001276944.1|refseq:NP_571441.3|dip:DIP-41211N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7955(danre)|taxid:7955("Danio rerio (Zebrafish)")	-	2017/08/06	2017/08/10	rogid:Ug9WtWlvi9XsOa82O8Ln4xAt3QU7955	rogid:UABpiSyEaDEjqOD5jsAUG3RfQyA7955	rigid:Nr0NQ0pSM+NoLu0TB/TtgoSCoeE	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)