#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q9NUV7	uniprotkb:Q8NFR3	intact:EBI-11614219|uniprotkb:A2A2I4|uniprotkb:B9EK64|uniprotkb:Q05DQ8|uniprotkb:Q5T1U4|uniprotkb:Q9H1L1|uniprotkb:Q9H1Z0|ensembl:ENSP00000381968	intact:EBI-15778024|ensembl:ENSP00000352097|ensembl:ENSP00000420115|ensembl:ENSP00000480827|uniprotkb:B2R5D3|uniprotkb:D3DNM8|uniprotkb:Q0P5S6	psi-mi:sptc3_human(display_long)|uniprotkb:SPTLC3(gene name)|psi-mi:SPTLC3(display_short)|uniprotkb:C20orf38(gene name synonym)|uniprotkb:SPTLC2L(gene name synonym)|uniprotkb:Long chain base biosynthesis protein 2b(gene name synonym)|uniprotkb:Long chain base biosynthesis protein 3(gene name synonym)|uniprotkb:Serine-palmitoyl-CoA transferase 3(gene name synonym)	psi-mi:sptsb_human(display_long)|uniprotkb:SPTSSB(gene name)|psi-mi:SPTSSB(display_short)|uniprotkb:ADMP(gene name synonym)|uniprotkb:C3orf57(gene name synonym)|uniprotkb:SSSPTB(gene name synonym)|uniprotkb:Protein ADMP(gene name synonym)|uniprotkb:Small subunit of serine palmitoyltransferase B(gene name synonym)	psi-mi:"MI:0096"(pull down)	Han et al. (2009)	pubmed:19416851|doi:10.1073/pnas.0811269106|imex:IM-22435	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15778074|imex:IM-22435-4|dip:DIP-196137E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060797.2|ensembl:ENSG00000172296(gene)|ensembl:ENST00000399002(transcript)|go:"GO:0004758"(serine C-palmitoyltransferase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017059"(serine C-palmitoyltransferase complex)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0046512"(sphingosine biosynthetic process)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:0046520"(sphingoid biosynthetic process)|interpro:IPR001917(Aminotransferase, class-II, pyridoxal-phosphate binding site)|interpro:IPR004839(Aminotransferase, class I and II)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|reactome:R-HSA-1660661|dip:DIP-60753N	ensembl:ENSG00000196542(gene)|ensembl:ENST00000359175(transcript)|ensembl:ENST00000497137(transcript)|ensembl:ENST00000620149(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017059"(serine C-palmitoyltransferase complex)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:1904220"(regulation of serine C-palmitoyltransferase activity)|interpro:IPR024512|reactome:R-HSA-1660661|refseq:NP_001035189.1|refseq:NP_001307608.1|dip:DIP-60755N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/08/06	2017/08/10	rogid:3BQyhvhH2iX+TrEl+qfLy7UlhG49606	rogid:NJFRQVpvKft7NA7ZnHGZdt1x8xY9606	rigid:5SaWmXX0GcvUgdOSnrZGVa2XHoQ	false	tandem tag:c-c	ha tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9NUV7	uniprotkb:O15269	intact:EBI-11614219|uniprotkb:A2A2I4|uniprotkb:B9EK64|uniprotkb:Q05DQ8|uniprotkb:Q5T1U4|uniprotkb:Q9H1L1|uniprotkb:Q9H1Z0|ensembl:ENSP00000381968	intact:EBI-1044323|uniprotkb:Q5VWB4|uniprotkb:A8K681|uniprotkb:Q96IX6|ensembl:ENSP00000262554	psi-mi:sptc3_human(display_long)|uniprotkb:SPTLC3(gene name)|psi-mi:SPTLC3(display_short)|uniprotkb:C20orf38(gene name synonym)|uniprotkb:SPTLC2L(gene name synonym)|uniprotkb:Long chain base biosynthesis protein 2b(gene name synonym)|uniprotkb:Long chain base biosynthesis protein 3(gene name synonym)|uniprotkb:Serine-palmitoyl-CoA transferase 3(gene name synonym)	psi-mi:sptc1_human(display_long)|uniprotkb:Serine-palmitoyl-CoA transferase 1(gene name synonym)|uniprotkb:Long chain base biosynthesis protein 1(gene name synonym)|uniprotkb:SPTLC1(gene name)|psi-mi:SPTLC1(display_short)|uniprotkb:LCB1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Han et al. (2009)	pubmed:19416851|doi:10.1073/pnas.0811269106|imex:IM-22435	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15778074|imex:IM-22435-4|dip:DIP-196137E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060797.2|ensembl:ENSG00000172296(gene)|ensembl:ENST00000399002(transcript)|go:"GO:0004758"(serine C-palmitoyltransferase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017059"(serine C-palmitoyltransferase complex)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0046512"(sphingosine biosynthetic process)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:0046520"(sphingoid biosynthetic process)|interpro:IPR001917(Aminotransferase, class-II, pyridoxal-phosphate binding site)|interpro:IPR004839(Aminotransferase, class I and II)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|reactome:R-HSA-1660661|dip:DIP-60753N	refseq:NP_006406.1|refseq:NP_847894.1|refseq:NP_001268232.1|ensembl:ENSG00000090054(gene)|ensembl:ENST00000262554(transcript)|go:"GO:0004758"(serine C-palmitoyltransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006665"(sphingolipid metabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017059"(serine C-palmitoyltransferase complex)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0035339"(SPOTS complex)|go:"GO:0046512"(sphingosine biosynthetic process)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:1904504"(positive regulation of lipophagy)|go:"GO:1904649"(regulation of fat cell apoptotic process)|interpro:IPR004839(Aminotransferase, class I and II)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|mint:O15269|rcsb pdb:6M4N|rcsb pdb:6M4O|rcsb pdb:7CQI|rcsb pdb:7CQK|rcsb pdb:7K0I|rcsb pdb:7K0J|rcsb pdb:7K0K|rcsb pdb:7K0L|rcsb pdb:7K0M|rcsb pdb:7K0N|rcsb pdb:7K0O|rcsb pdb:7K0P|rcsb pdb:7K0Q|reactome:R-HSA-1660661|dip:DIP-45626N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/08/06	2017/08/10	rogid:3BQyhvhH2iX+TrEl+qfLy7UlhG49606	rogid:M/O7lbdRcUwB+r1wpHj2EtSD+kI9606	rigid:5SaWmXX0GcvUgdOSnrZGVa2XHoQ	false	tandem tag:c-c	ha tag:c-c	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q8NFR3	uniprotkb:Q9NUV7	intact:EBI-15778024|ensembl:ENSP00000352097|ensembl:ENSP00000420115|ensembl:ENSP00000480827|uniprotkb:B2R5D3|uniprotkb:D3DNM8|uniprotkb:Q0P5S6	intact:EBI-11614219|uniprotkb:A2A2I4|uniprotkb:B9EK64|uniprotkb:Q05DQ8|uniprotkb:Q5T1U4|uniprotkb:Q9H1L1|uniprotkb:Q9H1Z0|ensembl:ENSP00000381968	psi-mi:sptsb_human(display_long)|uniprotkb:SPTSSB(gene name)|psi-mi:SPTSSB(display_short)|uniprotkb:ADMP(gene name synonym)|uniprotkb:C3orf57(gene name synonym)|uniprotkb:SSSPTB(gene name synonym)|uniprotkb:Protein ADMP(gene name synonym)|uniprotkb:Small subunit of serine palmitoyltransferase B(gene name synonym)	psi-mi:sptc3_human(display_long)|uniprotkb:SPTLC3(gene name)|psi-mi:SPTLC3(display_short)|uniprotkb:C20orf38(gene name synonym)|uniprotkb:SPTLC2L(gene name synonym)|uniprotkb:Long chain base biosynthesis protein 2b(gene name synonym)|uniprotkb:Long chain base biosynthesis protein 3(gene name synonym)|uniprotkb:Serine-palmitoyl-CoA transferase 3(gene name synonym)	psi-mi:"MI:0112"(ubiquitin reconstruction)	Han et al. (2009)	pubmed:19416851|doi:10.1073/pnas.0811269106|imex:IM-22435	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15778057|imex:IM-22435-3|dip:DIP-196141E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000196542(gene)|ensembl:ENST00000359175(transcript)|ensembl:ENST00000497137(transcript)|ensembl:ENST00000620149(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017059"(serine C-palmitoyltransferase complex)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:1904220"(regulation of serine C-palmitoyltransferase activity)|interpro:IPR024512|reactome:R-HSA-1660661|refseq:NP_001035189.1|refseq:NP_001307608.1|dip:DIP-60755N	refseq:NP_060797.2|ensembl:ENSG00000172296(gene)|ensembl:ENST00000399002(transcript)|go:"GO:0004758"(serine C-palmitoyltransferase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017059"(serine C-palmitoyltransferase complex)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0046512"(sphingosine biosynthetic process)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:0046520"(sphingoid biosynthetic process)|interpro:IPR001917(Aminotransferase, class-II, pyridoxal-phosphate binding site)|interpro:IPR004839(Aminotransferase, class I and II)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|reactome:R-HSA-1660661|dip:DIP-60753N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/08/06	2017/08/10	rogid:NJFRQVpvKft7NA7ZnHGZdt1x8xY9606	rogid:3BQyhvhH2iX+TrEl+qfLy7UlhG49606	rigid:1KsgwkNY13fzWU1OI2OH9KiqPx8	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9NUV7	uniprotkb:O15269	intact:EBI-11614219|uniprotkb:A2A2I4|uniprotkb:B9EK64|uniprotkb:Q05DQ8|uniprotkb:Q5T1U4|uniprotkb:Q9H1L1|uniprotkb:Q9H1Z0|ensembl:ENSP00000381968	intact:EBI-1044323|uniprotkb:Q5VWB4|uniprotkb:A8K681|uniprotkb:Q96IX6|ensembl:ENSP00000262554	psi-mi:sptc3_human(display_long)|uniprotkb:SPTLC3(gene name)|psi-mi:SPTLC3(display_short)|uniprotkb:C20orf38(gene name synonym)|uniprotkb:SPTLC2L(gene name synonym)|uniprotkb:Long chain base biosynthesis protein 2b(gene name synonym)|uniprotkb:Long chain base biosynthesis protein 3(gene name synonym)|uniprotkb:Serine-palmitoyl-CoA transferase 3(gene name synonym)	psi-mi:sptc1_human(display_long)|uniprotkb:Serine-palmitoyl-CoA transferase 1(gene name synonym)|uniprotkb:Long chain base biosynthesis protein 1(gene name synonym)|uniprotkb:SPTLC1(gene name)|psi-mi:SPTLC1(display_short)|uniprotkb:LCB1(gene name synonym)	psi-mi:"MI:0112"(ubiquitin reconstruction)	Han et al. (2009)	pubmed:19416851|doi:10.1073/pnas.0811269106|imex:IM-22435	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15778007|imex:IM-22435-2|dip:DIP-196134E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060797.2|ensembl:ENSG00000172296(gene)|ensembl:ENST00000399002(transcript)|go:"GO:0004758"(serine C-palmitoyltransferase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017059"(serine C-palmitoyltransferase complex)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0046512"(sphingosine biosynthetic process)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:0046520"(sphingoid biosynthetic process)|interpro:IPR001917(Aminotransferase, class-II, pyridoxal-phosphate binding site)|interpro:IPR004839(Aminotransferase, class I and II)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|reactome:R-HSA-1660661|dip:DIP-60753N	refseq:NP_006406.1|refseq:NP_847894.1|refseq:NP_001268232.1|ensembl:ENSG00000090054(gene)|ensembl:ENST00000262554(transcript)|go:"GO:0004758"(serine C-palmitoyltransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006665"(sphingolipid metabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017059"(serine C-palmitoyltransferase complex)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0035339"(SPOTS complex)|go:"GO:0046512"(sphingosine biosynthetic process)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:1904504"(positive regulation of lipophagy)|go:"GO:1904649"(regulation of fat cell apoptotic process)|interpro:IPR004839(Aminotransferase, class I and II)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|mint:O15269|rcsb pdb:6M4N|rcsb pdb:6M4O|rcsb pdb:7CQI|rcsb pdb:7CQK|rcsb pdb:7K0I|rcsb pdb:7K0J|rcsb pdb:7K0K|rcsb pdb:7K0L|rcsb pdb:7K0M|rcsb pdb:7K0N|rcsb pdb:7K0O|rcsb pdb:7K0P|rcsb pdb:7K0Q|reactome:R-HSA-1660661|dip:DIP-45626N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/08/06	2017/08/10	rogid:3BQyhvhH2iX+TrEl+qfLy7UlhG49606	rogid:M/O7lbdRcUwB+r1wpHj2EtSD+kI9606	rigid:YYGe5WnVwZqOwWzwgHzHxC37ylQ	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9NUV7	uniprotkb:Q969W0	intact:EBI-11614219|uniprotkb:A2A2I4|uniprotkb:B9EK64|uniprotkb:Q05DQ8|uniprotkb:Q5T1U4|uniprotkb:Q9H1L1|uniprotkb:Q9H1Z0|ensembl:ENSP00000381968	intact:EBI-723396|uniprotkb:Q8WTZ7|uniprotkb:B2RD54|ensembl:ENSP00000298130|uniprotkb:D3DS93	psi-mi:sptc3_human(display_long)|uniprotkb:SPTLC3(gene name)|psi-mi:SPTLC3(display_short)|uniprotkb:C20orf38(gene name synonym)|uniprotkb:SPTLC2L(gene name synonym)|uniprotkb:Long chain base biosynthesis protein 2b(gene name synonym)|uniprotkb:Long chain base biosynthesis protein 3(gene name synonym)|uniprotkb:Serine-palmitoyl-CoA transferase 3(gene name synonym)	psi-mi:sptsa_human(display_long)|uniprotkb:SPTSSA(gene name)|psi-mi:SPTSSA(display_short)|uniprotkb:C14orf147(gene name synonym)|uniprotkb:SSSPTA(gene name synonym)|uniprotkb:Small subunit of serine palmitoyltransferase A(gene name synonym)	psi-mi:"MI:0096"(pull down)	Han et al. (2009)	pubmed:19416851|doi:10.1073/pnas.0811269106|imex:IM-22435	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15777983|imex:IM-22435-1|dip:DIP-196132E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060797.2|ensembl:ENSG00000172296(gene)|ensembl:ENST00000399002(transcript)|go:"GO:0004758"(serine C-palmitoyltransferase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017059"(serine C-palmitoyltransferase complex)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0046512"(sphingosine biosynthetic process)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:0046520"(sphingoid biosynthetic process)|interpro:IPR001917(Aminotransferase, class-II, pyridoxal-phosphate binding site)|interpro:IPR004839(Aminotransferase, class I and II)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|reactome:R-HSA-1660661|dip:DIP-60753N	refseq:NP_612145.2|ensembl:ENSG00000165389(gene)|ensembl:ENST00000298130(transcript)|go:"GO:0004758"(serine C-palmitoyltransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0008104"(protein localization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017059"(serine C-palmitoyltransferase complex)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0046513"(ceramide biosynthetic process)|interpro:IPR024512|rcsb pdb:6M4N|rcsb pdb:6M4O|rcsb pdb:7CQI|rcsb pdb:7CQK|rcsb pdb:7K0I|rcsb pdb:7K0J|rcsb pdb:7K0K|rcsb pdb:7K0L|rcsb pdb:7K0M|rcsb pdb:7K0N|rcsb pdb:7K0O|rcsb pdb:7K0P|rcsb pdb:7K0Q|reactome:R-HSA-1660661|dip:DIP-60754N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/08/06	2017/08/10	rogid:3BQyhvhH2iX+TrEl+qfLy7UlhG49606	rogid:zM1bN9vWtTuEJb4b+C4VybXs+8w9606	rigid:iVdQezB+n3aHzDFA2M6RRESuT8Q	false	tandem tag:c-c	ha tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9NUV7	uniprotkb:O15269	intact:EBI-11614219|uniprotkb:A2A2I4|uniprotkb:B9EK64|uniprotkb:Q05DQ8|uniprotkb:Q5T1U4|uniprotkb:Q9H1L1|uniprotkb:Q9H1Z0|ensembl:ENSP00000381968	intact:EBI-1044323|uniprotkb:Q5VWB4|uniprotkb:A8K681|uniprotkb:Q96IX6|ensembl:ENSP00000262554	psi-mi:sptc3_human(display_long)|uniprotkb:SPTLC3(gene name)|psi-mi:SPTLC3(display_short)|uniprotkb:C20orf38(gene name synonym)|uniprotkb:SPTLC2L(gene name synonym)|uniprotkb:Long chain base biosynthesis protein 2b(gene name synonym)|uniprotkb:Long chain base biosynthesis protein 3(gene name synonym)|uniprotkb:Serine-palmitoyl-CoA transferase 3(gene name synonym)	psi-mi:sptc1_human(display_long)|uniprotkb:Serine-palmitoyl-CoA transferase 1(gene name synonym)|uniprotkb:Long chain base biosynthesis protein 1(gene name synonym)|uniprotkb:SPTLC1(gene name)|psi-mi:SPTLC1(display_short)|uniprotkb:LCB1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Han et al. (2009)	pubmed:19416851|doi:10.1073/pnas.0811269106|imex:IM-22435	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15777983|imex:IM-22435-1|dip:DIP-196132E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060797.2|ensembl:ENSG00000172296(gene)|ensembl:ENST00000399002(transcript)|go:"GO:0004758"(serine C-palmitoyltransferase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017059"(serine C-palmitoyltransferase complex)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0046512"(sphingosine biosynthetic process)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:0046520"(sphingoid biosynthetic process)|interpro:IPR001917(Aminotransferase, class-II, pyridoxal-phosphate binding site)|interpro:IPR004839(Aminotransferase, class I and II)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|reactome:R-HSA-1660661|dip:DIP-60753N	refseq:NP_006406.1|refseq:NP_847894.1|refseq:NP_001268232.1|ensembl:ENSG00000090054(gene)|ensembl:ENST00000262554(transcript)|go:"GO:0004758"(serine C-palmitoyltransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006665"(sphingolipid metabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017059"(serine C-palmitoyltransferase complex)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0035339"(SPOTS complex)|go:"GO:0046512"(sphingosine biosynthetic process)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:1904504"(positive regulation of lipophagy)|go:"GO:1904649"(regulation of fat cell apoptotic process)|interpro:IPR004839(Aminotransferase, class I and II)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|mint:O15269|rcsb pdb:6M4N|rcsb pdb:6M4O|rcsb pdb:7CQI|rcsb pdb:7CQK|rcsb pdb:7K0I|rcsb pdb:7K0J|rcsb pdb:7K0K|rcsb pdb:7K0L|rcsb pdb:7K0M|rcsb pdb:7K0N|rcsb pdb:7K0O|rcsb pdb:7K0P|rcsb pdb:7K0Q|reactome:R-HSA-1660661|dip:DIP-45626N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/08/06	2017/08/10	rogid:3BQyhvhH2iX+TrEl+qfLy7UlhG49606	rogid:M/O7lbdRcUwB+r1wpHj2EtSD+kI9606	rigid:iVdQezB+n3aHzDFA2M6RRESuT8Q	false	tandem tag:c-c	ha tag:c-c	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q8NFR3	uniprotkb:O15270	intact:EBI-15778024|ensembl:ENSP00000352097|ensembl:ENSP00000420115|ensembl:ENSP00000480827|uniprotkb:B2R5D3|uniprotkb:D3DNM8|uniprotkb:Q0P5S6	intact:EBI-766136|uniprotkb:Q16685|ensembl:ENSP00000216484	psi-mi:sptsb_human(display_long)|uniprotkb:SPTSSB(gene name)|psi-mi:SPTSSB(display_short)|uniprotkb:ADMP(gene name synonym)|uniprotkb:C3orf57(gene name synonym)|uniprotkb:SSSPTB(gene name synonym)|uniprotkb:Protein ADMP(gene name synonym)|uniprotkb:Small subunit of serine palmitoyltransferase B(gene name synonym)	psi-mi:sptc2_human(display_long)|uniprotkb:Serine-palmitoyl-CoA transferase 2(gene name synonym)|uniprotkb:Long chain base biosynthesis protein 2(gene name synonym)|uniprotkb:SPTLC2(gene name)|psi-mi:SPTLC2(display_short)|uniprotkb:KIAA0526(gene name synonym)|uniprotkb:LCB2(gene name synonym)|uniprotkb:Long chain base biosynthesis protein 2a(gene name synonym)	psi-mi:"MI:0112"(ubiquitin reconstruction)	Han et al. (2009)	pubmed:19416851|doi:10.1073/pnas.0811269106|imex:IM-22435	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15778098|imex:IM-22435-5|dip:DIP-196139E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000196542(gene)|ensembl:ENST00000359175(transcript)|ensembl:ENST00000497137(transcript)|ensembl:ENST00000620149(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017059"(serine C-palmitoyltransferase complex)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:1904220"(regulation of serine C-palmitoyltransferase activity)|interpro:IPR024512|reactome:R-HSA-1660661|refseq:NP_001035189.1|refseq:NP_001307608.1|dip:DIP-60755N	refseq:NP_004854.1|dip:DIP-34604N|ensembl:ENSG00000100596(gene)|ensembl:ENST00000216484(transcript)|go:"GO:0004758"(serine C-palmitoyltransferase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006686"(sphingomyelin biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017059"(serine C-palmitoyltransferase complex)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0046511"(sphinganine biosynthetic process)|go:"GO:0046512"(sphingosine biosynthetic process)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:0060612"(adipose tissue development)|go:"GO:1904504"(positive regulation of lipophagy)|interpro:IPR001917(Aminotransferase, class-II, pyridoxal-phosphate binding site)|interpro:IPR004839(Aminotransferase, class I and II)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|mint:O15270|rcsb pdb:6M4N|rcsb pdb:6M4O|rcsb pdb:7CQI|rcsb pdb:7CQK|rcsb pdb:7K0I|rcsb pdb:7K0J|rcsb pdb:7K0K|rcsb pdb:7K0L|rcsb pdb:7K0M|rcsb pdb:7K0N|rcsb pdb:7K0O|rcsb pdb:7K0P|rcsb pdb:7K0Q|reactome:R-HSA-1660661	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/08/06	2017/08/10	rogid:NJFRQVpvKft7NA7ZnHGZdt1x8xY9606	rogid:9Y8pOwwEej+jqblWkGS0ixnNHLo9606	rigid:lL2HQeh1nVZc2lTgAmiEf4MOuFc	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q969W0	uniprotkb:O15270	intact:EBI-723396|uniprotkb:Q8WTZ7|uniprotkb:B2RD54|ensembl:ENSP00000298130|uniprotkb:D3DS93	intact:EBI-766136|uniprotkb:Q16685|ensembl:ENSP00000216484	psi-mi:sptsa_human(display_long)|uniprotkb:SPTSSA(gene name)|psi-mi:SPTSSA(display_short)|uniprotkb:C14orf147(gene name synonym)|uniprotkb:SSSPTA(gene name synonym)|uniprotkb:Small subunit of serine palmitoyltransferase A(gene name synonym)	psi-mi:sptc2_human(display_long)|uniprotkb:Serine-palmitoyl-CoA transferase 2(gene name synonym)|uniprotkb:Long chain base biosynthesis protein 2(gene name synonym)|uniprotkb:SPTLC2(gene name)|psi-mi:SPTLC2(display_short)|uniprotkb:KIAA0526(gene name synonym)|uniprotkb:LCB2(gene name synonym)|uniprotkb:Long chain base biosynthesis protein 2a(gene name synonym)	psi-mi:"MI:0112"(ubiquitin reconstruction)	Han et al. (2009)	pubmed:19416851|doi:10.1073/pnas.0811269106|imex:IM-22435	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15778166|imex:IM-22435-9|dip:DIP-196138E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_612145.2|ensembl:ENSG00000165389(gene)|ensembl:ENST00000298130(transcript)|go:"GO:0004758"(serine C-palmitoyltransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0008104"(protein localization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017059"(serine C-palmitoyltransferase complex)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0046513"(ceramide biosynthetic process)|interpro:IPR024512|rcsb pdb:6M4N|rcsb pdb:6M4O|rcsb pdb:7CQI|rcsb pdb:7CQK|rcsb pdb:7K0I|rcsb pdb:7K0J|rcsb pdb:7K0K|rcsb pdb:7K0L|rcsb pdb:7K0M|rcsb pdb:7K0N|rcsb pdb:7K0O|rcsb pdb:7K0P|rcsb pdb:7K0Q|reactome:R-HSA-1660661|dip:DIP-60754N	refseq:NP_004854.1|dip:DIP-34604N|ensembl:ENSG00000100596(gene)|ensembl:ENST00000216484(transcript)|go:"GO:0004758"(serine C-palmitoyltransferase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006686"(sphingomyelin biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017059"(serine C-palmitoyltransferase complex)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0046511"(sphinganine biosynthetic process)|go:"GO:0046512"(sphingosine biosynthetic process)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:0060612"(adipose tissue development)|go:"GO:1904504"(positive regulation of lipophagy)|interpro:IPR001917(Aminotransferase, class-II, pyridoxal-phosphate binding site)|interpro:IPR004839(Aminotransferase, class I and II)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|mint:O15270|rcsb pdb:6M4N|rcsb pdb:6M4O|rcsb pdb:7CQI|rcsb pdb:7CQK|rcsb pdb:7K0I|rcsb pdb:7K0J|rcsb pdb:7K0K|rcsb pdb:7K0L|rcsb pdb:7K0M|rcsb pdb:7K0N|rcsb pdb:7K0O|rcsb pdb:7K0P|rcsb pdb:7K0Q|reactome:R-HSA-1660661	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/08/06	2017/08/10	rogid:zM1bN9vWtTuEJb4b+C4VybXs+8w9606	rogid:9Y8pOwwEej+jqblWkGS0ixnNHLo9606	rigid:U+zO5zwL7kYSjCiNIWj/WzSr4jM	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O15270	uniprotkb:O15269	intact:EBI-766136|uniprotkb:Q16685|ensembl:ENSP00000216484	intact:EBI-1044323|uniprotkb:Q5VWB4|uniprotkb:A8K681|uniprotkb:Q96IX6|ensembl:ENSP00000262554	psi-mi:sptc2_human(display_long)|uniprotkb:Serine-palmitoyl-CoA transferase 2(gene name synonym)|uniprotkb:Long chain base biosynthesis protein 2(gene name synonym)|uniprotkb:SPTLC2(gene name)|psi-mi:SPTLC2(display_short)|uniprotkb:KIAA0526(gene name synonym)|uniprotkb:LCB2(gene name synonym)|uniprotkb:Long chain base biosynthesis protein 2a(gene name synonym)	psi-mi:sptc1_human(display_long)|uniprotkb:Serine-palmitoyl-CoA transferase 1(gene name synonym)|uniprotkb:Long chain base biosynthesis protein 1(gene name synonym)|uniprotkb:SPTLC1(gene name)|psi-mi:SPTLC1(display_short)|uniprotkb:LCB1(gene name synonym)	psi-mi:"MI:0112"(ubiquitin reconstruction)	Han et al. (2009)	pubmed:19416851|doi:10.1073/pnas.0811269106|imex:IM-22435	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15778149|imex:IM-22435-8|dip:DIP-196133E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004854.1|dip:DIP-34604N|ensembl:ENSG00000100596(gene)|ensembl:ENST00000216484(transcript)|go:"GO:0004758"(serine C-palmitoyltransferase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006686"(sphingomyelin biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017059"(serine C-palmitoyltransferase complex)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0046511"(sphinganine biosynthetic process)|go:"GO:0046512"(sphingosine biosynthetic process)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:0060612"(adipose tissue development)|go:"GO:1904504"(positive regulation of lipophagy)|interpro:IPR001917(Aminotransferase, class-II, pyridoxal-phosphate binding site)|interpro:IPR004839(Aminotransferase, class I and II)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|mint:O15270|rcsb pdb:6M4N|rcsb pdb:6M4O|rcsb pdb:7CQI|rcsb pdb:7CQK|rcsb pdb:7K0I|rcsb pdb:7K0J|rcsb pdb:7K0K|rcsb pdb:7K0L|rcsb pdb:7K0M|rcsb pdb:7K0N|rcsb pdb:7K0O|rcsb pdb:7K0P|rcsb pdb:7K0Q|reactome:R-HSA-1660661	refseq:NP_006406.1|refseq:NP_847894.1|refseq:NP_001268232.1|ensembl:ENSG00000090054(gene)|ensembl:ENST00000262554(transcript)|go:"GO:0004758"(serine C-palmitoyltransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006665"(sphingolipid metabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017059"(serine C-palmitoyltransferase complex)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0035339"(SPOTS complex)|go:"GO:0046512"(sphingosine biosynthetic process)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:1904504"(positive regulation of lipophagy)|go:"GO:1904649"(regulation of fat cell apoptotic process)|interpro:IPR004839(Aminotransferase, class I and II)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|mint:O15269|rcsb pdb:6M4N|rcsb pdb:6M4O|rcsb pdb:7CQI|rcsb pdb:7CQK|rcsb pdb:7K0I|rcsb pdb:7K0J|rcsb pdb:7K0K|rcsb pdb:7K0L|rcsb pdb:7K0M|rcsb pdb:7K0N|rcsb pdb:7K0O|rcsb pdb:7K0P|rcsb pdb:7K0Q|reactome:R-HSA-1660661|dip:DIP-45626N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/08/06	2017/08/10	rogid:9Y8pOwwEej+jqblWkGS0ixnNHLo9606	rogid:M/O7lbdRcUwB+r1wpHj2EtSD+kI9606	rigid:gvA53TuRiemwev1eeHjdXfSgQVY	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q969W0	uniprotkb:O15269	intact:EBI-723396|uniprotkb:Q8WTZ7|uniprotkb:B2RD54|ensembl:ENSP00000298130|uniprotkb:D3DS93	intact:EBI-1044323|uniprotkb:Q5VWB4|uniprotkb:A8K681|uniprotkb:Q96IX6|ensembl:ENSP00000262554	psi-mi:sptsa_human(display_long)|uniprotkb:SPTSSA(gene name)|psi-mi:SPTSSA(display_short)|uniprotkb:C14orf147(gene name synonym)|uniprotkb:SSSPTA(gene name synonym)|uniprotkb:Small subunit of serine palmitoyltransferase A(gene name synonym)	psi-mi:sptc1_human(display_long)|uniprotkb:Serine-palmitoyl-CoA transferase 1(gene name synonym)|uniprotkb:Long chain base biosynthesis protein 1(gene name synonym)|uniprotkb:SPTLC1(gene name)|psi-mi:SPTLC1(display_short)|uniprotkb:LCB1(gene name synonym)	psi-mi:"MI:0112"(ubiquitin reconstruction)	Han et al. (2009)	pubmed:19416851|doi:10.1073/pnas.0811269106|imex:IM-22435	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15778132|imex:IM-22435-7|dip:DIP-196135E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_612145.2|ensembl:ENSG00000165389(gene)|ensembl:ENST00000298130(transcript)|go:"GO:0004758"(serine C-palmitoyltransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0008104"(protein localization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017059"(serine C-palmitoyltransferase complex)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0046513"(ceramide biosynthetic process)|interpro:IPR024512|rcsb pdb:6M4N|rcsb pdb:6M4O|rcsb pdb:7CQI|rcsb pdb:7CQK|rcsb pdb:7K0I|rcsb pdb:7K0J|rcsb pdb:7K0K|rcsb pdb:7K0L|rcsb pdb:7K0M|rcsb pdb:7K0N|rcsb pdb:7K0O|rcsb pdb:7K0P|rcsb pdb:7K0Q|reactome:R-HSA-1660661|dip:DIP-60754N	refseq:NP_006406.1|refseq:NP_847894.1|refseq:NP_001268232.1|ensembl:ENSG00000090054(gene)|ensembl:ENST00000262554(transcript)|go:"GO:0004758"(serine C-palmitoyltransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006665"(sphingolipid metabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017059"(serine C-palmitoyltransferase complex)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0035339"(SPOTS complex)|go:"GO:0046512"(sphingosine biosynthetic process)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:1904504"(positive regulation of lipophagy)|go:"GO:1904649"(regulation of fat cell apoptotic process)|interpro:IPR004839(Aminotransferase, class I and II)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|mint:O15269|rcsb pdb:6M4N|rcsb pdb:6M4O|rcsb pdb:7CQI|rcsb pdb:7CQK|rcsb pdb:7K0I|rcsb pdb:7K0J|rcsb pdb:7K0K|rcsb pdb:7K0L|rcsb pdb:7K0M|rcsb pdb:7K0N|rcsb pdb:7K0O|rcsb pdb:7K0P|rcsb pdb:7K0Q|reactome:R-HSA-1660661|dip:DIP-45626N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/08/06	2017/08/10	rogid:zM1bN9vWtTuEJb4b+C4VybXs+8w9606	rogid:M/O7lbdRcUwB+r1wpHj2EtSD+kI9606	rigid:5LSEYbpLZpuIXtTV+8ZZfN3uds8	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q969W0	uniprotkb:Q9NUV7	intact:EBI-723396|uniprotkb:Q8WTZ7|uniprotkb:B2RD54|ensembl:ENSP00000298130|uniprotkb:D3DS93	intact:EBI-11614219|uniprotkb:A2A2I4|uniprotkb:B9EK64|uniprotkb:Q05DQ8|uniprotkb:Q5T1U4|uniprotkb:Q9H1L1|uniprotkb:Q9H1Z0|ensembl:ENSP00000381968	psi-mi:sptsa_human(display_long)|uniprotkb:SPTSSA(gene name)|psi-mi:SPTSSA(display_short)|uniprotkb:C14orf147(gene name synonym)|uniprotkb:SSSPTA(gene name synonym)|uniprotkb:Small subunit of serine palmitoyltransferase A(gene name synonym)	psi-mi:sptc3_human(display_long)|uniprotkb:SPTLC3(gene name)|psi-mi:SPTLC3(display_short)|uniprotkb:C20orf38(gene name synonym)|uniprotkb:SPTLC2L(gene name synonym)|uniprotkb:Long chain base biosynthesis protein 2b(gene name synonym)|uniprotkb:Long chain base biosynthesis protein 3(gene name synonym)|uniprotkb:Serine-palmitoyl-CoA transferase 3(gene name synonym)	psi-mi:"MI:0112"(ubiquitin reconstruction)	Han et al. (2009)	pubmed:19416851|doi:10.1073/pnas.0811269106|imex:IM-22435	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15778115|imex:IM-22435-6|dip:DIP-196140E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_612145.2|ensembl:ENSG00000165389(gene)|ensembl:ENST00000298130(transcript)|go:"GO:0004758"(serine C-palmitoyltransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0008104"(protein localization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017059"(serine C-palmitoyltransferase complex)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0046513"(ceramide biosynthetic process)|interpro:IPR024512|rcsb pdb:6M4N|rcsb pdb:6M4O|rcsb pdb:7CQI|rcsb pdb:7CQK|rcsb pdb:7K0I|rcsb pdb:7K0J|rcsb pdb:7K0K|rcsb pdb:7K0L|rcsb pdb:7K0M|rcsb pdb:7K0N|rcsb pdb:7K0O|rcsb pdb:7K0P|rcsb pdb:7K0Q|reactome:R-HSA-1660661|dip:DIP-60754N	refseq:NP_060797.2|ensembl:ENSG00000172296(gene)|ensembl:ENST00000399002(transcript)|go:"GO:0004758"(serine C-palmitoyltransferase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017059"(serine C-palmitoyltransferase complex)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0046512"(sphingosine biosynthetic process)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:0046520"(sphingoid biosynthetic process)|interpro:IPR001917(Aminotransferase, class-II, pyridoxal-phosphate binding site)|interpro:IPR004839(Aminotransferase, class I and II)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|reactome:R-HSA-1660661|dip:DIP-60753N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/08/06	2017/08/10	rogid:zM1bN9vWtTuEJb4b+C4VybXs+8w9606	rogid:3BQyhvhH2iX+TrEl+qfLy7UlhG49606	rigid:srepIZE0uU4pR2487UzFGG9/Cj4	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8NFR3	uniprotkb:O15269	intact:EBI-15778024|ensembl:ENSP00000352097|ensembl:ENSP00000420115|ensembl:ENSP00000480827|uniprotkb:B2R5D3|uniprotkb:D3DNM8|uniprotkb:Q0P5S6	intact:EBI-1044323|uniprotkb:Q5VWB4|uniprotkb:A8K681|uniprotkb:Q96IX6|ensembl:ENSP00000262554	psi-mi:sptsb_human(display_long)|uniprotkb:SPTSSB(gene name)|psi-mi:SPTSSB(display_short)|uniprotkb:ADMP(gene name synonym)|uniprotkb:C3orf57(gene name synonym)|uniprotkb:SSSPTB(gene name synonym)|uniprotkb:Protein ADMP(gene name synonym)|uniprotkb:Small subunit of serine palmitoyltransferase B(gene name synonym)	psi-mi:sptc1_human(display_long)|uniprotkb:Serine-palmitoyl-CoA transferase 1(gene name synonym)|uniprotkb:Long chain base biosynthesis protein 1(gene name synonym)|uniprotkb:SPTLC1(gene name)|psi-mi:SPTLC1(display_short)|uniprotkb:LCB1(gene name synonym)	psi-mi:"MI:0112"(ubiquitin reconstruction)	Han et al. (2009)	pubmed:19416851|doi:10.1073/pnas.0811269106|imex:IM-22435	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15778183|imex:IM-22435-10|dip:DIP-196136E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000196542(gene)|ensembl:ENST00000359175(transcript)|ensembl:ENST00000497137(transcript)|ensembl:ENST00000620149(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017059"(serine C-palmitoyltransferase complex)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:1904220"(regulation of serine C-palmitoyltransferase activity)|interpro:IPR024512|reactome:R-HSA-1660661|refseq:NP_001035189.1|refseq:NP_001307608.1|dip:DIP-60755N	refseq:NP_006406.1|refseq:NP_847894.1|refseq:NP_001268232.1|ensembl:ENSG00000090054(gene)|ensembl:ENST00000262554(transcript)|go:"GO:0004758"(serine C-palmitoyltransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006665"(sphingolipid metabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017059"(serine C-palmitoyltransferase complex)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0035339"(SPOTS complex)|go:"GO:0046512"(sphingosine biosynthetic process)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:1904504"(positive regulation of lipophagy)|go:"GO:1904649"(regulation of fat cell apoptotic process)|interpro:IPR004839(Aminotransferase, class I and II)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|mint:O15269|rcsb pdb:6M4N|rcsb pdb:6M4O|rcsb pdb:7CQI|rcsb pdb:7CQK|rcsb pdb:7K0I|rcsb pdb:7K0J|rcsb pdb:7K0K|rcsb pdb:7K0L|rcsb pdb:7K0M|rcsb pdb:7K0N|rcsb pdb:7K0O|rcsb pdb:7K0P|rcsb pdb:7K0Q|reactome:R-HSA-1660661|dip:DIP-45626N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/08/06	2017/08/10	rogid:NJFRQVpvKft7NA7ZnHGZdt1x8xY9606	rogid:M/O7lbdRcUwB+r1wpHj2EtSD+kI9606	rigid:2k60faq4RB3JCb9wPZ16YXMKvXo	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)