#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P63239	uniprotkb:P63239	intact:EBI-15770815|ensembl:ENSMUSP00000022075|uniprotkb:P21662|uniprotkb:P22546	intact:EBI-15770815|ensembl:ENSMUSP00000022075|uniprotkb:P21662|uniprotkb:P22546	psi-mi:nec1_mouse(display_long)|uniprotkb:Pcsk1(gene name)|psi-mi:Pcsk1(display_short)|uniprotkb:Att-1(gene name synonym)|uniprotkb:Nec-1(gene name synonym)|uniprotkb:Nec1(gene name synonym)|uniprotkb:Furin homolog(gene name synonym)|uniprotkb:PC3(gene name synonym)|uniprotkb:Prohormone convertase 1(gene name synonym)|uniprotkb:Propeptide-processing protease(gene name synonym)|uniprotkb:Proprotein convertase 1(gene name synonym)	psi-mi:nec1_mouse(display_long)|uniprotkb:Pcsk1(gene name)|psi-mi:Pcsk1(display_short)|uniprotkb:Att-1(gene name synonym)|uniprotkb:Nec-1(gene name synonym)|uniprotkb:Nec1(gene name synonym)|uniprotkb:Furin homolog(gene name synonym)|uniprotkb:PC3(gene name synonym)|uniprotkb:Prohormone convertase 1(gene name synonym)|uniprotkb:Propeptide-processing protease(gene name synonym)|uniprotkb:Proprotein convertase 1(gene name synonym)	psi-mi:"MI:0077"(nuclear magnetic resonance)	Dikeakos et al. (2009)	pubmed:19376969|doi:10.1073/pnas.0809576106|imex:IM-14718	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15770869|imex:IM-14718-1|dip:DIP-103804E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000021587(gene)|ensembl:ENSMUST00000022075(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016020"(membrane)|go:"GO:0016485"(protein processing)|go:"GO:0016486"(peptide hormone processing)|go:"GO:0030133"(transport vesicle)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043043"(peptide biosynthetic process)|interpro:IPR000209(Peptidase S8 and S53, subtilisin, kexin, sedolisin)|interpro:IPR002884(Proprotein convertase, P)|interpro:IPR008979(Galactose-binding like)|interpro:IPR015500(Peptidase S8, subtilisin-related)|interpro:IPR022005|interpro:IPR022398|interpro:IPR023827|interpro:IPR023828|interpro:IPR032815|interpro:IPR034182|interpro:IPR036852|interpro:IPR038466|rcsb pdb:1KN6|rcsb pdb:2KDT|rcsb pdb:2KE3|reactome:R-MMU-209952|reactome:R-MMU-422085|refseq:NP_038656.1|refseq:XP_006517216.1|refseq:XP_006517217.1|refseq:XP_006517218.1|dip:DIP-48841N	ensembl:ENSMUSG00000021587(gene)|ensembl:ENSMUST00000022075(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016020"(membrane)|go:"GO:0016485"(protein processing)|go:"GO:0016486"(peptide hormone processing)|go:"GO:0030133"(transport vesicle)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043043"(peptide biosynthetic process)|interpro:IPR000209(Peptidase S8 and S53, subtilisin, kexin, sedolisin)|interpro:IPR002884(Proprotein convertase, P)|interpro:IPR008979(Galactose-binding like)|interpro:IPR015500(Peptidase S8, subtilisin-related)|interpro:IPR022005|interpro:IPR022398|interpro:IPR023827|interpro:IPR023828|interpro:IPR032815|interpro:IPR034182|interpro:IPR036852|interpro:IPR038466|rcsb pdb:1KN6|rcsb pdb:2KDT|rcsb pdb:2KE3|reactome:R-MMU-209952|reactome:R-MMU-422085|refseq:NP_038656.1|refseq:XP_006517216.1|refseq:XP_006517217.1|refseq:XP_006517218.1|dip:DIP-48841N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:562(ecolx)|taxid:562(Escherichia coli)	-	2017/08/06	2017/08/10	rogid:tpaxqmY+OFCzDWTxte4mc0YIO3o10090	rogid:tpaxqmY+OFCzDWTxte4mc0YIO3o10090	rigid:nbeH3sWvQBb7wxrO4nXPkOEKxUw	false	binding-associated region:711-753	binding-associated region:711-753	-	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P63239	uniprotkb:P63239	intact:EBI-15770815|ensembl:ENSMUSP00000022075|uniprotkb:P21662|uniprotkb:P22546	intact:EBI-15770815|ensembl:ENSMUSP00000022075|uniprotkb:P21662|uniprotkb:P22546	psi-mi:nec1_mouse(display_long)|uniprotkb:Pcsk1(gene name)|psi-mi:Pcsk1(display_short)|uniprotkb:Att-1(gene name synonym)|uniprotkb:Nec-1(gene name synonym)|uniprotkb:Nec1(gene name synonym)|uniprotkb:Furin homolog(gene name synonym)|uniprotkb:PC3(gene name synonym)|uniprotkb:Prohormone convertase 1(gene name synonym)|uniprotkb:Propeptide-processing protease(gene name synonym)|uniprotkb:Proprotein convertase 1(gene name synonym)	psi-mi:nec1_mouse(display_long)|uniprotkb:Pcsk1(gene name)|psi-mi:Pcsk1(display_short)|uniprotkb:Att-1(gene name synonym)|uniprotkb:Nec-1(gene name synonym)|uniprotkb:Nec1(gene name synonym)|uniprotkb:Furin homolog(gene name synonym)|uniprotkb:PC3(gene name synonym)|uniprotkb:Prohormone convertase 1(gene name synonym)|uniprotkb:Propeptide-processing protease(gene name synonym)|uniprotkb:Proprotein convertase 1(gene name synonym)	psi-mi:"MI:0028"(cosedimentation in solution)	Dikeakos et al. (2009)	pubmed:19376969|doi:10.1073/pnas.0809576106|imex:IM-14718	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15770887|imex:IM-14718-2|dip:DIP-103804E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000021587(gene)|ensembl:ENSMUST00000022075(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016020"(membrane)|go:"GO:0016485"(protein processing)|go:"GO:0016486"(peptide hormone processing)|go:"GO:0030133"(transport vesicle)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043043"(peptide biosynthetic process)|interpro:IPR000209(Peptidase S8 and S53, subtilisin, kexin, sedolisin)|interpro:IPR002884(Proprotein convertase, P)|interpro:IPR008979(Galactose-binding like)|interpro:IPR015500(Peptidase S8, subtilisin-related)|interpro:IPR022005|interpro:IPR022398|interpro:IPR023827|interpro:IPR023828|interpro:IPR032815|interpro:IPR034182|interpro:IPR036852|interpro:IPR038466|rcsb pdb:1KN6|rcsb pdb:2KDT|rcsb pdb:2KE3|reactome:R-MMU-209952|reactome:R-MMU-422085|refseq:NP_038656.1|refseq:XP_006517216.1|refseq:XP_006517217.1|refseq:XP_006517218.1|dip:DIP-48841N	ensembl:ENSMUSG00000021587(gene)|ensembl:ENSMUST00000022075(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016020"(membrane)|go:"GO:0016485"(protein processing)|go:"GO:0016486"(peptide hormone processing)|go:"GO:0030133"(transport vesicle)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043043"(peptide biosynthetic process)|interpro:IPR000209(Peptidase S8 and S53, subtilisin, kexin, sedolisin)|interpro:IPR002884(Proprotein convertase, P)|interpro:IPR008979(Galactose-binding like)|interpro:IPR015500(Peptidase S8, subtilisin-related)|interpro:IPR022005|interpro:IPR022398|interpro:IPR023827|interpro:IPR023828|interpro:IPR032815|interpro:IPR034182|interpro:IPR036852|interpro:IPR038466|rcsb pdb:1KN6|rcsb pdb:2KDT|rcsb pdb:2KE3|reactome:R-MMU-209952|reactome:R-MMU-422085|refseq:NP_038656.1|refseq:XP_006517216.1|refseq:XP_006517217.1|refseq:XP_006517218.1|dip:DIP-48841N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:562(ecolx)|taxid:562(Escherichia coli)	-	2017/08/06	2017/08/10	rogid:tpaxqmY+OFCzDWTxte4mc0YIO3o10090	rogid:tpaxqmY+OFCzDWTxte4mc0YIO3o10090	rigid:nbeH3sWvQBb7wxrO4nXPkOEKxUw	false	binding-associated region:711-753	binding-associated region:711-753	-	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)