#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P04899	uniprotkb:P63212	intact:EBI-353997|uniprotkb:Q8IZ71|intact:EBI-2563889|uniprotkb:B4DYA0|intact:EBI-4404691|uniprotkb:Q6B6N3|uniprotkb:B3KTZ0|uniprotkb:B4E2X5|ensembl:ENSP00000312999	intact:EBI-1036424|uniprotkb:P16874|uniprotkb:Q2KI31|uniprotkb:Q61013|uniprotkb:Q9TS47|ensembl:ENSBTAP00000003959	psi-mi:gnai2_human(display_long)|uniprotkb:GNAI2(gene name)|psi-mi:GNAI2(display_short)|uniprotkb:GNAI2B(gene name synonym)|uniprotkb:Adenylate cyclase-inhibiting G alpha protein(gene name synonym)	psi-mi:gbg2_bovin(display_long)|uniprotkb:GNG2(gene name)|psi-mi:GNG2(display_short)|uniprotkb:G gamma-I(gene name synonym)	psi-mi:"MI:0096"(pull down)	Orth et al. (2009)	pubmed:19369209|doi:10.1073/pnas.0900160106|imex:IM-14715	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15770201|imex:IM-14715-1|dip:DIP-103797E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002061.1|refseq:NP_001269546.1|refseq:NP_001269549.1|refseq:NP_001269547.1|refseq:NP_001269548.1|refseq:NP_001159897.1|dip:DIP-602N|ensembl:ENSG00000114353(gene)|ensembl:ENST00000313601(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001973"(G protein-coupled adenosine receptor signaling pathway)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007194"(negative regulation of adenylate cyclase activity)|go:"GO:0007213"(G protein-coupled acetylcholine receptor signaling pathway)|go:"GO:0007214"(gamma-aminobutyric acid signaling pathway)|go:"GO:0007584"(response to nutrient)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0005737"(cytoplasm)|go:"GO:0030496"(midbody)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0032930"(positive regulation of superoxide anion generation)|go:"GO:0033864"("positive regulation of NAD(P)H oxidase activity")|go:"GO:0035810"(positive regulation of urine volume)|go:"GO:0035815"(positive regulation of renal sodium excretion)|go:"GO:0044297"(cell body)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045955"(negative regulation of calcium ion-dependent exocytosis)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0046872"(metal ion binding)|go:"GO:0050805"(negative regulation of synaptic transmission)|go:"GO:0051301"(cell division)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0140199"(negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process)|go:"GO:1903561"(extracellular vesicle)|go:"GO:1903614"(negative regulation of protein tyrosine phosphatase activity)|go:"GO:0030425"(dendrite)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:2000179"(positive regulation of neural precursor cell proliferation)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR001408(G-protein alpha subunit, group I)|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|rcsb pdb:6D9H|reactome:R-HSA-170670|reactome:R-HSA-392170|reactome:R-HSA-400042|reactome:R-HSA-418555|reactome:R-HSA-418594|reactome:R-HSA-418597|reactome:R-HSA-422356|reactome:R-HSA-9009391|reactome:R-HSA-9660821|mint:P04899	refseq:NP_776497.1|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007191"(adenylate cyclase-activating dopamine receptor signaling pathway)|go:"GO:0016020"(membrane)|go:"GO:0031680"(G-protein beta/gamma-subunit complex)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071870"(cellular response to catecholamine stimulus)|interpro:IPR001770(G-protein, gamma subunit)|interpro:IPR015898(G-protein, gamma-like subunit)|interpro:IPR036284|rcsb pdb:1GG2|rcsb pdb:1GP2|rcsb pdb:1OMW|rcsb pdb:1XHM|rcsb pdb:2BCJ|rcsb pdb:3AH8|rcsb pdb:3CIK|rcsb pdb:3KRW|rcsb pdb:3KRX|rcsb pdb:3SN6|rcsb pdb:3UZS|rcsb pdb:3V5W|rcsb pdb:4MK0|rcsb pdb:4PNK|rcsb pdb:5TDH|rcsb pdb:5VAI|rcsb pdb:5WG3|rcsb pdb:5WG4|rcsb pdb:5WG5|rcsb pdb:6C2Y|rcsb pdb:6CMO|rcsb pdb:6LPB|rcsb pdb:6NBF|rcsb pdb:6NBH|rcsb pdb:6NBI|rcsb pdb:6PCV|rcsb pdb:6U7C|rcsb pdb:7BW0|rcsb pdb:7BZ2|rcsb pdb:7CZ5|rcsb pdb:7D3S|rcsb pdb:7D68|rcsb pdb:7DHI|rcsb pdb:7DHR|rcsb pdb:7JJO|rcsb pdb:3PSC|rcsb pdb:3PVU|rcsb pdb:3PVW|rcsb pdb:7LJC|rcsb pdb:7LJD|reactome:R-BTA-392170|reactome:R-BTA-416476|reactome:R-BTA-418594|reactome:R-BTA-418597|reactome:R-BTA-428930|reactome:R-BTA-456926|reactome:R-BTA-6814122|reactome:R-BTA-392451|ensembl:ENSBTAG00000003043(gene)|ensembl:ENSBTAT00000003959(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005834"(heterotrimeric G-protein complex)|refseq:XP_005211711.1|refseq:XP_010807541.1|dip:DIP-586N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/06	2017/08/10	rogid:Mi3PAXudkdPb375bOi7luNAmUaU9606	rogid:8asTjDtSU6sCPSMwcXMbV340Rt49913	rigid:/YXUfJJEMObcuHk4l/8LDJWaZWw	false	glutathione s tranferase tag:n-n	35s radiolabel:?-?	-	-	psi-mi:"MI:0833"(autoradiography)	psi-mi:"MI:0833"(autoradiography)
uniprotkb:P04899	uniprotkb:P62871	intact:EBI-353997|uniprotkb:Q8IZ71|intact:EBI-2563889|uniprotkb:B4DYA0|intact:EBI-4404691|uniprotkb:Q6B6N3|uniprotkb:B3KTZ0|uniprotkb:B4E2X5|ensembl:ENSP00000312999	intact:EBI-357141|ensembl:ENSBTAP00000000259|ensembl:ENSBTAP00000042481|uniprotkb:P04901|uniprotkb:P04697|uniprotkb:Q3MHF1	psi-mi:gnai2_human(display_long)|uniprotkb:GNAI2(gene name)|psi-mi:GNAI2(display_short)|uniprotkb:GNAI2B(gene name synonym)|uniprotkb:Adenylate cyclase-inhibiting G alpha protein(gene name synonym)	psi-mi:gbb1_bovin(display_long)|uniprotkb:GNB1(gene name)|psi-mi:GNB1(display_short)|uniprotkb:Transducin beta chain 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Orth et al. (2009)	pubmed:19369209|doi:10.1073/pnas.0900160106|imex:IM-14715	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15770201|imex:IM-14715-1|dip:DIP-103797E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002061.1|refseq:NP_001269546.1|refseq:NP_001269549.1|refseq:NP_001269547.1|refseq:NP_001269548.1|refseq:NP_001159897.1|dip:DIP-602N|ensembl:ENSG00000114353(gene)|ensembl:ENST00000313601(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001973"(G protein-coupled adenosine receptor signaling pathway)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007194"(negative regulation of adenylate cyclase activity)|go:"GO:0007213"(G protein-coupled acetylcholine receptor signaling pathway)|go:"GO:0007214"(gamma-aminobutyric acid signaling pathway)|go:"GO:0007584"(response to nutrient)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0005737"(cytoplasm)|go:"GO:0030496"(midbody)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0032930"(positive regulation of superoxide anion generation)|go:"GO:0033864"("positive regulation of NAD(P)H oxidase activity")|go:"GO:0035810"(positive regulation of urine volume)|go:"GO:0035815"(positive regulation of renal sodium excretion)|go:"GO:0044297"(cell body)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045955"(negative regulation of calcium ion-dependent exocytosis)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0046872"(metal ion binding)|go:"GO:0050805"(negative regulation of synaptic transmission)|go:"GO:0051301"(cell division)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0140199"(negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process)|go:"GO:1903561"(extracellular vesicle)|go:"GO:1903614"(negative regulation of protein tyrosine phosphatase activity)|go:"GO:0030425"(dendrite)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:2000179"(positive regulation of neural precursor cell proliferation)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR001408(G-protein alpha subunit, group I)|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|rcsb pdb:6D9H|reactome:R-HSA-170670|reactome:R-HSA-392170|reactome:R-HSA-400042|reactome:R-HSA-418555|reactome:R-HSA-418594|reactome:R-HSA-418597|reactome:R-HSA-422356|reactome:R-HSA-9009391|reactome:R-HSA-9660821|mint:P04899	ensembl:ENSBTAG00000000215(gene)|ensembl:ENSBTAT00000000259(transcript)|ensembl:ENSBTAT00000045065(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007191"(adenylate cyclase-activating dopamine receptor signaling pathway)|go:"GO:0016020"(membrane)|go:"GO:0031682"(G-protein gamma-subunit binding)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071870"(cellular response to catecholamine stimulus)|go:"GO:0097381"(photoreceptor disc membrane)|interpro:IPR001632(G-protein, beta subunit)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016346(Guanine nucleotide-binding protein, beta subunit)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P62871|rcsb pdb:1A0R|rcsb pdb:1B9X|rcsb pdb:1B9Y|rcsb pdb:1GG2|rcsb pdb:1GOT|rcsb pdb:1GP2|rcsb pdb:1OMW|rcsb pdb:1TBG|rcsb pdb:1XHM|rcsb pdb:2BCJ|rcsb pdb:2TRC|rcsb pdb:3AH8|rcsb pdb:3CIK|rcsb pdb:3KRW|rcsb pdb:3KRX|rcsb pdb:3PSC|rcsb pdb:3PVU|rcsb pdb:3PVW|rcsb pdb:3UZS|rcsb pdb:3V5W|rcsb pdb:4MK0|rcsb pdb:5KDO|rcsb pdb:5WG3|rcsb pdb:5WG4|rcsb pdb:5WG5|rcsb pdb:6B20|rcsb pdb:6C2Y|rcsb pdb:6OY9|rcsb pdb:6OYA|rcsb pdb:6PCV|rcsb pdb:6QNO|rcsb pdb:6U7C|rcsb pdb:7BZ2|rcsb pdb:7D68|rcsb pdb:7DHI|rcsb pdb:7DHR|rcsb pdb:7JJO|rcsb pdb:7O7F|refseq:NP_786971.2|dip:DIP-29227N|refseq:XP_010811610.1|refseq:XP_005217074.1	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/06	2017/08/10	rogid:Mi3PAXudkdPb375bOi7luNAmUaU9606	rogid:zP/G70MXiSQpzbyyWFTWrJFQENk9913	rigid:/YXUfJJEMObcuHk4l/8LDJWaZWw	false	glutathione s tranferase tag:n-n	35s radiolabel:?-?	-	-	psi-mi:"MI:0833"(autoradiography)	psi-mi:"MI:0833"(autoradiography)