#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P36404 uniprotkb:Q9Y2Y0 intact:EBI-752365|uniprotkb:Q9BUK8|uniprotkb:G3V184|ensembl:ENSP00000246747|ensembl:ENSP00000436021 intact:EBI-3449344|uniprotkb:Q504R0|uniprotkb:B3KQJ5|ensembl:ENSP00000219204 psi-mi:arl2_human(display_long)|uniprotkb:ARL2(gene name)|psi-mi:ARL2(display_short) psi-mi:ar2bp_human(display_long)|uniprotkb:ARL2BP(gene name)|psi-mi:ARL2BP(display_short)|uniprotkb:BART(gene name synonym)|uniprotkb:BART1(gene name synonym)|uniprotkb:Binder of ARF2 protein 1(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Zhang et al. (2009) pubmed:19368893|doi:10.1016/j.str.2009.01.014|imex:IM-11776 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15769577|imex:IM-11776-1|dip:DIP-102551E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001186674.1|refseq:NP_001658.2|dip:DIP-47535N|ensembl:ENSG00000213465(gene)|ensembl:ENST00000246747(transcript)|ensembl:ENST00000529384(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005095"(GTPase inhibitor activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007021"(tubulin complex assembly)|go:"GO:0007098"(centrosome cycle)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019003"(GDP binding)|go:"GO:0031113"(regulation of microtubule polymerization)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0070830"(bicellular tight junction assembly)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|interpro:IPR044612|mint:P36404|rcsb pdb:3DOE|rcsb pdb:3DOF|reactome:R-HSA-389977|reactome:R-HSA-83936|reactome:R-HSA-9648002 refseq:NP_036238.1|dip:DIP-48323N|ensembl:ENSG00000102931(gene)|ensembl:ENST00000219204(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0007165"(signal transduction)|go:"GO:0030496"(midbody)|go:"GO:0030695"(GTPase regulator activity)|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0051457"(maintenance of protein location in nucleus)|interpro:IPR023379|interpro:IPR038849|interpro:IPR042541|rcsb pdb:2K9A|rcsb pdb:3DOE|rcsb pdb:3DOF|reactome:R-HSA-83936 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/06 2017/08/10 rogid:ArQxx65a8vITU2O0Kr0Qo0hqiqU9606 rogid:w0KrwWvWCYKloGK+8fPwAheajP09606 rigid:o0sgvz4UxjHJp1HAGGupm75EkdE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P36404 uniprotkb:Q9Y2Y0 intact:EBI-752365|uniprotkb:Q9BUK8|uniprotkb:G3V184|ensembl:ENSP00000246747|ensembl:ENSP00000436021 intact:EBI-3449344|uniprotkb:Q504R0|uniprotkb:B3KQJ5|ensembl:ENSP00000219204 psi-mi:arl2_human(display_long)|uniprotkb:ARL2(gene name)|psi-mi:ARL2(display_short) psi-mi:ar2bp_human(display_long)|uniprotkb:ARL2BP(gene name)|psi-mi:ARL2BP(display_short)|uniprotkb:BART(gene name synonym)|uniprotkb:BART1(gene name synonym)|uniprotkb:Binder of ARF2 protein 1(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Zhang et al. (2009) pubmed:19368893|doi:10.1016/j.str.2009.01.014|imex:IM-11776 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15769596|imex:IM-11776-2|dip:DIP-102551E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001186674.1|refseq:NP_001658.2|dip:DIP-47535N|ensembl:ENSG00000213465(gene)|ensembl:ENST00000246747(transcript)|ensembl:ENST00000529384(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005095"(GTPase inhibitor activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007021"(tubulin complex assembly)|go:"GO:0007098"(centrosome cycle)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019003"(GDP binding)|go:"GO:0031113"(regulation of microtubule polymerization)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0070830"(bicellular tight junction assembly)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|interpro:IPR044612|mint:P36404|rcsb pdb:3DOE|rcsb pdb:3DOF|reactome:R-HSA-389977|reactome:R-HSA-83936|reactome:R-HSA-9648002 refseq:NP_036238.1|dip:DIP-48323N|ensembl:ENSG00000102931(gene)|ensembl:ENST00000219204(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0007165"(signal transduction)|go:"GO:0030496"(midbody)|go:"GO:0030695"(GTPase regulator activity)|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0051457"(maintenance of protein location in nucleus)|interpro:IPR023379|interpro:IPR038849|interpro:IPR042541|rcsb pdb:2K9A|rcsb pdb:3DOE|rcsb pdb:3DOF|reactome:R-HSA-83936 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/06 2017/08/10 rogid:ArQxx65a8vITU2O0Kr0Qo0hqiqU9606 rogid:w0KrwWvWCYKloGK+8fPwAheajP09606 rigid:o0sgvz4UxjHJp1HAGGupm75EkdE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P36404 uniprotkb:Q9Y2Y0 intact:EBI-752365|uniprotkb:Q9BUK8|uniprotkb:G3V184|ensembl:ENSP00000246747|ensembl:ENSP00000436021 intact:EBI-3449344|uniprotkb:Q504R0|uniprotkb:B3KQJ5|ensembl:ENSP00000219204 psi-mi:arl2_human(display_long)|uniprotkb:ARL2(gene name)|psi-mi:ARL2(display_short) psi-mi:ar2bp_human(display_long)|uniprotkb:ARL2BP(gene name)|psi-mi:ARL2BP(display_short)|uniprotkb:BART(gene name synonym)|uniprotkb:BART1(gene name synonym)|uniprotkb:Binder of ARF2 protein 1(gene name synonym) psi-mi:"MI:0096"(pull down) Zhang et al. (2009) pubmed:19368893|doi:10.1016/j.str.2009.01.014|imex:IM-11776 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15769613|imex:IM-11776-3|dip:DIP-102551E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001186674.1|refseq:NP_001658.2|dip:DIP-47535N|ensembl:ENSG00000213465(gene)|ensembl:ENST00000246747(transcript)|ensembl:ENST00000529384(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005095"(GTPase inhibitor activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007021"(tubulin complex assembly)|go:"GO:0007098"(centrosome cycle)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019003"(GDP binding)|go:"GO:0031113"(regulation of microtubule polymerization)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0070830"(bicellular tight junction assembly)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|interpro:IPR044612|mint:P36404|rcsb pdb:3DOE|rcsb pdb:3DOF|reactome:R-HSA-389977|reactome:R-HSA-83936|reactome:R-HSA-9648002 refseq:NP_036238.1|dip:DIP-48323N|ensembl:ENSG00000102931(gene)|ensembl:ENST00000219204(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0007165"(signal transduction)|go:"GO:0030496"(midbody)|go:"GO:0030695"(GTPase regulator activity)|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0051457"(maintenance of protein location in nucleus)|interpro:IPR023379|interpro:IPR038849|interpro:IPR042541|rcsb pdb:2K9A|rcsb pdb:3DOE|rcsb pdb:3DOF|reactome:R-HSA-83936 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/06 2017/08/10 rogid:ArQxx65a8vITU2O0Kr0Qo0hqiqU9606 rogid:w0KrwWvWCYKloGK+8fPwAheajP09606 rigid:o0sgvz4UxjHJp1HAGGupm75EkdE false sufficient binding region:2-4|mutation disrupting interaction strength:3-3|mutation disrupting interaction:4-4|mutation disrupting interaction:6-6|mutation disrupting interaction:7-7|mutation disrupting interaction:50-50|mutation disrupting interaction:80-80|mutation disrupting interaction strength:3-3 mutation decreasing interaction:56-56|mutation decreasing interaction:57-57|mutation decreasing interaction:60-60|mutation decreasing interaction:109-109|mutation decreasing interaction:74-74|mutation decreasing interaction:110-110|mutation decreasing interaction:112-112|mutation decreasing interaction:115-115|glutathione s tranferase tag:n-n - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)