#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q99708 uniprotkb:Q90Z51 intact:EBI-745715|uniprotkb:A6NKN2|ensembl:ENSP00000323050|ensembl:ENSP00000382628|intact:EBI-1263531|uniprotkb:A8K8W6|uniprotkb:E7ETY1|uniprotkb:O75371|uniprotkb:Q8NHQ3 intact:EBI-15768175 psi-mi:ctip_human(display_long)|uniprotkb:RBBP8(gene name)|psi-mi:RBBP8(display_short)|uniprotkb:CTIP(gene name synonym)|uniprotkb:CtBP-interacting protein(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 8(gene name synonym)|uniprotkb:Retinoblastoma-interacting protein and myosin-like(gene name synonym)|uniprotkb:Sporulation in the absence of SPO11 protein 2 homolog(gene name synonym) psi-mi:q90z51_chick(display_long)|uniprotkb:BRCA1(gene name)|psi-mi:BRCA1(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Yun et al. (2009) pubmed:19357644|doi:10.1038/nature07955|imex:IM-17837 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15768204|imex:IM-17837-1|dip:DIP-189259E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011524434.1|ensembl:ENSG00000101773(gene)|ensembl:ENST00000327155(transcript)|ensembl:ENST00000399722(transcript)|go:"GO:0000014"(single-stranded DNA endodeoxyribonuclease activity)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000403"(Y-form DNA binding)|go:"GO:0000406"(double-strand/single-strand DNA junction binding)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010792"(DNA double-strand break processing involved in repair via single-strand annealing)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0032355"(response to estradiol)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070336"(flap-structured DNA binding)|interpro:IPR013882(DNA repair protein Sae2)|interpro:IPR019518|interpro:IPR033316|interpro:IPR033594|mint:Q99708|rcsb pdb:2L4Z|rcsb pdb:4D2H|rcsb pdb:7BGF|reactome:R-HSA-5685938|reactome:R-HSA-5685939|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6804756|reactome:R-HSA-69473|reactome:R-HSA-8953750|reactome:R-HSA-912446|refseq:NP_002885.1|refseq:NP_976036.1|refseq:NP_976037.1|refseq:XP_006722582.1|refseq:XP_006722583.1|refseq:XP_006722584.1|dip:DIP-24244N go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003677"(DNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0006301"(postreplication repair)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0045717"(negative regulation of fatty acid biosynthetic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001357(BRCT)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011364(BRCA1)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018957|interpro:IPR025994|interpro:IPR031099|interpro:IPR036420|refseq:NP_989500.1|reactome:R-GGA-265976|reactome:R-GGA-351433|dip:DIP-59755N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") - 2017/08/06 2017/08/10 rogid:4oYHOQGiavaE9TTzRbHyOZtL28E9606 rogid:0TymVvm+kwodvBQAwLAbVe0IPIo9031 rigid:UOG52VGihKIrn6nnlBeTG1nSw9w false mutation disrupting interaction:327-327 - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)