#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q96G30 uniprotkb:Q01718 intact:EBI-9537218|uniprotkb:A8K9M1|uniprotkb:Q8IXM9|uniprotkb:Q8N2D1|ensembl:ENSP00000257776 intact:EBI-9537171|uniprotkb:A8K016|uniprotkb:Q3MI45|uniprotkb:Q504X6|ensembl:ENSP00000333821 psi-mi:mrap2_human(display_long)|uniprotkb:MRAP2(gene name)|psi-mi:MRAP2(display_short)|uniprotkb:C6orf117(gene name synonym) psi-mi:acthr_human(display_long)|uniprotkb:MC2R(gene name)|psi-mi:MC2R(display_short)|uniprotkb:ACTHR(gene name synonym)|uniprotkb:Adrenocorticotropin receptor(gene name synonym)|uniprotkb:Melanocortin receptor 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chan et al. (2009) pubmed:19329486|doi:10.1073/pnas.0809918106|imex:IM-14700 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15765930|imex:IM-14700-1|dip:DIP-103728E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_016865709.1|refseq:NP_001333470.1|refseq:NP_001333471.1|refseq:NP_001333473.1|refseq:NP_612418.2|dip:DIP-48793N|ensembl:ENSG00000135324(gene)|ensembl:ENST00000257776(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006112"(energy reserve metabolic process)|go:"GO:0007631"(feeding behavior)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030545"(signaling receptor regulator activity)|go:"GO:0031780"(corticotropin hormone receptor binding)|go:"GO:0031781"(type 3 melanocortin receptor binding)|go:"GO:0031782"(type 4 melanocortin receptor binding)|go:"GO:0031783"(type 5 melanocortin receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0070996"(type 1 melanocortin receptor binding)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0097009"(energy homeostasis)|go:"GO:0106070"(regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0106071"(positive regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0106072"(negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|interpro:IPR028111 refseq:XP_016881270.1|refseq:NP_001278840.1|refseq:NP_000520.1|dip:DIP-29949N|ensembl:ENSG00000185231(gene)|ensembl:ENST00000327606(transcript)|go:"GO:0001890"(placenta development)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004977"(melanocortin receptor activity)|go:"GO:0004978"(corticotropin receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0019222"(regulation of metabolic process)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001168("Adrenocorticotrophin (ACTH) receptor")|interpro:IPR001671(Melanocortin/ACTH receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-HSA-375276|reactome:R-HSA-418555|reactome:R-HSA-5579031|reactome:R-HSA-9660821 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr)|taxid:10029("Cricetulus griseus (Chinese hamster)") - 2017/08/06 2017/08/10 rogid:EjEqEJckYyHeCg3ANFDSFlfd85E9606 rogid:8ws6S3uX+iCrWkXmZ05MErv+FSI9606 rigid:6HZe5i1hOB/17ZC4oFqx5MKRGs4 false myc tag:n-n ha tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q8TCY5 uniprotkb:Q01726 intact:EBI-9538727|uniprotkb:Q5EBR3|uniprotkb:Q8TDB7|uniprotkb:Q8WXC1|uniprotkb:Q8WXC2|ensembl:ENSP00000306697|ensembl:ENSP00000382684 intact:EBI-9538513|uniprotkb:Q66K38|uniprotkb:Q6UR93|uniprotkb:Q8WWX6|uniprotkb:Q8WWX7|uniprotkb:Q96I33|uniprotkb:Q96RU4|uniprotkb:Q9UBF7|uniprotkb:Q9UN58|uniprotkb:Q9UN59|uniprotkb:Q9UN60|uniprotkb:Q9UN61|uniprotkb:Q9UN62|ensembl:ENSP00000451605|ensembl:ENSP00000492011 psi-mi:mrap_human(display_long)|uniprotkb:MRAP(gene name)|psi-mi:MRAP(display_short)|uniprotkb:B27(gene name synonym)|uniprotkb:C21orf61(gene name synonym)|uniprotkb:FALP(gene name synonym)|uniprotkb:Fat cell-specific low molecular weight protein(gene name synonym)|uniprotkb:Fat tissue-specific low MW protein(gene name synonym) psi-mi:mshr_human(display_long)|uniprotkb:MC1R(gene name)|psi-mi:MC1R(display_short)|uniprotkb:MSHR(gene name synonym)|uniprotkb:Melanocortin receptor 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chan et al. (2009) pubmed:19329486|doi:10.1073/pnas.0809918106|imex:IM-14700 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15766056|imex:IM-14700-7|dip:DIP-103733E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_016883896.1|refseq:NP_001272323.1|refseq:NP_848932.1|refseq:NP_996781.1|refseq:XP_006724091.1|dip:DIP-29948N|ensembl:ENSG00000170262(gene)|ensembl:ENST00000303645(transcript)|ensembl:ENST00000399784(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030545"(signaling receptor regulator activity)|go:"GO:0031780"(corticotropin hormone receptor binding)|go:"GO:0031781"(type 3 melanocortin receptor binding)|go:"GO:0031782"(type 4 melanocortin receptor binding)|go:"GO:0031783"(type 5 melanocortin receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0070996"(type 1 melanocortin receptor binding)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0106070"(regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0106072"(negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|interpro:IPR028111|go:"GO:0106071"(positive regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway) refseq:NP_002377.4|dip:DIP-48789N|ensembl:ENSG00000258839(gene)|ensembl:ENST00000555147(transcript)|ensembl:ENST00000639847(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004977"(melanocortin receptor activity)|go:"GO:0004980"(melanocyte-stimulating hormone receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008528"(G protein-coupled peptide receptor activity)|go:"GO:0009650"(UV protection)|go:"GO:0010739"(positive regulation of protein kinase A signaling)|go:"GO:0019222"(regulation of metabolic process)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042438"(melanin biosynthetic process)|go:"GO:0043473"(pigmentation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0070914"(UV-damage excision repair)|go:"GO:0090037"(positive regulation of protein kinase C signaling)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000761(Melanocyte-stimulating hormone receptor)|interpro:IPR001671(Melanocortin/ACTH receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-HSA-375276|reactome:R-HSA-418555|reactome:R-HSA-9660821 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr)|taxid:10029("Cricetulus griseus (Chinese hamster)") - 2017/08/06 2017/08/10 rogid:Jx6MGR2o7drwH3LVeo3hbAMW72I9606 rogid:bRaeDGsvigniM0X4LiqUDMrsmwg9606 rigid:qL9cDywoGHPDio9ReyzeVqXt5bs false flag tag:c-c ha tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q01726 uniprotkb:Q96G30 intact:EBI-9538513|uniprotkb:Q66K38|uniprotkb:Q6UR93|uniprotkb:Q8WWX6|uniprotkb:Q8WWX7|uniprotkb:Q96I33|uniprotkb:Q96RU4|uniprotkb:Q9UBF7|uniprotkb:Q9UN58|uniprotkb:Q9UN59|uniprotkb:Q9UN60|uniprotkb:Q9UN61|uniprotkb:Q9UN62|ensembl:ENSP00000451605|ensembl:ENSP00000492011 intact:EBI-9537218|uniprotkb:A8K9M1|uniprotkb:Q8IXM9|uniprotkb:Q8N2D1|ensembl:ENSP00000257776 psi-mi:mshr_human(display_long)|uniprotkb:MC1R(gene name)|psi-mi:MC1R(display_short)|uniprotkb:MSHR(gene name synonym)|uniprotkb:Melanocortin receptor 1(gene name synonym) psi-mi:mrap2_human(display_long)|uniprotkb:MRAP2(gene name)|psi-mi:MRAP2(display_short)|uniprotkb:C6orf117(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chan et al. (2009) pubmed:19329486|doi:10.1073/pnas.0809918106|imex:IM-14700 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15766035|imex:IM-14700-6|dip:DIP-103729E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002377.4|dip:DIP-48789N|ensembl:ENSG00000258839(gene)|ensembl:ENST00000555147(transcript)|ensembl:ENST00000639847(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004977"(melanocortin receptor activity)|go:"GO:0004980"(melanocyte-stimulating hormone receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008528"(G protein-coupled peptide receptor activity)|go:"GO:0009650"(UV protection)|go:"GO:0010739"(positive regulation of protein kinase A signaling)|go:"GO:0019222"(regulation of metabolic process)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042438"(melanin biosynthetic process)|go:"GO:0043473"(pigmentation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0070914"(UV-damage excision repair)|go:"GO:0090037"(positive regulation of protein kinase C signaling)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000761(Melanocyte-stimulating hormone receptor)|interpro:IPR001671(Melanocortin/ACTH receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-HSA-375276|reactome:R-HSA-418555|reactome:R-HSA-9660821 refseq:XP_016865709.1|refseq:NP_001333470.1|refseq:NP_001333471.1|refseq:NP_001333473.1|refseq:NP_612418.2|dip:DIP-48793N|ensembl:ENSG00000135324(gene)|ensembl:ENST00000257776(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006112"(energy reserve metabolic process)|go:"GO:0007631"(feeding behavior)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030545"(signaling receptor regulator activity)|go:"GO:0031780"(corticotropin hormone receptor binding)|go:"GO:0031781"(type 3 melanocortin receptor binding)|go:"GO:0031782"(type 4 melanocortin receptor binding)|go:"GO:0031783"(type 5 melanocortin receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0070996"(type 1 melanocortin receptor binding)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0097009"(energy homeostasis)|go:"GO:0106070"(regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0106071"(positive regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0106072"(negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|interpro:IPR028111 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr)|taxid:10029("Cricetulus griseus (Chinese hamster)") - 2017/08/06 2017/08/10 rogid:bRaeDGsvigniM0X4LiqUDMrsmwg9606 rogid:EjEqEJckYyHeCg3ANFDSFlfd85E9606 rigid:kcrt+/j4pHz+UE+yfPzPKjy98Mg false ha tag:n-n myc tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8TCY5 uniprotkb:Q96G30 intact:EBI-9538727|uniprotkb:Q5EBR3|uniprotkb:Q8TDB7|uniprotkb:Q8WXC1|uniprotkb:Q8WXC2|ensembl:ENSP00000306697|ensembl:ENSP00000382684 intact:EBI-9537218|uniprotkb:A8K9M1|uniprotkb:Q8IXM9|uniprotkb:Q8N2D1|ensembl:ENSP00000257776 psi-mi:mrap_human(display_long)|uniprotkb:MRAP(gene name)|psi-mi:MRAP(display_short)|uniprotkb:B27(gene name synonym)|uniprotkb:C21orf61(gene name synonym)|uniprotkb:FALP(gene name synonym)|uniprotkb:Fat cell-specific low molecular weight protein(gene name synonym)|uniprotkb:Fat tissue-specific low MW protein(gene name synonym) psi-mi:mrap2_human(display_long)|uniprotkb:MRAP2(gene name)|psi-mi:MRAP2(display_short)|uniprotkb:C6orf117(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chan et al. (2009) pubmed:19329486|doi:10.1073/pnas.0809918106|imex:IM-14700 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15766014|imex:IM-14700-5|dip:DIP-103738E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_016883896.1|refseq:NP_001272323.1|refseq:NP_848932.1|refseq:NP_996781.1|refseq:XP_006724091.1|dip:DIP-29948N|ensembl:ENSG00000170262(gene)|ensembl:ENST00000303645(transcript)|ensembl:ENST00000399784(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030545"(signaling receptor regulator activity)|go:"GO:0031780"(corticotropin hormone receptor binding)|go:"GO:0031781"(type 3 melanocortin receptor binding)|go:"GO:0031782"(type 4 melanocortin receptor binding)|go:"GO:0031783"(type 5 melanocortin receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0070996"(type 1 melanocortin receptor binding)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0106070"(regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0106072"(negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|interpro:IPR028111|go:"GO:0106071"(positive regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway) refseq:XP_016865709.1|refseq:NP_001333470.1|refseq:NP_001333471.1|refseq:NP_001333473.1|refseq:NP_612418.2|dip:DIP-48793N|ensembl:ENSG00000135324(gene)|ensembl:ENST00000257776(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006112"(energy reserve metabolic process)|go:"GO:0007631"(feeding behavior)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030545"(signaling receptor regulator activity)|go:"GO:0031780"(corticotropin hormone receptor binding)|go:"GO:0031781"(type 3 melanocortin receptor binding)|go:"GO:0031782"(type 4 melanocortin receptor binding)|go:"GO:0031783"(type 5 melanocortin receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0070996"(type 1 melanocortin receptor binding)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0097009"(energy homeostasis)|go:"GO:0106070"(regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0106071"(positive regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0106072"(negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|interpro:IPR028111 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr)|taxid:10029("Cricetulus griseus (Chinese hamster)") - 2017/08/06 2017/08/10 rogid:Jx6MGR2o7drwH3LVeo3hbAMW72I9606 rogid:EjEqEJckYyHeCg3ANFDSFlfd85E9606 rigid:xXxieZTO35aWb87/6mNpRpTWDPY false flag tag:c-c myc tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P33032 uniprotkb:Q8TCY5 intact:EBI-9538507|uniprotkb:B0YJ34|uniprotkb:Q502V1|ensembl:ENSP00000318077|ensembl:ENSP00000468086 intact:EBI-9538727|uniprotkb:Q5EBR3|uniprotkb:Q8TDB7|uniprotkb:Q8WXC1|uniprotkb:Q8WXC2|ensembl:ENSP00000306697|ensembl:ENSP00000382684 psi-mi:mc5r_human(display_long)|uniprotkb:MC5R(gene name)|psi-mi:MC5R(display_short)|uniprotkb:MC-2(gene name synonym) psi-mi:mrap_human(display_long)|uniprotkb:MRAP(gene name)|psi-mi:MRAP(display_short)|uniprotkb:B27(gene name synonym)|uniprotkb:C21orf61(gene name synonym)|uniprotkb:FALP(gene name synonym)|uniprotkb:Fat cell-specific low molecular weight protein(gene name synonym)|uniprotkb:Fat tissue-specific low MW protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chan et al. (2009) pubmed:19329486|doi:10.1073/pnas.0809918106|imex:IM-14700 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15765993|imex:IM-14700-4|dip:DIP-103736E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005904.1|dip:DIP-48792N|ensembl:ENSG00000176136(gene)|ensembl:ENST00000324750(transcript)|ensembl:ENST00000589410(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004977"(melanocortin receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0019222"(regulation of metabolic process)|go:"GO:0042562"(hormone binding)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000621(Melanocortin 5 receptor)|interpro:IPR001671(Melanocortin/ACTH receptor)|interpro:IPR001908(Melanocortin receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-HSA-375276|reactome:R-HSA-418555|reactome:R-HSA-9660821 refseq:XP_016883896.1|refseq:NP_001272323.1|refseq:NP_848932.1|refseq:NP_996781.1|refseq:XP_006724091.1|dip:DIP-29948N|ensembl:ENSG00000170262(gene)|ensembl:ENST00000303645(transcript)|ensembl:ENST00000399784(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030545"(signaling receptor regulator activity)|go:"GO:0031780"(corticotropin hormone receptor binding)|go:"GO:0031781"(type 3 melanocortin receptor binding)|go:"GO:0031782"(type 4 melanocortin receptor binding)|go:"GO:0031783"(type 5 melanocortin receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0070996"(type 1 melanocortin receptor binding)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0106070"(regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0106072"(negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|interpro:IPR028111|go:"GO:0106071"(positive regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr)|taxid:10029("Cricetulus griseus (Chinese hamster)") - 2017/08/06 2017/08/10 rogid:uCeQ+zh9889q7riyd00rSGLwXKA9606 rogid:Jx6MGR2o7drwH3LVeo3hbAMW72I9606 rigid:kjjS++V1aJDekbNtiZWu1fsaOEE false ha tag:n-n flag tag:c-c - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P41968 uniprotkb:Q8TCY5 intact:EBI-9538510|uniprotkb:Q4KN27|uniprotkb:Q9H517|ensembl:ENSP00000243911 intact:EBI-9538727|uniprotkb:Q5EBR3|uniprotkb:Q8TDB7|uniprotkb:Q8WXC1|uniprotkb:Q8WXC2|ensembl:ENSP00000306697|ensembl:ENSP00000382684 psi-mi:mc3r_human(display_long)|uniprotkb:MC3R(gene name)|psi-mi:MC3R(display_short) psi-mi:mrap_human(display_long)|uniprotkb:MRAP(gene name)|psi-mi:MRAP(display_short)|uniprotkb:B27(gene name synonym)|uniprotkb:C21orf61(gene name synonym)|uniprotkb:FALP(gene name synonym)|uniprotkb:Fat cell-specific low molecular weight protein(gene name synonym)|uniprotkb:Fat tissue-specific low MW protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chan et al. (2009) pubmed:19329486|doi:10.1073/pnas.0809918106|imex:IM-14700 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15765972|imex:IM-14700-3|dip:DIP-103734E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_063941.3|dip:DIP-48790N|ensembl:ENSG00000124089(gene)|ensembl:ENST00000243911(transcript)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004977"(melanocortin receptor activity)|go:"GO:0004980"(melanocyte-stimulating hormone receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0017046"(peptide hormone binding)|go:"GO:0019222"(regulation of metabolic process)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042309"(homoiothermy)|go:"GO:0042923"(neuropeptide binding)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0055078"(sodium ion homeostasis)|go:"GO:0060259"(regulation of feeding behavior)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001671(Melanocortin/ACTH receptor)|interpro:IPR001908(Melanocortin receptor)|interpro:IPR002122(Melanocortin 3 receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-HSA-375276|reactome:R-HSA-418555|reactome:R-HSA-9660821 refseq:XP_016883896.1|refseq:NP_001272323.1|refseq:NP_848932.1|refseq:NP_996781.1|refseq:XP_006724091.1|dip:DIP-29948N|ensembl:ENSG00000170262(gene)|ensembl:ENST00000303645(transcript)|ensembl:ENST00000399784(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030545"(signaling receptor regulator activity)|go:"GO:0031780"(corticotropin hormone receptor binding)|go:"GO:0031781"(type 3 melanocortin receptor binding)|go:"GO:0031782"(type 4 melanocortin receptor binding)|go:"GO:0031783"(type 5 melanocortin receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0070996"(type 1 melanocortin receptor binding)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0106070"(regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0106072"(negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|interpro:IPR028111|go:"GO:0106071"(positive regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr)|taxid:10029("Cricetulus griseus (Chinese hamster)") - 2017/08/06 2017/08/10 rogid:SPh+bWidDfIyPMfxKka6vVQ1q3U9606 rogid:Jx6MGR2o7drwH3LVeo3hbAMW72I9606 rigid:E45b8WkwcXtLFN5S1rwq9D6SLuE false ha tag:n-n flag tag:c-c - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P33032 uniprotkb:Q96G30 intact:EBI-9538507|uniprotkb:B0YJ34|uniprotkb:Q502V1|ensembl:ENSP00000318077|ensembl:ENSP00000468086 intact:EBI-9537218|uniprotkb:A8K9M1|uniprotkb:Q8IXM9|uniprotkb:Q8N2D1|ensembl:ENSP00000257776 psi-mi:mc5r_human(display_long)|uniprotkb:MC5R(gene name)|psi-mi:MC5R(display_short)|uniprotkb:MC-2(gene name synonym) psi-mi:mrap2_human(display_long)|uniprotkb:MRAP2(gene name)|psi-mi:MRAP2(display_short)|uniprotkb:C6orf117(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chan et al. (2009) pubmed:19329486|doi:10.1073/pnas.0809918106|imex:IM-14700 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15765951|imex:IM-14700-2|dip:DIP-103732E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005904.1|dip:DIP-48792N|ensembl:ENSG00000176136(gene)|ensembl:ENST00000324750(transcript)|ensembl:ENST00000589410(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004977"(melanocortin receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0019222"(regulation of metabolic process)|go:"GO:0042562"(hormone binding)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000621(Melanocortin 5 receptor)|interpro:IPR001671(Melanocortin/ACTH receptor)|interpro:IPR001908(Melanocortin receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-HSA-375276|reactome:R-HSA-418555|reactome:R-HSA-9660821 refseq:XP_016865709.1|refseq:NP_001333470.1|refseq:NP_001333471.1|refseq:NP_001333473.1|refseq:NP_612418.2|dip:DIP-48793N|ensembl:ENSG00000135324(gene)|ensembl:ENST00000257776(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006112"(energy reserve metabolic process)|go:"GO:0007631"(feeding behavior)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030545"(signaling receptor regulator activity)|go:"GO:0031780"(corticotropin hormone receptor binding)|go:"GO:0031781"(type 3 melanocortin receptor binding)|go:"GO:0031782"(type 4 melanocortin receptor binding)|go:"GO:0031783"(type 5 melanocortin receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0070996"(type 1 melanocortin receptor binding)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0097009"(energy homeostasis)|go:"GO:0106070"(regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0106071"(positive regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0106072"(negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|interpro:IPR028111 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr)|taxid:10029("Cricetulus griseus (Chinese hamster)") - 2017/08/06 2017/08/10 rogid:uCeQ+zh9889q7riyd00rSGLwXKA9606 rogid:EjEqEJckYyHeCg3ANFDSFlfd85E9606 rigid:bZ4XUU2YMlJpUbW8wDXARnBqg5s false ha tag:n-n myc tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32245 uniprotkb:Q8TCY5 intact:EBI-3910694|uniprotkb:B2RAC3|uniprotkb:Q16317|uniprotkb:Q3MIJ6|ensembl:ENSP00000299766 intact:EBI-9538727|uniprotkb:Q5EBR3|uniprotkb:Q8TDB7|uniprotkb:Q8WXC1|uniprotkb:Q8WXC2|ensembl:ENSP00000306697|ensembl:ENSP00000382684 psi-mi:mc4r_human(display_long)|uniprotkb:MC4R(gene name)|psi-mi:MC4R(display_short) psi-mi:mrap_human(display_long)|uniprotkb:MRAP(gene name)|psi-mi:MRAP(display_short)|uniprotkb:B27(gene name synonym)|uniprotkb:C21orf61(gene name synonym)|uniprotkb:FALP(gene name synonym)|uniprotkb:Fat cell-specific low molecular weight protein(gene name synonym)|uniprotkb:Fat tissue-specific low MW protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chan et al. (2009) pubmed:19329486|doi:10.1073/pnas.0809918106|imex:IM-14700 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15766077|imex:IM-14700-8|dip:DIP-103735E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005903.2|ensembl:ENSG00000166603(gene)|ensembl:ENST00000299766(transcript)|go:"GO:0002024"(diet induced thermogenesis)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004977"(melanocortin receptor activity)|go:"GO:0004980"(melanocyte-stimulating hormone receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006112"(energy reserve metabolic process)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007631"(feeding behavior)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017046"(peptide hormone binding)|go:"GO:0019222"(regulation of metabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042923"(neuropeptide binding)|go:"GO:0045780"(positive regulation of bone resorption)|go:"GO:2000252"(negative regulation of feeding behavior)|go:"GO:0005886"(plasma membrane)|go:"GO:2000821"(regulation of grooming behavior)|interpro:IPR000155(Melanocortin 4 receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001671(Melanocortin/ACTH receptor)|interpro:IPR001908(Melanocortin receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2IQP|rcsb pdb:2IQR|rcsb pdb:2IQS|rcsb pdb:2IQU|rcsb pdb:2IQV|rcsb pdb:2IQW|rcsb pdb:6W25|rcsb pdb:7AUE|reactome:R-HSA-375276|reactome:R-HSA-418555|reactome:R-HSA-9660821|dip:DIP-48791N refseq:XP_016883896.1|refseq:NP_001272323.1|refseq:NP_848932.1|refseq:NP_996781.1|refseq:XP_006724091.1|dip:DIP-29948N|ensembl:ENSG00000170262(gene)|ensembl:ENST00000303645(transcript)|ensembl:ENST00000399784(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030545"(signaling receptor regulator activity)|go:"GO:0031780"(corticotropin hormone receptor binding)|go:"GO:0031781"(type 3 melanocortin receptor binding)|go:"GO:0031782"(type 4 melanocortin receptor binding)|go:"GO:0031783"(type 5 melanocortin receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0070996"(type 1 melanocortin receptor binding)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0106070"(regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0106072"(negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|interpro:IPR028111|go:"GO:0106071"(positive regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr)|taxid:10029("Cricetulus griseus (Chinese hamster)") - 2017/08/06 2017/08/10 rogid:Ugo3YVG2pY/auS33oQ3tB1jZK9w9606 rogid:Jx6MGR2o7drwH3LVeo3hbAMW72I9606 rigid:V/DORebskX1/jI6S94A6G1aDH/w false ha tag:n-n flag tag:c-c - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P41968 uniprotkb:Q96G30 intact:EBI-9538510|uniprotkb:Q4KN27|uniprotkb:Q9H517|ensembl:ENSP00000243911 intact:EBI-9537218|uniprotkb:A8K9M1|uniprotkb:Q8IXM9|uniprotkb:Q8N2D1|ensembl:ENSP00000257776 psi-mi:mc3r_human(display_long)|uniprotkb:MC3R(gene name)|psi-mi:MC3R(display_short) psi-mi:mrap2_human(display_long)|uniprotkb:MRAP2(gene name)|psi-mi:MRAP2(display_short)|uniprotkb:C6orf117(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chan et al. (2009) pubmed:19329486|doi:10.1073/pnas.0809918106|imex:IM-14700 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15766119|imex:IM-14700-10|dip:DIP-103730E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_063941.3|dip:DIP-48790N|ensembl:ENSG00000124089(gene)|ensembl:ENST00000243911(transcript)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004977"(melanocortin receptor activity)|go:"GO:0004980"(melanocyte-stimulating hormone receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0017046"(peptide hormone binding)|go:"GO:0019222"(regulation of metabolic process)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042309"(homoiothermy)|go:"GO:0042923"(neuropeptide binding)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0055078"(sodium ion homeostasis)|go:"GO:0060259"(regulation of feeding behavior)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001671(Melanocortin/ACTH receptor)|interpro:IPR001908(Melanocortin receptor)|interpro:IPR002122(Melanocortin 3 receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-HSA-375276|reactome:R-HSA-418555|reactome:R-HSA-9660821 refseq:XP_016865709.1|refseq:NP_001333470.1|refseq:NP_001333471.1|refseq:NP_001333473.1|refseq:NP_612418.2|dip:DIP-48793N|ensembl:ENSG00000135324(gene)|ensembl:ENST00000257776(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006112"(energy reserve metabolic process)|go:"GO:0007631"(feeding behavior)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030545"(signaling receptor regulator activity)|go:"GO:0031780"(corticotropin hormone receptor binding)|go:"GO:0031781"(type 3 melanocortin receptor binding)|go:"GO:0031782"(type 4 melanocortin receptor binding)|go:"GO:0031783"(type 5 melanocortin receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0070996"(type 1 melanocortin receptor binding)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0097009"(energy homeostasis)|go:"GO:0106070"(regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0106071"(positive regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0106072"(negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|interpro:IPR028111 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr)|taxid:10029("Cricetulus griseus (Chinese hamster)") - 2017/08/06 2017/08/10 rogid:SPh+bWidDfIyPMfxKka6vVQ1q3U9606 rogid:EjEqEJckYyHeCg3ANFDSFlfd85E9606 rigid:BbNO3F5KtAUEU+xGxe3YgmUfVHk false ha tag:n-n myc tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8TCY5 uniprotkb:Q01726 intact:EBI-9538727|uniprotkb:Q5EBR3|uniprotkb:Q8TDB7|uniprotkb:Q8WXC1|uniprotkb:Q8WXC2|ensembl:ENSP00000306697|ensembl:ENSP00000382684 intact:EBI-9538513|uniprotkb:Q66K38|uniprotkb:Q6UR93|uniprotkb:Q8WWX6|uniprotkb:Q8WWX7|uniprotkb:Q96I33|uniprotkb:Q96RU4|uniprotkb:Q9UBF7|uniprotkb:Q9UN58|uniprotkb:Q9UN59|uniprotkb:Q9UN60|uniprotkb:Q9UN61|uniprotkb:Q9UN62|ensembl:ENSP00000451605|ensembl:ENSP00000492011 psi-mi:mrap_human(display_long)|uniprotkb:MRAP(gene name)|psi-mi:MRAP(display_short)|uniprotkb:B27(gene name synonym)|uniprotkb:C21orf61(gene name synonym)|uniprotkb:FALP(gene name synonym)|uniprotkb:Fat cell-specific low molecular weight protein(gene name synonym)|uniprotkb:Fat tissue-specific low MW protein(gene name synonym) psi-mi:mshr_human(display_long)|uniprotkb:MC1R(gene name)|psi-mi:MC1R(display_short)|uniprotkb:MSHR(gene name synonym)|uniprotkb:Melanocortin receptor 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chan et al. (2009) pubmed:19329486|doi:10.1073/pnas.0809918106|imex:IM-14700 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15766140|imex:IM-14700-11|dip:DIP-103733E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_016883896.1|refseq:NP_001272323.1|refseq:NP_848932.1|refseq:NP_996781.1|refseq:XP_006724091.1|dip:DIP-29948N|ensembl:ENSG00000170262(gene)|ensembl:ENST00000303645(transcript)|ensembl:ENST00000399784(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030545"(signaling receptor regulator activity)|go:"GO:0031780"(corticotropin hormone receptor binding)|go:"GO:0031781"(type 3 melanocortin receptor binding)|go:"GO:0031782"(type 4 melanocortin receptor binding)|go:"GO:0031783"(type 5 melanocortin receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0070996"(type 1 melanocortin receptor binding)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0106070"(regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0106072"(negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|interpro:IPR028111|go:"GO:0106071"(positive regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway) refseq:NP_002377.4|dip:DIP-48789N|ensembl:ENSG00000258839(gene)|ensembl:ENST00000555147(transcript)|ensembl:ENST00000639847(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004977"(melanocortin receptor activity)|go:"GO:0004980"(melanocyte-stimulating hormone receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008528"(G protein-coupled peptide receptor activity)|go:"GO:0009650"(UV protection)|go:"GO:0010739"(positive regulation of protein kinase A signaling)|go:"GO:0019222"(regulation of metabolic process)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042438"(melanin biosynthetic process)|go:"GO:0043473"(pigmentation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0070914"(UV-damage excision repair)|go:"GO:0090037"(positive regulation of protein kinase C signaling)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000761(Melanocyte-stimulating hormone receptor)|interpro:IPR001671(Melanocortin/ACTH receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-HSA-375276|reactome:R-HSA-418555|reactome:R-HSA-9660821 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr)|taxid:10029("Cricetulus griseus (Chinese hamster)") - 2017/08/06 2017/08/10 rogid:Jx6MGR2o7drwH3LVeo3hbAMW72I9606 rogid:bRaeDGsvigniM0X4LiqUDMrsmwg9606 rigid:qL9cDywoGHPDio9ReyzeVqXt5bs false flag tag:c-c ha tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32245 uniprotkb:Q8TCY5 intact:EBI-3910694|uniprotkb:B2RAC3|uniprotkb:Q16317|uniprotkb:Q3MIJ6|ensembl:ENSP00000299766 intact:EBI-9538727|uniprotkb:Q5EBR3|uniprotkb:Q8TDB7|uniprotkb:Q8WXC1|uniprotkb:Q8WXC2|ensembl:ENSP00000306697|ensembl:ENSP00000382684 psi-mi:mc4r_human(display_long)|uniprotkb:MC4R(gene name)|psi-mi:MC4R(display_short) psi-mi:mrap_human(display_long)|uniprotkb:MRAP(gene name)|psi-mi:MRAP(display_short)|uniprotkb:B27(gene name synonym)|uniprotkb:C21orf61(gene name synonym)|uniprotkb:FALP(gene name synonym)|uniprotkb:Fat cell-specific low molecular weight protein(gene name synonym)|uniprotkb:Fat tissue-specific low MW protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chan et al. (2009) pubmed:19329486|doi:10.1073/pnas.0809918106|imex:IM-14700 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15766161|imex:IM-14700-12|dip:DIP-103735E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005903.2|ensembl:ENSG00000166603(gene)|ensembl:ENST00000299766(transcript)|go:"GO:0002024"(diet induced thermogenesis)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004977"(melanocortin receptor activity)|go:"GO:0004980"(melanocyte-stimulating hormone receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006112"(energy reserve metabolic process)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007631"(feeding behavior)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017046"(peptide hormone binding)|go:"GO:0019222"(regulation of metabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042923"(neuropeptide binding)|go:"GO:0045780"(positive regulation of bone resorption)|go:"GO:2000252"(negative regulation of feeding behavior)|go:"GO:0005886"(plasma membrane)|go:"GO:2000821"(regulation of grooming behavior)|interpro:IPR000155(Melanocortin 4 receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001671(Melanocortin/ACTH receptor)|interpro:IPR001908(Melanocortin receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2IQP|rcsb pdb:2IQR|rcsb pdb:2IQS|rcsb pdb:2IQU|rcsb pdb:2IQV|rcsb pdb:2IQW|rcsb pdb:6W25|rcsb pdb:7AUE|reactome:R-HSA-375276|reactome:R-HSA-418555|reactome:R-HSA-9660821|dip:DIP-48791N refseq:XP_016883896.1|refseq:NP_001272323.1|refseq:NP_848932.1|refseq:NP_996781.1|refseq:XP_006724091.1|dip:DIP-29948N|ensembl:ENSG00000170262(gene)|ensembl:ENST00000303645(transcript)|ensembl:ENST00000399784(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030545"(signaling receptor regulator activity)|go:"GO:0031780"(corticotropin hormone receptor binding)|go:"GO:0031781"(type 3 melanocortin receptor binding)|go:"GO:0031782"(type 4 melanocortin receptor binding)|go:"GO:0031783"(type 5 melanocortin receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0070996"(type 1 melanocortin receptor binding)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0106070"(regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0106072"(negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|interpro:IPR028111|go:"GO:0106071"(positive regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr)|taxid:10029("Cricetulus griseus (Chinese hamster)") - 2017/08/06 2017/08/10 rogid:Ugo3YVG2pY/auS33oQ3tB1jZK9w9606 rogid:Jx6MGR2o7drwH3LVeo3hbAMW72I9606 rigid:V/DORebskX1/jI6S94A6G1aDH/w false ha tag:n-n flag tag:c-c - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q96G30 uniprotkb:Q96G30 intact:EBI-9537218|uniprotkb:A8K9M1|uniprotkb:Q8IXM9|uniprotkb:Q8N2D1|ensembl:ENSP00000257776 intact:EBI-9537218|uniprotkb:A8K9M1|uniprotkb:Q8IXM9|uniprotkb:Q8N2D1|ensembl:ENSP00000257776 psi-mi:mrap2_human(display_long)|uniprotkb:MRAP2(gene name)|psi-mi:MRAP2(display_short)|uniprotkb:C6orf117(gene name synonym) psi-mi:mrap2_human(display_long)|uniprotkb:MRAP2(gene name)|psi-mi:MRAP2(display_short)|uniprotkb:C6orf117(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chan et al. (2009) pubmed:19329486|doi:10.1073/pnas.0809918106|imex:IM-14700 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15766098|imex:IM-14700-9|dip:DIP-103737E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_016865709.1|refseq:NP_001333470.1|refseq:NP_001333471.1|refseq:NP_001333473.1|refseq:NP_612418.2|dip:DIP-48793N|ensembl:ENSG00000135324(gene)|ensembl:ENST00000257776(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006112"(energy reserve metabolic process)|go:"GO:0007631"(feeding behavior)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030545"(signaling receptor regulator activity)|go:"GO:0031780"(corticotropin hormone receptor binding)|go:"GO:0031781"(type 3 melanocortin receptor binding)|go:"GO:0031782"(type 4 melanocortin receptor binding)|go:"GO:0031783"(type 5 melanocortin receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0070996"(type 1 melanocortin receptor binding)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0097009"(energy homeostasis)|go:"GO:0106070"(regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0106071"(positive regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0106072"(negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|interpro:IPR028111 refseq:XP_016865709.1|refseq:NP_001333470.1|refseq:NP_001333471.1|refseq:NP_001333473.1|refseq:NP_612418.2|dip:DIP-48793N|ensembl:ENSG00000135324(gene)|ensembl:ENST00000257776(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006112"(energy reserve metabolic process)|go:"GO:0007631"(feeding behavior)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030545"(signaling receptor regulator activity)|go:"GO:0031780"(corticotropin hormone receptor binding)|go:"GO:0031781"(type 3 melanocortin receptor binding)|go:"GO:0031782"(type 4 melanocortin receptor binding)|go:"GO:0031783"(type 5 melanocortin receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0070996"(type 1 melanocortin receptor binding)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0097009"(energy homeostasis)|go:"GO:0106070"(regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0106071"(positive regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0106072"(negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|interpro:IPR028111 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr)|taxid:10029("Cricetulus griseus (Chinese hamster)") - 2017/08/06 2017/08/10 rogid:EjEqEJckYyHeCg3ANFDSFlfd85E9606 rogid:EjEqEJckYyHeCg3ANFDSFlfd85E9606 rigid:bdjsOWnHiMV+GIaLcrVPGSGArSI false flag tag:c-c myc tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q96G30 uniprotkb:Q96G30 intact:EBI-9537218|uniprotkb:A8K9M1|uniprotkb:Q8IXM9|uniprotkb:Q8N2D1|ensembl:ENSP00000257776 intact:EBI-9537218|uniprotkb:A8K9M1|uniprotkb:Q8IXM9|uniprotkb:Q8N2D1|ensembl:ENSP00000257776 psi-mi:mrap2_human(display_long)|uniprotkb:MRAP2(gene name)|psi-mi:MRAP2(display_short)|uniprotkb:C6orf117(gene name synonym) psi-mi:mrap2_human(display_long)|uniprotkb:MRAP2(gene name)|psi-mi:MRAP2(display_short)|uniprotkb:C6orf117(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chan et al. (2009) pubmed:19329486|doi:10.1073/pnas.0809918106|imex:IM-14700 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15766182|imex:IM-14700-13|dip:DIP-103737E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_016865709.1|refseq:NP_001333470.1|refseq:NP_001333471.1|refseq:NP_001333473.1|refseq:NP_612418.2|dip:DIP-48793N|ensembl:ENSG00000135324(gene)|ensembl:ENST00000257776(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006112"(energy reserve metabolic process)|go:"GO:0007631"(feeding behavior)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030545"(signaling receptor regulator activity)|go:"GO:0031780"(corticotropin hormone receptor binding)|go:"GO:0031781"(type 3 melanocortin receptor binding)|go:"GO:0031782"(type 4 melanocortin receptor binding)|go:"GO:0031783"(type 5 melanocortin receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0070996"(type 1 melanocortin receptor binding)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0097009"(energy homeostasis)|go:"GO:0106070"(regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0106071"(positive regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0106072"(negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|interpro:IPR028111 refseq:XP_016865709.1|refseq:NP_001333470.1|refseq:NP_001333471.1|refseq:NP_001333473.1|refseq:NP_612418.2|dip:DIP-48793N|ensembl:ENSG00000135324(gene)|ensembl:ENST00000257776(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006112"(energy reserve metabolic process)|go:"GO:0007631"(feeding behavior)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030545"(signaling receptor regulator activity)|go:"GO:0031780"(corticotropin hormone receptor binding)|go:"GO:0031781"(type 3 melanocortin receptor binding)|go:"GO:0031782"(type 4 melanocortin receptor binding)|go:"GO:0031783"(type 5 melanocortin receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0070996"(type 1 melanocortin receptor binding)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0097009"(energy homeostasis)|go:"GO:0106070"(regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0106071"(positive regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0106072"(negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|interpro:IPR028111 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr)|taxid:10029("Cricetulus griseus (Chinese hamster)") - 2017/08/06 2017/08/10 rogid:EjEqEJckYyHeCg3ANFDSFlfd85E9606 rogid:EjEqEJckYyHeCg3ANFDSFlfd85E9606 rigid:bdjsOWnHiMV+GIaLcrVPGSGArSI false flag tag:c-c myc tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q8TCY5 uniprotkb:Q96G30 intact:EBI-9538727|uniprotkb:Q5EBR3|uniprotkb:Q8TDB7|uniprotkb:Q8WXC1|uniprotkb:Q8WXC2|ensembl:ENSP00000306697|ensembl:ENSP00000382684 intact:EBI-9537218|uniprotkb:A8K9M1|uniprotkb:Q8IXM9|uniprotkb:Q8N2D1|ensembl:ENSP00000257776 psi-mi:mrap_human(display_long)|uniprotkb:MRAP(gene name)|psi-mi:MRAP(display_short)|uniprotkb:B27(gene name synonym)|uniprotkb:C21orf61(gene name synonym)|uniprotkb:FALP(gene name synonym)|uniprotkb:Fat cell-specific low molecular weight protein(gene name synonym)|uniprotkb:Fat tissue-specific low MW protein(gene name synonym) psi-mi:mrap2_human(display_long)|uniprotkb:MRAP2(gene name)|psi-mi:MRAP2(display_short)|uniprotkb:C6orf117(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chan et al. (2009) pubmed:19329486|doi:10.1073/pnas.0809918106|imex:IM-14700 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15766266|imex:IM-14700-17|dip:DIP-103738E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_016883896.1|refseq:NP_001272323.1|refseq:NP_848932.1|refseq:NP_996781.1|refseq:XP_006724091.1|dip:DIP-29948N|ensembl:ENSG00000170262(gene)|ensembl:ENST00000303645(transcript)|ensembl:ENST00000399784(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030545"(signaling receptor regulator activity)|go:"GO:0031780"(corticotropin hormone receptor binding)|go:"GO:0031781"(type 3 melanocortin receptor binding)|go:"GO:0031782"(type 4 melanocortin receptor binding)|go:"GO:0031783"(type 5 melanocortin receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0070996"(type 1 melanocortin receptor binding)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0106070"(regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0106072"(negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|interpro:IPR028111|go:"GO:0106071"(positive regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway) refseq:XP_016865709.1|refseq:NP_001333470.1|refseq:NP_001333471.1|refseq:NP_001333473.1|refseq:NP_612418.2|dip:DIP-48793N|ensembl:ENSG00000135324(gene)|ensembl:ENST00000257776(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006112"(energy reserve metabolic process)|go:"GO:0007631"(feeding behavior)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030545"(signaling receptor regulator activity)|go:"GO:0031780"(corticotropin hormone receptor binding)|go:"GO:0031781"(type 3 melanocortin receptor binding)|go:"GO:0031782"(type 4 melanocortin receptor binding)|go:"GO:0031783"(type 5 melanocortin receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0070996"(type 1 melanocortin receptor binding)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0097009"(energy homeostasis)|go:"GO:0106070"(regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0106071"(positive regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0106072"(negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|interpro:IPR028111 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr)|taxid:10029("Cricetulus griseus (Chinese hamster)") - 2017/08/06 2017/08/10 rogid:Jx6MGR2o7drwH3LVeo3hbAMW72I9606 rogid:EjEqEJckYyHeCg3ANFDSFlfd85E9606 rigid:xXxieZTO35aWb87/6mNpRpTWDPY false flag tag:c-c myc tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P33032 uniprotkb:Q8TCY5 intact:EBI-9538507|uniprotkb:B0YJ34|uniprotkb:Q502V1|ensembl:ENSP00000318077|ensembl:ENSP00000468086 intact:EBI-9538727|uniprotkb:Q5EBR3|uniprotkb:Q8TDB7|uniprotkb:Q8WXC1|uniprotkb:Q8WXC2|ensembl:ENSP00000306697|ensembl:ENSP00000382684 psi-mi:mc5r_human(display_long)|uniprotkb:MC5R(gene name)|psi-mi:MC5R(display_short)|uniprotkb:MC-2(gene name synonym) psi-mi:mrap_human(display_long)|uniprotkb:MRAP(gene name)|psi-mi:MRAP(display_short)|uniprotkb:B27(gene name synonym)|uniprotkb:C21orf61(gene name synonym)|uniprotkb:FALP(gene name synonym)|uniprotkb:Fat cell-specific low molecular weight protein(gene name synonym)|uniprotkb:Fat tissue-specific low MW protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chan et al. (2009) pubmed:19329486|doi:10.1073/pnas.0809918106|imex:IM-14700 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15766245|imex:IM-14700-16|dip:DIP-103736E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005904.1|dip:DIP-48792N|ensembl:ENSG00000176136(gene)|ensembl:ENST00000324750(transcript)|ensembl:ENST00000589410(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004977"(melanocortin receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0019222"(regulation of metabolic process)|go:"GO:0042562"(hormone binding)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000621(Melanocortin 5 receptor)|interpro:IPR001671(Melanocortin/ACTH receptor)|interpro:IPR001908(Melanocortin receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-HSA-375276|reactome:R-HSA-418555|reactome:R-HSA-9660821 refseq:XP_016883896.1|refseq:NP_001272323.1|refseq:NP_848932.1|refseq:NP_996781.1|refseq:XP_006724091.1|dip:DIP-29948N|ensembl:ENSG00000170262(gene)|ensembl:ENST00000303645(transcript)|ensembl:ENST00000399784(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030545"(signaling receptor regulator activity)|go:"GO:0031780"(corticotropin hormone receptor binding)|go:"GO:0031781"(type 3 melanocortin receptor binding)|go:"GO:0031782"(type 4 melanocortin receptor binding)|go:"GO:0031783"(type 5 melanocortin receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0070996"(type 1 melanocortin receptor binding)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0106070"(regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0106072"(negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|interpro:IPR028111|go:"GO:0106071"(positive regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr)|taxid:10029("Cricetulus griseus (Chinese hamster)") - 2017/08/06 2017/08/10 rogid:uCeQ+zh9889q7riyd00rSGLwXKA9606 rogid:Jx6MGR2o7drwH3LVeo3hbAMW72I9606 rigid:kjjS++V1aJDekbNtiZWu1fsaOEE false ha tag:n-n flag tag:c-c - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P41968 uniprotkb:Q8TCY5 intact:EBI-9538510|uniprotkb:Q4KN27|uniprotkb:Q9H517|ensembl:ENSP00000243911 intact:EBI-9538727|uniprotkb:Q5EBR3|uniprotkb:Q8TDB7|uniprotkb:Q8WXC1|uniprotkb:Q8WXC2|ensembl:ENSP00000306697|ensembl:ENSP00000382684 psi-mi:mc3r_human(display_long)|uniprotkb:MC3R(gene name)|psi-mi:MC3R(display_short) psi-mi:mrap_human(display_long)|uniprotkb:MRAP(gene name)|psi-mi:MRAP(display_short)|uniprotkb:B27(gene name synonym)|uniprotkb:C21orf61(gene name synonym)|uniprotkb:FALP(gene name synonym)|uniprotkb:Fat cell-specific low molecular weight protein(gene name synonym)|uniprotkb:Fat tissue-specific low MW protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chan et al. (2009) pubmed:19329486|doi:10.1073/pnas.0809918106|imex:IM-14700 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15766224|imex:IM-14700-15|dip:DIP-103734E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_063941.3|dip:DIP-48790N|ensembl:ENSG00000124089(gene)|ensembl:ENST00000243911(transcript)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004977"(melanocortin receptor activity)|go:"GO:0004980"(melanocyte-stimulating hormone receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0017046"(peptide hormone binding)|go:"GO:0019222"(regulation of metabolic process)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042309"(homoiothermy)|go:"GO:0042923"(neuropeptide binding)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0055078"(sodium ion homeostasis)|go:"GO:0060259"(regulation of feeding behavior)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001671(Melanocortin/ACTH receptor)|interpro:IPR001908(Melanocortin receptor)|interpro:IPR002122(Melanocortin 3 receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-HSA-375276|reactome:R-HSA-418555|reactome:R-HSA-9660821 refseq:XP_016883896.1|refseq:NP_001272323.1|refseq:NP_848932.1|refseq:NP_996781.1|refseq:XP_006724091.1|dip:DIP-29948N|ensembl:ENSG00000170262(gene)|ensembl:ENST00000303645(transcript)|ensembl:ENST00000399784(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030545"(signaling receptor regulator activity)|go:"GO:0031780"(corticotropin hormone receptor binding)|go:"GO:0031781"(type 3 melanocortin receptor binding)|go:"GO:0031782"(type 4 melanocortin receptor binding)|go:"GO:0031783"(type 5 melanocortin receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0070996"(type 1 melanocortin receptor binding)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0106070"(regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0106072"(negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|interpro:IPR028111|go:"GO:0106071"(positive regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr)|taxid:10029("Cricetulus griseus (Chinese hamster)") - 2017/08/06 2017/08/10 rogid:SPh+bWidDfIyPMfxKka6vVQ1q3U9606 rogid:Jx6MGR2o7drwH3LVeo3hbAMW72I9606 rigid:E45b8WkwcXtLFN5S1rwq9D6SLuE false ha tag:n-n flag tag:c-c - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32245 uniprotkb:Q96G30 intact:EBI-3910694|uniprotkb:B2RAC3|uniprotkb:Q16317|uniprotkb:Q3MIJ6|ensembl:ENSP00000299766 intact:EBI-9537218|uniprotkb:A8K9M1|uniprotkb:Q8IXM9|uniprotkb:Q8N2D1|ensembl:ENSP00000257776 psi-mi:mc4r_human(display_long)|uniprotkb:MC4R(gene name)|psi-mi:MC4R(display_short) psi-mi:mrap2_human(display_long)|uniprotkb:MRAP2(gene name)|psi-mi:MRAP2(display_short)|uniprotkb:C6orf117(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chan et al. (2009) pubmed:19329486|doi:10.1073/pnas.0809918106|imex:IM-14700 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15766203|imex:IM-14700-14|dip:DIP-103731E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005903.2|ensembl:ENSG00000166603(gene)|ensembl:ENST00000299766(transcript)|go:"GO:0002024"(diet induced thermogenesis)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004977"(melanocortin receptor activity)|go:"GO:0004980"(melanocyte-stimulating hormone receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006112"(energy reserve metabolic process)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007631"(feeding behavior)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017046"(peptide hormone binding)|go:"GO:0019222"(regulation of metabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042923"(neuropeptide binding)|go:"GO:0045780"(positive regulation of bone resorption)|go:"GO:2000252"(negative regulation of feeding behavior)|go:"GO:0005886"(plasma membrane)|go:"GO:2000821"(regulation of grooming behavior)|interpro:IPR000155(Melanocortin 4 receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001671(Melanocortin/ACTH receptor)|interpro:IPR001908(Melanocortin receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|rcsb pdb:2IQP|rcsb pdb:2IQR|rcsb pdb:2IQS|rcsb pdb:2IQU|rcsb pdb:2IQV|rcsb pdb:2IQW|rcsb pdb:6W25|rcsb pdb:7AUE|reactome:R-HSA-375276|reactome:R-HSA-418555|reactome:R-HSA-9660821|dip:DIP-48791N refseq:XP_016865709.1|refseq:NP_001333470.1|refseq:NP_001333471.1|refseq:NP_001333473.1|refseq:NP_612418.2|dip:DIP-48793N|ensembl:ENSG00000135324(gene)|ensembl:ENST00000257776(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006112"(energy reserve metabolic process)|go:"GO:0007631"(feeding behavior)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030545"(signaling receptor regulator activity)|go:"GO:0031780"(corticotropin hormone receptor binding)|go:"GO:0031781"(type 3 melanocortin receptor binding)|go:"GO:0031782"(type 4 melanocortin receptor binding)|go:"GO:0031783"(type 5 melanocortin receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0070996"(type 1 melanocortin receptor binding)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0097009"(energy homeostasis)|go:"GO:0106070"(regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0106071"(positive regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0106072"(negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|interpro:IPR028111 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr)|taxid:10029("Cricetulus griseus (Chinese hamster)") - 2017/08/06 2017/08/10 rogid:Ugo3YVG2pY/auS33oQ3tB1jZK9w9606 rogid:EjEqEJckYyHeCg3ANFDSFlfd85E9606 rigid:PGPZ4qubwLrbXTdTJuBIHOrizgQ false ha tag:n-n myc tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)