#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P52917 uniprotkb:P52917 intact:EBI-20475|uniprotkb:D6W4H4|ensemblfungi:YPR173C intact:EBI-20475|uniprotkb:D6W4H4|ensemblfungi:YPR173C psi-mi:vps4_yeast(display_long)|uniprotkb:VPS4(gene name)|psi-mi:VPS4(display_short)|uniprotkb:CSC1(gene name synonym)|uniprotkb:END13(gene name synonym)|uniprotkb:GRD13(gene name synonym)|uniprotkb:DID6(gene name synonym)|uniprotkb:Protein END13(gene name synonym)|uniprotkb:DOA4-independent degradation protein 6(gene name synonym)|uniprotkb:Vacuolar protein-targeting protein 10(gene name synonym)|uniprotkb:VPL4(gene name synonym)|uniprotkb:VPT10(gene name synonym)|uniprotkb:P9705.10(orf name)|uniprotkb:YPR173C(locus name) psi-mi:vps4_yeast(display_long)|uniprotkb:VPS4(gene name)|psi-mi:VPS4(display_short)|uniprotkb:CSC1(gene name synonym)|uniprotkb:END13(gene name synonym)|uniprotkb:GRD13(gene name synonym)|uniprotkb:DID6(gene name synonym)|uniprotkb:Protein END13(gene name synonym)|uniprotkb:DOA4-independent degradation protein 6(gene name synonym)|uniprotkb:Vacuolar protein-targeting protein 10(gene name synonym)|uniprotkb:VPL4(gene name synonym)|uniprotkb:VPT10(gene name synonym)|uniprotkb:P9705.10(orf name)|uniprotkb:YPR173C(locus name) psi-mi:"MI:0071"(molecular sieving) Landsberg et al. (2009) pubmed:19278657|doi:10.1016/j.str.2008.12.020|imex:IM-11781 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15763944|imex:IM-11781-1|dip:DIP-102555E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015499.1|sgd:S000006377|ensemblfungi:YPR173C(gene)|ensemblfungi:YPR173C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0007033"(vacuole organization)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0016197"(endosomal transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045053"(protein retention in Golgi apparatus)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0061709"(reticulophagy)|go:"GO:0070676"(intralumenal vesicle formation)|go:"GO:1990621"(ESCRT IV complex)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR007330(MIT)|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR027417|interpro:IPR036181|rcsb pdb:2QP9|rcsb pdb:2QPA|rcsb pdb:2RKO|rcsb pdb:2V6X|rcsb pdb:3EIE|rcsb pdb:3EIH|rcsb pdb:3MHV|rcsb pdb:4NIQ|rcsb pdb:5FVK|rcsb pdb:5FVL|rcsb pdb:5UIE|rcsb pdb:5XMI|rcsb pdb:5XMK|rcsb pdb:6AP1|rcsb pdb:6BMF|rcsb pdb:6NDY|rcsb pdb:6OO2|reactome:R-SCE-917729|reactome:R-SCE-9668328|dip:DIP-1746N|mint:P52917 refseq:NP_015499.1|sgd:S000006377|ensemblfungi:YPR173C(gene)|ensemblfungi:YPR173C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0007033"(vacuole organization)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0016197"(endosomal transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045053"(protein retention in Golgi apparatus)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0061709"(reticulophagy)|go:"GO:0070676"(intralumenal vesicle formation)|go:"GO:1990621"(ESCRT IV complex)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR007330(MIT)|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR027417|interpro:IPR036181|rcsb pdb:2QP9|rcsb pdb:2QPA|rcsb pdb:2RKO|rcsb pdb:2V6X|rcsb pdb:3EIE|rcsb pdb:3EIH|rcsb pdb:3MHV|rcsb pdb:4NIQ|rcsb pdb:5FVK|rcsb pdb:5FVL|rcsb pdb:5UIE|rcsb pdb:5XMI|rcsb pdb:5XMK|rcsb pdb:6AP1|rcsb pdb:6BMF|rcsb pdb:6NDY|rcsb pdb:6OO2|reactome:R-SCE-917729|reactome:R-SCE-9668328|dip:DIP-1746N|mint:P52917 psi-mi:"MI:0465"(dip) crc64:E65BCDB19C9510DD crc64:E65BCDB19C9510DD full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/06 2017/08/10 rogid:qXGTfZcBZ9jWOVjm6tl3wIR/ngM559292 rogid:qXGTfZcBZ9jWOVjm6tl3wIR/ngM559292 rigid:IHSEAC2JeD+B2Be6hLKk4TPfJZ8 false - - - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P52917 uniprotkb:P52917 intact:EBI-20475|uniprotkb:D6W4H4|ensemblfungi:YPR173C intact:EBI-20475|uniprotkb:D6W4H4|ensemblfungi:YPR173C psi-mi:vps4_yeast(display_long)|uniprotkb:VPS4(gene name)|psi-mi:VPS4(display_short)|uniprotkb:CSC1(gene name synonym)|uniprotkb:END13(gene name synonym)|uniprotkb:GRD13(gene name synonym)|uniprotkb:DID6(gene name synonym)|uniprotkb:Protein END13(gene name synonym)|uniprotkb:DOA4-independent degradation protein 6(gene name synonym)|uniprotkb:Vacuolar protein-targeting protein 10(gene name synonym)|uniprotkb:VPL4(gene name synonym)|uniprotkb:VPT10(gene name synonym)|uniprotkb:P9705.10(orf name)|uniprotkb:YPR173C(locus name) psi-mi:vps4_yeast(display_long)|uniprotkb:VPS4(gene name)|psi-mi:VPS4(display_short)|uniprotkb:CSC1(gene name synonym)|uniprotkb:END13(gene name synonym)|uniprotkb:GRD13(gene name synonym)|uniprotkb:DID6(gene name synonym)|uniprotkb:Protein END13(gene name synonym)|uniprotkb:DOA4-independent degradation protein 6(gene name synonym)|uniprotkb:Vacuolar protein-targeting protein 10(gene name synonym)|uniprotkb:VPL4(gene name synonym)|uniprotkb:VPT10(gene name synonym)|uniprotkb:P9705.10(orf name)|uniprotkb:YPR173C(locus name) psi-mi:"MI:0067"(light scattering) Landsberg et al. (2009) pubmed:19278657|doi:10.1016/j.str.2008.12.020|imex:IM-11781 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15763960|imex:IM-11781-2|dip:DIP-102555E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015499.1|sgd:S000006377|ensemblfungi:YPR173C(gene)|ensemblfungi:YPR173C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0007033"(vacuole organization)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0016197"(endosomal transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045053"(protein retention in Golgi apparatus)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0061709"(reticulophagy)|go:"GO:0070676"(intralumenal vesicle formation)|go:"GO:1990621"(ESCRT IV complex)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR007330(MIT)|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR027417|interpro:IPR036181|rcsb pdb:2QP9|rcsb pdb:2QPA|rcsb pdb:2RKO|rcsb pdb:2V6X|rcsb pdb:3EIE|rcsb pdb:3EIH|rcsb pdb:3MHV|rcsb pdb:4NIQ|rcsb pdb:5FVK|rcsb pdb:5FVL|rcsb pdb:5UIE|rcsb pdb:5XMI|rcsb pdb:5XMK|rcsb pdb:6AP1|rcsb pdb:6BMF|rcsb pdb:6NDY|rcsb pdb:6OO2|reactome:R-SCE-917729|reactome:R-SCE-9668328|dip:DIP-1746N|mint:P52917 refseq:NP_015499.1|sgd:S000006377|ensemblfungi:YPR173C(gene)|ensemblfungi:YPR173C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0007033"(vacuole organization)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0016197"(endosomal transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045053"(protein retention in Golgi apparatus)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0061709"(reticulophagy)|go:"GO:0070676"(intralumenal vesicle formation)|go:"GO:1990621"(ESCRT IV complex)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR007330(MIT)|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR027417|interpro:IPR036181|rcsb pdb:2QP9|rcsb pdb:2QPA|rcsb pdb:2RKO|rcsb pdb:2V6X|rcsb pdb:3EIE|rcsb pdb:3EIH|rcsb pdb:3MHV|rcsb pdb:4NIQ|rcsb pdb:5FVK|rcsb pdb:5FVL|rcsb pdb:5UIE|rcsb pdb:5XMI|rcsb pdb:5XMK|rcsb pdb:6AP1|rcsb pdb:6BMF|rcsb pdb:6NDY|rcsb pdb:6OO2|reactome:R-SCE-917729|reactome:R-SCE-9668328|dip:DIP-1746N|mint:P52917 psi-mi:"MI:0465"(dip) crc64:E65BCDB19C9510DD crc64:E65BCDB19C9510DD full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/06 2017/08/10 rogid:qXGTfZcBZ9jWOVjm6tl3wIR/ngM559292 rogid:qXGTfZcBZ9jWOVjm6tl3wIR/ngM559292 rigid:IHSEAC2JeD+B2Be6hLKk4TPfJZ8 false - - - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P52917 uniprotkb:P52917 intact:EBI-20475|uniprotkb:D6W4H4|ensemblfungi:YPR173C intact:EBI-20475|uniprotkb:D6W4H4|ensemblfungi:YPR173C psi-mi:vps4_yeast(display_long)|uniprotkb:VPS4(gene name)|psi-mi:VPS4(display_short)|uniprotkb:CSC1(gene name synonym)|uniprotkb:END13(gene name synonym)|uniprotkb:GRD13(gene name synonym)|uniprotkb:DID6(gene name synonym)|uniprotkb:Protein END13(gene name synonym)|uniprotkb:DOA4-independent degradation protein 6(gene name synonym)|uniprotkb:Vacuolar protein-targeting protein 10(gene name synonym)|uniprotkb:VPL4(gene name synonym)|uniprotkb:VPT10(gene name synonym)|uniprotkb:P9705.10(orf name)|uniprotkb:YPR173C(locus name) psi-mi:vps4_yeast(display_long)|uniprotkb:VPS4(gene name)|psi-mi:VPS4(display_short)|uniprotkb:CSC1(gene name synonym)|uniprotkb:END13(gene name synonym)|uniprotkb:GRD13(gene name synonym)|uniprotkb:DID6(gene name synonym)|uniprotkb:Protein END13(gene name synonym)|uniprotkb:DOA4-independent degradation protein 6(gene name synonym)|uniprotkb:Vacuolar protein-targeting protein 10(gene name synonym)|uniprotkb:VPL4(gene name synonym)|uniprotkb:VPT10(gene name synonym)|uniprotkb:P9705.10(orf name)|uniprotkb:YPR173C(locus name) psi-mi:"MI:0020"(transmission electron microscopy) Landsberg et al. (2009) pubmed:19278657|doi:10.1016/j.str.2008.12.020|imex:IM-11781 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15763976|imex:IM-11781-3|dip:DIP-102555E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015499.1|sgd:S000006377|ensemblfungi:YPR173C(gene)|ensemblfungi:YPR173C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0007033"(vacuole organization)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0016197"(endosomal transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045053"(protein retention in Golgi apparatus)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0061709"(reticulophagy)|go:"GO:0070676"(intralumenal vesicle formation)|go:"GO:1990621"(ESCRT IV complex)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR007330(MIT)|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR027417|interpro:IPR036181|rcsb pdb:2QP9|rcsb pdb:2QPA|rcsb pdb:2RKO|rcsb pdb:2V6X|rcsb pdb:3EIE|rcsb pdb:3EIH|rcsb pdb:3MHV|rcsb pdb:4NIQ|rcsb pdb:5FVK|rcsb pdb:5FVL|rcsb pdb:5UIE|rcsb pdb:5XMI|rcsb pdb:5XMK|rcsb pdb:6AP1|rcsb pdb:6BMF|rcsb pdb:6NDY|rcsb pdb:6OO2|reactome:R-SCE-917729|reactome:R-SCE-9668328|dip:DIP-1746N|mint:P52917 refseq:NP_015499.1|sgd:S000006377|ensemblfungi:YPR173C(gene)|ensemblfungi:YPR173C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0007033"(vacuole organization)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0016197"(endosomal transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045053"(protein retention in Golgi apparatus)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0061709"(reticulophagy)|go:"GO:0070676"(intralumenal vesicle formation)|go:"GO:1990621"(ESCRT IV complex)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR007330(MIT)|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR027417|interpro:IPR036181|rcsb pdb:2QP9|rcsb pdb:2QPA|rcsb pdb:2RKO|rcsb pdb:2V6X|rcsb pdb:3EIE|rcsb pdb:3EIH|rcsb pdb:3MHV|rcsb pdb:4NIQ|rcsb pdb:5FVK|rcsb pdb:5FVL|rcsb pdb:5UIE|rcsb pdb:5XMI|rcsb pdb:5XMK|rcsb pdb:6AP1|rcsb pdb:6BMF|rcsb pdb:6NDY|rcsb pdb:6OO2|reactome:R-SCE-917729|reactome:R-SCE-9668328|dip:DIP-1746N|mint:P52917 psi-mi:"MI:0465"(dip) crc64:E65BCDB19C9510DD crc64:E65BCDB19C9510DD full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/06 2017/08/10 rogid:qXGTfZcBZ9jWOVjm6tl3wIR/ngM559292 rogid:qXGTfZcBZ9jWOVjm6tl3wIR/ngM559292 rigid:IHSEAC2JeD+B2Be6hLKk4TPfJZ8 false - - - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)