#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q6I9S1 intact:EBI-15760986 intact:EBI-15760989 dip:DIP-48398N psi-mi:q6i9s1_human(display_long)|uniprotkb:NR1D2(gene name)|psi-mi:NR1D2(display_short) psi-mi:ncor(display_short)|psi-mi:EBI-15760986(display_long) psi-mi:"MI:0053"(fluorescence polarization spectroscopy) Pardee et al. (2009) pubmed:19243223|doi:10.1371/journal.pbio.1000043|imex:IM-14149 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15761005|imex:IM-14149-1|dip:DIP-102820E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0327"(peptide) go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|dip:DIP-48397N - psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/06 2017/08/10 rogid:kddo+EkVDzzKP29CKR9sQBgfF4I9606 rogid:njdI53naxNhRdgsCiYubdX3gGMk-2 rigid:qUhS1v7QaGdiK+Bpl9w0qyL+1kg false binding-associated region:212-579 fluorescent dye label:0-0 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) intact:EBI-15760986 uniprotkb:P20393 dip:DIP-48398N intact:EBI-2811738|uniprotkb:Q15304|uniprotkb:Q0P5Z4|ensembl:ENSP00000246672 psi-mi:ncor(display_short)|psi-mi:EBI-15760986(display_long) psi-mi:nr1d1_human(display_long)|uniprotkb:NR1D1(gene name)|psi-mi:NR1D1(display_short)|uniprotkb:EAR1(gene name synonym)|uniprotkb:HREV(gene name synonym)|uniprotkb:THRAL(gene name synonym)|uniprotkb:Rev-erbA-alpha(gene name synonym)|uniprotkb:V-erbA-related protein 1(gene name synonym) psi-mi:"MI:0053"(fluorescence polarization spectroscopy) Pardee et al. (2009) pubmed:19243223|doi:10.1371/journal.pbio.1000043|imex:IM-14149 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15761026|imex:IM-14149-2|dip:DIP-102818E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0327"(peptide) psi-mi:"MI:0326"(protein) - refseq:NP_068370.1|ensembl:ENSG00000126368(gene)|ensembl:ENST00000246672(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016604"(nuclear body)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0020037"(heme binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030425"(dendrite)|go:"GO:0031648"(protein destabilization)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0034144"(negative regulation of toll-like receptor 4 signaling pathway)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042749"(regulation of circadian sleep/wake cycle)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043197"(dendritic spine)|go:"GO:0044321"(response to leptin)|go:"GO:0045598"(regulation of fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0060086"(circadian temperature homeostasis)|go:"GO:0061178"(regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0061469"(regulation of type B pancreatic cell proliferation)|go:"GO:0061889"(negative regulation of astrocyte activation)|go:"GO:0070859"(positive regulation of bile acid biosynthetic process)|go:"GO:0070888"(E-box binding)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:0150079"(negative regulation of neuroinflammatory response)|go:"GO:1903979"(negative regulation of microglial cell activation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|rcsb pdb:1A6Y|rcsb pdb:1EF6|rcsb pdb:1GA5|rcsb pdb:1HLZ|rcsb pdb:3N00|reactome:R-HSA-1368071|reactome:R-HSA-1989781|reactome:R-HSA-2151201|reactome:R-HSA-383280|reactome:R-HSA-400253|reactome:R-HSA-9707616|dip:DIP-48396N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/06 2017/08/10 rogid:njdI53naxNhRdgsCiYubdX3gGMk-2 rogid:UfaVQzUQ3wD4xDBh1sjp+eaawY89606 rigid:hO7zJR2JtVDG/S6PrDQIxXFB3z8 false fluorescent dye label:0-0 binding-associated region:423-614,274-323 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) intact:EBI-15761048 uniprotkb:Q6I9S1 dip:DIP-48399N intact:EBI-15760989 psi-mi:smrt(display_short)|psi-mi:EBI-15761048(display_long) psi-mi:q6i9s1_human(display_long)|uniprotkb:NR1D2(gene name)|psi-mi:NR1D2(display_short) psi-mi:"MI:0053"(fluorescence polarization spectroscopy) Pardee et al. (2009) pubmed:19243223|doi:10.1371/journal.pbio.1000043|imex:IM-14149 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15761051|imex:IM-14149-3|dip:DIP-102821E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0327"(peptide) psi-mi:"MI:0326"(protein) - go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|dip:DIP-48397N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/06 2017/08/10 rogid:bN2EtNVsUkh/EMF0zPmtI/HnuKg-2 rogid:kddo+EkVDzzKP29CKR9sQBgfF4I9606 rigid:44ysFtjoowYJwKS87Y542cNvbXg false fluorescent dye label:0-0 binding-associated region:212-579 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) intact:EBI-15761048 uniprotkb:P20393 dip:DIP-48399N intact:EBI-2811738|uniprotkb:Q15304|uniprotkb:Q0P5Z4|ensembl:ENSP00000246672 psi-mi:smrt(display_short)|psi-mi:EBI-15761048(display_long) psi-mi:nr1d1_human(display_long)|uniprotkb:NR1D1(gene name)|psi-mi:NR1D1(display_short)|uniprotkb:EAR1(gene name synonym)|uniprotkb:HREV(gene name synonym)|uniprotkb:THRAL(gene name synonym)|uniprotkb:Rev-erbA-alpha(gene name synonym)|uniprotkb:V-erbA-related protein 1(gene name synonym) psi-mi:"MI:0053"(fluorescence polarization spectroscopy) Pardee et al. (2009) pubmed:19243223|doi:10.1371/journal.pbio.1000043|imex:IM-14149 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15761072|imex:IM-14149-4|dip:DIP-102819E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0327"(peptide) psi-mi:"MI:0326"(protein) - refseq:NP_068370.1|ensembl:ENSG00000126368(gene)|ensembl:ENST00000246672(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016604"(nuclear body)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0020037"(heme binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030425"(dendrite)|go:"GO:0031648"(protein destabilization)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0034144"(negative regulation of toll-like receptor 4 signaling pathway)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042749"(regulation of circadian sleep/wake cycle)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043197"(dendritic spine)|go:"GO:0044321"(response to leptin)|go:"GO:0045598"(regulation of fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0060086"(circadian temperature homeostasis)|go:"GO:0061178"(regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0061469"(regulation of type B pancreatic cell proliferation)|go:"GO:0061889"(negative regulation of astrocyte activation)|go:"GO:0070859"(positive regulation of bile acid biosynthetic process)|go:"GO:0070888"(E-box binding)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:0150079"(negative regulation of neuroinflammatory response)|go:"GO:1903979"(negative regulation of microglial cell activation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|rcsb pdb:1A6Y|rcsb pdb:1EF6|rcsb pdb:1GA5|rcsb pdb:1HLZ|rcsb pdb:3N00|reactome:R-HSA-1368071|reactome:R-HSA-1989781|reactome:R-HSA-2151201|reactome:R-HSA-383280|reactome:R-HSA-400253|reactome:R-HSA-9707616|dip:DIP-48396N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/06 2017/08/10 rogid:bN2EtNVsUkh/EMF0zPmtI/HnuKg-2 rogid:UfaVQzUQ3wD4xDBh1sjp+eaawY89606 rigid:DADAInYcf32cGf32kZxB2Fm2Ke4 false fluorescent dye label:0-0 binding-associated region:423-614,274-323 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)